CA2850572A1 - Stable multiple antigen-binding antibody - Google Patents

Stable multiple antigen-binding antibody Download PDF

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Publication number
CA2850572A1
CA2850572A1 CA2850572A CA2850572A CA2850572A1 CA 2850572 A1 CA2850572 A1 CA 2850572A1 CA 2850572 A CA2850572 A CA 2850572A CA 2850572 A CA2850572 A CA 2850572A CA 2850572 A1 CA2850572 A1 CA 2850572A1
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CA
Canada
Prior art keywords
aho position
binding antibody
linker
antibody
multiple antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2850572A
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English (en)
French (fr)
Inventor
Astrid C. RIEGLER
Leonardo Borras
Roberto Sommavilla
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esbatech a Novartis Co LLC
Original Assignee
Esbatech a Novartis Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esbatech a Novartis Co LLC filed Critical Esbatech a Novartis Co LLC
Publication of CA2850572A1 publication Critical patent/CA2850572A1/en
Abandoned legal-status Critical Current

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K16/46—Hybrid immunoglobulins
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

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  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Molecular Biology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Neurology (AREA)
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  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
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  • Ophthalmology & Optometry (AREA)
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  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
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CA2850572A 2011-10-20 2012-10-19 Stable multiple antigen-binding antibody Abandoned CA2850572A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161549482P 2011-10-20 2011-10-20
US61/549,482 2011-10-20
PCT/EP2012/004404 WO2013056851A2 (en) 2011-10-20 2012-10-19 Stable multiple antigen-binding antibody

Publications (1)

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CA2850572A1 true CA2850572A1 (en) 2013-04-25

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Application Number Title Priority Date Filing Date
CA2850572A Abandoned CA2850572A1 (en) 2011-10-20 2012-10-19 Stable multiple antigen-binding antibody

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US (2) US20130101586A1 (enExample)
EP (2) EP3431495A1 (enExample)
JP (3) JP2014533239A (enExample)
KR (1) KR20140082700A (enExample)
CN (2) CN103890005A (enExample)
AR (1) AR088403A1 (enExample)
AU (1) AU2012325232B2 (enExample)
BR (1) BR112014009030A2 (enExample)
CA (1) CA2850572A1 (enExample)
ES (1) ES2687245T3 (enExample)
MX (1) MX2014004521A (enExample)
RU (2) RU2652886C2 (enExample)
TW (1) TWI577696B (enExample)
UY (1) UY34404A (enExample)
WO (1) WO2013056851A2 (enExample)

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