CN112791040B - Anti-wrinkle composition containing sturgeon caviar extract, preparation method and application thereof - Google Patents
Anti-wrinkle composition containing sturgeon caviar extract, preparation method and application thereof Download PDFInfo
- Publication number
- CN112791040B CN112791040B CN202110175710.8A CN202110175710A CN112791040B CN 112791040 B CN112791040 B CN 112791040B CN 202110175710 A CN202110175710 A CN 202110175710A CN 112791040 B CN112791040 B CN 112791040B
- Authority
- CN
- China
- Prior art keywords
- percent
- wrinkle
- phase
- aqueous solution
- sturgeon caviar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to an anti-wrinkle composition containing sturgeon caviar extract, which comprises the following components: sturgeon caviar extract, palmitoyl pentapeptide-4 and acetyl hexapeptide-8; and an essence containing the anti-wrinkle composition and a preparation method thereof. The sturgeon caviar extract, the palmitoyl pentapeptide-4 and the acetyl hexapeptide-8 have a synergistic effect on wrinkle resistance; meanwhile, by adjusting the proportion of each functional component and limiting the content of the composition in the cosmetics, the anti-wrinkle effect of the cosmetic is ensured, and the safety of the product is ensured.
Description
Technical Field
The invention relates to an anti-wrinkle composition containing sturgeon caviar extract, a preparation method and application thereof, and belongs to the technical field of anti-wrinkle.
Background
With the increasing demand for quality of life, people pay more and more attention to the aging problem of skin and the repair and maintenance work thereof, and hope to alleviate the facial wrinkle problem by using related anti-wrinkle products.
At present, anti-wrinkle products in the market are various in types, such as antioxidants, plant or Chinese herbal medicine antioxidant active ingredients and the like. The product quality is good and uneven, and the product effect is uneven.
The sturgeon caviar extract mainly contains various proteins, fatty acids, vitamins and pantothenic acid. The collagen elastic net can penetrate into a skin cell internal protection system to prolong the service life of skin cells, and simultaneously, the collagen elastic net can effectively synthesize, excite and repair the collagen elastic net of the skin and improve skin wrinkles caused by factors such as age, environment and the like similar to the protein components forming deep skin.
The sturgeon caviar extract has a limited addition amount in the cosmetic, and thus has a limited anti-wrinkle effect. In order to achieve the expected anti-wrinkle effect, the anti-wrinkle composition needs to be compounded with other functional components with anti-wrinkle activity. There is a need to develop an anti-wrinkle cosmetic composition with reasonable formulation and safety and efficacy.
Disclosure of Invention
The invention provides an anti-wrinkle composition containing sturgeon caviar extract, a preparation method and application, wherein the sturgeon caviar extract, palmitoyl pentapeptide-4 and acetyl hexapeptide-8 have a synergistic effect on resisting wrinkles; the components of the invention are preferably sturgeon caviar extract aqueous solution, palmitoyl pentapeptide-4 aqueous solution and acetyl hexapeptide-8 aqueous solution; by adjusting the proportion of each functional component and limiting the content of the composition in the cosmetics, the anti-wrinkle effect of the cosmetic is ensured, and the safety of the product is ensured. The technical scheme of the invention is as follows:
an anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass:
0.1-20 parts of sturgeon caviar extract aqueous solution (1 wt%), 0.05-0.8 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 0.05-0.8 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
The anti-wrinkle composition containing the sturgeon caviar extract has good skin permeability, can help skin tissue structure reconstruction and reduce fine lines, and can be applied to cosmetics as an additive. Adding conventional mechanisms or carriers of skin care products, and making into cosmetic such as essence, cream, eye cream, and lotion. The dosage of the anti-wrinkle composition containing the sturgeon caviar extract is 0.05-5wt% of the total mass of the cosmetic according to the mass percentage.
Further, the invention also comprises an anti-wrinkle essence which comprises the following components in percentage by mass:
phase A, firming and anti-wrinkle component
Anti-wrinkle composition containing sturgeon caviar extract 0.05-5%,
B phase and oil phase components
0.25 to 1 percent of hydrogenated lecithin,
1.25 to 5 percent of cyclopolydimethylsiloxane,
C phase and water phase components
The balance of water (to 100 percent),
0.5 to 5 percent of glycerin,
1,2-butanediol 0.5-1.5%,
0.5 to 1.5 percent of pentanediol,
0.01 to 0.03 percent of EDTA disodium,
0.1-0.3% of sodium acrylate/sodium acryloyldimethyl taurate copolymer,
1.5 to 2.5 percent of betaine,
0.1 to 0.5 percent of carbomer,
Phase D, neutralizer component
0.1 to 0.5 percent of triethanolamine,
E phase, auxiliary agent component
0.01 to 0.1 percent of essence,
0.1 to 0.5 percent of preservative.
The preparation method of the anti-wrinkle essence comprises the following steps:
(1) Heating the phase C to 75 ℃, keeping the temperature to 75 ℃, and stirring to dissolve completely;
(2) Heating the phase B to 75 ℃, and stirring to dissolve completely;
(3) Pumping the phase C into an emulsifying pot, slowly pumping the phase B into the emulsifying pot, homogenizing for 5 minutes, preserving heat, stirring for 10 minutes, and vacuumizing for cooling;
(4) Cooling to 60 deg.C, adding phase D, homogenizing for 3 min, and stirring;
(5) Cooling to 45 deg.C, adding A, E phase, stirring for 3 min, and vacuumizing to cool;
(6) Cooling to 30 ℃ to obtain the anti-wrinkle essence.
In the invention, the firming and anti-wrinkle component is a main functional additive. Wherein:
the sturgeon caviar extract is prepared from roe of sturgeon, and contains trace elements, vitamins, proteins, amino acids and unsaturated fatty acids. Suitable sturgeon Caviar extracts may include, but are not limited to, caviar Hydroglycolic Extract (300130) (from Baihaobo Biotech, inc., shanghai).
The sturgeon caviar extract can provide skin with moisturizing, nourishing, antiaging, vitamin supplementing and protecting effects, and can help skin reverse aging process. Carbohydrates can preserve moisture, proteins can provide nourishment, high content of unsaturated fatty acids can moisten dry and aged skin, vitamins and trace elements can restore skin vitality.
Palmitoyl pentapeptide-4 is a highly specific, biologically active small molecule peptide. Can penetrate dermis, stimulate proliferation of collagen, elastic fiber and hyaluronic acid, increase water content and water locking degree of skin, increase skin thickness and reduce fine lines.
Acetyl hexapeptide-8 is a bioactive polypeptide that reduces muscle contraction by inhibiting the release of the neurotransmitter acetylcholine, thereby achieving a reduction in the production of dynamic and expression striations.
The acetyl hexapeptide-8 can reduce the existing facial wrinkles and can effectively prevent the generation of new wrinkles.
Compared with the prior art, the invention has the following advantages:
according to the anti-wrinkle composition containing the sturgeon caviar extract, the sturgeon caviar extract and the two active polypeptides are compounded, so that the problem of facial wrinkles caused by skin aging can be effectively improved in multiple ways, the anti-oxidation capacity and the tissue structure reconstruction capacity of facial skin can be improved, the elasticity of the skin is improved, the skin metabolism is promoted, and the skin is kept young. The anti-wrinkle composition is natural and safe in components, and hardly has irritation and other adverse reactions to facial skin within a reasonable adding amount range. The anti-wrinkle composition containing the sturgeon caviar extract according to the present invention is not limited in formulation, and may be applied to cosmetics in all formulations such as cream, essence, and lotion.
Drawings
FIG. 1 is a graph showing the change of wrinkles around the eyes after using the anti-wrinkle essence of the present invention for 1-13,4 weeks;
FIG. 2 is a graph showing the changes in skin elasticity after 1-13,2 weeks and 4 weeks of use of the anti-wrinkle essence of the present invention;
FIG. 3 is a graph showing the effect of improving the face of a subject after 4 weeks using the anti-wrinkle essence of the present invention.
Detailed Description
The invention will be further described with reference to specific embodiments, and the advantages and features of the invention will become apparent as the description proceeds. The examples are illustrative only and do not limit the scope of the present invention in any way. It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention, and that such changes and substitutions are intended to be within the scope of the invention.
Example 1
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 10 parts of 1% aqueous solution of sturgeon caviar extract and 0.8 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm).
Example 2
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 10 parts of 1% aqueous solution of sturgeon caviar extract and 0.8 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
Example 3
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 10 parts of 1% aqueous solution of sturgeon caviar extract, 0.05 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 1.2 parts of acetyl hexapeptide-8 aqueous solution (700 ppm).
Example 4
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 10 parts of 1% aqueous solution of sturgeon caviar extract, 0.1 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 0.7 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
Example 5
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 10 parts of 1% aqueous solution of sturgeon caviar extract, 0.4 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 0.4 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
Example 6
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 10 parts of 1% aqueous solution of sturgeon caviar extract, 0.7 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 0.1 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
Example 7
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 10 parts of 1% aqueous solution of sturgeon caviar extract, 1.2 parts of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 0.05 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
Example 8
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 5 parts of 1% aqueous solution of sturgeon caviar extract, 0.7 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 0.1 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
Example 9
An anti-wrinkle composition containing sturgeon caviar extract comprises the following components in parts by mass: 20 parts of 1% aqueous solution of sturgeon caviar extract, 0.5 part of palmitoyl pentapeptide-4 aqueous solution (100 ppm) and 0.5 part of acetyl hexapeptide-8 aqueous solution (700 ppm).
Anti-wrinkle essence 1-13 containing the anti-wrinkle compositions according to examples 1-9 of the present invention was prepared using the raw material components and weight percentages shown in table 1.
TABLE 1 anti-wrinkle essence 1-13 ingredient Table
Experimental example 1 wrinkle removal test
The test population: 130 healthy female volunteers of 40-50 years of age with similar facial wrinkles were randomized to average 13 groups of 10 individuals each.
The experimental method comprises the following steps: applying anti-wrinkle essence 1-13 (about 1 mL) to the wrinkle area around eyes; it is administered in the morning and evening for 4 weeks. The number of wrinkles in the periocular wrinkle region and the degree of reduction in the area of wrinkles were evaluated using the facial imaging system Visia-CR, and the results are shown in table 2 and fig. 1.
TABLE 2 periocular wrinkle Change after 4 weeks Using samples
| Anti-wrinkle essence serial number | Average surface wrinkle reduction | Average surface |
| 1 | 10.3％ | 12.8％ |
| 2 | 12.6％ | 15.2％ |
| 3 | 21.8％ | 24.3％ |
| 4 | 23.5％ | 26.4％ |
| 5 | 20.7％ | 23.1％ |
| 6 | 18.1％ | 20.7％ |
| 7 | 16.8％ | 19.3％ |
| 8 | 14.7％ | 17.3％ |
| 9 | 19.8％ | 22.4％ |
| 10 | 11.7％ | 14.9％ |
| 11 | 17.3％ | 19.6％ |
| 12 | 26.3％ | 28.6％ |
| 13 | 27.8％ | 32.1％ |
In the test process, allergy phenomena are found to occur more in the subjects using the anti-wrinkle essence 12-13 with higher addition amount of the anti-wrinkle composition, and the content of the anti-wrinkle composition is recommended to be not more than 5% in consideration of the product safety.
As can be seen from the test results, the anti-wrinkle essence 4 prepared from the anti-wrinkle composition obtained in example 4 has the best anti-wrinkle effect, except for the anti-wrinkle essences 12 to 13, and the sturgeon caviar extract, palmitoyl pentapeptide-4 and acetyl hexapeptide-8 have the strongest synergistic effect on the anti-wrinkle effect at a reasonable compounding ratio.
According to the results, the anti-wrinkle essence 4 prepared in example 4 has safety and a significant wrinkle smoothing effect.
Experimental example 2 skin elasticity test
The test population: the test subjects required the same experiment 1.
The experimental method comprises the following steps: the anti-wrinkle essence 1-13 prepared in examples 1-9 (about 2-3mL in amount, based on a thin coating of face) was applied to the whole face area; it is administered in the morning and evening for 4 weeks. The forehead, chin and left and right cheek regions of the subject were tested using a skin elasticity tester (curometer MPA580 host machine, probe is revisometer RV600 elasto-fibrous tissue test probe), and the test results are shown in table 3 and fig. 2.
TABLE 3 skin elasticity Change after 2 and 4 weeks Using samples
When the test persons are revisited, the test persons using the anti-wrinkle essence 12-13 are found to have a large number of irritation reactions such as redness and swelling, allergy and the like, and considering the product safety, the addition amount of the anti-wrinkle composition provided by the invention is not too large and is controlled within 5%.
As can be seen from the test results, the anti-wrinkle essence 4 prepared in example 4 was most effective in increasing skin elasticity, except for anti-wrinkle essences 12 to 13, and no adverse reaction occurred in the human subjects. According to the invention, under a specific mixture ratio, the sturgeon caviar extract, palmitoyl pentapeptide-4 and acetyl hexapeptide-8 have a synergistic interaction effect, and can remarkably and continuously recover skin elasticity, as shown in figure 3.
Wherein, FIGS. 3-A and 3-B are photographs of the face of the subject before and after 4 weeks of use, respectively. As can be seen from the figure, after 4 weeks of use, the wrinkle problem of the facial skin of the subject is obviously improved, and the effects of brightening the skin color, tightening the skin and the like are achieved.
Claims (4)
1. The anti-wrinkle essence is characterized by comprising the following components in percentage by mass:
phase A, firming and anti-wrinkle component
Anti-wrinkle composition containing sturgeon caviar extract 0.05-5%; the anti-wrinkle composition comprises the following components in parts by mass: 0.1-20 parts of 1wt% sturgeon caviar extract water solution, 0.05-0.8 part of 100ppm palmitoyl pentapeptide-4 aqueous solution and 0.05-0.8 part of 700ppm acetyl hexapeptide-8 aqueous solution;
b phase and oil phase components
0.25 to 1 percent of hydrogenated lecithin,
1.25-5% of cyclic polydimethylsiloxane,
C phase and water phase components
The balance of water is made up to 100%,
0.5 to 5 percent of glycerin,
1,2-butanediol 0.5-1.5%,
0.5 to 1.5 percent of pentanediol,
0.01 to 0.03 percent of EDTA disodium,
0.1-0.3% of sodium acrylate/sodium acryloyldimethyl taurate copolymer,
1.5 to 2.5 percent of betaine,
0.1 to 0.5 percent of carbomer,
Phase D, neutralizer component
0.1 to 0.5 percent of triethanolamine,
E phase, auxiliary agent component
0.01 to 0.1 percent of essence,
0.1 to 0.5 percent of preservative.
2. The anti-wrinkle essence according to claim 1, wherein the anti-wrinkle composition comprises the following components in parts by mass:
10 parts of 1wt% sturgeon caviar extract aqueous solution, 0.1 part of 100ppm palmitoyl pentapeptide-4 aqueous solution and 0.7 part of 700ppm acetyl hexapeptide-8 aqueous solution.
3. The anti-wrinkle essence according to claim 1, which comprises the following components in percentage by mass:
anti-wrinkle composition containing sturgeon caviar extract 5%,
0.5 percent of hydrogenated lecithin,
2.5 percent of cyclopolydimethylsiloxane,
2 percent of glycerin,
1,2-butanediol 1%,
1 percent of pentanediol,
0.02 percent of EDTA disodium,
0.2 percent of sodium acrylate/sodium acryloyldimethyl taurate copolymer,
2 percent of betaine,
0.15 percent of carbomer,
0.15 percent of triethanolamine,
0.05 percent of essence,
0.3 percent of preservative.
4. The anti-wrinkle essence according to any one of claims 1 to 3, comprising the following specific steps:
(1) Heating the phase C to 75 ℃, keeping the temperature to 75 ℃, and stirring to dissolve completely;
(2) Heating the phase B to 75 ℃, and stirring to dissolve completely;
(3) Pumping the phase C into an emulsifying pot, slowly pumping the phase B into the emulsifying pot, homogenizing for 5 minutes, preserving heat, stirring for 10 minutes, and vacuumizing for cooling;
(4) Cooling to 60 deg.C, adding phase D, homogenizing for 3 min, and stirring;
(5) Cooling to 45 deg.C, adding A, E phase, stirring for 3 min, and vacuumizing to cool;
(6) Cooling to 30 ℃ to obtain the anti-wrinkle essence.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110175710.8A CN112791040B (en) | 2021-02-07 | 2021-02-07 | Anti-wrinkle composition containing sturgeon caviar extract, preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110175710.8A CN112791040B (en) | 2021-02-07 | 2021-02-07 | Anti-wrinkle composition containing sturgeon caviar extract, preparation method and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112791040A CN112791040A (en) | 2021-05-14 |
| CN112791040B true CN112791040B (en) | 2023-01-24 |
Family
ID=75814991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110175710.8A Active CN112791040B (en) | 2021-02-07 | 2021-02-07 | Anti-wrinkle composition containing sturgeon caviar extract, preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112791040B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113230198A (en) * | 2021-06-02 | 2021-08-10 | 上海佩威化妆品有限公司 | Anti-wrinkle anti-aging freeze-dried essence and preparation method thereof |
| CN113197785A (en) * | 2021-06-22 | 2021-08-03 | 杭州友丽医疗科技(集团)有限公司 | Anti-wrinkle and anti-redness regeneration composition, essence and preparation method thereof |
| CN113509429B (en) * | 2021-07-19 | 2023-11-03 | 加来(济南)生活科技有限公司 | Liposome anti-wrinkle composition containing sturgeon caviar extract, and preparation method and application thereof |
| KR102650644B1 (en) * | 2021-09-15 | 2024-03-26 | 코스맥스 주식회사 | Cosmetic composition comprising subcritical extract of plasma-treated caviar |
| CN114306095A (en) * | 2021-12-16 | 2022-04-12 | 中科(广州)再生医学科技开发有限公司 | Micro-needle patch for resisting wrinkles and preserving moisture and preparation method and application thereof |
| EP4272724A1 (en) * | 2022-05-04 | 2023-11-08 | La Prairie Group AG | Substance combination for cosmetic preparations |
| EP4272725A1 (en) * | 2022-05-04 | 2023-11-08 | La Prairie Group AG | Use of caviar extracts |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726668A (en) * | 2016-11-19 | 2017-05-31 | 诺斯贝尔化妆品股份有限公司 | A kind of many peptidoliposome raw materials used in cosmetics |
| CN108324676A (en) * | 2018-04-28 | 2018-07-27 | 广东巴松那生物科技有限公司 | A kind of promotion of compacting, anti-aging face cream and preparation method thereof |
| CN110664648A (en) * | 2019-10-16 | 2020-01-10 | 广州雅纯化妆品制造有限公司 | Caviar anti-aging composition |
| CN111214417A (en) * | 2020-03-10 | 2020-06-02 | 广州澳特朗生物技术有限公司 | Yeast essence with effects of tightening and resisting wrinkles and preparation method and application thereof |
-
2021
- 2021-02-07 CN CN202110175710.8A patent/CN112791040B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726668A (en) * | 2016-11-19 | 2017-05-31 | 诺斯贝尔化妆品股份有限公司 | A kind of many peptidoliposome raw materials used in cosmetics |
| CN108324676A (en) * | 2018-04-28 | 2018-07-27 | 广东巴松那生物科技有限公司 | A kind of promotion of compacting, anti-aging face cream and preparation method thereof |
| CN110664648A (en) * | 2019-10-16 | 2020-01-10 | 广州雅纯化妆品制造有限公司 | Caviar anti-aging composition |
| CN111214417A (en) * | 2020-03-10 | 2020-06-02 | 广州澳特朗生物技术有限公司 | Yeast essence with effects of tightening and resisting wrinkles and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN112791040A (en) | 2021-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112791040B (en) | Anti-wrinkle composition containing sturgeon caviar extract, preparation method and application thereof | |
| CN113648235B (en) | Composition for immediately removing wrinkles, eye mask essence, wrinkle-removing cosmetic and application | |
| CN111000748A (en) | Polypeptide repairing cream and preparation method thereof | |
| CN111450010A (en) | Composition with anti-aging effect and application thereof in cosmetics | |
| CN111904897A (en) | Nourishing type lip cosmetic and preparation method thereof | |
| CN112426401A (en) | Essence capable of tightening, tendering and brightening eyes and preparation method thereof | |
| CN115105453A (en) | Skin care product with antibacterial, anti-inflammatory and repairing functions and preparation method thereof | |
| CN110538093A (en) | polypeptide repair liquid and preparation method thereof | |
| CN111991286A (en) | Eye cream composition for fading fine wrinkles and preparation method thereof | |
| CN111557872A (en) | Skin care product of multi-oligopeptide composition | |
| CN109453102A (en) | A kind of compact recovery water of polypeptide face | |
| CN113081942A (en) | Multi-dimensional hydration cream containing apple stem cells | |
| CN112675060A (en) | Composition and skin care product for resisting skin aging and preparation method thereof | |
| CN112120949A (en) | Water-light moisturizing essence and preparation method thereof | |
| CN115414293B (en) | Anti-aging composition and application thereof | |
| CN116999378A (en) | Tightening and skin-brightening composition containing super-living pearl polypeptide mother liquor and preparation method thereof | |
| CN114796062B (en) | A composition and a compact anti-aging cosmetic | |
| CN111084742A (en) | Non-invasive skin care compositions for skin barrier repair | |
| CN114159333B (en) | Myobase liquid and preparation method thereof | |
| RU2456977C1 (en) | Dry and very dry skin care preparation | |
| CN114632045A (en) | Anti-aging composition, preparation method and application | |
| CN113456553A (en) | Anti-aging brightening composition and anti-aging brightening essence containing Paeonia suffruticosa pulp extract and preparation method thereof | |
| CN110664687B (en) | Skin-care type cleansing and makeup removing cream and preparation method thereof | |
| CN113662876A (en) | Polypeptide beautifying essence and preparation method thereof | |
| CN113069377A (en) | Anti-aging face cream and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |