CN1230109A - 通过挤出法来生产固体药物剂型的方法 - Google Patents

通过挤出法来生产固体药物剂型的方法 Download PDF

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Publication number
CN1230109A
CN1230109A CN97197941A CN97197941A CN1230109A CN 1230109 A CN1230109 A CN 1230109A CN 97197941 A CN97197941 A CN 97197941A CN 97197941 A CN97197941 A CN 97197941A CN 1230109 A CN1230109 A CN 1230109A
Authority
CN
China
Prior art keywords
binder
solution
mixture
dispersion
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN97197941A
Other languages
English (en)
Chinese (zh)
Inventor
J·布雷藤巴赫
A·克莱恩克
S·科斯拉德
J·罗森贝格
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19637479A external-priority patent/DE19637479A1/de
Priority claimed from DE19734011A external-priority patent/DE19734011A1/de
Application filed by BASF SE filed Critical BASF SE
Publication of CN1230109A publication Critical patent/CN1230109A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN97197941A 1996-09-13 1997-09-11 通过挤出法来生产固体药物剂型的方法 Pending CN1230109A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19637479A DE19637479A1 (de) 1996-09-13 1996-09-13 Verfahren zur Herstellung fester pharmazeutischer Formen
DE19637479.0 1996-09-13
DE19734011A DE19734011A1 (de) 1997-08-06 1997-08-06 Verfahren zur Herstellung fester pharmazeutischer Formen
DE19734011.3 1997-08-06

Publications (1)

Publication Number Publication Date
CN1230109A true CN1230109A (zh) 1999-09-29

Family

ID=26029370

Family Applications (1)

Application Number Title Priority Date Filing Date
CN97197941A Pending CN1230109A (zh) 1996-09-13 1997-09-11 通过挤出法来生产固体药物剂型的方法

Country Status (19)

Country Link
US (1) US6221368B1 (enExample)
EP (1) EP0930875B1 (enExample)
JP (1) JP4975894B2 (enExample)
KR (1) KR20000036066A (enExample)
CN (1) CN1230109A (enExample)
AT (1) ATE239452T1 (enExample)
AU (1) AU720535B2 (enExample)
BR (1) BR9711777A (enExample)
CA (1) CA2265532C (enExample)
CZ (1) CZ82999A3 (enExample)
DE (1) DE59710059D1 (enExample)
DK (1) DK0930875T3 (enExample)
ES (1) ES2199373T3 (enExample)
HR (1) HRP970485A2 (enExample)
IL (1) IL128672A0 (enExample)
SK (1) SK26099A3 (enExample)
TR (1) TR199900563T2 (enExample)
TW (1) TW474824B (enExample)
WO (1) WO1998010752A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108421497A (zh) * 2018-04-03 2018-08-21 杨高品 药物连续化制粒的生产工艺和设备

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WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108421497A (zh) * 2018-04-03 2018-08-21 杨高品 药物连续化制粒的生产工艺和设备

Also Published As

Publication number Publication date
AU4384697A (en) 1998-04-02
JP2001500130A (ja) 2001-01-09
BR9711777A (pt) 1999-08-24
KR20000036066A (ko) 2000-06-26
WO1998010752A2 (de) 1998-03-19
HRP970485A2 (en) 1998-08-31
JP4975894B2 (ja) 2012-07-11
US6221368B1 (en) 2001-04-24
DE59710059D1 (de) 2003-06-12
ES2199373T3 (es) 2004-02-16
SK26099A3 (en) 2000-03-13
AU720535B2 (en) 2000-06-01
EP0930875A2 (de) 1999-07-28
TR199900563T2 (xx) 1999-07-21
EP0930875B1 (de) 2003-05-07
IL128672A0 (en) 2000-01-31
WO1998010752A3 (de) 1998-06-18
CA2265532A1 (en) 1998-03-19
TW474824B (en) 2002-02-01
CZ82999A3 (cs) 1999-06-16
ATE239452T1 (de) 2003-05-15
CA2265532C (en) 2006-04-04
DK0930875T3 (da) 2003-09-01

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