AU719465B2 - Anti-caries oral compositions - Google Patents
Anti-caries oral compositions Download PDFInfo
- Publication number
- AU719465B2 AU719465B2 AU25563/97A AU2556397A AU719465B2 AU 719465 B2 AU719465 B2 AU 719465B2 AU 25563/97 A AU25563/97 A AU 25563/97A AU 2556397 A AU2556397 A AU 2556397A AU 719465 B2 AU719465 B2 AU 719465B2
- Authority
- AU
- Australia
- Prior art keywords
- arginine
- calcium
- oral composition
- oral
- phytate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 125
- 230000000675 anti-caries Effects 0.000 title description 5
- 239000004475 Arginine Substances 0.000 claims abstract description 123
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims abstract description 123
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims abstract description 103
- 239000011575 calcium Substances 0.000 claims abstract description 87
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 86
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 79
- 208000002925 dental caries Diseases 0.000 claims abstract description 40
- 238000000034 method Methods 0.000 claims abstract description 38
- 150000001450 anions Chemical class 0.000 claims abstract description 32
- 230000000248 cariostatic effect Effects 0.000 claims abstract description 30
- 210000000214 mouth Anatomy 0.000 claims abstract description 11
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 claims description 86
- 235000002949 phytic acid Nutrition 0.000 claims description 85
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 42
- RYJDNPSQBGFFSF-WCCKRBBISA-N (2s)-2-amino-5-(diaminomethylideneamino)pentanoic acid;carbonic acid Chemical compound OC(O)=O.OC(=O)[C@@H](N)CCCNC(N)=N RYJDNPSQBGFFSF-WCCKRBBISA-N 0.000 claims description 24
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 21
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 20
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims description 14
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 11
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- 230000000979 retarding effect Effects 0.000 claims description 7
- 239000001569 carbon dioxide Substances 0.000 claims description 6
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- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 4
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- 239000000467 phytic acid Substances 0.000 description 11
- 230000008569 process Effects 0.000 description 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 9
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- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 2
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- WPEXVRDUEAJUGY-UHFFFAOYSA-B hexacalcium;(2,3,4,5,6-pentaphosphonatooxycyclohexyl) phosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])(=O)OC1C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C(OP([O-])([O-])=O)C1OP([O-])([O-])=O WPEXVRDUEAJUGY-UHFFFAOYSA-B 0.000 description 1
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 1
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- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 description 1
- IEECXTSVVFWGSE-UHFFFAOYSA-M iron(3+);oxygen(2-);hydroxide Chemical compound [OH-].[O-2].[Fe+3] IEECXTSVVFWGSE-UHFFFAOYSA-M 0.000 description 1
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- 239000001683 mentha spicata herb oil Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
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- 150000002772 monosaccharides Chemical class 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
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- 239000002245 particle Substances 0.000 description 1
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- 108090000765 processed proteins & peptides Proteins 0.000 description 1
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- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
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- AWUCVROLDVIAJX-GSVOUGTGSA-N sn-glycerol 3-phosphate Chemical compound OC[C@@H](O)COP(O)(O)=O AWUCVROLDVIAJX-GSVOUGTGSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Confectionery (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/611,206 US5762911A (en) | 1996-03-05 | 1996-03-05 | Anti-caries oral compositions |
| US08/611206 | 1996-03-05 | ||
| PCT/US1997/005273 WO1997032565A1 (en) | 1996-03-05 | 1997-03-04 | Anti-caries oral compositions |
Publications (2)
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|---|---|
| AU2556397A AU2556397A (en) | 1997-09-22 |
| AU719465B2 true AU719465B2 (en) | 2000-05-11 |
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|---|---|---|---|
| AU25563/97A Expired AU719465B2 (en) | 1996-03-05 | 1997-03-04 | Anti-caries oral compositions |
Country Status (14)
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| US (2) | US5762911A (enExample) |
| EP (1) | EP0928184B1 (enExample) |
| JP (2) | JP3980645B2 (enExample) |
| CN (2) | CN1206978C (enExample) |
| AT (1) | ATE432685T1 (enExample) |
| AU (1) | AU719465B2 (enExample) |
| BR (1) | BR9711797B1 (enExample) |
| CA (1) | CA2252071C (enExample) |
| DE (1) | DE69739440D1 (enExample) |
| DK (1) | DK0928184T3 (enExample) |
| ES (1) | ES2328301T3 (enExample) |
| NZ (1) | NZ332172A (enExample) |
| PT (1) | PT928184E (enExample) |
| WO (1) | WO1997032565A1 (enExample) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6436370B1 (en) * | 1999-06-23 | 2002-08-20 | The Research Foundation Of State University Of New York | Dental anti-hypersensitivity composition and method |
| AU2002227247A1 (en) * | 2000-12-08 | 2002-06-18 | Brown, Dale G. | Biofilm therapy process and elements |
| CA2524087A1 (en) * | 2003-04-30 | 2004-11-11 | Asahi Breweries, Ltd. | Material for inhibiting enamel decalcification |
| US20040258629A1 (en) * | 2003-06-23 | 2004-12-23 | Boyd Thomas J. | Antiplaque confectionery dental composition |
| US8287843B2 (en) | 2003-06-23 | 2012-10-16 | Colgate-Palmolive Company | Antiplaque oral care compositions |
| PL1635774T5 (pl) | 2003-06-23 | 2011-06-30 | Colgate Palmolive Co | Trwałe kompozycje do czyszczenia zębów |
| US7198653B2 (en) | 2003-07-31 | 2007-04-03 | Delavau Llc | Calcium carbonate granulation |
| EP1960057A4 (en) * | 2005-12-16 | 2013-03-27 | David Kannar | SURFACE ACTIVE CALCIUM PHOSPHATES |
| US20070212449A1 (en) * | 2006-03-02 | 2007-09-13 | Shamsuddin Abulkalam M | Reduction of the titratable acidity and the prevention of tooth and other bone degeneration |
| US20080274065A1 (en) * | 2006-05-09 | 2008-11-06 | Richard Scott Robinson | Oral Care Regimen |
| BRPI0711271A2 (pt) | 2006-05-09 | 2011-11-08 | Colgate Palmolive Co | método de limpeza de uma superfìcie oral, de manutenção da saúde oral e/ou de aumento da saúde oral |
| US9138414B1 (en) | 2006-09-15 | 2015-09-22 | Delavau Llc | Calcium supplement having enhanced absorption |
| EP2091505A2 (en) * | 2006-10-31 | 2009-08-26 | Oroscience, Inc | Process to form nano-sized materials, the compositions and uses thereof |
| US20080267891A1 (en) * | 2007-04-30 | 2008-10-30 | Colgate-Palmolive Company | Oral Care Composition To Reduce Or Eliminate Dental Sensitivity |
| US20090053267A1 (en) * | 2007-08-20 | 2009-02-26 | Depierro Karen | Dentifrice composition containing silicone oil beads |
| EP2070422A1 (en) | 2007-12-05 | 2009-06-17 | Südzucker Aktiengesellschaft Mannheim/Ochsenfurt | Confectionery products promoting dental health |
| EP3943064A1 (en) * | 2008-02-08 | 2022-01-26 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| BRPI0822121A2 (pt) * | 2008-02-08 | 2014-09-30 | Colgate Palmolive Co | Composição para cuidado oral, e uso da mesma |
| AU2013200182B2 (en) * | 2008-02-08 | 2015-05-21 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| PA8774301A1 (es) * | 2008-02-08 | 2009-09-17 | Colgate Palmolive Co | Regimen de cuidado bucal |
| MX2010005190A (es) * | 2008-02-08 | 2010-06-03 | Colgate Palmolive Co | Hilo dental. |
| CA2705299C (en) * | 2008-02-08 | 2016-12-06 | Richard Scott Robinson | Dental wipe |
| AU2015215853B2 (en) * | 2008-02-08 | 2016-11-03 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| MY157021A (en) * | 2008-02-08 | 2016-04-15 | Colgate Palmolive Co | Oral care product and methods of use thereof |
| EP2247278A4 (en) * | 2008-02-08 | 2014-02-19 | Colgate Palmolive Co | COMPOSITIONS AND METHODS OF CLEANING |
| MX2010005004A (es) * | 2008-02-08 | 2010-05-27 | Colgate Palmolive Co | Composiciones y dispositivos. |
| AU2008349847C1 (en) * | 2008-02-08 | 2012-12-13 | Colgate-Palmolive Company | Oral care product and methods of use and manufacture thereof |
| BRPI0907106A2 (pt) * | 2008-02-08 | 2016-05-03 | Colgate Palmolive Co | bebida, e, método para melhorar a saúde oral. |
| AR070592A1 (es) * | 2008-02-08 | 2010-04-21 | Colgate Palmolive Co | Composiciones para el blanqueamiento dental |
| CN102215811A (zh) * | 2008-02-08 | 2011-10-12 | 高露洁-棕榄公司 | 泡腾组合物 |
| AU2012211481B2 (en) * | 2008-02-08 | 2013-08-22 | Colgate-Palmolive Company | Arginine salts and their uses for the treatment of illnesses in the oral cavity |
| BRPI0907102A2 (pt) | 2008-02-08 | 2016-05-03 | Colgate Palmolive Co | composição dental, e, método para eliminar ou reduzir o desconforto e a dor associados com a hipersensibilidade da dentina |
| TWI374756B (en) * | 2008-02-08 | 2012-10-21 | Colgate Palmolive Co | Compositions and methods comprising basic amino acid peptides and proteases |
| CN101938982B (zh) * | 2008-02-08 | 2014-06-04 | 高露洁-棕榄公司 | 口腔护理产品和其使用和制备方法 |
| TWI389876B (zh) * | 2008-02-08 | 2013-03-21 | Colgate Palmolive Co | 鹽的製造方法 |
| RU2010137265A (ru) * | 2008-02-08 | 2012-03-20 | Колгейт-Палмолив Компани (US) | Новые соли и их применение |
| CN102037360B (zh) * | 2008-02-08 | 2016-10-05 | 高露洁-棕榄公司 | 口腔护理方法和系统 |
| BRPI0906462A2 (pt) * | 2008-02-08 | 2015-07-14 | Colgate Palmolive Co | Método para tratar, melhorar, inibir ou evitar boca seca, saliva artificial, uso de um aminoácido básico em forma livre ou de sal, e, aminoácido básico em forma livre ou de sal |
| BRPI0906466A2 (pt) * | 2008-02-08 | 2015-07-14 | Colgate Palmolive Co | Composição para cuidado oral, e, métodos para preparar uma composição oral, e para aplicar uma quantidade eficaz da composição oral |
| RU2481820C2 (ru) * | 2008-02-08 | 2013-05-20 | Колгейт-Палмолив Компани | Средство для ухода за полостью рта и способы его применения и изготовления |
| JP2011510095A (ja) * | 2008-02-08 | 2011-03-31 | コルゲート・パーモリブ・カンパニー | 歯用シーラント［０００１］この出願は２００８年２月８日に出願された米国一連番号６１／０２７，４２５の利益を主張し、その内容を本明細書に援用する。 |
| US20090202452A1 (en) * | 2008-02-08 | 2009-08-13 | Colgate-Palmolive Company | Oral care regimen |
| MX2010005002A (es) * | 2008-02-08 | 2010-05-24 | Colgate Palmolive Co | Cepillo de dientes para el cuidado oral. |
| US20090005320A1 (en) * | 2008-09-02 | 2009-01-01 | Bruce Kneller | Compositions comprising amino acid bicarbonate and methods of use thereof |
| US8216552B2 (en) * | 2008-11-25 | 2012-07-10 | The Procter & Gamble Company | Oral care compositions containing gel networks and fused silica |
| CN102427795A (zh) | 2009-05-18 | 2012-04-25 | 高露洁-棕榄公司 | 含有聚胍*化合物的口腔组合物及其制备和使用方法 |
| US8741268B2 (en) * | 2009-09-10 | 2014-06-03 | Preventive Technologies, Inc. | Dental prophylactic paste |
| AR079639A1 (es) | 2009-12-17 | 2012-02-08 | Colgate Palmolive Co | Composicion de pasta de dientes anti-erosiva |
| EP2513047B1 (en) | 2009-12-18 | 2015-04-01 | Colgate-Palmolive Company | Methods for production of arginine bicarbonate at low pressure |
| EP2513048B1 (en) * | 2009-12-18 | 2016-11-16 | Colgate-Palmolive Company | Methods for production of high concentration of arginine bicarbonate solution at high pressure |
| KR20170134772A (ko) | 2009-12-29 | 2017-12-06 | 더블유.알. 그레이스 앤드 캄파니-콘. | 은폐 막을 형성하기 위한 조성물, 및 이의 제조 및 사용 방법 |
| TWI446926B (zh) | 2010-01-29 | 2014-08-01 | Colgate Palmolive Co | 用於敏感性琺瑯質照護之口腔照護產品（一） |
| US8658139B1 (en) | 2010-02-27 | 2014-02-25 | Squigle, Inc. | Prevention and treatment of oral diseases |
| DE102010003280A1 (de) | 2010-03-25 | 2011-02-03 | Henkel Ag & Co. Kgaa | Mund- und Zahnpflege- und -reinigungsmittel mit pflanzlichen Peptiden |
| AU2010356102B2 (en) | 2010-06-23 | 2013-09-05 | Colgate-Palmolive Company | Therapeutic oral composition |
| US9717929B2 (en) * | 2010-12-07 | 2017-08-01 | Colgate-Palmolive Company | Dentifrice compositions containing calcium silicate and a basic amino acid |
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| US11033594B2 (en) | 2012-12-06 | 2021-06-15 | Colgate-Palmolive Company | Oral gel for sensitivity and tooth pain |
| WO2014144848A1 (en) | 2013-03-15 | 2014-09-18 | Blue Planet, Ltd. | Highly reflective microcrystalline/amorphous materials, and methods for making and using the same |
| GB2516702B (en) * | 2013-07-19 | 2015-09-02 | Basf Enzymes Llc | Colorimetric Phytic Acid Assay |
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| WO2016105389A1 (en) | 2014-12-23 | 2016-06-30 | Colgate-Palmolive Company | Oral care compositions |
| CN114449996B (zh) | 2019-09-30 | 2024-10-01 | 宝洁公司 | 包含啤酒花β酸和金属离子的口腔护理组合物 |
| WO2021062607A1 (en) | 2019-09-30 | 2021-04-08 | The Procter & Gamble Company | Oral care compositions comprising hops beta acid and amino acid |
| EP4640205A2 (en) | 2019-09-30 | 2025-10-29 | The Procter & Gamble Company | Oral care compositions comprising hops beta acid and fluoride |
| JP2023542022A (ja) | 2020-09-28 | 2023-10-04 | ザ プロクター アンド ギャンブル カンパニー | ホップ及び風味料を含む口腔ケア組成物 |
| JP2023542023A (ja) | 2020-09-28 | 2023-10-04 | ザ プロクター アンド ギャンブル カンパニー | プレニル化フラボノイドを含む口腔ケア組成物 |
| US20220096362A1 (en) | 2020-09-28 | 2022-03-31 | The Procter & Gamble Company | Aqueous Compositions Comprising Hops-Metal Complex |
| BR112023002883A2 (pt) | 2020-09-28 | 2023-04-04 | Procter & Gamble | Conjunto de composições para tratamento bucal anticárie |
| BR112023019585A2 (pt) | 2021-03-25 | 2024-02-06 | Procter & Gamble | Composições para tratamento bucal que compreendem lúpulo e adoçante |
| US20220313595A1 (en) | 2021-03-25 | 2022-10-06 | The Procter & Gamble Company | Oral Care Compositions Comprising Hops |
| CN117083053A (zh) | 2021-03-25 | 2023-11-17 | 宝洁公司 | 包含啤酒花的可食口腔组合物 |
| CN115572309B (zh) * | 2022-09-20 | 2024-05-03 | 浙江工业大学 | 一种高效阻燃、抗熔滴的环境友好型阻燃剂 |
| WO2025000250A1 (en) | 2023-06-28 | 2025-01-02 | The Procter & Gamble Company | Oral care compositions comprising hops beta acids |
| AU2024306065A1 (en) | 2023-06-28 | 2025-11-27 | The Procter & Gamble Company | Oral care compositions comprising hops beta acids and tin |
| WO2025006671A2 (en) | 2023-06-28 | 2025-01-02 | The Procter & Gamble Company | Oral care compositions comprising hops beta acids |
| US20250120890A1 (en) | 2023-09-14 | 2025-04-17 | The Procter & Gamble Company | Oral Care Compositions Comprising Hops Beta Acids And Tin |
| US20250120893A1 (en) | 2023-10-11 | 2025-04-17 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
| WO2025080746A1 (en) | 2023-10-11 | 2025-04-17 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
| US20250120896A1 (en) | 2023-10-11 | 2025-04-17 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
| US20250120897A1 (en) | 2023-10-11 | 2025-04-17 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
| WO2025076709A1 (en) | 2023-10-11 | 2025-04-17 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
| WO2025080742A1 (en) | 2023-10-11 | 2025-04-17 | The Procter & Gamble Company | Oral care compositions comprising dicarboxylic acid |
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| US4154813A (en) * | 1976-06-18 | 1979-05-15 | Israel Kleinberg | Means and method for improving natural defenses against caries |
| US4528181A (en) * | 1984-02-01 | 1985-07-09 | Colgate-Palmolive Company | Dentifrice containing dual sources of fluoride |
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| US3943241A (en) * | 1971-08-30 | 1976-03-09 | General Mills, Inc. | Cariostatic composition |
| US3932608A (en) * | 1971-08-30 | 1976-01-13 | General Mills, Inc. | Food composition |
| US4064138A (en) * | 1975-11-12 | 1977-12-20 | General Mills, Inc. | Amino acid derivatives |
| USRE31181E (en) * | 1976-06-18 | 1983-03-15 | Means and method for improving natural defenses against caries | |
| GB1573727A (en) * | 1978-05-19 | 1980-08-28 | Colgate Palmolive Co | Dentifrices |
| US4225579A (en) * | 1979-02-27 | 1980-09-30 | Israel Kleinberg | Means and method for improving defenses against caries |
| JPS5835965B2 (ja) * | 1979-07-31 | 1983-08-05 | ライオン株式会社 | 口腔用組成物 |
| US4367218A (en) * | 1979-09-06 | 1983-01-04 | Jacobson Jerry I | Anti-caries oral rinse |
| JPS61233612A (ja) * | 1985-04-10 | 1986-10-17 | Kao Corp | チユ−インガム |
| US5370865A (en) * | 1992-05-15 | 1994-12-06 | Kao Corporation | Composition for use in oral cavity |
| CN1094309A (zh) * | 1993-04-27 | 1994-11-02 | 李颖 | 一种矿质吸收因子肽钙及其制剂的制备方法 |
-
1996
- 1996-03-05 US US08/611,206 patent/US5762911A/en not_active Expired - Lifetime
-
1997
- 1997-03-04 AT AT97917135T patent/ATE432685T1/de active
- 1997-03-04 NZ NZ332172A patent/NZ332172A/xx not_active IP Right Cessation
- 1997-03-04 CN CNB971969965A patent/CN1206978C/zh not_active Expired - Lifetime
- 1997-03-04 AU AU25563/97A patent/AU719465B2/en not_active Expired
- 1997-03-04 EP EP97917135A patent/EP0928184B1/en not_active Expired - Lifetime
- 1997-03-04 JP JP53207497A patent/JP3980645B2/ja not_active Expired - Lifetime
- 1997-03-04 BR BRPI9711797-8A patent/BR9711797B1/pt not_active IP Right Cessation
- 1997-03-04 ES ES97917135T patent/ES2328301T3/es not_active Expired - Lifetime
- 1997-03-04 CN CNB2005100727356A patent/CN1305530C/zh not_active Expired - Lifetime
- 1997-03-04 DK DK97917135T patent/DK0928184T3/da active
- 1997-03-04 CA CA002252071A patent/CA2252071C/en not_active Expired - Lifetime
- 1997-03-04 PT PT97917135T patent/PT928184E/pt unknown
- 1997-03-04 WO PCT/US1997/005273 patent/WO1997032565A1/en not_active Ceased
- 1997-03-04 DE DE69739440T patent/DE69739440D1/de not_active Expired - Lifetime
-
1998
- 1998-02-19 US US09/026,132 patent/US6217851B1/en not_active Expired - Lifetime
-
2006
- 2006-06-26 JP JP2006175656A patent/JP2006265268A/ja not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4154813A (en) * | 1976-06-18 | 1979-05-15 | Israel Kleinberg | Means and method for improving natural defenses against caries |
| US4528181A (en) * | 1984-02-01 | 1985-07-09 | Colgate-Palmolive Company | Dentifrice containing dual sources of fluoride |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2252071A1 (en) | 1997-09-12 |
| WO1997032565A1 (en) | 1997-09-12 |
| EP0928184A1 (en) | 1999-07-14 |
| JP2006265268A (ja) | 2006-10-05 |
| ES2328301T3 (es) | 2009-11-11 |
| BR9711797A (pt) | 2000-01-18 |
| CA2252071C (en) | 2004-12-21 |
| CN1305530C (zh) | 2007-03-21 |
| EP0928184B1 (en) | 2009-06-03 |
| PT928184E (pt) | 2009-09-09 |
| US5762911A (en) | 1998-06-09 |
| US6217851B1 (en) | 2001-04-17 |
| EP0928184A4 (en) | 1999-10-20 |
| DE69739440D1 (de) | 2009-07-16 |
| BR9711797B1 (pt) | 2010-12-14 |
| CN1206978C (zh) | 2005-06-22 |
| AU2556397A (en) | 1997-09-22 |
| DK0928184T3 (da) | 2009-09-28 |
| NZ332172A (en) | 2000-11-24 |
| JP2001504083A (ja) | 2001-03-27 |
| JP3980645B2 (ja) | 2007-09-26 |
| ATE432685T1 (de) | 2009-06-15 |
| CN1701815A (zh) | 2005-11-30 |
| CN1227483A (zh) | 1999-09-01 |
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