BR112014009030A2 - anticorpo de ligação a antígenos múltiplos estável - Google Patents

anticorpo de ligação a antígenos múltiplos estável

Info

Publication number
BR112014009030A2
BR112014009030A2 BR112014009030A BR112014009030A BR112014009030A2 BR 112014009030 A2 BR112014009030 A2 BR 112014009030A2 BR 112014009030 A BR112014009030 A BR 112014009030A BR 112014009030 A BR112014009030 A BR 112014009030A BR 112014009030 A2 BR112014009030 A2 BR 112014009030A2
Authority
BR
Brazil
Prior art keywords
antibodies
antigen binding
binding antibody
chain variable
multiple antigen
Prior art date
Application number
BR112014009030A
Other languages
English (en)
Portuguese (pt)
Inventor
Astrid C Riegler
Leonardo Borras
Roberto Sommavilla
Original Assignee
Esbatech A Novartis Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esbatech A Novartis Co Llc filed Critical Esbatech A Novartis Co Llc
Publication of BR112014009030A2 publication Critical patent/BR112014009030A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/46—Hybrid immunoglobulins
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

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  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Neurology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
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  • Diabetes (AREA)
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BR112014009030A 2011-10-20 2012-10-19 anticorpo de ligação a antígenos múltiplos estável BR112014009030A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161549482P 2011-10-20 2011-10-20
PCT/EP2012/004404 WO2013056851A2 (en) 2011-10-20 2012-10-19 Stable multiple antigen-binding antibody

Publications (1)

Publication Number Publication Date
BR112014009030A2 true BR112014009030A2 (pt) 2017-09-12

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Application Number Title Priority Date Filing Date
BR112014009030A BR112014009030A2 (pt) 2011-10-20 2012-10-19 anticorpo de ligação a antígenos múltiplos estável

Country Status (15)

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US (2) US20130101586A1 (enExample)
EP (2) EP3431495A1 (enExample)
JP (3) JP2014533239A (enExample)
KR (1) KR20140082700A (enExample)
CN (2) CN109608543A (enExample)
AR (1) AR088403A1 (enExample)
AU (1) AU2012325232B2 (enExample)
BR (1) BR112014009030A2 (enExample)
CA (1) CA2850572A1 (enExample)
ES (1) ES2687245T3 (enExample)
MX (1) MX2014004521A (enExample)
RU (2) RU2018112861A (enExample)
TW (1) TWI577696B (enExample)
UY (1) UY34404A (enExample)
WO (1) WO2013056851A2 (enExample)

Families Citing this family (46)

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Publication number Priority date Publication date Assignee Title
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