BR0315347A - Derivados de alfa-fenil acetanilidas e sua aplicação em terapêutica humana - Google Patents
Derivados de alfa-fenil acetanilidas e sua aplicação em terapêutica humanaInfo
- Publication number
- BR0315347A BR0315347A BR0315347-9A BR0315347A BR0315347A BR 0315347 A BR0315347 A BR 0315347A BR 0315347 A BR0315347 A BR 0315347A BR 0315347 A BR0315347 A BR 0315347A
- Authority
- BR
- Brazil
- Prior art keywords
- derivatives
- alpha
- application
- human therapy
- phenyl acetanilide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"DERIVADOS DE ALFA-FENIL ACETANILIDAS E SUA APLICAçãO EM TERAPêUTICA HUMANA". A presente invenção refere-se a novos derivados de fórmula geral (I) na qual: - R~ 1~ representa um grupamento hidroxila ou amino - R~ 2~ representa o hidrogênio ou um radical metila - R~ 3~ representa o hidrogênio ou um átomo de flúor - A representa um grupamento (II) no qual: - n representa um número inteiro de 5 a 11 limites incluídos - R~ 4~, R~ 5~ idênticos ou diferentes representam independentemente um ou outro o hidrogênio ou um átomo de flúor (III) no qual n, R~ 4~, R~ 5~ têm a mesma significação que precedentemente. Ela também refere-se às composições farmacêuticas que compreendem a título de princípio ativo pelo menos um desses compostos, assim como à utilização desses derivados para a fabricação de medicamentos destinados ao tratamento da hipercolesterolemia ou da aterosclerose.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0212855A FR2845991B1 (fr) | 2002-10-16 | 2002-10-16 | Derives d'alpha-phenyl acetanilides et leur application en therapeutique humaine |
| PCT/FR2003/003038 WO2004035552A1 (fr) | 2002-10-16 | 2003-10-15 | Derives d’alpha-phenil acetanilides presentant une activite inhibitrice de l’acat et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0315347A true BR0315347A (pt) | 2005-08-23 |
Family
ID=32050433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0315347-9A BR0315347A (pt) | 2002-10-16 | 2003-10-15 | Derivados de alfa-fenil acetanilidas e sua aplicação em terapêutica humana |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060135785A1 (pt) |
| EP (1) | EP1558590A1 (pt) |
| JP (1) | JP2006512302A (pt) |
| CN (1) | CN1705648A (pt) |
| AU (1) | AU2003288327A1 (pt) |
| BR (1) | BR0315347A (pt) |
| CA (1) | CA2502505A1 (pt) |
| FR (1) | FR2845991B1 (pt) |
| MX (1) | MXPA05004064A (pt) |
| WO (1) | WO2004035552A1 (pt) |
| ZA (1) | ZA200502694B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2733353T3 (es) | 2007-11-09 | 2019-11-28 | Basf As | Compuestos lípidos para uso en productos cosméticos, como suplemento alimenticio o como un medicamento |
| EP2147910A1 (en) * | 2008-07-15 | 2010-01-27 | Pronova BioPharma Norge AS | Novel lipid compounds |
| US8735436B2 (en) | 2009-05-08 | 2014-05-27 | Pronova Biopharma Norge As | Polyunsaturated fatty acids for the treatment of diseases related to cardiovascular, metabolic and inflammatory disease areas |
| SG10201509127YA (en) | 2010-11-05 | 2015-12-30 | Pronova Biopharma Norge As | Methods of treatment using lipid compounds |
| CN105120842B (zh) | 2013-02-28 | 2020-12-01 | 普罗诺瓦生物医药挪威公司 | 包含脂质化合物、甘油三酯和表面活性剂的组合物以及使用它们的方法 |
| EP3288550B1 (en) | 2015-04-28 | 2024-06-05 | Basf As | Structurally enhanced fatty acids containing sulphur for their use in treating non-alcoholic steatohepatitis |
| CN105418527A (zh) * | 2015-12-28 | 2016-03-23 | 青岛友诚高新技术有限公司 | 一种具有抗乳腺导管癌活性的化合物及其制备方法、用途 |
| CN105541741A (zh) * | 2016-01-14 | 2016-05-04 | 青岛友诚高新技术有限公司 | 一种具有治疗冠心病活性的化合物及其制备方法 |
| IL308604A (en) | 2017-12-06 | 2024-01-01 | Basf As | Fatty acid antecedents for the treatment of nonalcoholic fatty liver disease |
| WO2022115207A1 (en) * | 2020-11-25 | 2022-06-02 | Trustees Of Dartmouth College | Method for attenuating neuroinflammation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69214827T2 (de) * | 1991-08-22 | 1997-03-06 | Warner Lambert Co | Tetrazolamide als acat inhibitoren |
| FR2741619B1 (fr) * | 1995-11-28 | 1998-02-13 | Pf Medicament | Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique |
-
2002
- 2002-10-16 FR FR0212855A patent/FR2845991B1/fr not_active Expired - Fee Related
-
2003
- 2003-10-15 US US10/531,234 patent/US20060135785A1/en not_active Abandoned
- 2003-10-15 JP JP2004544391A patent/JP2006512302A/ja active Pending
- 2003-10-15 EP EP03780228A patent/EP1558590A1/fr not_active Withdrawn
- 2003-10-15 WO PCT/FR2003/003038 patent/WO2004035552A1/fr not_active Application Discontinuation
- 2003-10-15 BR BR0315347-9A patent/BR0315347A/pt not_active Application Discontinuation
- 2003-10-15 AU AU2003288327A patent/AU2003288327A1/en not_active Abandoned
- 2003-10-15 CN CNA2003801016613A patent/CN1705648A/zh active Pending
- 2003-10-15 CA CA002502505A patent/CA2502505A1/fr not_active Abandoned
- 2003-10-15 MX MXPA05004064A patent/MXPA05004064A/es unknown
-
2005
- 2005-04-04 ZA ZA200502694A patent/ZA200502694B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003288327A1 (en) | 2004-05-04 |
| US20060135785A1 (en) | 2006-06-22 |
| WO2004035552A1 (fr) | 2004-04-29 |
| CN1705648A (zh) | 2005-12-07 |
| ZA200502694B (en) | 2005-11-10 |
| MXPA05004064A (es) | 2005-06-08 |
| EP1558590A1 (fr) | 2005-08-03 |
| CA2502505A1 (fr) | 2004-04-29 |
| JP2006512302A (ja) | 2006-04-13 |
| FR2845991A1 (fr) | 2004-04-23 |
| FR2845991B1 (fr) | 2005-02-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |