CN112773760A

CN112773760A - Composition with multiple effects and multiple-effect essence

Info

Publication number: CN112773760A
Application number: CN202110119872.XA
Authority: CN
Inventors: 陈泽伦; 王帅
Original assignee: Guangzhou Heather Cosmetics Co ltd
Current assignee: Guangzhou Heather Cosmetics Co ltd
Priority date: 2021-01-28
Filing date: 2021-01-28
Publication date: 2021-05-11

Abstract

The invention relates to the field of cosmetics, and particularly discloses a composition with multiple effects and a multi-effect essence added with the composition. The composition with multiple effects comprises the following components in parts by weight: 1-5 parts of arginine/lysine polypeptide; 1-5 parts of hydroxypropyl tetrahydropyrane triol; 0.5-2 parts of ergothioneine/agaricus extract; 0.005-0.05 part of Liuwei Zhenbai. According to the composition with multiple effects, active polypeptide, natural plant extracts and other multiple effective components are compounded, so that the synergistic effect is achieved, the skin is nourished, the metabolism is promoted, and the permeation and absorption of the skin to the active components are improved; eliminating active oxygen free radicals in cells, prolonging cell life, inhibiting melanin formation and pigmentation caused by photodamage, eliminating mottle, and caring skin; meanwhile, the collagen synthesis and the repair of the dermis are promoted, the elasticity of skin fibrous tissues is improved, the skin is smooth and compact, the skin texture is refined, the moisture content of the skin is improved, and the glossiness of the skin is improved.

Description

Composition with multiple effects and multiple-effect essence

Technical Field

The invention relates to the field of cosmetics, in particular to a composition with multiple effects of whitening, removing freckles, resisting aging and the like and a multi-effect essence added with the composition.

Background

With the pace of life of people becoming faster, the working pressure and the living pressure are increasing day by day, and the problems of environmental pollution and food are generated, so that the skin problems of people are gradually highlighted. The skin is an important organ for maintaining the life health of people, and the main reason of skin wrinkles is skin dehydration and sebum peroxidation. With the improvement of living standard of people and the attention on skin health, the problem of how to reduce the generation of wrinkles and recover youthful skin color is a great concern of people.

From the academic research of life science, biological technology, apoptosis aging and the like, the skin aging is the result of a comprehensive factor. Skin aging is mainly in the form of natural aging (i.e., intrinsic aging) and photoaging (i.e., extrinsic aging), which is mainly caused by body genetic factors, is limited to the whole body, and is apparently characterized by wrinkles and sagging, and pigmentation, etc. Photoaging is mainly skin aging caused by accumulation of ultraviolet damage, is a result of combined action of natural aging and ultraviolet irradiation, is limited to exposed parts of skin, and is mainly characterized by rough and lusterless skin, deepening walking stability, deepening pigmentation, worsening skin microcirculation, deformation of elastic tissues, reduction of the skin expression of scavenging capacity, synthesis capacity and immunity of collagen and elastin, thinning of dermis, easy occurrence of allergic inflammation and the like.

At present, the whitening and anti-wrinkle products are various, most of the whitening and anti-wrinkle products are chemical synthesis agents, even a large amount of chemical synthesis substances can be contained, although the whitening and anti-wrinkle effects can be achieved in a short period, in a long term, the problems of the skin cannot be solved, the burden of the skin is increased, some anaphylactic reactions are caused, and the skin is damaged. For the freckle removing product, the traditional Chinese medicine extract is used as an additive, but most of the effects of the traditional Chinese medicine extract are to inhibit the formation of melanin in skin, and the melanin in the skin cannot be effectively decomposed to remove freckles in the true sense. In recent years, laser spot removal, photon skin tendering and the like are relatively many technologies, and although the means can achieve an instant effect in a short time, the effect is difficult to maintain, and the treatment cost is high, so that the method is not suitable for popularization and use.

The existing product does not have a skin care product which integrates the effects of whitening, removing freckles and resisting wrinkles, does not cause any damage to skin and really solves the fundamental problem of skin of people.

Disclosure of Invention

The present invention is directed to overcoming at least one of the disadvantages of the prior art, and to provide a multi-effect composition having multiple effects of whitening, removing freckles, resisting aging, etc., without any damage to the skin, and a multi-effect essence containing the multi-effect composition.

The invention adopts the technical scheme that a composition with multiple effects comprises the following components in parts by weight: 1-5 parts of arginine/lysine polypeptide; 1-5 parts of hydroxypropyl tetrahydropyrane triol; 0.5-2 parts of ergothioneine/agaricus extract; 0.005-0.05 part of Liuwei Zhenbai.

The arginine/lysine polypeptide is a short peptide with the characteristics of highly folded structure, strong osmotic energy, high stability, strong selectivity, strong activity and the like, and provides a strong relaxation effect on muscles of skin controlled expression, thereby fundamentally achieving the purpose of smoothing wrinkles.

The hydroxypropyl tetrahydropyrane triol is one of xylose derivatives, can promote the synthesis of glycosaminoglycans (GAGs) and proteoglycan in skin, and can promote the synthesis of collagen VII and collagen IV, thereby strengthening the connection between epidermis and dermis, relieving skin aging, playing the roles of promoting the repair of dermis, improving the moisture content of skin, improving the elasticity of skin and increasing the skin tightness, and leading the skin to be more exquisite and glossy.

Ergothioneine/matsutake extracts are water soluble liquids: wherein, the ergothioneine is naturally present in human body, is transported into cell nucleus mitochondria through transporter OCTN-1 in keratinocyte and fibroblast, directly eliminates active oxygen free radical, plays the role of antioxidation and cell protection, and prolongs the cell life. ergothioneine/Armillaria matsutake extract containing high concentration of ergothioneine (0.01% -0.03%) as effective active ingredient provides ergothioneine as effective active ingredient for skin, protects cell DNA from UV ultraviolet injury, and has effects of scavenging oxygen free radical, reducing pigmentation and skin roughness caused by UV irradiation, smoothing skin, refining skin texture, and improving skin luster.

Six medicinal herbs including bulrush extract, licorice root extract, angelica root extract, red sage root extract, dogwood fruit extract and wolfberry root extract are combined in a synergistic way, so that the skin shows uniform skin color from inside to outside. The reed and liquorice extracts have the functions of clearing away heat and toxic materials, relieving inflammation and good antioxidant activity; the angelica and ginseng extracts have the effects of promoting blood circulation to remove blood stasis, improving skin microcirculation, promoting metabolism and properly inhibiting melanin generation on the premise of ensuring safety (cell viability); the dogwood extract has the effects of nourishing yin, promoting the production of body fluid, replenishing water, moisturizing, improving the brightness and glossiness of skin and dispersing and gathering melanin; the medlar root extract has the functions of tonifying, nourishing cells and improving the skin state.

According to the invention, arginine/lysine polypeptide, hydroxypropyl tetrahydropyrane triol, ergothioneine/agaricus extract and six ingredient Zhen Bai are compounded, and the components are synergistic, so that on one hand, the skin aging is slowed down, the firmness of the skin is increased and wrinkles are eliminated through multiple ways; on the other hand, the damage of light to the skin is reduced by eliminating active oxygen free radicals, and meanwhile, the herbal essence is adopted to improve skin microcirculation, reduce the dull and bright skin color of the skin and enable the skin to be healthy and glossy.

As a preferable technical scheme, the composition also comprises 0.3-0.7 part of tetrahydro-methyl pyrimidine carboxylic acid; 0.5-1.5 parts of secondary cracking yeast fermentation product filtrate; 0.5-1 part of gentian extract.

The tetrahydro-methyl pyrimidine carboxylic acid is derived from a microorganism in Wadi EI Natrun salt lake in Egypt desert area, is an amino acid derivative, has strong anti-compression protection function, can restrict surrounding water molecules to form a complex, and wraps around cells, enzymes, proteins and other organic molecules to form a protective shell with the functions of protection, nourishment and stable hydration, so that the skin can be protected from being damaged by infrared radiation.

The secondary fission yeast fermentation product filtrate is a complex of metabolites and cell fragments obtained by culturing, inactivating and decomposing bifidobacterium, contains abundant active micromolecules such as vitamins, minerals, amino acids, polysaccharides, polypeptides and the like, and is high-quality yeast essence only used for skin care. The product is rich in nutrients, and has skin nourishing effect. When the skin care product is applied to skin care products, the skin care product can strengthen skin metabolism, promote cell proliferation, tighten skin, reduce fine wrinkles and has a good wrinkle removing function.

The Gentiana scabra Bunge extract is extracted from dried root or tuber of Gentianaceae plant, and can enhance antiinflammatory and antibacterial effects of the product.

As a preferable technical scheme, the composition also comprises 0.2-1 part of lactobacillus/soybean milk fermentation product filtrate; 0.005-0.02 part of ganoderma lucidum extract.

The lactobacillus/soybean milk fermentation product filtrate is a black soybean milk filtrate obtained by fermenting 16 35 strains of lactobacillus, is rich in various vitamins, proteins and active ingredients, and has the effects of reducing allergy, relieving, moisturizing, repairing and whitening; the ganoderma lucidum extract has obvious anti-inflammatory effect, can obviously improve the free radical scavenging capability of blood, particularly can resist obviously harmful hydroxyl free radicals, realizes the anti-cell aging effect by scavenging the free radicals and inhibits the secretion of tyrosinase.

According to the scheme, the anti-inflammatory and soothing functional components are added into the composition, so that the resistance of the skin to external stimulation is improved in multiple ways, the skin pressure is reduced, and the skin quality is improved.

As a preferable technical scheme, the composition also comprises 0.5-3 parts of seawater. The seawater adopted by the scheme is rich in various mineral elements, has good conductivity, ion exchange and osmosis, is beneficial to relieving fatigue and reducing wrinkles, can provide an instant cooling effect, and has an anti-inflammatory effect. Meanwhile, the seawater is added into the composition, so that the permeation effect of each component in the composition can be improved, and the absorption of skin to the product can be improved.

The multi-effect essence comprises 2.5-20 parts of the multi-effect composition, and further comprises the following components in parts by weight:

as a preferred technical scheme, the skin conditioner comprises 0.5-2 parts of alpha-arbutin; 2-4 parts of nicotinamide; 0.01-0.05 parts of phellodendron amurense bark extract; 0.001-0.1 part of glabridin.

As a preferable technical scheme, the skin conditioner also comprises one or more of retinol palmitate, red sage root oil, yeast schizophragma bifida fermentation product lysate, rosa damascena flower water, centella asiatica extract and ascorbic acid. Preferably, the addition amount of each component is 0.0001-0.01 part.

As a preferable technical scheme, the humectant adopts one or more of dipropylene glycol, erythritol, 1, 2-hexanediol, hydrolyzed sodium hyaluronate and PEG/PPG-17/6 copolymer; the emollient is glycerol tri (ethyl hexanoate).

As a preferable technical scheme, the thickening agent is a combination of acryloyl dimethyl ammonium taurate/behenyl polyether-25 methacrylate cross-linked polymer and polyacrylic dimethyl ammonium taurate, and the weight part ratio of the thickening agent is 1: (0.5-2). Further, the weight part ratio of the acryloyl dimethyl ammonium taurate/behenyl polyether-25 methacrylate cross-linked polymer to the polyacrylic dimethyl ammonium taurate is 1: (0.75-1.35). The thickener combination provided by the scheme can synergistically improve the viscosity of a system, has a high-efficiency thickening effect, does not influence the use feeling of a product, and still has excellent thickening capability in a system containing electrolyte.

As a preferred technical scheme, the emulsifier is PEG-60 hydrogenated castor oil; the solubilizer is PEG-40 hydrogenated castor oil.

As a preferable technical scheme, the antioxidant adopts one or more of tocopherol (vitamin E) and p-hydroxyacetophenone.

Compared with the prior art, the invention has the beneficial effects that:

(1) the invention provides a composition with multiple effects, which is prepared by compounding multiple effective components such as active polypeptide, natural plant extract and the like, has synergistic effect, nourishes skin, promotes metabolism, and promotes the skin to permeate and absorb the active components; eliminating active oxygen free radicals in cells, prolonging cell life, inhibiting melanin formation and pigmentation caused by photodamage, eliminating mottle, and caring skin; meanwhile, the collagen synthesis and the repair of the dermis are promoted, the elasticity of skin fibrous tissues is improved, the skin is smooth and compact, the skin texture is refined, the moisture content of the skin is improved, and the glossiness of the skin is improved.

(2) The essence provided by the invention has good permeability and is easy to absorb, and can inhibit the generation of oxygen radicals, block the formation of melanin stimulated by ultraviolet rays, and radically block the formation of spots, so that color spots are thoroughly removed, the skin is whitened and tender, meanwhile, the cell regeneration is promoted, the wrinkle regeneration is inhibited, the skin aging is delayed, the skin is bright and compact, and the skin is moist, fine and glossy.

Detailed Description

The technical solution of the present invention is further explained by the following embodiments. It should be understood by those skilled in the art that the examples are only for the understanding of the present invention and should not be construed as the specific limitations of the present invention. For process parameters or conditions not specifically mentioned, it can be carried out with reference to conventional techniques.

The starting materials used in the present invention are commercially available.

Arginine/lysine polypeptides are supplied by Zhejiang surge peptide biology, Inc.; hydroxypropyl tetrahydropyran triol is available from Guangzhou Junlang Biotechnology Co., Ltd under the trade name Pro-Xylane Lightening; ergothioneine/Armillaria matsutake extracts were provided by Huaxi Biotech Co., Ltd; liuwei Zhen Bai from Guangzhou vast Sen Fine chemical Co., Ltd, cat # NW-01-1069; tetrahydromethylpyrimidine carboxylic acid is available from Kyoho, Guangzhou under the trade name Ectoin, from Germany; the secondary split yeast fermentation product Filtrate is provided by Dongguan Hua industrial creation and biological science and technology limited company, and is sold under the trade name of Rejuvactor Filter; the radix Gentianae extract is provided by Shanghai Gayu Biotech limited, and has product number of JY 1004-2.5; the lactobacillus/soybean milk fermentation product filtrate was supplied by xiantang (guangzhou) trade limited under the trade name of oxitenmin, produced in japan; ganoderma extract is provided by Huzhou Zhenlu biological products, Inc.; the radix Salviae Miltiorrhizae oil is provided by vast forest Biotech limited of Beijing Oriental; cortex Phellodendri bark extract is provided by the Korean Ruidi-an (RADIANT) company; glabridin is provided by Gansu pan-plant pharmaceuticals, Inc.; the lysate of the fermentation product of the yeast schizosaccharomyces boulardii is provided by Dongguan engineering and Biotech Co., Ltd, and is sold under the trade name of Rejuvactor NP; rosa damascena flower water is provided by biological science and technology Limited, Huilan, Guangzhou; centella asiatica extract is sold under the trade name

WS; the trade name of the acryloyl dimethyl ammonium taurate/behenyl polyether-25 methacrylate cross-linked polymer is

BLV。

Example 1

This example provides a composition with multiple effects, consisting essentially of: arginine/lysine polypeptide 2 g; 3g of hydroxypropyl tetrahydropyrane triol; ergothioneine/Armillaria matsutake extract 0.5 g; liu Wei Zhen Bai 0.01 g.

Example 2

This example provides a composition with multiple effects, consisting essentially of: 5g of arginine/lysine polypeptide; 2g of hydroxypropyl tetrahydropyrane triol; 1.5g ergothioneine/Armillaria matsutake extract; 0.04g of Liuwei Zhenbai and 0.5g of tetrahydro-methyl pyrimidine carboxylic acid; 1g of secondary split yeast fermentation product filtrate; radix Gentianae extract 0.5 g.

Example 3

This example provides a composition with multiple effects, consisting essentially of: 1g of arginine/lysine polypeptide; 1g of hydroxypropyl tetrahydropyrane triol; 1g ergothioneine/Armillaria matsutake extract; 0.02g of Liuwei Zhenbai and 0.4g of tetrahydro-methyl pyrimidine carboxylic acid; 1.5g of secondary split yeast fermentation product filtrate; 0.8g of gentian extract and 0.5g of lactobacillus/soybean milk fermentation product filtrate; ganoderma extract 0.01 g.

Example 4

This example provides a composition with multiple effects, consisting essentially of: 3.5g of arginine/lysine polypeptide; 5g of hydroxypropyl tetrahydropyrane triol; ergothioneine/Armillaria matsutake extract 2 g; 0.05g of Liuwei Zhenbai and 0.3g of tetrahydro-methyl pyrimidine carboxylic acid; 0.8g of secondary split yeast fermentation product filtrate; 0.5g of gentian extract and 0.7g of lactobacillus/soybean milk fermentation product filtrate; 0.02g of lucid ganoderma extract and 2.5g of seawater.

Example 5

The embodiment provides a multi-effect essence which mainly comprises the following components: 5.51g of the multiple effect composition provided in example 1, 3.35g of skin conditioner, 7.03g of humectant, 0.1g of emollient, 0.3g of thickener, 0.1g of emulsifier, 0.02g of chelating agent (disodium EDTA), 0.03g of solubilizer, 0.3g of antioxidant, and water to 100 g.

The skin conditioner specifically comprises the following components: 1g of alpha-arbutin; 2g of nicotinamide; 0.03g of phellodendron amurense bark extract; glabridin 0.05 g. The humectant specifically comprises the following components: 4g of dipropylene glycol, 1.5g of erythritol, 0.5g of 1, 2-hexanediol, 0.03g of hydrolyzed sodium hyaluronate and 1g of PEG/PPG-17/6 copolymer. The emollient is glycerol tri (ethyl hexanoate). The thickening agent comprises 0.2g of acryloyl dimethyl ammonium taurate/behenyl alcohol polyether-25 methacrylate cross-linked polymer and 0.1g of polyacryl dimethyl ammonium taurate. The emulsifier is PEG-60 hydrogenated castor oil. The solubilizer is PEG-40 hydrogenated castor oil. The antioxidant is specifically tocopherol (vitamin E)0.05g and p-hydroxyacetophenone 0.25 g.

Example 6

The embodiment provides a multi-effect essence which mainly comprises the following components: 10.54g of the multiple effect composition provided in example 2, 3.5746g of skin conditioner, 15.1g of humectant, 0.3g of emollient, 0.7g of thickener, 0.15g of emulsifier, 0.03g of chelating agent (disodium EDTA), 0.05g of solubilizer, 0.51g of antioxidant, 0.001g of fragrance, and water to 100 g.

The skin conditioner specifically comprises the following components: 0.5g of alpha-arbutin; 3g of nicotinamide; 0.05g of phellodendron amurense bark extract; glabridin 0.008 g; 0.001g of retinol palmitate; 0.01g of red sange nourishing oil; 0.005g of a split yeast fermentation lysate; 0.01g of rosa damascena flower water; centella asiatica extract 0.0005 g; ascorbic acid 0.0001 g. The humectant specifically comprises the following components: 8g of dipropylene glycol, 4g of erythritol, 1g of 1, 2-hexanediol, 0.1g of hydrolyzed sodium hyaluronate and 2g of PEG/PPG-17/6 copolymer. The emollient is glycerol tri (ethyl hexanoate). The thickening agent comprises 0.4g of acryloyl dimethyl ammonium taurate/behenyl alcohol polyether-25 methacrylate cross-linked polymer and 0.3g of polyacryl dimethyl ammonium taurate. The emulsifier is PEG-60 hydrogenated castor oil. The solubilizer is PEG-40 hydrogenated castor oil. The antioxidant is specifically tocopherol (vitamin E)0.01g and p-hydroxyacetophenone 0.5 g. The aromatic agent is vegetarian fanghua oil.

Example 7

The embodiment provides a multi-effect essence which mainly comprises the following components: 6.23g of the multiple effect composition provided in example 3, 6.1461g of skin conditioner, 10.05g of moisturizer, 0.1g of emollient, 0.8g of thickener, 0.2g of emulsifier, 0.05g of chelating agent (disodium EDTA), 0.06g of solubilizer, 0.75g of antioxidant, 0.005g of fragrance, and water to 100 g.

The skin conditioner specifically comprises the following components: 2g of alpha-arbutin; 4g of nicotinamide; 0.01g of phellodendron amurense bark extract; glabridin 0.1 g; 0.01g of retinol palmitate; 0.01g of red sange nourishing oil; 0.01g of a split yeast fermentation lysate; 0.001g of rosa damascena flower water; centella asiatica extract 0.005 g; ascorbic acid 0.0001 g. The humectant specifically comprises the following components: 5g of dipropylene glycol, 3g of erythritol, 0.5g of 1, 2-hexanediol, 0.05g of hydrolyzed sodium hyaluronate and 1.5g of PEG/PPG-17/6 copolymer. The emollient is glycerol tri (ethyl hexanoate). The thickening agent comprises 0.4g of acryloyl dimethyl ammonium taurate/behenyl alcohol polyether-25 methacrylate cross-linked polymer and 0.4g of polyacryl dimethyl ammonium taurate. The emulsifier is PEG-60 hydrogenated castor oil. The solubilizer is PEG-40 hydrogenated castor oil. The antioxidant is specifically tocopherol (vitamin E)0.05g and p-hydroxyacetophenone 0.7 g. The aromatic agent is vegetarian fanghua oil.

Example 8

The embodiment provides a multi-effect essence which mainly comprises the following components: 15.37g of the multiple effect composition provided in example 2, 5.2394g of skin conditioner, 20.2g of moisturizer, 0.5g of emollient, 0.5g of thickener, 0.1g of emulsifier, 0.01g of chelating agent (disodium EDTA), 0.03g of solubilizer, 0.25g of antioxidant, 0.01g of fragrance, and water to 100 g.

The skin conditioner specifically comprises the following components: 1.2g of alpha-arbutin; 4g of nicotinamide; 0.02g of phellodendron amurense bark extract; glabridin 0.01 g; 0.0001g of retinol palmitate; 0.006g of red sang nourishing oil; 0.0001g of schizosaccharomyces cerevisiae fermentation product lysate; 0.003g of rosa damascena flower water; centella asiatica extract 0.0001 g; ascorbic acid 0.0001 g. The humectant specifically comprises the following components: the gel comprises 12g of dipropylene glycol, 4g of erythritol, 2g of 1, 2-hexanediol, 0.2g of hydrolyzed sodium hyaluronate and 2g of PEG/PPG-17/6 copolymer. The emollient is glycerol tri (ethyl hexanoate). The thickening agent comprises 0.2g of acryloyl dimethyl ammonium taurate/behenyl alcohol polyether-25 methacrylate cross-linked polymer and 0.3g of polyacryl dimethyl ammonium taurate. The emulsifier is PEG-60 hydrogenated castor oil. The solubilizer is PEG-40 hydrogenated castor oil. The antioxidant is specifically tocopherol (vitamin E)0.05g and p-hydroxyacetophenone 0.2 g. The aromatic agent is vegetarian fanghua oil.

Comparative example 1

The difference from example 1 is that the amount of arginine/lysine polypeptide added is 0.5 g.

Comparative example 2

The difference from example 1 is that the amount of hydroxypropyl tetrahydropyrane triol added was 0.5 g.

Comparative example 3

The difference from example 1 is that ergothioneine/matsutake extract was added in an amount of 0.2 g.

Comparative example 4

The difference from example 1 is that the amount of Liuwei Zhenbai added was 0.005 g.

Test examples

Test 1: skin brightness ITA ° value test

The change in skin color can be measured using a skin complexion measuring instrument. The currently widely adopted measuring method for quantifying skin color is to measure the change of skin color by a colorimetric system (Lab colorimetric system) specified by the International Commission on illumination (CIE), and the method has accurate quantification, can reflect the multidimensional change of a skin color space, and ensures that the skin color is quantified more reliably. The test index is the skin individual type angle ITA ° (the greater the value of ITA °, the brighter the skin). Therefore, the whitening effect of the cosmetic can be judged by measuring the skin chromaticity.

△ITA°＝T_n-T₀(ii) a In the formula T_nThe time-varying value of the tested area; t is₀Is the initial value of the tested area.

An experimental instrument: multifunctional skin test system (MPA 6, CK, germany); skin color difference test probe (CL400, CK, germany).

The experimental method comprises the following steps: screening 60 adults with dull facial skin color, randomly dividing the adults into 12 groups, taking 5 adults in each group as testers, carrying out melanin and color difference data acquisition analysis and test on the facial skin before trying out samples, and taking the data as a skin background value. The sample was used once in the morning and at night for 4 weeks. Data acquisition was performed with a skin tone difference test probe and a multifunctional skin test system (CL400 and MPA 6, germany CK) before and 4 weeks of use, respectively, with the test site being the left cheek bone. Evaluating the change of the skin brightness ITA DEG value before and after the cosmetic is used by the subject, wherein the larger the ITA DEG value is, the brighter the skin is, and conversely, the darker the skin is, thereby determining the effect of the cosmetic on improving the skin darkness. The test results are shown in Table 1.

Experimental samples: the multi-effect essence of examples 1 to 8 and comparative examples 1 to 4 (the essence is prepared by adding the compositions of examples 1 to 4 and comparative examples 1 to 4 to a substrate, wherein the addition amount of the compositions is 10% of the total mass of the cosmetic).

TABLE 1 statistical results of ITA DEG values of skin brightness before and after use of the product

As can be seen from the experimental results in table 1, the skin brightness ITA ° value of the essence prepared by using the compositions of the examples of the present invention is significantly increased compared to the comparative examples, which shows that the compositions provided by the examples of the present invention have the effect of improving skin brightness, and can improve the problems of skin darkness and skin spots.

And (3) testing 2: free radical scavenging ability test

This experiment evaluates the radical scavenging properties of the compositions of the present invention by measuring the rate of radical scavenging of DPPH by the compositions. DPPH free radical is a stable nitrogen center organic free radical, strong absorption is achieved at 517nm, an ethanol solution of DPPH is purple, when the DPPH free radical scavenger is encountered, single electrons of DPPH are paired to enable the color of the solution to become light, the fading degree of the DPPH free radical is in quantitative relation with the quantity of the received electrons, therefore, a spectrophotometer can be used for carrying out quantitative analysis to detect the condition of scavenging the free radicals, and the higher the scavenging rate is, the stronger the oxidation resistance and the anti-aging capacity of the DPPH free radical is.

(1) Test samples: the compositions prepared in examples 1 to 4 and comparative examples 1 to 4 were diluted with deionized water to give a test solution having a mass fraction of 1%.

(2) The test method comprises the following steps: taking 4mL of DPPH-absolute ethanol solution with the concentration of 0.1mmol/L into a container, adding 2mL of test sample, uniformly mixing, keeping out of the sun for 30min at room temperature, measuring the absorbance at the wavelength of 517nm, and recording the absorbance as A1; taking 4mL of absolute ethyl alcohol solution and 2mL of test sample solution, and recording the absorbance value A2 under the same condition; the absorbance values of 4mL of DPPH-absolute ethanol solution and 2mL of absolute ethanol solution measured under the same conditions as above were recorded as A3. DPPH radical clearance was calculated as follows: DPPH radical clearance (%) [1- (a1-a2)/A3] × 100%, average of three measurements. The test results are shown in table 2.

TABLE 2 DPPH radical scavenging ability test results

Sample (I)	DPPH radical scavenging ratio (%)
		Example 1	76.4
Example 2	78.8
		Example 3	81.2
Example 4	84.5
		Comparative example 1	71.9
Comparative example 2	72.3
		Comparative example 3	53.6
Comparative example 4	72.0

The experimental results in table 2 show that the composition of the present invention has a strong scavenging ability for DPPH radicals and a better scavenging effect than the comparative examples, which indicates that the composition of the present invention synergistically enhances the scavenging ability of the composition for radicals, increases the antioxidant property, and achieves the anti-aging effect.

And (3) testing: skin elasticity test

1) Test samples: the multi-effect essence of examples 1 to 8 and comparative examples 1 to 4 (the essence is prepared by adding the compositions of examples 1 to 4 and comparative examples 1 to 4 to a substrate, wherein the addition amount of the compositions is 10% of the total mass of the cosmetic).

2) The test method comprises the following steps: 60 volunteers with obvious wrinkles on the face of 30-50 years old are selected and randomly divided into 12 groups of 5 persons. The application method comprises the steps of using the sample once in the morning and at the evening after cleaning the face every day. The experimental period is 4 weeks, data acquisition is carried out by a skin elasticity meter MPA580 before use and after use for 4 weeks respectively, the test part is the forehead, the probe repeatedly measures for 3 times in the same tested area during measurement, and an average value is taken. The test parameter is R2 (the ratio of the springback amount Ua of the skin without negative pressure to the maximum stretch amount Uf with negative pressure), the closer R2 is to 1, the better the elasticity of the skin, and the average change value of R2 is from the 4 th cycle R2 value to the 0 th cycle R2 value. The test results are shown in table 3.

Table 3 skin elasticity test results

As can be seen from the experimental results in table 3, the change of the skin elasticity R2 value is large after 4 weeks using the essence prepared in the examples, which indicates that both the multi-effect composition and the essence of the present invention have good anti-wrinkle effects. The use of the comparative example, which has a smaller increase in facial skin elasticity R2, demonstrates that the synergistic benefits of the ingredients in the skin care compositions of the present invention are better at achieving anti-aging benefits.

It should be understood that the above-mentioned embodiments of the present invention are only examples for clearly illustrating the technical solutions of the present invention, and are not intended to limit the specific embodiments of the present invention. Any modification, equivalent replacement, and improvement made within the spirit and principle of the present invention claims should be included in the protection scope of the present invention claims.

Claims

1. The composition with multiple effects is characterized by comprising the following components in parts by weight:

1-5 parts of arginine/lysine polypeptide;

1-5 parts of hydroxypropyl tetrahydropyrane triol;

0.5-2 parts of ergothioneine/agaricus extract;

0.005-0.05 part of Liuwei Zhenbai.

2. The composition with multiple effects according to claim 1, further comprising 0.3-0.7 parts of tetrahydro-methyl pyrimidine carboxylic acid; 0.5-1.5 parts of secondary cracking yeast fermentation product filtrate; 0.5-1 part of gentian extract.

3. The composition with multiple effects according to claim 1, further comprising 0.2-1 part of lactobacillus/soybean milk fermentation product filtrate; 0.005-0.02 part of ganoderma lucidum extract.

4. The composition with multiple effects according to claim 1, further comprising 0.5-3 parts of seawater.

5. The multi-effect essence is characterized by comprising 2.5-20 parts of the multi-effect composition as defined in any one of claims 1-4, and further comprising the following components in parts by weight:

2.5-6.5 parts of a skin conditioner;

3-20 parts of a humectant;

0.1-0.5 parts of an emollient;

0.2-0.8 part of thickening agent;

0.05-0.2 part of an emulsifier;

0.005-0.05 part of a chelating agent;

0.01-0.06 parts of solubilizer;

0.2-0.8 part of antioxidant;

0-0.01 part of an aromatic;

water was added to 100 parts.

6. The multi-effect essence according to claim 5, wherein the skin conditioner comprises 0.5-2 parts of alpha-arbutin; 2-4 parts of nicotinamide; 0.01-0.05 parts of phellodendron amurense bark extract; 0.001-0.1 part of glabridin.

7. The multi-effect essence of claim 6, wherein the skin conditioner further comprises one or more of retinol palmitate, crepidote, yeast lysate of bifida ferment, Rosa damascena water, centella asiatica extract, ascorbic acid.

8. The multi-effect essence according to any one of claims 5 to 7, wherein the humectant is one or a combination of dipropylene glycol, erythritol, 1, 2-hexanediol, hydrolyzed sodium hyaluronate, and PEG/PPG-17/6 copolymer; the emollient is glycerol tri (ethyl hexanoate).

9. The multi-effect essence according to any one of claims 5 to 7, wherein the thickener is a combination of an ammonium acryloyl dimethyl taurate/behenyl polyether-25 methacrylate cross-linked polymer and an ammonium polyacryl dimethyl taurate, and the ratio of the thickener to the ammonium acryloyl dimethyl taurate is 1: (0.5-2).

10. The multi-effect essence according to any one of claims 5 to 7, wherein the emulsifier is PEG-60 hydrogenated castor oil; the solubilizer is PEG-40 hydrogenated castor oil.