CN109998953A - It is a kind of for improving the polypeptide Essence of skin quality - Google Patents
It is a kind of for improving the polypeptide Essence of skin quality Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses a kind of for improving the polypeptide Essence of skin quality, its component are as follows: propylene glycol, diglycerol, glycerol, butanediol, niacinamide, polyethylene glycol-8, PEG/PPG-17/6 copolymer, hamamelis water, glyceryl acrylate/acrylic copolymer, Gantrez AN-119, palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3, dipeptides diaminobutyryl benzyl amide diacetin, 1, 2- hexylene glycol, glycine betaine, tapioca, ammonium acryloyl taurate/VP copolymer, carbomer, acetyl chitosamine, white willow bark extract, papain, Sodium Hyaluronate, pungent glycol, collagen, Cremophor RH40, hydroxyethyl cellulose, oligopeptides -1, Wild soybean seed extract, carnosine, EDETATE SODIUM, it is pungent Acyl hydroximic acid, Tujue's rose caul-fat, water.The present invention can wake up skin vigor using the compact molecule of polypeptide as primary raw material, maintain elasticity of skin, promote compact, improvement microgroove, and bright color improves skin quality, shining skin youth state living.
Description
Technical field
The invention belongs to technology of fine chemicals, and in particular to a kind of for improving the polypeptide Essence of skin quality.
Background technique
With advancing age and the increasing of environmental pollution and life stress, the skin aging of people are more and more obvious,
Become to dry, lack flexibility, generate wrinkle and color is obscure.Cosmetics and skincare product is also increasingly valued by people.
Essence is a kind of common cosmetics and skincare product, skin care moisturizing is used in early days, in recent years, with people's living standard
Raising, it is more and more stronger for the protective awareness of skin, more exacerbate people for the demand of essence function, including essence
Moisturizing effect, inhibit skin mushroom regeneration etc..Essence is will be from certain animal visceras or tissue, natural plants or medium-height grass
Extracting and developing, the innate efficacy ingredient being purified or bioactive substance or skin battalion in medicine, marine organisms, microorganism etc.
Support element etc., be added in certain high-quality liquid make-ups according to a certain percentage can be prepared into different beauty functions with
The Cosmetic Essence of skin anti-aging effect, this is in current cosmetics and skin anti-aging external preparation most by consumer
One of favor and the dosage form welcome.
Polypeptide is a-amino acid with the compound that peptide bond links together and is formed, it is also the centre of protein hydrolysis
Product.The compound as made of two amino acid molecular dehydrating condensations is called dipeptides, similarly analogizes also tripeptides, tetrapeptide, pentapeptide
Deng.Usually the compound as made of three or three or more amino acid molecular dehydrating condensations, which can become, is polypeptide.
So-called polypeptide, it is a kind of compound of the molecular structure between amino acid and protein.It is by amino acid structure
At, but it is again different with protein, belong to the intermediate material between them.Amino acid can be interconnected with peptide bond each other
Compound is referred to as peptide.A kind of amino acid that peptide the contains thus referred to as oligopeptides less than 10, be more than is known as polypeptide, amino acid
Polypeptide for more than 50 or more is known as protein.Polypeptide bioactivity is high, it is adjustable various physiological activities and biochemical reaction.
Polypeptide is applied in the essence for improving skin quality currently, there has been no mature products.
Summary of the invention
Goal of the invention: in view of the deficiencies of the prior art, the polypeptide essence that the present invention provides a kind of for improving skin quality
Magnificent liquid.
Technical solution, it is provided by the present invention for improving the polypeptide Essence of skin quality, component are as follows: propylene glycol, double sweet
Oil, glycerol, butanediol, niacinamide, polyethylene glycol-8, PEG/PPG-17/6 copolymer, hamamelis water, glycerol acrylic acid
Ester/acrylic copolymer, Gantrez AN-119, palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3, dipeptides two
Aminobutyryl benzyl amide diacetin, 1,2- hexylene glycol, glycine betaine, tapioca, ammonium acryloyldime-thyltaurate/VP are total
Polymers, carbomer, acetyl chitosamine, white willow bark extract, papain, Sodium Hyaluronate, pungent glycol, collagen, PEG-
40 rilanit specials, hydroxyethyl cellulose, oligopeptides -1, Wild soybean seed extract, carnosine, EDETATE SODIUM, decoyl hydroximic acid, Tujue
Rose caul-fat, water.
Wherein, the chemical name of glycerol is a kind of thick liquid colourless, odorless, sweet in flavor, has very strong suction glycerine
It is aqueous, it is applied on skin, skin wet can be made, be unlikely to dry and cracked.The appearance of glycerol is a kind of transparent and sticky liquid, is inhaled
It receives quickly, to the skin of season decortication, small pox stays the skin of scar, and sensibility skin etc. is all moisturizing good merchantable brand, skin can be made to protect
Softness is held, high resilience is not damaged by dust, weather etc. and dried, plays the role of preventing skin frostbite.Since glycerol can
To increase the moisture content in tissue, it is possible to increase the locomitivity of human body under high-heat environment.
Wherein, butanediol plays a part of moisturizing to skin, because butanediol is small molecule moisturizing ingredient, in addition to protecting
It is wet effectively bacterium to be inhibited to generate.The safety for having a lot of experiments that can prove butanediol for cosmetics, such as:
It is primary every other day to smear when carrying out interruption smearing to human body, it totally 16 days, in all 200 people for participating in test, does not all send out
Existing any irritating inflammation.In addition, butanediol, which is added in toothpaste, carried out oral cavity experiment, butanediol is as a result all shown
It is a kind of non-stimulated, and the very high chemical substance of safety.
Wherein, hyaluronic acid acts on skin surface, and 1, one layer of ventilative film can be formed in skin surface, it make skin light
It is sliding wet, and the intrusion of alien bacteria, dust, ultraviolet light can be obstructed, protect the skin from infringement；2, hyaluronic acid can penetrate into very
Skin, have mild dilation capillary, increase blood circulation, improve intermediate supersession, promote skin-nourishing absorption, have compared with
Strong wrinkle-chasing function, can increase skin elasticity, delay skin aging；3, hyaluronic acid can also promote the proliferation of epidermal cell and divide
Change, scavenging activated oxygen, can prevent and repair skin injury；4, the aqueous solution of hyaluronic acid has very high viscosity, can make water
Mutually thicken；5, the lotion uniform and smooth after mutually emulsifying with oils, essential oil class has stable emulsion effect.
Wherein, EDETATE SODIUM, which is called, does disodium ethylene diamine tetraacetate, is a kind of good compounding agent in chemistry, there are six it
Coordination atom, the complex of formation are called chelating object, and the present invention is used as preservative, anti-oxidant synergist.
Specifically, main component of the present invention and content are as follows:
Niacinamide 2~3%；
Palmityl hexapeptide -14 1~1%；
Tripeptides -1, Argireline, pentapeptide -3 1~1%；
Dipeptides diaminobutyryl benzyl amide diacetin 0.6~1%；
Acetyl chitosamine 0.2~0.5%；
White willow bark extract 0.2~0.5%；
Papain 0.2~0.5%；
Sodium Hyaluronate 0.1~0.2%；
Collagen 0.1~0.2%；
Oligopeptides -1 0.03~0.05%；
Carnosine 0.01~0.02%.
It is further preferred, main component and content are as follows:
Niacinamide 2%；
Palmityl hexapeptide -14 1%；
Tripeptides -1, Argireline, pentapeptide -3 1%；
Dipeptides diaminobutyryl benzyl amide diacetin 0.6%；
Acetyl chitosamine 0.2%；
White willow bark extract 0.2%；
Papain 0.2；
Sodium Hyaluronate 0.1%；
Collagen 0.1%；
Oligopeptides -1 0.03%；
Carnosine 0.01%.
Specifically, remaining component of the invention and content are as follows:
Polyethylene glycol-8 0.2~0.5%；
PEG/PPG-17/6 copolymer 0.2~0.5%；
Hamamelis water 0.5~0.1%；
Glyceryl acrylate/acrylic copolymer 0.2~0.5%；
Gantrez AN-119 0.2~0.5%；
1,2- hexylene glycol 0.5~0.8%；
Glycine betaine 0.2~0.5%；
Tapioca 0.1~0.2%；
Ammonium acryloyl taurate/VP copolymer 0.2~0.5%；
Carbomer 0.1~0.2%；
Pungent glycol 0.1~0.2%；
Cremophor RH40 0.2~0.8%；
Hydroxyethyl cellulose 0.01~0.02%；
Wild soybean seed extract 0.2~0.3%；
EDETATE SODIUM 0.2~0.3%；
Decoyl hydroximic acid 0.2~0.3%；
Tujue's rose caul-fat 0.2~0.3%；
Water surplus.
It is further preferred, remaining component and content are as follows:
Polyethylene glycol-8 0.2%；
PEG/PPG-17/6 copolymer 0.2%；
Hamamelis water 0.5%；
Glyceryl acrylate/acrylic copolymer 0.2%；
Gantrez AN-119 0.2%；
1,2- hexylene glycol 0.5%；
Glycine betaine 0.2%；
Tapioca 0.1%；
Ammonium acryloyl taurate/VP copolymer 0.2%；
Carbomer 0.1%；
Pungent glycol 0.1%；
Cremophor RH40 0.2%；
Hydroxyethyl cellulose 0.01%；
Wild soybean seed extract 0.2%；
EDETATE SODIUM 0.2%；
Decoyl hydroximic acid 0.2%；
Tujue's rose caul-fat 0.2%；
Water surplus.
A preferred embodiment of the invention are as follows: niacinamide 2%；Palmityl hexapeptide -14 1%；Tripeptides -1, acetyl group hexapeptide -
8, pentapeptide -3 1%；Dipeptides diaminobutyryl benzyl amide diacetin 0.6%；Acetyl chitosamine 0.2%；White willow bark extracts
Object 0.2%；Papain 0.2；Sodium Hyaluronate 0.1%；Collagen 0.1%；Oligopeptides -1 0.03%；Carnosine 0.01%；Poly- second
Glycol -8 0.2%；PEG/PPG-17/6 copolymer 0.2%；Hamamelis water 0.5%；Glyceryl acrylate/acrylic acid is total
Polymers 0.2%；Gantrez AN-119 0.2%；1,2- hexylene glycol 0.5%；Glycine betaine 0.2%；Tapioca 0.1%；Acryloyl
Dimethyltaurine ammonium/VP copolymer 0.2%；Carbomer 0.1%；Pungent glycol 0.1%；Cremophor RH40 0.2%；
Hydroxyethyl cellulose 0.01%；Wild soybean seed extract 0.2%；EDETATE SODIUM 0.2%；Decoyl hydroximic acid 0.2%；Tujue's rose
Common vetch caul-fat 0.2%；Water surplus.
The present invention also provides above-mentioned for improving the preparation method of the polypeptide Essence of skin quality, which is characterized in that including
Following steps: first by PEG/PPG-17/6 copolymer, glyceryl acrylate/acrylic copolymer, Gantrez AN-119, acryloyl
Dimethyltaurine ammonium/VP copolymer after being added to the water immersion 30-60 minutes, stirs heating 80-90 degree；
Again by propylene glycol, water, diglycerol, glycerol, butanediol, niacinamide, polyethylene glycol-8, hamamelis water, 1,2-
Hexylene glycol, glycine betaine, tapioca, carbomer, acetyl chitosamine, white willow bark extract, papain, pungent glycol, glue
Original, Cremophor RH40, hydroxyethyl cellulose, Wild soybean seed extract, EDETATE SODIUM, decoyl hydroximic acid, Tujue rose
Caul-fat, stirring heating 80-90 degree, is added above-mentioned system after stirring evenly；
Then pH value is adjusted between 5-6, be added palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3,
Dipeptides diaminobutyryl benzyl amide diacetin, oligopeptides -1, carnosine, Sodium Hyaluronate, stir evenly to get.
Further, preferred preparation method includes the following steps: PEG/PPG-17/6 copolymer, glycerol propylene first
Acid esters/acrylic copolymer, ammonium acryloyl taurate/VP copolymer, is added to the water 60 points of immersion at Gantrez AN-119
Zhong Hou, 90 degree of stirring heating；
Again by propylene glycol, water, diglycerol, glycerol, butanediol, niacinamide, polyethylene glycol-8, hamamelis water, 1,2-
Hexylene glycol, glycine betaine, tapioca, carbomer, acetyl chitosamine, white willow bark extract, papain, pungent glycol, glue
Original, Cremophor RH40, hydroxyethyl cellulose, Wild soybean seed extract, EDETATE SODIUM, decoyl hydroximic acid, Tujue rose
Caul-fat, 90 degree of stirring heating, is added above-mentioned system after stirring evenly；
Then pH value is adjusted between 5-6, be added palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3,
Dipeptides diaminobutyryl benzyl amide diacetin, oligopeptides -1, carnosine, Sodium Hyaluronate, stir evenly to get.
The utility model has the advantages that polypeptide biology essence provided by the invention, epidermal growth factor oligopeptides -1 and acid fibroblast are raw
Long -13 maintenance epidermis of factor oligopeptides rebuilds skin barrier function, and healing of wound is crease-resistant, anti-ageing；For microgroove, it is dim it is heavy, cutin is thin,
Pore is coarse, dry skin designs.Using the compact molecule of polypeptide as primary raw material, skin vigor can be waken up, elasticity of skin is maintained, mentions
Compact, improvement microgroove is risen, bright color improves skin quality, shining skin youth state living.
Present invention long-time service can improve skin condition, high power moisturizing, enhancing elasticity of skin.
Specific embodiment:
Preparation method
First by PEG/PPG-17/6 copolymer, glyceryl acrylate/acrylic copolymer, PVM/MA copolymer, acryloyl
Dimethyltaurine ammonium/VP copolymer after being added to the water immersion 30-60 minutes, stirs heating 80-90 degree；
Again by propylene glycol, water, diglycerol, glycerol, butanediol, niacinamide, polyethylene glycol-8, hamamelis
(HAMAMELIS VIRGINIANA) water, 1,2- hexylene glycol, glycine betaine, tapioca, carbomer, acetyl chitosamine, white willow
(SALIX ALBA) bark extract, papain, pungent glycol, collagen, Cremophor RH40, hydroxyethyl cellulose,
Wild soybean (GLYCINE SOJA) seed extract, EDETATE SODIUM, decoyl hydroximic acid, Tujue rose (ROSA DAMASCENA) flower
Oil, stirring heating 80-90 degree, is added above-mentioned system after stirring evenly；
Then pH value is adjusted between 5-6, be added palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3,
Dipeptides diaminobutyryl benzyl amide diacetin, oligopeptides -1, carnosine, Sodium Hyaluronate, stir evenly to get.
Embodiment 1 (formula 1)
Niacinamide 2%；
Palmityl hexapeptide -14 1%；
Tripeptides -1, Argireline, pentapeptide -3 1%；
Dipeptides diaminobutyryl benzyl amide diacetin 0.6%；
Acetyl chitosamine 0.2%；
White willow bark extract 0.2%；
Papain 0.2；
Sodium Hyaluronate 0.1%；
Collagen 0.1%；
Oligopeptides -1 0.03%；
Carnosine 0.01%.
Polyethylene glycol-8 0.2%；
PEG/PPG-17/6 copolymer 0.2%；
Hamamelis water 0.5%；
Glyceryl acrylate/acrylic copolymer 0.2%；
Gantrez AN-119 0.2%；
1,2- hexylene glycol 0.5%；
Glycine betaine 0.2%；
Tapioca 0.1%；
Ammonium acryloyl taurate/VP copolymer 0.2%；
Carbomer 0.1%；
Pungent glycol 0.1%；
Cremophor RH40 0.2%；
Hydroxyethyl cellulose 0.01%；
Wild soybean seed extract 0.2%；
EDETATE SODIUM 0.2%；
Decoyl hydroximic acid 0.2%；
Tujue's rose caul-fat 0.2%；
Water surplus.
Embodiment 2 (formula 2)
Niacinamide 2~3%；
Palmityl hexapeptide -14 1~1%；
Tripeptides -1, Argireline, pentapeptide -3 1~1%；
Dipeptides diaminobutyryl benzyl amide diacetin 0.6~1%；
Acetyl chitosamine 0.2~0.5%；
White willow bark extract 0.2~0.5%；
Papain 0.2~0.5%；
Sodium Hyaluronate 0.1~0.2%；
Collagen 0.1~0.2%；
Oligopeptides -1 0.03~0.05%；
Carnosine 0.01~0.02%.
Polyethylene glycol-8 0.2~0.5%；
PEG/PPG-17/6 copolymer 0.2~0.5%；
Hamamelis water 0.5~0.1%；
Glyceryl acrylate/acrylic copolymer 0.2~0.5%；
Gantrez AN-119 0.2~0.5%；
1,2- hexylene glycol 0.5~0.8%；
Glycine betaine 0.2~0.5%；
Tapioca 0.1~0.2%；
Ammonium acryloyl taurate/VP copolymer 0.2~0.5%；
Carbomer 0.1~0.2%；
Pungent glycol 0.1~0.2%；
Cremophor RH40 0.2~0.8%；
Hydroxyethyl cellulose 0.01~0.02%；
Wild soybean seed extract 0.2~0.3%；
EDETATE SODIUM 0.2~0.3%；
Decoyl hydroximic acid 0.2~0.3%；
Tujue's rose caul-fat 0.2~0.3%；
Water surplus.
Application method:
After face cleaning skin toner, appropriate this product is taken uniformly to be applied to eye, face and neck skin, soft massage directly causes completely
It is absorbed.3-5 minutes smearings can be spaced once by being badly in need of improver, and morning and evening using effect is more preferably.
Storage method: it places at shady and cool drying, avoids direct sunlight.
Embodiment described above is typical embodiment or preferable embodiment of the invention, rather than is protected to the present invention
Protect the limitation of range.
Claims (9)
1. a kind of for improving the polypeptide Essence of skin quality, which is characterized in that component are as follows: propylene glycol, diglycerol, glycerol, fourth two
Alcohol, niacinamide, polyethylene glycol-8, PEG/PPG-17/6 copolymer, hamamelis water, glyceryl acrylate/acrylic acid copolymer
Object, Gantrez AN-119, palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3, dipeptides diaminobutyryl benzyl acyl
Amine diacetin, 1,2- hexylene glycol, glycine betaine, tapioca, ammonium acryloyl taurate/VP copolymer, carbomer, second
Acyl chitosamine, white willow bark extract, papain, Sodium Hyaluronate, pungent glycol, collagen, Cremophor RH40, hydroxyl
Ethyl cellulose, oligopeptides -1, Wild soybean seed extract, carnosine, EDETATE SODIUM, decoyl hydroximic acid, Tujue's rose caul-fat, water.
2. according to claim 1 for improving the polypeptide Essence of skin quality, which is characterized in that main component and content
Are as follows:
Niacinamide 2~3%；
Palmityl hexapeptide -14 1~1%；
Tripeptides -1, Argireline, pentapeptide -3 1~1%；
Dipeptides diaminobutyryl benzyl amide diacetin 0.6~1%；
Acetyl chitosamine 0.2~0.5%；
White willow bark extract 0.2~0.5%；
Papain 0.2~0.5%；
Sodium Hyaluronate 0.1~0.2%；
Collagen 0.1~0.2%；
Oligopeptides -1 0.03~0.05%；
Carnosine 0.01~0.02%.
3. according to claim 2 for improving the polypeptide Essence of skin quality, which is characterized in that main component and content
Are as follows:
Niacinamide 2%；
Palmityl hexapeptide -14 1%；
Tripeptides -1, Argireline, pentapeptide -3 1%；
Dipeptides diaminobutyryl benzyl amide diacetin 0.6%；
Acetyl chitosamine 0.2%；
White willow bark extract 0.2%；
Papain 0.2；
Sodium Hyaluronate 0.1%；
Collagen 0.1%；
Oligopeptides -1 0.03%；
Carnosine 0.01%.
4. according to claim 1 for improving the polypeptide Essence of skin quality, which is characterized in that remaining component and content
Are as follows:
Polyethylene glycol-8 0.2~0.5%；
PEG/PPG-17/6 copolymer 0.2~0.5%；
Hamamelis water 0.5~0.1%；
Glyceryl acrylate/acrylic copolymer 0.2~0.5%；
Gantrez AN-119 0.2~0.5%；
1,2- hexylene glycol 0.5~0.8%；
Glycine betaine 0.2~0.5%；
Tapioca 0.1~0.2%；
Ammonium acryloyl taurate/VP copolymer 0.2~0.5%；
Carbomer 0.1~0.2%；
Pungent glycol 0.1~0.2%；
Cremophor RH40 0.2~0.8%；
Hydroxyethyl cellulose 0.01~0.02%；
Wild soybean seed extract 0.2~0.3%；
EDETATE SODIUM 0.2~0.3%；
Decoyl hydroximic acid 0.2~0.3%；
Tujue's rose caul-fat 0.2~0.3%；
Water surplus.
5. according to claim 1 for improving the polypeptide Essence of skin quality, which is characterized in that remaining component and content
Are as follows:
Polyethylene glycol-8 0.2%；
PEG/PPG-17/6 copolymer 0.2%；
Hamamelis water 0.5%；
Glyceryl acrylate/acrylic copolymer 0.2%；
Gantrez AN-119 0.2%；
1,2- hexylene glycol 0.5%；
Glycine betaine 0.2%；
Tapioca 0.1%；
Ammonium acryloyl taurate/VP copolymer 0.2%；
Carbomer 0.1%；
Pungent glycol 0.1%；
Cremophor RH40 0.2%；
Hydroxyethyl cellulose 0.01%；
Wild soybean seed extract 0.2%；
EDETATE SODIUM 0.2%；
Decoyl hydroximic acid 0.2%；
Tujue's rose caul-fat 0.2%；
Water surplus.
6. according to claim 1 for improving the polypeptide Essence of skin quality, which is characterized in that the polypeptide Essence
Component and content are as follows:
Niacinamide 2%；Palmityl hexapeptide -14 1%；Tripeptides -1, Argireline, pentapeptide -3 1%；Dipeptides diaminobutyryl
Benzyl amide diacetin 0.6%；Acetyl chitosamine 0.2%；White willow bark extract 0.2%；Papain 0.2；It is transparent
Matter acid sodium 0.1%；Collagen 0.1%；Oligopeptides -1 0.03%；Carnosine 0.01%；Polyethylene glycol-8 0.2%；PEG/PPG-17/6
Copolymer 0.2%；Hamamelis water 0.5%；Glyceryl acrylate/acrylic copolymer 0.2%；Gantrez AN-119
0.2%；1,2- hexylene glycol 0.5%；Glycine betaine 0.2%；Tapioca 0.1%；Ammonium acryloyl taurate/VP copolymer
0.2%；Carbomer 0.1%；Pungent glycol 0.1%；Cremophor RH40 0.2%；Hydroxyethyl cellulose 0.01%；Wild soybean
Seed extract 0.2%；EDETATE SODIUM 0.2%；Decoyl hydroximic acid 0.2%；Tujue's rose caul-fat 0.2%；Water surplus.
7. described in claim 1 for improving the preparation method of the polypeptide Essence of skin quality, which is characterized in that including walking as follows
It is rapid: first by PEG/PPG-17/6 copolymer, glyceryl acrylate/acrylic copolymer, Gantrez AN-119, acryloyldimethyl
Taurine ammonium/VP copolymer after being added to the water immersion 30-60 minutes, stirs heating 80-90 degree；
Again by propylene glycol, water, diglycerol, glycerol, butanediol, niacinamide, polyethylene glycol-8, hamamelis water, 1,2- oneself two
Alcohol, glycine betaine, tapioca, carbomer, acetyl chitosamine, white willow bark extract, papain, pungent glycol, collagen,
Cremophor RH40, hydroxyethyl cellulose, Wild soybean seed extract, EDETATE SODIUM, decoyl hydroximic acid, Tujue rose
Oil, stirring heating 80-90 degree, is added above-mentioned system after stirring evenly；
Then pH value is adjusted between 5-6, palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3, dipeptides two is added
Aminobutyryl benzyl amide diacetin, oligopeptides -1, carnosine, Sodium Hyaluronate, stir evenly to get.
8. preparation method according to claim 7, which comprises the steps of: be first total to PEG/PPG-17/6
Polymers, Gantrez AN-119, ammonium acryloyl taurate/VP copolymer, adds glyceryl acrylate/acrylic copolymer
Enter and is impregnated in water after sixty minutes, 90 degree of stirring heating；
Again by propylene glycol, water, diglycerol, glycerol, butanediol, niacinamide, polyethylene glycol-8, hamamelis water, 1,2- oneself two
Alcohol, glycine betaine, tapioca, carbomer, acetyl chitosamine, white willow bark extract, papain, pungent glycol, collagen,
Cremophor RH40, hydroxyethyl cellulose, Wild soybean seed extract, EDETATE SODIUM, decoyl hydroximic acid, Tujue rose
Oil, 90 degree of stirring heating, is added above-mentioned system after stirring evenly；
Then pH value is adjusted between 5-6, palmityl hexapeptide -14, tripeptides -1, Argireline, pentapeptide -3, dipeptides two is added
Aminobutyryl benzyl amide diacetin, oligopeptides -1, carnosine, Sodium Hyaluronate, stir evenly to get.
9. the application of polypeptide Essence in skin care item described in claim 1 for improving skin quality.
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Application publication date: 20190712 |