CN109846798B - Composition for tightening skin and cosmetic containing same - Google Patents
Composition for tightening skin and cosmetic containing same Download PDFInfo
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- CN109846798B CN109846798B CN201910330495.7A CN201910330495A CN109846798B CN 109846798 B CN109846798 B CN 109846798B CN 201910330495 A CN201910330495 A CN 201910330495A CN 109846798 B CN109846798 B CN 109846798B
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Abstract
The invention discloses a skin-tightening composition and a cosmetic comprising the same, wherein the skin-tightening composition comprises the following components in parts by weight: 2-9 parts of laminaria saccharina extract, 1-6 parts of plum fruit extract, 0.5-4 parts of quinpato bamboo extract, 2-7 parts of butterflybush flower extract and 3-7 parts of centella asiatica extract, and the components of the composition are synergistic, so that the effects of firming skin and resisting oxidation can be better exerted, and when the composition is applied to cosmetics, the effects of resisting wrinkles, resisting aging and enhancing skin elasticity can be well achieved; belongs to the technical field of cosmetics.
Description
Technical Field
The invention discloses a composition, in particular to a composition for tightening skin and a cosmetic containing the composition, and belongs to the technical field of cosmetics.
Background
There are two proteins in the dermis layer of skin: collagen and elastin, which support the skin and make it plump and tight, but these two proteins decrease naturally with the aging process of the human body, so that the skin loses elasticity, becomes loose and has no luster. Especially, fibroblasts are the most important cellular components in the dermis of the skin, and can synthesize and secrete fibers and extracellular matrix, and repair tissue wounds. With age, skin aging problems manifest, such as: dry, rough skin, increased wrinkles, loose skin, etc. are associated with decreased fibroblast numbers, decreased or abnormal synthesis function.
In addition to natural aging, skin is an external organ of the human body, is in direct contact with the environment, is more vulnerable to external damage and irritation such as ultraviolet rays and atmospheric pollution, and further aggravates aging phenomena such as skin dryness, wrinkles, sagging, and the like. Such as: long-term ultraviolet irradiation can form a large amount of free radicals in the skin, and the free radicals can oxidize the skin and damage collagen, so that the skin is aged, relaxed and loses elasticity. Furthermore, dry skin can cause cells to lose water and become depressed, lose activity and cause skin laxity. Facial skin laxity is a common manifestation of skin aging and has now become a hotspot in the study of skin cosmetology.
For the research of firming skin and resisting skin aging, Chinese patent CN102406581A discloses a firming skin care composition which is formed by combining fresh milk, olive oil, hamamelis extract, hydrolyzed soybean protein and ARTEMIA (ARTEMIA) extract, and can increase skin elasticity, improve skin wrinkles, improve skin moistening strength, and achieve the effects of firming skin and slowing down skin aging. Chinese patent CN109044941A discloses a skin-tightening, nourishing and moisturizing composition which comprises traditional Chinese medicine essence components, anti-allergy components, antioxidant components, hydrolyzed collagen, hydrolyzed silk and other components, and achieves the effects of improving skin texture and tightening skin by increasing the water content of the horny layer of aged skin and increasing the content of collagen. Chinese patent CN107822980A discloses a skin-tightening composition which comprises components such as an antioxidant, a humectant, an elastase inhibitor and the like, and has the effects of reducing skin oxidative damage, forming a water-locking barrier on the surface of skin and increasing the content of collagen so as to achieve the effect of delaying skin aging.
The cosmetics mainly have the following six anti-aging approaches: eliminating excessive free radicals, protecting against ultraviolet rays, promoting skin cell proliferation, supplementing collagen and elastin, moisturizing and repairing skin barrier, and strengthening skin defense and immune system. However, at present, some cosmetics for resisting skin aging have single anti-aging action ways or have poor anti-aging effect in the market. Therefore, there is a need to develop a cosmetic that is effective in firming skin and anti-aging.
Disclosure of Invention
In view of the above disadvantages, the present invention aims to provide a skin-tightening composition, which has synergistic effects of the components, can effectively promote the synthesis of collagen, accelerate the proliferation of fibroblasts, and simultaneously has excellent moisturizing and antioxidant effects, and when the composition is applied to cosmetics, the skin-tightening composition can provide the cosmetics with good effects of tightening skin, resisting wrinkles, resisting aging, and enhancing skin elasticity.
Therefore, the first technical scheme provided by the application is as follows:
the composition for tightening the skin comprises the following components in parts by weight: 2-9 parts of laminaria saccharina extract, 1-6 parts of plum fruit extract, 0.5-4 parts of quinpatel mangosteen extract, 2-7 parts of butterflybush flower extract and 3-7 parts of centella asiatica extract.
Further, the composition also comprises 1-5 parts of pansy extract.
Further, the composition also comprises 3-6 parts of pomegranate bark extract.
Preferably, the composition comprises the following components in parts by weight: 3-7 parts of laminaria saccharina extract, 2-5 parts of plum fruit extract, 1-3 parts of quinpatel mangosteen extract, 3-6 parts of butterflybush flower extract and 4-6 parts of centella asiatica extract.
More preferably, the composition comprises the following components in parts by weight: 5-6 parts of laminaria saccharina extract, 3-4 parts of plum fruit extract, 2-3 parts of quinpatel mangosteen extract, 4-5 parts of butterflybush flower extract, 4-5 parts of centella asiatica extract and 2-4 parts of pansy extract.
More preferably, the composition comprises the following components in parts by weight: 5-6 parts of kelp extract, 3-4 parts of plum fruit extract, 2-3 parts of quinpatel mangosteen extract, 4-5 parts of butterflybush flower extract, 4-5 parts of centella asiatica extract, 2-3 parts of pansy extract and 4-5 parts of pomegranate bark extract.
More preferably, in the skin-tightening composition, the preparation method of the buddleja officinalis extract is as follows:
1) drying flos Buddlejae, pulverizing, and sieving with 40-70 mesh sieve to obtain flos Buddlejae powder;
2) placing the buddleja officinalis powder in a subcritical extraction kettle, pumping an extracting agent into an extraction system when all parts of the system reach a set temperature of 110-;
3) loading the concentrated solution obtained in the step 2) on an AB-8 macroporous adsorption resin column, eluting with water until the eluate shows negative in alpha-naphthol test, discarding the eluate, eluting with 50-70% ethanol water solution, recovering the eluate, and concentrating under reduced pressure to dry to obtain flos Buddlejae extract.
Further, in the skin firming composition, the extractant is ultrapure water.
The second technical scheme provided by the invention is as follows:
a cosmetic containing the above mentioned ingredients for tightening skin is water, lotion, essence, cream, jelly, facial mask, etc. During production, the selection and preparation processes of other components in the cosmetic can be carried out according to conventional operations in the field, and the composition for tightening the skin accounts for 0.8-5.6% of the total mass of the cosmetic.
Compared with the prior art, the invention has the following beneficial effects:
(1) according to the technical scheme provided by the invention, the laminaria saccharina extract and the plum extract can enhance the synthesis of collagen, and have a certain inhibition effect on the activity of elastase; the flos Buddlejae extract can effectively scavenge active oxygen and free radical generated under ultraviolet, blue light and infrared radiation, protect skin from oxidation damage, and maintain skin redox balance; the extract of Sasa quinata has effects in reducing free radical generation, and resisting oxidation; in addition, the polyuronide rich in the laminaria saccharina can form a membrane with excellent moisturizing effect with protein in the skin, and the barrier function of the stratum corneum is improved by increasing the moisture of the stratum corneum to further resist external damage, so that the effect of delaying skin relaxation and sagging is achieved. The centella extract is rich in asiaticoside, can directly act on human fibroblasts, reform a dermis structure, improve the density and compactness of skin, reduce the roughness of the skin, and has strong promotion effect on the synthesis of collagen and elastin; repairing elastic fiber and collagen fiber, improving elasticity of relaxed skin, increasing skin smoothness, and resisting wrinkle, and asiaticoside can promote fibroblast proliferation, and has great effects on skin recombination and repair. The active components are compounded, so that the collagen generation, the fibroblast proliferation and the antioxidation effect are enhanced.
(2) According to the technical scheme provided by the invention, the pansy extract is rich in oligosaccharide, has the effect of regulating the hydration of the epidermis, can obviously improve the synthesis of aquaporin-3 to promote the migration of water from the dermis to the epidermis and promote the bonding of the intercellular spaces of the pansy, so that the capacity of retaining water is improved by improving the content of a membrane receptor CD44, and the pansy extract can play a role in deep moisturizing in cooperation with other components to further enhance the repair function of a skin barrier.
(3) According to the technical scheme provided by the invention, the pomegranate bark extract has good lipid peroxidation resistance, can be scientifically combined with other components, can improve the oxidation resistance, and simultaneously has the enhancement effects on the synthesis of collagen, water replenishing, moisture retention and cell proliferation due to the synergistic effect of the components, so that the effects of tightening skin, reducing wrinkles, increasing elasticity and delaying senescence are achieved.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. For process parameters or conditions not specifically mentioned, it can be carried out with reference to conventional techniques.
The raw materials used in the present invention are all purchased from commercial sources. Wherein the Laminaria Saccharina extract is purchased from Guangzhou Baihabo Co., Ltd, the Prunus mume extract is purchased from Guangzhou Kodo chemical Co., Ltd, the Kualpa stolonifera extract is purchased from Guangzhou Polyoceanization technology Co., Ltd, the Centella extract is purchased from vast Sendzein Co., Ltd, the Viola tricolor extract is purchased from Guangzhou Australia trade Co., Ltd, and the pomegranate rind extract is purchased from Guangzhou Ruyu chemical technology Co., Ltd.
Example 1
The invention provides a skin-firming composition which comprises the following components in parts by weight: 2g of laminaria saccharina extract, 1g of plum fruit extract, 0.5g of quintet pink bamboo extract, 2g of buddleja officinalis extract and 3g of centella asiatica extract.
Example 2
The invention provides another skin firming composition which comprises the following components in parts by weight: 3g of laminaria saccharina extract, 2g of plum fruit extract, 1g of quilpate dendrocalamus extract, 3g of butterflybush flower extract and 4g of centella asiatica extract.
Example 3
The invention provides another skin firming composition which comprises the following components in parts by weight: 7g of laminaria saccharina extract, 5g of plum fruit extract, 3g of quinapride sasa extract, 6g of butterflybush flower extract and 6g of centella asiatica extract.
Example 4
The invention provides another skin firming composition which comprises the following components in parts by weight: 9g of laminaria saccharina extract, 6g of plum fruit extract, 4g of quinalpa bambusae extract, 7g of buddleja officinalis extract and 7g of centella asiatica extract.
Example 5
The invention provides another skin firming composition which comprises the following components in parts by weight: 2g of laminaria saccharina extract, 1g of plum fruit extract, 0.5g of quintet pink bamboo extract, 2g of butterflybush flower extract, 3g of centella asiatica extract and 1g of pansy extract.
Example 6
The invention provides another skin firming composition which comprises the following components in parts by weight: 5g of laminaria saccharina extract, 3g of plum fruit extract, 2g of quinalpa bambusae extract, 4g of butterflybush flower extract, 4g of centella asiatica extract and 2g of pansy extract.
Example 7
The invention provides another skin firming composition which comprises the following components in parts by weight: 6g of laminaria saccharina extract, 4g of plum fruit extract, 3g of quinalpa bambusae extract, 5g of butterflybush flower extract, 5g of centella asiatica extract and 4g of pansy extract.
Example 8
The invention provides another skin firming composition which comprises the following components in parts by weight: the composition comprises 9g of laminaria saccharina extract, 6g of plum fruit extract, 4g of quinalpa bambusae extract, 7g of butterflybush flower extract, 7g of centella asiatica extract and 5g of pansy extract.
Example 9
The invention provides another skin firming composition which comprises the following components in parts by weight: 2g of laminaria saccharina extract, 1g of plum fruit extract, 0.5g of quinalpa bambusae extract, 2g of buddleja officinalis extract, 3g of centella asiatica extract and 3g of pomegranate rind extract.
Example 10
The invention provides another skin firming composition which comprises the following components in parts by weight: 5g of laminaria saccharina extract, 4g of plum fruit extract, 2g of quinalpa bambusae extract, 4g of butterflybush flower extract, 5g of centella asiatica extract and 5g of pomegranate rind extract.
Example 11
The invention provides another skin firming composition which comprises the following components in parts by weight: 9g of laminaria saccharina extract, 6g of plum fruit extract, 4g of quinalpa bambusae extract, 7g of butterflybush flower extract, 7g of centella asiatica extract and 6g of pomegranate rind extract.
Example 12
The invention provides another skin firming composition which comprises the following components in parts by weight: 2g of laminaria saccharina extract, 1g of plum fruit extract, 0.5g of quinalpa bambusae extract, 2g of butterflybush flower extract, 3g of centella asiatica extract, 1g of pansy extract and 3g of pomegranate peel extract.
Example 13
The invention provides another skin firming composition which comprises the following components in parts by weight: 5g of laminaria saccharina extract, 3g of plum fruit extract, 2g of quinalpa bambusae extract, 4g of butterflybush flower extract, 4g of centella asiatica extract, 2g of pansy extract and 4g of pomegranate peel extract.
Example 14
The invention provides another skin firming composition which comprises the following components in parts by weight: 6g of laminaria saccharina extract, 4g of plum fruit extract, 3g of quinalpa bambusae extract, 5g of butterflybush flower extract, 5g of centella asiatica extract, 3g of pansy extract and 5g of pomegranate peel extract.
Example 15
The invention provides another skin firming composition which comprises the following components in parts by weight: the composition comprises 9g of laminaria saccharina extract, 6g of plum fruit extract, 4g of quinalpa bambusae extract, 7g of butterflybush flower extract, 7g of centella asiatica extract, 5g of pansy extract and 6g of pomegranate peel extract.
The preparation method of the buddleja officinalis extract in the embodiment mainly comprises the following steps:
1) drying flos Buddlejae, pulverizing, and sieving with 40-70 mesh sieve (preferably 60 mesh sieve) to obtain flos Buddlejae powder;
2) placing the buddleja officinalis powder in a subcritical water extraction kettle, pumping an extractant (ultrapure water) into the extraction system when all parts of the system reach a set temperature of 110-;
3) loading the concentrated solution obtained in step 2) onto AB-8 macroporous adsorbent resin column, eluting with water until the eluate shows negative in alpha-naphthol test, discarding the eluate, eluting with 50-70% ethanol (preferably 60% ethanol) water solution, recovering the eluate, and concentrating under reduced pressure to dry to obtain flos Buddlejae extract.
To demonstrate the effect of the present invention, comparative experimental examples of the present application are given below:
comparative example 1
A composition comprising the following components in parts by weight: 11g of laminaria saccharina extract, 7g of plum fruit extract and 4g of quinpalett pink extract.
Comparative example 2
A composition comprising the following components in parts by weight: the feed additive comprises 11g of laminaria saccharina extract, 5g of butterflybush flower extract and 3g of centella asiatica extract.
Comparative example 3
A composition comprising the following components in parts by weight: 7g of plum extract, 4g of quinalpa bambusoides extract, 6g of pansy extract and 5g of pomegranate bark extract.
Comparative example 4
A composition comprising the following components in parts by weight: 7g of plum extract, 5g of butterflybush flower extract, 3g of centella asiatica extract, 6g of pansy extract and 5g of pomegranate bark extract.
The preparation method of the extract of Buddleja officinalis in the comparative example was the same as that in the example.
The preparation method of the composition comprises the following steps: weighing each component according to any one group of weight in examples 1-15 and comparative examples 1-4, and stirring and mixing uniformly at normal temperature to obtain the nano-particles.
In order to better illustrate the advantages of the present invention, the experimental results of the technical solution provided by the present invention are given below:
test 1: effect on collagen Synthesis
1) Test samples: the compositions of examples 1 to 15 and comparative examples 1 to 4 were mixed and diluted with ultrapure water to give a test solution having a mass fraction of 2%.
2) The test method comprises the following steps: the content of collagen I in fibroblasts is determined by an enzyme-linked immunosorbent assay, the fibroblasts are digested by trypsin and transferred into a 96-well culture plate, the marginal wells are filled with sterile PBS (phosphate buffer solution), the culture plate is moved into an incubator to be continuously cultured, when the cells are completely attached to the wall and grow, 30 mu L/well of sample solutions of examples and comparative examples are sequentially added by using a microsyringe, PBS (0.01M) with the same volume is added into a control group, the content of the collagen I is determined according to the instruction of a kit after the samples are added for 48h, 5 wells are added into each group, and the collagen synthesis amount of the control group is 100 percent by using the samples without the examples and the comparative examples. The test results are shown in table 1.
TABLE 1 Effect on collagen Synthesis
As can be seen from the experimental results of Table 1, the collagen type I content was significantly increased when the cells were treated with the compositions of examples 1-15, as compared to the control group not containing the composition of the present invention. The compositions of comparative examples 1 to 4, on the other hand, showed a smaller increase in collagen type I, indicating that the synergistic effect of the compositions of the present invention is better at promoting collagen production.
And (3) testing 2: proliferation of fibroblast cells
1) Test samples: the compositions of examples 1 to 15 and comparative examples 1 to 4 were mixed and diluted with ultrapure water to give a test solution having a mass fraction of 2%.
2) The test method comprises the following steps: the prepared fibroblast suspension is mixed at 2X 104Each cell/mL was inoculated in a 96-well plate at a concentration of 100. mu.L per well, and after the cells were attached to the wall, 20. mu.L of the above-mentioned test solution was added to each well by a microsyringe, and the same volume of PBS (0.01M) was added to the control group, and the cells were transferred to an incubator (37 ℃ C., 5% carbon dioxide, saturated humidity) and cultured for 24 hours, and then 20. mu.L of 1mg/mL MTT solution was added and cultured for 4 hours under the same conditions. The culture medium in each well was carefully aspirated, 100. mu.L of DMSO was added to each well, the wells were placed on a shaker and shaken at a low speed for 10min to dissolve the crystals sufficiently, the absorbance A of each well was measured at OD490nm of an enzyme-linked immunosorbent assay, and at the same time, wells (medium, MTT, DMSO) were set to zero, and the cell viability, which was 100% (test sample A/control A) x 100%, was calculated according to the following formula, using the control group without the addition of the active ingredient. The test results are shown in table 2.
TABLE 2 proliferation of fibroblasts
| Sample (I) | Proportion (%) relative to control group |
| Control group | 100 |
| Example 1 | 123.78 |
| Example 2 | 124.23 |
| Example 3 | 124.46 |
| Example 4 | 125.70 |
| Example 5 | 127.52 |
| Example 6 | 128.03 |
| Example 7 | 128.75 |
| Example 8 | 129.47 |
| Example 9 | 130.21 |
| Example 10 | 130.94 |
| Example 11 | 131.16 |
| Example 12 | 133.79 |
| Example 13 | 134.12 |
| Example 14 | 134.57 |
| Example 15 | 135.48 |
| Comparative example 1 | 107.52 |
| Comparative example 2 | 108.05 |
| Comparative example 3 | 108.23 |
| Comparative example 4 | 109.44 |
From the experimental results in table 2, it can be seen that, compared with the control group without the composition of the present invention, the compositions of the examples have significant promoting effect on the proliferation of skin fibroblasts, the survival rate of the cells of the examples 12-15 is as high as more than 133%, while the comparative compositions have small proliferation effect on the fibroblasts, which indicates that the scientific compounding of the components of the present invention can significantly increase the number of the fibroblasts, and improve the symptoms of dry, rough and increased wrinkles of the skin.
And (3) testing: antioxidation effect
This experiment evaluates the antioxidant properties of the compositions of the present invention by determining their ability to scavenge hydroxyl radicals and DPPH radicals.
1) Test samples: the compositions of examples 1 to 15 and comparative examples 1 to 4 were mixed and diluted with ultrapure water to give a test solution having a mass fraction of 2%.
2) The test method comprises the following steps:
hydroxyl radical scavenging experiments: taking 0.5mL of 0.75mmol/L O-diazaphenanthrene absolute ethyl alcohol solution, respectively adding 2mL and 1mL of 0.2mol/L pH 7.4 phosphate buffer solution into a test tube with a plug, fully mixing, adding 0.5mL of 0.75mmol/L FeSO 4.7H 2O solution, mixing again, adding 0.5mL of 0.01% (v/v) H2O2, measuring each mixed solution at 536nm after 60min in 37 ℃ constant temperature water bathThe absorbance value of the solution is recorded As, and the absorbance value is measured by using distilled water As a blank instead of the sample solution and recorded As AbReplacing H with distilled water2O2And measuring the absorbance value An of the damage group, and calculating the hydroxyl radical clearance of the test sample according to the following formula: hydroxyl radical scavenging rate (%) [ (As-An)/(A)b-An)]X 100%, the average of three measurements was taken. The test results are shown in table 3.
DPPH free radical scavenging experiments: taking 3mL of DPPH-absolute ethanol solution with the concentration of 0.2mmol/L into a cuvette, adding 1mL of test sample, mixing uniformly, keeping out of the sun for 30min at room temperature, measuring the absorbance at the wavelength of 517nm, and recording the absorbance as A1And the absorbance values of the solution added with 3mL of absolute ethanol and 1mL of the test sample solution are recorded as A2And the light absorption value of the solution added with 3mL of anhydrous alcohol solution and 1mL of anhydrous alcohol solution is recorded as A3. DPPH radical clearance was calculated as follows: DPPH radical scavenging ratio (%) - [1- (A)1-A2)/A3]X 100%, the average of three measurements was taken. The test results are shown in table 3.
TABLE 3 results of the antioxidation test
As can be seen from the experimental results in Table 3, the compositions of the examples of the present invention have strong scavenging ability for hydroxyl radicals and DPPH radicals, the scavenging ability for the examples 12-15 is as high as 80%, and the scavenging ability for the comparative example composition is only about 30%, which shows that the composition of the present invention can effectively scavenge free radicals, protect skin from oxidative damage, and have antioxidant and anti-aging effects.
The compositions provided in examples 1-15 and comparative examples 1-4 were directly added to a conventional cosmetic cream base and stirred uniformly, the composition accounting for 2% of the total mass of the cosmetic cream. The prepared cosmetics were subjected to a performance test.
And (4) testing: testing of moisturizing function
1) Test samples: the compositions of examples 2, 4, 6, 8, 10, 12, 14, comparative examples 2, 4 were used as control creams and cream bases without the composition.
2) The test method comprises the following steps: 100 volunteers of 20-45 years old are selected as trial objects, the 100 volunteers are randomly divided into 10 groups, 10 volunteers are in each group, and the skin of the test subject is healthy and meets the selection standard. 3 days before detection, the face does not use any cosmetics, each group of subjects respectively takes a proper amount of cream to apply on the skin of the face, the cream is respectively used once in the morning and at the evening every day for 30 days continuously, the moisture content of the skin is detected by a skin moisture content tester CM825 on the 0 th day and the 30 th day, the detection is respectively repeated for 5 times to obtain an average value, and the moisture content condition of the skin before and after the cream is used is evaluated. The test results are shown in table 4.
TABLE 4 moisturizing functional test
| Sample (I) | Water content at day 0 | Moisture content on day 30 | Moisture content increase rate (%) |
| Example 2 cream | 32.16 | 40.66 | 26.43％ |
| Example 4 cream | 30.54 | 38.51 | 26.10％ |
| Example 6 cream | 29.78 | 37.79 | 26.90％ |
| Example 8 cream | 32.63 | 41.56 | 27.37％ |
| Example 10 cream | 31.49 | 40.06 | 27.21％ |
| Example 12 cream | 31.92 | 40.90 | 28.13％ |
| Example 14 cream | 29.40 | 37.77 | 28.47％ |
| Comparative example 2 cream | 30.81 | 34.16 | 10.87％ |
| Comparative example 4 cream | 31.19 | 35.07 | 12.44％ |
| Control cream base | 32.05 | 33.12 | 3.34％ |
The experimental results in table 4 show that the cream prepared by using the composition of the embodiment of the invention can significantly improve the moisture content of the skin, the moisture content increase rate of the skin of the cream of the embodiments 12 and 14 can reach 28% after the cream is continuously used for 30 days, and the moisture content increase of the cream of the comparative example is not obvious, which shows that the composition of the invention has good moisturizing effect after being compounded with various components, can provide sufficient moisture for skin cells, and enables the skin to be more moist.
And (5) testing: skin elasticity test
1) Test samples: the compositions of examples 1, 3, 5, 7, 9, 11, 13, 15, comparative examples 1, 3 were used as control to prepare creams and cream bases without the composition.
2) The test method comprises the following steps: 110 volunteers with wrinkles and no damage to healthy skin of 30-45 years old were selected, randomly divided into 11 groups of 10 individuals, and the test samples were used. The subject applies a proper amount of face cream on the face, and the face cream is applied once every morning and evening for 30 days continuously. During the experiment, the subject was not able to apply any other cosmetic product at the experimental site.
Data acquisition is carried out by using a skin elasticity meter MPA580 respectively at the time of nonuse and the time of 30 days, the test part is a cheekbone part, a probe repeatedly measures for 3 times in the same measured area during measurement, and an average value is obtained. The test parameter is R2 (the ratio of the springback amount Ua of the skin without negative pressure to the maximum stretch amount Uf with negative pressure), the closer R2 is to 1, the better the elasticity of the skin, the average change value of R2 is the 4 th cycle R2 value to the 0 th cycle R2 value, and the average change rate of R2 is the average change value of R2/the 0 th cycle R2 value. The test results are shown in table 5.
Table 5 skin elasticity test results
The experimental results in table 5 show that the cream prepared by using the composition of the embodiment can effectively improve the skin elasticity after 30 days, and the comparison effect is obvious, which shows that the composition of the invention can better improve skin wrinkles, delay skin aging and achieve the effect of tightening skin by synergy.
In conclusion, the natural active substances of the laminaria saccharina extract, the plum fruit extract, the quintet bamboo extract, the butterflybush flower extract, the centella asiatica extract, the pansy extract and the pomegranate bark extract are scientifically combined, and the synergistic effect has the promotion effects on the synthesis of collagen, the water replenishing and moisture preserving, the fibroblast proliferation and the antioxidation, so that the effects of skin tightening and aging resistance are achieved.
The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.
Claims (8)
1. The composition for tightening the skin is characterized by comprising the following components in parts by weight: 2-9 parts of laminaria saccharina extract, 1-6 parts of plum fruit extract, 0.5-4 parts of quinpatel mangosteen extract, 2-7 parts of buddleja officinalis extract and 3-7 parts of centella asiatica extract;
the preparation method of the buddleja officinalis extract comprises the following steps:
1) drying flos Buddlejae, pulverizing, and sieving with 40-70 mesh sieve to obtain flos Buddlejae powder;
2) placing the buddleja officinalis powder in a subcritical extraction kettle, pumping extractant ultrapure water into the extraction system when all parts of the system reach the set temperature of 110-;
3) loading the concentrated solution obtained in the step 2) on an AB-8 macroporous adsorption resin column, eluting with water until the eluate shows negative in alpha-naphthol test, discarding the eluate, eluting with 50-70% ethanol water solution, recovering the eluate, and concentrating under reduced pressure to dry to obtain flos Buddlejae extract.
2. The composition for tightening skin according to claim 1, further comprising pansy extract 1-5 parts.
3. The composition for tightening skin according to claim 1 or 2, wherein the composition further comprises 3 to 6 parts of pomegranate rind extract.
4. The composition for tightening skin according to claim 1, wherein the composition comprises the following components in parts by weight: 3-7 parts of laminaria saccharina extract, 2-5 parts of plum fruit extract, 1-3 parts of quinpatel mangosteen extract, 3-6 parts of butterflybush flower extract and 4-6 parts of centella asiatica extract.
5. The composition for tightening skin according to claim 2, wherein the composition comprises the following components in parts by weight: 5-6 parts of laminaria saccharina extract, 3-4 parts of plum fruit extract, 2-3 parts of quinpatel mangosteen extract, 4-5 parts of butterflybush flower extract, 4-5 parts of centella asiatica extract and 2-4 parts of pansy extract.
6. The skin tightening composition as set forth in claim 3, wherein the composition comprises the following components in parts by weight: 5-6 parts of kelp extract, 3-4 parts of plum fruit extract, 2-3 parts of quinpatel mangosteen extract, 4-5 parts of butterflybush flower extract, 4-5 parts of centella asiatica extract, 2-3 parts of pansy extract and 4-5 parts of pomegranate bark extract.
7. A cosmetic comprising the skin-firming composition according to claim 1, wherein the skin-firming composition is 0.8 to 5.6% by mass of the total mass of the cosmetic.
8. The cosmetic according to claim 7, wherein the cosmetic is one of water, lotion, essence, cream, gel, and pack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910330495.7A CN109846798B (en) | 2019-04-23 | 2019-04-23 | Composition for tightening skin and cosmetic containing same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910330495.7A CN109846798B (en) | 2019-04-23 | 2019-04-23 | Composition for tightening skin and cosmetic containing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109846798A CN109846798A (en) | 2019-06-07 |
| CN109846798B true CN109846798B (en) | 2021-08-13 |
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| CN107875067A (en) * | 2017-12-19 | 2018-04-06 | 湖南御家化妆品制造有限公司 | Skin care composition and use thereof |
| CN108014045A (en) * | 2017-12-25 | 2018-05-11 | 广东芭薇生物科技股份有限公司 | A kind of man's skin care compositions and its application |
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| CN107875067A (en) * | 2017-12-19 | 2018-04-06 | 湖南御家化妆品制造有限公司 | Skin care composition and use thereof |
| CN108014045A (en) * | 2017-12-25 | 2018-05-11 | 广东芭薇生物科技股份有限公司 | A kind of man's skin care compositions and its application |
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