CN113018230A

CN113018230A - Composition and preparation method and application thereof

Info

Publication number: CN113018230A
Application number: CN202110173580.4A
Authority: CN
Inventors: 滕春雨; 吴忠健; 陈光文; 邓伟健
Original assignee: Guangzhou Meijing Biotechnology Co ltd
Current assignee: Guangzhou Meijing Biotechnology Co ltd
Priority date: 2021-02-07
Filing date: 2021-02-07
Publication date: 2021-06-25

Abstract

The invention discloses a composition, a preparation method and application thereof, and relates to the technical field of cosmetics. The composition comprises the following components in parts by weight: 0.01-0.18 part of hydrolyzed sclerotium rolfsii gum, 0.1-1.5 parts of hydroxyethyl piperazine ethane sulfonic acid, 0.15-1.5 parts of acetyl chitosamine, 0.3-2 parts of nicotinamide, 0.3-3 parts of rose water, 0.001-0.009 part of dimethyl silanol hyaluronate, 0.001-0.009 part of phenoxyethanol, 0.0005-0.0045 part of ethylhexyl glycerol, 0.13-0.675 part of glycerol, 0.02-0.075 part of diglucosylgallic acid and 0.5-5.0 parts of saccharomycete polypeptide. The composition provided by the application has multiple effects of moisturizing, resisting wrinkles, whitening, relieving, repairing and the like.

Description

Composition and preparation method and application thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to a composition and a preparation method and application thereof.

Background

The skin is the largest organ of the human body and has important protection effect on the human body. Moreover, the skin also highlights the appearance of the individual, and healthy, bright white, elastic skin may make people look younger and more vibrant, especially female siblings.

However, since the skin of a human body is directly in contact with the external environment, various stimuli from the external environment may be applied to the skin at any time, especially the skin of the face, and the skin may cause various skin problems such as inflammation, aging, allergy, dryness, etc. due to the external stimuli. Meanwhile, skin aging is an inevitable proposition, and generally, after the age of 25, the skin condition of a female slips down and gradually ages, and the problems of wrinkles, color spots, dryness and the like are also accompanied. Therefore, care of the skin, particularly the facial skin, in daily life becomes extremely important, and therefore a skin care product full of precious enamel grows.

The essence is used as a high-priced skin care product, has the effects of rapidly supplementing skin moisture and quickly repairing skin, and plays an important role in daily skin care of people. However, many of the currently marketed essences are still single in efficacy, mainly have moisturizing efficacy, and are mostly high in efficiency for moisturizing and moisturizing or for moisturizing and wrinkle removal. Moreover, some essence in the market contains hormone, so that the dependence of human skin can be caused; or, the skin containing irritant substances is easy to cause skin allergy, so that allergic symptoms such as pruritus and red swelling are caused, and the skin is not protected from health.

Disclosure of Invention

Based on the above, the invention aims to overcome the defects of the prior art and provide the composition with multiple effects of moisturizing, resisting wrinkles, whitening, relieving, repairing and the like.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows: the composition comprises the following components in parts by weight: 0.01-0.18 part of hydrolyzed sclerotium rolfsii gum, 0.1-1.5 parts of hydroxyethyl piperazine ethane sulfonic acid, 0.15-1.5 parts of acetyl chitosamine, 0.3-2 parts of nicotinamide, 0.3-3 parts of rose water, 0.001-0.009 part of dimethyl silanol hyaluronate, 0.001-0.009 part of phenoxyethanol, 0.0005-0.0045 part of ethylhexyl glycerol, 0.13-0.675 part of glycerol, 0.02-0.075 part of diglucosylgallic acid and 0.5-5.0 parts of saccharomycete polypeptide.

TIA yeast peptide contains abundant B vitamins, glutathione, etc., effectively reduces melanin deposition on skin, and makes skin maintain fair. TIA yeast peptide activates skin cell renewal, removes old skin epidermis through self cell replacement, and makes skin brand new. The TIA yeast peptide has good water solubility and fat-soluble structure, and can penetrate into each part in cells to play a good antioxidation function; effectively remove the toxic effect of free radicals on cells, thereby playing the role of protecting cells and skin. TIA yeast peptide has strong inhibition ability to tyrosinase activity. Further studies have shown that it can bind to the double copper ion active center of tyrosinase, and is a competitive inhibitor of tyrosinase. On the other hand, TIA yeast peptide has good antioxidant properties, while the first two stages of melanin formation are an oxidation process. Among the mechanisms of whitening and removing freckles, antioxidation and competitive inhibition are the two most common and important mechanisms of action, and TIA yeast peptide has the two functions at the same time. The core active peptide in the TIA yeast peptide is a special component, wherein 2-OH and 4-OH on a B ring are very close to the structures of-OH on aromatic rings of L-dopa and L-tyrosine, so that the core active peptide is easy to combine with an enzyme active center to generate extremely strong inhibition on enzyme, a peptide bond structure in a C region is introduced to play a good role in protecting and stabilizing the structures of 2-OH and 4-OH, the water solubility of the core active peptide is greatly enhanced, and the C structure has extremely strong oxidation resistance.

According to the application, three components of dimethiconol hyaluronic acid ester, phenoxyethanol and ethylhexylglycerin are selected to be matched for use, the action mechanism of Si in the skin is utilized, and a silane group with a silicon element is connected on the basis of hyaluronic acid, so that the effects of moisturizing and locking water of hyaluronic acid are achieved, meanwhile, the silicon element in skin connective tissue is supplemented, the normal form of fibroblast is maintained, and the regular connective tissue structure is maintained; can promote fibroblast proliferation, promote collagen production, enhance skin elasticity, maintain skin youth state, and resist aging. Can promote keratinocyte proliferation and renew keratinocyte. Can promote the renewal of hyaluronic acid on epidermis and cells, repair epidermis injury, and promote epidermis renewal. The skin moisturizing cream has rich hydroxyl groups, is intelligently combined with water on the surface of the skin, forms dynamic balance of the water on the surface of the skin, and simultaneously fixes the water in skin tissues from the bottom of skin muscles to the surface to form real three-dimensional intelligent moisturizing; the human body external skin experiment proves that the hyaluronic acid composition can promote the synthesis of hyaluronic acid in the skin and supplement endogenous hyaluronic acid. The 3 components provided by the application are used in a combined manner, and the silane groups are combined, so that the extracellular matrix of the skin dermis can be reconstructed, the metabolic balance of cells can be maintained, the skin barrier can be enhanced, and the sensitive skin can be repaired.

The glycerol and the diglucosylgallic acid are matched for use, the whole formula is very stable, and the color is not easy to change; and can be used for resisting free radicals, inhibiting the generation path of Nf-kB, inhibiting PGE2, preventing DHA injury, inhibiting the activity of tyrosinase, preventing melanin transfer, inhibiting the activity of MTF, whitening skin and brightening skin from 7 aspects.

The hydroxyethyl piperazine ethane sulfonic acid has the following advantages: the water solubility is strong; the permeability of cell membranes is weak; the acid and alkali continuity is strong; almost no metal chelation; the chemical stability is strong; has no toxic effect on cells.

The composition with multiple effects of moisturizing, resisting wrinkles, whitening, soothing, repairing and the like is obtained by matching and using the hydrolyzed sclerotium rolfsii gum, the hydroxyethyl piperazine ethane sulfonic acid, the acetyl chitosamine, the nicotinamide, the rose water, the dimethyl silanol hyaluronic acid ester, the phenoxyethanol, the ethylhexyl glycerin, the diglucoside gallic acid and the yeast polypeptide and combining the advantages of each component to realize mutual synergistic interaction.

Preferably, the composition comprises the following components in parts by weight: 0.1 part of hydrolyzed sclerotium rolfsii gum, 0.5 part of hydroxyethyl piperazine ethane sulfonic acid, 0.5 part of acetyl chitosamine, 1 part of nicotinamide, 2 parts of rose water, 0.005 part of dimethyl silanol hyaluronic acid ester, 0.005 part of phenoxyethanol, 0.001 part of ethylhexyl glycerol, 0.425 part of glycerol, 0.075 part of diglucosylgallic acid and 2 parts of saccharomycete polypeptide. Through a great deal of experimental research of the inventor, the effect of the obtained composition is optimal when the composition is prepared according to the proportion.

Furthermore, the invention provides the use of said composition in cosmetics.

Further, the present invention provides a multipurpose essence comprising the composition.

Preferably, the multi-effect essence further comprises the following components in parts by weight: 0.01-0.1 part of EDTA disodium, 0.1-0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.35 part of sodium hyaluronate, 0.02-0.18 part of allantoin, 0.15-0.6 part of p-hydroxyacetophenone, 0.1-0.5 part of triethanolamine, 0.2-1.5 parts of PEG/PPG/polybutylene glycol-8/5/3 glycerol, 1.0-5.0 parts of butanediol, 0.1-0.4 part of propylene glycol, 0.05-0.2 part of glyceryl caprylate and 0.05-0.2 part of caprylyl hydroximic acid.

Further preferably, the multi-effect essence also comprises the following components in parts by weight: 0.02 part of EDTA disodium, 0.3 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.2 part of sodium hyaluronate, 0.1 part of allantoin, 0.3 part of p-hydroxyacetophenone, 0.3 part of triethanolamine, 1 part of PEG/PPG/polytetramethylene glycol-8/5/3 glycerol, 2 parts of butanediol, 0.1 part of propylene glycol, 0.05 part of glyceryl caprylate and 0.08 part of caprylyl hydroximic acid.

The invention also provides a preparation method of the multi-effect essence, which comprises the following steps:

(1) sequentially adding EDTA disodium, acrylic acid (acrylate)/C10-30 alkanol acrylate cross-linked polymer, hydrolyzed sclerotium rolfsii gum, sodium hyaluronate, allantoin and p-hydroxyacetophenone into water, continuously stirring and heating, and uniformly dissolving to obtain transparent liquid;

(2) uniformly stirring triethanolamine and water, adding the triethanolamine and the water into the transparent liquid obtained in the step (1), and preserving heat to obtain a mixed liquid A;

(3) uniformly stirring dimethiconol hyaluronic acid ester, phenoxyethanol, ethylhexyl glycerol and water to obtain a mixed solution B; uniformly stirring glycerol, diglucosylgallic acid and water to obtain a mixed solution C;

(4) cooling the mixed solution A obtained in the step (2), sequentially adding hydroxyethyl piperazine ethanesulfonic acid, acetyl chitosamine, nicotinamide, PEG/PPG/polytetramethylene glycol-8/5/3 glycerin, rose water, the mixed solution B obtained in the step (3), the mixed solution C obtained in the step (3) and the yeast polypeptide after cooling, and uniformly stirring to obtain a mixed solution D;

(5) cooling the mixed solution D obtained in the step (4), adding a mixed solution of butanediol, propylene glycol, glyceryl caprylate and caprylyl hydroximic acid after cooling, and uniformly stirring to obtain a mixed solution E;

(6) and (5) cooling the mixed liquor E obtained in the step (5), filtering and discharging to obtain the multi-effect essence.

Preferably, in the step (1), the heating temperature is 80-82 ℃; in the step (2), the weight ratio of triethanolamine to water is as follows: triethanolamine: 1:3-5 of water, and keeping the temperature for 10-15 min; in the step (3), the weight ratio of the mixed solution of the dimethiconol hyaluronic acid ester, the phenoxyethanol and the ethylhexyl glycerin to the water is as follows: mixing liquid: water 1: 35-45; the weight ratio of the mixed liquid of the glycerol and the diglucosylgallic acid to the water is as follows: mixing liquid: 4-6: 2-4.

Preferably, in the step (4), the temperature is reduced to below 48 ℃; in the step (5), the temperature is reduced to be below 40 ℃; premixing butanediol, propylene glycol, glyceryl caprylate and caprylyl hydroximic acid, and adding; in the step (6), the temperature is reduced to below 38 ℃.

Compared with the prior art, the invention has the beneficial effects that:

the multi-effect essence disclosed by the invention has multiple effects of moisturizing, resisting wrinkles, whitening, relieving, repairing and the like, can be used for effectively nursing skin, effectively relieving multiple skin problems including aging, dryness, wrinkles, color spots, allergy, inflammation and the like, enables the skin to be tender and moist, improves the skin elasticity, reduces skin wrinkles, improves the skin glossiness, is moist, beautiful and active, and effectively protects the skin health. Moreover, the multi-effect essence has soft and comfortable skin feel, is not sticky and greasy, is fast to absorb, and has good use experience.

According to the preparation method, the multi-effect essence with good stability and uniform dispersed texture can be prepared by strictly controlling the adding steps and the compatibility mixing conditions of the components according to the characteristics of the raw material components in the multi-effect essence.

Detailed Description

To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.

In the present application, examples 1 to 6 were set up, and the raw material selection of specific examples 1 to 6 is shown in table 1:

table 1 raw material composition (mass percentage, total 100%)

The preparation method of the multi-effect essence disclosed in the embodiments 1-6 comprises the following steps:

(1) sequentially adding EDTA disodium, acrylic acid (acrylate)/C10-30 alkanol acrylate cross-linked polymer, hydrolyzed sclerotium rolfsii gum, sodium hyaluronate, allantoin and p-hydroxyacetophenone into water, continuously stirring and heating at 80-82 ℃, and uniformly dissolving to obtain transparent liquid;

(2) uniformly stirring triethanolamine and water, wherein the weight ratio of the triethanolamine to the water is as follows: triethanolamine: water ═ 1:3-5 is possible within this range, and the specific case is specifically added depending on the preparation process. Within this range, the addition is possible, depending on the preparation process. Adding the transparent liquid obtained in the step (1), and preserving heat for 10-15min to obtain a mixed liquid A;

(3) uniformly stirring dimethyl silanol hyaluronic acid ester, phenoxyethanol, ethylhexyl glycerol and water to obtain a mixed solution B, wherein the weight ratio of the mixed solution of the dimethyl silanol hyaluronic acid ester, the phenoxyethanol and the ethylhexyl glycerol to the water is as follows: mixing liquid: water 1:35-45 is possible within this range, with specific additions depending on the manufacturing process. (ii) a Uniformly stirring glycerol, diglucosylgallic acid and water, wherein the weight ratio of the mixed solution of the glycerol and the diglucosylgallic acid to the water is as follows: mixing liquid: obtaining mixed liquor C by taking water as 4-6: 2-4;

(4) cooling the mixed solution A obtained in the step (2) to below 48 ℃, sequentially adding hydroxyethyl piperazine ethanesulfonic acid, acetyl chitosamine, nicotinamide, PEG/PPG/polytetramethylene glycol-8/5/3 glycerin, rose water, the mixed solution B obtained in the step (3), the mixed solution C obtained in the step (3) and yeast polypeptide after cooling, and uniformly stirring to obtain a mixed solution D;

(5) cooling the mixed solution D obtained in the step (4) to below 40 ℃, adding the mixed solution of butanediol, propylene glycol, glyceryl caprylate and caprylyl hydroxamic acid after cooling, and uniformly stirring to obtain a mixed solution E;

(6) and (5) cooling the mixed liquor E obtained in the step (5) to below 38 ℃, filtering and discharging to obtain the multi-effect essence.

Meanwhile, the application is provided with comparative examples, and the specific comparative examples are set as shown in the following tables 2 and 3:

table 2 raw material composition (mass percentage, total 100%) of the multi-effect essence of comparative examples 1 to 3

Table 3 raw material composition (mass percentage, total 100%) of the multi-effect essence of comparative examples 4 to 7

Effect verification

Test example 1 stability test

The multi-effect essence liquids of examples 1 to 6 and comparative examples 1 to 7 are transparent fluid liquids, and pH values measured by pH measurement (1:10 water diluted solution) are 5.2, 5.8, 5.3, 6.0, 5.6, 5.9, 4.7, 6.4, 5.8, 5.9, 4.8, 6.0, and 6.1, respectively.

The multi-effect essence liquids of the examples 1 to 6 and the comparative examples 1 to 7 are subjected to physicochemical property tests of heat resistance (48 +/-2 ℃, 3 months, and room temperature recovery), cold resistance (-15 +/-2 ℃, 3 months, and room temperature recovery) and cold-heat circulation (24 hours and 3 cycles at the normal temperature and the normal temperature of-15 ℃), and the results show that no abnormalities such as layering and air bubbles occur, and the multi-effect essence liquids of the examples 1 to 6 and the comparative examples 1 to 7 have good physicochemical stability and good weather-proof quality guarantee effect.

Test example 2 test for efficacy in use

The multi-effect essence of example 2 and comparative example 1 was subjected to a patch test to verify whether it was irritating to the human body, so as to perform an efficacy test for safe direct use.

(1) Patch test

Test samples: the multi-effect essence of example 2 and the multi-effect essence of comparative example 1.

The test population: 60 people, 20-35 years old, 30 women and 30 men, and has healthy skin and no allergic history of skin diseases. Randomly divided into 2 groups, each group was 30 people, and the proportion of male and female in each group was 1:1, the multi-effect essence of the test example 2 and the comparative example 1 were respectively corresponding in units of groups.

The test method comprises the following steps: the multi-effect essence of example 2 and comparative example 1 was subjected to spot test according to the human skin spot test method of technical safety standards for cosmetics (2015 edition), and the results were recorded according to the skin reaction grading standard. Wherein, the skin reaction grading standard is as follows: negative reaction, grade 0. +/-., suspicious reaction, only weak erythema, grade 1. Positive reaction (erythema reaction), erythema, infiltration, edema, and pimple, grade 2. + + strong positive reaction (herpetic response), erythema, infiltration, edema, papules, herpes, response beyond the test area, grade 3. + + + +, very strong positive reaction (confluent herpes reaction), obvious erythema, severe infiltration, edema, confluent herpes, reaction beyond the test area, grade 4.

And (3) testing results: all the reactions are negative, and no adverse reaction cases occur. The multi-effect essence of example 2 and the multi-effect essence of comparative example 1 both showed no irritation to the human body and could be safely and directly used. Based on the results, the multi-effect essences of examples 1 to 6 and comparative examples 1 to 7 were subjected to direct use tests.

(2) Improvement of skin conditions

According to the patch test results, the multi-effect essence of the embodiments 1 to 6 and the comparative examples 1 to 7 is subjected to an efficacy test for direct use.

Test samples: the multiple-effect essence of examples 1-6 and the multiple-effect essence of comparative examples 1-7.

The test population: 39 people, female staff aged 25-35 years old, healthy skin and no allergic history of skin diseases. The multiple-effect essence of examples 1 to 6 and the multiple-effect essence of comparative examples 1 to 7 were used in groups of 3 persons each at random.

The test method comprises the following steps: after the face of the subject is washed by clean water, the corresponding test sample is smeared on the face for skin care and maintenance, and the skin care and maintenance are respectively carried out 1 time in the morning and at the evening every day and are continuously used for 1 month. In order to verify the efficacy of the multi-effect essence, the subject does not use other skin care products after using the multi-effect essence in the test period.

The facial skin condition of the subject before and after use was measured, including the measurement of skin moisture content, skin elasticity, skin wrinkles and skin glossiness, and the measurement results are shown in tables 4 to 8.

(2-1) improvement of moisture content of facial skin

The facial skin Moisture was measured with a skin Moisture meter, and the Measurement results are represented by set Moisture Measurement values (MMV/%), and are shown in table 4.

Table 4 improvement of moisture content of facial skin by the multi-effect essence of examples 1 to 6 and comparative examples 1 to 7

(2-2) improvement of facial skin elasticity

The skin elasticity was measured using a skin elasticity tester (current meter dual MPA580), and the ratio Uv/Ue of the plastic part to the elastic part of the skin was taken as a value, and the smaller the ratio, the better the skin elasticity was, and the measurement results are shown in table 5.

Table 5 improvement of facial skin elasticity by the multi-effect essences of examples 1 to 6 and comparative examples 1 to 7

(2-3) improvement of wrinkles on facial skin

Skin wrinkle was measured using a Skin image analysis system (Skin visualizer SV600), and the measurement results are shown in Table 6.

Table 6 the multi-effect essences of examples 1 to 6 and comparative examples 1 to 7 improve skin wrinkles

(2-4) improvement of facial skin gloss

The skin glossiness was measured using a skin glossiness measuring instrument, and the lifting rate was calculated, and the results are shown in table 7.

Table 7 improvement of facial skin gloss by the multi-effect essence of examples 1 to 6 and comparative examples 1 to 7

From the results, the multi-effect essence liquids of the embodiments 1 to 6 have various effects of moisturizing, anti-wrinkle, whitening, soothing, repairing and the like, so that the skin is moisturized, the elasticity of the skin is improved, the wrinkles of the skin are reduced, the glossiness of the skin is improved, the skin is moist, beautiful and active, and the health of the skin is effectively protected.

(3) Evaluation of Using results

For the skin improvement use test described above, the evaluation of the use experience of each subject was counted, and the use experience was scored by each subject (full score of 10, average within group), and the evaluation results are shown in table 8.

Table 8 evaluation results of use tests of the multi-effect essences of examples 1 to 6 and comparative examples 1 to 7

The statistical results in table 6 show that the multi-effect essence of examples 1 to 6 has good use experience.

3. Anti-allergy relief effect test

The test substance: the multi-effect essence of examples 1 to 6 and comparative examples 1 to 7.

Subject: 65 volunteers participating in the experiment are female employees of 25-35 years old. 65 volunteers were randomly divided into 13 groups of 5 persons each, and the multiple-effect essence of examples 1 to 6 and comparative examples 1 to 7 was tried on each group of volunteers.

The test method comprises the following steps: each subject stimulates the skin on the inner side of the left arm with 6 wt% of capsaicin, so that the skin is allergic and produces burning sensation, 1ml of corresponding test object is smeared on the part stimulated by the capsaicin according to grouping conditions, the feedback conditions of the subjects are respectively recorded at 10min, 30min and 60min after the test object is smeared, the recovery degree of the skin in different periods is judged according to the burning sensation fed back by the subjects on the tested part, and the test results are shown in table 9.

Table 9 anti-allergy relief test results of the multi-effect essences of examples 1 to 6 and comparative examples 1 to 7

Note: the degree of recovery was divided into 4 grades, "I" indicating complete disappearance of the burning sensation, "II" indicating mild burning sensation, "III" indicating moderate burning sensation, and "IV" indicating severe burning sensation.

The table shows that the multi-effect essence liquids of examples 1 to 6 have a faster and more efficient soothing effect and can quickly eliminate the stimulation compared with the multi-effect essence liquids of comparative examples 1 to 7.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims

1. The composition is characterized by comprising the following components in parts by weight: 0.01-0.18 part of hydrolyzed sclerotium rolfsii gum, 0.1-1.5 parts of hydroxyethyl piperazine ethane sulfonic acid, 0.15-1.5 parts of acetyl chitosamine, 0.3-2 parts of nicotinamide, 0.3-3 parts of rose water, 0.001-0.009 part of dimethyl silanol hyaluronate, 0.001-0.009 part of phenoxyethanol, 0.0005-0.0045 part of ethylhexyl glycerol, 0.13-0.675 part of glycerol, 0.02-0.075 part of diglucosylgallic acid and 0.5-5.0 parts of saccharomycete polypeptide.

2. The composition of claim 1, comprising the following components in parts by weight: 0.1 part of hydrolyzed sclerotium rolfsii gum, 0.5 part of hydroxyethyl piperazine ethane sulfonic acid, 0.5 part of acetyl chitosamine, 1 part of nicotinamide, 2 parts of rose water, 0.005 part of dimethyl silanol hyaluronic acid ester, 0.005 part of phenoxyethanol, 0.001 part of ethylhexyl glycerol, 0.425 part of glycerol, 0.075 part of diglucosylgallic acid and 2 parts of saccharomycete polypeptide.

3. Use of a composition according to claim 1 or 2 in cosmetics.

4. A multipurpose essence comprising the composition of claim 1 or 2.

5. The multi-effect essence of claim 4, further comprising the following components in parts by weight: 0.01-0.1 part of EDTA disodium, 0.1-0.5 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.1-0.35 part of sodium hyaluronate, 0.02-0.18 part of allantoin, 0.15-0.6 part of p-hydroxyacetophenone, 0.1-0.5 part of triethanolamine, 0.2-1.5 parts of PEG/PPG/polybutylene glycol-8/5/3 glycerol, 1.0-5.0 parts of butanediol, 0.1-0.4 part of propylene glycol, 0.05-0.2 part of glyceryl caprylate and 0.05-0.2 part of caprylyl hydroximic acid.

6. The multi-effect essence of claim 5, further comprising the following components in parts by weight: 0.02 part of EDTA disodium, 0.3 part of acrylic acid (ester)/C10-30 alkanol acrylate cross-linked polymer, 0.2 part of sodium hyaluronate, 0.1 part of allantoin, 0.3 part of p-hydroxyacetophenone, 0.3 part of triethanolamine, 1 part of PEG/PPG/polytetramethylene glycol-8/5/3 glycerol, 2 parts of butanediol, 0.1 part of propylene glycol, 0.05 part of glyceryl caprylate and 0.08 part of caprylyl hydroximic acid.

7. The method for preparing the multi-effect essence of claim 5 or 6, comprising the steps of:

8. The method for preparing multi-effect essence according to claim 7, wherein in the step (1), the heating temperature is 80-82 ℃; in the step (2), the weight ratio of triethanolamine to water is as follows: triethanolamine: 1:3-5 of water, and keeping the temperature for 10-15 min; in the step (3), the weight ratio of the mixed solution of the dimethiconol hyaluronic acid ester, the phenoxyethanol and the ethylhexyl glycerin to the water is as follows: mixing liquid: water 1: 35-45; the weight ratio of the mixed solution of the glycerol and the diglucosylgallic acid to the water is as follows: mixing liquid: 4-6: 2-4.

9. The method for preparing multi-effect essence according to claim 7, wherein in the step (4), the temperature is reduced to below 48 ℃; in the step (5), the temperature is reduced to be below 40 ℃; premixing butanediol, propylene glycol, glyceryl caprylate and caprylyl hydroximic acid, and adding; in the step (6), the temperature is reduced to below 38 ℃.