CN111700850B

CN111700850B - Freckle-removing mask and preparation method thereof

Info

Publication number: CN111700850B
Application number: CN202010779798.XA
Authority: CN
Inventors: 不公告发明人
Original assignee: Meijianji Bioengineering Technology Guangzhou Co ltd
Current assignee: Meijianji bioengineering technology (Guangzhou) Co.,Ltd.
Priority date: 2020-08-05
Filing date: 2020-08-05
Publication date: 2021-04-02
Anticipated expiration: 2040-08-05
Also published as: CN111700850A

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to a freckle-removing mask and a preparation method thereof, wherein the freckle-removing mask comprises the following components in parts by weight: emulsifier, humectant, emollient, thickener, stabilizer, birch bark extract, Alpinia katsumadai seed extract, edelweiss extract, niacinamide, and deionized water; the stabilizer consists of a polished round-grained rice extract and a vernalia extract. The spot removing mask disclosed by the invention is scientific and reasonable in overall formula matching, the japonica rice extract and the vernal flower extract which are prepared by a special process are creatively adopted to be cooperated as a stabilizer, the temperature tolerance of the spot removing mask is obviously improved, the spot removing mask has excellent low-temperature stability and high-temperature stability, and whitening components can effectively reach the skin bottom directly, so that spots are lightened and yellow are removed, and the skin is full and has high gloss.

Description

Freckle-removing mask and preparation method thereof

Technical Field

The invention belongs to the technical field of cosmetics, and particularly relates to a freckle-removing mask and a preparation method thereof.

Background

The stain includes freckle, black spot, chloasma and senile plaque, and belongs to pigmentation disorder dermatosis. The pigmented spots are a common skin disease with brown or melanotic, disfiguring appearance on the face due to the increase of melanin in the skin, and are frequently found in the cheek and forehead. The main causes of color spots are: melanocyte of human body is located in basal layer of epidermis, mainly responsible for protecting new born cell from ultraviolet ray, melanocyte and basal cell are stored in basal layer, the ratio of them is about 1:10, melanocyte can absorb tyrosine, tyrosine enters into cell, and is converted into dopa under the action of tyrosine hydroxylase, and is oxidized into dopaquinone, dopachrome, finally melanin is formed, and is polymerized into melanin granules, after melanin granules are increased gradually, the activity of tyrosinase begins to be reduced gradually, melanin granules are gradually formed into melanin granules, stored in dendritic papilla, phagocytosed by epidermal basal layer macrophage, and then gradually pushed to epidermis to reach stratum corneum, and then stratum corneum also begins to appear melanin granules.

With the continuous improvement of the living standard of people, the demand of people on health care skin care products is also continuously improved, people of different ages pay attention to skin care and beauty treatment, and at present, a plurality of spot-lightening, spot-removing and whitening products appear on the market, including various whitening masks, spot-removing mask solutions, essences, whitening creams and the like.

Patent document CN106038386B discloses a composition with whitening effect, its preparation method and application, the composition mainly comprises edelweiss extract, arbutin, tranexamic acid, glabridin, propylene glycol and methylparaben, and has effects of whitening skin, removing speckle, improving skin moisturizing ability, and improving skin elasticity.

Patent document CN108524433A discloses a natural fermented moisturizing and freckle removing facial mask liquid cream special for pregnant women, which is prepared from the following raw materials: rice, millet, egg, corn stigma, dried Chinese cabbage, Poria, fructus Amomi, lactobacillus, and baker's yeast; the special natural fermented moisturizing and freckle-removing mask liquid cream for pregnant women is natural and healthy, is rich in micromolecular nutritional ingredients, is easy to absorb, is beneficial to cleaning pores, enhances the resistance of skin, avoids pigmentation, avoids the generation of cyasma, and keeps the skin moist, white and elastic; firstly, rice and millet are mixed and crushed, and the added rice is fresh polished round-grained rice which is not hulled, so that the nutrition is balanced, the contents of B vitamins, nicotine, vitamin E and amino acid are increased, the nutrition is balanced, the rice is natural and healthy, and the absorption is promoted; the corn stigma, the dry Chinese cabbage, the poria cocos and the fructus amomi are mixed and crushed and then added, so that skin color spots are reduced, absorption of nutrient components is facilitated, miscarriage prevention is facilitated, and growth and development of a fetus are promoted.

However, in the transportation or storage process of the currently marketed facial mask, the facial mask liquid is easily turbid and easily delaminated due to external factors with high or low temperature, and the quality is seriously affected, so that research and development of a freckle removing facial mask which can effectively remove freckles, whiten and brighten skin and has high stability are still problems to be solved at present.

Disclosure of Invention

Aiming at the defects in the prior art, one of the purposes of the invention is to provide the freckle-removing facial mask which is mild in formula, non-irritating, excellent in low-temperature stability and high-temperature stability, enables whitening components to effectively reach the bottom of the skin, fades spots and removes yellow, enables the skin to be full and highlight, and keeps the skin moist for a long time.

The above object of the present invention is achieved by the following technical solutions: the freckle-removing mask comprises the following components in parts by weight: 2-6 parts of an emulsifier, 6-10 parts of a humectant, 5-8 parts of an emollient, 0.1-0.2 part of a thickener, 1-3 parts of a stabilizer, 1-6 parts of an Asian white birch bark extract, 1-5 parts of an alpinia katsumadai seed extract, 1-3 parts of a edelweiss extract, 1-2 parts of nicotinamide and 65-75 parts of deionized water; the stabilizer comprises 3-5 parts of polished round-grained rice extract and 1-3 parts of veronica pubescens extract.

The vernonia pubescens extract has the effects of clearing heat and removing toxicity, calming the liver to stop wind, relieving cough, stopping bleeding, removing nebula and the like, is used for treating symptoms such as infantile hyperpyrexia convulsion, lung heat cough, hemoptysis, pertussis, mania, poisonous snake bite, conjunctival congestion and conjunctivitis and the like in folk, and is not used as a cosmetic stabilizer.

The japonica rice extract mainly contains carbohydrate, protein and B vitamins, has the effects of nourishing yin, promoting the production of body fluid, relieving restlessness, quenching thirst, strengthening spleen and stomach, and tonifying lung qi, can improve skin, keep skin smooth and white, and enable skin to have good elasticity, and is not used as a cosmetic stabilizer.

In early experiments, the freckle-removing facial mask disclosed by the invention is found to have poor low-temperature and high-temperature stability, and presumably, the reason is that certain temperature-sensitive components in the facial mask liquid are decomposed to cause the freckle-removing facial mask liquid to be easily thinned, so that more serious oil phase and water phase are separated to easily generate layering, and the product quality is seriously influenced. The inventor finds that the vernalia pubescens extract and the polished round-grained rice extract prepared by a special process are added into the mask as the stabilizer, so that the phenomena of thinning and layering of the freckle-removing mask liquid can be remarkably reduced, and the stability of the freckle-removing mask liquid is improved. On the other hand, if only one of the two stabilizers is used, the same technical effect cannot be obtained. The inventors have studied the mechanism of the above effect, and speculated that it is more likely that the vernalia pubescens extract and the japonica rice extract interact with each other to form the effect of the stable component.

The pH regulator can be added into the freckle-removing facial mask, so that the pH value of the freckle-removing facial mask is close to the pH value of facial skin, and the acid-base balance of skin cells of the freckle-removing facial mask is not easily damaged.

The Asian birch bark extract can inhibit the release of histamine, has the anti-allergy effect, has the inhibition effect on elastase and metalloproteinase, has strong anti-aging effect, and is used for conditioning skin, smoothing skin, preventing chap and improving skin color by being matched with other components.

The alpinia katsumadai seed extract is prepared from the dried nearly mature seeds of alpinia katsumadai of Zingiberaceae, and has the functions of improving the barrier function of skin, resisting aging and whitening.

The essential components of the edelweiss extract disclosed by the invention contain rich mineral substances, have the effects of relieving, calming, whitening and nourishing and protecting the skin, have an excellent effect on resisting skin aging, can mildly and deeply clean the skin, remove grease on the epidermis and substances in pores, and relieve the skin tension, and are soft and not tight.

According to the invention, the effective components of the compound are the compound of the birch bark extract, the alpinia katsumadai seed extract, the edelweiss extract and the nicotinamide, so that the effects of effectively improving skin darkness, eliminating color spots, whitening and resisting oxidation, moisturizing and smoothing wrinkles are realized.

The present invention in a preferred example may be further configured to: the paint comprises the following components in parts by weight: 3 parts of emulsifier, 8 parts of humectant, 5 parts of emollient, 0.2 part of thickener, 4 parts of birch bark extract, 3.5 parts of katsumadai seed extract, 1.5 parts of edelweiss extract, 1.5 parts of nicotinamide and 70 parts of deionized water; the stabilizer consists of 3 parts of polished round-grained rice extract and 1.5 parts of veronica pubescens extract.

The present invention in a preferred example may be further configured to: the preparation method of the polished round-grained rice extract comprises the following steps: grinding fresh polished round-grained rice, and freeze-drying for 12-24 hours under the conditions that the vacuum degree is 0.1-0.3 MPa and the temperature is-75-85 ℃ to obtain polished round-grained rice powder; then adding an ethanol solution with the volume concentration of 80-100% at the temperature of 80-95 ℃, and stirring for 20-40 min, wherein the material-to-liquid ratio of the polished round-grained rice powder to the ethanol solution is 1g (25-45) ml, so as to obtain a polished round-grained rice crude extract; and concentrating to obtain a concentrated solution, then cooling to 25-30 ℃, adding an ethanol solution with the volume concentration of 30-50% and 6-8 times of the volume of the concentrated solution, and centrifuging and filtering to obtain a filtrate to obtain the polished round-grained rice extract.

Further, the preparation method of the polished round-grained rice extract comprises the following steps: grinding fresh polished round-grained rice, and freeze-drying for 12-24 hours under the conditions that the vacuum degree is 0.1-0.3 MPa and the temperature is-75-85 ℃ to obtain polished round-grained rice powder; adding an ethanol solution with the volume concentration of 95% at the temperature of 93 ℃, and stirring for 20-40 min, wherein the material-to-liquid ratio of the polished round-grained rice powder to the ethanol solution is 1g (25-45) ml, so as to obtain a polished round-grained rice crude extract; and (3) concentrating to obtain a concentrated solution, then cooling to 28 ℃, adding a 45% ethanol solution with 6-8 times of the volume of the concentrated solution, centrifuging and filtering to obtain a filtrate, and thus obtaining the polished round-grained rice extract.

The preparation method is characterized in that: high temperature, the normal temperature after the high concentration ethanol solution is extracted, and the low concentration ethanol solution is extracted, the polished round-grained rice extract and the vernal flower extract obtained by adopting the special steps are cooperated to obviously improve the low temperature stability and the high temperature stability of the mask, which can be seen from table 4 in the test example of the invention, the appearance of the freckle removing mask prepared without adding the polished round-grained rice extract and the vernal flower extract is discolored and is obviously thinned, and the water phase and the oil phase are layered, which indicates that the stability is poor; and if only the japonica rice extract or the vernonia pubescens extract is added, the stability of the mask is also reduced.

The present invention in a preferred example may be further configured to: the preparation method of the vernalia pubescens extract comprises the following steps:

grinding whole fresh cymbidium floribundum to obtain cymbidium floribundum powder, extracting the cymbidium floribundum powder in purified water with the pH of 7.9-8.2 and the temperature of 50-60 ℃ for 60-120 min, and filtering to remove residues to obtain a cymbidium floribundum crude extract; filtering the flos Jasmini sambac crude extract with microfiltration membrane and ultrafiltration membrane to obtain flos Jasmini sambac extract; wherein the feed-liquid ratio of the vernalia pubescens powder to the purified water is 1g (10-24) ml.

By adopting the technical scheme, the active ingredients of the vernal inula flower can be effectively reserved by adopting a fresh extraction and proper pH value mode, and then the microfiltration membrane and the ultrafiltration membrane are adopted for filtering, so that the macromolecular ingredients are effectively removed, and the micromolecular flavone and phenol active matters are reserved, and further, the effect of fading color spots and whitening skin of the vernal inula flower extract is better.

The present invention in a preferred example may be further configured to: the emulsifier is at least one of cetearyl glucoside, laureth-7, C13-14 isoparaffin, and sorbitan stearate.

The present invention in a preferred example may be further configured to: the humectant is at least one of propylene glycol, butanediol, glycerol and 1, 2-hexanediol.

The present invention in a preferred example may be further configured to: the emollient is at least one of hydrogenated polyisobutene, isononyl isononanoate, polydimethylsiloxane and shea butter.

The present invention in a preferred example may be further configured to: the thickening agent is carbomer and/or sodium alginate.

By adopting the technical scheme, carbomer and sodium alginate are added into the freckle-removing mask liquid, the rheological property and the viscosity of the freckle-removing mask liquid are adjusted, the product is convenient to store for a long time, and the freckle-removing mask liquid has certain bacteriostatic ability, can replace the traditional preservative, has no stimulation to a human body, has no side effect, and can not cause allergy.

The invention also aims to provide a preparation method of the freckle-removing mask, which comprises the following steps:

s1, adding the emulsifier and the emollient into the oil phase pot, heating to 80-85 ℃, and uniformly stirring; adding the humectant and the thickener into deionized water, dispersing uniformly, heating to 80-85 ℃, and stirring uniformly until the humectant and the thickener are dissolved completely; pumping the water phase material into an emulsifying pot, slowly adding the oil phase material, and homogenizing;

s2, stirring the homogenized material for 5-10 min at the temperature of-10 to-15 ℃, wherein the stirring speed is 160-200 rpm/min; heating to 40-45 ℃, continuing stirring for 5-10 min at the stirring speed of 50-80 rpm/min, and then preserving heat for 20-30 min;

s3, continuously adding the birch bark extract, the alpinia katsumadai seed extract, the edelweiss extract and the nicotinamide, and uniformly stirring; and continuously adding the polished round-grained rice extract and the vernonia chinensis extract, uniformly stirring, and sampling and inspecting at 35-40 ℃ to obtain the freckle-removing facial mask.

By adopting the technical scheme, the plant extract is generally considered to be a natural substance in the cosmetic industry, and has a lot of benefits and effects when being added into cosmetics, but the inventor finds that bubbles are easily generated in a production test or a storage process in the earlier stage, and finds that effective and rapid bubble degradation can be realized by carrying out two times of treatment at different temperatures and different stirring speeds, and the stability of the freckle-removing mask liquid is further improved.

In summary, the invention includes at least one of the following beneficial technical effects:

1) the freckle-removing facial mask liquid provided by the invention is scientific and reasonable in overall formula collocation, can effectively remove color spots and brighten skin from multiple ways by compounding the Asian white birch bark extract, the Alpinia katsumadai seed extract, the edelweiss extract and the nicotinamide as effective components, is high in whitening component permeability, effectively penetrates into the skin bottom, is obvious in whitening and antioxidant effects, and meanwhile, contains multiple plant components which play a role in moisturizing and replenishing water, and is particularly suitable for quickly brightening the skin after being decocted;

2) the freckle-removing mask liquid creatively adopts the polished round-grained rice extract and the vernal flower extract which are prepared by a special process to be cooperated as a stabilizer, so that the tolerance of the freckle-removing mask to temperature is obviously improved, the freckle-removing mask liquid is not easily influenced by the temperature, and the low-temperature stability and the high-temperature stability are good.

Detailed Description

The present invention is further illustrated by the following specific examples, which are not intended to limit the invention in any way. Reagents, methods and apparatus used in the present invention are conventional in the art unless otherwise indicated.

Unless otherwise indicated, reagents and materials used in the following examples are commercially available.

In the following examples and comparative examples: the information on the purchasers of some of the raw materials is shown in Table 1.

TABLE 1

Raw materials	Manufacturer of the product
		Semen Alpiniae extract	Xian jin Green bioengineering technologies GmbH
Betula alba bark extract	Shanxi Yikang dragon biotechnology limited company
		Extract of edelweiss	Gansu Probiotics Biotech Ltd

Example 1 preparation method of polished round-grained rice extract

Grinding fresh japonica rice, sieving with a 200-mesh sieve, freeze-drying at-75 deg.C under a vacuum degree of 0.1MPa for 12h to obtain japonica rice powder, adding 80% ethanol solution at 80 deg.C, stirring for 20min, and collecting crude extract of japonica rice at a material-to-liquid ratio of 1g to 25 ml; evaporating and concentrating the crude extract of the japonica rice to 60% of the original volume to obtain a concentrated solution, then cooling to 25 ℃, adding an ethanol solution with the volume concentration of 30% and 6 times of the volume of the concentrated solution, centrifugally filtering, taking a filtrate, and removing ethanol to obtain the extract of the japonica rice.

Example 2 preparation of polished round-grained rice extract

Grinding fresh japonica rice, sieving with a 100-mesh sieve, freeze-drying at-85 deg.C under a vacuum degree of 0.3MPa for 24h to obtain japonica rice powder, adding 100% ethanol solution at 95 deg.C, stirring for 40min, and obtaining crude extract of japonica rice, wherein the material-to-liquid ratio of the japonica rice powder to the ethanol solution is 1g:45 ml; evaporating and concentrating the crude extract of the japonica rice to 50% of the original volume to obtain a concentrated solution, then cooling to 30 ℃, adding an ethanol solution with the volume concentration of 50% and 8 times of the volume of the concentrated solution, centrifugally filtering, taking a filtrate, and removing ethanol to obtain the extract of the japonica rice.

Example 3 preparation method of polished round-grained rice extract

Grinding fresh semen oryzae Sativae, sieving with 100 mesh sieve, and freeze drying at-80 deg.C under vacuum degree of 0.25MPa for 24 hr to obtain semen oryzae Sativae powder; adding 95% ethanol solution at 93 deg.C, stirring for 35min, wherein the material-to-liquid ratio of semen oryzae Sativae powder to ethanol solution is 1g:30ml, to obtain semen oryzae Sativae coarse extractive solution; evaporating and concentrating the crude extract of the japonica rice to 40% of the original volume to obtain a concentrated solution, then cooling to 28 ℃, adding a 45% ethanol solution with 6 times of the volume of the concentrated solution, centrifuging and filtering, taking the filtrate, and removing ethanol to obtain the extract of the japonica rice.

Example 4 preparation of extract of Jasminum lanceolatum

Feeding fresh whole plant of the vernalia pubescens into a low-temperature extraction tank, crushing for 20min to obtain vernalia pubescens powder, extracting for 90min in purified water with the pH of 8.1 and the temperature of 55 ℃, wherein the material-liquid ratio of the vernalia pubescens powder to the purified water is 1g:17ml, and filtering to remove residues to obtain a coarse extract of the vernalia pubescens; the extract of the veronicastrum pubescens is obtained by passing the crude extract of the veronicastrum pubescens through a 0.2um membrane and then passing through a 4000Da membrane.

Examples 5 to 9, the spot-removing mask and the preparation method thereof

TABLE 2 examples 5~ 9 speckle removing facial mask formula and its dosage (KG)

Note: the japonica rice extract in examples 5 to 7 corresponds to the japonica rice extract prepared in examples 1 to 3; the japonica rice extracts described in examples 8 and 9 correspond to the japonica rice extract prepared in example 3.

Example 5 a method of preparing a spot removing mask, comprising the steps of:

s1, putting cetearyl glucoside, laureth-7, C13-14 isoparaffin, isononyl isononanoate, polydimethylsiloxane and shea butter into an oil phase pot, heating to 80 ℃, and uniformly stirring; adding glycerol, 1, 2-hexanediol, carbomer and sodium alginate into deionized water, dispersing uniformly, adding into a reaction kettle, heating to 80 deg.C, and stirring uniformly to dissolve completely; pumping the water phase material into an emulsifying pot, slowly adding the oil phase material, and homogenizing;

s2, stirring the homogenized material for 5min at the temperature of-10 ℃, wherein the stirring speed is 160 rpm/min; heating to 40 ℃, continuing stirring for 5min at the stirring speed of 50rpm/min, and then preserving heat for 20 min;

s3, continuously adding the birch bark extract, the alpinia katsumadai seed extract, the edelweiss extract, the nicotinamide and the triethanolamine, and uniformly stirring at the stirring speed of 200rpm/min for 30 min; and continuing adding the polished round-grained rice extract and the veronica pubescens extract, stirring uniformly, sampling at 38 ℃ and inspecting to obtain the freckle-removing mask liquid.

The preparation method of the freckle-removing facial mask in the embodiments 6-7 is similar to that in the embodiment 5, and is different in that the homogenized material is continuously stirred for 10min at the temperature of-15 ℃ in the step S2, and the stirring speed is 200 rpm/min; heating to 45 deg.C, stirring at 80rpm/min for 10min, and keeping the temperature for 30 min.

The preparation method of the freckle-removing facial mask in the embodiments 8-9 is similar to that in the embodiment 5, and is different in that the homogenized material is continuously stirred at the temperature of-12 ℃ for 8min in the step S2, wherein the stirring speed is 180 rpm/min; heating to 40 deg.C, stirring at 70rpm/min for 10min, and keeping the temperature for 25 min.

Comparative example 1

The difference from the example 9 is that the formulation does not contain the japonica rice extract and the vernalia pubescens extract, the formula is supplemented with the same amount of deionized water, and other formulations and parameters are the same as the example 9.

Comparative example 2

The difference from example 9 is that the formulation does not contain the japonica rice extract, and the formulation is supplemented with the same amount of deionized water, and other formulations and parameters are the same as those of example 9.

Comparative example 3

The difference from example 9 is that the formula does not contain the chamomile extract, the formula is supplemented with the same amount of deionized water, and other formulas and parameters are the same as those in example 9.

Comparative example 4

The difference from the embodiment 9 is that the preparation of the polished round-grained rice extract omits the high-temperature and high-concentration ethanol solution extraction steps, and the specific steps are as follows:

grinding fresh semen oryzae Sativae, sieving with 100 mesh sieve, and freeze drying at-80 deg.C under vacuum degree of 0.25MPa for 24 hr to obtain semen oryzae Sativae powder; adding 6 times volume of 45% ethanol solution of semen oryzae Sativae powder at 28 deg.C, centrifuging, filtering, and removing ethanol to obtain semen oryzae Sativae extract.

Comparative example 5

The difference from the embodiment 9 is that the preparation of the polished round-grained rice extract omits the normal-temperature and low-concentration ethanol solution extraction step, and the specific steps are as follows:

grinding fresh semen oryzae Sativae, sieving with 100 mesh sieve, and freeze drying at-80 deg.C under vacuum degree of 0.25MPa for 24 hr to obtain semen oryzae Sativae powder; adding 95% ethanol solution at 93 deg.C, stirring for 35min, wherein the material-to-liquid ratio of semen oryzae Sativae powder to ethanol solution is 1g:30ml, to obtain semen oryzae Sativae coarse extractive solution; evaporating and concentrating the crude extract of polished round-grained rice to 40% of the original volume to obtain a concentrated solution, namely the polished round-grained rice extract.

Test example I, high temperature, Low temperature storage stability test

The freckle-removing facial masks prepared in examples 5-9 and comparative examples 1-5 are stored at-5 ℃ for 24 hours, then stored at room temperature for 24 hours, then stored in a thermostat at 40 ℃ for 24 hours, and are sequentially circulated for 3 times, the stability of the facial masks is observed, whether the facial masks have the phenomena of discoloration, thinning, layering and the like is observed, the high-low temperature stability of the facial masks is judged according to the test results, and the results are shown in table 4.

TABLE 4 stability test results

Group of	Appearance of the product
		Example 5	No color change, no thinning and layering
Example 6	No color change, no thinning and layering
		Example 7	No color change, no thinning and layering
Example 8	No color change, no thinning and layering
		Example 9	No color change, no thinning and layering
Comparative example 1	Has the phenomena of color change, obvious thinning and layering
		Comparative example 2	Has the phenomena of color change, obvious thinning and no layering
Comparative example 3	Has obvious color change, thinning phenomenon and no obvious layering
		Comparative example 4	Has obvious color change, no thinning and layering
Comparative example 5	Has the phenomena of color change, thinning and no layering

As can be seen from table 4, the freckle removing mask prepared in examples 5 to 9 has no change in color and no thinning or delamination after high and low temperature cycling tests, which indicates that the low temperature stability and the high temperature stability are good, and example 9 is the best example.

The freckle removing mask prepared in the comparative example 1 is not added with the polished round-grained rice extract and the vernal flower extract, has color change, and has obvious thinning and layering phenomena under the same test conditions, so that the addition of the polished round-grained rice extract and the vernal flower extract has great influence on the low-temperature stability and the high-temperature stability of the freckle removing mask, and the addition of the polished round-grained rice extract and the vernal flower extract can obviously improve the temperature tolerance of the freckle removing mask, so that the freckle removing mask is not easily influenced by temperature.

The freckle removing facial mask prepared in the comparative example 2 has the phenomena of color change and obvious thinning and has no layering phenomenon under the same test conditions, and the freckle removing facial mask prepared in the comparative example 3 has the phenomena of color change, obvious thinning and unobvious layering under the same test conditions, which indicates that if only one of the two is used as a stabilizer, the same technical effect cannot be obtained. The inventors have studied the mechanism of the above effect, and speculated that it is more likely that the vernalia pubescens extract and the japonica rice extract interact with each other to form the effect of the stable component.

The freckle-removing facial mask prepared in the comparative example 4 has obvious discoloration phenomenon and no thinning and layering phenomena under the same test conditions; the freckle-removing facial mask prepared in the comparative example 5 has the phenomena of color change and thinning and no layering under the same test conditions, and shows that the low-temperature stability and the high-temperature stability of the freckle-removing facial mask can be remarkably improved by the cooperation of the polished round-grained rice extract and the vernal flower extract obtained through the special steps.

Test example two, in vitro transdermal test

Taking a healthy SPF male mouse with Kunming breed, weighing (20 +/-2) g, removing the neck of the mouse, killing the mouse, taking the abdominal skin of the mouse, removing the fat layer, scraping the mouse hair on the skin of the mouse, washing the mouse with normal saline, fixing the skin of the mouse between a diffusion pool and a receiving pool, wherein the cuticle layer of the skin faces the diffusion pool, the dermis layer faces the receiving pool and is just contacted with a solvent in the receiving pool to prevent bubbles from being generated. The volume of the receiving cell was 15 mL. Placing 1mL of the freckle-removing facial mask liquid prepared in the embodiments 5-9 and the comparative examples 1-3 of the invention into a diffusion cell, adding distilled water into a receiving cell in which a magnetic stirrer is added in advance, placing the receiving cell on a magnetic stirrer of an intelligent transdermal tester, setting the water bath temperature at 37 ℃, stirring at the speed of 350r/min, sampling through a sampling port after 2 hours (simultaneously supplementing equivalent receiving liquid), filtering through a 0.22 mu m microporous filter membrane, performing chromatographic analysis, and calculating the nicotinamide permeability.

Niacinamide permeability ═ (amount of niacinamide in the receiving tank/amount of niacinamide added) × 100%

TABLE 5

Group of	Nicotinamide Permeability%
		Example 5	32.1％
Example 6	30.5％
		Example 7	36.3％
Example 8	34.7％
		Example 9	42.6％
Comparative example 1	20.4％
		Comparative example 2	30.1％
Comparative example 3	29.8％

As can be seen from the data in table 5, the permeability of niacinamide in the spot removing facial masks prepared in examples 5 to 9 can be as high as 42.6%, and thus, the whitening active ingredients in the spot removing facial mask prepared in the present invention have good permeability, and if the mask application time is prolonged, the permeability of the whitening active ingredients can be increased, and the whitening effect can be better exerted.

Compared with example 9, the freckle removing facial mask liquid prepared in comparative examples 1-3 is not added with the japonica rice extract and the vernal flower extract, or is only added with one of the japonica rice extract and the vernal flower extract, and the permeation amount of nicotinamide is slightly lower, which shows that the japonica rice extract and the vernal flower extract have certain influence on the permeability of nicotinamide.

Test example III Spot removing, whitening and moisturizing test

The purpose of the test is as follows: in order to verify the spot lightening effect of the spot-removing mask of the present invention, examples 5 to 9 and comparative examples 1 to 3 were tested.

The test method comprises the following steps: 80 volunteers with age pigment, chloasma and pigmentation after sun exposure were selected and randomly divided into 8 groups, each group of subjects was externally applied with the masks of examples 5-9 and comparative examples 1-3, and used once every night after face cleaning for 28 days continuously, before and after use, the color reader spectrophotometer (C R-10, Konica Minolta, Japan) was used to test the L, b value of the volunteers; Δ L ═ L_t-L₀Wherein L is_tTo use the skin L value after t period, L₀Is the skin L value before use; Δ b ═ b_t-b₀Wherein b is_tTo use the b value of the skin after the t period, b₀Is the pre-application skin b value; the larger the Δ L value, the better the Δ b value.

The moisture content of the skin of the subject before use and the moisture content of the skin of the subject after 28 days of use are tested by a skin moisture detector Corneometer CM825, and the test is repeated for 5 times respectively, and the average value is calculated, so that the skin moisture content increase rate is calculated.

In the formula, MMV₀MMV for pre-use skin; MMV_tIs the skin MMV t period after use.

TABLE 6 test results

As can be seen from the data in table 6, the whitening components in the spot-removing mask solutions prepared in examples 5 to 9 have better effects of penetrating the skin and lightening spots, wherein the spot-lightening effect of example 9 is the best, and more melanin is reduced, so that the skin has substantial effects of whitening and removing spots, and the spot-removing mask solutions prepared in examples 5 to 9 have better moisturizing and anti-aging effects.

From comparative examples 1 to 3, it can be seen that the effect of lightening spots is reduced when the veronica pubescens extract and the japonica rice extract are absent or one of the veronica pubescens extract and the japonica rice extract is absent, which indicates that the veronica pubescens extract has the effect of lightening spots such as chloasma and freckles when added into the mask, can effectively whiten the skin, improve the dull skin caused by melanin pigmentation, deeply penetrate into the bottom layer of the skin to supplement water and lock water, prevent the spots from rebounding, and make the skin white, tender and smooth.

The above embodiments are preferred embodiments of the present invention, but the present invention is not limited to the above embodiments, and any other changes, modifications, substitutions, combinations, and simplifications which do not depart from the spirit and principle of the present invention should be construed as equivalents thereof, and all such changes, modifications, substitutions, combinations, and simplifications are intended to be included in the scope of the present invention.

Claims

1. The freckle-removing mask is characterized by comprising the following components in parts by weight: 2-6 parts of an emulsifier, 6-10 parts of a humectant, 5-8 parts of an emollient, 0.1-0.2 part of a thickener, 1-6 parts of a birch bark extract, 1-5 parts of a katsumadai seed extract, 1-3 parts of a edelweiss extract, 1-2 parts of nicotinamide, 65-75 parts of deionized water, 3-5 parts of a polished round-grained rice extract and 1.5-3 parts of a vernal flower extract;

the preparation method of the polished round-grained rice extract comprises the following steps: grinding fresh polished round-grained rice, and freeze-drying for 12-24 hours under the conditions that the vacuum degree is 0.1-0.3 MPa and the temperature is-75-85 ℃ to obtain polished round-grained rice powder; adding an ethanol solution with the volume concentration of 80-100% at the temperature of 80-95 ℃, and stirring for 20-40 min, wherein the material-liquid ratio of the polished round-grained rice powder to the ethanol solution is 1g: (25-45) ml to obtain a coarse extract of the polished round-grained rice; concentrating to obtain a concentrated solution, cooling to 25-30 ℃, adding an ethanol solution with the volume concentration of 30-50% and 6-8 times of the volume of the concentrated solution, centrifuging and filtering, and taking a filtrate to obtain a polished round-grained rice extract;

the preparation method of the vernalia pubescens extract comprises the following steps:

2. The spot removing mask according to claim 1, wherein the preparation method of the japonica rice extract comprises: grinding fresh polished round-grained rice, and freeze-drying for 12-24 hours under the conditions that the vacuum degree is 0.1-0.3 MPa and the temperature is-75-85 ℃ to obtain polished round-grained rice powder; adding an ethanol solution with the volume concentration of 95% at the temperature of 93 ℃, and stirring for 20-40 min, wherein the material-to-liquid ratio of the polished round-grained rice powder to the ethanol solution is 1g (25-45) ml, so as to obtain a polished round-grained rice crude extract; and (3) concentrating to obtain a concentrated solution, then cooling to 28 ℃, adding a 45% ethanol solution with 6-8 times of the volume of the concentrated solution, centrifuging and filtering to obtain a filtrate, and thus obtaining the polished round-grained rice extract.

3. The spot removing mask according to claim 1, wherein the emulsifier is at least one of cetearyl glucoside, laureth-7, C13-14 isoparaffin, and sorbitan stearate.

4. The spot removing mask according to claim 1, wherein the moisturizer is at least one of propylene glycol, butylene glycol, glycerin and 1, 2-hexanediol.

5. The spot-removing mask pack according to claim 1, wherein the emollient is at least one of hydrogenated polyisobutene, isononyl isononanoate, polydimethylsiloxane, and shea butter.

6. The spot removing mask according to claim 1, wherein the thickener is carbomer and/or sodium alginate.

7. A method for preparing a spot removing mask according to claim 1, comprising the steps of: