CN108420776A - A kind of essence composition and the re-surface intensive wrinkle correct and preparation method thereof that compacts being made from it - Google Patents

A kind of essence composition and the re-surface intensive wrinkle correct and preparation method thereof that compacts being made from it Download PDF

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CN108420776A
CN108420776A CN201810577781.9A CN201810577781A CN108420776A CN 108420776 A CN108420776 A CN 108420776A CN 201810577781 A CN201810577781 A CN 201810577781A CN 108420776 A CN108420776 A CN 108420776A
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parts
weight
essence
extract
compacts
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何廷刚
耿林
杨雪芳
林云
肖令民
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Hua An Tang Biotech Group Co Ltd
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Hua An Tang Biotech Group Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of essence compositions and the re-surface intensive wrinkle correct and preparation method thereof that compacts being made from it, by weight, including following component:0.005 0.015 parts(A)Myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate;0.005 0.015 parts(B)5 0.005 0.015 parts of palmityl tripeptides;0.1 0.3 parts(C)Rhizoma Zingiberis zerumbet extract;0.05 0.25 parts(D)Rye seed extract.The present invention is by compounding the palmityl tripeptides 5 of the myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate of certain content and certain content, and it is aided with the Rhizoma Zingiberis zerumbet extract of certain content and the rye seed extract of certain content, pass through the coordinated of each component, it is prepared and resists skin ageing, reduces the good essence composition of wrinkle effect, the essence composition is added in essence matrix and obtains the re-surface intensive wrinkle correct that compacts, the essence has good moisturizing and barrier maintenance effect, skin elasticity and degree of compacting can be significantly improved simultaneously, reduce wrinkle.

Description

A kind of essence composition and the re-surface intensive wrinkle correct and preparation method thereof that compacts being made from it
Technical field
The present invention relates to cosmetic field, more particularly to a kind of essence composition and be made from it compact re-surface intensive wrinkle correct and Preparation method.
Background technology
Face skin aging is the main performance of human senescence.Everyone must face the years test, natural aging, Hereditation, sunlight irradiation etc. can all cause wrinkle lead to the problem of and the various skin such as cutis laxa is sagging.
Facial wrinkles type is usually divided into three kinds, i.e. dynamic property wrinkle, gravitation wrinkle and orthostatic wrinkle:Dynamic property Wrinkle is that mimetic muscle is shunk for a long time as a result, being mainly manifested in the fish of the forehead line of frontalis, the glabella line of superciliary corrugator muscle, orbicular muscle of eye The cheek twill etc. of tail line, the bicker line and lip vertical line of musculus orbicularis oris, greater zygomatic muscle and musculus quadratus labii superioris.Gravitation wrinkle be then by In subcutaneous tissue fat, muscle and bone atrophy, in addition what the long term of gravity gradually generated.It is mainly manifested in eyelid Position, face, jaw portion, double chin etc..Orthostatic wrinkle, that is, inherency wrinkle, when people is born, that is, existing, belong to normal physiological phenomena. But with being continuously increased for age and continuously decreasing for systemic physiological function, skin elasticity is also faded, and causes original body Position property crease lines are gradually deepened and are increased, and it is sagging relaxation occur for skin between line.
In general, start within 30 years old, there is upper and lower eyelid skin to relax, gradually cause birdeye, pouch and crow's feet;About 40 The relaxation of eyelid skin aggravates after year, and nasolabial groove is distinct, and glabella and forehead generate wrinkle and gradually aggravate;Lower jaw, neck after 50 years old Skin obviously relaxes, and nose is gradually flat;Temples cheek skin and sub-dermal structures distinctness are thinning after 60 years old, under each position skin It hangs down and wrinkle is especially distinct.
The generation of wrinkle and premature skin aging have seriously affected the self-confidence of people, while also having been brought to social activity Certain puzzlement, therefore more and more consumers start to focus on anti-ageing maintenance, especially in recent years, anti-aging concept is gradually to year Light group's infiltration has caused " anti-aging in advance " trend, and young consumers begin to use anti-aging skin care product, in this, as prevention Property measure, anti-aging product already becomes and increases the most fast maximum category of potentiality.But declare to compact on the market, is crease-resistant, being promoted, The anti-aging products such as modeling face have very much, but often the effect after use is not apparent.
Invention content
In view of this, the primary purpose of the present invention is that overcome above-mentioned the shortcomings of the prior art, one kind is provided and is resisted Skin ageing reduces the good essence composition of wrinkle effect, which is added in essence matrix obtain compacting it is anti- Wrinkle essence, which has good moisturizing and barrier maintenance effect, while can significantly improve skin elasticity and degree of compacting, and reduces Wrinkle.
The technical solution adopted by the present invention is as follows:
A kind of essence composition disclosed by the invention, by weight, including following component:
(A)0.005-0.015 parts of myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate;
(B)- 5 0.005-0.015 parts of palmityl tripeptides;
(C)0.1-0.3 parts of Rhizoma Zingiberis zerumbet extract;
(D)0.05-0.25 parts of rye seed extract.
Wherein, the component(A)With component(B)Weight ratio be 1:1-2.
Myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate of the present invention is originated from Switzerland's high-tech Micromolecule polypeptide ingredient pass through by stimulating the biosynthesis of glucosaminoglycan to increase the content of hyaluronic acid and promote core The level of heart protein glycan and Lumican carrys out strengthened collagen fiber, its two kinds of activity are perfectly combined together, and are had Effect helps to fight cutis laxa, promotes tension, elasticity and the degree of compacting of skin, and realizes that skin compacts and is remolded with profile.
Palmityl tripeptides -5 of the present invention are originated from the high-tech tripeptides small molecule of Switzerland, can promote fibrocyte The synthesis of middle collagen, while can protect the collagen under pressure state in keratinocyte, double mechanism help to disappear The smooth skin of wrinkle.
Rhizoma Zingiberis zerumbet extract of the present invention passes through supercritical CO2Technology is extracted to obtain, and contains 400-700ppm ball ginger Ketone can help the thickness for reducing adipose tissue, improve skin dynamic circulation, be woven with to extracellular basis set and protect and repair well Multiple effect.
Rye seed extract of the present invention is rich in rye arabinoxylans, can stimulate fibroblast Machinery and biological function, hence it is evident that the retractility and tension for improving skin generate lasting skin tightening effect.
It compacts re-surface intensive wrinkle correct the invention also discloses one kind, including above-mentioned essence composition.
Wherein, the re-surface intensive wrinkle correct that compacts further includes by weight essence matrix and water.
Wherein, the essence matrix, including following component:Glycerine 3-6 parts by weight, 1,2- hexylene glycol 0.3-0.6 parts by weight, Sensiva SC50 0.05-0.1 parts by weight, butanediol 3-5 parts by weight, xanthans 0.05-0.1 parts by weight, Sodium Hyaluronate 0.005-0.02 parts by weight, glycine betaine 2-3 parts by weight, allantoin 0.05-0.1 parts by weight, dipotassium glycyrrhizinate 0.05-0.1 weight Part, Anjidew NL50 0.4-0.6 parts by weight, sodium acrylate/sodium acryloyldimethyl taurate copolymers 0.75-0.85 parts by weight, different ten Six alkane 0.45-0.55 parts by weight, Polyoxyethylene Sorbitan Monooleate 0.15-0.19 parts by weight, the smooth oleate 0.05-0.06 weight of sorb Part, ring five dimethyl silicone polymer 1.5-3 parts by weight, dimethyl silicone polymer 3.5-5.5 parts by weight, dimethiconol 0.5-0.8 parts by weight, octyl polymethyl siloxane 0.5-0.8 parts by weight, Dimethicone Crosspolymer 0.15-0.3 Parts by weight, caprylic/capric triglyceride 1.5-2.5 parts by weight, carbonic acid dioctyl ester 1.5-2.5 parts by weight, saualane 1-2 weight Part, tridecanol trimellitate 0.5-1.5 parts by weight, phytosterol/docosyl alcohol/octyl decanol lauroyl glutamate ester 0.2- 0.6 parts by weight, tocopherol (vitamin E) 0.05-0.15 parts by weight, PEG-45 stearate 0.5-0.8 parts by weight, butter fruit Set fruit fat 0.5-1.5 parts by weight, budding short stalk enzyme polysaccharide 0.2-0.5 parts by weight, -26 0.05 weight of PPG-26- butylol polyethers Part, 0.04 parts by weight of PEG-40 rilanit specials, silver-colored 0.0006 parts by weight, carbohydrate isomer 0.3-0.6 parts by weight, lemon Lemon acid 0.25-0.55 parts by weight, sodium citrate 0.25-0.55 parts by weight, glycerol caprylate 0.1-0.3 parts by weight, Artemisia capillaris flower Extract 0.005-0.05 parts by weight, cloves flower extract 0.005-0.02 parts by weight, purslane extract 0.01-0.5 weight Part.
In addition, the invention also discloses the preparation method of the above-mentioned re-surface intensive wrinkle correct that compacts, include the following steps:
(1)Prepare essence matrix:Water intaking, glycerine, 1,2- hexylene glycols, Sensiva SC50, butanediol, xanthans, hyaluronic acid Sodium, glycine betaine, allantoin, dipotassium glycyrrhizinate, Anjidew NL50 are added water phase pot, are heated to 70-75 DEG C, stir evenly, and are pumped into vacuum In mulser;Take the smooth oleate of isohexadecane, Polyoxyethylene Sorbitan Monooleate, sorb, ring five dimethyl silicone polymer, poly dimethyl silicon Oxygen alkane, dimethiconol, octyl polymethyl siloxane, Dimethicone Crosspolymer, caprylic/capric glycerine Three esters 1, carbonic acid dioctyl ester, saualane, tridecanol trimellitate, phytosterol/docosyl alcohol/octyl decanol lauroyl paddy ammonia Acid esters, tocopherol (vitamin E), PEG-45 stearates, Butyrospermum parkii fruit fat are added oil phase pot, are heated to 70-75 DEG C, stir It mixes uniformly, is pumped into vacuum emulsifying machine;Booting is stirred homogeneous, and sodium acrylate/acryloyldimethyl is added in homogeneous 3 minutes Taurate Copolymer, continues homogeneous 5 minutes, starts to cool down;40 DEG C are cooled to, budding short stalk enzyme polysaccharide, PPG-26- fourths is added Alcohol polyethers -26, PEG-40 rilanit specials, silver, carbohydrate isomer, citric acid, sodium citrate, glycerol caprylate, oriental wormwood Wormwood artemisia flower extract, cloves flower extract, purslane extract, continue to stir evenly, be cooled to room temperature;It is filling to get essence base Matter;
(2)By myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate, palmityl tripeptides -5, Rhizoma Zingiberis zerumbet extraction Object, rye seed extract are added into above-mentioned essence matrix, stir evenly to get the re-surface intensive wrinkle correct that compacts.
Compared with prior art, the present invention has the advantages that:
The present invention is by containing the myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate of certain content with specific The palmityl tripeptides -5 of amount are compounded, and are aided with the Rhizoma Zingiberis zerumbet extract of certain content and the rye seed extraction of certain content Object is prepared by the coordinated of each component and resists skin ageing, reduces the good essence composition of wrinkle effect, by this Essence composition is added in essence matrix and obtains the re-surface intensive wrinkle correct that compacts, which there is good moisturizing and barrier maintenance to imitate Fruit, while skin elasticity and degree of compacting can be significantly improved, reduce wrinkle.
Specific implementation mode
It is further illustrated the present invention below by specific implementation mode, following embodiment is the preferable embodiment party of the present invention Formula, but embodiments of the present invention are not limited by following embodiments.
Raw material used in embodiment and comparative example of the present invention is as follows, but is not limited only to the following raw material:
Myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate, manufacturer DSM;
Palmityl tripeptides -5, manufacturer DSM;
Rhizoma Zingiberis zerumbet extract, manufacturer are SEDERMA SAS;
Rye seed extract, manufacturer Silab.
The testing standard or test method of each performance indicator:
Essence composition prevents skin aging from testing:
1)Sample preparation:Above-mentioned test group raw material is taken, deionized water is added, is uniformly mixed, it is spare.
2)Test method:Take healthy 1 monthly age male nude mouse, 14 ± 2g of weight random to be grouped:Model group, experiment 1-3 groups;Model group:D- galactolipin 1000mg/kg are subcutaneously injected in daily nape part, and combine long wavelength (365nm) Skin of back is irradiated with short wavelength (254nm) ultraviolet light, long wavelength ultraviolet light cumulative exposure intensity is 260J/cm2, shortwave Long cumulative exposure intensity 6.5J/cm2;Test group:Injection and the same model group of illumination, on the basis of injection and illumination, then to Test specimen is smeared at back, and 2 times a day, each 2mL, continuously injection and illumination 6 weeks, model group is slow in action, and back wrinkle is bright It is aobvious, it is in apparent aging sign, is put to death after drug withdrawal 2d and skin is taken to carry out Biochemical Indexes;
3)Biochemical Indexes method:Every nude mice back skin tissues block about 1g or so is taken according to grouping, is floated through physiological saline It washes, subcutaneous fat and other connective tissues is dispelled with scalpel, filter paper blots, and weighs, and precision weighs the life of 9 times of amounts of skin histology Brine is managed, the physiological saline of 2/3 amount is poured into the mortar equipped with tissue block, grinds, is ground to after being shredded with ophthalmology is small Until can't see massive texture, thick homogenate is poured into small beaker, it, will be small with the net mortar of normal saline flushing of residue 1/3 3min is continuously crushed in beaker Ultrasonic Pulverization instrument ice bath, then multigelation 3 times, make cellular content be free on liquid completely Tissue homogenate is centrifuged 15min in 3500r/min, takes supernatant to be measured, according to SOD, HYP and MDA by Xiang Zhong Kit specification method measures, and test result is as shown in table 2.
Embodiment A1-A5 and comparative example B1-B4:The preparation of essence composition
By the proportioning of table 1 by myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate, palmityl tripeptides -5, red ball Four kinds of ginger extract, rye seed extract components, are added deionized water, and mixing stirs evenly to get essence composition.
The each group distribution ratio of table 1 embodiment A1-A5 and comparative example B1-B4(Parts by weight)
2 nude mice skin tissue Biochemical Indexes measurement result of table
Application Example 1-5 and comparative example 1-4:The re-surface intensive wrinkle correct that compacts containing essence composition
It is formulated by shown in table 3, prepares essence matrix first:Water intaking, glycerine, 1,2- hexylene glycols, Sensiva SC50, butanediol, Xanthans, Sodium Hyaluronate, glycine betaine, allantoin, dipotassium glycyrrhizinate, Anjidew NL50 are added water phase pot, are heated to 70-75 DEG C, stir It mixes uniformly, is pumped into vacuum emulsification agent;Take the smooth oleate of isohexadecane, Polyoxyethylene Sorbitan Monooleate, sorb, five poly dimethyl silicon of ring Oxygen alkane, dimethyl silicone polymer, dimethiconol, octyl polymethyl siloxane, dimethyl silicone polymer cross-linked polymeric Object, caprylic/capric triglyceride 1, carbonic acid dioctyl ester, saualane, tridecanol trimellitate, phytosterol/docosyl alcohol/pungent Oil phase pot is added in base decyl alcohol lauroyl glutamate ester, tocopherol (vitamin E), PEG-45 stearates, Butyrospermum parkii fruit fat, It is heated to 70-75 DEG C, is stirred evenly, is pumped into vacuum emulsification agent;Booting is stirred homogeneous, and acrylic acid is added in homogeneous 3 minutes Sodium/sodium acryloyldimethyl taurate copolymers, continues homogeneous 5 minutes, starts to cool down;40 DEG C are cooled to, the short stalk that sprouts is added Enzyme polysaccharide, PPG-26- butylol polyethers -26, PEG-40 rilanit specials, silver, carbohydrate isomer, citric acid, citric acid Sodium, glycerol caprylate, Artemisia capillaris flower extract, cloves flower extract, purslane extract, continue to stir evenly, are cooled to room Temperature;It is filling to get;Up to essence matrix;
Wherein, 5 parts by weight of glycerine, 1,2- hexylene glycols, 0.5 parts by weight, 0.1 parts by weight of Sensiva SC50,4 parts by weight of butanediol, 0.08 parts by weight of xanthans, 0.005 parts by weight of Sodium Hyaluronate, 3 parts by weight of glycine betaine, 0.1 parts by weight of allantoin, glycyrrhizic acid two 0.05 parts by weight of potassium, 0.5 parts by weight of Anjidew NL50,0.8 parts by weight of sodium acrylate/sodium acryloyldimethyl taurate copolymers, different ten Smooth 0.055 parts by weight of oleate of six alkane, 0.5 parts by weight, 0.17 parts by weight of Polyoxyethylene Sorbitan Monooleate, sorb, five poly dimethyl silicon of ring 2.5 parts by weight of oxygen alkane, 4.5 parts by weight of dimethyl silicone polymer, 0.65 parts by weight of dimethiconol, the poly- methyl silicon of octyl 0.65 parts by weight of oxygen alkane, 0.2 parts by weight of Dimethicone Crosspolymer, 2 parts by weight of caprylic/capric triglyceride, carbon 2 parts by weight of dioctyl phthalate, 1.2 parts by weight of saualane, 1 parts by weight of tridecanol trimellitate, phytosterol/docosyl alcohol/pungent 0.4 parts by weight of base decyl alcohol lauroyl glutamate ester, 0.1 parts by weight of tocopherol, 0.6 parts by weight of PEG-45 stearates, butter fruit Set 1 parts by weight of fruit fat, 0.3 parts by weight of budding short stalk enzyme polysaccharide, -26 0.05 parts by weight of PPG-26- butylol polyethers, PEG-40 hydrogen Change 0.04 parts by weight of castor oil, silver-colored 0.0006 parts by weight, 0.45 parts by weight of carbohydrate isomer, 0.4 parts by weight of citric acid, lemon 0.4 parts by weight of lemon acid sodium, 0.2 parts by weight of glycerol caprylate, 0.025 parts by weight of Artemisia capillaris flower extract, cloves flower extract 0.01 parts by weight, 0.25 parts by weight of purslane extract;
It is formulated by shown in table 3, then prepares the re-surface intensive wrinkle correct that compacts:By the essence group described in embodiment A1-A5 and comparative example B1-B4 It closes object to be added into the above-mentioned essence matrix being prepared, stir evenly to get the re-surface intensive wrinkle correct that compacts.
The each group distribution ratio of table 3 embodiment 1-5 and comparative example 1-4(Parts by weight)And each testing performance index result
Compact re-surface intensive wrinkle correct mildness test:30 people experimenters are selected, do closure patch test, by embodiment 1-5 and right Respectively about 0.03ml is applied in spot examination device for what ratio 1-4 was prepared compact re-surface intensive wrinkle correct, and external application special adhesive tape is pasted on subject Back removes tested material after 24 hours, 0.5 after patch test, observation dermoreaction in 24,48 hours, according to《Cosmetics Technical specification of security》Dermoreaction grade scale records its result in 2015 editions.The results show that in 30 people 0 there is skin not Good reaction.The re-surface intensive wrinkle correct that compacts that embodiment 1-5 and comparative example 1-4 are prepared is subjected to the on probation of 30 people, examination respectively simultaneously With the results show that not occurring allergic phenomena.It is good to be indicated above the product mildness.
Compact re-surface intensive wrinkle correct the effect of test:30 people experimenters are selected, respectively before use, after use 4 weeks to subject Instrument test.Mainly following 5 indexs of test index:
(1)Cuticula moisture:It is tested 3 times and is averaged using Corneometer, test result is as shown in table 3.Such as Fruit result judgement:After product use, test zone cuticula moisture content value increases in conspicuousness, indicates that the given the test agent has Moistening effect.
(2)Transepidermal water is lost in:It is averaged using Tewameter follow-on tests 20s, test result such as 3 institute of table Show.If result judgement:After product use, test zone TEWL values are reduced in conspicuousness, indicate that the given the test agent makes skin Barrier function improves.
(3)Skin elasticity Q1:It is tested 2 times and is averaged using Cutometer, test result is as shown in table 3.Such as Fruit result judgement:After product use, test zone Q1 values increase in conspicuousness, and indicating that the given the test agent has improves skin bullet The effect of property.
(4)Skin-tightening F4:It is tested 2 times and is averaged using Cutometer, test result is as shown in table 3.Such as Fruit result judgement:After product use, test zone F4 values are reduced in conspicuousness, indicate that the given the test agent has improvement skin tight The effect of cause is spent.
(5)Texture:Using VC98 shootings test 2 times, is analyzed with SELS, take 2 average values, test result is such as Shown in table 3.If test zone wrinkle of skin parameter SEw values are reduced in conspicuousness, indicates that the given the test agent has and reduce skin The effect of microgroove.

Claims (7)

1. a kind of essence composition, which is characterized in that by weight, including following component:
(A)0.005-0.015 parts of myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate;
(B)- 5 0.005-0.015 parts of palmityl tripeptides;
(C)0.1-0.3 parts of Rhizoma Zingiberis zerumbet extract;
(D)0.05-0.25 parts of rye seed extract.
2. essence composition according to claim 1, which is characterized in that the component(A)With component(B)Weight ratio be 1:1-2.
3. essence composition according to claim 1, which is characterized in that the Rhizoma Zingiberis zerumbet extract passes through supercritical CO2Skill Art is extracted to obtain, and contains 400-700ppm zerumbones.
The re-surface intensive wrinkle correct 4. one kind is compacted, including claim 1-3 any one of them essence compositions.
5. the re-surface intensive wrinkle correct according to claim 4 that compacts further includes by weight essence matrix and water.
6. the re-surface intensive wrinkle correct according to claim 5 that compacts, which is characterized in that the essence matrix, including following component:It is sweet Oily 3-6 parts by weight, 1,2- hexylene glycol 0.3-0.6 parts by weight, Sensiva SC50 0.05-0.1 parts by weight, butanediol 3-5 weight Part, xanthans 0.05-0.1 parts by weight, Sodium Hyaluronate 0.005-0.02 parts by weight, glycine betaine 2-3 parts by weight, allantoin 0.05-0.1 parts by weight, dipotassium glycyrrhizinate 0.05-0.1 parts by weight, Anjidew NL50 0.4-0.6 parts by weight, sodium acrylate/acryloyl two N-methyltaurine sodium copolymer 0.75-0.85 parts by weight, isohexadecane 0.45-0.55 parts by weight, Polyoxyethylene Sorbitan Monooleate 0.15- The smooth oleate 0.05-0.06 parts by weight of 0.19 parts by weight, sorb, ring five dimethyl silicone polymer 1.5-3 parts by weight, poly dimethyl Siloxanes 3.5-5.5 parts by weight, dimethiconol 0.5-0.8 parts by weight, octyl polymethyl siloxane 0.5-0.8 weight Part, Dimethicone Crosspolymer 0.15-0.3 parts by weight, caprylic/capric triglyceride 1.5-2.5 parts by weight, carbonic acid Dioctyl ester 1.5-2.5 parts by weight, saualane 1-2 parts by weight, tridecanol trimellitate 0.5-1.5 parts by weight, phytosterol/ Docosyl alcohol/octyl decanol lauroyl glutamate ester 0.2-0.6 parts by weight, tocopherol (vitamin E) 0.05-0.15 parts by weight, PEG-45 stearate 0.5-0.8 parts by weight, Butyrospermum parkii fruit fat 0.5-1.5 parts by weight, budding short stalk enzyme polysaccharide 0.2-0.5 Parts by weight, -26 0.05 parts by weight of PPG-26- butylol polyethers, 0.04 parts by weight of PEG-40 rilanit specials, silver-colored 0.0006 weight Part, carbohydrate isomer 0.3-0.6 parts by weight, citric acid 0.25-0.55 parts by weight, sodium citrate 0.25-0.55 parts by weight, Glycerol caprylate 0.1-0.3 parts by weight, Artemisia capillaris flower extract 0.005-0.05 parts by weight, cloves flower extract 0.005-0.02 Parts by weight, purslane extract 0.01-0.5 parts by weight.
The preparation method of re-surface intensive wrinkle correct 7. a kind of such as claim 4-6 any one of them is compacted, includes the following steps:
(1)Prepare essence matrix:Water intaking, glycerine, 1,2- hexylene glycols, Sensiva SC50, butanediol, xanthans, hyaluronic acid Sodium, glycine betaine, allantoin, dipotassium glycyrrhizinate, Anjidew NL50 are added water phase pot, are heated to 70-75 DEG C, stir evenly, and are pumped into vacuum In mulser;Take the smooth oleate of isohexadecane, Polyoxyethylene Sorbitan Monooleate, sorb, ring five dimethyl silicone polymer, poly dimethyl silicon Oxygen alkane, dimethiconol, octyl polymethyl siloxane, Dimethicone Crosspolymer, caprylic/capric glycerine Three esters 1, carbonic acid dioctyl ester, saualane, tridecanol trimellitate, phytosterol/docosyl alcohol/octyl decanol lauroyl paddy ammonia Acid esters, tocopherol (vitamin E), PEG-45 stearates, Butyrospermum parkii fruit fat are added oil phase pot, are heated to 70-75 DEG C, stir It mixes uniformly, is pumped into vacuum emulsifying machine;Booting is stirred homogeneous, and sodium acrylate/acryloyldimethyl is added in homogeneous 3 minutes Taurate Copolymer, continues homogeneous 5 minutes, starts to cool down;40 DEG C are cooled to, budding short stalk enzyme polysaccharide, PPG-26- fourths is added Alcohol polyethers -26, PEG-40 rilanit specials, silver, carbohydrate isomer, citric acid, sodium citrate, glycerol caprylate, oriental wormwood Wormwood artemisia flower extract, cloves flower extract, purslane extract, continue to stir evenly, be cooled to room temperature;It is filling to get essence base Matter;
(2)By myristyl aminobutyryl valyl amido butyric acid urea trifluoroacetate, palmityl tripeptides -5, Rhizoma Zingiberis zerumbet extraction Object, rye seed extract are added into above-mentioned essence matrix, stir evenly to get the re-surface intensive wrinkle correct that compacts.
CN201810577781.9A 2018-06-07 2018-06-07 A kind of essence composition and the re-surface intensive wrinkle correct and preparation method thereof that compacts being made from it Pending CN108420776A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288781A (en) * 2018-09-03 2019-02-01 芜湖凌梦电子商务有限公司 Whitening and softening skin essence cream and preparation method thereof
CN109303734A (en) * 2018-12-13 2019-02-05 北京天奇益人健康科技有限公司 A kind of perfume Flos Nelumbinis extract and its preparing the application in cosmetics
CN109431872A (en) * 2018-12-25 2019-03-08 樊利平 A kind of body lotion and preparation method thereof for orange peel line of dispelling
CN109730949A (en) * 2019-03-04 2019-05-10 广州市华晟健康产业有限公司 It is a kind of with crease-resistant compact effect Medical-use cold compress pad pasting
CN112022751A (en) * 2020-10-12 2020-12-04 惠州市好好爱日化用品有限公司 Tightening lifting mask
CN114099379A (en) * 2021-10-27 2022-03-01 广东润和生物科技有限公司 Coenzyme Q10 high-efficiency moisturizing and wrinkle-soothing essence lotion and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104622779A (en) * 2015-01-08 2015-05-20 上海圣婕化妆品有限公司 Antiageing and repairing polypeptide facial mask essence and preparation method thereof
CN105287320A (en) * 2015-12-08 2016-02-03 广州市花安堂生物科技有限公司 Mild lifting and repairing eye cream and preparation method thereof
CN106580826A (en) * 2016-12-21 2017-04-26 宁波君瑞生物科技有限公司 Cream with effects of increasing skin moisture and reducing wrinkles
CN107411997A (en) * 2017-06-26 2017-12-01 上海新高姿化妆品有限公司 A kind of anti-aging face cream composition
CN107961208A (en) * 2017-12-06 2018-04-27 广州蜜妆生物科技有限公司 A kind of small molecule modeling face is compacted spraying and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104622779A (en) * 2015-01-08 2015-05-20 上海圣婕化妆品有限公司 Antiageing and repairing polypeptide facial mask essence and preparation method thereof
CN105287320A (en) * 2015-12-08 2016-02-03 广州市花安堂生物科技有限公司 Mild lifting and repairing eye cream and preparation method thereof
CN106580826A (en) * 2016-12-21 2017-04-26 宁波君瑞生物科技有限公司 Cream with effects of increasing skin moisture and reducing wrinkles
CN107411997A (en) * 2017-06-26 2017-12-01 上海新高姿化妆品有限公司 A kind of anti-aging face cream composition
CN107961208A (en) * 2017-12-06 2018-04-27 广州蜜妆生物科技有限公司 A kind of small molecule modeling face is compacted spraying and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288781A (en) * 2018-09-03 2019-02-01 芜湖凌梦电子商务有限公司 Whitening and softening skin essence cream and preparation method thereof
CN109303734A (en) * 2018-12-13 2019-02-05 北京天奇益人健康科技有限公司 A kind of perfume Flos Nelumbinis extract and its preparing the application in cosmetics
CN109431872A (en) * 2018-12-25 2019-03-08 樊利平 A kind of body lotion and preparation method thereof for orange peel line of dispelling
CN109730949A (en) * 2019-03-04 2019-05-10 广州市华晟健康产业有限公司 It is a kind of with crease-resistant compact effect Medical-use cold compress pad pasting
CN112022751A (en) * 2020-10-12 2020-12-04 惠州市好好爱日化用品有限公司 Tightening lifting mask
CN114099379A (en) * 2021-10-27 2022-03-01 广东润和生物科技有限公司 Coenzyme Q10 high-efficiency moisturizing and wrinkle-soothing essence lotion and preparation method thereof

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