CN1066144C - 7－羟基塔三烷的制备方法 - Google Patents

7－羟基塔三烷的制备方法 Download PDF

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Publication number
CN1066144C
CN1066144C CN95192428A CN95192428A CN1066144C CN 1066144 C CN1066144 C CN 1066144C CN 95192428 A CN95192428 A CN 95192428A CN 95192428 A CN95192428 A CN 95192428A CN 1066144 C CN1066144 C CN 1066144C
Authority
CN
China
Prior art keywords
carbon atom
group
expression
phenyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN95192428A
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English (en)
Chinese (zh)
Other versions
CN1145070A (zh
Inventor
J·P·巴斯塔特
J·D·伯尔萨特
A·克莫颂
J·P·莱康特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of CN1145070A publication Critical patent/CN1145070A/zh
Application granted granted Critical
Publication of CN1066144C publication Critical patent/CN1066144C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CN95192428A 1994-04-05 1995-04-03 7－羟基塔三烷的制备方法 Expired - Fee Related CN1066144C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9403980A FR2718135B1 (fr) 1994-04-05 1994-04-05 Procédé de préparation d'hydroxy-7 taxanes.
FR94/03980 1994-04-05

Publications (2)

Publication Number Publication Date
CN1145070A CN1145070A (zh) 1997-03-12
CN1066144C true CN1066144C (zh) 2001-05-23

Family

ID=9461748

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95192428A Expired - Fee Related CN1066144C (zh) 1994-04-05 1995-04-03 7－羟基塔三烷的制备方法

Country Status (31)

Country Link
US (1) US5750738A (enExample)
EP (1) EP0754181B1 (enExample)
JP (1) JPH09511245A (enExample)
KR (1) KR970702269A (enExample)
CN (1) CN1066144C (enExample)
AT (1) ATE168109T1 (enExample)
AU (1) AU691916B2 (enExample)
BG (1) BG62731B1 (enExample)
BR (1) BR9507443A (enExample)
CA (1) CA2186917A1 (enExample)
CZ (1) CZ284725B6 (enExample)
DE (1) DE69503366T2 (enExample)
DK (1) DK0754181T3 (enExample)
EE (1) EE03239B1 (enExample)
ES (1) ES2118592T3 (enExample)
FI (1) FI964002A7 (enExample)
FR (1) FR2718135B1 (enExample)
GE (1) GEP19991535B (enExample)
HU (1) HU214157B (enExample)
LT (1) LT4186B (enExample)
LV (1) LV11685B (enExample)
NO (1) NO314145B1 (enExample)
NZ (1) NZ284491A (enExample)
PL (1) PL316589A1 (enExample)
RO (1) RO115727B1 (enExample)
RU (1) RU2127730C1 (enExample)
SK (1) SK281075B6 (enExample)
TW (1) TW285669B (enExample)
UA (1) UA45332C2 (enExample)
WO (1) WO1995026961A1 (enExample)
ZA (1) ZA952732B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732968B1 (fr) * 1995-04-14 1997-05-16 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2750989B1 (fr) * 1996-07-09 1998-09-25 Rhone Poulenc Rorer Sa Procede de monoacylation d'hydroxy taxanes
KR100648125B1 (ko) * 1999-05-17 2006-11-24 브리스톨-마이어스스퀴브컴파니 파클리탁셀 (탁솔 (Ｔａｘｏｌ, 등록상표)) 및 파클리탁셀유사체 제조에서 실릴 에테르의 절단을 위한 신규 반응조건
JP4776843B2 (ja) 1999-10-01 2011-09-21 イムノゲン インコーポレーティッド 免疫複合体及び化学療法剤を用いる癌治療用組成物及び方法
EP2719708B1 (en) 2009-11-13 2017-10-25 Daiichi Sankyo Europe GmbH Material and methods for treating or preventing HER-3 associated diseases
EP2601220A2 (en) 2010-08-06 2013-06-12 U3 Pharma GmbH Use of her3 binding agents in prostate treatment

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0336840A1 (fr) * 1988-04-06 1989-10-11 Centre National De La Recherche Scientifique (Cnrs) Procédé de préparation du taxol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0336840A1 (fr) * 1988-04-06 1989-10-11 Centre National De La Recherche Scientifique (Cnrs) Procédé de préparation du taxol

Also Published As

Publication number Publication date
UA45332C2 (uk) 2002-04-15
AU691916B2 (en) 1998-05-28
MX9604465A (es) 1997-07-31
RU2127730C1 (ru) 1999-03-20
EP0754181A1 (fr) 1997-01-22
FR2718135B1 (fr) 1996-04-26
DE69503366T2 (de) 1999-01-21
LT4186B (en) 1997-07-25
NZ284491A (en) 1998-01-26
SK126496A3 (en) 1997-05-07
LV11685A (lv) 1997-02-20
DE69503366D1 (de) 1998-08-13
FI964002A0 (fi) 1996-10-04
CN1145070A (zh) 1997-03-12
BG100887A (en) 1998-01-30
HU214157B (hu) 1998-01-28
FR2718135A1 (fr) 1995-10-06
CZ284725B6 (cs) 1999-02-17
SK281075B6 (sk) 2000-11-07
LT96138A (en) 1997-02-25
ES2118592T3 (es) 1998-09-16
NO964104L (no) 1996-09-27
PL316589A1 (en) 1997-01-20
KR970702269A (ko) 1997-05-13
GEP19991535B (en) 1999-03-05
NO314145B1 (no) 2003-02-03
AU2309795A (en) 1995-10-23
CZ289996A3 (en) 1997-01-15
BR9507443A (pt) 1997-09-16
RO115727B1 (ro) 2000-05-30
FI964002A7 (fi) 1996-10-04
HU9602736D0 (en) 1996-11-28
TW285669B (enExample) 1996-09-11
EE03239B1 (et) 1999-12-15
NO964104D0 (no) 1996-09-27
JPH09511245A (ja) 1997-11-11
HUT75690A (en) 1997-05-28
EP0754181B1 (fr) 1998-07-08
US5750738A (en) 1998-05-12
ZA952732B (en) 1996-01-09
ATE168109T1 (de) 1998-07-15
WO1995026961A1 (fr) 1995-10-12
BG62731B1 (bg) 2000-06-30
LV11685B (en) 1997-06-20
DK0754181T3 (da) 1998-11-16
CA2186917A1 (fr) 1995-10-12

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SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee