CN104622779A - Antiageing and repairing polypeptide facial mask essence and preparation method thereof - Google Patents

Antiageing and repairing polypeptide facial mask essence and preparation method thereof Download PDF

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Publication number
CN104622779A
CN104622779A CN201510009980.6A CN201510009980A CN104622779A CN 104622779 A CN104622779 A CN 104622779A CN 201510009980 A CN201510009980 A CN 201510009980A CN 104622779 A CN104622779 A CN 104622779A
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China
Prior art keywords
facial mask
mask essence
emulsifying pot
defying age
skin
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CN201510009980.6A
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Chinese (zh)
Inventor
谢淑春
杨凯
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SHANGHAI SHENGJIE COSMETIC Co Ltd
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SHANGHAI SHENGJIE COSMETIC Co Ltd
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Priority to CN201510009980.6A priority Critical patent/CN104622779A/en
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Abstract

The invention discloses an antiageing and repairing polypeptide facial mask essence. The polypeptide facial mask essence contains the following seven active components of peptides: dipeptide diaminobutyryl benzylamide diacetate, palmitoyl tripeptide-5, palmitoyl tetrapeptide-7, pentapeptide-3, hexapeptide-11, heptapeptide-6, acetyl octapeptide-3. The polypeptide facial mask essence disclosed by the invention has the functions of effectively lifting the facial contour, resisting facial wrinkles, restoring the firmness and elasticity of the facial skin, making the facial skin be smooth and delicate and changing the state of the facial skin on the whole. The invention further discloses a preparation method of the antiageing and repairing polypeptide facial mask essence.

Description

A kind of many victory peptide defying age repair facial mask essence and preparation method thereof
Technical field
The invention belongs to cosmetic field, relate to a kind of facial mask essence, especially relate to a kind of many victory peptide defying age and repair facial mask essence and preparation method thereof.
Background technology
Perpetual youth is everyone dream, usual people it is generally acknowledged the first microgroove later just needing for 25 years old to occur defying age, but it is along with the life style of modern, the change of dietary habit and increasingly serious ambient pressure cause people to start more early to recognize antidotal importance, also more and more higher to the requirement of anti-aging product.
The outward manifestation of skin aging has microgroove usually, lack flexibility and occur relaxing, dry matt, the colour of skin is obscure, pigmentation is uneven.General anti-aging product is all mainly single for old and feeble produced problem, often effect not obvious.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, innovative usage seven kinds victory peptide components, for the different mechanism of aging, provide a kind of many victory peptide defying age containing forward position biotechnology and repair facial mask essence, comprehensive slow down aging, the effect of Evening Primerose Oil, evenly bright color, allows skin regain to compact fine and smooth, take leave of dim mute coarse, allow skin recover health status as youth.
Another object of the present invention is to provide the preparation method that a kind of above-mentioned many victory peptide defying age repair facial mask essence.
A kind of technical scheme realizing above-mentioned purpose is: a kind of many victory peptide defying age repair facial mask essence, comprise the component of following percentage by weight:
The percentage by weight sum of above-mentioned all components is 100%.
Above-mentioned one wins peptide defying age more and repairs facial mask essence, and wherein, described antiseptic adopts Mi crocare MTI, and described Mi crocare MTI is the compound of Methylisothiazolinone and iodine propilolic alcohol butyl mephenesin Carbamate.
Above-mentioned raw materials is commercially available prod.
The preparation method additionally providing a kind of many victory peptide defying age reparation facial mask essence of the present invention, comprises the following steps:
A, take deionized water in emulsifying pot, drop into load weighted EDETATE SODIUM, butanediol, glycyrrhizic acid dipotassium successively, after unlatching stirring and dissolving is even, drop into hyaluronate sodium and carbomer successively, turn on agitator and homogenizer, be warming up to 80 DEG C, and remain on 80 DEG C of stirrings 20 minutes, the component in emulsifying pot is thoroughly uniformly dispersed;
B, open cooling, after greenhouse cooling to 60 in emulsifying pot DEG C, aminomethyl propanol is dropped in emulsifying pot with after a small amount of deionized water dilution, and stirs;
C, continuation cooling, when the temperature in emulsifying pot is down to less than 50 DEG C, drop into Lubrajel Oil, the molten born of the same parents' thing of yeast, dipeptides diaminobutyryl benzyl amide diacetin, palmityl tripeptides-5, Palmitoyl Tetrapeptide-7, pentapeptide-3, six peptides-11, seven peptides-6, acetyl group octapeptide-3 and myristyl aminobutyryl valyl amido butanoic acid urea trifluoroacetate, and stir;
D, continuation are stirred and cooling, when the temperature in emulsifying pot is down to 45 DEG C, drop into Cremophor RH40, essence, antiseptic and methyl hydroxybenzoate, stir;
E, continuation cooling, when the temperature in emulsifying pot is down to 35 DEG C, discharging after inspection.
Above-mentioned many victory peptide defying age repairs the preparation method of facial mask essence, wherein, in step D, described antiseptic adopts described antiseptic to adopt Mi crocare MTI, and described Mi crocare MTI is the compound of Methylisothiazolinone and iodine propilolic alcohol butyl mephenesin Carbamate.
Have employed the technical scheme that a kind of many victory peptide defying age of the present invention repair facial mask essence, compared with prior art, many victory peptide defying age of the present invention are repaired facial mask essence and are combined forward position biotechnology technology, according to the antidotal different mechanism of action, add seven kinds of victory peptide active component respectively, be respectively dipeptides diaminobutyryl benzyl amide diacetin, palmityl tripeptides-5, Palmitoyl Tetrapeptide-7, pentapeptide-3, six peptides-11, seven peptides-6 and acetyl group octapeptide-3, these seven kinds victory peptide active component promote collagen protein and elastin laminin synthesis, reduce collagen degradation, smooth microgroove, acceleration skin cell grows, and suppresses oxygen-derived free radicals and hydroxyl radical free radical, block nerves is transmitted, and reduces expression crenulation stricture of vagina, powerful antioxidant, suppresses photoaging, repair impaired skin, rebuild epidermal structure, compact skin, reduce inflammatory reaction, long-actingly to releive, stimulate hyaluronic synthesis in body, endogenous moisturizing, makes skin full.The yeast activity thing added in addition, can active cell energy, promotes skin cell metabolism, bright color.Experimental data shows, many victory peptide defying age of the present invention are repaired facial mask essence and can effectively be promoted face skin profile, and antagonism microgroove, recovers to compact elasticity, delicate soft and smooth, changes skin of face state on the whole.
A kind of many victory peptide defying age of the present invention are adopted to repair the technical scheme of the preparation method of facial mask essence; the effectiveness of the molten born of the same parents' thing of yeast, dipeptides diaminobutyryl benzyl amide diacetin, palmityl tripeptides-5, Palmitoyl Tetrapeptide-7, pentapeptide-3, six peptides-11, seven peptides-6, acetyl group octapeptide-3 and myristyl aminobutyryl valyl amido butanoic acid urea trifluoroacetate isoreactivity composition can better be kept, promote the defying age repairing effect that many victory peptide defying age repair facial mask essence.
Detailed description of the invention
The present inventor, in order to understand technical scheme of the present invention better, is described in detail below by embodiment particularly:
Table 1
Many victory peptide defying age reparation facial mask essence of embodiment 1-3 and the facial mask essence of reference examples is prepared according to the proportioning raw materials of table 1.
Many victory peptide defying age provided by the invention are repaired facial mask essence and are prepared by following steps:
A, take deionized water in emulsifying pot, drop into load weighted EDETATE SODIUM, butanediol, glycyrrhizic acid dipotassium successively, after unlatching stirring and dissolving is even, drop into hyaluronate sodium and carbomer successively, turn on agitator and homogenizer, be warming up to 80 DEG C, and remain on 80 DEG C of stirrings 20 minutes, the component in emulsifying pot is thoroughly uniformly dispersed;
B, open cooling, after greenhouse cooling to 60 in emulsifying pot DEG C, aminomethyl propanol is dropped in emulsifying pot with after a small amount of deionized water dilution, and stirs;
C, continuation cooling, when the temperature in emulsifying pot is down to less than 50 DEG C, drop into Lubrajel Oil, the molten born of the same parents' thing of yeast, dipeptides diaminobutyryl benzyl amide diacetin, palmityl tripeptides-5, Palmitoyl Tetrapeptide-7, pentapeptide-3, six peptides-11, seven peptides-6, acetyl group octapeptide-3 and myristyl aminobutyryl valyl amido butanoic acid urea trifluoroacetate, and stir;
D, continuation are stirred and cooling, when the temperature in emulsifying pot is down to 45 DEG C, drop into Cremophor RH40, essence, antiseptic Mi crocare MTI and methyl hydroxybenzoate, stir;
E, continuation cooling, when the temperature in emulsifying pot is down to 35 DEG C, discharging after inspection.
Many victory peptide defying age of the present invention are repaired in facial mask essence, and dipeptides diaminobutyryl benzyl amide diacetin can suppress acetylcholinergic receptor to discharge, level and smooth pseudo wrinkle; Palmityl tripeptides-5 can be simulated human activin tissue growth factor TGF-β and be repaired impaired skin and hyaluronic acid synthesis; Palmitoyl Tetrapeptide-7 can improve skin microcirculation, diminishes inflammation, free radical and oxidation reaction, promotes collagen protein synthesis; Pentapeptide-3 can simulate the external natural mechanism of enkephalin, reduces histrionic muscles and shrinks, and suppresses wrinkle to be formed; Six peptides-11 can cell-cell adhesion effect, and prevent skin from relaxing, even skin tone, improves dim mute; Seven peptides-6 can improve deacetylation enzymatic activity, and DNA plerosis is damaged, and extend the fibroblast life-span; Acetyl group octapeptide-3 can block nerves transmission, reduces expression stricture of vagina, wrinkle.Defying age containing these seven kinds victory peptides repairs facial mask essence, has obvious defying age repair function.
Facial mask essence, the facial mask essence of reference examples and the effect of commercially available anti-ageing face mask are repaired to many victory peptide defying age of the above-mentioned embodiment 1-3 prepared and carries out assessment contrast respectively.
Choose the female volunteers in 75 25-28 years, be divided into five groups, often organize 15 people, these five groups use many victory peptide defying age containing embodiment 1-3 to repair the facial film of facial mask essence, the facial film of the facial mask essence containing reference examples and commercially available anti-ageing face mask correspondingly, frequency of utilization is use three times every other day weekly, each deposited 15 minutes, continue use 8 weeks.Respectively canthus wrinkle, skin elasticity are carried out test and observed, and carry out questionnaire assessment by volunteer, comprehensively obtain data.Test result is as follows:
The test result of canthus wrinkle is as shown in table 2, and in table 2, A represents that canthus wrinkle obviously reduces; B represents that canthus wrinkle reduces; C represents canthus wrinkle indistinction; D represents that canthus wrinkle increases to some extent; E represents that canthus wrinkle obviously increases.
Table 2
From the canthus wrinkle result of human volunteer's test, experimenter effectively can reduce canthus wrinkle after 8 weeks substantially employing the embodiment product that with the addition of seven kinds of anti-aging beauty-cares victory peptides, skin has sense of compacting, and the reference examples of not adding victory peptide contrasted therewith and commercially available anti-ageing face mask, more people after a procedure sensory effect are not clearly.
The test result of skin elasticity is as shown in table 3, and in table 3, A represents that skin elasticity is obviously improved; B represents that skin elasticity is improved; C represents skin elasticity indistinction; D represents that skin elasticity is deteriorated to some extent; E represents that skin elasticity is deteriorated.
Table 3
Utilization facial film is carrier, be added with the defying age essence of seven kinds of victory peptides more easily by percutaneous absorption, deep layer is nourished, help and prevent skin hydropenia aging, improve skin dark yellow, make skin recover young elasticity, continue to use and can reduce the pale beautiful colour of skin, alleviate microgroove to produce, make the young vigor of skin, glittering and translucent.From the skin elasticity result of experimenter human test, the skin of face elasticity of experimenter is significantly improved, full soft and smooth.Commercially available anti-ageing face mask and reference examples much inferior by contrast to skin elasticity castering action.
As can be seen here, many victory peptide defying age of the present invention are repaired facial mask essence and be with the addition of seven kinds of beauty treatment victory peptide active component: dipeptides diaminobutyryl benzyl amide diacetin, palmityl tripeptides-5, Palmitoyl Tetrapeptide-7, pentapeptide-3, six peptides-11, seven peptides-6, acetyl group octapeptide-3, utilize different victory peptide active component, effectively can promote collagen protein and elastin laminin synthesis; The activity of protease inhibition, reduces collagen degradation; Controlled oxidization reacts, scavenging free radicals; The wrinkle that minimizing nerve conduction produces undue muscular movement and formed; Reparation damaged dna damages, and rebuilds skin texture; Reduce inflammatory reaction, calm skin of releiving; Supplement moisture of skin, go down microgroove and coarse, thus make skin return to youth, compact, be rich in gloss and elastic health status.
Those of ordinary skill in the art will be appreciated that, above embodiment is only used to the present invention is described, and be not used as limitation of the invention, as long as in spirit of the present invention, all will drop in Claims scope of the present invention the change of the above embodiment, modification.

Claims (4)

1. win peptide defying age more and repair a facial mask essence, it is characterized in that, comprise the component of following percentage by weight:
The percentage by weight sum of above-mentioned all components is 100%.
2. a kind of many victory peptide defying age as claimed in claim 1 repair facial mask essence, and it is characterized in that, described antiseptic adopts Microcare MTI, and described Microcare MTI is the compound of Methylisothiazolinone and iodine propilolic alcohol butyl mephenesin Carbamate.
3. many victory peptide defying age as claimed in claim 1 repair a preparation method for facial mask essence, it is characterized in that, comprise the following steps:
A, take deionized water in emulsifying pot, drop into load weighted EDETATE SODIUM, butanediol, glycyrrhizic acid dipotassium successively, after unlatching stirring and dissolving is even, drop into hyaluronate sodium and carbomer successively, turn on agitator and homogenizer, be warming up to 80 DEG C, and remain on 80 DEG C of stirrings 20 minutes, the component in emulsifying pot is thoroughly uniformly dispersed;
B, open cooling, after greenhouse cooling to 60 in emulsifying pot DEG C, aminomethyl propanol is dropped in emulsifying pot with after a small amount of deionized water dilution, and stirs;
C, continuation cooling, when the temperature in emulsifying pot is down to less than 50 DEG C, drop into Lubrajel Oil, the molten born of the same parents' thing of yeast, dipeptides diaminobutyryl benzyl amide diacetin, palmityl tripeptides-5, Palmitoyl Tetrapeptide-7, pentapeptide-3, six peptides-11, seven peptides-6, acetyl group octapeptide-3 and myristyl aminobutyryl valyl amido butanoic acid urea trifluoroacetate, and stir;
D, continuation are stirred and cooling, when the temperature in emulsifying pot is down to 45 DEG C, drop into Cremophor RH40, essence, antiseptic and methyl hydroxybenzoate, stir;
E, continuation cooling, when the temperature in emulsifying pot is down to 35 DEG C, discharging after inspection.
4. many victory peptide defying age as claimed in claim 3 repair the preparation method of facial mask essence, it is characterized in that, in step D, described antiseptic adopts described antiseptic to adopt Microcare MTI, and described Microcare MTI is the compound of Methylisothiazolinone and iodine propilolic alcohol butyl mephenesin Carbamate.
CN201510009980.6A 2015-01-08 2015-01-08 Antiageing and repairing polypeptide facial mask essence and preparation method thereof Pending CN104622779A (en)

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CN105232352A (en) * 2015-10-30 2016-01-13 中山卡丝生物科技有限公司 Polypeptide compound for removing wrinkles in eyes and preparation method of polypeptide compound
CN105878131A (en) * 2016-06-08 2016-08-24 广州市创美时美容化妆品有限公司 Anti-aging cosmetic composition with plant-cell active substances and polypeptide
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CN105232352A (en) * 2015-10-30 2016-01-13 中山卡丝生物科技有限公司 Polypeptide compound for removing wrinkles in eyes and preparation method of polypeptide compound
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US10086035B2 (en) 2016-02-04 2018-10-02 ALASTIN Skincare, Inc. Compositions and methods for invasive and non-invasive procedural skincare
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CN105878131B (en) * 2016-06-08 2019-06-11 佛山市奥姿美生物科技有限公司 A kind of anti-aging cosmetics composition containing plant cell active matter and polypeptide
CN105878131A (en) * 2016-06-08 2016-08-24 广州市创美时美容化妆品有限公司 Anti-aging cosmetic composition with plant-cell active substances and polypeptide
CN106038351B (en) * 2016-07-12 2019-07-09 深圳市维琪医药研发有限公司 It is a kind of for desalinating the peptide composition of wrinkle
CN106038351A (en) * 2016-07-12 2016-10-26 深圳市维琪医药研发有限公司 Polypeptide composition for smoothing wrinkles
CN105997828A (en) * 2016-07-22 2016-10-12 广州艾蓓生物科技有限公司 Smearing type moistening and brightening essence liquid
CN105997828B (en) * 2016-07-22 2019-02-22 广州艾蓓生物科技有限公司 Smear water light Essence
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CN107308020A (en) * 2017-07-06 2017-11-03 珠海联邦制药股份有限公司 A kind of peptide composition of stabilization and its application
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