CN106414721A - 改良的重编程方法和细胞培养平台 - Google Patents

改良的重编程方法和细胞培养平台 Download PDF

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Publication number
CN106414721A
CN106414721A CN201580019490.2A CN201580019490A CN106414721A CN 106414721 A CN106414721 A CN 106414721A CN 201580019490 A CN201580019490 A CN 201580019490A CN 106414721 A CN106414721 A CN 106414721A
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polypeptide
cells
pluripotent
inhibitor
pluripotent cells
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Chinese (zh)
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巴赫拉姆·瓦拉迈赫尔
彼得·弗林
拉姆泽伊·阿布贾卢尔
梅根·罗宾逊
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Fate Therapeutics Inc
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Fate Therapeutics Inc
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Priority to CN202510672919.3A priority Critical patent/CN120536340A/zh
Priority to CN202510673045.3A priority patent/CN120536341A/zh
Publication of CN106414721A publication Critical patent/CN106414721A/zh
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CN201580019490.2A 2014-03-04 2015-03-04 改良的重编程方法和细胞培养平台 Pending CN106414721A (zh)

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CN202510672919.3A CN120536340A (zh) 2014-03-04 2015-03-04 改良的重编程方法和细胞培养平台
CN202510673045.3A CN120536341A (zh) 2014-03-04 2015-03-04 改良的重编程方法和细胞培养平台

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US201461947979P 2014-03-04 2014-03-04
US61/947,979 2014-03-04
PCT/US2015/018801 WO2015134652A1 (en) 2014-03-04 2015-03-04 Improved reprogramming methods and cell culture platforms

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CN202510672919.3A Division CN120536340A (zh) 2014-03-04 2015-03-04 改良的重编程方法和细胞培养平台

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EP (4) EP3114214B1 (enExample)
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CN108778299A (zh) * 2016-01-12 2018-11-09 隆萨沃克斯维尔股份有限公司 生成无载体诱导多能干细胞的载体和方法
CN109679918A (zh) * 2018-12-25 2019-04-26 合肥中科干细胞再生医学有限公司 一种便捷的人诱导性多能干细胞的制备方法
CN110564673A (zh) * 2019-09-26 2019-12-13 广东工业大学 一种干细胞培养液及其应用
CN111278967A (zh) * 2017-10-11 2020-06-12 菲特治疗公司 使用时序性和瞬时质粒载体表达系统进行细胞重编程
CN114901803A (zh) * 2019-12-11 2022-08-12 修复股份有限公司 在生物反应器中悬浮扩增干细胞
WO2024078119A1 (en) * 2022-10-12 2024-04-18 Peking University Methods for chemical reprogramming and pluripotent stem cells
CN118979011A (zh) * 2024-10-22 2024-11-19 杭州瑞普晨创科技有限公司 人多能干细胞单细胞的建系方法
WO2025152036A1 (en) * 2024-01-16 2025-07-24 Chiou Guang Yuh System and method for increasing the transduction capability and reprogramming efficiency in targeting cells and tissues

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KR20240091064A (ko) * 2014-03-04 2024-06-21 페이트 세러퓨틱스, 인코포레이티드 개선된 재프로그래밍 방법 및 세포 배양 플랫폼
US10023879B2 (en) * 2014-06-04 2018-07-17 Fate Therapeutics, Inc. Minimal volume reprogramming of mononuclear cells
SG10202101358XA (en) 2015-01-26 2021-03-30 Fate Therapeutics Inc Methods and compositions for inducing hematopoietic cell differentiation
RU2018106515A (ru) 2015-07-21 2019-08-21 Зе Чилдрен'С Медикал Сентер Корпорейшн Pd-l1-экспрессирующие гемопоэтические стволовые клетки и применения
US11441126B2 (en) * 2015-10-16 2022-09-13 Fate Therapeutics, Inc. Platform for the induction and maintenance of ground state pluripotency
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CN110114470A (zh) * 2016-12-27 2019-08-09 住友化学株式会社 诱导的多能性干细胞的评价方法及选择方法、以及诱导的多能性干细胞的制备方法
CN106754729B (zh) * 2016-12-31 2020-03-17 内蒙古赛科星家畜种业与繁育生物技术研究院有限公司 利用Xist Tale抑制性转录因子制备诱导性多能干细胞的方法
US11879137B2 (en) 2017-09-22 2024-01-23 The Children's Medical Center Corporation Treatment of type 1 diabetes and autoimmune diseases or disorders
KR102791660B1 (ko) 2017-12-22 2025-04-08 페이트 세러퓨틱스, 인코포레이티드 향상된 면역 효과기 세포 및 이의 용도
WO2019133714A1 (en) * 2017-12-28 2019-07-04 The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone Generation of induced pluripotent cells by crispr activation
WO2019180247A1 (en) * 2018-03-22 2019-09-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for reprogramming somatic cells
BR112021010331A2 (pt) 2018-12-02 2021-10-05 Fate Therapeutics, Inc. Imunoterapias com o uso de células efetoras derivadas de ipsc intensificadas
WO2020203712A1 (ja) * 2019-03-29 2020-10-08 富士フイルム株式会社 特定細胞に分化する能力を有する多能性幹細胞の製造方法およびその応用
MX2022015863A (es) 2020-06-19 2023-03-23 Fate Therapeutics Inc Combinación de tipos de células efectoras derivadas de células madre pluripotentes inducidas (ipsc) para uso en inmunoterapia.
KR20230026433A (ko) * 2020-06-22 2023-02-24 라이프 테크놀로지스 코포레이션 전분화능 세포 현탁액을 배양하기 위한 방법 및 조성물
CN116348592A (zh) * 2020-10-02 2023-06-27 菲特治疗公司 诱导性多能干细胞的改善的重编程、维持和保存
US20230302044A1 (en) * 2022-03-28 2023-09-28 Steve Reilly Composition to increase cellularlongevity
IL316101A (en) 2022-04-08 2024-12-01 Fate Therapeutics Inc Skeletal cells refer to solid tumors and their use
KR20250004622A (ko) 2022-04-08 2025-01-08 페이트 세러퓨틱스, 인코포레이티드 종양 표적화를 위한 키메라 항원 수용체
WO2025208002A1 (en) * 2024-03-28 2025-10-02 Altos Labs, Inc. Targeted expression of regeneration factors in aged/senescent cells

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