CN115487123A - Mild whitening composition containing plant polyphenol and application thereof - Google Patents

Mild whitening composition containing plant polyphenol and application thereof Download PDF

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CN115487123A
CN115487123A CN202111317713.7A CN202111317713A CN115487123A CN 115487123 A CN115487123 A CN 115487123A CN 202111317713 A CN202111317713 A CN 202111317713A CN 115487123 A CN115487123 A CN 115487123A
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percent
composition containing
extract
whitening composition
mild
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方武荣
张岷
樊一斌
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Shanghai Lishudan Pharmaceutical Technology Co ltd
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Shanghai Lishudan Pharmaceutical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/522Antioxidants; Radical scavengers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

The invention relates to the field of A61Q19/00, in particular to a mild whitening composition containing plant polyphenol and application thereof. The mild whitening composition containing plant polyphenol at least comprises the following raw materials: niacinamide, tranexamic acid and plant extract compositions. The whitening and skin-care essence of the mild whitening composition containing the plant polyphenol comprises the following raw materials in percentage by mass: 6 to 10 percent of mild whitening composition containing plant polyphenol, 0.5 to 1 percent of ester polymer, 0.5 to 2 percent of emulsifier, 0.05 to 0.2 percent of chelating agent, 5 to 10 percent of humectant, 1 to 10 percent of skin conditioner, 6 to 10 percent of emollient, 0.3 to 0.8 percent of antibacterial composition and the balance of deionized water. The composition and the skin care essence prepared by the application have good low-irritation effect and spot whitening effect, effectively enhance the storage stability of the composition, reduce the phenomenon of layered precipitation, and are suitable for popularization in the field of skin care products.

Description

Mild whitening composition containing plant polyphenol and application thereof
Technical Field
The invention relates to the field of A61Q19/00, in particular to a mild whitening composition containing plant polyphenol and application thereof.
Background
With the progress of society and the development of economy and the acceleration of urban life rhythm, the pressure born by people in the life process is gradually increased, and more people begin to have various skin problems under the influence of environment. Especially, female consumers have more remarkable influence on their skin due to stress and external environment, and it has been investigated that, in recent years, more than fifty percent of women consider remarkable problems of their own skin, especially facial skin, and among them, freckles, chloasma, age spots, dark yellow skin, blackened skin, and the like become the most important skin problems in recent years. Therefore, more and more whitening skin care type skin is popular with many female consumers, but some existing whitening compositions also have obvious disadvantages.
The prior art (CN 201610206760.7) provides a cosmetic composition for whitening, which is prepared mainly from chamomile extract, saussurea involucrate extract, glutamic acid, yeast extract, salicylic acid, glucosamine and other raw materials, and claims to have a whitening effect, and at the same time, the cosmetic composition has good safety, stability, appearance and skin irritation. However, in actual use, the composition has the effects of reforming the skin and whitening the skin by promoting the skin cuticle to fall off through the salicylic acid so as to remove melanin. However, the use of salicylic acid tends to cause irritation to the cell skin, so that the composition tends to cause great skin irritation while whitening, and further deteriorates the skin surface state.
Therefore, there is a need for a mild whitening composition that has excellent whitening effects, and also effectively reduces the irritation effect of the composition to the skin, and has good storage stability.
Disclosure of Invention
A mild whitening composition containing plant polyphenol at least comprises the following components: niacinamide, tranexamic acid and plant extract composition.
As a preferred embodiment, the plant extract composition is a mixed composition of at least two of raspberry fruit plant extract, mulberry root bark extract, centella asiatica extract, gentian extract, tetrandra root extract, turmeric root extract, and withania extract.
As a preferred embodiment, the plant extract composition comprises a raspberry fruit/mulberry root bark/centella asiatica mixed composition, and the components mainly comprise raspberry fruit extract, mulberry root bark extract, centella asiatica extract and p-hydroxyacetophenone.
As a preferred embodiment, the raspberry fruit/mulberry root bark/centella asiatica mixture composition is purchased from gaoney biotechnology limited, guangzhou; the mass percentages of the raspberry fruit extract, the mulberry root bark extract, the centella extract and the p-hydroxyacetophenone are 47%:47%:3%:3 percent.
As a preferred embodiment, the botanical extract composition comprises a gentian/tetrandra root mixture composition, which mainly comprises gentian extract, tetrandra root extract, propylene glycol and water.
As a preferred embodiment, the gentian/tetrandra root mixture composition is purchased from gaoney biotechnology limited, guangzhou; the mass percentages of the water, the propylene glycol, the gentian extract and the tetrandra root extract are 57.5%:37.5%:2.5%:2.5 percent.
As a preferable scheme, the mass ratio of the raspberry fruit/mulberry root bark/centella asiatica mixed composition to the gentian/tetrandra root mixed composition is 2-3:4.
In the application, the whitening effect of the composition is effectively improved and the composition has a more stable storage-resistant effect by compounding and adding the raspberry fruit/mulberry root bark/centella asiatica mixed composition and the gentian/tetrandra root mixed composition. The applicant speculates that: the two mixtures added in the application can synergistically promote the free effect of polyphenol active substances in the composition under the synergistic action of the mass ratio of 2-3:4, and the polyphenol substances form stable polybasic chelate under the coordination of metal ions of the composition, so that the storage stability effect of the polyphenol active substances in the composition is improved, and the phenolic hydroxyl structure of the polyphenol active substances can be evolved into quinone structure when in use, thereby consuming environmental oxygen and further promoting the capture capacity of the polyphenol active substances on free radicals.
In a second aspect of the present invention, a whitening and skin-caring essence containing the mild whitening composition containing plant polyphenols is provided.
As a preferred scheme, the raw materials at least comprise the following mass percent: 6 to 10 percent of mild whitening composition containing plant polyphenol, 0.5 to 1 percent of ester polymer, 0.5 to 2 percent of emulsifier, 0.05 to 0.2 percent of chelating agent, 5 to 10 percent of humectant, 1 to 10 percent of skin conditioner, 6 to 10 percent of emollient, 0.3 to 0.8 percent of antibacterial composition and the balance of deionized water.
As a preferable scheme, the ester polymer is at least one of acrylate/C10-30 alkanol acrylate cross-linked polymer and acrylate/sodium acryloyldimethyl taurate polymer.
As a preferable mode, the ester polymer is acrylate/C10-30 alkanol acrylate cross-linked polymer and hydroxyethyl acrylate/sodium acryloyldimethyl taurate polymer.
As a preferable scheme, the ester polymer is an acrylate/C10-30 alkanol acrylate cross-linked polymer and a hydroxyethyl acrylate/sodium acryloyldimethyl taurate polymer, wherein the mass ratio of the acrylate/C10-30 alkanol acrylate cross-linked polymer to the hydroxyethyl acrylate/sodium acryloyldimethyl taurate polymer is 6-7: 45 to 55.
In a preferred embodiment, the emulsifier is at least one of cetearyl olive oleate, sorbitan olive oleate, lecithin, and polyethylene glycol.
In a preferred embodiment, the emulsifier is at least one of cetearyl olive oleate, sorbitan olive oleate, lecithin, and polyethylene glycol.
As a preferred embodiment, the emulsifier is a mixture of cetearyl olive oleate and sorbitan olive oleate.
As a preferred embodiment, the emulsifier is purchased from shanghai Rong Hai biotechnology limited; the mass ratio of the cetearyl alcohol olive oleate to the sorbitan olive oleate is 6:4.
As a preferred embodiment, the chelating agent is at least one of disodium EDTA and EFTA tetrasodium.
As a preferred embodiment, the chelating agent is disodium EDTA.
In a preferable embodiment, the humectant is at least one of hydrolyzed corn starch, glyceryl polyether-26, butylene glycol, glycerin, sorbitol and hyaluronic acid.
As a preferred embodiment, the skin conditioning agent is sodium hyaluronate, arginine and bisabolol; the humectant necessarily comprises hydrolyzed corn starch.
As a preferable scheme, the mass ratio of the nicotinamide, the tranexamic acid and the hydrolyzed corn starch is 2-5: 3 to 4:1 to 1.5.
In the application, the whitening effect, the absorption effect and the stability of the composition are effectively improved by compounding the nicotinamide, the tranexamic acid and the hydrolyzed corn starch. The applicant speculates that: when the mass ratio of the nicotinamide, the tranexamic acid and the hydrolyzed corn starch is 2-5: 3 to 4: 1-1.5, the addition of nicotinamide can effectively improve the content level of ceramide and free fatty acid in the skin, effectively promote the carrier effect of free substances on tranexamic acid, and improve the stability of the tranexamic acid on the skin surface; further, the existence of the hydrolyzed corn starch can be used as a attaching carrier of the tranexamic acid in a composition system, thereby effectively loading and dissolving residual tranexamic acid components and reducing the precipitation and delamination of the tranexamic acid components during long-term storage.
As a preferable scheme, the essence is also added with a glycol composition.
As a preferred embodiment, the components of the glycol composition include 1,2-pentanediol, 1,2-hexanediol, glycerol, water, and beta-glucan.
As a preferred approach, the glycol composition is purchased from baihabo chemical co, shanghai; the weight percentage of 1,2-pentanediol, 1,2-hexanediol, glycerol, beta-glucan and water is 2%:1%:20%:0.4%:76.6 percent.
As a preferable mode, the mass ratio of the glycol composition to tranexamic acid is 2 to 3:3 to 4.
According to the application, the glycol composition and the tranexamic acid are added, the proportion of the glycol composition and the tranexamic acid is limited, the effects of moisturizing, whitening and the like of the composition are effectively improved, and the overall stability of the composition is further promoted. The applicant speculates that: the anhydrous polyalcohol system in the system can effectively avoid the electron losing reaction of tranexamic acid in the composition and effectively reserve the active ingredient of the tranexamic acid in the composition. At the same time, however, the solubility of tranexamic acid in alcohol systems is low, and when the mass ratio of the glycol composition to tranexamic acid is 2-3: 3-4, the solubility of the ascorbic acid in a polyol complex system can be obviously improved, and the ascorbic acid can be effectively combined with other components in the composition, so that a synergistic effect of enhancing the performance of the composition is achieved, and the high solubility of the tranexamic acid can effectively ensure that the tranexamic acid can play a good skin care effect and promote the activity of polyphenol substances in the plant extract.
As a preferred embodiment, the emollient is squalane, dimethicone and cetearyl hexanoate; the mass ratio of squalane, polydimethylsiloxane to cetearyl ethyl hexanoate is 2-3: 3 to 5:3 to 5.
Has the advantages that:
1. the whitening composition essence provided by the invention can effectively perform a synergistic whitening effect on multiple skins through active ingredients such as plant polyphenol in a plant extraction mixture, effectively remove color spots, change the phenomena of dark yellow skin and the like, and is a whitening composition with an excellent market prospect.
2. The essence containing the whitening composition provided by the invention can effectively improve the stability of organic acid raw materials in a mixed composition system by adding a plurality of mixed diols, so that the storage stability of the composition in a high-temperature and low-temperature storage state is reduced.
3. The whitening composition essence provided by the application of the invention can be added by compounding various non-plant extracted active raw materials to further improve the skin surface stability and the permeation and absorption effects of the composition in use, and has excellent synergistic whitening and skin care effects.
Drawings
Fig. 1 is a skin irritation test report of a whitening skin care essence containing a mild whitening composition containing plant polyphenols obtained in example 1 of the present application.
Fig. 2 is a spot test report of the whitening skin care essence containing the mild whitening composition containing plant polyphenols obtained in example 1 of the present application.
Detailed Description
Example 1
Example 1 in a first aspect, a whitening and skin-care essence containing a mild whitening composition containing plant polyphenols is provided, and raw materials comprise the following components in percentage by mass: mild whitening compositions containing plant polyphenols (niacinamide 4%, tranexamic acid 3% and plant extract composition 1.75%), acrylates/C10-30 alkanol acrylate crosspolymer 0.07%, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer 0.5%, disodium EDTA 0.1%, emulsifier (mixture of cetearyl olivate and sorbitan olivate) 1%, hydrolyzed corn starch 1%, glyceryl polyether-26%, sodium hyaluronate 0.1%, arginine 0.07%, squalane 2%, polydimethylsiloxane 3%, cetearyl ethyl hexanoate 3%, butylene glycol 3%, glycol composition (1,2-pentanediol, 1,2-hexanediol, glycerol, water and β -glucan) 2%, bisabolol 0.2%, antibacterial composition (glyceryl caprylate, 1,2 hexanediol, caprylyl hydroxamic acid and ethylhexylglycerol, mass% 2.75%: 3425%: z11.5%: 3410%, balance of deionized water 0.6%.
In the present application, the plant extract composition: rubi fructus/cortex Mori/herba Centellae mixed composition (Rubi fructus extract, cortex Mori extract, herba Centellae extract and p-hydroxyacetophenone) 0.75%, and radix Gentianae/radix Stephaniae Japonicae mixed composition (radix Gentianae extract, radix Stephaniae Japonicae extract, propylene glycol and water) 1%
In a second aspect of this embodiment, a method for preparing a whitening and skin-care essence containing the mild whitening composition containing plant polyphenols is provided: firstly, configuring each component phase according to the following formula table; (2) Adding the component A into a preparation pot, fully wetting, stirring and heating to 85 ℃, sequentially adding the component B, and uniformly stirring; (3) Adding the component C into an oil phase pot, heating to 85 ℃, and uniformly stirring; (4) Pumping the materials in the oil phase pot into a preparation pot, homogenizing and emulsifying for 5min, and cooling; (5) cooling to 48 ℃, adding the component D, and uniformly stirring; (6) After uniformly stirring, measuring physicochemical indexes such as viscosity, pH value and the like, cooling to below 45 ℃ after passing inspection, and discharging to obtain the product.
A formula table:
Figure BDA0003344601370000081
in this example, the antimicrobial composition was purchased from Ai Zhuo, guangzhou, biotechnology limited.
In this example, the gentian/tetrandra root mixture composition was purchased from gaoney biotechnology limited, guangzhou; the mass percentages of the water, the propylene glycol, the gentian extract and the tetrandra root extract are 57.5%:37.5%:2.5%:2.5 percent.
In this example, a mixture of cetearyl olivate and sorbitan olivate was purchased from Rong Hai biotechnology, inc; the mass ratio of the cetearyl alcohol olive oleate to the sorbitan olive oleate is 6:4.
In this example, the raspberry fruit/mulberry root bark/centella asiatica hybrid composition was purchased from ganery biotechnology limited, guangzhou; the mass percentages of the raspberry fruit extract, the mulberry root bark extract, the centella extract and the p-hydroxyacetophenone are 47%:47%:3%:3 percent.
In this example, the glycol composition was purchased from baihaobo chemical co, shanghai; the weight percentage of 1,2-pentanediol, 1,2-hexanediol, glycerol, beta-glucan and water is 2%:1%:20%:0.4%:76.6 percent.
In this example, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer was purchased from Shanghai Baihabo chemical Co., ltd.
In this example, the polydimethylsiloxane was purchased from Shanghai collaborative industry development, inc.
In this example, hydrolyzed corn starch was purchased from Shanghai Rimu chemical science and technology, inc.
In this example, the acrylic/C10-30 alkanol acrylate crosspolymer was purchased from Shanghai Mega-Heng industries, inc.
Example 2
The embodiment of the present invention is different from embodiment 1 in that: the content of tranexamic acid was 4% and the content of the glycol composition was 3%.
Comparative example 1
The embodiment of this comparative example is the same as example 1 except that: the content of tranexamic acid is 3%, and the content of the glycol composition is 0.5%.
Comparative example 2
The embodiment of this comparative example is the same as example 1 except that: the content of nicotinamide is 1%, the content of tranexamic acid is 4%, and the content of hydrolyzed corn starch is 0.5%.
Comparative example 3
The embodiment of this comparative example is the same as example 1 except that: the content of the mixed composition of raspberry fruit/mulberry root bark/centella is 0.1%.
Evaluation of Performance
1. And (3) irritation test: the compositions prepared in all examples and comparative examples were subjected to multiple skin irritation tests on the test subjects in accordance with the technical Specification for cosmetic safety (2015 edition).
The experimental animal is a rabbit, the experimental animal is raised in a single cage, and the experimental animal adapts to at least 3 days in the environment of the experimental animal room before the experiment. The hair on both sides of the spine of the experimental animal is cut off about 24 hours before the experiment, the hair removing range is 3cmX cm respectively, and the smearing area is 2.5cmX2.5cm.
The experimental method comprises the following steps: applying 0.5mL of the composition to the unhaired skin on one side, and applying the unhaired skin on the other side as control for 1 time per day for 14 days. Shearing hair before applying the hair on the day from the next day, and removing residual test substances with warm water. After one hour observation, the results were scored according to chapter 4 skin irritation/corrosivity test table 1 of technical specifications for cosmetic safety (2015 edition), the control and test areas were treated the same way, and the average score per animal per day was calculated according to the formula.
Wherein the skin irritation test result of the whitening skin care essence containing the mild whitening composition containing plant polyphenols obtained in example 1 is shown in fig. 1.
2. Skin patch test: the composition prepared in example 1 was subjected to a human skin patch test, and the test subjects were 30 persons, 10 persons in men, 20 persons in women, aged 31-59 years, and the average aged 49.0 ± 9.0 years, which met the volunteer selection criteria of the test subjects.
The test method comprises the following steps: selecting qualified spot test equipment, placing about 0.020-0.025 mL of a tested object in the spot test equipment by a closed spot patch experimental method, externally applying a hypoallergenic adhesive tape to the back of the tested object, taking out the tested object after 24 hours, observing skin reactions respectively at 0.5, 24 and 48 hours after removal, recording results according to the skin reaction grading standard in the 2015 edition of complete technical Specification for cosmetics, recording the results into a table 2 by using a blank control group, and recording the results into a complete test result shown in figure 2.
3. And (3) testing the stability: the compositions obtained in each of the examples and comparative examples were allowed to stand in an incubator at-10 ℃ and 45 ℃ for 14 days, respectively, and the room temperature state was observed after 14 days, and the results are shown in Table 1.
TABLE 1
Figure BDA0003344601370000111
TABLE 2
Figure BDA0003344601370000112
The embodiments 1 to 2, the comparative examples 1 to 3 and the table 1 show that the mild whitening composition containing plant polyphenol and the application thereof have good low-irritation effect and spot whitening effect, effectively enhance the storage stability of the composition, reduce the phenomenon of layering and precipitation, are suitable for popularization in the field of skin care products, and have wide development prospects. Wherein, the example 1 obtains the best performance index under the factors of the best preparation raw material proportion, the best preparation process and the like.

Claims (10)

1. The mild whitening composition containing plant polyphenol is characterized in that raw materials at least comprise the following components: niacinamide, tranexamic acid and plant extract composition.
2. The mild whitening composition containing plant polyphenols according to claim 1, characterized in that: the plant extract composition is a mixed composition of at least two of raspberry fruit plant extract, mulberry root bark extract, centella asiatica extract, gentian extract, tetrandra root extract, turmeric root extract and withania extract.
3. Use of the mild whitening composition containing plant polyphenols according to any one of claims 1-2, characterized in that: the whitening and skin-care essence containing the mild whitening composition containing the plant polyphenol.
4. The use of the mild whitening composition containing plant polyphenols according to claim 3, characterized in that: the whitening skin care essence at least comprises the following raw materials in percentage by mass: 6 to 10 percent of mild whitening composition containing plant polyphenol, 0.5 to 1 percent of ester polymer, 0.5 to 2 percent of emulsifier, 0.05 to 0.2 percent of chelating agent, 5 to 10 percent of humectant, 1 to 10 percent of skin conditioner, 6 to 10 percent of emollient, 0.3 to 0.8 percent of antibacterial composition and the balance of deionized water.
5. The use of the mild whitening composition containing plant polyphenols according to claim 4, characterized in that: the ester polymer is at least one of acrylate/C10-30 alkanol acrylate cross-linked polymer and acrylate/sodium acryloyldimethyl taurate polymer.
6. The use of the mild whitening composition containing plant polyphenols according to any one of claims 4 to 5, characterized in that: the emulsifier is at least one of cetearyl olive oleate, sorbitan olive oleate, lecithin and polyethylene glycol.
7. The use of the mild whitening composition containing plant polyphenols according to any one of claims 4 to 6, characterized in that: at least one of the chelating agents disodium EDTA and EFTA tetrasodium.
8. The use of the mild whitening composition containing plant polyphenols according to claims 4-7, characterized in that: the humectant is at least one of hydrolyzed corn starch, glyceryl polyether-26, butanediol, glycerol, sorbitol and hyaluronic acid.
9. The use of the mild whitening composition containing plant polyphenols according to claims 4-8, characterized in that: the skin conditioner is sodium hyaluronate, arginine and bisabolol; the humectant necessarily comprises hydrolyzed corn starch.
10. The use of the mild whitening composition containing plant polyphenols according to claim 9, characterized in that: the mass ratio of the nicotinamide, the tranexamic acid and the hydrolyzed corn starch is 2-5: 3 to 4:1 to 1.5.
CN202111317713.7A 2021-11-09 2021-11-09 Mild whitening composition containing plant polyphenol and application thereof Pending CN115487123A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117137845A (en) * 2023-10-12 2023-12-01 广州西子化妆品科技有限公司 Whitening and freckle-removing composition and preparation method and application thereof

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