CN105125476A - Anti-wrinkle essence and preparing method thereof - Google Patents
Anti-wrinkle essence and preparing method thereof Download PDFInfo
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- CN105125476A CN105125476A CN201510673049.8A CN201510673049A CN105125476A CN 105125476 A CN105125476 A CN 105125476A CN 201510673049 A CN201510673049 A CN 201510673049A CN 105125476 A CN105125476 A CN 105125476A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
- A61K8/986—Milk; Derivatives thereof, e.g. butter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The invention belongs to the technical field of cosmetics and particularly relates to anti-wrinkle essence and a preparing method thereof. The anti-wrinkle essence is prepared from cyclomethicone, butanediol, polydimethylsiloxane, poly(sodium L-glutamate), glycerinum, propylene glycol, polyglycerol-10, dipropylene glycol, erythritol, hydroxyethyl acrylate/acryloyl 2 methyl taurine sodium copolymer, bio-saccharide gum, xylitol, C20-22 alcohol phosphate/C20-22 alcohol, lactic acid bacillus/ pomegranate fruit extracts of fermented products, arctic rock chlamydomonas essence, starfish essence, hexapeptide-3, orange flower essence, gentian root extracts, arbutin, milk protein, tranexamic acid and the like. The anti-wrinkle essence is good in permeability and easy to absorb, effective moisturizing is achieved, skin wrinkles are repaired and inhibited from being regenerated, and skin aging is delayed.
Description
Technical field
The present invention relates to cosmetic technical field, be specifically related to a kind of anti-wrinkle essence and preparation method thereof.
Background technology
Adolescence is people's the prettiest beautiful period in life, now skin slip, gloss, plentiful, high resilience, white touched with red.After 25 years old, metabolism starts to slow down, and moisture and subcutaneous fat reduce, and elastic fiber is thicker gradually, and skin crumple, gloss are disappeared.After 40 years old, hormone in vivo dysequilibrium, keratin reduces, elastic fibers break, and cutis laxa, coarse, wrinkle increase, and progress into aging period.Skin aging is the outstanding behaviours of whole body aging, wherein facial skin is aging particularly evident, in human body, fibroblastic quantity reduces gradually, the collagen protein of its secretion and elastic fibers albumen are also because oxidizedly to reduce gradually, rupture, just disappear to the supporting role of epidermis, cause inhomogenous subsiding, skin corium starts thinning, skin elasticity is deteriorated, and wrinkle also starts to produce gradually.
Skin aging, except affecting by the objective factor such as age, heredity, is also subject to the various factors such as daylight, environment, health.Undue Exposure to Sunlight or be exposed to the sun, not only accelerates skin aging, also easy chromogenesis speckle; Live in serious pollution environment for a long time or the chemical substance that too much contact is harmful to skin, all can make skin damage, accelerated ageing; Malnutrition, lassitude, to be eaten up with illness, the easier premature aging of skin.Particularly modern's life stress is large, overtime work is stayed up late, long-time to computer, smoking, do not have enough sleep, stay in air-conditioned room for a long time, drink, excess eye-using etc. becomes life normality.According to the U.S. beautiful scientific center research of Dior Christian Dior, every day, the each layer of skin can accumulate the cellular elements toxin in a large number caused by inherent or extrinsic factor, skin cell can be caused to suffocate, and have impact on the Dusuqing removing solid capacity of skin self, thus just create the worries such as the colour of skin is obscure, shortage gloss, tired state are showed fully; Increase the weight of the burden of skin, accelerate skin aging.
Although skin aging is irreversible physiological phenomenon, its process can delay or slow down.For face wrinkles, common wrinkle removal method is operation reduce wrinkle, injection wrinkle removal and anti-wrinkle cosmetic.The treatment cost of operation reduce wrinkle and injection wrinkle removal is high, have a big risk, and is not that each consumer can bear, and anti-wrinkle cosmetic is one and well selects.Anti-wrinkle cosmetic is divided into again anti-wrinkle face mask, facial milk cleanser, and crease-resistant cosmetic water, facial cream, essence etc. are multiple, and anti-wrinkle face mask, facial milk cleanser are short in the time of staying of face, DeGrain, need life-time service, and use procedure is also inconvenient; In crease-resistant cosmetic water, facial cream, the content of active component is relatively low, its anti-wrinkle effect is also not obvious, and the nutrient substance that essence contains and active component comparatively cosmetic water, facial cream want height more, its effect is powerful, anti-wrinkle effect is remarkable, but current essence is common exists the problems such as poor permeability, not easily absorption, and anti-wrinkle effect need to improve.
Therefore, be necessary research and development its good penetrability a kind of, easily absorb, effective replenishing water and preserving moisture, repair wrinkle of skin, suppress wrinkle regeneration, delay skin aging anti-wrinkle essence.
Summary of the invention
In order to overcome the deficiencies in the prior art, the object of the present invention is to provide a kind of anti-wrinkle essence, its good penetrability, easily absorbs, effective replenishing water and preserving moisture, repairs wrinkle of skin, suppresses wrinkle regeneration, delay skin aging.
To achieve these goals, technical scheme of the present invention is as follows:
A kind of anti-wrinkle essence, comprise the raw material of following weight percent meter: Cyclomethicone 4 ~ 10%, butanediol 4 ~ 10%, polydimethylsiloxane 2 ~ 8%, polyglutamic acid sodium 1 ~ 5%, glycerol 0.5 ~ 4%, propylene glycol 0.5 ~ 4%, Natrulon H-10 0.5 ~ 4%, dipropylene glycol 0.5 ~ 4%, erithritol 0.5 ~ 4%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 0.5 ~ 4%, biological carbohydrate gum-10.5 ~ 3%, xylitol 0.5 ~ 3%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.5 ~ 3%, lactobacillus/Punica granatum L. tunning extract 0.3 ~ 2%, arctic Ascophyllum nodosum elite 0.3 ~ 2%, Asterias amurensis Lutken elite 0.3 ~ 2%, six peptides-30.3 ~ 2%, orange blossom elite 0.3 ~ 2%, Gentiana lutea extract 0.3 ~ 2%, arbutin 0.1 ~ 1%, milk protein 0.1 ~ 1%, tranamic acid 0.05 ~ 1%, methyl hydroxybenzoate 0.01 ~ 0.1%, phenoxyethanol 0.01 ~ 0.1%, essence 0.0002 ~ 0.05% and water 40 ~ 70%.
Further, described anti-wrinkle essence comprises the raw material of following weight percent meter: Cyclomethicone 4 ~ 8%, butanediol 4 ~ 8%, polydimethylsiloxane 2 ~ 6%, polyglutamic acid sodium 1 ~ 4%, glycerol 0.5 ~ 3%, propylene glycol 0.5 ~ 3%, Natrulon H-10 0.5 ~ 3%, dipropylene glycol 0.5 ~ 2%, erithritol 0.5 ~ 2%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 0.5 ~ 2%, biological carbohydrate gum-10.5 ~ 1.5%, xylitol 0.5 ~ 1.5%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.5 ~ 1.5%, lactobacillus/Punica granatum L. tunning extract 0.3 ~ 1%, arctic Ascophyllum nodosum elite 0.3 ~ 1%, Asterias amurensis Lutken elite 0.3 ~ 1%, six peptides-30.3 ~ 1%, orange blossom elite 0.3 ~ 1%, Gentiana lutea extract 0.3 ~ 1%, arbutin 0.1 ~ 0.6%, milk protein 0.1 ~ 0.6%, tranamic acid 0.05 ~ 0.3%, methyl hydroxybenzoate 0.01 ~ 0.05%, phenoxyethanol 0.01 ~ 0.05%, essence 0.0002 ~ 0.01% and water 60 ~ 70%.
As the preferred embodiment of the present invention, described anti-wrinkle essence is made up of the raw material of following weight percent meter: Cyclomethicone 6%, butanediol 6%, polydimethylsiloxane 3%, polyglutamic acid sodium 2%, glycerol 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, erithritol 1%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 1%, biological carbohydrate gum-10.8%, xylitol 0.8%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.8%, lactobacillus/Punica granatum L. tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, Asterias amurensis Lutken elite 0.5%, six peptides-30.6%, orange blossom elite 0.5%, Gentiana lutea extract 0.5%, arbutin 0.2%, milk protein 0.2%, tranamic acid 0.1%, methyl hydroxybenzoate 0.01%, phenoxyethanol 0.01%, essence 0.0015% and water 68.8785%.
In technical solution of the present invention, described lactobacillus/Punica granatum L. tunning extract contains a large amount of ellagic acids, polyphenol and anthocyanidin, and its non-oxidizability is strong, can effectively in and free radical, enhance metabolism, reduce visible microgroove.
Described arctic Ascophyllum nodosum elite is rich in algin body, brown algae polyphenols, sodium alginate, algae carotene and ocean trace element, skin thickness can be increased, improve the mechanical performance of skin, improve barrier function, promote collagen protein and elastin laminin with become, suppress digestive enzyme, thus improve the texture of skin, color and luster and brightness.
Described Asterias amurensis Lutken elite can promote the metabolism of skin, increase epidermal barrier regeneration, more increase the synthesis of glycosaminoglycan (GAGS) and III, type Ⅳ collagen albumen simultaneously, help skin effectively to anti-wrinkle, make skin water tender flexible, and without any side effect and zest.
Described six peptides-3 have similarly can suppress neurotransmitter, conduction function between block nerves muscle, avoid muscle excess shrinkage, prevent microgroove from being formed, the strength delaying muscle contraction can also be subtracted, allow loosening all muscles, reduce the generation of dynamic stricture of vagina and elimination microgroove, effectively reorganize collagen elastic force, the activity of elastin can be increased, face's lines are loosened, and wrinkle smooths to improve and relaxes.
Described orange blossom elite is containing multiple whitening active ingredients, melanin established in skin can be derived layer by layer, and get rid of along with the metabolism of aging cutin, the turbidity of assembling in skin and the harmful substance produced because of pollution can also be got rid of the while that skin being pale gradually, strengthen cell viability, help cell regeneration, increase skin elasticity.
It is obscure that described Gentiana lutea extract can help to eliminate skin surface, simultaneously the formation of effective check melanin, desalination mottle, bright color, clean white muscle skin.
Described milk protein contains hydrophilic moisturizing ingredient can protect skin total moisture to prevent from running off; several amino acids composition can promote the quick reparation of injured skin; the content of albumen in skin can be enriched; the intensity of connective tissue can be strengthened simultaneously; can promote that skin generates albumen; prevent and reduce wrinkle, making skin plentiful and flexible.
Anti-wrinkle essence of the present invention contains lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, orange blossom elite, the various plants compositions such as Gentiana lutea extract, again in conjunction with Cyclomethicone of the present invention, butanediol, polydimethylsiloxane, polyglutamic acid sodium, glycerol, propylene glycol, the basic materials such as Natrulon H-10, each component is worked in coordination with, make anti-wrinkle essence good penetrability of the present invention, easy absorption, deep water supplement moisturizing, nourish maintenance skin, promote cell regeneration, repair wrinkle of skin, suppress wrinkle regeneration, delay skin aging, improve cutis laxa sagging, bright skin compacts, promote skin year slight.
Present invention also offers the preparation method of above-mentioned anti-wrinkle essence, specifically comprise the following steps:
S1, by Cyclomethicone, polydimethylsiloxane and C20-22 alcohol phosphate ester/C20-22 alcohol, add in oil phase pot, be heated to 80 ~ 85 DEG C, be stirred to and dissolve completely, obtain material A;
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerol, propylene glycol, Natrulon H-10, dipropylene glycol, erithritol, xylitol, arbutin and methyl hydroxybenzoate add in aqueous phase pot, are heated to 80 ~ 85 DEG C, are stirred to and dissolve completely, obtain material B;
S3, by material A and material B suction emulsifying pot, open homogenizing, homogenizing 5 ~ 10min, insulated and stirred 10 ~ 20min;
S4, be cooled to 40 ~ 45 DEG C; add 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum-1, lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, six peptides-3, orange blossom elite, Gentiana lutea extract, milk protein, tranamic acid, phenoxyethanol and essence; stir; get final product discharging, obtained anti-wrinkle essence.
Further, the mixing speed of described stirring is 40 ~ 50r/min.
Therefore, compared with prior art, advantage of the present invention is:
(1) anti-wrinkle essence of the present invention contains the multiple natural extracts such as lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, orange blossom elite and Gentiana lutea extract, can efficiently moisturizing, moisturizing, to skin supply nutrition, promote skin metabolism, effectively calm down microgroove, reduce wrinkle, slowing down skin aging, improves cutis laxa sagging, and bright skin compacts, and long-acting moisturizing, skin beauty water is moistened smooth, high resilience, promote skin year slight.
(2) anti-wrinkle essence safety and stability of the present invention, good penetrability, easily absorbs, and uses rear face salubrious not sticky; And the preparation method of anti-wrinkle essence of the present invention is simple, condition is controlled, process stabilizing, can be applicable.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, anti-wrinkle essence of the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
In anti-wrinkle essence described in the embodiment of the present invention, the information such as producer and article No. of part material is as follows:
embodiment 1, anti-wrinkle essence of the present invention and preparation thereof
formula:be made up of the raw material of following weight percent meter: Cyclomethicone 6%, butanediol 6%, polydimethylsiloxane 3%, polyglutamic acid sodium 2%, glycerol 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, erithritol 1%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 1%, biological carbohydrate gum-10.8%, xylitol 0.8%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.8%, lactobacillus/Punica granatum L. tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, Asterias amurensis Lutken elite 0.5%, six peptides-30.6%, orange blossom elite 0.5%, Gentiana lutea extract 0.5%, arbutin 0.2%, milk protein 0.2%, tranamic acid 0.1%, methyl hydroxybenzoate 0.01%, phenoxyethanol 0.01%, essence 0.0015% and water 68.8785%.
preparation method:
S1, by Cyclomethicone, polydimethylsiloxane and C20-22 alcohol phosphate ester/C20-22 alcohol, add in oil phase pot, be heated to 80 DEG C, be stirred to and dissolve completely, obtain material A;
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerol, propylene glycol, Natrulon H-10, dipropylene glycol, erithritol, xylitol, arbutin and methyl hydroxybenzoate add in aqueous phase pot, are heated to 80 DEG C, are stirred to and dissolve completely, obtain material B;
S3, by material A and material B suction emulsifying pot, open homogenizing, homogenizing 10min, insulated and stirred 15min;
S4, be cooled to 40 DEG C; add 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum-1, lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, six peptides-3, orange blossom elite, Gentiana lutea extract, milk protein, tranamic acid, phenoxyethanol and essence; stir; get final product discharging, obtained anti-wrinkle essence.
The mixing speed of described stirring is 45r/min.
embodiment 2, anti-wrinkle essence of the present invention and preparation thereof
formula:be made up of the raw material of following weight percent meter: Cyclomethicone 4%, butanediol 4%, polydimethylsiloxane 6%, polyglutamic acid sodium 1%, glycerol 3%, propylene glycol 0.5%, Natrulon H-10 3%, dipropylene glycol 0.5%, erithritol 2%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 0.5%, biological carbohydrate gum-11.5%, xylitol 0.5%, C20-22 alcohol phosphate ester/C20-22 alcohol 1.5%, lactobacillus/Punica granatum L. tunning extract 0.3%, arctic Ascophyllum nodosum elite 1%, Asterias amurensis Lutken elite 0.3%, six peptides-31%, orange blossom elite 0.3%, Gentiana lutea extract 1%, arbutin 0.1%, milk protein 0.6%, tranamic acid 0.05%, methyl hydroxybenzoate 0.01%, phenoxyethanol 0.05%, essence 0.01% and water 67.28%.
preparation method:
S1, by Cyclomethicone, polydimethylsiloxane and C20-22 alcohol phosphate ester/C20-22 alcohol, add in oil phase pot, be heated to 85 DEG C, be stirred to and dissolve completely, obtain material A;
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerol, propylene glycol, Natrulon H-10, dipropylene glycol, erithritol, xylitol, arbutin and methyl hydroxybenzoate add in aqueous phase pot, are heated to 85 DEG C, are stirred to and dissolve completely, obtain material B;
S3, by material A and material B suction emulsifying pot, open homogenizing, homogenizing 5min, insulated and stirred 20min;
S4, be cooled to 45 DEG C; add 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum-1, lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, six peptides-3, orange blossom elite, Gentiana lutea extract, milk protein, tranamic acid, phenoxyethanol and essence; stir; get final product discharging, obtained anti-wrinkle essence.
The mixing speed of described stirring is 40r/min.
embodiment 3, anti-wrinkle essence of the present invention and preparation thereof
formula:be made up of the raw material of following weight percent meter: Cyclomethicone 8%, butanediol 8%, polydimethylsiloxane 2%, polyglutamic acid sodium 4%, glycerol 0.5%, propylene glycol 3%, Natrulon H-10 0.5%, dipropylene glycol 2%, erithritol 0.5%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 2%, biological carbohydrate gum-10.5%, xylitol 1.5%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.5%, lactobacillus/Punica granatum L. tunning extract 1%, arctic Ascophyllum nodosum elite 0.3%, Asterias amurensis Lutken elite 1%, six peptides-30.3%, orange blossom elite 1%, Gentiana lutea extract 0.3%, arbutin 0.6%, milk protein 0.1%, tranamic acid 0.3%, methyl hydroxybenzoate 0.05%, phenoxyethanol 0.01%, essence 0.01% and water 62.03%.
preparation method:
S1, by Cyclomethicone, polydimethylsiloxane and C20-22 alcohol phosphate ester/C20-22 alcohol, add in oil phase pot, be heated to 80 DEG C, be stirred to and dissolve completely, obtain material A;
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerol, propylene glycol, Natrulon H-10, dipropylene glycol, erithritol, xylitol, arbutin and methyl hydroxybenzoate add in aqueous phase pot, are heated to 80 DEG C, are stirred to and dissolve completely, obtain material B;
S3, by material A and material B suction emulsifying pot, open homogenizing, homogenizing 10min, insulated and stirred 10min;
S4, be cooled to 40 DEG C; add 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum-1, lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, six peptides-3, orange blossom elite, Gentiana lutea extract, milk protein, tranamic acid, phenoxyethanol and essence; stir; get final product discharging, obtained anti-wrinkle essence.
The mixing speed of described stirring is 50r/min.
embodiment 4, anti-wrinkle essence of the present invention and preparation thereof
formula:be made up of the raw material of following weight percent meter: Cyclomethicone 4%, butanediol 4%, polydimethylsiloxane 8%, polyglutamic acid sodium 1%, glycerol 4%, propylene glycol 0.5%, Natrulon H-10 4%, dipropylene glycol 4%, erithritol 0.5%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 4%, biological carbohydrate gum-10.5%, xylitol 3%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.5%, lactobacillus/Punica granatum L. tunning extract 0.3%, arctic Ascophyllum nodosum elite 0.3%, Asterias amurensis Lutken elite 0.3%, six peptides-30.3%, orange blossom elite 0.3%, Gentiana lutea extract 0.3%, arbutin 1%, milk protein 1%, tranamic acid 1%, methyl hydroxybenzoate 0.01%, phenoxyethanol 0.1%, essence 0.05% and water 57.04%.
Preparation method is with embodiment 1.
embodiment 5, anti-wrinkle essence of the present invention and preparation thereof
formula:be made up of the raw material of following weight percent meter: Cyclomethicone 10%, butanediol 10%, polydimethylsiloxane 2%, polyglutamic acid sodium 5%, glycerol 0.5%, propylene glycol 4%, Natrulon H-10 0.5%, dipropylene glycol 0.5%, erithritol 4%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 0.5%, biological carbohydrate gum-13%, xylitol 3%, C20-22 alcohol phosphate ester/C20-22 alcohol 3%, lactobacillus/Punica granatum L. tunning extract 2%, arctic Ascophyllum nodosum elite 2%, Asterias amurensis Lutken elite 2%, six peptides-32%, orange blossom elite 2%, Gentiana lutea extract 2%, arbutin 0.1%, milk protein 0.1%, tranamic acid 0.05%, methyl hydroxybenzoate 0.1%, phenoxyethanol 0.01%, essence 0.01% and water 41.63%.
Preparation method is with embodiment 1.
Through inspection, the anti-wrinkle essence that the embodiment of the present invention 1 ~ 5 obtains meets the pertinent regulations requirement of QB/T2660-2004, and sense index (color and luster, fragrance, structure) meets industry regulation, and physical and chemical index (pH, heat-resisting, cold-resistant, active matter) meets industry regulation.
comparative example 1,
formula:be made up of the raw material of following weight percent meter: Cyclomethicone 6%, butanediol 6%, polydimethylsiloxane 3%, polyglutamic acid sodium 2%, glycerol 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, erithritol 1%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 1%, biological carbohydrate gum-10.8%, xylitol 0.8%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.8%, six peptides-31.2%, orange blossom elite 1%, Gentiana lutea extract 1%, arbutin 0.2%, milk protein 0.2%, tranamic acid 0.1%, methyl hydroxybenzoate 0.01%, phenoxyethanol 0.01%, essence 0.0015% and water 68.8785%.
Preparation method is with reference to embodiment 1.
comparative example 2,
formula:be made up of the raw material of following weight percent meter: butanediol 6%, polydimethylsiloxane 9%, polyglutamic acid sodium 2%, glycerol 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 1%, xylitol 1.8%, C20-22 alcohol phosphate ester/C20-22 alcohol 1.6%, lactobacillus/Punica granatum L. tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, Asterias amurensis Lutken elite 0.5%, six peptides-30.6%, orange blossom elite 0.5%, Gentiana lutea extract 0.5%, arbutin 0.3%, milk protein 0.2%, methyl hydroxybenzoate 0.01%, phenoxyethanol 0.01%, essence 0.0015% and water 68.8785%.
Preparation method is with reference to embodiment 1.
test example one, Product Safety evaluation (experiment of human body skin patch)
One, trial target: the anti-wrinkle essence that embodiment 1 ~ 5, comparative example 1 ~ 2 prepare
Tested crowd's number: 70 people, women
Age: between 30 ~ 50 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: 7 groups, often organize 10 people, 28 ± 2 years old mean age.
Two, patch method: select qualified speckle examination device, with closed patch experiment method, tested material being about 0.020mL ~ 0.025mL drips in speckle examination device, external special adhesive tape is covered on experimenter back, tested material is removed after 24 hours, within after removing respectively 0.5,6,12,24,48 hour, observe dermoreaction, according to its result of dermoreaction grade scale record in " cosmetics health specification ".
Three, experimental result: human skin patch result shows: each group experimenter is by the patch test of the anti-wrinkle essence of embodiment 1 ~ 5, comparative example 1 ~ 2, dermoreaction is observed at 0.5,6,12,24,48 hour, wherein there is skin adverse reaction in 0 example, the anti-wrinkle essence use safety described in explanation.
test example two, product effect assessment
part I:
One, trial target: the anti-wrinkle essence that embodiment 1 prepares
Two, tested crowd
Sex number: female, 30 people
Age: between 35 ~ 45 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Three, method of testing: adopt the skin elasticity CotometerMPA580 main frame that German Courage+Khazaka company (German CK company) manufactures, the probe used is ReviscometerRV600 elastic fibrous tissue test probe, surveys and averages for five times.Test zone: place between the eyebrows middle is 2cm forehead region, lower lip middle down 2cm chin area, the left and right cheek region of nose and pupil intersection place up.First measure the blank value (R2, R5, R7) of 30min after tested region clean, then specify that experimenter adheres to using above-mentioned trial target every day sooner or later, test test zone skin elasticity index R2, R5, R7 value (in test process, negative pressure is constant is 450mbar) after 1 week, 2 weeks, 3 weeks, 4 weeks respectively.
Index illustrates: skin elasticity index R2, R5, R7 are more close to 1, and the elasticity of skin is better.
R2=Ua/Uf;R5=Ur/Ue;R7=Ur/Uf
Uf---skin maximum tension amount
Ue---constant negative pressure is added to after on skin, the amount of tension of skin during 0.1 second, positioning elastic part amount of tension.
Ur---cancel after negative pressure, skin will restore to the original state rapidly state, is divided into elastic score value Ur equally, namely cancels negative pressure after 0.1 second, the recovery value of skin and visco-elastic portions value, or claim plastic value.
Ua---from cancelling the recovery value of negative pressure to skin when follow-on test skin surface adds negative pressure more next time.
Four, test result is as following table 1.
Table 1 embodiment 1 anti-wrinkle essence table with test results
From upper table 1: use anti-wrinkle essence first week rear R2, R5, R7 of embodiment 1 to increase to some extent, within 4th week, R2, R5, R7 all rise obviously, and R2, R5, R7 value levels off to 1, the skin elasticity index of experimenter has very large lifting, as can be seen here, this anti-wrinkle essence has increases skin elasticity, antidotal effect.
part II:
One, trial target: embodiment 1 ~ 5, anti-wrinkle essence prepared by comparative example 1 ~ 2
Two, tested crowd
Sex number: female, 210 people
Age: between 35 ~ 55 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: be divided into 7 groups, often organize 30 people, 43 ± 2 years old mean age.
Three, method of testing: respectively use-case 1 ~ 5, anti-wrinkle essence prepared by comparative example 1 ~ 2, observes and experiences result of use.Using method: after experimenter cleans face, get appropriate above-mentioned anti-wrinkle essence in the centre of the palm, uniform application is in face, and be massaged into absorption gently, the every day of each use sooner or later once, adhere to use one month, at least check weekly once to understand with or without whole body and local untoward reaction, and itemized record result.
Four, testing evaluation result is as follows:
(one month) on probation feedback conclusive table of table 2 embodiment 1 anti-wrinkle essence
(one month) on probation feedback conclusive table of table 3 embodiment 2 anti-wrinkle essence
(one month) on probation feedback conclusive table of table 4 embodiment 3 anti-wrinkle essence
(one month) on probation feedback conclusive table of table 5 embodiment 4 anti-wrinkle essence
(one month) on probation feedback conclusive table of table 6 embodiment 5 anti-wrinkle essence
(one month) on probation feedback conclusive table of table 7 comparative example 1 anti-wrinkle essence
(one month) on probation feedback conclusive table of table 8 comparative example 2 anti-wrinkle essence
(1) from upper table 2 ~ 6, anti-wrinkle essence the liking and approving extensively by experimenter of the embodiment of the present invention 1 ~ 5, experimenter all represents anti-wrinkle essence good penetrability of the present invention, easy absorption, use rear face salubrious not sticky, moisturizing, moistening effect are good, to skin supply nutrition, promote skin metabolism, effectively calm down microgroove, reduce wrinkle, slowing down skin aging, and long-acting moisturizing, skin beauty water is moistened smooth, flexible.The highest with the degree of recognition of embodiment 1 anti-wrinkle essence in embodiment 1 ~ 5, therefore embodiment 1 is preferred embodiment.
(2) from upper table 7 ~ 8, comparative example 1 and comparative example 2 essence lack some component in re-surface intensive wrinkle correct formula of liquid of the present invention, its result of use is all not as embodiment 1 ~ 5, illustrate that re-surface intensive wrinkle correct formula of liquid of the present invention is not obtained by the simple combination of each component, then further illustrate between each component of formula of the present invention and there is synergism.
There is not people to occur allergic phenomena in whole experimenter simultaneously, all do not occur the situations such as skin pruritus, twinge, redness yet.Therefore, the gentle safety of anti-wrinkle essence of the present invention, can life-time service.
Above-described embodiment is illustrative principle of the present invention and effect thereof only, but not for limiting the present invention.Any person skilled in the art scholar all without prejudice under spirit of the present invention and category, can modify above-described embodiment or changes.Therefore, such as have in art usually know the knowledgeable do not depart from complete under disclosed spirit and technological thought all equivalence modify or change, must be contained by claim of the present invention.
Claims (5)
1. an anti-wrinkle essence, it is characterized in that, comprise the raw material of following weight percent meter: Cyclomethicone 4 ~ 10%, butanediol 4 ~ 10%, polydimethylsiloxane 2 ~ 8%, polyglutamic acid sodium 1 ~ 5%, glycerol 0.5 ~ 4%, propylene glycol 0.5 ~ 4%, Natrulon H-10 0.5 ~ 4%, dipropylene glycol 0.5 ~ 4%, erithritol 0.5 ~ 4%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 0.5 ~ 4%, biological carbohydrate gum-10.5 ~ 3%, xylitol 0.5 ~ 3%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.5 ~ 3%, lactobacillus/Punica granatum L. tunning extract 0.3 ~ 2%, arctic Ascophyllum nodosum elite 0.3 ~ 2%, Asterias amurensis Lutken elite 0.3 ~ 2%, six peptides-30.3 ~ 2%, orange blossom elite 0.3 ~ 2%, Gentiana lutea extract 0.3 ~ 2%, arbutin 0.1 ~ 1%, milk protein 0.1 ~ 1%, tranamic acid 0.05 ~ 1%, methyl hydroxybenzoate 0.01 ~ 0.1%, phenoxyethanol 0.01 ~ 0.1%, essence 0.0002 ~ 0.05% and water 40 ~ 70%.
2. anti-wrinkle essence as claimed in claim 1, it is characterized in that, comprise the raw material of following weight percent meter: Cyclomethicone 4 ~ 8%, butanediol 4 ~ 8%, polydimethylsiloxane 2 ~ 6%, polyglutamic acid sodium 1 ~ 4%, glycerol 0.5 ~ 3%, propylene glycol 0.5 ~ 3%, Natrulon H-10 0.5 ~ 3%, dipropylene glycol 0.5 ~ 2%, erithritol 0.5 ~ 2%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 0.5 ~ 2%, biological carbohydrate gum-10.5 ~ 1.5%, xylitol 0.5 ~ 1.5%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.5 ~ 1.5%, lactobacillus/Punica granatum L. tunning extract 0.3 ~ 1%, arctic Ascophyllum nodosum elite 0.3 ~ 1%, Asterias amurensis Lutken elite 0.3 ~ 1%, six peptides-30.3 ~ 1%, orange blossom elite 0.3 ~ 1%, Gentiana lutea extract 0.3 ~ 1%, arbutin 0.1 ~ 0.6%, milk protein 0.1 ~ 0.6%, tranamic acid 0.05 ~ 0.3%, methyl hydroxybenzoate 0.01 ~ 0.05%, phenoxyethanol 0.01 ~ 0.05%, essence 0.0002 ~ 0.01% and water 60 ~ 70%.
3. anti-wrinkle essence as claimed in claim 2, it is characterized in that, be made up of the raw material of following weight percent meter: Cyclomethicone 6%, butanediol 6%, polydimethylsiloxane 3%, polyglutamic acid sodium 2%, glycerol 2%, propylene glycol 1.5%, Natrulon H-10 1.5%, dipropylene glycol 1%, erithritol 1%, 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers 1%, biological carbohydrate gum-10.8%, xylitol 0.8%, C20-22 alcohol phosphate ester/C20-22 alcohol 0.8%, lactobacillus/Punica granatum L. tunning extract 0.5%, arctic Ascophyllum nodosum elite 0.6%, Asterias amurensis Lutken elite 0.5%, six peptides-30.6%, orange blossom elite 0.5%, Gentiana lutea extract 0.5%, arbutin 0.2%, milk protein 0.2%, tranamic acid 0.1%, methyl hydroxybenzoate 0.01%, phenoxyethanol 0.01%, essence 0.0015% and water 68.8785%.
4. prepare as arbitrary in claim 1 ~ 3 as described in the method for anti-wrinkle essence, it is characterized in that, comprise the following steps:
S1, by Cyclomethicone, polydimethylsiloxane and C20-22 alcohol phosphate ester/C20-22 alcohol, add in oil phase pot, be heated to 80 ~ 85 DEG C, be stirred to and dissolve completely, obtain material A;
S2, Jiang Shui, butanediol, polyglutamic acid sodium, glycerol, propylene glycol, Natrulon H-10, dipropylene glycol, erithritol, xylitol, arbutin and methyl hydroxybenzoate add in aqueous phase pot, are heated to 80 ~ 85 DEG C, are stirred to and dissolve completely, obtain material B;
S3, by material A and material B suction emulsifying pot, open homogenizing, homogenizing 5 ~ 10min, insulated and stirred 10 ~ 20min;
S4, be cooled to 40 ~ 45 DEG C; add 2-(Acryloyloxy)ethanol/sodium acryloyldimethyl taurate copolymers, biological carbohydrate gum-1, lactobacillus/Punica granatum L. tunning extract, arctic Ascophyllum nodosum elite, Asterias amurensis Lutken elite, six peptides-3, orange blossom elite, Gentiana lutea extract, milk protein, tranamic acid, phenoxyethanol and essence; stir; get final product discharging, obtained anti-wrinkle essence.
5. the preparation method of anti-wrinkle essence as claimed in claim 4, it is characterized in that, the mixing speed of described stirring is 40 ~ 50r/min.
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102793656A (en) * | 2012-08-10 | 2012-11-28 | 彭再辉 | Firming anti-wrinkle essence cosmetic and preparation method |
CN104352418A (en) * | 2014-10-20 | 2015-02-18 | 东莞市阿比亚能源科技有限公司 | Anti-ageing essence |
CN104622907A (en) * | 2013-11-14 | 2015-05-20 | 百岳特生物科技(上海)有限公司 | Use of starfish extract for preparing composition for promoting collagen proliferation |
CN104814898A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Lifting and tightening mask solution, manufacturing method and lifting and tightening mask |
-
2015
- 2015-10-19 CN CN201510673049.8A patent/CN105125476B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102793656A (en) * | 2012-08-10 | 2012-11-28 | 彭再辉 | Firming anti-wrinkle essence cosmetic and preparation method |
CN104622907A (en) * | 2013-11-14 | 2015-05-20 | 百岳特生物科技(上海)有限公司 | Use of starfish extract for preparing composition for promoting collagen proliferation |
CN104352418A (en) * | 2014-10-20 | 2015-02-18 | 东莞市阿比亚能源科技有限公司 | Anti-ageing essence |
CN104814898A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Lifting and tightening mask solution, manufacturing method and lifting and tightening mask |
Non-Patent Citations (2)
Title |
---|
夏文晴: "《可以吃的天然美肤面膜》", 30 September 2014, 北京联合出版公司 * |
董益阳主编: "《化妆品知识问答》", 30 April 2011, 中国标准出版社 * |
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Address after: Huadu District, Guangdong city of Guangzhou province 510880 Flower Town Qiyuan Road No. 28 Applicant after: Guangzhou Kema biotechnology Polytron Technologies Inc Address before: Hua Town, Huadu District, Guangdong Province, 510880 Avenue, Guangzhou City Applicant before: Kerma (unit of kinetic energy) bio tech ltd, Guangzhou |
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GR01 | Patent grant | ||
GR01 | Patent grant |