JP4975894B2 - 押出による固体薬剤剤形の製造方法 - Google Patents

押出による固体薬剤剤形の製造方法 Download PDF

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Publication number
JP4975894B2
JP4975894B2 JP51302098A JP51302098A JP4975894B2 JP 4975894 B2 JP4975894 B2 JP 4975894B2 JP 51302098 A JP51302098 A JP 51302098A JP 51302098 A JP51302098 A JP 51302098A JP 4975894 B2 JP4975894 B2 JP 4975894B2
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JP
Japan
Prior art keywords
binder
active ingredient
acid
dispersion
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP51302098A
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English (en)
Japanese (ja)
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JP2001500130A (ja
JP2001500130A5 (enExample
Inventor
ブライテンバッハ イェルク
クラインケ アンドレアス
コトラーデ シュテファン
ローゼンベルク イェルク
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
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Filing date
Publication date
Priority claimed from DE19637479A external-priority patent/DE19637479A1/de
Priority claimed from DE19734011A external-priority patent/DE19734011A1/de
Application filed by BASF SE filed Critical BASF SE
Publication of JP2001500130A publication Critical patent/JP2001500130A/ja
Publication of JP2001500130A5 publication Critical patent/JP2001500130A5/ja
Application granted granted Critical
Publication of JP4975894B2 publication Critical patent/JP4975894B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP51302098A 1996-09-13 1997-09-11 押出による固体薬剤剤形の製造方法 Expired - Fee Related JP4975894B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19637479A DE19637479A1 (de) 1996-09-13 1996-09-13 Verfahren zur Herstellung fester pharmazeutischer Formen
DE19637479.0 1996-09-13
DE19734011.3 1997-08-06
DE19734011A DE19734011A1 (de) 1997-08-06 1997-08-06 Verfahren zur Herstellung fester pharmazeutischer Formen
PCT/EP1997/004984 WO1998010752A2 (de) 1996-09-13 1997-09-11 Verfahren zur herstellung fester pharmazeutischer formen durch extrudierung

Publications (3)

Publication Number Publication Date
JP2001500130A JP2001500130A (ja) 2001-01-09
JP2001500130A5 JP2001500130A5 (enExample) 2005-04-07
JP4975894B2 true JP4975894B2 (ja) 2012-07-11

Family

ID=26029370

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51302098A Expired - Fee Related JP4975894B2 (ja) 1996-09-13 1997-09-11 押出による固体薬剤剤形の製造方法

Country Status (19)

Country Link
US (1) US6221368B1 (enExample)
EP (1) EP0930875B1 (enExample)
JP (1) JP4975894B2 (enExample)
KR (1) KR20000036066A (enExample)
CN (1) CN1230109A (enExample)
AT (1) ATE239452T1 (enExample)
AU (1) AU720535B2 (enExample)
BR (1) BR9711777A (enExample)
CA (1) CA2265532C (enExample)
CZ (1) CZ82999A3 (enExample)
DE (1) DE59710059D1 (enExample)
DK (1) DK0930875T3 (enExample)
ES (1) ES2199373T3 (enExample)
HR (1) HRP970485A2 (enExample)
IL (1) IL128672A0 (enExample)
SK (1) SK26099A3 (enExample)
TR (1) TR199900563T2 (enExample)
TW (1) TW474824B (enExample)
WO (1) WO1998010752A2 (enExample)

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WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
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US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
CA2547597A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate compositions with improved stability
KR20080064209A (ko) * 2003-12-04 2008-07-08 화이자 프로덕츠 인코포레이티드 바람직하게는 폴록사머와 글리세라이드를 함유하는다미립자 아지트로마이신 조성물의 제조를 위해 압출기를사용하는 분무응결 방법
CN1889933A (zh) * 2003-12-04 2007-01-03 辉瑞产品公司 由基于液体的工艺制备的阿奇霉素多颗粒剂型
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
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WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
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CN108421497A (zh) * 2018-04-03 2018-08-21 杨高品 药物连续化制粒的生产工艺和设备
KR20250119038A (ko) 2024-01-31 2025-08-07 주식회사 이엔케이글로벌 신축성재질 성형틀 기반의 고흡수성 고형 제형 흡습제 제조 장비
KR102757752B1 (ko) 2024-01-31 2025-01-21 (주) 제이아리 강성재질 성형틀 기반의 고형 제형 흡습제 제조 장비
KR102857226B1 (ko) 2024-02-01 2025-09-09 (주) 제이아리 고흡수성 고형 제형 흡습제 제조 장비

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Also Published As

Publication number Publication date
EP0930875A2 (de) 1999-07-28
KR20000036066A (ko) 2000-06-26
JP2001500130A (ja) 2001-01-09
ES2199373T3 (es) 2004-02-16
TW474824B (en) 2002-02-01
WO1998010752A2 (de) 1998-03-19
WO1998010752A3 (de) 1998-06-18
HRP970485A2 (en) 1998-08-31
SK26099A3 (en) 2000-03-13
AU720535B2 (en) 2000-06-01
BR9711777A (pt) 1999-08-24
ATE239452T1 (de) 2003-05-15
US6221368B1 (en) 2001-04-24
CA2265532C (en) 2006-04-04
CA2265532A1 (en) 1998-03-19
AU4384697A (en) 1998-04-02
TR199900563T2 (xx) 1999-07-21
DE59710059D1 (de) 2003-06-12
IL128672A0 (en) 2000-01-31
DK0930875T3 (da) 2003-09-01
CN1230109A (zh) 1999-09-29
EP0930875B1 (de) 2003-05-07
CZ82999A3 (cs) 1999-06-16

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