CN109528603A - Lightening compositions, whitening brightening cream comprising lightening compositions and preparation method thereof - Google Patents

Lightening compositions, whitening brightening cream comprising lightening compositions and preparation method thereof Download PDF

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Publication number
CN109528603A
CN109528603A CN201910064750.8A CN201910064750A CN109528603A CN 109528603 A CN109528603 A CN 109528603A CN 201910064750 A CN201910064750 A CN 201910064750A CN 109528603 A CN109528603 A CN 109528603A
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parts
extracting solution
lightening compositions
whitening
root
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琚建伟
段毅鹏
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Shanghai Tong Yan Industrial Co Ltd
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Shanghai Tong Yan Industrial Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
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    • A61K8/9728Fungi, e.g. yeasts
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    • A61K8/00Cosmetics or similar toiletry preparations
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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Abstract

The present invention provides a kind of lightening compositions, whitening brightening cream comprising lightening compositions and preparation method thereof, the whitening brightening cream includes the component of following mass percent: 0.1%-20% lightening compositions, 1%-25% moisturizer, 1%-5% emulsifier, 1%-20% moisturizing grease, 0.1%-5% skin conditioning agent, 0.05%-3% penetration-assisting agent, 0.01%-1% chelating agent, 0.1%-1% thickener, 0%-1% essence and 0.05%-2% preservative, surplus are deionized water.Lightening compositions of the invention are had effects that cooperate with whitening and are reduced irritation from whitening agent niacinamide traditional with eight kinds of ginseng, the root bark of white mulberry, Radix Angelicae Sinensis, Radix Glycyrrhizae, tealeaves, Black Ganoderma, root of kirilow rhodiola, ginkgo leaf Chinese medicine extracting solutions and Trenaxmine.The skin sense of whitening brightening cream of the invention is moistened without sticky, is easily absorbed, and whitening skin lightening result is significant.

Description

Lightening compositions, whitening brightening cream comprising lightening compositions and preparation method thereof
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of whitening brightening cream comprising lightening compositions and its preparation side Method.
Background technique
Whitening skin lightening is the eternal topic of skin nursing, and compatriots are pursuing the tender skin of pale cunning, ancient prescription from ancient times to the present 800 diffusings reach the present.With the raising of chemical industry synthesis technology, more and more synthesis of chemicals raw materials are used for whitening, thus Also many adverse reactions and safety accident, such as Japanese rhododendrol event, state's internal hormone face are produced.Health, safely, feel at ease With it is effective, have become the synonym of new era whitening.Chinese herbal medicine is because pass through verifying in thousands of years, safety and effect quilt Modern increasingly receives, and Chinese medicine whitening raw materials also become market popularity trend.The existing true white-skinned face function of the market demand, again Not violated addition hormone medicine, and the whitening product to skin-safe that has no adverse reaction.
The mechanism that human skin melanin is formed is more complicated, and gene, living environment etc. all have directly skin color Connect influence, Asian skin's color is mainly determined by melanin quantity in epidermis, reduce melanin presentation can be obtained it is pale Effect.The forming process of the black pigment of skin include the migration of melanocyte, the division of melanocyte mature, formation of melanosome, The physiological and biochemical procedure of a series of complex such as the transhipment of melanin granule and the excretion of melanocyte.Come from the angle of biochemical reaction It sees, the formation of melanocyte must be there are three types of base substance: tyrosine is the primary raw material for manufacturing melanocyte;Tyrosinase is that tyrosine turns Become the major rate-limiting enzyme of melanocyte, is the composition of copper and protein;Tyrosine generates melanocyte under the action of tyrosinase, secondary Kind effect is oxidation process, it is necessary to can just be changed into melanocyte in conjunction with oxygen.
The principle of whitening is mainly exactly to be formed by inhibiting tyrosinase to reduce melanin, prevents the black produced Element is transferred to epidermis, and the melanin that decomposition-reduction has been formed, and there are also be exactly directly to accelerate falling off for epidermal cell.At present Main whitening composition has arbutin, derivative of kojic acid, ascorbic acid derivates, hydroquinone derivatives etc. in the market, these whitenings Agent has significant whitening effect, but there is also skin irritatin, photaesthesia, cytotoxicity and is easy the problems such as changing colour.
Summary of the invention
For the existing various deficiencies of whitening skin lightening product, the present invention provides a kind of lightening compositions, using eight kinds of Chinese medicines Extracting solution is used in compounding with niacinamide and Trenaxmine, and safe and effective whitening purpose is reached from number of ways.The present invention is in addition One purpose provides a kind of above-mentioned whitening brightening cream and preparation method thereof comprising lightening compositions.
The lightening compositions for including in the present invention include the component of following parts by weight: 0.1-10 parts of ginseng extracts Liquid, 0.1-10 parts of root bark of white mulberry extracting solution, 0.1-10 parts of angelica root extracting solution, 0.1-10 parts of licorice extracting solution, 0.1- 10 parts of tea extract, 0.1-10 parts of Black Ganoderma extracting solution, 0.1-10 parts of ginkgo biloba succi, 0.1-10 parts of red scape Tiangeng extracting solution, 0.5-10 parts of niacinamide and 0.1-10 parts of Trenaxmine.
The preparation methods of lightening compositions provided by the invention the following steps are included:
Step 1: prepare ginseng extracting solution, root bark of white mulberry extracting solution, angelica root extracting solution, licorice extracting solution, tealeaves and mention Take liquid, Black Ganoderma extracting solution, ginkgo biloba succi, root of Rhodiola sachalinensis extracting solution, niacinamide and Trenaxmine.
Step 2: it requires to prepare the amount of each component according to formula rate number, mixes, stir evenly to obtain the final product.
Wherein, the extraction process of the ginseng extracting solution are as follows: choose the ginseng without mildew, clean and dry, after slice Ultrasonic Pulverization, the ethyl alcohol for measuring 70% concentration with 10 times impregnated 24 hours, then with Soxhlet extractor heating and refluxing extraction 2 hours, mistake Phegma is obtained after filter.In Rotary Evaporators, the ethyl alcohol in reflux extracting liquid is recycled, continues to be concentrated into mass ratio 1:1 to 1:2 Obtain concentrate.Concentrate is diluted with the butanediol of the water and 5 times of concentrates of 5 times of concentrate weights again again, 5 DEG C of refrigeration 24-48 are small When, up to ginseng extracting solution after filtering.
Wherein, the extraction process of the root bark of white mulberry extracting solution are as follows: choose the root bark of white mulberry without mildew, clean and dry, after smashing to pieces Ultrasonic Pulverization, the ethyl alcohol for measuring 70% concentration with 10 times impregnated 24 hours, then with Soxhlet extractor heating and refluxing extraction 2 hours, mistake Phegma is obtained after filter.In Rotary Evaporators, the ethyl alcohol in reflux extracting liquid is recycled, continues to be concentrated into mass ratio 1:1 to 1:2 Obtain concentrate.Concentrate is diluted with the butanediol of the water and 5 times of concentrates of 5 times of concentrate weights again again, 5 DEG C of refrigeration 24-48 are small When, root bark of white mulberry extracting solution after filtering.
Wherein, the angelica root takes the extraction process of liquid are as follows: chooses the angelica root without mildew, cleans and dry, surpasses after slice Sound crushes, and the ethyl alcohol for measuring 70% concentration with 10 times impregnated 24 hours, then with Soxhlet extractor heating and refluxing extraction 2 hours, filtering Phegma is obtained afterwards.In Rotary Evaporators, the ethyl alcohol in reflux extracting liquid is recycled, continues to be concentrated into mass ratio 1:1 to 1:2 obtaining Concentrate.Concentrate is diluted with the butanediol of the water of 5 times of concentrate weights and 5 times of concentrates weight again, 5 DEG C refrigeration 24-48 hours, Up to angelica root extracting solution after filtering.
Wherein, the extraction process of the licorice extracting solution are as follows: choose the glycyrrhiza glabra root without mildew, clean and dry, smash Ultrasonic Pulverization after broken was impregnated 24 hours with 10 times of 30% concentration ethanols of amount, then with Soxhlet extractor heating and refluxing extraction 2 hours, Phegma is obtained after filtering.In Rotary Evaporators, the ethyl alcohol in reflux extracting liquid is recycled, continues to be concentrated into mass ratio 1:1 and arrive 1:2 obtains concentrate.Concentrate is diluted with the butanediol of the water and 5 times of concentrates of 5 times of concentrate weights again again, 5 DEG C of refrigeration 24-48 Hour, up to licorice extracting solution after filtering.
Wherein, the extraction process of the tea extract are as follows: choose the tealeaves of white tea, clean and dry, shred, with 10 times Deionized water flows back 2-3 hours after impregnating, and phegma heating is concentrated into mass ratio 1:1 to 1:2 after filtering and obtains concentrate.It is added 10 times amount concentrate 60% concentration ethanol, after stirring 5 DEG C refrigeration 24-48 hours, by filtrate recycling ethanol after filtering, then plus Enter the butanediol with filtrate equivalent to get tea extract.
Wherein, the extraction process of the Black Ganoderma extracting solution are as follows: the Black Ganoderma without mildew is chosen, cleans and dries, ultrasonic powder It is broken, it flows back 2-3 hours after being impregnated with 10 times of deionized waters, phegma heating is concentrated into mass ratio 1:1 to 1:2 after filtering and is obtained Concentrate.Be added 10 times amount concentrate 70% concentration ethyl alcohol, after stirring 5 DEG C refrigeration 24-48 hours, by filtrate after filtering Ethyl alcohol is recycled, is added with the butanediol of filtrate equivalent to get Black Ganoderma extracting solution.
Wherein, the extraction process of the ginkgo biloba succi are as follows: choose the ginkgo leaf without mildew, clean and dry, shred, use 10 times of deionized water flows back 2-3 hours after impregnating, and phegma heating, which is concentrated into mass ratio 1:1 to 1:2, after filtering to be concentrated Liquid.Be added 10 times amount concentrate 60% concentration ethyl alcohol, after stirring 5 DEG C refrigeration 24-48 hours, filtrate is recycled after filtering Ethyl alcohol adds the butanediol with filtrate equivalent to get ginkgo biloba succi.
Wherein, the extraction process of the rhodiola extract are as follows: choose the root of kirilow rhodiola without mildew, clean and dry, after chopping Ultrasonic Pulverization, the ethyl alcohol for measuring 70% concentration with 10 times impregnated 24 hours, then with Soxhlet extractor heating and refluxing extraction 2 hours, mistake Phegma is obtained after filter.In Rotary Evaporators, the ethyl alcohol in reflux extracting liquid is recycled, continues to be concentrated into mass ratio 1:1 to 1:2 Obtain concentrate.Concentrate is diluted with the butanediol of the water and 5 times of concentrates of 5 times of concentrate weights again again, 5 DEG C of refrigeration 24-48 are small When, up to rhodiola extract after filtering.
In order to realize safe and effective whitening purpose, the whitening skin lightening comprising lightening compositions that the present invention also provides a kind of Frost, each component including following mass percent: 0.1%-20% (preferably 3-10%) lightening compositions, 1%-25% are (preferably 5-10%) moisturizer, 1%-5% (preferably 2-4%) emulsifier, 1%-20% (preferably 5-10%) moisturizing grease, 0.1%-5% (preferably 0.5-2%) skin conditioning agent, 0.05%-3% (preferably 0.5-2%) penetration-assisting agent, 0.01%-1% (preferably 0.05- 0.5%) chelating agent, 0.1%-1% (preferably 0.3-0.5%) thickener, 0%-1% (preferably 0.2%) essence and 0.05%- 2% (preferably 0.5%-1%) preservative, surplus is deionized water.
Preferably, the whitening brightening cream comprising lightening compositions includes component below: 1%- by mass percentage 20% lightening compositions, 5%-25% moisturizer, 2%-5% emulsifier, 5%-20% moisturizing grease, 0.1%-5% skin tune Manage agent, 0.05%-3% penetration-assisting agent, 0.01%-1% chelating agent, 0.1%-1% thickener, 0.05%-1% essence and 0.05%-2% preservative, surplus are deionized water.
Preferably, lightening compositions include each component of following parts by weight: 0.1-5 parts of ginseng extracting solution, 0.1-5 The root bark of white mulberry extracting solution, 0.1-5 parts of angelica root extracting solution, 0.1-5 parts of licorice extracting solution, 0.1-5 parts of tealeaves of part mention Take liquid, 0.1-5 parts of Black Ganoderma extracting solution, 0.1-5 parts of ginkgo biloba succi, 0.1-5 parts of root of Rhodiola sachalinensis extracting solution, 0.5- 10 parts of niacinamide, 0.1-10 parts of Trenaxmine.
The preparation method of the present invention also provides a kind of whitening brightening cream comprising lightening compositions comprising the steps of:
(1) deionized water, moisturizer, chelating agent, thickener and presumable high temperature Water-soluble preservatives are added in proportion Enter water phase pot, is heated with stirring to 90 ± 5 DEG C;
(2) oily phase pot is added in moisturizing grease, emulsifier and the molten preservative of presumable high temperature oil, is heated with stirring to 80 ±5℃;
(3) water phase in step (1) in water phase pot is first transferred to emulsion pot, then by the oil in phase pot oily in step (2) It is mutually pumped into emulsion pot, vacuumizes -0.02MPa to -0.05MPa, open stirring 50Hz-60Hz, homogeneous rate 2000rpm- 3000rpm, homogeneous 10-15 minutes, insulated and stirred 10-15 minutes after homogeneous;
(4) start to cool down after keeping the temperature, when being cooled to 50 DEG C or less, be proportionally added into lightening compositions, skin condition Agent, penetration-assisting agent, essence and presumable low temperature addition use preservative, continue after mixing evenly stirring be cooled to 45 DEG C hereinafter, Up to whitening brightening cream of the invention.
Wherein, mixture or single constituent be can choose when preservative generally uses, it is water-soluble to generally include high temperature The preservative that the molten preservative of preservative, high temperature oil and low temperature can dissolve, therefore, whitening brightening cream is above-mentioned in the present invention In 4 process steps of preparation, different preservative types is added according to the different stages respectively.
Preferably, moisturizer selected from propylene glycol, sorbierite, butanediol, pungent glycol, methyl propanediol, dipropylene glycol, Glycerol, diglycerol, glycerin polyether, pentanediol, isoprene, polyethylene glycol, trehalose, Sodium Hyaluronate, polyglutamic acid sodium It is one or more, it is preferred for of the invention being glycerol, butanediol and Sodium Hyaluronate.
Preferably, emulsifier selected from ceteareth -2, ceteareth -21, stearine, The smooth stearate of PEG-100 stearate, polysorbate -60, sorb, sucrose stearate, glyceryl stearate citrate, One of alkyl glycosides, cetostearyl alcohol olive oleate, the smooth olive oleate of sorb etc. are a variety of, are preferred for this hair Bright is cetostearyl alcohol olive oleate, the smooth olive oleate of sorb.
Preferably, moisturizing grease is selected from synthesis grease (caprylic/capric triglyceride, isopropyl palmitate, nutmeg Isopropyl propionate, cetanol ethylhexoate, C12-15 alcohol benzoic ether, Parleam, three isostearates, pentaerythrite Four isostearic acids, glycerol three (thylhexoic acid) ester, dicaprylyl ether, two octanoic acids of propylene glycol/dicaprate, two octanoic acid/bis- of butanediol Decylate, isononyl isononanoate etc.), natural oil (tocopherol acetate, olive oil, jojoba oil, sun flower seed oil, mustard Oil, grape seed oil, macadimia nut oil, saualane etc.), mineral grease (dormant oil, vaseline), silicone oil (dimethyl silicone polymer, poly- two Methylsiloxane alcohol, octyl dimethyl silicone polymer, ring five dimethyl silicone polymer etc.) one of or it is a variety of, be preferred for Of the invention is isononyl isononanoate, dimethyl silicone polymer, caprylic/capric triglyceride and tocopherol acetate.
Preferably, skin conditioning agent selected from SymRelief100 (bisabolol, ginger-root extract), MilleCareFE (bacillus/fermented soybean product extract, folic acid, polyglutamic acid sodium), tea extract, Europe gentian One of extracting solution is a variety of, be preferred for it is of the invention be moral fragrant SymRelief100.
Preferably, penetration-assisting agent is selected from one of Laurocapram, hydrolysis glycosaminoglycan, N-acetyl-glucosamine Or it is a variety of, it is preferred for of the invention being N-acetyl-glucosamine.
Preferably, chelating agent is selected from EDTA-2Na, parahydroxyacet-ophenone, it is preferred for of the invention being EDTA- 2Na。
Preferably, thickener is selected from carbomer, xanthan gum, SEMUGEL EG (sodium acrylate/acryloyldimethyl ox Sodium sulfonate copolymers/isohexadecane/Polyoxyethylene Sorbitan Monooleate), SEMUGEL NS (hydroxy ethyl methacrylate/acryloyldimethyl ox Sodium sulfonate copolymers/saualane/polysorbate -60), (polyacrylamide/C13-14 isoparaffin/laurel of SEPIGEL 305 Alcohol polyethers -7), SEPINOV EMT10 (hydroxyethylacrylate/sodium acryloyldimethyl taurate copolymers), SEPIPLUS265 (ammonium acrylate and acrylamide copolymer/polyisobutene/polysorbate -20), SEPIPLUS 400 are (poly- 13/ polyisobutene of acrylic acid/polysorbate -20), SIMUGEL INS100 (hydroxy ethyl methacrylate/acryloyldimethyl ox Sodium sulfonate copolymers/isohexadecane/polysorbate -60) one of or it is a variety of, be preferred for it is of the invention be xanthan gum and SEPIPLUS 400。
Preferably, preservative is selected from methyl hydroxybenzoate, Nipasol, Phenoxyethanol, decoyl hydroximic acid, 1,2 hexylene glycols One of or it is a variety of, be preferred for of the invention being methyl hydroxybenzoate and Phenoxyethanol.
The present composition may also include various other compositions.The function of the specific composition of composition of the invention It will be described below with effect.
Ginseng is known as " King of Herbs ", more and more confirmations that various effects have been subjected to.For skin Speech, ginseng can promote blood circulation because containing panaxoside, prevent skin ageing and wrinkle from generating, increase the nutrition supplying of skin The effect of answering, playing tonifying Qi beauty treatment and promoting blood circulation, while immune function can also be improved, prevent skin from receiving harmful thorn of external environment Swash.It can accelerate human metabolism, deep layer moisturizing, prevent dry and aging and effectively treatment itch and decortication, make face Skin is moist, makes skin pure white tender.
The root bark of white mulberry is a kind of relatively common Chinese medicine, there is beautifying face and moistering lotion.Flavonoid substances are rich in the root bark of white mulberry, There is significant inhibiting effect to tyrosinase, inhibit the formation of pigment, has the effect of certain nti-freckle and beauty.
Angelica extract can speed up the blood circulation of skin, boost metabolism.Pharmacological experiment study is the results show that work as Return extract that can remove the free radical in skin, delay skin aging, and is able to suppress melanin generation.
Licorice includes glycyrrhizin, glycyrrhizic acid, liquiritin, flavonoids of Glycyrrhiza, Quercetin etc., by inhibiting junket ammonia The activity of sour enzyme and dopachrome interconvertible enzyme (TRP-2), the polymerization for hindering 5,6-dihydroxy indoles (DHl) are black to prevent with this The formation of pigment, to achieve the effect that skin whitening.
The catechin component being rich in tealeaves can effectively desalinate and eliminate chloasma, and has apparent beauty functions.Youngster Theine and caffeine belong to two big important functional ingredients in tealeaves, and catechin be in tea extract it is most important at Point.Catechin rich in tea polyphenols has very strong removing free radical and oxidation resistant ability, and has significantly to color spot is eliminated Containment effect.
Black Ganoderma is " mesona " in all age, record according to Shennong's Herbal " purple sesame can control deaf, sharp joint, protect mind, Strengthening the essence gas, hard muscles and bones " has brain tonic, anti-inflammatory, diuresis, beneficial stomach, strengthening by means of tonics effect.Polysaccharide contained by ganoderma lucidum, polypeptide etc. have bright Aobvious function of delaying senility, promotion and adjustment immune function, adjust metabolic balance, promote the synthesis of nucleic acid and protein, resist certainly It is acted on by base.Ganoderma lucidum polysaccharide has significantly quasi- SOD activity, the free radical of body generation can be significantly removed, to prevent free radical Damage to body, it is therefore prevented that the peroxidating of rouge body protects cell, delayed cell ageing.
Root of kirilow rhodiola has highly important medical value, it is recorded in Compendium of Material Medica, which mainly has, " strengthens the body resistance to consolidate the constitution, tonifying Qi is supported The effect of blood, clearing heat and moistening lung ", referred to as " snow mountain mesona " and " plateau ginseng ".Root of kirilow rhodiola can improve body with delaying cell aging The activity of interior SOD inhibits the formation of cell lipofuscin and free radical.The metabolism and synthesis for enhancing cell, improve the work of cell Power also has the effect of beauty care.
Ginkgo leaf nature and flavor sweetness and bitterness is puckery flat, there is invigorating heart astringing lung-QI, dampness elimination antidiarrheal and other effects." Chinese medicinal herbal " record it can " astringing lung-QI gas, It relievings asthma cough, check with turbidity ".According to modern pharmacological research, ginkgo leaf is relatively broad to the effect of human body and animal body, such as improves cardiovascular And peripheral vessels circulatory function, there is improvement result to myocardial ischemia, has the function of promoting memory, improves brain function.In addition, Blood viscosity can also be reduced, remove free radical.By reducing level of lipid, freckle, moist skin, beautiful appearance are reduced.
The beneficial effects of the present invention are:
1. the present invention uses compounded formula, using natural plant extracts, reach mild effective whitening skin lightening Effect, avoids the cytotoxicity of traditional whitening agent, while reducing skin irritatin.
2. in the present invention, Trenaxmine is able to suppress tyrosinase activity, to inhibit melanin production;Niacinamide can add Fast melanin metabolism, and melanin is prevented to shift to epidermis, to reduce melanin in the calmness of skin, both chemistry at Divide has collaboration whitening function together with natural plant extracts, reaches healthy effective whitening skin lightening result.
3. the present invention is arranged in pairs or groups using reasonable emulsifier and grease, thus while having good whitening skin lightening effect, tool There is use feeling that is moist, not sticky, easily absorbing.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention, Technical solution of the present invention is clearly and completely described, it is clear that described embodiment is that a part of the invention is implemented Example, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making creativeness Every other embodiment obtained, shall fall within the protection scope of the present invention under the premise of labour.
Embodiment 1:
The present embodiment provides a kind of whitening brightening cream comprising lightening compositions, it includes lightening compositions, including it is following The each component of parts by weight: 1 part of ginseng extracting solution, 1 part of root bark of white mulberry extracting solution, 1 part of angelica root extracting solution, 1 part Grass roots extracting solution, 1 part of tea extract, 1 part of Black Ganoderma extracting solution, 1 part of ginkgo biloba succi, 1 part of root of Rhodiola sachalinensis Extracting solution, 3 parts of niacinamide, 1 part of Trenaxmine are named as lightening compositions I.
The present embodiment also provides a kind of whitening brightening cream comprising lightening compositions, each group comprising following mass percent Point: 5% lightening compositions I, 5% butanediol, 2% glycerol, 3% propylene glycol, 2.5% cetostearyl alcohol olive oleate, 1% The smooth olive oleate of sorb, 5% isononyl isononanoate, 1% dimethyl silicone polymer, 2% caprylic/capric triglyceride, 0.5% Tocopherol acetate, 0.15%SymRelief100,2%N- acetylglucosamine, 0.05%EDTA-2Na, 0.1% xanthan gum, 0.5%SEPIPLUS 400,0.15% essence, 0.2% methyl esters, 0.4% Phenoxyethanol, surplus are deionized water.
The refreshing preparation method of the whitening skin lightening the following steps are included:
(1) deionized water, glycerol, butanediol, propylene glycol, methyl esters, EDTA-2Na, xanthan gum, SEPIPLUS 400 are added Enter water phase pot, is heated with stirring to 90 DEG C;
(2) by cetostearyl alcohol olive oleate, the smooth olive oleate of sorb, isononyl isononanoate, polydimethylsiloxanes Oily phase pot is added in alkane, caprylic/capric triglyceride, tocopherol acetate, is heated with stirring to 80 DEG C;
(3) water phase pot material is transferred to emulsion pot, then oil phase material is pumped into, and vacuumizes -0.02MPa, opens stirring 50Hz, Homogeneous rate 2000rpm, homogeneous 10 minutes, insulated and stirred 10 minutes after homogeneous;
(4) start to cool down after keeping the temperature, when being cooled to 50 DEG C or less, addition lightening compositions I, SymRelief100, N-acetyl-glucosamine, essence and Phenoxyethanol continue stirring after mixing evenly and are cooled to 45 DEG C hereinafter, i.e. Obtain whitening brightening cream of the invention.
Embodiment 2:
The present embodiment provides a kind of whitening brightening cream comprising lightening compositions, it includes lightening compositions, including it is following The each component of parts by weight: 1 part of ginseng extracting solution, 2 parts of root bark of white mulberry extracting solution, 2 parts of angelica root extracting solution, 1 part Licorice extracting solution, 2 parts of tea extract, 1 part of Black Ganoderma extracting solution, 2 parts of ginkgo biloba succi, 1 part of root of kirilow rhodiola Root extracting solution, 3 parts of niacinamide, 1 part of Trenaxmine are named as lightening compositions II.
The present embodiment also provides a kind of whitening brightening cream comprising lightening compositions, each group comprising following mass percent Point: 5% lightening compositions II, 5% butanediol, 2% glycerol, 3% propylene glycol, 2.5% cetostearyl alcohol olive oleate, The smooth olive oleate of 1% sorb, 5% isononyl isononanoate, 1% dimethyl silicone polymer, 2% caprylic/capric triglyceride, 0.5% tocopherol acetate, 0.15%SymRelief100,2%N- acetylglucosamine, 0.05%EDTA-2Na, 0.1% Chinese are raw Glue, 0.5%SEPIPLUS 400,0.15% essence, 0.2% methyl esters, 0.4% Phenoxyethanol, surplus are deionized water.
The refreshing preparation method of the whitening skin lightening the following steps are included:
(1) deionized water, glycerol, butanediol, propylene glycol, methyl esters, EDTA-2Na, xanthan gum, SEPIPLUS 400 are added Enter water phase pot, is heated with stirring to 90 DEG C;
(2) by cetostearyl alcohol olive oleate, the smooth olive oleate of sorb, isononyl isononanoate, polydimethylsiloxanes Oily phase pot is added in alkane, caprylic/capric triglyceride, tocopherol acetate, is heated with stirring to 80 DEG C;
(3) water phase pot material is transferred to emulsion pot, then oil phase material is pumped into, vacuumize -0.02MPa, open stirring 50HzHz, homogeneous rate 2000rpmrpm, homogeneous 10 minutes, insulated and stirred 10 minutes after homogeneous;
(4) start to cool down after keeping the temperature, when being cooled to 50 DEG C or less, addition lightening compositions II, SymRelief100, N-acetyl-glucosamine, essence and Phenoxyethanol continue stirring after mixing evenly and are cooled to 45 DEG C hereinafter, i.e. Obtain whitening brightening cream of the invention.
Embodiment 3:
The present embodiment provides a kind of whitening brightening cream comprising lightening compositions, it includes lightening compositions, including it is following The each component of parts by weight: 2 parts of ginseng extracting solution, 5 parts of root bark of white mulberry extracting solution, 1 part of angelica root extracting solution, 3 parts Grass roots extracting solution, 2 parts of tea extract, 1 part of Black Ganoderma extracting solution, 1 part of ginkgo biloba succi, 2 parts of root of Rhodiola sachalinensis Extracting solution, 3 parts of niacinamide, 2 parts of Trenaxmine are named as lightening compositions III.
The present embodiment also provides a kind of whitening brightening cream comprising lightening compositions, each group comprising following mass percent Point: 5% lightening compositions III, 5% butanediol, 2% glycerol, 5% propylene glycol, 3% cetostearyl alcohol olive oleate, The smooth olive oleate of 0.5% sorb, 4% cetanol ethylhexoate, 1.5% dimethyl silicone polymer, 3% caprylic/capric are sweet Oily three esters, 0.5% tocopherol acetate, 0.15%SymRelief 100,2%N- acetylglucosamine, 0.05%EDTA-2Na, 0.1% xanthan gum, 0.5%SEPIPLUS 400,0.15% essence, 0.2% methyl esters, 0.4% Phenoxyethanol, surplus are deionization Water.
The refreshing preparation method of the whitening skin lightening the following steps are included:
(1) by deionized water, glycerol, butanediol, propylene glycol, methyl esters, EDTA-2Na, 0.1% xanthan gum, 0.5% Water phase pot is added in SEPIPLUS 400, is heated with stirring to 95 DEG C;
(2) by cetostearyl alcohol olive oleate, the smooth olive oleate of sorb, cetanol ethylhexoate, poly dimethyl Oily phase pot is added in siloxanes, caprylic/capric triglyceride, tocopherol acetate, SymRelief 100, is heated with stirring to 85 DEG C;
(3) water phase pot material is transferred to emulsion pot, then oil phase material is pumped into, vacuumize -0.05MPa, open stirring 60Hz, homogeneous rate 3000rpm, homogeneous 15 minutes, insulated and stirred 15 minutes after homogeneous;
(4) start to cool down after keeping the temperature, when being cooled to 50 DEG C or less, addition lightening compositions III, SymRelief100, N-acetyl-glucosamine, essence and Phenoxyethanol continue stirring after mixing evenly and are cooled to 45 DEG C hereinafter, i.e. Obtain whitening brightening cream of the invention.
Embodiment 4:
The present embodiment provides a kind of the whitening brightening cream comprising lightening compositions, each group comprising following mass percent Point: 10% lightening compositions III, 5% butanediol, 2% glycerol, 2% propylene glycol, 1.5% ceteareth -2,2.5% Ceteareth -21,4% cetanol ethylhexoate, 1.5% dimethyl silicone polymer, 2% olive oil, 1.5% spermaceti Stearyl alcohol, 0.5% tocopherol acetate, 0.15%SymRelief 100,2%N- acetylglucosamine, 0.05%EDTA-2Na, 0.1% xanthan gum, 0.5%SEPIPLUS 400,0.15% essence, 0.2% methyl esters, 0.4% Phenoxyethanol, surplus are deionization Water.
The refreshing preparation method of the whitening skin lightening the following steps are included:
(1) deionized water, glycerol, butanediol, propylene glycol, methyl esters, EDTA-2Na, xanthan gum, SEPIPLUS 400 are added Enter water phase pot, is heated with stirring to 85 DEG C;
(2) by ceteareth -2, ceteareth -21, cetanol ethylhexoate, polydimethylsiloxanes Oily phase pot is added in alkane, olive oil, cetostearyl alcohol, tocopherol acetate, is heated with stirring to 75 DEG C;
(3) water phase pot material is transferred to emulsion pot, then oil phase material is pumped into, vacuumize -0.04MPa, open stirring 55Hz, homogeneous rate 2500rpm, homogeneous 12 minutes, insulated and stirred 12 minutes after homogeneous;
(4) start to cool down after keeping the temperature, when being cooled to 50 DEG C or less, lightening compositions III, SymRelief are added 100, N-acetyl-glucosamine, essence and Phenoxyethanol continue stirring after mixing evenly and are cooled to 45 DEG C hereinafter, up to of the invention Whitening brightening cream.
Embodiment 5:
The present embodiment provides a kind of whitening brightening cream comprising lightening compositions, it includes lightening compositions, including it is following The each component of parts by weight: 0.1 part of ginseng extracting solution, 10 parts of root bark of white mulberry extracting solution, 0.1 part of angelica root extracting solution, 10 parts of grass roots extracting solution, 0.1 part of tea extract, 10 parts of Black Ganoderma extracting solution, 0.1 part of niacinamide, 10 parts of biography Bright acid is named as lightening compositions IV.
The present embodiment also provides a kind of whitening brightening cream comprising lightening compositions, each group comprising following mass percent Point: 20% lightening compositions IV, 25% butanediol, 5% ceteareth -2,10% Parleam, 10% 2 Octyl Ether, 5% tea extract, 3% Laurocapram, 1% parahydroxyacet-ophenone, 1% xanthan gum, 1% essence, 2%1,2 oneself Glycol, surplus are deionized water.
Embodiment 6:
The present embodiment provides a kind of whitening brightening cream comprising lightening compositions, it includes lightening compositions, including it is following The each component of parts by weight: 10 parts of ginseng extracting solution, 0.1 part of root bark of white mulberry extracting solution, 10 parts of angelica root extracting solution, 0.1 part of grass roots extracting solution, 10 parts of tea extract, 0.1 part of Black Ganoderma extracting solution, 0.1 part of ginkgo biloba succi, 10 Root of Rhodiola sachalinensis extracting solution, 10 parts of the niacinamide, 0.1 part of Trenaxmine of part, are named as lightening compositions V.
The present embodiment also provides a kind of whitening brightening cream comprising lightening compositions, each group comprising following mass percent Point: 1% lightening compositions III, 5% glycerol, 2% polysorbate -60,2.5% isopropyl myristate, 2.5% Ji Wusi Four isostearic acid of alcohol, 0.1%MilleCare FE, 0.05% hydrolysis glycosaminoglycan, 0.01% parahydroxyacet-ophenone, 0.1% carbomer, 0.05% essence, 0.05% methyl esters, surplus are deionized water.
Embodiment 7:
The present embodiment provides a kind of whitening brightening cream comprising lightening compositions, it includes lightening compositions, including it is following The each component of parts by weight: 2 parts of ginseng extracting solution, 2 parts of root bark of white mulberry extracting solution, 5 parts of angelica root extracting solution, 5 parts Grass roots extracting solution, 2 parts of tea extract, 5 parts of Black Ganoderma extracting solution, 5 parts of ginkgo biloba succi, 2 parts of root of Rhodiola sachalinensis Extracting solution, 2 parts of niacinamide, 5 parts of Trenaxmine are named as lightening compositions VI.
The present embodiment also provides a kind of whitening brightening cream comprising lightening compositions, each group comprising following mass percent Point: 10% lightening compositions VI, 10% glycerol, 1% polysorbate -60,5% isopropyl myristate, 5% pentaerythrite Four isostearic acids, 2%MilleCare FE, 1% hydrolysis glycosaminoglycan, 0.5% parahydroxyacet-ophenone, 0.5% carbomer, 1%1,2 hexylene glycols, surplus are deionized water.
In order to verify the whitening skin lightening result of the above various embodiments of the present invention, reducing irritation and moisten not sticky easy suction The characteristics of receipts, spy take following means of testing:
The test of whitening skin lightening result:
Test foundation: group norms T/ZHCA001-2018 cosmetics whitening effect test method.
Test crowd: meet human skin patch subject selection in " cosmetics safety technical specification " 2015 editions and want It asks, it is all women that number, which adds up to 30 people, and age bracket 25-45 years old, average age 36 years old.
Testing time and place: 2018.11.10-2018.12.31, Shanghai, testing time are winter, it is ensured that test position It is wrapped in clothes, is not affected by the external environment.
Test position and requirement: on the inside of the left forearm for selecting tester, 30 bit test persons select same position, during test Forbid taking orally, inject or smearing other whitening medicaments or Related product, test position forbids being exposed to the sun, except taking a shower it daily It is not crumpled excessively when no longer cleaning test zone outside, and taking a shower.
Test product: 1# product is 1 gained cream of the embodiment of the present invention;2# product is 2 gained cream of the embodiment of the present invention; 3# product is that control group removes lightening compositions I, supplemented with deionized water referring to the component of the embodiment of the present invention 1, identical reality It applies obtained by mode.
Test equipment: MPA4 (Multi Probe Adapter) system of German CK company selects Colorimeter CL400 (skin color test) probe.
Test method: three test zones, each region area delimited in the same position on the inside of selection subject's left forearm For 2.0cm*2.0cm, with marking pen marked region boundary and zone number, number difference 1-3 is corresponded to and is used product 1#-3#.It takes Appropriate product daily respectively smear once in test zone sooner or later by (after washing one's face and rinsing one's mouth), smears uniformly complete to absorbing.Start in test Be calculated as D0 within first day, with Colorimeter CL400 probe measurement skin color data, the then skin of measurement in every 7 days Color data, test period are 28 days, i.e. measurement five groups of data of D0, D7, D14, D21, D28.
Test data processing: with Colorimeter CL400 probe respectively measure skin three primary colours values L*, a*, B* calculates ITA °, i.e. skin whiteness value by ITA °=[ArcTan (L*-50)/b*] × 180/ π of formula.ITA ° of value is bigger, Indicate that skin complexion is more shallow.L* indicates the brightness of skin, and b* indicates the coloration of skin.Respectively measure 30 subjects L*, a*, B* value acquires its average and calculates ITA ° of value again.
Test result such as table 1- table 3:
Table 1: L* value, a* value, b* value and the I TA ° value of test position 1
Table 2: L* value, a* value, b* value and the I TA ° value of test position 2
Table 3: L* value, a* value, b* value and the I TA ° value of test position 3
Test result: by 3 measurement data of table 1- table it is found that using 1# product and after 2# product 28 days, skin whiteness value is bright Aobvious to increase, increasing degree is 80% or so, and control group has almost no change.L* value represents the brightness of skin, by test data It is found that skin brightness value is significantly improved, and control group skin brightness is almost without change using 1# product and after 2# product 28 days Change.It follows that whitening brightening cream of the invention has significant whitening skin lightening effect.
Have effects that reduce irritation to verify lightening compositions of the invention, spy is tested as follows:
Experimental basis and method: the test of group norms T/SHRH 011-2018 chick chorioallantoic membrane, according to the standard side Method carries out irritation test, determine and records ES value.
Laboratory apparatus and object: stereomicroscope, candler, incubator, microsyringe, physiological saline, tweezers, experiment Object is SPF grades of white Leghorns fertilization chicken embryos.
Test product: 1# product is 1 gained cream of the embodiment of the present invention;2# product is 2 gained cream of the embodiment of the present invention; 4# product is that control group removes eight Plant Extracts in lightening compositions I, use deionized water referring to the embodiment of the present invention 1 Supplement, identical embodiment gained.
Test data processing: the degree melted according to the bleeding, blood coagulation and blood vessel that occur on CAM film gives 0,1 respectively, 2,3 points of evaluations calculate ES mean scores according to following formula:
Evaluation criterion: evaluation criterion such as table 4:
Table 4:ES value corresponds to irritation evaluation criterion
Terminal scoring Irritation classification
ES≤12 Nothing/subexcite
12<ES<16 Moderate irritation
ES≥16 Serious irritation
Test result: test result such as table 5:
Table 5: sample CAM film irritation test result
Sample Terminal scoring Irritation classification
1# product 8.52 Nothing/subexcite
2# product 7.65 Nothing/subexcite
4# product 12.25 Moderate irritation
Test result evaluation: according to test result, the 1# and 2# of plant extraction liquid in lightening compositions of the present invention are added to The irritation of sample, hence it is evident that it is lower than the 4# product of control group, reduce the irritation of integral formula, reduction irritation of the invention Effect obtains good validation.
There is the moist not sticky characteristic easily absorbed in order to verify whitening brightening cream of the invention, carried out following test:
Test method: 20 subjects, age requirement 25-45 years old, daily habits used cosmetics crowd.To 20 before test Position subject does simple training, main to explain moist cream, sticky and absorbability evaluation criterion and score basis.Moistness root According to 1-10 points of moist degree scoring, score is higher, indicates that moistness is better.Sticky sense is scored 1-10 points according to sticky degree, point Number is higher, indicates more sticky.For absorbability according to 1-10 points of degree of absorption scoring easy when smearing, score is higher, indicates that absorbability is got over It is good.
Test position: test position is the cheek position of subject.
Test product: 1# product is 1 gained cream of the embodiment of the present invention;2# product is 2 gained cream of the embodiment of the present invention.
Test result: test result such as table 6:
Table 6: skin senses test result
Test result evaluation: according to test test result it is found that application example of the invention has moisture feeling good, sticky sense Characteristic that is low, easily absorbing.
In order to verify the whitening safety of whitening brightening cream of the invention, has been done to 2 gained cream of the embodiment of the present invention Tripartite's detection, according to " cosmetics safety technical specification " 2015 editions requirement, the project that predominantly detects is nine conventional (heavy metal, micro- Biology) it is detected plus acrylamide, dioxanes, testing result such as table 7:
Table 7: Product Safety testing result
Evaluation: as seen from table, whitening brightening cream of the invention complies fully with " cosmetics safety technical specification " 2015 editions requirements, have good safety.
In conclusion a kind of whitening brightening cream skin sense comprising lightening compositions disclosed by the invention is moistened without sticky, It easily absorbs, whitening skin lightening result is significant.Wherein lightening compositions have collaboration whitening and reduce irritation effect.
It is provided for the embodiments of the invention technical solution above to be described in detail, specific example used herein The principle and embodiment of the embodiment of the present invention are expounded, the original for helping to understand the embodiment of the present invention is only applicable to Reason, is not intended to limit the invention, any modification, equivalent substitution and improvement done within the spirit and principles of the present invention Deng should all be included in the protection scope of the present invention.

Claims (9)

1. a kind of lightening compositions, which is characterized in that the lightening compositions comprise the following components in parts by weight: 0.1-10 parts Ginseng extracting solution, 0.1-10 parts of root bark of white mulberry extracting solution, 0.1-10 parts of angelica root extracting solution, 0.1-10 parts of licorice mention Take liquid, 0.1-10 parts of tea extract, 0.1-10 parts of Black Ganoderma extracting solution, 0.5-10 parts of niacinamide and 0.1-10 part Trenaxmine.
2. lightening compositions according to claim 1, which is characterized in that the lightening compositions further include following parts by weight Component: 0.1-10 parts of ginkgo biloba succi, 0.1-10 parts of root of Rhodiola sachalinensis extracting solution.
3. lightening compositions according to claim 2, which is characterized in that the lightening compositions include following parts by weight Component: 2-5 parts of ginseng extracting solution, 2-5 parts of root bark of white mulberry extracting solution, 2-5 parts of angelica root extracting solution, 2-5 parts of Radix Glycyrrhizae Root extracting solution, 2-5 parts of tea extract, 2-5 parts of Black Ganoderma extracting solution, 2-5 parts of ginkgo biloba succi, 2-5 parts red Red-spotted stonecrop root extracting solution, 2-5 parts of niacinamide and 2-5 parts of Trenaxmine.
4. a kind of preparation method of lightening compositions, which is characterized in that including the following steps:
Step 1: prepare ginseng extracting solution, root bark of white mulberry extracting solution, angelica root extracting solution, licorice extracting solution, tealeaves and extract Liquid, Black Ganoderma extracting solution, ginkgo biloba succi, root of Rhodiola sachalinensis extracting solution, niacinamide and Trenaxmine;
Step 2: according to parts by weight require: 0.1-10 parts of ginseng extracting solution, 0.1-10 parts of root bark of white mulberry extracting solution, 0.1-10 parts of angelica root extracting solution, 0.1-10 parts of licorice extracting solution, 0.1-10 parts of tea extract, 0.1-10 parts Black Ganoderma extracting solution, 0.5-10 parts of niacinamide and 0.1-10 parts of Trenaxmine, each component is weighed and is mixed, stir It mixes uniformly to obtain the final product.
5. a kind of whitening brightening cream comprising lightening compositions described in any one of claims 1 to 3, which is characterized in that Component including following mass percent meter: 0.1%-20% lightening compositions, 1%-25% moisturizer, 1%-5% emulsifier, 1%-20% moisturizing grease, 0.1%-5% skin conditioning agent, 0.05%-3% penetration-assisting agent, 0.01%-1% chelating agent, 0.1%- 1% thickener, 0%-1% essence and 0.05%-2% preservative, surplus are deionized water.
6. the whitening brightening cream according to claim 5 comprising lightening compositions, which is characterized in that including following quality hundred Divide the component than meter: 1%-20% lightening compositions, 5%-25% moisturizer, 2%-5% emulsifier, 5%-20% soothing oil Rouge, 0.1%-5% skin conditioning agent, 0.05%-3% penetration-assisting agent, 0.01%-1% chelating agent, 0.1%-1% thickener, 0.05%-1% essence and 0.05%-2% preservative, surplus are deionized water.
7. the whitening brightening cream according to claim 5 or 6 comprising lightening compositions, which is characterized in that the moisturizer Selected from propylene glycol, sorbierite, butanediol, pungent glycol, methyl propanediol, dipropylene glycol, glycerol, diglycerol, glycerin polyether, penta Glycol, isoprene, polyethylene glycol, trehalose, Sodium Hyaluronate, polyglutamic acid sodium it is one or more;
The emulsifier is hard selected from ceteareth -2, ceteareth -21, stearine, PEG-100 The smooth stearate of resin acid ester, polysorbate -60, sorb, sucrose stearate, glyceryl stearate citrate, alkyl glycosides One of class, cetostearyl alcohol olive oleate, the smooth olive oleate of sorb etc. are a variety of;
The moisturizing grease is selected from one of synthesis grease, natural oil, mineral grease, silicone oil or a variety of;
The skin conditioning agent is in SymRelief100, MilleCare FE, tea extract, Europe gentian extracting solution It is one or more;
The penetration-assisting agent is selected from one of Laurocapram, hydrolysis glycosaminoglycan, N-acetyl-glucosamine or a variety of;
The chelating agent is selected from one of EDTA-2Na, parahydroxyacet-ophenone or a variety of;
The thickener is selected from carbomer, xanthan gum, SEMUGEL EG, SEMUGEL NS, SEPIGEL 305, SEPINOV One of EMT10, SEPIPLUS 265, SEPIPLUS 400, SIMUGEL INS100 or a variety of;
The preservative be selected from methyl hydroxybenzoate, Nipasol, Phenoxyethanol, decoyl hydroximic acid, 1, one of 2 hexylene glycols or It is a variety of.
8. the whitening brightening cream according to claim 7 comprising lightening compositions, which is characterized in that
The moisturizer is one of glycerol, butanediol and Sodium Hyaluronate or a variety of;
The emulsifier is one of cetostearyl alcohol olive oleate, the smooth olive oleate of sorb or a variety of;
The moisturizing grease is isononyl isononanoate, dimethyl silicone polymer, caprylic/capric triglyceride and tocopherol acetate It is one or more;
The skin conditioning agent is SymRelief100;
The penetration-assisting agent is N-acetyl-glucosamine;
The chelating agent is EDTA-2Na;
The thickener is xanthan gum or SEPIPLUS 400;
The preservative is methyl hydroxybenzoate or Phenoxyethanol.
9. a kind of preparation method of the whitening brightening cream comprising lightening compositions, which is characterized in that comprise the steps of:
(1) water phase pot is added in deionized water, moisturizer, chelating agent, thickener and presumable high temperature Water-soluble preservatives, stirred It mixes and is heated to 90 ± 5 DEG C;
(2) oily phase pot is added in moisturizing grease, emulsifier and the molten preservative of presumable high temperature oil, is heated with stirring to 80 ± 5 ℃;
(3) water phase in water phase pot is first transferred to emulsion pot, then the oil in oily phase pot is mutually pumped into emulsion pot, vacuumize- 0.02MPa to -0.05MPa is opened and is stirred 50Hz-60Hz, homogeneous rate 2000rpm-3000rpm, and homogeneous 10-15 minutes, homogeneous After insulated and stirred 10-15 minutes;
(4) keep the temperature after start to cool down, when being cooled to 50 DEG C or less, addition lightening compositions, skin conditioning agent, penetration-assisting agent, Essence and presumable low temperature add preservative, continue stirring after mixing evenly and are cooled to 45 DEG C hereinafter, up to beauty of the invention White brightening cream.
CN201910064750.8A 2019-01-23 2019-01-23 Lightening compositions, whitening brightening cream comprising lightening compositions and preparation method thereof Pending CN109528603A (en)

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Cited By (12)

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Publication number Priority date Publication date Assignee Title
CN110917069B (en) * 2019-12-27 2022-10-21 杭州菲丝凯化妆品有限公司 Anti-incipient-aging whitening moisturizing and repairing face cream and preparation method thereof
CN110917069A (en) * 2019-12-27 2020-03-27 杭州菲丝凯化妆品有限公司 Anti-incipient-aging whitening moisturizing and repairing face cream and preparation method thereof
CN112315845A (en) * 2020-12-03 2021-02-05 广东嘉丹婷日用品有限公司 Whitening and freckle removing cream and preparation method thereof
CN112516054A (en) * 2020-12-30 2021-03-19 福建臻昕美生物科技有限公司 Tea polyphenol protein cream for repairing, moisturizing and strengthening skin and production process thereof
CN112891277A (en) * 2021-03-06 2021-06-04 圣美(深圳)环球科技有限公司 Whitening anti-allergy anti-wrinkle cream and preparation method thereof
CN112891278A (en) * 2021-03-19 2021-06-04 河南董欣生物科技有限公司 Whitening composition, preparation method and application
CN112891278B (en) * 2021-03-19 2023-03-07 河南董欣生物科技有限公司 Whitening composition, preparation method and application
CN113440468A (en) * 2021-08-17 2021-09-28 徐晓英 Skin conditioner compound for whitening and brightening skin, novel skin cream and preparation method thereof
CN113693993A (en) * 2021-10-16 2021-11-26 江西广恩和药业股份有限公司 Foot beautifying cream and preparation method thereof
CN113768847A (en) * 2021-10-29 2021-12-10 广州珈纳生物科技有限公司 Face cream for brightening skin color and preparation method thereof
CN115487123A (en) * 2021-11-09 2022-12-20 上海丽舒丹医药科技有限公司 Mild whitening composition containing plant polyphenol and application thereof
CN115177551A (en) * 2022-08-19 2022-10-14 广州陶妆生物科技有限公司 Cosmetic additive
CN115813839A (en) * 2022-12-16 2023-03-21 蓝音(兰州)生物科技有限公司 Traditional Chinese medicine cosmetic composition for moisturizing, resisting aging and brightening skin and preparation method thereof
CN117838606A (en) * 2023-12-26 2024-04-09 天地慈(东莞)生物科技有限公司 Whitening and brightening composition and preparation method thereof
CN117838606B (en) * 2023-12-26 2024-08-06 天地慈(东莞)生物科技有限公司 Whitening and brightening composition and preparation method thereof

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Application publication date: 20190329