CN113456553B - Anti-aging and brightening composition and anti-aging and brightening essence containing monkey-bread tree pulp extract and preparation method thereof - Google Patents
Anti-aging and brightening composition and anti-aging and brightening essence containing monkey-bread tree pulp extract and preparation method thereof Download PDFInfo
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- CN113456553B CN113456553B CN202110861348.XA CN202110861348A CN113456553B CN 113456553 B CN113456553 B CN 113456553B CN 202110861348 A CN202110861348 A CN 202110861348A CN 113456553 B CN113456553 B CN 113456553B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention belongs to the technical field of beauty and skin care, and particularly relates to an anti-aging and brightening composition containing a monkey-bread tree pulp extract, an anti-aging and brightening essence and a preparation method thereof. The anti-aging and brightening composition containing the monkey-bread tree pulp extract comprises the following components: monkey pulp extract, palmitoyl tripeptide-1 and acetyl hexapeptide-8. The anti-aging and brightening composition containing the monkey bread tree pulp extract can strengthen skin barrier, help rebuilding skin tissue structure, reduce wrinkles and fine lines, and brighten skin, can be used as an additive to be applied to cosmetics, and can be prepared into cosmetics such as essence, cream, emulsion and the like by adding a common mechanism or carrier of skin care products.
Description
Technical Field
The invention belongs to the technical field of beauty and skin care, and particularly relates to an anti-aging and brightening composition containing a monkey-bread tree pulp extract, an anti-aging and brightening essence and a preparation method thereof.
Background
Monkey-type trees, also known as life-prolonging trees in africa, are a longevity tree species that are considered to survive over 2000. The monkey bread pulp extract mainly contains saccharides, grease, protein, cellulose and a large amount of vitamin C, and has very excellent antioxidant and anti-aging effects.
With the rapid development of society, more and more people want to pursue improvement of quality of life. People are increasingly concerned about the problems of aging and dullness of facial skin, and hope to solve the problems of aging and dullness of the facial skin by using an anti-aging product. Therefore, the production of a safe product with the functions of anti-aging and brightening is very necessary.
Disclosure of Invention
Aiming at the related technical requirements, the invention provides an anti-aging and brightening composition containing the monkey-bread tree pulp extract, which can strengthen skin barrier, help rebuilding skin tissue structure, reduce wrinkles and fine lines and lighten skin.
In order to achieve the above purpose, the invention adopts the following technical scheme:
an anti-aging and lightening composition comprising a monkey-bread tree pulp extract comprising the following components: monkey pulp extract, palmitoyl tripeptide-1 and acetyl hexapeptide-8.
In the invention, the anti-aging and brightening component is a main functional additive. Wherein:
the monkey bread pulp extract mainly contains saccharides, grease, protein, cellulose and a large amount of vitamin C, and has very excellent antioxidant and anti-aging effects.
Palmitoyl tripeptide-1 is a highly specific, biologically active small molecule peptide. Can penetrate dermis, stimulate proliferation of collagen, elastic fiber and hyaluronic acid, promote water content and water locking degree of skin, increase skin thickness and reduce fine lines.
Acetyl hexapeptide-8 is a bioactive polypeptide that reduces muscle contraction by inhibiting release of the neurotransmitter acetylcholine, thereby reducing the production of dynamic and expressive lines. Acetyl hexapeptide-8 can both reduce existing facial wrinkles and effectively prevent new wrinkles from occurring.
The anti-aging and brightening composition containing the monkey bread tree pulp extract can strengthen skin barrier, help rebuilding skin tissue structure, reduce wrinkles and fine lines, and brighten skin, can be used as an additive to be applied to cosmetics, and can be prepared into cosmetics such as essence, cream, emulsion and the like by adding a common mechanism or carrier of skin care products.
Preferably, the anti-aging and brightening composition containing the monkey-bread tree pulp extract comprises the following components: monkey pulp extract aqueous solution (5%), palmitoyl tripeptide-1 aqueous solution (100 ppm), acetyl hexapeptide-8 aqueous solution (500 ppm).
Preferably, the anti-aging and brightening composition containing the monkey-bread tree pulp extract comprises the following components in parts by weight: 5-25 parts of a water solution (5%) of a pulp extract of the monkey tree, 1 part of a water solution (100 ppm) of palmitoyl tripeptide-1, 1 part of a water solution (500 ppm) of acetyl hexapeptide-8, and the balance of water.
A preparation comprising the anti-aging and brightening composition according to any of the preceding claims, wherein the preparation comprises 0.1 to 10wt% of the anti-aging and brightening composition. The product is selected from skin care products or cosmetics such as essence, face cream, eye cream, emulsion, etc.
The invention also discloses an anti-aging and brightening essence, which comprises the following components in parts by weight:
A. 0-10 parts of the anti-aging lightening composition of any one of claims 1-3;
B. oil phase component:
0.5-1.5 parts of hydrogenated lecithin,
1.25-2.5 parts of cyclomethicone,
1.25-2.5 parts of polydimethylsiloxane;
F. aqueous phase component:
1-5 parts of glycerin,
1-1.5 parts of 1, 2-butanediol,
1-2 parts of pentanediol,
EDTA disodium 0.05 part,
0.1 to 0.3 part of sodium acrylate/sodium acryloyldimethyl taurate copolymer,
1 to 1.5 parts of betaine,
0.15 part of carbomer,
The balance of water;
G. a neutralizer component:
0.1-0.5 part of triethanolamine;
H. auxiliary components:
0.5 part of phenoxyethanol,
0.1 part of essence.
The invention also discloses a preparation method of the anti-aging and brightening essence, which comprises the following steps:
(1) Heating the phase C to 80 ℃, preserving heat to 80 ℃, and stirring and dissolving completely;
(2) Heating the phase B to 80 ℃, and stirring and dissolving completely;
(3) Pumping the C phase into an emulsifying pot, slowly pumping the B phase, homogenizing for 5 minutes, preserving heat, stirring for 10 minutes, vacuumizing and cooling;
(4) Adding phase D when the temperature is reduced to 55 ℃, homogenizing for 3 minutes, and uniformly stirring;
(5) Adding A, E phase when the temperature is reduced to 50 ℃, preserving heat and stirring for 3 minutes, and vacuumizing and reducing the temperature;
(6) Cooling to 35 ℃ to obtain the anti-aging and brightening essence.
Advantageous effects
The invention discloses an anti-aging and brightening composition containing a monkey-bread tree pulp extract, which can effectively remove excessive free radicals in a body, strengthen skin barriers, help tissue structure reconstruction, ease wrinkles, remove melanin and strengthen skin. The composition has natural safety components, and can not cause irritation and adverse reaction to skin. In addition, the formulation of the anti-aging and brightening composition containing the pulp of the monkey-bread tree is not limited, and the composition can be applied to all types of cosmetics and skin care products such as face cream, essence, emulsion and the like.
Detailed Description
Hereinafter, the present invention will be described in detail. Before the description, it is to be understood that the terms used in this specification and the appended claims should not be construed as limited to general and dictionary meanings, but interpreted based on the meanings and concepts corresponding to technical aspects of the present invention on the basis of the principle that the inventor is allowed to define terms appropriately for the best explanation. Accordingly, the description set forth herein is merely a preferred example for the purpose of illustration and is not intended to limit the scope of the invention, so that it should be understood that other equivalents or modifications may be made thereto without departing from the spirit and scope of the invention.
The following examples are merely illustrative of embodiments of the present invention and are not intended to limit the invention in any way, and those skilled in the art will appreciate that modifications may be made without departing from the spirit and scope of the invention. Unless otherwise specified, reagents and equipment used in the following examples are commercially available products.
Example 1
An anti-aging and brightening composition containing a monkey-bread tree pulp extract comprises the following components in parts by mass: 5 parts of 5% aqueous solution of a pulp extract of the monkey tree, 1 part of an aqueous solution of palmitoyl tripeptide-1 (100 ppm), 1 part of an aqueous solution of acetyl hexapeptide-8 (500 ppm) and the balance of water.
Example 2
An anti-aging and brightening composition containing a monkey-bread tree pulp extract comprises the following components in parts by mass: 10 parts of 5% aqueous solution of a pulp extract of the Chinese mugwort, 1 part of an aqueous solution of palmitoyl tripeptide-1 (100 ppm), 1 part of an aqueous solution of acetyl hexapeptide-8 (500 ppm) and the balance of water.
EXAMPLE 3 parts
An anti-aging and brightening composition containing a monkey-bread tree pulp extract comprises the following components in parts by mass: 15 parts of 5% aqueous solution of a pulp extract of the monkey tree, 1 part of palmitoyl tripeptide-1 (100 ppm), 1 part of acetyl hexapeptide-8 (500 ppm) and the balance of water.
Example 4
An anti-aging and brightening composition containing a monkey-bread tree pulp extract comprises the following components in parts by mass: 20 parts of 5% aqueous solution of a pulp extract of the Chinese mugwort, 1 part of palmitoyl tripeptide-1 (100 ppm), 1 part of acetyl hexapeptide-8 (500 ppm) and the balance of water.
Example 5
An anti-aging and brightening composition containing a monkey-bread tree pulp extract comprises the following components in parts by mass: 25 parts of 5% aqueous solution of a pulp extract of the monkey tree, 1 part of palmitoyl tripeptide-1 (100 ppm), 1 part of acetyl hexapeptide-8 (500 ppm) and the balance of water.
Example 6
Essence 1-8 containing the anti-aging and brightening composition provided by the invention is prepared, and the raw material components and weight percentages of the essence are shown in table 1.
TABLE 1 composition table of anti-aging and lightening essences 1-8
Experimental example 1 DPPH radical scavenging test
Preparing 0.01mg/mL aqueous solution of anti-aging and brightening essence 1-8 prepared in example 6 by deionized water respectively, transferring 2mL into a 10mL test tube with a plug, taking 0.15g DPPH (1, 1-diphenyl-2-trinitrophenylhydrazine) powder, taking 1000mL ethanol to prepare a solution, uniformly mixing, stirring for 12 hours at the normal temperature of 250rpm under the dark condition, taking 2mL DPPH solution into the test tube with the plug, standing at room temperature for 30min, and measuring absorbance A with the wavelength of 517nm by a spectrophotometer 517 The method comprises the steps of carrying out a first treatment on the surface of the At the same time, absorbance A of the 2mL solution dissolved in the example was measured after mixing with 2mL ethanol 0 Absorbance C of 2mL of water mixed with 2mL of DPPH ethanol solution and absorbance C of 2mL of water mixed with 2mL of ethanol solution 0 . Three replicates were measured and averaged to calculate radical scavenging according to the following formula, the greater the scavenging, the greater the antioxidant capacity of the examples.
DPPH radical clearance (%) = [ (a) 517 -A 0 )/(C-C 0 )]×100％
The results are shown in Table 2.
TABLE 2 test results of DPPH radical scavenger of anti-aging and brightening essence
As can be seen from table 2, of the anti-aging and whitening essence prepared in example 6, anti-aging and whitening essence 4 had the best DPPH radical scavenging rate, i.e., the best antioxidant effect. The optimal addition amount of the anti-aging and brightening composition in cosmetics is 6wt% through the DPPH free radical scavenging rate results of the anti-aging and brightening essence 4, 6 and 7, and the anti-aging and brightening essence 8 is prepared by only basic components, and has no obvious DPPH free radical scavenging effect.
Experimental example 2 wrinkle removal test
Group of subjects: 70 healthy female volunteers aged between 30 and 50 years are equally divided into seven groups according to the ages, 10 people in each group have an average age of 35+/-3 years.
The experimental method comprises the following steps: anti-aging and lightening essences 1-8 prepared in example 6 (in an amount of about 1 mL) were used in the canthus and tail area; the preparation is used for 4 weeks in the morning and evening. The depth and length reduction of wrinkles and fine lines in the canthus herring tail area were evaluated using the facial imaging system Vi sia-CR, and the results are shown in table 3.
TABLE 3 wrinkle test results record Table
From the test results, table 3 shows that the resulting anti-aging whitening essence 4 exhibited the highest reduction in wrinkles and fine lines in the anti-aging whitening composition configured in example 6. The anti-aging and brightening essence provided by the invention can be obtained through the results of the anti-aging and brightening essence 4, 6 and 7, and the optimal addition amount of the anti-aging and brightening essence in cosmetics is 6wt%. After the anti-aging and brightening essence provided by the invention is continuously used, the number of wrinkles and fine lines can be obviously reduced, and the skin aging is delayed.
Experimental example 3 skin lightening experiment
The skin color difference test probe and the multifunctional skin test system (CL 400 and MPA 9) are adopted to test the change of the brightness ITA degree of the skin before and after the anti-aging and brightening essence prepared by the invention is used, the ITA degree is the individual type angle of the skin, and the test of the brightness of the characterization skin is related to L, a and b. The greater the ITA DEG value, the brighter the skin; conversely, the darker the skin.
Group of subjects: the test person required the same experimental example 2.
The experimental results are shown in table 4.
TABLE 4 skin lightening Change recording Table
As can be seen from table 4, the anti-aging and brightening essence 4 has an optimal brightening effect on skin brightness, and when the anti-aging and brightening composition prepared in example 4 is prepared in the essence at a higher concentration, the obtained brightening effect is obvious, but adverse reactions such as allergy occur to the tested population, and the proportion of the anti-aging and brightening composition in the anti-aging and brightening essence should be properly reduced for safety.
The above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be apparent to one skilled in the art that modifications may be made to the technical solutions described in the foregoing embodiments, or equivalents may be substituted for some of the technical features thereof; such modifications and substitutions do not depart from the spirit and scope of the corresponding technical solutions.
Claims (2)
1. An anti-aging and brightening essence is characterized by comprising the following components in percentage by weight:
A. 6wt% of an anti-aging and brightening composition;
B. oil phase component:
hydrogenated lecithin 0.5-wt%,
2.5. 2.5 wt% of cyclomethicone,
Polydimethylsiloxane 2.5. 2.5 wt%;
C. aqueous phase component:
glycerin 1.5. 1.5 wt%,
1, 2-butanediol 1 wt%,
Pentanediol 1.5. 1.5 wt%,
EDTA disodium 0.05 wt%,
Sodium acrylate/sodium acryloyldimethyl taurate copolymer 0.2. 0.2 wt%,
Betaine 1 wt percent,
0.15% carbomer wt%,
The balance of water;
D. a neutralizer component:
triethanolamine 0.3 wt%;
E. auxiliary components:
0.5 percent wt percent of phenoxyethanol,
Essence 0.1 wt%;
the anti-aging and brightening composition comprises the following components in parts by weight: 20 parts of 5% monkey bread tree pulp extract aqueous solution, 1 part of 100ppm palmitoyl tripeptide-1 aqueous solution, 1 part of 500ppm acetyl hexapeptide-8 aqueous solution and the balance of water.
2. The method for preparing anti-aging and brightening essence according to claim 1, comprising the following steps of
The method comprises the following steps:
(1) Heating the phase C to 80 ℃, preserving heat to 80 ℃, and stirring and dissolving completely;
(2) Heating the phase B to 80 ℃, and stirring and dissolving completely;
(3) Pumping the C phase into an emulsifying pot, slowly pumping the B phase, homogenizing for 5 minutes, preserving heat, stirring for 10 minutes, vacuumizing and cooling;
(4) Adding phase D when the temperature is reduced to 55 ℃, homogenizing for 3 minutes, and uniformly stirring;
(5) Adding A, E phase when the temperature is reduced to 50 ℃, preserving heat and stirring for 3 minutes, and vacuumizing and reducing the temperature;
(6) Cooling to 35 ℃ to obtain the anti-aging and brightening essence.
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