CN110448511B

CN110448511B - Anti-makeup and anti-blue-light skin conditioner, skin cream and preparation method thereof

Info

Publication number: CN110448511B
Application number: CN201910844470.9A
Authority: CN
Inventors: 龚德明; 范玉菡
Original assignee: Guangzhou Biotechnology Co ltd
Current assignee: Guangzhou Biotechnology Co ltd
Priority date: 2019-09-06
Filing date: 2019-09-06
Publication date: 2022-09-02
Anticipated expiration: 2039-09-06
Also published as: CN110448511A

Abstract

The invention relates to a skin conditioner and a skin cream for preventing makeup loss and resisting blue light and a preparation method thereof. The invention also relates to a makeup-preventing and blue-light-resisting skin-care cream, which comprises the skin conditioner, the humectant, the emollient, the emulsifier and water in parts by weight. The skin cream has remarkable effects of balancing skin oil secretion and preventing makeup removal; has remarkable effects of diminishing inflammation, resisting allergy and relieving skin; the whitening and brightness of the skin can be remarkably improved, and the skin color can be modified; meanwhile, the blue light-shielding material has the effects of shielding blue light, resisting light invasion and repairing light damage.

Description

Anti-makeup and anti-blue-light skin conditioner, skin-beautifying cream and preparation method thereof

Technical Field

The invention belongs to the technical field of cosmetics, and relates to a skin conditioner, a skin cream and a preparation method thereof, in particular to a skin conditioner, a skin cream and a preparation method thereof, wherein the skin conditioner and the skin cream are capable of preventing makeup loss and resisting blue light.

Background

The skin cream is convenient to carry, and is the most different from the traditional skin care products in that the skin cream is a combination of the skin care products and the color cosmetics, not only has the functions of moistening skin, moisturizing and moisturizing of the traditional skin care products, but also has the functions of whitening, brightening and concealing blemishes of the color cosmetics, and also has a certain physical sunscreen function. In the fast-paced work and life, the facial cream can be applied only a little after best basic care is carried out, and the facial cream can be directly washed clean by facial cleanser without makeup removal at night, so that the facial cream is popular.

CN107468586A discloses a water-yielding moisturizing essence face cream and a preparation method thereof. The water-yielding moisturizing essence face cream is prepared from the following raw materials in percentage by weight: 3-7% of emulsifier, 1-5% of thickening elastomer, 0.5-3.5% of silicone oil, 5-10% of grease, 5-8% of titanium dioxide, 1-5% of oil phase thickener, 15-25% of humectant, 0.9-1.5% of pH regulator, 0.1-0.8% of preservative, 1-3% of active ingredient and the balance of deionized water. The face cream disclosed by the invention has the advantages of good handfeel, freshness, moisture and good ductility, and can naturally cover blemishes and whiten, and has silky smooth feeling and moist joyful feeling after water is discharged when the face cream is applied. The invention can be applied to naturally whiten skin and make the skin feel wet, and has the inherent whitening and moisturizing effects.

CN106474040A discloses a pearl essence cream and a preparation method thereof, the pearl essence cream is prepared from isononyl isononanoate, pentaerythritol tetraester, boron nitride, pearl powder, an emulsifier, a thickening agent, glycerol, aluminum starch octenyl succinate, bismuth oxychloride, alpinia katsumadai seed extract, pearl extract, icelandia lichen extract, cyperus rotundus extract, hydroxyproline silanol, a preservative and deionized water. In the formula of the face cream, the pearl powder, the pearl extract, the alpinia katsumadai extract and the Iceland moss extract have the effects of complementation and synergy in the aspects of conditioning and brightening skin. The preparation process of the pearl essence facial cream adopts a cold preparation method, is economical and environment-friendly, and is simple to operate.

CN106265475A discloses a water-resistant makeup-free facial cream and a preparation method thereof, which consists of grease, an emulsifier, a rheology regulator, a humectant, titanium dioxide, active ingredients and deionized water thereof. Compared with the prior art, the skin cream prepared by the invention has good water resistance, long make-up holding time, natural concealer and whitening, and the proper matching of the grease and the powder improves the phenomena of powder floating and easy mud rubbing of market products after use. The product has good spreading type, good moistening effect, and can be cleaned with common facial cleanser, so as to achieve the purpose of no need of removing makeup.

However, the skin-whitening cream in the prior art often has the following disadvantages: the product has no or poor sweat-proof effect, and can be applied to skin for less than 2 hr to restore skin color, and lose functions of skin decoration and beautifying; the formula technology is laggard and traditional, still stays on the basis of moisture retention and whitening in the past, cannot follow the living habits and requirements of consumers which are changed rapidly, and cannot be used for the blue light of long-term dangerous skin such as mobile phones, display screens and the like. Therefore, it is very significant to develop a skin-care cream which can prevent makeup loss, resist blue light, modify skin color, preserve moisture and resist aging.

Disclosure of Invention

Aiming at the defects of the prior art, the invention aims to provide a skin conditioner, a skin cream and preparation methods thereof, and particularly provides a makeup-removing and blue-light-resistant skin conditioner, a skin cream and preparation methods thereof.

In order to achieve the purpose, the invention adopts the following technical scheme:

in one aspect, the invention provides a make-up reduction and blue light resistance skin conditioner comprising a buddleja officinalis extract, a sophora flavescens root extract, a glycyrrhiza inflate root extract, a scutellaria baicalensis root extract, an angelica sinensis extract, a bletilla striata extract, a lysimachia christinae extract and a salvia officinalis extract.

The sophora flavescens root extract contains active ingredients such as matrine, oxymatrine, hydroxymatrine and the like, and can balance oil secretion, dredge and astringe pores, remove toxin impurities in skin, relieve skin itch, promote growth and repair of damaged vascular nerve cells, recover activity of subcutaneous capillary cells and promote skin tightness and smoothness. The collagen component in the glycyrrhiza inflata root extract can enable the skin to be firmer, and meanwhile, the anti-aging component in the glycyrrhiza inflata root extract can obviously resist the deposition of melanin, so that the skin whitening effect is achieved.

The radix scutellariae extract has obvious anti-inflammation and anti-allergy effects and can relieve skin allergy probability, and the zinc baicalin and the copper baicalin contained in the radix scutellariae extract have obvious scavenging effect on superoxide radical, protect skin cells from over oxidation of the superoxide radical and inhibit the generation of melanin. The angelica sinensis extract can expand capillary vessels and accelerate blood circulation, is rich in trace elements, can nourish skin and prevent skin from drying, and has remarkable effects of resisting oxidation and removing free radicals.

The bletilla striata extract contains a large amount of volatile oil, pituitous substances and other effective components, and can improve local blood circulation, promote epithelial cell repair, eliminate skin scars, relieve pigmentation, whiten skin and remove spots; the contained polysaccharide component can obviously remove free radicals of the skin and has the effects of resisting oxidation and removing wrinkles. The lysimachia christinae hance extract has the effects of clearing away damp-heat, treating stranguria, reducing swelling and the like, is often used as a medicinal component for treating heat stranguria, sand stranguria, unsmooth and painful urination, jaundice and dark urine, carbuncle swelling and furuncle, venomous snake bite; calculus of liver and gallbladder, and lithangiuria.

The sage extract has good effects of controlling oil, astringing pores, resisting inflammation, removing acne and compacting skin. The flos Buddlejae extract can inhibit the generation of active oxygen, and effectively scavenge free radicals; preventing skin inflammation by inhibiting 5-lipoxygenase, cyclooxygenase-2 and UVB-induced TNF alpha; can inhibit melanin deposition, promote whitening, improve skin brightness, and keep skin young and good; at the same time, it maintains the physiological state of the normal skin by protecting the skin from light radiation (such as UV, blue light, infrared light, etc.).

The invention creatively carries out scientific compatibility on eight components of a buddleja officinalis extract, a kuh-seng root extract, a liquorice root extract, a scutellaria root extract, an angelica extract, a bletilla striata extract, a desmodium extract and a salvia extract, and each component carries out synergistic interaction on multiple dimensions. Particularly, the sophora flavescens extract and the salvia officinalis extract have obvious synergistic interaction effects on the aspects of controlling oil, dredging and astringing pores of the skin, so that the skin makeup removing effect is prevented; the scutellaria root extract, the desmodium extract and the salvia extract have obvious synergistic interaction effect on the aspects of diminishing inflammation and resisting allergy of the skin, so that the skin is relieved; the butterflybush flower extract, the sophora flavescens root extract, the glycyrrhiza inflate root extract, the scutellaria baicalensis root extract, the angelica sinensis extract and the bletilla striata extract respectively act on various ways of skin blackening to mutually cooperate, or effectively inhibit the activity of tyrosinase, efficiently remove oxygen free radicals, inhibit the generation of active oxygen, prevent the generation of melanin, or remove toxin impurities in the skin, or promote the growth and repair of damaged vascular nerve cells, recover the activity of subcutaneous capillary cells, expand the capillary vessels, and improve local blood circulation, thereby comprehensively improving the whiteness and the brightness of the skin. Meanwhile, the buddleja officinalis extract can effectively resist blue light damage to skin caused by long-term use of mobile phones, computers, panels and other display screens, isolate blue light, resist light invasion, repair light damage, and provide more advanced protection for the skin while decorating the skin, so that the health state of the skin is maintained. Moreover, the skin conditioner provided by the invention is a full traditional Chinese medicine component, does not contain other chemical synthesis components, and has the best skin adaptability and safety.

Preferably, the skin conditioner further comprises any one or combination of at least two of tranexamic acid, decarboxylated carnosine, fullerene, glucosyl rutin or a hypsizygus marmoreus callus culture filtrate, wherein the combination of at least two of tranexamic acid and decarboxylated carnosine, the combination of fullerene and glucosyl rutin, the combination of glucosyl rutin and hypsizygus marmoreus callus culture filtrate and the like, and any other combination is not repeated here for convenience.

The skin conditioner is added with tranexamic acid, decarboxylated carnosine, fullerene, glucosyl rutin or hypsizygus marmoreus callus culture filtrate, so that the effects of whitening, resisting aging, balancing grease secretion and removing freckles can be further improved. Wherein the tranexamic acid mainly plays the roles of whitening, spot fading and making the skin to be white, soft, moist, bright and transparent; the decarboxylated carnosine, the fullerene and the glucosyl rutin mainly act on an oxidation path to prevent the damage of free radicals; the hypecoum polycarpum callus culture filtrate has effects of regulating skin pigmentation, keeping moisture, resisting oxidation, regulating skin keratinocyte formation, and stimulating skin healing.

Preferably, the skin conditioner comprises, by weight, 0.1-10 parts of a buddleja officinalis extract, 3-15 parts of a sophora flavescens root extract, 3-15 parts of a glycyrrhiza uralensis root extract, 3-15 parts of a scutellaria baicalensis root extract, 0.1-10 parts of an angelica sinensis extract, 0.1-10 parts of a bletilla striata extract, 0.1-10 parts of a lysimachia christinae extract, 0.01-1 part of a salvia officinalis extract, 0.1-10 parts of tranexamic acid, 0.1-10 parts of a carnosine decarboxylation, 0.01-1 part of fullerene, 1-30 parts of glucosyl rutin and 0.01-1 part of a hypsizygus marmoreus callus culture filtrate, based on the total weight of the skin conditioner.

According to the skin conditioner, the skin conditioner has the optimal effects of whitening, resisting aging, removing freckles, balancing grease secretion, preventing makeup loss, resisting blue light and the like by matching the components in parts by weight.

The weight parts of the buddleja officinalis extract can be 0.1 part, 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts and the like.

The parts by weight of the kushen root extract can be 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 10 parts, 12 parts, 14 parts or 15 parts and the like.

The liquorice root extract can be 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 10 parts, 12 parts, 14 parts or 15 parts by weight.

The scutellaria root extract can be 3, 4, 5, 6, 7, 8, 10, 12, 14 or 15 parts by weight.

The weight portion of the angelica extract can be 0.1 portion, 1 portion, 2 portions, 3 portions, 4 portions, 5 portions, 6 portions, 7 portions, 8 portions, 9 portions or 10 portions, etc.

The rhizoma bletillae extract can be 0.1 part, 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts by weight.

The weight parts of the lysimachia christinae hance extract can be 0.1 part, 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts and the like.

The weight portion of the sage extract can be 0.01 portion, 0.02 portion, 0.05 portion, 0.08 portion, 0.1 portion, 0.2 portion, 0.5 portion, 0.6 portion, 0.8 portion, 0.9 portion or 1 portion, etc.

The tranexamic acid may be present in an amount of 0.1, 1,2, 3, 4, 5, 6, 7, 8, 9, or 10 parts by weight.

The weight parts of the decarboxylated carnosine can be 0.1 part, 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts and the like.

The fullerene may be present in an amount of 0.01, 0.02, 0.05, 0.08, 0.1, 0.2, 0.5, 0.6, 0.8, 0.9, or 1 parts by weight.

The weight portion of the glucosyl rutin can be 1 portion, 2 portions, 5 portions, 8 portions, 10 portions, 15 portions, 20 portions, 22 portions, 25 portions, 28 portions or 30 portions and the like.

The parts by weight of the hypecoum vulgare callus culture filtrate can be 0.01 part, 0.02 part, 0.05 part, 0.08 part, 0.1 part, 0.2 part, 0.5 part, 0.6 part, 0.8 part, 0.9 part or 1 part and the like.

On the other hand, the invention provides a makeup-removal-preventing blue-light-resisting skin-care cream, which is prepared from the raw materials of, by weight, 0.05-4 parts of the skin conditioner, 2-25 parts of a humectant, 1-20 parts of an emollient, 1-5 parts of an emulsifier and 60-85 parts of water.

The skin conditioner related to the invention is mixed with the humectant, the emollient, the emulsifier and the water which are conventional ingredients of cosmetics to obtain the skin-care cream with the effects of preventing makeup loss and resisting blue light. Wherein the skin conditioner and other components are used in combination according to the proportion relationship.

The skin conditioner may be present in an amount of 0.05 parts, 0.1 parts, 0.2 parts, 0.5 parts, 1 part, 2 parts, 3 parts, or 4 parts by weight.

The humectant can be 2 parts, 3 parts, 5 parts, 8 parts, 10 parts, 12 parts, 15 parts, 18 parts, 20 parts, 22 parts, 24 parts or 25 parts by weight and the like.

The emollient may be in the range of 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 10 parts, 12 parts, 15 parts, or 20 parts by weight.

The emulsifier can be 1 part, 2 parts, 3 parts, 4 parts or 5 parts by weight.

The water may be present in an amount of 60 parts, 65 parts, 70 parts, 75 parts, 80 parts, 85 parts, or the like.

Preferably, the raw materials for preparing the facial cream further comprise any one or combination of at least two of 1-5 parts of thickening agent, 1-5 parts of freckle removing agent, 0.5-1 part of antioxidant, 0.1-0.2 part of preservative or 0.01-0.3 part of aromatic, wherein the combination of at least two of the thickening agent and the freckle removing agent, the antioxidant and the preservative, the antioxidant and the aromatic and the like, and any other combination is convenient and is not repeated herein.

The weight portion of the thickening agent can be 1 part, 2 parts, 3 parts, 4 parts or 5 parts and the like.

The spot removing agent can be 1 part, 2 parts, 3 parts, 4 parts or 5 parts by weight.

The antioxidant may be present in an amount of 0.5, 0.6, 0.7, 0.8, 0.9, or 1 part by weight.

The preservative can be 0.1 part, 0.12 part, 0.14 part, 0.15 part, 0.18 part or 0.2 part by weight and the like.

The weight portion of the aromatic can be 0.01 portion, 0.02 portion, 0.05 portion, 0.1 portion, 0.15 portion, 0.2 portion, 0.25 portion, 0.28 portion or 0.3 portion, etc.

Preferably, the humectant comprises any one or combination of at least two of glycerin, panthenol, 1, 2-hexanediol, or butanediol, such as a combination of glycerin and panthenol, a combination of 1, 2-hexanediol and butanediol, a combination of panthenol and 1, 2-hexanediol, and the like, and any other combination is not described herein for convenience.

Preferably, the emollient comprises any one or combination of at least two of hydrogenated methyl rosinate, polydimethylsiloxane, or isononyl isononanoate, such as a combination of hydrogenated methyl rosinate and polydimethylsiloxane, a combination of polydimethylsiloxane and isononyl isononanoate, a combination of hydrogenated methyl rosinate and isononyl isononanoate, and the like, and any other combination is not repeated herein for convenience.

Preferably, the emulsifier includes any one or a combination of at least two of polyacrylamide, isoparaffin, laureth-7, ethylhexyl stearate, sodium polyacrylate or trideceth-6, for example, a combination of polyacrylamide and isoparaffin, a combination of laureth-7 and ethylhexyl stearate, a combination of sodium polyacrylate and trideceth-6, and the like, and any combination is not described herein for convenience.

Preferably, the thickener comprises titanium dioxide and/or triethoxyoctylsilane.

The raw powder materials of the titanium dioxide and/or triethoxyoctylsilane are all hollow spherical powder structures with the particle size not larger than 1 mu m, and when the powder is combined with sebum and sweat, water and oil can be absorbed in the hollow sphere, so that the makeup can be attached to the surface of skin more durably, and the makeup removal phenomenon caused by the sweat and the oil is reduced.

Preferably, the spot removing agent comprises niacinamide and/or glycyrrhiza glabra root extract.

Preferably, the antioxidant comprises p-hydroxyacetophenone.

Preferably, the preservative comprises methylparaben.

In another aspect, the invention provides a preparation method of the above make-up prevention and blue light resistant facial cream, comprising the following steps:

(1) mixing the water phase components in the humectant, the emulsifier and the emollient with water, and stirring to obtain a water phase mixed solution; mixing the oil phase components in the humectant, the emulsifier and the emollient to obtain an oil phase mixed solution;

(2) mixing the water phase mixed liquor and the oil phase mixed liquor obtained in the step (1), stirring and homogenizing to obtain a homogenized liquor;

(3) and (3) mixing and stirring the homogeneous liquid obtained in the step (2) and a skin conditioner to obtain the makeup-removal-preventing blue-light-resistant face cream.

Preferably, the temperature at which the aqueous phase component of step (1) is mixed with water is 80-85 ℃, such as 80 ℃, 81 ℃, 82 ℃, 83 ℃, 84 ℃ or 85 ℃ and the like.

Preferably, the time for mixing the water phase component and water in step (1) is 5-10min, such as 5min, 6min, 7min, 8min, 9min or 10 min.

Preferably, the temperature at which the oil phase ingredients are mixed in step (1) is 78-80 ℃, such as 78 ℃, 79 ℃ or 80 ℃, and the like.

Preferably, the oil phase components of step (1) are mixed for 5-10min, such as 5min, 6min, 7min, 8min, 9min or 10 min.

Preferably, the temperature for mixing and homogenizing in the step (2) is 80-82 ℃, such as 80 ℃, 81 ℃ or 82 ℃ and the like.

Preferably, the mixing and homogenizing time in step (2) is 3-8min, such as 3min, 4min, 5min, 6min or 8 min.

Preferably, the temperature of the mixing in step (3) is 40-50 deg.C, such as 40 deg.C, 42 deg.C, 44 deg.C, 45 deg.C, 46 deg.C, 47 deg.C, 48 deg.C or 50 deg.C.

Preferably, the mixing time in step (3) is 10-20min, such as 10min, 12min, 14min, 15min, 16min, 18min or 20min, etc.

The preparation process of the face cream provided by the invention needs to be sequentially carried out under the three steps, and the water phase component mixing, the oil phase component mixing, the emulsification homogenization and the final mixing with the skin conditioner have respective specific temperature and time requirements, so that the efficacy of the finally prepared product can be maximized only according to the matching relationship strictly.

As a preferred technical scheme, the preparation method of the makeup removal-preventing and blue-light-resisting facial cream comprises the following steps:

(1) mixing the water phase components of humectant, emulsifier and emollient with water at 80-85 deg.C for 5-10min to obtain water phase mixed solution; mixing oil phase components of humectant, emulsifier and emollient at 78-80 deg.C for 5-10min to obtain oil phase mixture;

(2) mixing the water phase mixed solution and the oil phase mixed solution obtained in the step (1) at 80-82 ℃ and homogenizing for 3-8min to obtain a homogeneous solution;

(3) and (3) mixing the homogenized liquid obtained in the step (2) with a skin conditioner, a thickening agent, a freckle removing agent, an antioxidant, a preservative and an aromatic at 40-50 ℃ for 10-20min to obtain the makeup-preventing and blue-light-resisting facial cream.

Compared with the prior art, the invention has the following beneficial effects:

the skin conditioner is prepared by creatively and scientifically mixing eight components, namely a butterflybush flower extract, a sophora flavescens root extract, a liquorice root extract, a scutellaria baicalensis root extract, an angelica sinensis extract, a bletilla striata extract, a desmodium extract and a salvia officinalis extract, and the components are synergized in multiple dimensions, so that the skin conditioner has the effects of remarkably controlling oil, dredging and astringing pores, balancing skin grease secretion and preventing makeup removal; has remarkable effects of diminishing inflammation, resisting allergy and relieving skin; the whitening and brightness of the skin can be remarkably improved, the skin color can be modified, and the anti-aging effect can be achieved; meanwhile, the blue light-shielding material has the effects of shielding blue light, resisting light invasion and repairing light damage. Part of the raw materials are hollow spherical powder structures, and after the powder is combined with sebum and sweat, water and oil can be absorbed in the hollow sphere, so that makeup is attached to the surface of skin more durably, and the makeup removal phenomenon caused by sweat and oil is further reduced. The skin conditioner provided by the invention is a full traditional Chinese medicine component, does not contain other chemical synthesis components, and has good skin adaptability and safety. And has good air permeability, water wettability and extensibility.

Detailed Description

To further illustrate the technical means and effects of the present invention, the following further describes the technical solution of the present invention with reference to the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.

Example 1

The embodiment provides a skin-care cream, which comprises the following preparation raw materials in parts by weight of 100:

the preparation method comprises the following steps:

(1) mixing panthenol, ethylhexyl stearate, sodium polyacrylate and water at 85 deg.C for 8min to obtain water phase mixed solution; mixing hydrogenated methyl rosinate and polydimethylsiloxane at 80 ℃ for 5min to obtain an oil phase mixed solution;

(2) mixing the water phase mixed liquor and the oil phase mixed liquor obtained in the step (1) at 82 ℃ and homogenizing for 5min to obtain homogenized liquor;

(3) and (3) mixing the homogenized solution obtained in the step (2) with a butterflybush flower extract, a sophora flavescens root extract, a liquorice root extract, a scutellaria baicalensis root extract, an angelica sinensis extract, a bletilla striata extract, a desmodium extract and a salvia officinalis extract at 40 ℃ for 10min to obtain the anti-makeup and blue light-resistant pigment cream.

Example 2

the preparation method comprises the following steps:

(1) mixing panthenol, ethylhexyl stearate, sodium polyacrylate and water at 80 deg.C for 10min to obtain water phase mixed solution; mixing hydrogenated methyl rosinate and polydimethylsiloxane at 78 ℃ for 10min to obtain oil phase mixed solution;

(2) mixing the water phase mixed liquor and the oil phase mixed liquor obtained in the step (1) at 80 ℃ and homogenizing for 8min to obtain a homogeneous liquor;

(3) and (3) mixing the homogenized solution obtained in the step (2) with a butterflybush flower extract, a sophora flavescens root extract, a glycyrrhiza dilatata root extract, a scutellaria baicalensis root extract, an angelica sinensis extract, a bletilla striata extract, a lysimachia christinae extract, a salvia officinalis extract, tranexamic acid, decarboxycarnosine, fullerene, glucosyl rutin and a hypsizygus marmoreus callus culture filtrate at 50 ℃ for 10min to obtain the anti-makeup and anti-blue-light face cream.

Example 3

the preparation method comprises the following steps:

(1) mixing panthenol, ethylhexyl stearate, sodium polyacrylate, methyl hydroxybenzoate and water at 80 deg.C for 10min to obtain water phase mixed solution; mixing hydrogenated methyl rosinate, polydimethylsiloxane and titanium dioxide at 78 ℃ for 10min to obtain an oil phase mixed solution;

(2) mixing the water phase mixed liquor and the oil phase mixed liquor obtained in the step (1) at 82 ℃ and homogenizing for 3min to obtain homogenized liquor;

(3) and (3) mixing the homogenized liquid obtained in the step (2) with a butterflybush flower extract, a sophora flavescens root extract, a glycyrrhiza flatsedge root extract, a scutellaria baicalensis root extract, an angelica sinensis extract, a bletilla striata extract, a lysimachia christinae extract, a salvia officinalis extract, tranexamic acid, decarboxylic carnosine, fullerene, glucosyl rutin, a hypsizygus marmoreus callus culture filtrate, nicotinamide and a glycyrrhiza glabra root extract at 45 ℃ for 10min to obtain the anti-make-up and blue light resistant skin cream.

Example 4

The embodiment provides a pigment cream which comprises the following preparation raw materials in parts by weight of 100:

raw materials	Parts by weight
		Flos Buddlejae extract	0.5
Extract of kuh-seng root	0.2
		Glycyrrhiza inflata root extract	0.5
Scutellaria root extract	0.3
		Angelica sinensis extract	0.2
Bletilla striata extract	0.3
		Herba Lysimachiae Christinae extract	0.5
Salvia officinalis extract	0.1
		Tranexamic acid	0.05
Decarboxypeptide	0.1
		Fullerene	0.01
Glucosyl rutin	1
		Craib seed callus culture filtrate	0.02
Panthenol	10
		Glycerol	5
1, 2-hexanediol	0.5
		Hydrogenated abietic acid methyl ester	5
Isononyl isononanoate	1
		Polydimethylsiloxane	5
Ethyl hexyl stearate	3
		Polyacrylamide sodium salt	1
Tridecyl alcohol polyether-6	0.1
		Laureth-7	0.05
Titanium dioxide	1
		Triethoxyoctylsilane	0.5
Nicotinamide	1
		Glycyrrhiza glabra root extract	0.01
P-hydroxyacetophenone	0.5
		Hydroxy phenyl methyl ester	0.2
Essence	0.01
		Water (W)	To 100

The preparation method comprises the following steps:

(1) mixing panthenol, ethylhexyl stearate, sodium polyacrylate, methyl hydroxybenzoate, tridecyl alcohol polyether-6, methyl hydroxybenzoate and water at 80 deg.C for 10min to obtain water phase mixed solution; mixing hydrogenated methyl abietate, polydimethylsiloxane, isononyl isononanoate, triethoxyoctylsilane and titanium dioxide at 78 ℃ for 10min to obtain an oil phase mixed solution;

(2) mixing the water phase mixed solution and the oil phase mixed solution obtained in the step (1) at 82 ℃ for homogenizing for 5min to obtain a homogenized solution, and then adding glycerol, 1, 2-hexanediol and p-hydroxyacetophenone for mixing and homogenizing for 5 min;

(3) and (3) mixing the homogenized liquid obtained in the step (2) with a butterflybush flower extract, a sophora flavescens root extract, a licorice root extract, a scutellaria baicalensis root extract, an angelica sinensis extract, a bletilla striata extract, a lysimachia christinae extract, a salvia officinalis extract, tranexamic acid, decarboxypeptide, fullerene, glucosyl rutin, a hypsizygus marmoreus callus culture filtrate, nicotinamide, a glycyrrhiza glabra root extract, laureth-7 and essence at 45 ℃ for 10min to obtain the anti-makeup and anti-blue-light essence facial cream.

Comparative example 1

The comparative example provides a skin-whitening cream, and the raw materials for preparing the skin-whitening cream are different from those in example 1 only in that the skin-whitening cream does not contain the butterflybush flower extract, the weight part of the sophora flavescens root extract is 1 part, and the rest parts are consistent. The preparation method is the same as that of example 1.

Comparative example 2

The comparative example provides a pigment cream, and the raw materials for preparing the pigment cream are different from those in example 1 only in that the pigment cream does not contain the sophora flavescens root extract, the weight part of the buddleja officinalis extract is 1 part, and the rest parts are the same. The preparation method is the same as that of example 1.

Comparative example 3

The present comparative example provides a skin-beautifying cream whose preparation raw materials differ from those of example 1 only in that glycyrrhiza inflata root extract is not contained and the weight part of salvia officinalis extract is 0.6 parts, and the others are the same. The preparation method is the same as that of example 1.

Comparative example 4

The present comparative example provides a skin cream whose preparation raw materials differ from example 1 only in that sage extract is not contained and the weight part of glycyrrhiza inflate trogii root extract is 0.6 parts, and the others are identical. The preparation method is the same as that of example 1.

Comparative example 5

The comparative example provides a skin-beautifying cream, and the raw materials for preparing the skin-beautifying cream are different from those in example 1 only in that the radix scutellariae extract is not contained, the weight part of the herba lysimachiae extract is 1.5 parts, and the rest parts are consistent. The preparation method is the same as in example 1.

Comparative example 6

The comparative example provides a pigment-removing cream, and the raw materials for preparing the pigment-removing cream are different from those in example 1 only in that the herba lysimachiae extract is not contained, and the weight part of the scutellaria baicalensis root extract is 1.5 parts, and the rest is consistent. The preparation method is the same as that of example 1.

Example 5

This example provides a skin-care cream, which is prepared from the same raw materials as in example 1, and the preparation method is different from example 1 only in that the mixing temperature in step (3) is 60 ℃, the mixing time is 5min, and the rest is the same.

Example 6

This example provides a skin-care cream, which is prepared from the same raw materials as in example 1, and the preparation method is different from example 1 only in that the mixing temperature in step (2) is 90 ℃, the mixing time is 5min, and the rest is the same.

Evaluation test:

(1) reactive oxygen species level evaluation of cells under blue light pressure:

the specific method comprises the following steps: healthy SD rats 72, weighing around 200g, and males were selected and randomly divided into 12 groups of 6 animals each corresponding to the products of examples 1-6 and comparative examples 1-6, respectively. The rat had hair removed from its back and had an area of about 2X 2cm, in the blue light of the LED at 425nm (3 mW/cm) ² Lasting for 18min), respectively smearing the tested samples on naked skin of a rat, wherein the smearing amount of each group is 0.1g/cm, quantitatively analyzing by using CellROX fluorescence intensity staining and Volocity image analysis software after 24h, wherein the larger the value of the cellular active oxygen, the worse the blue light resistance of the tested samples is, continuously using for three weeks, and recording the change condition of the cellular active oxygen of the rat skin once every week.

The results are shown in Table 1.

TABLE 1

From the data in table 1: the skin-whitening cream has remarkable blue light resisting effect, and the reactive oxygen species level of cells is obviously reduced under the blue light pressure from day 0 to day 21. And as can be seen from the comparison of the data of the examples and the comparative examples, the main component is the extract of the butterflybush flower, and the mixing temperature and the mixing time of the skin conditioner during the preparation of the skin-care cream have important influence on the final blue-light resistant effect of the product.

(2) Evaluation test for melanin inhibition:

the specific method comprises the following steps: b16 cells in logarithmic phase are digested and dispersed to prepare single cell suspension, and the single cell suspension is counted. Cells were seeded in 6-well cell culture plates at a seeding density of 1X 10 ⁶ And (2) each well, keeping the liquid amount at 2mL per well overnight, after the cells adhere to the wall, absorbing the culture solution, replacing the solution with each test sample (each g of the sample is diluted by 100mL of culture medium) and a positive control drug (arbutin 50 mu g/mL of culture medium) for 1 time, only adding the culture medium into a blank control group, continuing to culture for 72 hours, collecting the cells by trypsin after the drug treatment is finished, washing the cells by PBS for 3 times after centrifugation, adding 20 mu L of distilled water to suspend the precipitate, adding 200 mu L of ethanol-diethyl ether (1:1) mixed solution, standing for 20 minutes at room temperature, centrifuging for 5 minutes at 3000r/min, adding 2000 mu L of 1N sodium hydroxide (containing 10% of DMSO) into the precipitate, incubating for 30 minutes in a water bath at 80 ℃, and measuring the absorbance at 420nm by using a microplate reader. Melanin synthesis inhibition rate ═ 1- (drug-treated absorbance value/drug-treated cell number)/(blank absorbance value/blank cell number)]×100％。

The results are shown in Table 2.

TABLE 2

From the data in table 2 it can be seen that: the skin-care cream has an obvious melanin synthesis inhibiting effect, wherein the butterflybush flower extract, the glycyrrhiza inflate extract and the scutellaria baicalensis root extract play main roles, an obvious synergistic effect exists among the butterflybush flower extract, the glycyrrhiza inflate extract and the scutellaria baicalensis root extract, and the mixing temperature and time of a skin conditioner during preparation of the skin-care cream have obvious influence on the final melanin synthesis inhibiting effect of a product.

(3) And (3) antioxidant activity test:

the specific method comprises the following steps: preparing 1mM stock solution of a test article and a positive control arbutin, adding 1.4mg of DPPH into 17.5mL of absolute ethanol to obtain 0.2mmol/L DPPH solution, adding 100 mu L of diluent of the stock solution into a 96-well enzyme label plate, and then adding 100 mu L of the DPPH solution to ensure that the final concentration of the test article is 100 mu M. And (3) after the enzyme label plate is kept at 30 ℃ for 30min, measuring the absorbance value (As) of the enzyme label plate at the wavelength of 517nm, simultaneously measuring the absorbance value (Ac) of a sample blank (which replaces DPPH by absolute ethyl alcohol) without adding a DPPH free radical reagent and the absorbance value (Amax) of a sample (which replaces the sample by absolute ethyl alcohol) with adding DPPH but without adding the sample, and calculating the relative clearance rate (%) < 1- (As-Ac)/Amax >. times.100%.

The results are shown in Table 3.

TABLE 3

From the data in table 3: the essence cream has an obvious effect of removing free radicals, wherein the butterflybush flower extract, the glycyrrhiza inflata root extract, the scutellaria baicalensis root extract and the sophora flavescens root extract play main roles, the four have an obvious synergistic effect, and the mixing temperature and time of a skin conditioner during preparation of the essence cream have an obvious influence on the final effect of removing the free radicals of a product.

(4) VISIA skin assay evaluation test:

the specific method comprises the following steps: 70 women of aged skin aged 30 to 40 years old were selected and randomly divided into 7 groups of 10 persons each, and the products of example 1 and comparative examples 1 to 6 were used, respectively. The subjects were on a continuous basis, with product application 2 times a day, morning and evening, on 28 consecutive trial days, and asked for a visit on days 14 (D14) and 28 (D28) of the trial. The test of the same subject is performed by the same measuring person. A photograph of the face of the subject was taken with a VISIA facial image analyzer in a room at room temperature of 22 ℃. + -. 2 ℃ and a relative humidity of 40. + -.2%. The face (including the front, the left side and the right side) of the subject is photographed, data statistics is carried out on the sum of absolute scores, and the detection data of the pigment spots, the textures and the wrinkles of the face of the subject is recorded (the higher the data, the more serious the phenomena of the pigment spots, the textures and the wrinkles appear).

The results are shown in Table 4.

TABLE 4

From the data in table 4, it can be seen that: compared with comparative examples 1-6, the skin conditioner of example 1 has more obvious improved effects on pigment spots, wrinkles and textures of a subject, and the skin conditioner of the invention has synergistic effect on relieving pigment spots, wrinkles and textures.

(5) Human body trial evaluation test:

the facial cream prepared in the examples 1-6 and the comparative examples 1-6 is selected to be used for human trial evaluation tests, and volunteers evaluate the air permeability, the water wettability, the extensibility and the makeup-holding effect for 12h of the facial cream in the using process, wherein the highest score is 5, the lowest score is 1, and any value between 1 and 5 can be taken.

The test results are shown in table 5.

TABLE 5

From the data in table 5, it can be seen that: the skin-beautifying cream provided by the invention has obvious improvement on the aspects of air permeability, water wettability, extensibility and make-up maintaining effect. Especially, the bitter ginseng root extract and the sage extract have outstanding contribution to the make-up effect, and the two have synergistic effect.

(6) Evaluation test of skin irritation:

the skin irritation evaluation test was performed on the skin creams prepared in examples 1 to 4 and comparative examples 1 to 2, and the test method was as follows:

12 women and 12 men were used as test subjects and were randomly divided into 6 groups, and 2 women and 2 men in each group were sampled with a syringe (1g of the test article was dissolved in 100mL of PBS) in a chamber of a spot test tape, and the spot test tape with the sample placed therein was immediately attached to the normal skin of the left forearm of the subject from the lower part in the longitudinal direction while gently pressing the chamber one by one to expel air and to distribute the sample uniformly. The test site is marked for easy observation. The patch was applied every 24 hours and then removed for a second half hour and examined according to the CTFA guidelines for a total of 5 patch tests. On day 6 after the completion of skin application, additional examination was performed to observe delayed reactions, and data was compared using the last examination result.

The criteria for the skin irritation test are shown in table 6:

TABLE 6

The test results are shown in table 7:

TABLE 7

Number of times of skin sticking	Example 1	Example 2	Example 3	Example 4	Comparative example 1	Comparative example 2
							1	0	0	0	0	0	0
2	0	0	0	0	0	0
							3	0	0	0	0	0	0
4	0	0	0	0	0	0
							5	0	0	0	0	0	0
Day 6 after completion	0	0	0	0	0	0
							Total up to	0	0	0	0	0	0

According to the test results, the face cream disclosed by the invention has no stimulation to skin and no positive reaction, and the product disclosed by the invention is safe and high in mildness.

The applicant states that the present invention is illustrated by the above examples, but the present invention is not limited to the above examples, i.e. the present invention is not meant to be implemented only by relying on the above examples. It should be understood by those skilled in the art that any modification of the present invention, equivalent substitutions of the raw materials of the product of the present invention, addition of auxiliary components, selection of specific modes, etc., are within the scope and disclosure of the present invention.

The preferred embodiments of the present invention have been described in detail, however, the present invention is not limited to the specific details of the above embodiments, and various simple modifications may be made to the technical solution of the present invention within the technical idea of the present invention, and these simple modifications are within the protective scope of the present invention.

It should be noted that the various technical features described in the above embodiments can be combined in any suitable manner without contradiction, and the invention is not described in any way for the possible combinations in order to avoid unnecessary repetition.

Claims

1. The makeup-removal-preventing and blue-light-resisting skin cream is characterized by comprising, by weight, 0.05-4 parts of a skin conditioner, 2-25 parts of a humectant, 1-20 parts of an emollient, 1-5 parts of an emulsifier and 60-85 parts of water;

based on the total weight of the skin conditioner, the skin conditioner comprises, by weight, 0.1-10 parts of butterflybush flower extract, 3-15 parts of sophora flavescens root extract, 3-15 parts of glycyrrhiza inflate root extract, 3-15 parts of scutellaria baicalensis root extract, 0.1-10 parts of angelica sinensis extract, 0.1-10 parts of bletilla striata extract, 0.1-10 parts of lysimachia christinae extract, 0.01-1 part of salvia officinalis extract, 0.1-10 parts of tranexamic acid, 0.1-10 parts of decarboxylated carnosine, 0.01-1 part of fullerene, 1-30 parts of glucosyl rutin and 0.01-1 part of hypusine callus culture filtrate;

the emulsifier comprises any one or a combination of at least two of polyacrylamide, isoparaffin, laureth-7, ethylhexyl stearate, sodium polyacrylate or trideceth-6;

the makeup removal-preventing and blue light-resistant vegetarian cream is prepared by a preparation method comprising the following steps of:

(1) mixing the water phase components in the humectant, the emulsifier and the emollient with water, and stirring to obtain a water phase mixed solution; mixing and stirring oil phase components in the humectant, the emulsifier and the emollient to obtain an oil phase mixed solution;

(3) and (3) mixing the homogenized liquid obtained in the step (2) with a skin conditioner at 40-50 ℃ and stirring for 10-20min to obtain the makeup-removal-preventing blue-light-resistant face cream.

2. The make-up prevention and blue light resistant facial cream according to claim 1, wherein the raw materials for preparing the facial cream further comprise any one or a combination of at least two of 1-5 parts by weight of a thickening agent, 1-5 parts by weight of a freckle removing agent, 0.5-1 part by weight of an antioxidant, 0.1-0.2 part by weight of a preservative or 0.01-0.3 part by weight of an aromatic.

3. The make-up reduction and blue-light resistant skin cream of claim 1, wherein the moisturizer comprises any one or a combination of at least two of glycerin, panthenol, 1, 2-hexanediol, or butanediol.

4. The anti-makeup and blue-light resistant facial cream of claim 1, wherein said emollient comprises any one or a combination of at least two of methyl hydrogenated rosinate, polydimethylsiloxane, or isononyl isononanoate.

5. The make-up reduction and blue light resistant facial cream of claim 2, wherein the thickener comprises titanium dioxide and/or triethoxyoctylsilane.

6. The make-up reduction and blue-light resistant facial cream of claim 2, wherein the spot removing agent comprises niacinamide and/or glycyrrhiza glabra root extract.

7. The make-up reduction and blue light resistant skin cream of claim 2, wherein the antioxidant comprises p-hydroxyacetophenone.

8. The make-up reduction and blue light resistant facial cream of claim 2, wherein the preservative comprises methylparaben.

9. The preparation method of the makeup removal-preventing blue-light-resistant face cream according to claim 1, wherein the preparation method comprises the following steps:

(1) mixing the water phase components in the humectant, the emulsifier and the emollient with water, and stirring to obtain a water phase mixed solution; mixing and stirring oil phase components in the humectant, the emulsifier and the emollient to obtain oil phase mixed solution;

10. The method for preparing the makeup removal and blue light resistant facial cream according to claim 9, wherein the temperature of the water phase component mixed with water in the step (1) is 80-85 ℃.

11. The make-up removal and blue light resistant facial cream of claim 9, wherein the time for mixing the water phase component and water in step (1) is 5-10 min.

12. The make-up removal and blue-light resistant facial cream of claim 9, wherein the oil phase components in step (1) are mixed at a temperature of 78-80 ℃.

13. The make-up removal and blue-light resistant facial cream of claim 9, wherein the oil phase ingredients in step (1) are mixed for 5-10 min.

14. The method for preparing the makeup removal-resistant and blue-light-resistant facial cream according to claim 9, comprising the following steps: