CN110664685A

CN110664685A - Essence emulsion for improving anti-glycation effect of skin and preparation method thereof

Info

Publication number: CN110664685A
Application number: CN201911040527.6A
Authority: CN
Inventors: 何梦蝶; 张文泽
Original assignee: Zhejiang British Tree Biotechnology Co Ltd
Current assignee: Zhejiang Yingshu Cosmetics Technology Co ltd
Priority date: 2019-10-29
Filing date: 2019-10-29
Publication date: 2020-01-10
Anticipated expiration: 2039-10-29
Also published as: CN110664685B

Abstract

The invention discloses essence milk for improving skin anti-saccharification effect and a preparation method thereof, wherein the essence milk comprises the following components: deionized water, glycerin, butylene glycol, hydrolyzed sodium hyaluronate, carnosine liquid, tranexamic acid, carbomer, sclerotium rolfsii, hydroxyethyl piperazine ethane sulfonic acid, nicotinamide, squalane, cetyl ethylhexanoate, cetearyl olivate, sorbitan olivate, isononyl isononanoate, cetearyl alcohol, jojoba seed oil, a monkey bread pulp extract, a complex fruit acid extract, a caffeine-cyclodextrin composition, a chlorella extract, a yeast lysate extract, palmitoyl hexapeptide-12 liquid, a ginseng root extract, a grape seed extract, a yerba mate tea extract, a portulaca oleracea extract, olive oil, and palmitoyl tetrapeptide-7 liquid. The essence emulsion for improving the anti-glycation effect of the skin has the advantages of promoting cell regeneration, increasing collagen, relieving the glycation degree of the skin and improving dark and yellow skin color.

Description

Essence emulsion for improving anti-glycation effect of skin and preparation method thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to essence milk for improving anti-glycation efficacy of skin and a preparation method thereof.

Background

Because social competition is increasingly fierce and the rhythm of life and work is accelerated, people in many workplaces have daily meals and overtime work all night, and the normal work and rest habits are disturbed by the life style of reversing day and night.

The metabolism of a human body is slowed down after the human body is usually decocted, after excessive sugar is taken in the human body, the excessive sugar cannot be absorbed and converted into power consumption, the excessive sugar can be dissociated in the human body, when the sugar is combined with protein and attached to collagen, an irreversible glycosylation product AGE is generated, the AGE can enable the collagen to be broken or disordered and generate a brown substance, the skin color of the face is dark, the cells can reduce the contractility along with the accumulation of the AGE, the activity of the cells is reduced, the skin of the face shows aging phenomena of pores, large and large fine lines, loose skin and the like, and the skin loses the sense of smoothness and elasticity because the collagen is damaged by the AGE, and wrinkles are not easy to smooth and continuously deepen.

The anti-glycation needs to reduce the intake of sugar and also needs to make skin care work, so the invention provides the essence milk which can improve the anti-glycation effect of the skin and inhibit the dark yellow skin color and is particularly suitable for people staying up at night.

Disclosure of Invention

Aiming at the defects in the prior art, the first purpose of the invention is to provide the essence emulsion for improving the anti-glycation efficacy of the skin, which has the advantages of being suitable for people staying up night, promoting cell regeneration, effectively increasing collagen of the skin, relieving the glycation degree of the skin and improving dark and yellow skin color.

The second purpose of the invention is to provide a preparation method of the essence milk for improving the anti-glycation efficacy of the skin, which has the advantages of simple process and operation.

In order to achieve the first object, the invention provides the following technical scheme: the essence milk for improving the anti-saccharification effect of the skin consists of a phase A, a phase B and a phase C, wherein the phase A consists of the following components in parts by weight: 50.21-55.21 parts of deionized water, 3-10 parts of glycerol, 2-8 parts of butanediol, 0.02-0.25 part of hydrolyzed sodium hyaluronate, 0.3-3 parts of carnosine liquid, 0.05-2 parts of 1, 2-pentanediol, 0.01-2 parts of tranexamic acid, 0.01-1 part of carbomer, 0.01-0.5 part of sclerotium rolfsii, 0.001-0.3 part of disodium EDTA, 0.2-2 parts of hydroxyethyl piperazine ethane sulfonic acid and 0.2-2 parts of nicotinamide;

the phase B comprises the following components in parts by weight: 2-8 parts of squalane, 0.5-6 parts of cetyl ethylhexanoate, 0.1-5 parts of cetearyl olive oleate, 1-6 parts of sorbitan olive oleate, 0.3-3 parts of isononyl isononanoate, 0.1-1.2 parts of cetearyl alcohol and 0.1-5 parts of jojoba seed oil;

the phase C comprises the following components in parts by weight: 0.1-3 parts of Paeonia suffruticosa pulp extracting solution, 0.1-3 parts of compound fruit acid extracting solution, 0.3-5 parts of caffeine-cyclodextrin composition, 0.1-10 parts of chlorella extracting solution, 0.1-2 parts of yeast lysate extracting solution, 0.1-3 parts of palmitoyl hexapeptide-12 solution, 0.01-3 parts of ginseng root extracting solution, 0.1-2 parts of grape seed extracting solution, 0.1-10 parts of yerba mate tea extracting solution, 0.05-3 parts of purslane extracting solution, 0.01-1 part of olive oil, 0.05-2 parts of palmitoyl tetrapeptide-7 solution, 0.4-1.5 parts of moisturizing antibacterial solution, 0.02-0.5 part of triethanolamine and 0.001-0.8 part of essence.

By adopting the technical scheme, as the phase A uses butanediol as a solvent, the antibacterial skin care cream has the advantage of smaller irritation than propylene glycol, the sclerotium rolfsii gum has a high-efficiency skin repair function, can effectively prevent cytoplasm peroxidation caused by ultraviolet rays, has good anti-inflammatory activity and light aging resistance, promotes the recovery of damaged skin, improves the water retention of skin, moisturizes, lubricates and elastics the skin, forms a transparent air-permeable film, has good permeability, can permeate into the horny layer of the skin, improves the skin quality, increases the skin brightness, prevents skin aging by using carnosine liquid, improves the skin whiteness, can quickly wrap redundant sugar in the skin by using carnosine, protects collagen from being saccharified, keeps the skin compact and transparent, accelerates the metabolism by using oleamide, accelerates the shedding of horny containing melanocytes, and the hydroxyethyl piperazine ethanesulfonic acid is used as a biological buffering agent, the product has the advantages of protecting the pH value balance of the product, being capable of mildly removing cutin and increasing the absorption rate of effective components under the combined action of nicotinamide, being capable of exciting the activity of attenuated cells after being absorbed by epidermal cells, promoting the synthesis of collagen, lightening the yellow color of protein saccharified, and having obvious improvement effect on dark yellow skin, color spots, wrinkles and the like.

The squalane in the phase B has better affinity to the skin, can inhibit peroxidation of skin lipid, effectively permeates into the skin, promotes proliferation of skin basal cells, relieves skin aging, improves and eliminates chloasma, can promote pore opening, promotes blood circulation, promotes metabolism of cells, helps repair broken cells, can promote penetration of jojoba seed oil with better permeability, and isononyl isononanoate enables the essential milk to have better spreadability and dispersivity, reduces viscosity and greasy feeling of the essential milk, and enables the skin to feel fresh.

In the phase C, the macaque fruit pulp extract, the chlorella extract, the compound fruit acid extract and the like are used, so that the cleaning and anti-oxidation effects are achieved, the regeneration of skin cells can be promoted, the complexion and smooth fine lines are improved, the yerba mate tea extract and the grape seed extract can remove free radicals, inflammation is eliminated, aging is delayed, the immunity is enhanced, damaged cells are repaired and maintained, the division and proliferation of new cells are promoted, the regeneration of collagen and elastin is accelerated, the elasticity and tightness of the skin are enabled, the generation of collagen can be promoted by the palmitoyl tetrapeptide-7 solution and the palmitoyl hexapeptide-12 solution, the activity of elastin is increased, the facial lines are relaxed, the fine lines and wrinkles of the ginseng root extract are relieved, the antibacterial and anti-inflammatory effects are achieved, acne can be prevented, the cell regeneration can be promoted, the collagen of the skin is effectively increased, the effect of moistening and smoothing the skin is achieved, and the damage of the skin collagen to the AGEs can be resisted to, slowing down the saccharification effect of the skin, the extract of the saccharomycete lysate can effectively eliminate free radicals in the body, promote metabolism, protect cells, prolong the service life of the cells, delay senility, has high absorption rate, high efficiency and saccharification resistance, improves the dark and yellow state of the skin, ensures that the facial skin is more uniform and bright, has good ductility and high fineness of the ginseng root extract, can improve the permeability of the components of the extract of the saccharomycete lysate, the extract of the monkey tree extract and the like, and accelerates the extract of the saccharomycete lysate. Absorbing the extract of Paeonia Macaca.

Further, the phase A consists of the following components in parts by weight: 51.21-53.21 parts of deionized water, 5-7 parts of glycerol, 4-7 parts of butanediol, 0.08-0.15 part of hydrolyzed sodium hyaluronate, 0.5-1.5 parts of carnosine liquid, 0.2-1.5 parts of 1, 2-pentanediol, 0.15-1 part of tranexamic acid, 0.05-0.1 part of carbomer, 0.1-0.3 part of sclerotium rolfsii, 0.01-0.1 part of EDTA disodium, 0.5-1.5 parts of hydroxyethyl piperazine ethane sulfonic acid and 0.5-1.5 parts of nicotinamide;

the phase B comprises the following components in parts by weight: 3-6 parts of squalane, 1-4 parts of cetyl ethyl hexanoate, 1.5-4 parts of cetearyl olive oleate, 2.5-3.5 parts of sorbitan olive oleate, 1-2 parts of isononyl isononanoate, 0.3-1 part of cetearyl alcohol and 1-3 parts of jojoba seed oil;

the phase C comprises the following components in parts by weight: 1-2.5 parts of Paeonia suffruticosa pulp extracting solution, 1-2.5 parts of composite fruit acid extracting solution, 1.5-3 parts of caffeine-cyclodextrin composition, 1-5 parts of chlorella extracting solution, 0.8-1.5 parts of yeast lysate extracting solution, 0.8-1.5 parts of palmitoyl hexapeptide-12 solution, 1-2.5 parts of ginseng root extracting solution, 0.5-1.3 parts of grape seed extracting solution, 0.5-5 parts of yerba mate extracting solution, 1-2.5 parts of portulaca oleracea extracting solution, 0.08-0.5 part of olive oil, 0.15-1.5 parts of palmitoyl tetrapeptide-7 solution, 0.7-1.3 parts of moisturizing antibacterial solution, 0.1-0.35 part of triethanolamine and 0.03-0.1 part of essence.

By adopting the technical scheme, the dosage of the raw materials of the phase A, the phase B and the phase C is more accurate, so that the prepared essence milk can promote cell regeneration, relieve the skin saccharification degree and improve the dark skin color effect more obviously.

Further, the compound fruit acid extracting solution is prepared by mixing the following components in parts by weight: 74-76 parts of water, 4-5 parts of sugarcane extract, 5-6 parts of vaccinium myrtillus extract, 4-5 parts of sweet orange fruit extract, 5-6 parts of maple extract and 4-5 parts of citron fruit extract.

By adopting the technical scheme, the vaccinium myrtillus extract can improve microcirculation, regulate blood flow, resist oxidation strongly, eliminate free radicals and effectively block melanin formation, the citron fruit extract contains various components such as malic acid, pectin, vitamins and the like, can effectively inhibit the damage of free radicals in vivo to skin and delay skin aging, has stronger antioxidation, the sugarcane extract can promote skin blood circulation and keep moisture for a long time, the acer comosum extract and the sweet orange fruit extract can resist aging, increase skin smoothness and luster, and improve the antibacterial, anti-inflammatory, moisturizing, soothing and anti-allergy effects of the essence milk.

Further, the carnosine liquid is prepared by mixing the following components in parts by weight: 4.5-5.5 parts of carnosine, 4.5-5.5 parts of pentanediol and 89-91 parts of glycerol.

By adopting the technical scheme, the pentanediol has broad-spectrum antibacterial activity, can effectively inhibit gram-negative bacteria, positive bacteria, saccharomycetes and mould fungi, can improve the antibacterial property of the essence milk, has good skin moisture retention property, can reduce the loss of water in the skin, enables the skin to be soft and smooth, can improve the skin moistening function of the essence milk, can be dissolved in water, can be uniformly mixed with the carnosine in the water, and can synergistically increase the collagen regeneration capacity of the skin, improve the skin quality, brighten the skin color and remove wrinkles.

Further, the macaque fruit pulp extracting solution is prepared by mixing the following components in parts by weight: 97.9-98 parts of water, 0.8-1 part of Adansonia dubia pulp extract, 0.4-0.5 part of sodium benzoate, 0.3-0.35 part of xanthan gum and 0.4-0.5 part of potassium sorbate.

By adopting the technical scheme, the macaque nut pulp extracting solution prepared by mixing xanthan gum serving as an emulsifier, potassium sorbate and sodium benzoate serving as preservatives has better spreadability and long-acting storage property.

Further, the chlorella extracting solution is prepared by mixing the following components in parts by weight: 5.5-7.5 parts of chlorella extract, 1.5-2.5 parts of pentanediol, 1.8-2.2 parts of 1, 2-hexanediol, 5.5-6.5 parts of butanediol and 82-84 parts of water.

By adopting the technical scheme, the pentanediol has excellent moisture retention and corrosion resistance, the butanediol has good moisture retention, no greasy feeling and is relatively fresh, and the fine greasy feeling and the penetrability of the essence milk can be enhanced.

Further, the yeast lysate extracting solution is prepared by mixing water and yeast lysate extract in a mass ratio of 7-7.5: 2.5-3;

the mass ratio of caffeine to cyclodextrin in the caffeine-cyclodextrin composition is 1: 1;

the moisturizing antibacterial liquid is prepared by mixing the following components in parts by weight: 15-20 parts of glyceryl caprylate, 74-81.5 parts of 1, 2-pentanediol and 3.5-6 parts of caprylyl hydroximic acid.

By adopting the technical scheme, the caffeine can reduce fat, increase blood circulation of hair line blood vessels and nourish skin, but the permeability of the caffeine is poor, and the cyclodextrin can replace a penetration enhancer to change the arrangement sequence of lipid in the stratum corneum and increase the permeability of cells so as to promote the rate of the caffeine penetrating through the stratum corneum;

the glyceryl caprylate can permeate and be adsorbed on lipid part of skin, has good moisturizing effect, and can be used in combination with caprylyl hydroximic acid with antiseptic effect to improve moisturizing, antibacterial and antiseptic effects of essence milk.

Further, the palmitoyl hexapeptide-12 liquid is prepared by mixing the following components in parts by weight: 20-25 parts of glycerol polymethacrylate, 74.5-79.9 parts of polyethylene glycol-8 and 0.1-0.5 part of palmitoyl hexapeptide-12;

the palmitoyl tetrapeptide-7 solution is prepared by mixing the following components in parts by weight: 76.9-77 parts of water, 0.8-1.2 parts of palmitoyl tetrapeptide-7, 1.5-2 parts of 1, 2-hexanediol, 18-22 parts of glycerol and 0.1-0.15 part of ethylhexyl glycerol.

Further, the ginseng root extract is prepared by mixing the ginseng root extract, water and butanediol in a mass ratio of 0.1:14.9-15: 5; the grape seed extract is prepared by mixing grape seed extract, water and butanediol with the mass ratio of 0.1:14.9-15: 5; the yerba mate tea extract is prepared by mixing yerba mate tea extract, water and butanediol in a mass ratio of 0.1:14.9-15: 5; the purslane extracting solution is prepared by mixing the following components in parts by weight: 74.5-74.9 parts of water, 25 parts of butanediol and 0.1-0.5 part of purslane extract.

By adopting the technical scheme, the purslane extract can prevent dryness and aging, increase the comfort level of skin, remove free radicals, improve the comfort level of skin, enable the skin to absorb a certain amount of polysaccharide and vitamin, moisten the skin and prevent the phenomenon of saccharification caused by the reaction of redundant sugar and collagen.

In order to achieve the second object, the invention provides the following technical scheme: a preparation method of essence milk for improving skin anti-saccharification effect comprises the following steps:

(1) adding the phase A raw material into a homogenizer, homogenizing at high speed for 3-5min, heating to 85-90 deg.C, stirring, dispersing, and keeping the temperature for 30-35 min;

(2) adding the phase B raw material into a reactor, heating to 85-90 ℃, stirring and dispersing uniformly, and keeping the temperature for later use;

(3) pumping the raw materials of phase B into a homogenizer containing phase A, homogenizing at high speed for 10-15min, stirring and cooling, cooling to 45 deg.C, sequentially adding the raw materials of phase C, stirring, and cooling to room temperature to obtain the final product.

By adopting the technical scheme, the phase A raw material is homogenized and dispersed, the phase B is dispersed uniformly, the phase A raw material and the phase B raw material are mixed and homogenized, and the phase C materials are added in sequence.

In conclusion, the invention has the following beneficial effects:

firstly, as the hydroxyethyl piperazine ethane sulfonic acid can mildly remove the skin cuticle, squalane can promote pores to open, promote blood circulation and increase the absorption rate of effective components, so that the effective components such as carnosine, nicotinamide and jojoba seed oil can conveniently permeate into the skin cuticle and be absorbed by epidermal cells, the skin aging can be prevented, the yellow color of protein after saccharification is lightened, and the skin problems such as dark yellow color, color spots and the like are improved and eliminated, thereby improving the anti-saccharification effect of the skin.

Secondly, in the invention, the ginseng root extract and the yeast lysate extract are used in the phase C, and the ginseng root extract has the effects of resisting bacteria, diminishing inflammation, preventing acnes, promoting cell regeneration and increasing skin collagen, the yeast lysate extract has the effects of eliminating in-vivo free radicals, promoting metabolism and delaying senescence, and the ginseng root extract and the yeast lysate extract are cooperatively used, so that the ginseng root extract can enhance the permeability of the yeast lysate extract, accelerate the absorption of essence milk, resist the damage of AGEs to collagen, slow down the saccharification of skin, eliminate fine wrinkles and improve the phenomenon of dark and yellow skin.

Thirdly, the yerba mate tea extract, the grape seed extract, the palmitoyl tetrapeptide-7 liquid and the palmitoyl hexapeptide-12 liquid are used in the invention, which can repair and maintain damaged cells, promote division and proliferation of new cells, accelerate regeneration of collagen, increase activity of elastin, promote consciousness restoration, promote metabolism, prevent reduction of elastin content, maintain skin elasticity, and are used in cooperation with the palmitoyl tetrapeptide-7 liquid and the palmitoyl hexapeptide-12 liquid, so that the essence milk has strong capacity of removing free radicals, can relax facial lines, and relieve fine lines and wrinkles,

fourth, the caffeine-cyclodextrin composition is used in the present invention because caffeine can reduce fat, increase blood circulation of capillary vessels, and nourish the skin, but because caffeine has poor permeability, cyclodextrin can replace a permeation enhancer, change the arrangement order of lipids in the stratum corneum, and increase intercellular permeability to enhance the rate at which caffeine permeates the stratum corneum.

Detailed Description

The present invention will be described in further detail with reference to examples.

Examples

Examples 1-7 where the hydrolyzed sodium hyaluronate was selected from Shandong Furrida, type HA, Sclerotinia sclerotiorum was selected from Spiborum USA, carbomer was selected from Luoborun USA, Hojojoba seed oil was selected from Guangzhou Mingde Fine chemical technology Co., Ltd, and niacinamide was selected from HFP niacinamide sold by Imperial group of Netherlands.

Example 1: an essence milk for improving skin anti-glycation efficacy, which consists of a phase A, a phase B and a phase C, and the preparation method of the essence milk for improving skin anti-glycation efficacy comprises the following steps:

adding the phase A raw material into a homogenizer, homogenizing at high speed for 3min, heating to 85 deg.C, stirring for dispersing, and keeping the temperature for 30 min; wherein the phase A raw materials are shown in Table 1, and comprise 50kg of deionized water, 3kg of glycerol, 2kg of butanediol, 0.02kg of hydrolyzed sodium hyaluronate, 0.3kg of carnosine liquid, 0.05kg of 1, 2-pentanediol, 0.01kg of tranexamic acid, 0.01kg of carbomer, 0.01kg of sclerotium rolfsii, 0.001kg of disodium EDTA, 0.2kg of hydroxyethyl piperazine ethane sulfonic acid and 0.1kg of oleamide, wherein the carnosine liquid is prepared by mixing 4.5kg of carnosine, 4.5kg of pentanediol and 89kg of glycerol;

(2) adding the phase B raw material into a reactor, heating to 85 ℃, stirring and dispersing uniformly, and keeping the temperature for later use;

wherein the raw materials of phase B are shown in Table 1, and comprise 2kg of squalane, 0.5kg of cetyl ethylhexanoate, 0.1kg of cetearyl olivate, 1kg of sorbitan olivate, 0.3kg of isononyl isononanoate, 0.1kg of cetearyl alcohol and 0.1kg of jojoba oil;

(3) pumping the raw material of phase B into a homogenizer containing phase A, homogenizing at high speed for 10min, stirring and cooling, adding the raw materials of phase C when the temperature is reduced to 45 deg.C, stirring, and cooling to room temperature to obtain product;

wherein the C phase raw materials are shown in Table 1, and comprise 0.1kg Paeonia suffruticosa pulp extract, 0.1kg compound fruit acid extract, 0.3kg caffeine-cyclodextrin composition, 0.1kg Chlorella extract, 0.1kg yeast cell lysis extract, 0.1kg palmitoyl hexapeptide-12 solution, 0.01kg ginseng root extract, 0.1kg grape seed extract, 0.1kg yerba mate extract, 0.05kg Portulaca oleracea extract, 0.01kg olive oil, 0.05kg palmitoyl tetrapeptide-7 solution, 0.4kg moisturizing antibacterial solution, 0.02kg triethanolamine, 0.001kg essence;

wherein the extract solution of Adansonia simplicifolia pulp is prepared by mixing 97.9kg of water, 0.8kg of Adansonia simplicifolia pulp extract, 0.4kg of sodium benzoate, 0.3kg of xanthan gum and 0.4kg of potassium sorbate, the composite fruit acid extract is prepared by mixing 74kg of water, 4kg of sugarcane extract, 5kg of Vaccinium myrtillus extract, 4kg of Citrus sinensis fruit extract, 5kg of Acer saccharum extract and 4kg of Citrus medica fruit extract, the caffeine-cyclodextrin composition is prepared by mixing caffeine and cyclodextrin in a mass ratio of 1:1, the Chlorella vulgaris extract is prepared by mixing 5.5kg of Chlorella vulgaris extract, 1.5kg of pentanediol, 1.8kg of 1, 2-hexanediol, 5.5kg of butanediol and 82kg of water, the yeast cell lysis extract is prepared by mixing water and yeast cell lysis extract in a mass ratio of 7:3, the palmitoyl hexapeptide-12 solution is prepared by mixing 20kg of glyceryl polymethacrylate, 74.5kg of polyethylene glycol-8 and 0.5kg palmitoyl hexapeptide-12, the ginseng root extract is prepared by mixing a ginseng root extract, water and butanediol in a mass ratio of 0.1:14.9:5, the grape seed extract is prepared by mixing a grape seed extract, water and butanediol in a mass ratio of 0.1:14.9:5, the yerba mate tea extract is prepared by mixing a yerba mate tea extract, water and butanediol in a mass ratio of 0.1:14.9:5, the portulaca oleracea extract is prepared by mixing 74.5kg of water, 25kg of butanediol and 0.5kg of portulaca oleracea extract, and the palmitoyl tetrapeptide-7 liquid is prepared by mixing the following components in parts by weight: 76.9kg of water, 0.8kg of palmitoyl tetrapeptide-7, 1.5kg of 1, 2-hexanediol, 18kg of glycerol and 0.1kg of ethylhexyl glycerol, wherein the moisturizing and bacteriostasis liquid is prepared by mixing 20kg of glyceryl caprylate, 74kg of 1, 2-pentanediol and 6kg of caprylyl hydroximic acid.

Table 1 essential milk raw material ratios for enhancing skin anti-glycation efficacy in examples 1-7

Example 2: an essence milk for improving skin anti-glycation efficacy, which consists of a phase A, a phase B and a phase C, and the preparation method of the essence milk for improving skin anti-glycation efficacy comprises the following steps:

adding the phase A raw material into a homogenizer, homogenizing at high speed for 4min, heating to 88 deg.C, stirring, dispersing, and keeping the temperature for 33 min; wherein the phase A raw materials are shown in Table 1, and comprise 50.21kg of deionized water, 4kg of glycerol, 3kg of butanediol, 0.05kg of hydrolyzed sodium hyaluronate, 1kg of carnosine liquid, 0.5kg of 1, 2-pentanediol, 0.2kg of tranexamic acid, 0.02kg of carbomer, 0.03kg of sclerotium rolfsii, 0.003kg of disodium EDTA, 0.4kg of hydroxyethylpiperazine ethanesulfonic acid and 0.4kg of oleamide, wherein the carnosine liquid is prepared by mixing 5kg of carnosine, 5kg of pentanediol and 90kg of glycerol;

(2) adding the phase B raw material into a reactor, heating to 88 ℃, stirring and dispersing uniformly, and keeping the temperature for later use;

wherein the raw materials of phase B are shown in Table 1, and comprise 3kg of squalane, 1kg of cetyl ethyl hexanoate, 1.5kg of cetearyl olive oleate, 2kg of sorbitan olive oleate, 0.5kg of isononyl isononanoate, 0.5kg of cetearyl alcohol and 1.5kg of jojoba seed oil;

(3) pumping the raw material of phase B into a homogenizer containing phase A, homogenizing at high speed for 13min, stirring and cooling, adding the raw materials of phase C when the temperature is reduced to 45 deg.C, stirring, and cooling to room temperature to obtain product;

wherein the C phase raw materials are shown in Table 1, and comprise 1kg Paeonia suffruticosa pulp extract, 1kg compound fruit acid extract, 1.5kg caffeine-cyclodextrin composition, 2kg Chlorella extract, 0.5kg yeast cell lysis extract, 0.5kg palmitoyl hexapeptide-12 solution, 1kg ginseng root extract, 0.3kg grape seed extract, 1kg yerba mate tea extract, 0.08kg Portulaca oleracea extract, 0.05kg olive oil, 0.1kg palmitoyl tetrapeptide-7 solution, 0.5kg moisturizing antibacterial solution, 0.05kg triethanolamine, and 0.05kg essence;

wherein the extract solution of Adansonia simplicifolia pulp is prepared by mixing 98kg of water, 0.9kg of Adansonia simplicifolia pulp extract, 0.45kg of sodium benzoate, 0.33kg of xanthan gum and 0.45kg of potassium sorbate, the composite fruit acid extract solution is prepared by mixing 75kg of water, 4.5kg of sugarcane extract, 5.5kg of Vaccinium myrtillus extract, 4.5kg of Citrus sinensis fruit extract, 5.5kg of Acer saccharina extract and 4.5kg of Citrus medica fruit extract, the caffeine-cyclodextrin composition is prepared by mixing caffeine and cyclodextrin at a mass ratio of 1:1, the extract solution of Chlorella vulgaris is prepared by mixing 6.5kg of Chlorella vulgaris extract, 2kg of pentanediol, 2kg 1, 2-hexanediol, 6kg of butanediol and 83kg of water, the yeast extract solution is prepared by mixing water at a mass ratio of 7.3:2.7 and yeast lysate extract, the palmitoyl hexapeptide-12 solution is prepared by mixing 23kg of polymethacrylate, 76.7kg of polyethylene glycol-8 and 0.3kg of palmitoyl hexapeptide-12, the ginseng root extracting solution is prepared by mixing a ginseng root extract, water and butanediol in a mass ratio of 0.1:15:5, the grape seed extracting solution is prepared by mixing a grape seed extract, water and butanediol in a mass ratio of 0.1:15:5, the yerba mate extracting solution is prepared by mixing a yerba mate extract, water and butanediol in a mass ratio of 0.1:15:5, the portulaca oleracea extracting solution is prepared by mixing 74.7kg of water, 25kg of butanediol and 0.3kg of portulaca oleracea extract, and the palmitoyl tetrapeptide-7 liquid is prepared by mixing the following components in parts by weight: 77kg of water, 1kg of palmitoyl tetrapeptide-7, 1.8kg of 1, 2-hexanediol, 20kg of glycerol and 0.13kg of ethylhexyl glycerol, and the moisturizing antibacterial liquid is prepared by mixing 18kg of glyceryl caprylate, 77kg of 1, 2-pentanediol and 5kg of caprylyl hydroximic acid.

Example 3: an essence milk for improving skin anti-glycation efficacy, which consists of a phase A, a phase B and a phase C, and the preparation method of the essence milk for improving skin anti-glycation efficacy comprises the following steps:

adding the phase A raw material into a homogenizer, homogenizing at high speed for 5min, heating to 90 deg.C, stirring, dispersing, and keeping the temperature for 35 min; wherein the phase A raw materials are shown in Table 1 and comprise 51.21kg of deionized water, 5kg of glycerol, 4kg of butanediol, 0.08kg of hydrolyzed sodium hyaluronate, 1.5kg of carnosine liquid, 0.25kg of 1, 2-pentanediol, 0.5kg of tranexamic acid, 0.03kg of carbomer, 0.05kg of sclerotium rolfsii, 0.005kg of disodium EDTA, 0.8kg of hydroxyethylpiperazine ethanesulfonic acid and 0.8kg of oleamide, wherein the carnosine liquid is prepared by mixing 5.5kg of carnosine, 5.5kg of pentanediol and 89kg of glycerol;

(2) adding the phase B raw material into a reactor, heating to 90 ℃, stirring and dispersing uniformly, and keeping the temperature for later use;

wherein the raw materials of phase B are shown in Table 1, and comprise 5kg of squalane, 2kg of cetyl ethylhexanoate, 2kg of cetearyl olivate, 2.5kg of sorbitan olivate, 1kg of isononyl isononanoate, 0.8kg of cetearyl alcohol and 2kg of jojoba oil;

(3) pumping the raw material of phase B into a homogenizer containing phase A, homogenizing at high speed for 15min, stirring and cooling, adding the raw materials of phase C when the temperature is reduced to 45 deg.C, stirring, and cooling to room temperature to obtain product;

wherein the C phase raw materials are shown in Table 1, and comprise 1.5kg Palmaria Adinandra berry pulp extract, 1.5kg composite fruit acid extract, 2kg caffeine-cyclodextrin composition, 4kg Chlorella extract, 0.8kg yeast cell lysis extract, 0.8kg palmitoyl hexapeptide-12 solution, 1.5kg ginseng root extract, 0.5kg grape seed extract, 3kg yerba mate tea extract, 1kg Portulaca oleracea extract, 0.08kg olive oil, 0.15kg palmitoyl tetrapeptide-7 solution, 0.7kg moisturizing antibacterial solution, 0.1kg triethanolamine and 0.08kg essence;

wherein the extract of the fruit pulp of the Papaveris is prepared by mixing 98kg of water, 1kg of the extract of the fruit pulp of the Papaveris, 0.5kg of sodium benzoate, 0.35kg of xanthan gum and 0.5kg of potassium sorbate, the composite fruit acid extract is prepared by mixing 76kg of water, 5kg of sugarcane extract, 6kg of Vaccinium myrtillus extract, 5kg of sweet orange fruit extract, 6kg of Acer saccharinum extract and 5kg of citron fruit extract, the caffeine-cyclodextrin composition is prepared by mixing caffeine and cyclodextrin in a mass ratio of 1:1, the chlorella extract is prepared by mixing 7.5kg of chlorella extract, 2.5kg of pentanediol, 2.2kg of 1, 2-hexanediol, 6.5kg of butanediol and 84kg of lysis water, the yeast extract is prepared by mixing water in a mass ratio of 7.5:2.5 and the yeast lysis extract, the palmitoyl hexapeptide-12 solution is prepared by mixing 25kg of glyceryl methacrylate, 79.9kg of polyethylene glycol-8 and 0.5kg of palmitoyl hexapeptide-12, the ginseng root extracting solution is prepared by mixing a ginseng root extract, water and butanediol in a mass ratio of 0.1:15:5, the grape seed extracting solution is prepared by mixing a grape seed extract, water and butanediol in a mass ratio of 0.1:15:5, the yerba mate extracting solution is prepared by mixing a yerba mate extract, water and butanediol in a mass ratio of 0.1:15:5, the portulaca oleracea extracting solution is prepared by mixing 74.9kg of water, 25kg of butanediol and 0.1kg of portulaca oleracea extract, and the palmitoyl tetrapeptide-7 liquid is prepared by mixing the following components in parts by weight: 77kg of water, 1.2kg of palmitoyl tetrapeptide-7, 2kg of 1, 2-hexanediol, 22kg of glycerol and 0.15kg of ethylhexyl glycerol, wherein the moisturizing antibacterial liquid is prepared by mixing 15kg of glyceryl caprylate, 81.5kg of 1, 2-pentanediol and 3.5kg of caprylhydroxamic acid.

Example 4: an essence milk for improving skin anti-glycation efficacy, which consists of a phase A, a phase B and a phase C, and the preparation method of the essence milk for improving skin anti-glycation efficacy comprises the following steps:

adding the phase A raw material into a homogenizer, homogenizing at high speed for 5min, heating to 90 deg.C, stirring, dispersing, and keeping the temperature for 35 min; wherein the phase A raw materials are shown in Table 1 and comprise 52.21kg of deionized water, 6kg of glycerol, 6kg of butanediol, 0.1kg of hydrolyzed sodium hyaluronate, 0.5kg of carnosine liquid, 0.2kg of 1, 2-pentanediol, 0.15kg of tranexamic acid, 0.05kg of carbomer, 0.1kg of sclerotium rolfsii, 0.01kg of disodium EDTA, 0.5kg of hydroxyethylpiperazine ethanesulfonic acid and 0.5kg of oleamide, wherein the carnosine liquid is prepared by mixing 5kg of carnosine, 5kg of pentanediol and 90kg of glycerol;

wherein the raw materials of phase B are shown in Table 1, and comprise 4kg of squalane, 3kg of cetyl ethylhexanoate, 3kg of cetearyl olivate, 3.5kg of sorbitan olivate, 2kg of isononyl isononanoate, 0.3kg of cetearyl alcohol and 1kg of jojoba oil;

wherein the C phase raw materials are shown in Table 1, and comprise 2kg Paeonia suffruticosa pulp extract, 2kg composite fruit acid extract, 1kg caffeine-cyclodextrin composition, 1kg Chlorella extract, 1kg yeast cell lysis extract, 1kg palmitoyl hexapeptide-12 solution, 2kg ginseng root extract, 1kg grape seed extract, 0.5kg yerba mate tea extract, 1.5kg herba Portulacae extract, 0.1kg olive oil, 0.2kg palmitoyl tetrapeptide-7 solution, 0.9kg moisturizing antibacterial solution, 0.15kg triethanolamine, and 0.03kg essence;

wherein the extract solution of Adansonia simplicifolia pulp is prepared by mixing 98kg of water, 0.9kg of Adansonia simplicifolia pulp extract, 0.45kg of sodium benzoate, 0.32kg of xanthan gum and 0.48kg of potassium sorbate, the composite fruit acid extract solution is prepared by mixing 76kg of water, 4.8kg of sugarcane extract, 5.8kg of Vaccinium myrtillus extract, 4.8kg of Citrus sinensis fruit extract, 5.3kg of Acer saccharinum extract and 4.3kg of Citrus medica fruit extract, the caffeine-cyclodextrin composition is prepared by mixing caffeine and cyclodextrin at a mass ratio of 1:1, the chlorella extract solution is prepared by mixing 7kg of Chlorella vulgaris extract, 2.2kg of pentanediol, 2.1kg of 1, 2-hexanediol, 6.3kg of butanediol and 82kg of water, the yeast extract solution is prepared by mixing water and yeast extract at a mass ratio of 7.5:2.5, the palmitoyl hexapeptide-12 solution is prepared by mixing 23kg of glyceryl polymethacrylate, 76.6kg of polyethylene glycol-8 and 0.4kg of palmitoyl hexapeptide-12, the ginseng root extracting solution is prepared by mixing a ginseng root extract, water and butanediol in a mass ratio of 0.1:15:5, the grape seed extracting solution is prepared by mixing a grape seed extract, water and butanediol in a mass ratio of 0.1:15:5, the yerba mate extracting solution is prepared by mixing a yerba mate extract, water and butanediol in a mass ratio of 0.1:15:5, the portulaca oleracea extracting solution is prepared by mixing 76.6kg of water, 23kg of butanediol and 0.4kg of portulaca oleracea extract, and the palmitoyl tetrapeptide-7 liquid is prepared by mixing the following components in parts by weight: 77kg of water, 1.1kg of palmitoyl tetrapeptide-7, 1.8kg of 1, 2-hexanediol, 19kg of glycerol and 0.14kg of ethylhexyl glycerol, and the moisturizing antibacterial liquid is prepared by mixing 16kg of glyceryl caprylate, 79.5kg of 1, 2-pentanediol and 4.5kg of caprylyl hydroximic acid.

Examples 6 to 7: an essence emulsion for improving skin anti-glycation efficacy is different from that of example 1 in that the raw material formula of phase A, phase B and phase C is shown in Table 1, and the carnosine liquid in phase A is prepared by mixing 5.5kg of carnosine, 5.5kg of pentanediol and 89kg of glycerin; the C phase is prepared by mixing together 97.9kg of water, 0.8kg of Adansonia simplicifolia pulp extract, 0.4kg of sodium benzoate, 0.3kg of xanthan gum and 0.4kg of potassium sorbate, the complex fruit acid extract is prepared by mixing 74kg of water, 4kg of sugarcane extract, 5kg of Vaccinium myrtillus extract, 4kg of Citrus aurantium fruit extract, 5kg of Acer saccharina extract and 4kg of Citrus medica fruit extract, the caffeine-cyclodextrin composition is prepared by mixing caffeine and cyclodextrin at a mass ratio of 1:1, the Chlorella vulgaris extract is prepared by mixing 5.5kg of Chlorella vulgaris extract, 1.5kg of pentanediol, 1.8kg of 1, 2-hexanediol, 5.5kg of lysed butanediol and 82kg of water, the yeast extract is prepared by mixing water at a mass ratio of 7:3 with the yeast lysed extract, the palmitoyl hexapeptide-12 solution is prepared by mixing 20kg of glyceryl polymethacrylate, 74.5kg of polyethylene glycol-8 and 0.5kg palmitoyl hexapeptide-12, the ginseng root extract is prepared by mixing a ginseng root extract, water and butanediol in a mass ratio of 0.1:14.9:5, the grape seed extract is prepared by mixing a grape seed extract, water and butanediol in a mass ratio of 0.1:14.9:5, the yerba mate tea extract is prepared by mixing a yerba mate tea extract, water and butanediol in a mass ratio of 0.1:14.9:5, the portulaca oleracea extract is prepared by mixing 74.5kg of water, 25kg of butanediol and 0.5kg of portulaca oleracea extract, and the palmitoyl tetrapeptide-7 liquid is prepared by mixing the following components in parts by weight: 76.9kg water, 0.8kg palmitoyl tetrapeptide-7, 1.5kg 1, 2-hexanediol, 18kg glycerol and 0.1kg ethylhexyl glycerol, and the moisture-keeping antibacterial liquid is prepared by mixing 20kg glyceryl caprylate, 74kg1, 2-pentanediol, and 6kg caprylyl hydroximic acid

Comparative example

Comparative example 1: an essence emulsion for improving the anti-glycation efficacy of skin is different from the essence emulsion in the embodiment 1 in that the carnosine liquid is not added in the phase A.

Comparative example 2: the essence milk for improving the anti-glycation efficacy of the skin is different from the essence milk in example 1 in that the hydroxyethyl piperazine ethane sulfonic acid is not added in the phase A.

Comparative example 3: an essence emulsion for improving the anti-glycation efficacy of skin is different from the essence emulsion in example 1 in that no squalane is added in phase B.

Comparative example 4: an essence emulsion for improving the anti-glycation efficacy of skin is different from the essence emulsion in the embodiment 1 in that the C phase is not added with the compound fruit acid extracting solution.

Comparative example 5: an essence emulsion for improving the anti-glycation efficacy of skin is different from the essence emulsion in example 1 in that the yerba mate leaf extract is not added in the phase C.

Comparative example 6: an essence emulsion for improving anti-glycation efficacy of skin is different from that of example 1 in that a ginseng root extract and a yeast lysate extract are not added to a C phase.

Comparative example 7: the skin-lightening night-out essence prepared in example 1 of the chinese invention patent application with the application number CN201910186176.3 is used as a control, and consists of phases a, B, C, D, E, F, G and H, wherein: the phase A is prepared from the following components in percentage by mass: 5% of diglycerol, 0.3% of carbomer, 3% of glycerol, 0.06% of polyacrylic acid, 2% of betaine and 0.1% of disodium ethylene diamine tetraacetate; the phase B is prepared from the following components in percentage by mass: 5% of butanediol and 0.3% of sodium hyaluronate; the phase C is prepared from the following components in percentage by mass: nicotinamide 1%, diethoxyethyl succinate 2%, p-hydroxyacetophenone 0.5%, hexylene glycol 0.5%, arbutin 0.05%, dipotassium glycyrrhizinate 0.1%, centella asiatica extract 0.01%; the phase D is prepared from the following components in percentage by mass: 1% of a prickly pear stem extract, 1% of a reed extract, 1% of a licorice root extract, 1% of a angelica root extract, 1% of a salvia miltiorrhiza root extract, 1% of a dogwood fruit extract and 1% of a wolfberry root extract; the phase E is prepared from the following components in percentage by mass: rose oil 0.05%, polyethylene glycol-40 hydrogenated castor oil 0.2%; the phase F is prepared from the following components in percentage by mass: 0.2% of sodium hydroxide and 2% of rose water; the G phase is prepared from the following components in percentage by mass: 0.1% of colorant and 1% of rose water; the colorant is sunset yellow; the H phase is prepared from the following components in percentage by mass: 69.53 percent of rose water.

Performance test

Firstly, product safety assessment (human skin patch test):

1. the test substance: examples 1 to 7 and comparative examples 1 to 7 essence milks were prepared;

2. subject: total 280, 140 males, 140 females, age 25-35 years, composite volunteer enrollment criteria for subjects, randomized into 14 groups of 20 each of 10 males, 10 females;

3. the spot test method comprises the following steps: selecting a qualified spot tester, applying about 0.02-0.025 mL of the essence milk prepared in examples 1-7 to the curved side of the forearm of 1-7 groups of subjects by a closed class test method, removing the test substances after 24 hours, observing skin reaction 30 minutes after the spot tester of the test substances is removed and after the indentation disappears, recording the result according to the skin reaction grading standard in the cosmetic hygiene Specification (2007 edition), and recording the reaction result in Table 3 according to the skin adverse reaction grading standard in Table 2 by the same operation method, wherein the essence milk prepared in comparative examples 1-7 is applied to the curved side of the forearm of 8-14 groups of subjects.

TABLE 2 grading Standard of adverse skin reactions

Table 3 results of the skin patch test of the essential milks of examples 1 to 7 and comparative examples 1 to 7 on human body

As shown in the data in table 3, after the essential milks prepared in examples 1 to 7 were applied to the side of the arm, the skin of 20 subjects showed all negative reactions, and the grade was 0, and the essential milks prepared in examples 1 to 7 did not cause any adverse reaction on the skin of the human body according to the judgment standard of the skin patch test for human body in the cosmetic hygiene code (2007 edition).

In comparative example 2, because the hydroxyethylpiperazine ethanesulfonic acid is not added, 1 subject has a grade 1 reaction after the essence milk prepared in comparative example 2 is smeared, and because the essence milk without the hydroxyethylpiperazine ethanesulfonic acid is easily unbalanced in acid and alkali, the essence milk is harmful to human skin.

Second, wrinkle-removing and anti-aging efficacy test

The test method comprises the following steps: 280 female volunteers aged 40-55 years and often staying up all night are selected and divided into 14 groups of 20 persons, and the essence milks of examples 1-7 and comparative examples 1-7 are respectively eaten by the volunteers of each group, and the using method is as follows: after the face is cleaned with clear water in the morning and evening every day, the face is smeared once and is lightly pressed until the face is absorbed, the face wrinkles are observed after the face is continuously used for 30 days, the skin becomes obviously compact, the wrinkles are obviously reduced to be obvious, the face skin becomes obviously compact, the wrinkles are effectively reduced, the face skin is not improved to be ineffective, the wrinkle removing effect is shown in a table 4, and any other product is not used in the testing period.

Table 4 essential milk wrinkle-removing and anti-aging effects test prepared in examples 1 to 7 and comparative examples 1 to 7

As can be seen from the data in Table 4, the essence creams prepared in the examples 1 to 7 have more effective people and good wrinkle-removing and anti-aging effects and can make the facial skin firmer after being used for 30 consecutive days.

When the carnosine liquid, the hydroxyethyl piperazine ethanesulfonic acid, the squalane, the compound fruit acid extract, the yerba mate tea extract, the ginseng root extract and the yeast lysate extract are not added into the essence milk, the wrinkle-removing effect of the essence milk is obviously reduced, which indicates that the anti-wrinkle effect of the essence milk can be obviously improved by adding the carnosine liquid, the hydroxyethyl piperazine ethanesulfonic acid, the squalane, the compound fruit acid extract, the yerba mate tea extract, the ginseng root extract and the yeast lysate extract into the essence milk.

Third, detection of effect of improving elasticity and moisture value

1. The test method comprises the following steps: selecting 240 female volunteers with poor skin elasticity and poor tightness, randomly dividing the female volunteers into 14 groups, coating the female volunteers with clear water to clean faces in the morning and evening every day, lightly pressing the female volunteers to absorb the essence milk prepared in the examples 1-7 and the comparative examples 1-7, continuously using the female volunteers for 4 weeks without using any product, performing batch elasticity analysis on the female volunteers every week, and recording results of 1 week, 2 weeks, 3 weeks and 4 weeks after use before use;

2. and (3) testing environment: the volunteers were cleaned and washed before testing, and the test was performed after waiting 30min in an environment with a temperature of 25 + -4 ℃ and a relative humidity of 48 + -5% RH, using a skin elasticity tester MPA580 (German CK) to detect the elasticity index R2 of the fixed area, using a German DJM skin tester to detect the moisture value of the skin, averaging the detected values of the elasticity value and the moisture value of each group of volunteers, and the detection results were recorded in Table 5.

Table 5 measurement of elasticity improvement and moisture content of essential milks prepared in examples 1 to 7 and comparative examples 1 to 7

As can be seen from the data in Table 5, the essential emulsions prepared in examples 1 to 7 have significantly increased skin elasticity and moisture value when applied, which indicates that the essential emulsions of the present invention have significant moisturizing effect on facial skin, can rapidly permeate into skin cells to moisturize skin, prevent loss of moisture and nutrients, and improve facial elasticity.

The essence emulsions prepared in comparative examples 1 to 7 have a slow increase in the elasticity value of the skin and an insignificant increase in the moisture content after application, which indicates that the essence emulsions prepared without the addition of carnosine liquid, hydroxyethylpiperazineethanesulfonic acid, squalane, complex fruit acid extract, yerba mate tea extract, ginseng root extract and yeast lysate extract have insignificant effects of improving the moisture and elasticity of the skin.

Fourth, testing the whitening efficacy

1. 280 female volunteers aged 18 to 50 were selected and randomly divided into 14 groups of 20 persons each, and after cleansing the face in the morning and evening, the facial film of the essence milk prepared in examples 1 to 7 and comparative examples 1 to 7 was applied to the face, the essence milk was absorbed by gentle pressure and continuously used for 30 days without using any other product during the test period, the melanin content of the facial skin of the volunteers (mean value of each group) was measured 1 day before using the product and 30 days after continuously using the product under the environment of ambient temperature 25 ± 4 ℃ and relative humidity 48 ± 5% RH using a memameter MX16 skin pigment analyzer, and the melanin inhibition rate (melanin content after using the black pigment before 1 day-melanin content after using 30 days)/melanin content before 1 day x 100% melanin before using the essence milk prepared in examples 1 to 7 was measured as shown in table 6, the serum milks prepared in comparative examples 1 to 7 were tested to obtain melanin inhibiting rates as shown in Table 7.

Table 6 whitening effect test results of the essential milks prepared in examples 1 to 7

As can be seen from the data in Table 6, the essence milks prepared in examples 1 to 7 have a good melanin inhibiting effect, and can inhibit the yellow and dark complexion of the face and prevent the deposition of melanin.

Table 7 whitening effect test results of the essential milks prepared in comparative examples 1 to 7

As can be seen from the data in table 7, the serum prepared without adding carnosine liquid, hydroxyethylpiperazine ethanesulfonic acid, squalane, complex fruit acid extract, yerba mate tea extract, ginseng root extract and yeast lysate extract has a significantly reduced melanin inhibiting ability, indicating that the addition of carnosine liquid, hydroxyethylpiperazine ethanesulfonic acid, squalane, complex fruit acid extract, yerba mate tea extract, ginseng root extract and yeast lysate extract synergistically improves the whitening effect of the serum.

The present embodiment is only for explaining the present invention, and it is not limited to the present invention, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present invention.

Claims

1. The essence milk for improving the anti-saccharification effect of skin is characterized by consisting of a phase A, a phase B and a phase C, wherein the phase A consists of the following components in parts by weight: 50.21-55.21 parts of deionized water, 3-10 parts of glycerol, 2-8 parts of butanediol, 0.02-0.25 part of hydrolyzed sodium hyaluronate, 0.3-3 parts of carnosine liquid, 0.05-2 parts of 1, 2-pentanediol, 0.01-2 parts of tranexamic acid, 0.01-1 part of carbomer, 0.01-0.5 part of sclerotium rolfsii, 0.001-0.3 part of disodium EDTA, 0.2-2 parts of hydroxyethyl piperazine ethane sulfonic acid and 0.2-2 parts of nicotinamide;

2. The essence for improving skin anti-glycation effect according to claim 1, wherein the phase A consists of the following components in parts by weight: 51.21-53.21 parts of deionized water, 5-7 parts of glycerol, 4-7 parts of butanediol, 0.08-0.15 part of hydrolyzed sodium hyaluronate, 0.5-1.5 parts of carnosine liquid, 0.2-1.5 parts of 1, 2-pentanediol, 0.15-1 part of tranexamic acid, 0.05-0.1 part of carbomer, 0.1-0.3 part of sclerotium rolfsii, 0.01-0.1 part of EDTA disodium, 0.5-1.5 parts of hydroxyethyl piperazine ethane sulfonic acid and 0.5-1.5 parts of nicotinamide;

3. The essence emulsion for improving the anti-glycation effect of the skin according to any one of claims 1-2, characterized in that the compound fruit acid extracting solution is prepared by mixing the following components in parts by weight: 74-76 parts of water, 4-5 parts of sugarcane extract, 5-6 parts of vaccinium myrtillus extract, 4-5 parts of sweet orange fruit extract, 5-6 parts of maple extract and 4-5 parts of citron fruit extract.

4. The essence lotion for improving skin anti-glycation effect according to any one of claims 1-2, characterized in that the carnosine liquid is prepared by mixing the following components in parts by weight: 4.5-5.5 parts of carnosine, 4.5-5.5 parts of pentanediol and 89-91 parts of glycerol.

5. The essence milk for improving skin anti-glycation efficacy according to any one of claims 1-2, wherein the extract of the Adansonia dubia fruit flesh is prepared by mixing the following components in parts by weight: 97.9-98 parts of water, 0.8-1 part of Adansonia dubia pulp extract, 0.4-0.5 part of sodium benzoate, 0.3-0.35 part of xanthan gum and 0.4-0.5 part of potassium sorbate.

6. The essence for improving skin anti-saccharification effect according to any one of claims 1-2, wherein the chlorella extract is prepared by mixing the following components in parts by weight: 5.5-7.5 parts of chlorella extract, 1.5-2.5 parts of pentanediol, 1.8-2.2 parts of 1, 2-hexanediol, 5.5-6.5 parts of butanediol and 82-84 parts of water.

7. The essence lotion for improving skin anti-glycation efficacy according to any one of claims 1-2, wherein the yeast lysate extracting solution is prepared by mixing water and yeast lysate extract in a mass ratio of 7-7.5: 2.5-3;

8. The essence for improving skin anti-glycation effect according to any one of claims 1-2, wherein the palmitoyl hexapeptide-12 liquid is prepared by mixing the following components in parts by weight: 20-25 parts of glycerol polymethacrylate, 74.5-79.9 parts of polyethylene glycol-8 and 0.1-0.5 part of palmitoyl hexapeptide-12;

9. The essence lotion for improving skin anti-glycation effect according to any one of claims 1-2, characterized in that the ginseng root extract is prepared by mixing ginseng root extract, water and butanediol in a mass ratio of 0.1:14.9-15: 5; the grape seed extract is prepared by mixing grape seed extract, water and butanediol with the mass ratio of 0.1:14.9-15: 5; the yerba mate tea extract is prepared by mixing yerba mate tea extract, water and butanediol in a mass ratio of 0.1:14.9-15: 5; the purslane extracting solution is prepared by mixing the following components in parts by weight: 74.5-74.9 parts of water, 25 parts of butanediol and 0.1-0.5 part of purslane extract.

10. A method for preparing essence emulsion for improving skin anti-glycation efficacy according to any one of claims 1 to 9, characterized by comprising the following steps: