CN109608543A - 稳定的多抗原结合抗体 - Google Patents

稳定的多抗原结合抗体 Download PDF

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Publication number
CN109608543A
CN109608543A CN201811254222.0A CN201811254222A CN109608543A CN 109608543 A CN109608543 A CN 109608543A CN 201811254222 A CN201811254222 A CN 201811254222A CN 109608543 A CN109608543 A CN 109608543A
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Prior art keywords
xaa xaa
antibody
antigen binding
binding antibody
aho
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CN201811254222.0A
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Chinese (zh)
Inventor
A·C·里格勒尔
L·博拉斯
R·索马维拉
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Esbatech a Novartis Co LLC
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Esbatech An Alcon Biomedical Research Unit LLC
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    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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CN201811254222.0A 2011-10-20 2012-10-19 稳定的多抗原结合抗体 Pending CN109608543A (zh)

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US201161549482P 2011-10-20 2011-10-20
US61/549,482 2011-10-20
CN201280051247.5A CN103890005A (zh) 2011-10-20 2012-10-19 稳定的多抗原结合抗体

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WO2011028952A1 (en) 2009-09-02 2011-03-10 Xencor, Inc. Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
CN103052649B (zh) 2010-07-29 2015-12-16 Xencor公司 具有修改的等电点的抗体
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