CN1206978C - 抗龋齿口腔用组合物，制备方法及用途 - Google Patents

抗龋齿口腔用组合物，制备方法及用途 Download PDF

Info

Publication number
CN1206978C
CN1206978C CNB971969965A CN97196996A CN1206978C CN 1206978 C CN1206978 C CN 1206978C CN B971969965 A CNB971969965 A CN B971969965A CN 97196996 A CN97196996 A CN 97196996A CN 1206978 C CN1206978 C CN 1206978C
Authority
CN
China
Prior art keywords
arginine
oral composition
calcium
phytate
oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB971969965A
Other languages
English (en)
Chinese (zh)
Other versions
CN1227483A (zh
Inventor
I·克莱伯格
A·M·阿克威多
R·查特杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of the State University of New York
Original Assignee
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of the State University of New York filed Critical Research Foundation of the State University of New York
Publication of CN1227483A publication Critical patent/CN1227483A/zh
Application granted granted Critical
Publication of CN1206978C publication Critical patent/CN1206978C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Confectionery (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CNB971969965A 1996-03-05 1997-03-04 抗龋齿口腔用组合物，制备方法及用途 Expired - Lifetime CN1206978C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/611,206 US5762911A (en) 1996-03-05 1996-03-05 Anti-caries oral compositions
US08/611,206 1996-03-05

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNB2005100727356A Division CN1305530C (zh) 1996-03-05 1997-03-04 抗龋齿口腔用组合物

Publications (2)

Publication Number Publication Date
CN1227483A CN1227483A (zh) 1999-09-01
CN1206978C true CN1206978C (zh) 2005-06-22

Family

ID=24448051

Family Applications (2)

Application Number Title Priority Date Filing Date
CNB971969965A Expired - Lifetime CN1206978C (zh) 1996-03-05 1997-03-04 抗龋齿口腔用组合物，制备方法及用途
CNB2005100727356A Expired - Lifetime CN1305530C (zh) 1996-03-05 1997-03-04 抗龋齿口腔用组合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB2005100727356A Expired - Lifetime CN1305530C (zh) 1996-03-05 1997-03-04 抗龋齿口腔用组合物

Country Status (14)

Country Link
US (2) US5762911A (enExample)
EP (1) EP0928184B1 (enExample)
JP (2) JP3980645B2 (enExample)
CN (2) CN1206978C (enExample)
AT (1) ATE432685T1 (enExample)
AU (1) AU719465B2 (enExample)
BR (1) BR9711797B1 (enExample)
CA (1) CA2252071C (enExample)
DE (1) DE69739440D1 (enExample)
DK (1) DK0928184T3 (enExample)
ES (1) ES2328301T3 (enExample)
NZ (1) NZ332172A (enExample)
PT (1) PT928184E (enExample)
WO (1) WO1997032565A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101939292B (zh) * 2008-02-08 2014-07-23 高露洁-棕榄公司 盐的生产方法

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436370B1 (en) * 1999-06-23 2002-08-20 The Research Foundation Of State University Of New York Dental anti-hypersensitivity composition and method
AU2002227247A1 (en) * 2000-12-08 2002-06-18 Brown, Dale G. Biofilm therapy process and elements
CA2524087A1 (en) * 2003-04-30 2004-11-11 Asahi Breweries, Ltd. Material for inhibiting enamel decalcification
US20040258629A1 (en) * 2003-06-23 2004-12-23 Boyd Thomas J. Antiplaque confectionery dental composition
DK1635774T4 (da) 2003-06-23 2011-05-30 Colgate Palmolive Co Stabile tandplejesammensætninger
US8287843B2 (en) 2003-06-23 2012-10-16 Colgate-Palmolive Company Antiplaque oral care compositions
US7198653B2 (en) 2003-07-31 2007-04-03 Delavau Llc Calcium carbonate granulation
CN102358746A (zh) * 2005-12-16 2012-02-22 戴维·坎纳尔 表面活性钙磷酸盐
US20070212449A1 (en) * 2006-03-02 2007-09-13 Shamsuddin Abulkalam M Reduction of the titratable acidity and the prevention of tooth and other bone degeneration
RU2008148329A (ru) 2006-05-09 2010-06-20 Колгейт-Палмолив Компани (US) Система ухода за ротовой полостью
US20080274065A1 (en) * 2006-05-09 2008-11-06 Richard Scott Robinson Oral Care Regimen
US9138414B1 (en) 2006-09-15 2015-09-22 Delavau Llc Calcium supplement having enhanced absorption
WO2008140476A2 (en) * 2006-10-31 2008-11-20 Oroscience, Inc. Process to form nano-sized materials, the compositions and uses thereof
US20080267891A1 (en) * 2007-04-30 2008-10-30 Colgate-Palmolive Company Oral Care Composition To Reduce Or Eliminate Dental Sensitivity
US20090053267A1 (en) * 2007-08-20 2009-02-26 Depierro Karen Dentifrice composition containing silicone oil beads
EP2070422A1 (en) 2007-12-05 2009-06-17 Südzucker Aktiengesellschaft Mannheim/Ochsenfurt Confectionery products promoting dental health
TWI457141B (zh) 2008-02-08 2014-10-21 美國棕欖公司 雙組分口腔保健產品
WO2009100272A2 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Effervescent compositions
BRPI0907103A2 (pt) * 2008-02-08 2016-05-03 Colgate Palmolive Co método para tratamento de dentes sensíveis, composição de selante dental, e, uso de um aminoácido básico em forma livre ou em forma de sal.
EP2249790A4 (en) * 2008-02-08 2014-02-19 Colgate Palmolive Co BASIC AMINO ACID AND A SOLUBLE CARBONATE SALT CONTAINING COMPOSITIONS
AU2013200182B2 (en) * 2008-02-08 2015-05-21 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
US20090202452A1 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Oral care regimen
AU2009212319B2 (en) * 2008-02-08 2012-11-15 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
TWI374756B (en) * 2008-02-08 2012-10-21 Colgate Palmolive Co Compositions and methods comprising basic amino acid peptides and proteases
JP5606328B2 (ja) * 2008-02-08 2014-10-15 コルゲート・パーモリブ・カンパニー 口腔ケア歯ブラシ
AU2009212337B2 (en) * 2008-02-08 2012-01-12 Colgate-Palmolive Company Cleaning compositions and methods
RU2482835C2 (ru) * 2008-02-08 2013-05-27 Колгейт-Палмолив Компани Продукт для ухода за ротовой полостью и способы его применения и изготовления
EP2252169A4 (en) * 2008-02-08 2013-08-21 Colgate Palmolive Co ARGINE-CONTAINING DRINK
US20100322987A1 (en) * 2008-02-08 2010-12-23 Colgate-Palmolive Company Dental wipe
BRPI0907107B8 (pt) * 2008-02-08 2019-08-20 Colgate Palmolive Co composição, e, uso de uma composição para cuidado oral
JP2011511667A (ja) 2008-02-08 2011-04-14 コルゲート・パーモリブ・カンパニー デンタルフロス
EP2240153A1 (en) * 2008-02-08 2010-10-20 Colgate-Palmolive Company Oral care regimen
WO2009100275A2 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Compositions and devices
AU2012211481B2 (en) * 2008-02-08 2013-08-22 Colgate-Palmolive Company Arginine salts and their uses for the treatment of illnesses in the oral cavity
WO2009100265A2 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Compositions and methods for the treatment of xerostomia
AU2009212333C1 (en) * 2008-02-08 2012-07-19 Colgate-Palmolive Company Compositions and devices
AU2008349846B2 (en) * 2008-02-08 2012-05-31 Colgate-Palmolive Company Arginine salts and their uses for the treatment of illnesses in the oral cavity
CA2828861A1 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
BRPI0821860B1 (pt) * 2008-02-08 2016-11-01 Colgate Palmolive Co composição para cuidado oral, e, usos de uma composição e de um aminoácido básico, em forma livre ou de sal
WO2009100262A2 (en) * 2008-02-08 2009-08-13 Colgate-Palmolive Company Oral care methods and systems
AU2015215853B2 (en) * 2008-02-08 2016-11-03 Colgate-Palmolive Company Oral care product and methods of use and manufacture thereof
AR070591A1 (es) * 2008-02-08 2010-04-21 Colgate Palmolive Co Producto para el cuidado bucal y metodos de uso y preparacion de los mismos
US20090005320A1 (en) * 2008-09-02 2009-01-01 Bruce Kneller Compositions comprising amino acid bicarbonate and methods of use thereof
AU2009324944B2 (en) * 2008-11-25 2014-10-16 The Procter & Gamble Company Improved cleaning oral care compositions
WO2010134904A1 (en) * 2009-05-18 2010-11-25 Colgate-Palmolive Company Oral compositions containing polyguanidinium compounds and methods of manufacture and use thereof
US8741268B2 (en) * 2009-09-10 2014-06-03 Preventive Technologies, Inc. Dental prophylactic paste
TWI499430B (zh) 2009-12-17 2015-09-11 美國棕欖公司 抗侵蝕的牙膏組成物
RU2528051C2 (ru) 2009-12-18 2014-09-10 Колгейт-Палмолив Компани Способы получения бикарбоната аргинина при низком давлении
JP2013514357A (ja) 2009-12-18 2013-04-25 コルゲート・パーモリブ・カンパニー 高圧での高濃度の重炭酸アルギニン溶液の製造方法
AU2010337087B2 (en) 2009-12-29 2016-09-22 W. R. Grace & Co.-Conn. Compositions for forming obscuration films and methods of making and using the same
JP5727517B2 (ja) 2010-01-29 2015-06-03 コルゲート・パーモリブ・カンパニーＣｏｌｇａｔｅ−Ｐａｌｍｏｌｉｖｅ Ｃｏｍｐａｎｙ 敏感なエナメル質のケアのための口腔ケア製品
US8658139B1 (en) 2010-02-27 2014-02-25 Squigle, Inc. Prevention and treatment of oral diseases
DE102010003280A1 (de) 2010-03-25 2011-02-03 Henkel Ag & Co. Kgaa Mund- und Zahnpflege- und -reinigungsmittel mit pflanzlichen Peptiden
MX2012013955A (es) 2010-06-23 2013-01-24 Colgate Palmolive Co Composiciones terapeuticas bucales.
US9717929B2 (en) * 2010-12-07 2017-08-01 Colgate-Palmolive Company Dentifrice compositions containing calcium silicate and a basic amino acid
US9107838B2 (en) 2012-04-25 2015-08-18 Therametrics Technologies, Inc. Fluoride varnish
US12146130B2 (en) 2012-09-04 2024-11-19 Blue Planet Systems Corporation Carbon sequestration methods and systems, and compositions produced thereby
JP6329952B2 (ja) 2012-09-04 2018-05-23 ブルー プラネット，エルティーディー． 炭素隔離方法およびシステム、ならびにそれにより生成された組成物
EP2928450B1 (en) 2012-12-06 2017-03-01 Colgate-Palmolive Company Oral gel for sensitivity and tooth pain
US10203434B2 (en) 2013-03-15 2019-02-12 Blue Planet, Ltd. Highly reflective microcrystalline/amorphous materials, and methods for making and using the same
GB2516702B (en) * 2013-07-19 2015-09-02 Basf Enzymes Llc Colorimetric Phytic Acid Assay
ES2486441B1 (es) 2014-04-02 2015-06-11 Universitat De Les Illes Balears Preparaciones combinadas de acidificantes urinarios e inhibidores de la cristalización y su aplicación para el tratamiento o prevención de la litiasis renal fosfática o inducida por fosfato cálcico
BR112017012636B1 (pt) 2014-12-23 2021-01-19 Colgate-Palmolive Company composição de cuidado oral e uso de aminoácido básico na forma livre ou de sal, carbonato de cálcio, uma fonte de íons fluoreto e um agente aromatizante compreendendo menos de 50% de mentol e um surfactante aniônico
WO2021062607A1 (en) 2019-09-30 2021-04-08 The Procter & Gamble Company Oral care compositions comprising hops beta acid and amino acid
AU2020359102B2 (en) 2019-09-30 2024-03-14 The Procter & Gamble Company Oral care compositions comprising hops beta acid and fluoride
CA3155923A1 (en) 2019-09-30 2021-04-08 The Procter & Gamble Company FLUORIDE-FREE ANTI-CAVITY ORAL CARE COMPOSITIONS
CN116209418A (zh) 2020-09-28 2023-06-02 宝洁公司 防龋口腔护理组合物系列
JP2023542023A (ja) 2020-09-28 2023-10-04 ザ プロクター アンド ギャンブル カンパニー プレニル化フラボノイドを含む口腔ケア組成物
CN116710059A (zh) 2020-09-28 2023-09-05 宝洁公司 包含啤酒花和风味剂的口腔护理组合物
JP2023542024A (ja) 2020-09-28 2023-10-04 ザ プロクター アンド ギャンブル カンパニー ホップ－金属錯体を含む水性組成物
CA3214487A1 (en) 2021-03-25 2022-09-29 The Procter & Gamble Company Oral care compositions comprising hops
JP2024509602A (ja) 2021-03-25 2024-03-04 ザ プロクター アンド ギャンブル カンパニー ホップ及び甘味料を含む口腔ケア組成物
US20220304919A1 (en) 2021-03-25 2022-09-29 The Procter & Gamble Company Edible Oral Compositions Comprising Hops
CN115572309B (zh) * 2022-09-20 2024-05-03 浙江工业大学 一种高效阻燃、抗熔滴的环境友好型阻燃剂
WO2025000250A1 (en) 2023-06-28 2025-01-02 The Procter & Gamble Company Oral care compositions comprising hops beta acids
US20250009641A1 (en) 2023-06-28 2025-01-09 The Procter & Gamble Company Oral Care Compositions Comprising Hops Beta Acids
WO2025006664A2 (en) 2023-06-28 2025-01-02 The Procter & Gamble Company Oral care compositions comprising hops beta acids and tin
EP4777064A1 (en) 2023-09-14 2026-07-22 The Procter & Gamble Company Oral care compositions comprising hops beta acids and tin
WO2025080747A1 (en) 2023-10-11 2025-04-17 The Procter & Gamble Company Oral care compositions comprising dicarboxylic acid
CN122121851A (zh) 2023-10-11 2026-05-29 宝洁公司 包含二羧酸的口腔护理组合物
WO2025080746A1 (en) 2023-10-11 2025-04-17 The Procter & Gamble Company Oral care compositions comprising dicarboxylic acid
WO2025076709A1 (en) 2023-10-11 2025-04-17 The Procter & Gamble Company Oral care compositions comprising dicarboxylic acid
AU2024360733A1 (en) 2023-10-11 2026-03-19 The Procter & Gamble Company Oral care compositions comprising dicarboxylic acid
EP4791352A1 (en) 2023-10-11 2026-08-19 The Procter & Gamble Company Oral care compositions comprising dicarboxylic acid
WO2026060055A1 (en) 2024-09-13 2026-03-19 The Procter & Gamble Company Oral care compositions comprising mint oil and tin
WO2026060054A1 (en) 2024-09-13 2026-03-19 The Procter & Gamble Company Oral care compositions comprising hops and tin
WO2026080572A1 (en) 2024-10-10 2026-04-16 The Procter & Gamble Company Oral care compositions comprising carboxylic acids

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932608A (en) * 1971-08-30 1976-01-13 General Mills, Inc. Food composition
US3943241A (en) * 1971-08-30 1976-03-09 General Mills, Inc. Cariostatic composition
US4064138A (en) * 1975-11-12 1977-12-20 General Mills, Inc. Amino acid derivatives
USRE31181E (en) * 1976-06-18 1983-03-15 Means and method for improving natural defenses against caries
ZA773318B (en) * 1976-06-18 1978-04-26 I Kleinberg Means and method for improving natural defenses against caries
GB1573727A (en) * 1978-05-19 1980-08-28 Colgate Palmolive Co Dentifrices
US4225579A (en) * 1979-02-27 1980-09-30 Israel Kleinberg Means and method for improving defenses against caries
JPS5835965B2 (ja) * 1979-07-31 1983-08-05 ライオン株式会社 口腔用組成物
US4367218A (en) * 1979-09-06 1983-01-04 Jacobson Jerry I Anti-caries oral rinse
US4528181A (en) * 1984-02-01 1985-07-09 Colgate-Palmolive Company Dentifrice containing dual sources of fluoride
JPS61233612A (ja) * 1985-04-10 1986-10-17 Kao Corp チユ−インガム
US5370865A (en) * 1992-05-15 1994-12-06 Kao Corporation Composition for use in oral cavity
CN1094309A (zh) * 1993-04-27 1994-11-02 李颖 一种矿质吸收因子肽钙及其制剂的制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101939292B (zh) * 2008-02-08 2014-07-23 高露洁-棕榄公司 盐的生产方法

Also Published As

Publication number Publication date
JP3980645B2 (ja) 2007-09-26
EP0928184B1 (en) 2009-06-03
AU719465B2 (en) 2000-05-11
CN1701815A (zh) 2005-11-30
AU2556397A (en) 1997-09-22
BR9711797B1 (pt) 2010-12-14
EP0928184A1 (en) 1999-07-14
BR9711797A (pt) 2000-01-18
PT928184E (pt) 2009-09-09
CN1227483A (zh) 1999-09-01
US6217851B1 (en) 2001-04-17
JP2006265268A (ja) 2006-10-05
EP0928184A4 (en) 1999-10-20
CA2252071C (en) 2004-12-21
US5762911A (en) 1998-06-09
CA2252071A1 (en) 1997-09-12
DE69739440D1 (de) 2009-07-16
DK0928184T3 (da) 2009-09-28
ES2328301T3 (es) 2009-11-11
CN1305530C (zh) 2007-03-21
WO1997032565A1 (en) 1997-09-12
JP2001504083A (ja) 2001-03-27
NZ332172A (en) 2000-11-24
ATE432685T1 (de) 2009-06-15

Similar Documents

Publication Publication Date Title
CN1305530C (zh) 抗龋齿口腔用组合物
CN1298310C (zh) 含有精细研磨的天然白垩的口腔组合物
CN1053183A (zh) 口腔用稳定的锌的化合物
CN1750807A (zh) 抗过敏性、抗龋齿、抗污迹、抗斑块、超温和的口腔卫生剂
JP5973585B2 (ja) ラクトフェリン機能化表面を有する生体模倣ヒドロキシアパタイト粒子を含有するデンタルケア製品
US9005587B2 (en) Anti-bacterial and mineralizing calcium phosphate compositions
TW201628591A (zh) 包含鋅、精胺酸及絲胺酸之口腔保健組成物
CN1822810A (zh) 口腔用组合物
CN1505501A (zh) 可兼容碳酸钙的氟化物
Qiu et al. The combination of arginine and fluoride-containing bioactive glass acted synergistically in inhibiting enamel demineralization in permanent teeth
CN1222271C (zh) 抗牙垢和牙斑的牙膏组合物
CN108430922B (zh) 用于细菌聚集的粘蛋白包被的二氧化硅
JP7840078B2 (ja) 歯肉炎と歯肉退縮の治療及び口腔粘膜の修復におけるオリゴペプチドの用途
CN115177543B (zh) 一种含l-乳酸盐的抑菌防龋组合物和口腔护理用品及其制备方法和应用
CN1216061C (zh) 低钙含量的抗坏血酸2－磷酸酯金属盐
US20110097285A1 (en) Multiplex dentifrice compositions
JP2009263271A (ja) 歯周病予防乃至治療薬
CN112999100B (zh) 一种含有磷硅酸钾钙生物玻璃的抗敏抛光膏
TWI817111B (zh) 口腔清潔用組成物
CN1132467A (zh) 独立起抗菌作用的磷酸酯
CN1960704A (zh) 用于抑制牙侵蚀的含有氢氟酸的组合物
KR20120021909A (ko) 기능성 치약 조성물 및 그 제조방법
JP2004196672A (ja) 抗菌剤および抗歯周病剤
CN121177149A (zh) 一种防龋齿牙膏及其制备方法
CN114746072A (zh) 口腔护理组合物

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20050622