CN107929220A - It is a kind of that there is stem cell skin care compound for repairing anti-aging function and preparation method thereof - Google Patents
It is a kind of that there is stem cell skin care compound for repairing anti-aging function and preparation method thereof Download PDFInfo
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- CN107929220A CN107929220A CN201711250576.3A CN201711250576A CN107929220A CN 107929220 A CN107929220 A CN 107929220A CN 201711250576 A CN201711250576 A CN 201711250576A CN 107929220 A CN107929220 A CN 107929220A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses a kind of stem cell skin care compound and preparation method thereof for having and repairing anti-aging function, include the component of following weight fraction：0.5~2 part of stem cell, 0.1~0.5 part of Sodium Hyaluronate, hydrolyzes 0.1~0.5 part of Scleroglucan, 0.5 part of trehalose, 3~5 parts of glycine betaine, 3~5 parts of glycerine, 0.03 part of triethanolamine, 3 parts of reed fragrant plant oil, 3 parts of 2 parts of Gatuline Expression AF, Collrepair DG.The present invention; it is combined in plant stem cell using three kinds of stem cells; it includes the Epigenetics factor effectively can provide nutrient for mankind's adult stem cell; effectively make skin epidermal stem cell, corium stem cell, subcutaneous tissue stem cell activation; skin corium can be reached; active ingredient in plant stem cell can lift the power of regeneration of skin; improve epidermis and corium from inside to outside; to protect and maintain the function of human adult stem cell; skin histology is updated reparation and slow down aging; improve skin quality, reduce the additions of other both effectiveness raw materials to reduce cost.
Description
Technical field
The present invention relates to skin care item, and in particular to a kind of to have the stem cell skin care compound and its system for repairing anti-aging function
Preparation Method.
Background technology
As social economy increases, people's level of consumption rises, the requirement lifting of demand and effect to skin care item, then
Various cosmetics and skincare product comes into being, and wherein Essence class product is very fast-selling a kind of production in these cosmetics and skincare products
Product.
Generally there is moisturizing or whitening function in view of in the streets commercially available Essence, or basis is repaired and exfoliating comes
Repair epidermal cell function.But as the age is gradually grown, Skin Cell aging, epidermal renewal is reduced, and is managed according to Hayflick boundaries
By adult tissue's stem cell division number is limited, therefore the exhaustion of stem cell limits the service life of skin histology.And skin
The continuous updating of tissue and to repair to maintaining young skin be necessary but current elite class product, painting type of not running affairs
Or facial mask formula does not all reach the effect of good.
It can be seen from the above that the problem of current skin care item presence can not realize good effects.
The content of the invention
The technical problems to be solved by the invention are the problem of current skin care item presence can not realize good effects.
In order to solve the above-mentioned technical problem, the technical solution adopted in the present invention there is provided a kind of with the anti-ageing work(of reparation
The stem cell skin care compound of energy, includes the component of following weight fraction：
5~20 parts of plant stem cell,
Polyacrylate cross-linked polymer~6 1.5 part,
1~5 part of Sodium Hyaluronate,
1~5 part of Scleroglucan is hydrolyzed,
5 parts of trehalose,
30~50 parts of glycine betaine,
30~50 parts of glycerine,
0.3 part of triethanolamine,
30 parts of reed fragrant plant oil,
20 parts of Gatuline Expression AF,
30 parts of Collrepair DG,
Wherein, the plant stem cell by apple stem cell, Morocco nut stem cell, Crithmum maritimum stem cell according to 2:1:
1 part by weight is mixed to get；The Collrepair DG are water, niacinamide, glycerine, pungent glycol, xanthans, Radix Salviae Miltiorrhizae extraction
The mixture of thing；The Gatuline ExpressionAF are the mixture of 1,3~propane diols, water and Spilanthes oleracea extract.
In another preferred embodiment, 2% card ripple 940 of 60 parts of parts by weight is further included.
In another preferred embodiment, the component of following weight fraction is further included：
68 20 parts of Septic Montanov,
15 parts of Cetyl alochol,
30 parts of 2EHP,
20 parts of GTCC.
In another preferred embodiment, 5 parts of plant stem cell, 5 parts of Sodium Hyaluronate, hydrolyzes 5 parts of Scleroglucan, sweet tea
50 parts of dish alkali, 35 parts of glycerine.
Present invention also offers a kind of preparation method for the stem cell skin care compound for having and repairing anti-aging function, including with
Lower step：
Polyacrylate cross-linked polymer~6 are first added to the water stirring by step 1, while are heated to 80~85 DEG C
Afterwards, hydrolysis Scleroglucan, Sodium Hyaluronate, 3~5min of homogeneous are added；
Step 2, sequentially adds after trehalose, glycine betaine, glycerine and reed fragrant plant oil and stirs to being completely dissolved；
Step 3, triethanolamine is added after being cooled to 60 DEG C, is stirred evenly and is further continued for cooling down；
Step 4, adds Collrepair DG, Gatuline Expression AF and stem cell when being cooled to 45 DEG C
Stir evenly.
In another preferred embodiment, in step 2, card ripple 940 is added at the same time when adding trehalose.
In another preferred embodiment, after the completion of step 2, by Septic Montanov 68, Cetyl
Alochol, 2EHP and GTCC are heated to 80 DEG C, are added after uniform stirring in the liquid phase of step 2.
In another preferred embodiment, step 5 is further included：Obtained liquid phase is filled out into 25mL into face paper.
The present invention, is combined using three kinds of stem cells in plant stem cell, it includes the Epigenetics factor can be effective
Nutrient is provided for mankind's adult stem cell, effectively makes skin epidermal stem cell, corium stem cell, subcutaneous tissue stem cell activation,
Skin corium can be reached, the active ingredient in plant stem cell can lift the power of regeneration of skin, improve epidermis and true from inside to outside
Skin, to protect and maintain the function of human adult stem cell, makes skin histology be updated reparation and slows down aging, and improves skin
Matter, reduces the additions of other both effectiveness raw materials to reduce cost.
Embodiment
The present invention provides a kind of stem cell skin care compound for having and repairing anti-aging function and preparation method thereof, tie below
Specific embodiment is closed to be described in detail the present invention.
First, a kind of stem cell skin care compound with reparation anti-aging function provided by the invention includes following weight fraction
Component：
5~20 parts of stem cell,
Polyacrylate cross-linked polymer~6 1.5 part,
1~5 part of Sodium Hyaluronate,
1~5 part of Scleroglucan is hydrolyzed,
5 parts of trehalose,
30~50 parts of glycine betaine,
30~50 parts of glycerine,
0.3 part of triethanolamine,
30 parts of reed fragrant plant oil (glycerine polymethacrylates/Gantrez AN-119/propane diols),
20 parts of Gatuline Expression AF,
30 parts of Collrepair DG.
It is as follows that the preparation process of the present invention includes step：
Polyacrylate cross-linked polymer~6 are first added to the water stirring by step 1, while are heated to 80~85 DEG C
Afterwards, hydrolysis Scleroglucan and 3~5min of Sodium Hyaluronate homogeneous are added；
Step 2, is stirred to completely molten after the water of step 1 mutually sequentially adds trehalose, glycine betaine, glycerine and reed fragrant plant oil
Start to cool down after solution；
Step 3, triethanolamine is added after being cooled to 60 DEG C, is stirred evenly and is further continued for cooling down；
Step 4, adds Collrepair DG, Gatuline Expression AF and stem cell when being cooled to 45 DEG C
Stir evenly.
The plant stem cell, safe source is with extensive, by apple stem cell, Morocco nut stem cell, Crithmum maritimum
Stem cell interworking, optimal ratio is 2:1:1, it can reach the effect of ideal.
Apple stem cell selected as Switzerland hundred happy apple stem cells of rice, apple stem cell can be effectively increased skin progenitor cell
Vigor and service life, make the vigor of epidermal stem cells is more longlasting to resist environment pressure with protection skin progenitor cell, subcutaneous tissue stem cell
The injury that power is brought, so that the effect of reaching delaying skin aging, and it is obviously improved the cell mass formation efficiency of epidermal stem cells.
Nut stem cell selected as Switzerland of Morocco hundred Morocco nut stem cells of rice, can lift dermis of skin stem cell
Power of regeneration, so as to fulfill deep layer shine skin the effect of, protection and activating human body corium stem cell active ingredient, not only help rush
Into the natural repair process of skin, skin can also be helped to resist aging from source, regain youth glossy skin.
Crithmum maritimum stem cell selected as France match Bick Crithmum maritimum stem cell, rich in a variety of lipids, phenolic compound, carbohydrate
And polyhydroxy substance, have and adjust pigmentation, moisturizing, strengthens anti-oxidation protection, adjusts cutin generation, stimulates skin healing
Effect.
Polyacrylate cross-linked polymer~6, are the emulsification stabilization agent SEPIMAX for matching BickTM ZEN。Collrepair
DG is water, niacinamide, glycerine, pungent glycol, xanthans, the Salvia root P.E that German BASF is produced, and has and reverses saccharification to make
With, recover intracellular cytoskeleton, cellular resilience improves, anti-saccharification improves the colour of skin, recover skin elasticity, can help it is dry thin
Born of the same parents' activity lifting in vivo.
Gatuline Expression AF are 1,3~propane diols, water and the Spilanthes oleracea extraction that Gattefosse praises method lion
Thing, rich in isobutyramide, it is ensured that the concentration of spilanthol, has been subjected in vitro method (nerve~muscle is planted altogether) confirmation, show immediately
And reversible muscle relaxant effect.The applicable law confirms have the activity of strong smooth skin, can quickly reduce canthus fish
Tail line, auxiliary reach anti-wrinkle effect.Gatuline Expression extract from Madagascar and the Indian Ocean to Chinese celery, gold
Toggle extract includes caprylic/capric triglyceride and Herba Cancriniae lasiocarpae (SPILANTHES ACMELLA) flower extract.
Gatuline Expression AF are the alcohol-free versions of Gatuline Expression, including 1,3- propane diols, water and thousand days
Chrysanthemum (ACMELLA OLERACEA) extract.
Wherein, plant stem cell, Sodium Hyaluronate, hydrolysis Scleroglucan, glycine betaine and glycerine have certain ratio model
Enclose, the ratio that operating personnel can adjust this 5 kinds of components according to being actually needed, be below more preferable ratio selection：
1. 5 parts of plant stem cell, 5 parts of Sodium Hyaluronate, hydrolyzes 5 parts of Scleroglucan, 50 parts of glycine betaine, 35 parts of glycerine.
2. 20 parts of plant stem cell, 1 part of Sodium Hyaluronate, hydrolyzes 1 part of Scleroglucan, 30 parts of glycine betaine, 48 parts of glycerine.
3. 16 parts of plant stem cell, 4 parts of Sodium Hyaluronate, hydrolyzes 4 parts of Scleroglucan, 46 parts of glycine betaine, 30 parts of glycerine.
4. 10 parts of plant stem cell, 3 parts of Sodium Hyaluronate, hydrolyzes 3 parts of Scleroglucan, 34 parts of glycine betaine, 50 parts of glycerine.
First, it is below other more preferred embodiments：
Embodiment one
Each component and its parts by weight are：
5~20 parts of stem cell,
Polyacrylate cross-linked polymer~6 1.5 part,
1~3 part of Sodium Hyaluronate,
1~5 part of Scleroglucan is hydrolyzed,
5 parts of trehalose,
30 parts of glycine betaine,
50 parts of glycerine,
0.3 part of triethanolamine,
30 parts of reed fragrant plant oil,
20 parts of Gatuline Expression AF,
30 parts of Collrepair DG,
2% 940 60 parts of card ripple.
The preparation process of embodiment one and former embodiment difference lies in：
(1) in step 2, card ripple 940 is added at the same time when adding trehalose；
(2) step 5 is further included：Obtained liquid phase is filled out into 25mL into face paper, assimilation effect is fast, can improve elite suction
Produce effects rate so that elite function maximizes.Stored using face paper, can be used directly as facial mask, add occupation mode, make
With more flexible.
Embodiment two
Component and its composition by weight are：
5~20 parts of stem cell,
Polyacrylate cross-linked polymer~6 1.5 part,
1~3 part of Sodium Hyaluronate,
1~5 part of Scleroglucan is hydrolyzed,
5 parts of trehalose,
30 parts of glycine betaine,
50 parts of glycerine,
0.3 part of triethanolamine,
30 parts of reed fragrant plant oil,
20 parts of Gatuline Expression AF,
30 parts of Collrepair DG,
68 20 parts of Septic Montanov,
15 parts of Cetyl alochol,
30 parts of 2EHP,
20 parts of GTCC.
Embodiment two and former embodiment difference lies in：
(1) in step 2, card ripple 940 is added at the same time when adding trehalose；After the completion of step 2, by Septic
Montanov 68, Cetyl alochol, 2EHP and GTCC are heated to 80 DEG C, are added after uniform stirring in the liquid phase of step 2.
Septic Montanov 68 are the compound of cetostearyl alcohol and cetearyl glucoside, Cetyl
Alochol is cetanol, and 2EHP is ethylhexyl palmitate, and GTCC is caprylic/capric triglyceride.These four components add
Enter, smooth feeling can be effectively increased, skin sense is comfortable, improves usage experience.
(2) step 5 is further included：Obtained liquid phase is filled out into 25mL into face paper, assimilation effect is fast, can improve elite suction
Produce effects rate so that elite function maximizes.
2nd, it is below influence experiment of the different skin-protection products to skin quality
Implementation crowd is divided into 6 groups, every group of 8 people, the tested objective packet of crowd, adopts double-blind, exclude psychological factor with
Human factor influences test result.
6 groups of subjects smear totally 8 kinds of cosmetics and skincare products 2 times of embodiment 1~3 and comparative example 1~5 respectively daily morning and evening, and one
Overall assessment is carried out after a month to product effect, it is three grades that skin quality improves resultant effect comparation and assessment with facial wrinkles, respectively
It is:Effect unobvious (0~3 point), effect is general (4~6 points), and significant effect (7~10 points), recruitment evaluation result see the table below：
As seen from the above table, the present invention in skin effect it is more superior, therefore the stem cell compound in the present invention with
These components of Collrepair DG/Gatuline Expression AF have synergistic effect, stem cell a kind of than single use
Skin care item skin quality improvement more preferably.
Compared with prior art, be combined in plant stem cell of the invention using three kinds of stem cells, it includes table
Existing gene effectively provides nutrient for mankind's adult stem cell, effectively make skin epidermal stem cell, corium stem cell, subcutaneous group
Stem cell activation is knitted, can reach skin corium, the active ingredient in plant stem cell can lift the power of regeneration of skin, from inside to outside
Improve epidermis and corium, to protect and maintain the function of human adult stem cell, be updated skin histology and repair and delay
Aging, improves skin quality, reduces the additions of other both effectiveness raw materials to reduce cost.
The present invention is not limited to above-mentioned preferred forms, and anyone should learn that the knot made under the enlightenment of the present invention
Structure changes, and the technical schemes that are same or similar to the present invention, each fall within protection scope of the present invention.
Claims (8)
1. a kind of have the stem cell skin care compound for repairing anti-aging function, it is characterised in that includes the group of following weight fraction
Point：
5~20 parts of plant stem cell,
Polyacrylate cross-linked polymer~6 1.5 part,
1~5 part of Sodium Hyaluronate,
1~5 part of Scleroglucan is hydrolyzed,
5 parts of trehalose,
30~50 parts of glycine betaine,
30~50 parts of glycerine,
0.3 part of triethanolamine,
30 parts of reed fragrant plant oil,
20 parts of Gatuline Expression AF,
30 parts of Collrepair DG,
Wherein, the plant stem cell by apple stem cell, Morocco nut stem cell, Crithmum maritimum stem cell according to 2:1:1
Part by weight is mixed to get；The Collrepair DG are water, niacinamide, glycerine, pungent glycol, xanthans, Salvia root P.E
Mixture；The Gatuline Expression AF are the mixture of 1,3~propane diols, water and Spilanthes oleracea extract.
2. a kind of stem cell skin care compound with reparation anti-aging function as claimed in claim 1, it is characterised in that also wrap
Include 2% card ripple 940 of 60 parts of parts by weight.
3. a kind of stem cell skin care compound with reparation anti-aging function as claimed in claim 1, it is characterised in that also wrap
Include the component of following weight fraction：
68 20 parts of Septic Montanov,
15 parts of Cetyl alochol,
30 parts of 2EHP,
20 parts of GTCC.
A kind of 4. stem cell skin care compound with reparation anti-aging function as claimed in claim 1, it is characterised in that plant
5 parts of stem cell, 5 parts of Sodium Hyaluronate, hydrolyzes 5 parts of Scleroglucan, 50 parts of glycine betaine, 35 parts of glycerine.
5. a kind of preparation method with the stem cell skin care compound for repairing anti-aging function as claimed in claim 1, it is special
Sign is, comprises the following steps：
Polyacrylate cross-linked polymer~6 are first added to the water stirring by step 1, while after being heated to 80~85 DEG C,
Add hydrolysis Scleroglucan, Sodium Hyaluronate, 3~5min of homogeneous；
Step 2, sequentially adds after trehalose, glycine betaine, glycerine and reed fragrant plant oil and stirs to being completely dissolved；
Step 3, triethanolamine is added after being cooled to 60 DEG C, is stirred evenly and is further continued for cooling down；
Step 4, adds Collrepair DG, Gatuline Expression AF and stem cell stirring when being cooled to 45 DEG C
Uniformly.
6. a kind of preparation method with the stem cell skin care compound for repairing anti-aging function as claimed in claim 5, it is special
Sign is, in step 2, card ripple 940 is added at the same time when adding trehalose.
7. a kind of preparation method with the stem cell skin care compound for repairing anti-aging function as claimed in claim 5, it is special
Sign is, after the completion of step 2, Septic Montanov 68, Cetyl alochol, 2EHP and GTCC are heated to 80 DEG C,
Added after uniform stirring in the liquid phase of step 2.
8. a kind of preparation method with the stem cell skin care compound for repairing anti-aging function as claimed in claim 5, it is special
Sign is, further includes step 5：Obtained liquid phase is filled out into 25mL into face paper.
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|---|---|---|---|
| CN201711250576.3A CN107929220A (en) | 2017-12-01 | 2017-12-01 | It is a kind of that there is stem cell skin care compound for repairing anti-aging function and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711250576.3A CN107929220A (en) | 2017-12-01 | 2017-12-01 | It is a kind of that there is stem cell skin care compound for repairing anti-aging function and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010195A (en) * | 2018-10-13 | 2018-12-18 | 陈洁珍 | A kind of whitening Wrinkle-and scar-removing repairs face cream and preparation method thereof |
| CN109394640A (en) * | 2018-11-12 | 2019-03-01 | 广东科玮生物技术股份有限公司 | A kind of ferment skin care compositions and its application |
| CN111888459A (en) * | 2020-08-18 | 2020-11-06 | 深圳市俊元生物科技有限公司 | Lyophilized powder containing mesenchymal stem cell secretory factor and solvent thereof |
| CN115282091A (en) * | 2021-12-08 | 2022-11-04 | 浙江东印化妆品有限公司 | Composition for resisting oxidation, sugar and light aging and application thereof |
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| CN105168068A (en) * | 2015-10-14 | 2015-12-23 | 广东三九军大生物科技有限公司 | Crithmum maritimum essence capable of removing red blood streaks |
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| CN103494723A (en) * | 2013-06-26 | 2014-01-08 | 马玉贤 | Stem cell skin care composition and manufacturing method and application thereof |
| CN103800253A (en) * | 2014-03-07 | 2014-05-21 | 澳宝化妆品（惠州）有限公司 | Moisturizing refreshing cleansing cream |
| CN104546639A (en) * | 2014-12-12 | 2015-04-29 | 黄宗堂 | Stem cell essence and preparation method thereof |
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| CN106109296A (en) * | 2016-06-30 | 2016-11-16 | 彭燕辉 | A kind of moisturizing essence lotion and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010195A (en) * | 2018-10-13 | 2018-12-18 | 陈洁珍 | A kind of whitening Wrinkle-and scar-removing repairs face cream and preparation method thereof |
| CN109394640A (en) * | 2018-11-12 | 2019-03-01 | 广东科玮生物技术股份有限公司 | A kind of ferment skin care compositions and its application |
| CN111888459A (en) * | 2020-08-18 | 2020-11-06 | 深圳市俊元生物科技有限公司 | Lyophilized powder containing mesenchymal stem cell secretory factor and solvent thereof |
| CN115282091A (en) * | 2021-12-08 | 2022-11-04 | 浙江东印化妆品有限公司 | Composition for resisting oxidation, sugar and light aging and application thereof |
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