JP2014533239A - 安定な複数抗原結合抗体 - Google Patents

安定な複数抗原結合抗体 Download PDF

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Publication number
JP2014533239A
JP2014533239A JP2014536147A JP2014536147A JP2014533239A JP 2014533239 A JP2014533239 A JP 2014533239A JP 2014536147 A JP2014536147 A JP 2014536147A JP 2014536147 A JP2014536147 A JP 2014536147A JP 2014533239 A JP2014533239 A JP 2014533239A
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Prior art keywords
antigen
binding antibody
linker
aho position
chain variable
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JP2014536147A
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JP2014533239A5 (enExample
Inventor
アシュトリト ツェー． リーグラー，
アシュトリト ツェー． リーグラー，
レオナルド ボラス，
レオナルド ボラス，
ロベルト ゾマヴィラ，
ロベルト ゾマヴィラ，
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Esbatech a Novartis Co LLC
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Esbatech An Alcon Biomedical Research Unit LLC
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Publication of JP2014533239A publication Critical patent/JP2014533239A/ja
Publication of JP2014533239A5 publication Critical patent/JP2014533239A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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JP2014536147A 2011-10-20 2012-10-19 安定な複数抗原結合抗体 Withdrawn JP2014533239A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161549482P 2011-10-20 2011-10-20
US61/549,482 2011-10-20
PCT/EP2012/004404 WO2013056851A2 (en) 2011-10-20 2012-10-19 Stable multiple antigen-binding antibody

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2017084447A Division JP2017125066A (ja) 2011-10-20 2017-04-21 安定な複数抗原結合抗体
JP2019067016A Division JP2019104759A (ja) 2011-10-20 2019-03-29 安定な複数抗原結合抗体

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JP2014533239A true JP2014533239A (ja) 2014-12-11
JP2014533239A5 JP2014533239A5 (enExample) 2015-08-06

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