CN105063208B - 一种血浆中游离的目标dna低频突变富集测序方法 - Google Patents
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Abstract
Description
基因名称 | RS号 | 检测碱基 | 基因名称 | RS号 | 检测碱基 |
XPC | rs2228001 | GT | MTHFR | rs1801133 | AA |
TP53 | rs1042522 | CC | CBR3 | rs1056892 | GG |
XRCC1 | rs25487 | CC | MTHFR | rs1801133 | AA |
GSTP1 | rs1695 | AG | ATIC | rs4673993 | TT |
ERCC1 | rs11615 | GG | MTRR | rs1801394 | AA |
ERCC1 | rs3212986 | CC | TP53 | rs1042522 | CC |
MTHFR | rs1801133 | AA | DPYD | rs3918290 | CC |
SOD2 | rs4880 | AA | DPYD | rs67376798 | TT |
GSTP1 | rs1695 | AG | TPMT | rs1800460 | CC |
MTHFR | rs1801133 | AA | TPMT | rs1800462 | CC |
MTHFR | rs1801131 | TT | TPMT | rs1800584 | CC |
GSTP1 | rs1695 | AG | UGT1A1 | rs8175347 | 7TA/7TA |
UMPS | rs1801019 | GG |
ABL1 | CBLB | DOT1L | FGF7 | IGF2 | MSH2 | PIK3CB | SDHB | TRAF7 |
ABL2 | CBR1 | DUSP6 | FGFR1 | IKBKB | MSH3 | PIK3CG | SDHC | TSC1 |
ACVR1B | CCND1 | EDNRA | FGFR2 | IKBKE | MSH4 | PIK3R1 | SDHD | TSC2 |
ACVR2A | CCND2 | EGFR | FGFR3 | IKZF1 | MSH5 | PIK3R2 | SEMA3A | TSHR |
AJUBA | CCND3 | EGR3 | FGFR4 | IL7R | MSH6 | PLK1 | SEMA3E | TSHZ2 |
AKT1 | CCNE1 | EIF4A2 | FLCN | INHBA | MSR1 | PML | SETBP1 | TSHZ3 |
AKT2 | CD79A | ELAC2 | FLT1 | IRF4 | MTOR | PMS1 | SETD2 | TUBA1A |
AKT3 | CD79B | ELF3 | FLT3 | IRS2 | MUC1 | PMS2 | SF1 | TUBB |
ALK | CDC25C | EML4 | FLT4 | ITGB2 | MUTYH | PNRC1 | SF3B1 | TUBD1 |
ANGPT1 | CDC42 | EP300 | FNTA | JAK1 | MYC | POLQ | SH2B3 | TUBE1 |
ANGPT2 | CDC73 | EPHA2 | FOXA1 | JAK2 | MYCL1 | PPP2R1A | SIN3A | TUBG1 |
APC | CDH1 | EPHA3 | FOXA2 | JAK3 | MYCN | PRDM1 | SLAMF7 | TYR |
AR | CDK12 | EPHA5 | FOXL2 | JUN | NAV3 | PRKCA | SLC4A1 | VEGFA |
ARAF | CDK2 | EPHB1 | FPGS | KDR | NBN | PRKCB | SLIT2 | VEGFB |
ARFRP1 | CDK4 | EPHB2 | FUBP1 | KEAP1 | NCOA1 | PRKCG | SMAD2 | VEZF1 |
ARID1A | CDK6 | EPHB6 | FYN | KIF1B | NCOA2 | PRKDC | SMAD3 | VHL |
ARID1B | CDK8 | EPPK1 | GAB2 | KIF5B | NCOR1 | PRSS8 | SMAD4 | WISP3 |
ASXL1 | CDKN1A | ERBB2 | GATA1 | KIT | NEK11 | PSMB1 | SMARCA1 | WT1 |
ATM | CDKN1B | ERBB3 | GATA2 | KLF4 | NF1 | PSMB2 | SMC1A | WWP1 |
ATR | CDKN2A | ERBB4 | GATA3 | KLHL6 | NF2 | PSMB5 | SMC3 | XIAP |
ATRX | CDKN2B | ERCC2 | GID4 | KRAS | NOTCH1 | PTCH1 | SMO | XPA |
AURKA | CDKN2C | ERCC3 | GNA11 | LCK | NOTCH2 | PTCH2 | SOCS1 | XPC |
AURKB | CDX2 | ERG | GNA13 | LIMK1 | NOTCH3 | PTEN | SOX2 | XPO1 |
AXIN1 | CEBPA | ESR1 | GNAQ | LRRK2 | NOTCH4 | PTP4A3 | SOX9 | XRCC3 |
AXIN2 | CFLAR | ETV1 | GNAS | MALAT1 | NPM1 | PTPN11 | SPEN | YES1 |
AXL | CHD1 | ETV6 | GNRHR | MAP2K1 | NR3C1 | PTPRD | SPRY4 | ZNF217 |
BACH1 | CHD2 | EWSR1 | GPR124 | MAP2K2 | NRAS | RAC1 | SRC | ZRSR2 |
BAK1 | CHD4 | EXT1 | GRIN2A | MAP2K4 | NSD1 | RAC2 | SRD5A2 | |
BAP1 | CHEK1 | EXT2 | GRM3 | MAP3K1 | NTRK1 | RAD21 | SRSF2 | |
BARD1 | CHEK2 | EZH2 | GSK3B | MAP3K13 | NTRK2 | RAD50 | SSTR2 | |
BCL2 | CHUK | FAM46C | H3F3A | MAPK1 | NTRK3 | RAD51 | STAG2 | |
BCL2A1 | CIC | FANCA | H3F3C | MAPK3 | NUP93 | RAF1 | STAT4 | |
BCL2L1 | CRBN | FANCC | HCK | MAPK8 | PAK3 | RARA | STAT5B | |
BCL2L2 | CREBBP | FANCD2 | HDAC1 | MAX | PAK7 | RARB | STK11 | |
BCL6 | CRIPAK | FANCE | HDAC2 | MC1R | PALB2 | RARG | SUFU | |
BCOR | CRKL | FANCF | HDAC3 | MCL1 | PARP1 | RB1 | SUZ12 | |
BCORL1 | CRLF2 | FANCG | HDAC4 | MDM2 | PARP2 | REL | SYK | |
BCR | CTCF | FANCI | HDAC6 | MDM4 | PARP3 | RET | TAF1 | |
BLM | CTLA4 | FANCL | HDAC8 | MED12 | PARP4 | RHEB | TBX3 | |
BMPR1A | CTNNA1 | FANCM | HGF | MEF2B | PCM1 | RNF43 | TEK | |
BRAF | CTNNB1 | FAT3 | HIF1A | MEN1 | PDGFRA | ROBO1 | TERT | |
BRCA1 | CUL4A | FBXW7 | HNF1A | MET | PDGFRB | ROBO2 | TET2 | |
BRCA2 | CUL4B | FCGR2A | HRAS | MITF | PDK1 | ROS1 | TFG |
BRIP1 | CYLD | FCGR2B | HRH2 | MLH1 | PHF6 | RPA1 | TGFBR2 | |
BTG1 | DAXX | FCGR2C | IDH1 | MLH3 | PIGF | RPL5 | TIPARP | |
BTK | DDR1 | FCGR3A | IDH2 | MLL | PIK3C2A | RPS14 | TLR4 | |
CARD11 | DDR2 | FCGR3B | IFNAR1 | MLL2 | PIK3C2B | RXRA | top1 | |
CASP8 | DIS3 | FGF3 | IFNAR2 | MLL3 | PIK3C2G | RXRB | top2A | |
CBFB | DNMT1 | FGF4 | IGF1 | MLL4 | PIK3C3 | RXRG | top2B | |
CBL | DNMT3A | FGF6 | IGF1R | MS4A1 | PIK3CA | SDHAF2 | TP53 |
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US15/751,722 US11001837B2 (en) | 2015-08-10 | 2016-02-18 | Low-frequency mutations enrichment sequencing method for free target DNA in plasma |
PCT/CN2016/074058 WO2017024784A1 (zh) | 2015-08-10 | 2016-02-18 | 一种血浆中游离的目标dna低频突变富集测序方法 |
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