CN111214417A - Yeast essence with effects of tightening and resisting wrinkles and preparation method and application thereof - Google Patents
Yeast essence with effects of tightening and resisting wrinkles and preparation method and application thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The invention belongs to the technical field of cosmetics, and discloses yeast essence with effects of tightening and resisting wrinkles and application of the yeast essence in cosmetics. The essence is prepared from the following raw materials: the yeast cell lysate comprises saccharomyces cerevisiae fermentation product lysate, rose water, glycerol, trehalose, carboxymethyl chitosan, sodium hyaluronate, hydrolyzed collagen, hydrolyzed oat protein, hydrolyzed yeast protein, glycerol stearate, acetyl hexapeptide-8, palmitoyl pentapeptide-4, snake venom tripeptide, dendrobium officinale extract, tremella extract, macadamia seed extract, camellia seed oil, tocopherol, macadamia seed oil, caprylyl glycol, phenoxyethanol, methyl hydroxybenzoate, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and the balance of water. The essence combines the lysate of the yeast fermentation product of the schizosaccharomyces and the polypeptide with the anti-wrinkle effect, and after the essence is used, the anti-aging effect, the wrinkle reduction effect and the skin vitality recovery effect can be achieved.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to yeast essence with effects of tightening and resisting wrinkles, and a preparation method and application thereof.
Background
At present, raw materials containing probiotic source functional components, such as staphylococcus epidermidis, Vitreoscilla transparentis, saccharomycetes and bifidobacteria or fermentation products thereof, appear in the cosmetic market, can improve the health of skin by regulating the microbial population of the skin, and have various skin care effects of diminishing inflammation, resisting oxidation, resisting wrinkles, repairing sensitive skin and the like. The lysate of the yeast fermentation products of the bifidus is a metabolite of bifidobacteria, and the attention of which in the cosmetic industry has been remarkably increased in recent years. There are many anti-aging products on the domestic market: face and eye tightening essence, cream, milk and the like, and few anti-aging products which can be trusted by customers and are really effective are available. Therefore, when the lysate of the yeast for secondary fission is used as the raw material with anti-wrinkle effect in skin care products, it becomes very important to develop safe products with anti-wrinkle effect.
Disclosure of Invention
In order to overcome the defects and shortcomings of the prior art, the invention aims to provide the yeast essence with the effects of tightening and resisting wrinkles, and the yeast essence not only has the effects of tightening and resisting wrinkles, but also has the effect of preserving moisture.
The invention also aims to provide a preparation method of the yeast essence with the effects of tightening and resisting wrinkles;
the invention further aims to provide application of the yeast essence with the effects of tightening and resisting wrinkles in cosmetics.
The purpose of the invention is realized by the following technical scheme:
the yeast essence with the effects of tightening and resisting wrinkles is prepared from the following raw materials in percentage by mass:
2 to 15 percent of yeast composite peptide composition, 5 to 10 percent of rose water, 1 to 8 percent of glycerin, 0.5 to 2 percent of trehalose, 0.5 to 1 percent of carboxymethyl chitosan, 0.02 to 0.2 percent of sodium hyaluronate, 1 to 3 percent of hydrolyzed collagen, 1 to 5 percent of hydrolyzed oat protein, 0.5 to 1 percent of hydrolyzed yeast protein, 0.1 to 1 percent of glycerin stearate, 0.3 to 10 percent of dendrobium officinale extract, 1 to 8 percent of tremella fuciformis extract, 1 to 3 percent of monkshood seed extract, 0.2 to 0.5 percent of camellia seed oil, 0.05 to 0.1 percent of tocopherol, 0.2 to 1 percent of monkey tree seed oil, 0.1 to 0.5 percent of octyl glycol, 0.1 to 0.5 percent of phenoxyethanol, 0.1 to 0.2 percent of methylparaben, 0.1 to 0.5 percent of hydroxyethyl acrylate/sodium acryloyldimethyl sulfonate copolymer, the balance of water; wherein the yeast complex peptide composition comprises 0.5% -10% of a split yeast fermentation product lysate, 0.5% -2% of acetyl hexapeptide-8, 0.5% -1.5% of palmitoyl pentapeptide-4, and 0.5% -1.5% of a snake venom-like tripeptide (dipeptide diaminobutyryl benzylamide diacetate).
Preferably, the yeast essence with the effects of tightening and resisting wrinkles is prepared from the following raw materials in percentage by mass:
2 to 14 percent of yeast composite peptide composition, 5 to 8 percent of rose water, 1 to 5 percent of glycerin, 0.5 to 1 percent of trehalose, 0.5 to 0.8 percent of carboxymethyl chitosan, 0.02 to 0.1 percent of low molecular sodium hyaluronate, 1 to 2.5 percent of hydrolyzed collagen, 1 to 5 percent of hydrolyzed oat protein, 0.8 to 1 percent of hydrolyzed yeast protein, 0.1 to 0.8 percent of glycerol stearate, 0.3 to 9 percent of dendrobium officinale extract, 3 to 8 percent of tremella extract, 1 to 2.5 percent of Adianthus tinus seed extract, 0.3 to 0.5 percent of camellia seed oil, 0.06 to 0.1 percent of tocopherol, 0.2 to 0.8 percent of Adianthus tinus seed oil, 0.1 to 0.5 percent of octyl glycol, 0.1 to 0.5 percent of ethanol, 0.1 to 0.2 percent of phenoxy methyl hydroxybenzoate, 0.1 to 0.3 percent of hydroxyethyl acrylate/dimethyl acryloyl copolymer, the balance of water; wherein the yeast complex peptide composition comprises 0.5% -9% of a split yeast fermentation product lysate, 0.5% -1.5% of acetyl hexapeptide-8, 0.5% -1.5% of palmitoyl pentapeptide-4, and 0.5% -2% of a snake venom-like tripeptide (dipeptide diaminobutyrylbenzylamide diacetate).
More preferably, the yeast essence with the effects of tightening and resisting wrinkles is prepared from the following raw materials in percentage by mass:
5 to 14 percent of yeast composite peptide composition, 6 to 8 percent of rose water, 2 to 5 percent of glycerin, 0.5 to 0.8 percent of trehalose, 0.6 to 0.8 percent of carboxymethyl chitosan, 0.03 to 0.1 percent of low molecular sodium hyaluronate, 1.5 to 2.5 percent of hydrolyzed collagen, 1.5 to 5 percent of hydrolyzed oat protein, 0.8 to 1 percent of hydrolyzed yeast protein, 0.2 to 0.8 percent of glycerol stearate, 0.5 to 9 percent of dendrobium officinale extract, 4 to 8 percent of tremella extract, 1.5 to 2.5 percent of Adiantum extract, 0.4 to 0.5 percent of camellia seed oil, 0.08 to 0.1 percent of tocopherol, 0.3 to 0.8 percent of Adiantum seed oil, 0.1 to 0.5 percent of octyl glycol, 0.1 to 0.5 percent of phenoxy ethanol, 0.1 to 0.2 percent of methylparaben, 0.1 to 0.3 percent of acrylic acid hydroxyethyl acrylate/dimethyl bovine acrylic acid sodium sulfonate, the balance of water; wherein the yeast complex peptide composition comprises 1.5% -8% of a split yeast fermentation product lysate, 1.5% -2% of acetyl hexapeptide-8, 1.5% -2% of palmitoyl pentapeptide-4, and 0.5% -2% of a snake venom-like tripeptide (dipeptide diaminobutyrylbenzylamide diacetate).
Most preferably, the yeast essence with the effects of tightening and resisting wrinkles is prepared from the following raw materials in percentage by mass:
14% of yeast composite peptide composition, 8% of rose water, 5% of glycerol, 0.8% of trehalose, 0.8% of carboxymethyl chitosan, 0.1% of low-molecular sodium hyaluronate, 2.5% of hydrolyzed collagen, 5% of hydrolyzed oat protein, 1% of hydrolyzed yeast protein, 0.5% of glycerol stearate, 9% of dendrobium officinale extract, 8% of tremella extract, 2.5% of monkey-tree seed extract, 0.5% of camellia seed oil, 0.1% of tocopherol, 0.8% of monkey-tree seed oil, 0.5% of octyl glycol, 0.5% of phenoxyethanol, 0.2% of methylparaben, 0.3% of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and the balance of water; wherein the yeast complex peptide composition comprises 9% split yeast fermentation product lysate, 1.5% acetyl hexapeptide-8, 1.5% palmitoyl pentapeptide-4, and 2% snake venom-like tripeptide (dipeptide diaminobutyrylbenzylamide diacetate).
A method for preparing the yeast essence with the effects of tightening and resisting wrinkles comprises the following steps:
respectively heating the component A and the component B to 75-85 ℃ for dissolving and dispersing; then adding the component B into the component A, stirring, homogenizing and dispersing completely, cooling to 45-55 ℃, sequentially adding the component C, the component D and the component E, and stirring uniformly; finally, cooling to below 38 ℃ and discharging; wherein the content of the first and second substances,
the component A comprises: glycerol, methylparaben, trehalose, carboxymethyl chitosan, sodium hyaluronate and water;
and B component: hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, glyceryl stearate, CAMELLIA (CAMELLIA JAPONICA) seed oil, tocopherol (vitamin E) and Adansonia DIGITATA (Adansonia DIGITATA) seed oil;
and C, component C: a yeast complex peptide composition;
and (D) component: tremella (Tremella FUCIFORMIS) extract and water, hydrolyzed collagen, 5% hydrolyzed oat protein and hydrolyzed yeast protein, herba Dendrobii (Dendrobium officinale (Dendrobii officinalis) stem extract), flos Rosae Rugosae (Rosa RUGOSA) flower water), and Herminium erinaceus seed extract (Adansonia digitorum seed extract);
and E, component (E): phenoxyethanol and caprylyl glycol;
wherein the water of the component A accounts for 80-98% of the total mass of the water.
The yeast essence with the effects of tightening and resisting wrinkles is applied to the preparation of cosmetics with the effects of tightening and resisting wrinkles.
The lysate of the yeast fermentation product in the yeast composite peptide composition is a physiological lysate obtained from bifidobacteria, and the functional components of the lysate comprise amino acid, nucleotide, monosaccharide, mineral, vitamin and other beneficial components, so that the lysate has the effects of accelerating the peeling of old cutin of skin and promoting the growth of new cells for resisting wrinkles and resisting aging. Acetyl hexapeptide-8: also called acetyl hexapeptide-3, hexapeptide is a commonly used anti-aging small peptide which is composed of 6 amino acids, and can reduce the contraction of muscles by inhibiting the release of neurotransmitter acetylcholine, thereby reducing the generation of expression lines; in addition, acetyl hexapeptide-8 can enhance the activity of skin collagen and elastin, relax facial expression, smooth wrinkles and improve skin laxity. Palmitoyl pentapeptide-4: is a bioactive peptide formed by dehydrating and condensing 5 amino acids, and has the functions of stimulating the generation of skin collagen, improving wrinkles and fine lines and better improving the anti-wrinkle capacity of the skin. A snake venom-like tripeptide: is a bionic small molecular tripeptide which is firstly found in the venom of the Temple Viper and is a muscle nicotinic acetylcholine receptor antagonist. It is safer and more effective than botulinum and has effective skin smoothing and wrinkle reducing activity. After the lysate of the yeast bifida ferment fermentation product in the yeast composite peptide composition firstly passes through the skin barrier repairing, the three polypeptides can reduce skin fine wrinkles and have the effects of tightening and resisting wrinkles.
Extract of Paeonia suffruticosa seeds: is rich in plant small molecular RNAs extracts, helps to improve and maintain skin homeostasis, reduces wrinkles, and improves skin self-moisturizing ability for up to 24 hours.
Camellia seed oil and tocopherol: tocopherol is an endogenous antioxidant present in fats and oils and is the most major constituent of vitamin E. The camellia seed oil added with tocopherol has the effects of scavenging free radicals, resisting oxidation, resisting bacteria and the like.
The invention provides a novel cosmetic additive for delaying skin aging, tightening and resisting wrinkles, which overcomes the defects in the prior art. The invention aims to accelerate the peeling of old cutin of skin, promote the proliferation of new cells, enhance the activity of collagen and elastin of skin, stimulate the rapid generation of collagen, improve the self moisturizing capability of skin, relax facial muscles and smooth skin to improve wrinkles and fine lines from the mechanism of skin wrinkle formation, meanwhile, the yeast compound peptide composition (lysate of a yeast fermentation product, acetyl hexapeptide-8, palmitoyl pentapeptide-4 and snake venom tripeptide), the moisturizing composition (hydrolyzed collagen, hydrolyzed oat protein, hydrolyzed yeast protein, dendrobium officinale extract, tremella extract and monkeytree seed extract), the camellia seed oil and the tocopherol are compounded to obtain the essence with better firming and anti-wrinkle effects. Not only the respective effects of the extracts are fully exerted, but also the synergistic effect is generated.
In addition, the invention also discloses application of the firming and anti-wrinkle yeast essence in cosmetics.
The invention has the following beneficial effects:
(1) the split yeast fermentation product lysate in the essence disclosed by the invention is derived from a probiotic fermentation product extraction process, is safe, has the effects of moisturizing, resisting wrinkles and soothing and repairing skin, is high in active ingredient content, and is mild and non-irritant when being applied to cosmetics.
(2) The essence disclosed by the invention selects the bioactive peptide as an active ingredient, is applied to series of anti-wrinkle effect skin care products, can effectively improve skin wrinkles and fine lines, smoothens skin, removes wrinkles, and achieves the effects of resisting wrinkles and ageing.
(3) The human body efficacy evaluation test-anti-wrinkle efficacy evaluation test method is adopted to analyze the anti-wrinkle efficacy of the essence, and the human body efficacy evaluation test method has very important significance for developing anti-wrinkle efficacy series products.
Drawings
FIG. 1 shows the change rate of moisture content of stratum corneum of example 4 after 2 weeks and 4 weeks using yeast essence and essence base.
FIG. 2 is a graph showing the change rate of skin moisture loss through skin after 2 weeks and 4 weeks using yeast essence and essence base in example 4.
Fig. 3 is a graph showing the change rate of skin firmness R0 after 2 and 4 weeks using yeast essence and essence base in example 4.
Fig. 4 shows the change rate of skin elasticity R2 after 2 and 4 weeks using the yeast essence and essence base in example 4.
Fig. 5 shows the change rate of the area ratio of the back wrinkles after 2 weeks and 4 weeks using the yeast essence and the essence base in example 4.
Detailed Description
The present invention will be described in further detail with reference to examples and drawings, but the embodiments of the present invention are not limited thereto. The reagents used in the examples are commercially available without specific reference.
The preparation method of the yeast essence with the effects of tightening and resisting wrinkles in the embodiment comprises the following steps: respectively heating the component A and the component B to 75-85 ℃ for dissolving and dispersing; then adding the component B into the component A, stirring, homogenizing and dispersing completely, cooling to 45-55 ℃, sequentially adding the component C, the component D and the component E, and stirring uniformly; finally, the temperature is reduced to normal temperature and the material is discharged.
Example 1:
the yeast essence with the effects of tightening and resisting wrinkles is prepared from the following components in percentage by mass: 13% yeast complex peptide composition, 5% rose water, 3% glycerol, 0.8% trehalose, 0.8% carboxymethyl chitosan, 0.1% low molecular sodium hyaluronate, 2.5% hydrolyzed collagen, 5% hydrolyzed oat protein, 1% hydrolyzed yeast protein, 0.5% glyceryl stearate, 9% dendrobium officinale extract, 8% tremella extract, 1.5% monkeytree seed extract, 0.5% camellia seed oil, 0.1% tocopherol, 0.8% monkeytree seed oil, 0.5% octyl glycol, 0.5% phenoxyethanol, 0.2% methylparaben, 0.3% hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, and the balance deionized water: wherein the water consumption of the component A is 80 percent. Wherein the yeast complex peptide composition comprises 8% split yeast fermentation product lysate, 1.5% acetyl hexapeptide-8, 1.5% palmitoyl pentapeptide-4, and 2% snake venom-like tripeptide (dipeptide diaminobutyrylbenzylamide diacetate).
Example 2:
the yeast essence with the effects of tightening and resisting wrinkles is prepared from the following components in percentage by mass: 14% yeast complex peptide composition, 6% rose water, 3% glycerol, 0.8% trehalose, 0.8% carboxymethyl chitosan, 0.1% low molecular sodium hyaluronate, 2.5% hydrolyzed collagen, 5% hydrolyzed oat protein, 1% hydrolyzed yeast protein, 0.5% glyceryl stearate, 9% dendrobium officinale extract, 8% tremella extract, 1.5% monkeytree seed extract, 0.5% camellia seed oil, 0.1% tocopherol, 0.8% monkeytree seed oil, 0.5% octyl glycol, 0.5% phenoxyethanol, 0.2% methylparaben, 0.3% hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, and the balance deionized water: wherein the water consumption of the component A is 83 percent. Wherein the yeast complex peptide composition comprises 9% split yeast fermentation product lysate, 1.5% acetyl hexapeptide-8, 1.5% palmitoyl pentapeptide-4, and 2% snake venom-like tripeptide (dipeptide diaminobutyrylbenzylamide diacetate).
Example 3:
the yeast essence with the effects of tightening and resisting wrinkles is prepared from the following components in percentage by mass: 15% yeast complex peptide composition, 8% rose water, 3% glycerol, 0.8% trehalose, 0.8% carboxymethyl chitosan, 0.1% low molecular sodium hyaluronate, 2.5% hydrolyzed collagen, 5% hydrolyzed oat protein, 1% hydrolyzed yeast protein, 0.5% glyceryl stearate, 9% dendrobium officinale extract, 8% tremella extract, 2% monkeytree seed extract, 0.5% camellia seed oil, 0.1% tocopherol, 0.8% monkeytree seed oil, 0.5% caprylyl glycol, 0.5% phenoxyethanol, 0.2% methylparaben, 0.3% hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, and the balance deionized water: wherein the water consumption of the component A is 88 percent. Wherein the yeast complex peptide composition comprises 10% split yeast fermentation product lysate, 1.5% acetyl hexapeptide-8, 1.5% palmitoyl pentapeptide-4, and 2% snake venom-like tripeptide (dipeptide diaminobutyrylbenzylamide diacetate).
Example 4:
15% yeast complex peptide composition, 8% rose water, 5% glycerol, 0.8% trehalose, 0.8% carboxymethyl chitosan, 0.1% low molecular sodium hyaluronate, 2.5% hydrolyzed collagen, 5% hydrolyzed oat protein, 1% hydrolyzed yeast protein, 0.5% glyceryl stearate, 9% dendrobium officinale extract, 8% tremella extract, 2.5% monkeytree seed extract, 0.5% camellia seed oil, 0.1% tocopherol, 0.8% monkeytree seed oil, 0.5% octyl glycol, 0.5% phenoxyethanol, 0.2% methylparaben, 0.3% hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, and the balance deionized water: wherein the water consumption of the component A is 98 percent. Wherein the yeast complex peptide composition comprises 10% split yeast fermentation product lysate, 2% acetyl hexapeptide-8, 1.5% palmitoyl pentapeptide-4, and 1.5% snake venom-like tripeptide (dipeptide diaminobutyrylbenzylamide diacetate).
The product of embodiment 4 of the invention has the following application effect tests:
specific test samples: the yeast essence and essence base of example 4. (Yeast essence refers to a formula system containing a yeast complex peptide composition as a core component; essence matrix refers to a formula system except the yeast complex peptide composition.)
The using method comprises the following steps: directly applying the prepared essence and essence matrix on face for 3-5 times per day.
The wrinkle resistance of the essence obtained by the invention is evaluated by adopting a special cosmetic efficacy evaluation method, and the result is as follows:
human body efficacy evaluation-anti-wrinkle efficacy evaluation test
The experimental method comprises the following steps: people (30-45 years old) with facial wrinkles are screened out to be used as anti-wrinkle efficacy test volunteers, after the face is coated with the essence obtained in the embodiment 4 of the invention through comparison of the essence and the essence substrate, the tests are respectively carried out in the 0 th week, the 2 nd week and the 4 th week, and the indexes (such as figures 1-5) of the skin moisture content, the skin moisture loss, the skin tightness, the skin elasticity, the wrinkle area and the like are measured, wherein the indexes are used for evaluating the skin barrier function and the effect of reducing the skin wrinkles after the product is used.
20 volunteers were recruited for the experiment, 20 active volunteers and the data was valid. The test was carried out for 4 weeks, and the differences of the skin moisture content, the skin moisture loss, the skin firmness, the skin elasticity and the wrinkle area were measured before and after the application of the sample, and the results are shown in fig. 1 to 5, respectively.
As a result: the moisture content of the horny layer of the skin on the side using the essence is better than that on the side using the essence substrate; the reduction degree of the percutaneous water loss of the skin on the side using the essence is better than that on the side using the essence substrate; the increase degree of the R0 value of the skin elasticity of the side using the essence is better than that of the side using the essence substrate; the increase degree of the R2 value of the skin elasticity of the side using the essence is better than that of the side using the essence substrate; the wrinkle ratio of the face using the essence is reduced to a better degree than that of the face using the essence substrate.
From the above results, it can be seen that the cosmetic prepared using the composition of the present invention can significantly reduce skin wrinkles and improve skin aging symptoms after 4 weeks.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (6)
1. The yeast essence with the effects of tightening and resisting wrinkles is characterized by being prepared from the following raw materials in percentage by mass:
2 to 15 percent of yeast composite peptide composition, 5 to 10 percent of rose water, 1 to 8 percent of glycerin, 0.5 to 2 percent of trehalose, 0.5 to 1 percent of carboxymethyl chitosan, 0.02 to 0.2 percent of sodium hyaluronate, 1 to 3 percent of hydrolyzed collagen, 1 to 5 percent of hydrolyzed oat protein, 0.5 to 1 percent of hydrolyzed yeast protein, 0.1 to 1 percent of glycerin stearate, 0.3 to 10 percent of dendrobium officinale extract, 1 to 8 percent of tremella fuciformis extract, 1 to 3 percent of monkshood seed extract, 0.2 to 0.5 percent of camellia seed oil, 0.05 to 0.1 percent of tocopherol, 0.2 to 1 percent of monkey tree seed oil, 0.1 to 0.5 percent of octyl glycol, 0.1 to 0.5 percent of phenoxyethanol, 0.1 to 0.2 percent of methylparaben, 0.1 to 0.5 percent of hydroxyethyl acrylate/sodium acryloyldimethyl sulfonate copolymer, the balance of water; wherein the yeast complex peptide composition comprises 0.5% -10% of a split yeast fermentation product lysate, 0.5% -2% of acetyl hexapeptide-8, 0.5% -1.5% of palmitoyl pentapeptide-4, and 0.5% -1.5% of a snake venom-like tripeptide.
2. The yeast essence with the effects of tightening and resisting wrinkles as claimed in claim 1, is characterized by being prepared from the following raw materials in percentage by mass:
2 to 14 percent of yeast composite peptide composition, 5 to 8 percent of rose water, 1 to 5 percent of glycerin, 0.5 to 1 percent of trehalose, 0.5 to 0.8 percent of carboxymethyl chitosan, 0.02 to 0.1 percent of low molecular sodium hyaluronate, 1 to 2.5 percent of hydrolyzed collagen, 1 to 5 percent of hydrolyzed oat protein, 0.8 to 1 percent of hydrolyzed yeast protein, 0.1 to 0.8 percent of glycerol stearate, 0.3 to 9 percent of dendrobium officinale extract, 3 to 8 percent of tremella extract, 1 to 2.5 percent of Adianthus tinus seed extract, 0.3 to 0.5 percent of camellia seed oil, 0.06 to 0.1 percent of tocopherol, 0.2 to 0.8 percent of Adianthus tinus seed oil, 0.1 to 0.5 percent of octyl glycol, 0.1 to 0.5 percent of ethanol, 0.1 to 0.2 percent of phenoxy methyl hydroxybenzoate, 0.1 to 0.3 percent of hydroxyethyl acrylate/dimethyl acryloyl copolymer, the balance of water; wherein the yeast complex peptide composition comprises 0.5% -9% of a split yeast fermentation product lysate, 0.5% -1.5% of acetyl hexapeptide-8, 0.5% -1.5% of palmitoyl pentapeptide-4, and 0.5% -2% of a snake venom-like tripeptide.
3. The yeast essence with the effects of tightening and resisting wrinkles as claimed in claim 1, is characterized by being prepared from the following raw materials in percentage by mass:
5 to 14 percent of yeast composite peptide composition, 6 to 8 percent of rose water, 2 to 5 percent of glycerin, 0.5 to 0.8 percent of trehalose, 0.6 to 0.8 percent of carboxymethyl chitosan, 0.03 to 0.1 percent of low molecular sodium hyaluronate, 1.5 to 2.5 percent of hydrolyzed collagen, 1.5 to 5 percent of hydrolyzed oat protein, 0.8 to 1 percent of hydrolyzed yeast protein, 0.2 to 0.8 percent of glycerol stearate, 0.5 to 9 percent of dendrobium officinale extract, 4 to 8 percent of tremella extract, 1.5 to 2.5 percent of Adiantum extract, 0.4 to 0.5 percent of camellia seed oil, 0.08 to 0.1 percent of tocopherol, 0.3 to 0.8 percent of Adiantum seed oil, 0.1 to 0.5 percent of octyl glycol, 0.1 to 0.5 percent of phenoxy ethanol, 0.1 to 0.2 percent of methylparaben, 0.1 to 0.3 percent of acrylic acid hydroxyethyl acrylate/dimethyl bovine acrylic acid sodium sulfonate, the balance of water; wherein the yeast complex peptide composition comprises 1.5% -8% of a split yeast fermentation product lysate, 1.5% -2% of acetyl hexapeptide-8, 1.5% -2% of palmitoyl pentapeptide-4 and 0.5% -2% of a snake venom-like tripeptide.
4. The yeast essence with the effects of tightening and resisting wrinkles as claimed in claim 1, is characterized by being prepared from the following raw materials in percentage by mass:
14% of yeast composite peptide composition, 8% of rose water, 5% of glycerol, 0.8% of trehalose, 0.8% of carboxymethyl chitosan, 0.1% of low-molecular sodium hyaluronate, 2.5% of hydrolyzed collagen, 5% of hydrolyzed oat protein, 1% of hydrolyzed yeast protein, 0.5% of glycerol stearate, 9% of dendrobium officinale extract, 8% of tremella extract, 2.5% of monkey-tree seed extract, 0.5% of camellia seed oil, 0.1% of tocopherol, 0.8% of monkey-tree seed oil, 0.5% of octyl glycol, 0.5% of phenoxyethanol, 0.2% of methylparaben, 0.3% of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and the balance of water; wherein the yeast complex peptide composition comprises 9% split yeast fermentation product lysate, 1.5% acetyl hexapeptide-8, 1.5% palmitoyl pentapeptide-4, and 2% snake venom-like tripeptide.
5. The method for preparing the yeast essence with the effects of tightening and resisting wrinkles as claimed in any one of claims 1 to 4 is characterized by comprising the following steps:
respectively heating the component A and the component B to 75-85 ℃ for dissolving and dispersing; then adding the component B into the component A, stirring, homogenizing and dispersing completely, cooling to 45-55 ℃, sequentially adding the component C, the component D and the component E, and stirring uniformly; finally, cooling to below 38 ℃ and discharging; wherein the content of the first and second substances,
the component A comprises: glycerol, methylparaben, trehalose, carboxymethyl chitosan, sodium hyaluronate and water;
and B component: hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, glyceryl stearate, camellia seed oil, tocopherol and Adiantum henryi seed oil;
and C, component C: a yeast complex peptide composition;
and (D) component: tremella extract and water, hydrolyzed collagen, hydrolyzed oat protein, hydrolyzed yeast protein, dendrobium officinale extract, schizosaccharomyces cerevisiae fermentation product lysate, rose water and Adiantum semen extract;
and E, component (E): phenoxyethanol and caprylyl glycol;
wherein the water of the component A accounts for 80-98% of the total mass of the water.
6. Use of the yeast essence with firming and anti-wrinkle effects according to any one of claims 1 to 4 for preparing cosmetics with firming and anti-wrinkle effects.
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