CN112315843A

CN112315843A - Whitening and freckle removing essence and preparation method thereof

Info

Publication number: CN112315843A
Application number: CN202011404930.5A
Authority: CN
Inventors: 何陵玲; 张毅; 龚秋君; 刘淑晴
Original assignee: Guangdong Gadetin Daily Necessities Co ltd
Current assignee: Guangdong Gadetin Daily Necessities Co ltd
Priority date: 2020-12-03
Filing date: 2020-12-03
Publication date: 2021-02-05

Abstract

The invention relates to the field of cosmetics, and particularly relates to a whitening and freckle-removing essence and a preparation method thereof. The whitening and freckle-removing essence comprises a composition for improving skin color, a water phase component and an oil phase component; the composition for improving skin color comprises a whitening and freckle removing agent, a plant extract and a humectant. The whitening and freckle-removing essence has the advantages of being obvious in whitening effect, high in formula mildness, stable in product, stable in system, long-acting, moisturizing and the like, and the whitening and freckle-removing essence can effectively achieve the whitening and freckle-removing effects.

Description

Whitening and freckle removing essence and preparation method thereof

Technical Field

The invention relates to the field of cosmetics, and particularly relates to a whitening and freckle-removing essence and a preparation method thereof.

Background

Whitening is always sought by asian women, and with the improvement of the living standard and aesthetic standard of people, smooth, fair, and even skin with little speckles or pigment deposition is more and more advocated. The skin color becomes dark due to a plurality of factors such as natural aging and the like, and people can achieve the effect by applying whitening products such as whitening milk, whitening cream, whitening essence and the like. Wherein the whitening agent generally comprises ascorbic acid and its derivatives, arbutin, glabridin, etc. The whitening effect is achieved mainly by inhibiting the enzymatic activity related to the synthesis of eumelanin such as tyrosinase, inhibiting the transfer of melanin from the basal layer to the epidermal layer, and promoting the production of melatonin to inhibit the production of eumelanin.

The skin care products sold on the market are various, but the existing whitening products are added with too many synthetic chemical reagents and are easy to damage the skin. Particularly, a great amount of mercury and hydroquinone-containing preparations are added into part of whitening and freckle-removing cosmetics, which can rapidly achieve the effects of whitening and removing freckles, but the accumulation of toxic substances can cause facial skin necrosis of consumers, and incurable green spots or white spots are left. At present, hydroquinone has good whitening effect but has toxicity and carcinogenicity to a human body, so the hydroquinone is forbidden to be used in a resident product; arbutin has good whitening effect, but is easy to generate hydroquinone under certain conditions; ascorbic acid is unstable, easily oxidized in neutral or alkaline solutions, unstable under light and heat conditions, and easily yellowed after storage for a certain period of time, so many ascorbic acid derivatives such as ascorbic acid phosphate, ascorbic acid glucoside, and ascorbic acid ethyl ether appear.

Therefore, the invention needs to develop a whitening and freckle-removing essence capable of improving the stability and efficacy of a whitening agent in a cosmetic formula.

Disclosure of Invention

In order to solve the above problems, the present invention provides, in a first aspect, a whitening and spot-removing essence comprising a composition for improving skin color, a water phase component, an oil phase component; the composition for improving skin color comprises a whitening and freckle removing agent, a plant extract and a humectant.

As a preferred technical scheme, the whitening and freckle-removing agent comprises, by weight, 15-20 parts of tranexamic acid, 10-30 parts of nicotinamide, 0.5-1 part of a schizosaccharomyces cerevisiae fermentation product lysate, 5-10 parts of a rice fermentation product filtrate and 0.5-1 part of glabridin.

As a preferable technical scheme, the plant extract comprises one or more of magnolia sieboldii extract, mulberry root extract, undaria pinnatifida extract and hypsizygus marmoreus callus culture filtrate.

As a preferable technical scheme, the composition for improving skin color further comprises sodium metabisulfite, dipotassium glycyrrhizinate and distilled water.

As a preferable technical scheme, the composition for improving the skin color comprises, by weight, 31-62 parts of a whitening and freckle-removing agent, 2-5 parts of a plant extract, 8-12 parts of a humectant, 0.4-1.0 part of sodium metabisulfite, 0.5-0.8 part of dipotassium glycyrrhizinate and 25-60 parts of distilled water.

As a preferable technical scheme, the water phase component comprises, by weight, 0.2-0.6 part of thickening agent, 2-5 parts of glycerol, 1-3 parts of butanediol, 0.02-0.1 part of sodium hyaluronate and 75-90 parts of water.

As a preferred technical scheme, the thickening agent is selected from one or more of hydroxyethyl cellulose, xanthan gum and carbomer.

As a preferable technical scheme, the oil phase component comprises, by weight, 0.25-0.35 part of jojoba oil, 0.25-0.35 part of synthetic squalane, 0.8-1.2 parts of olive oil PEG-7 esters, 0.8-1.2 parts of hydrogenated castor oil and 0.08-0.12 part of tocopherol acetate.

As a preferable technical scheme, the whitening and freckle-removing essence further comprises polyhydric alcohol and a preservative.

The second aspect of the invention provides a preparation method of the whitening and freckle-removing essence, which comprises the following steps:

a. preparing an aqueous phase component;

b. preparing an oil phase component;

c. adding the oil phase component into the water phase component, homogenizing and emulsifying, stirring, cooling to 55-65 deg.C, adding pH regulator to adjust pH to 6-6.8 to obtain mixture 1;

d. dissolving antiseptic with polyalcohol, heating to 45-55 deg.C for dissolving completely, and adding into mixture 1 to obtain mixture 2;

e. preparation of a composition for improving skin color;

f. and adding the composition for improving the skin color into the mixture 2, and uniformly stirring to obtain the whitening and freckle-removing essence.

Has the advantages that: the composition for improving skin color provided by the invention adopts tranexamic acid and nicotinamide as whitening and freckle-removing components, inhibits the activity of tyrosinase, inhibits the oxidation reaction in the melanogenesis process, inhibits the expression and transfer of melanogenesis-related protein, and synergistically inhibits the formation of melanin and pigmented spots in multiple aspects. By scientific compounding of the whitening and freckle-removing agents, the whitening effect is more obvious, the formula is higher in mildness, the product is stable, and the whitening and freckle-removing essence can effectively achieve the effects of whitening and removing freckles and has the characteristics of stable system, long acting, moisture retention and the like.

Detailed Description

The technical features of the technical solutions provided by the present invention are further clearly and completely described below with reference to the specific embodiments, and the scope of protection is not limited thereto.

When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when the range "1 to 5" is disclosed, the described range should be construed as including the ranges "1 to 4", "1 to 3", "1 to 2", "2 to 3" and "3 to 4", "4 to 5" and "3 to 5", etc. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.

The singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. "optional" or "any" means that the subsequently described event or events may or may not occur, and that the description includes instances where the event occurs and instances where it does not.

In addition, the indefinite articles "a" and "an" preceding an element or component of the invention are not intended to limit the number requirement (i.e., the number of occurrences) of the element or component. Thus, "a" or "an" should be read to include one or at least one, and the singular form of an element or component also includes the plural unless the stated number clearly indicates that the singular form is intended.

In order to solve the technical problems, the invention provides a whitening and freckle-removing essence which comprises a composition for improving skin color, a water phase component and an oil phase component; the composition for improving skin color comprises a whitening and freckle removing agent, a plant extract and a humectant.

In one embodiment, the composition for improving skin color, the water phase component and the oil phase component are present in a mass ratio of 10: 84.25: 27.

composition for improving skin color

In one embodiment, the weight ratio of the whitening and freckle-removing agent to the plant extract to the humectant is (31-62): (2-5): (8-12).

(whitening and freckle-removing agent)

In one embodiment, the whitening and freckle-removing agent comprises 15-20 parts by weight of tranexamic acid, 10-30 parts by weight of nicotinamide, 0.5-1 part by weight of schizosaccharomyces cerevisiae fermentation product lysate, 5-10 parts by weight of rice fermentation product filtrate and 0.5-1 part by weight of glabridin.

In a preferred embodiment, the whitening and freckle-removing agent comprises 20 parts by weight of tranexamic acid, 30 parts by weight of nicotinamide, 1 part by weight of yeast fermentation product lysate of schizosaccharomyces, 10 parts by weight of rice fermentation product filtrate and 1 part by weight of glabridin.

In the invention, the Tranexamic acid is also named tranoxamic acid (Tranexamic acid) and Tranexamic acid, the chemical name of the Tranexamic acid is trans-4-aminomethyl cyclohexanecarboxylic acid, and white crystalline powder is prepared; no smell, slightly bitter taste. Is easily soluble in water and hardly soluble in ethanol, acetone, chloroform or diethyl ether. Molecular formula C₈H₁₅NO₂CAS number 1197-18-8, molecular weight 157.21 at 1 standard atmosphere, density 1.095g/cm³The melting point was 233 ℃ and the boiling point was 300.2 ℃.

In one embodiment, the tranexamic acid is purchased from Shanghai Violet Pont biomedical corporation, Inc.

In the present invention, nicotinamide (niacinamide), also called nicotinamide, is an amide compound of nicotinic acid. A crystalline powder that is white; no or almost no odor, bitter taste; it is slightly hygroscopic. It is easily soluble in water or ethanol, and soluble in glycerol. Chemical formula C₆H₆N₂O, molecular weight 122.13, CAS number 98-92-0.

In one embodiment, the nicotinamide is purchased from cypress chemical company, ltd.

In one embodiment, the mass ratio of niacinamide to glabridin is (20-30): 1; preferably, the mass ratio of the nicotinamide to the glabridin is 30: 1.

the tranexamic acid and the nicotinamide are used as whitening and freckle-removing components, the activity of the tyrosinase is inhibited, the oxidation reaction in the melanogenesis process is inhibited, the expression and transfer of melanogenesis-related protein are inhibited, and the formation of the melanogenesis and the freckles is inhibited in a multi-aspect synergistic manner. Particularly, the glabridin and the nicotinamide have a compound synergistic effect, and the whitening effect is more obvious when the glabridin and the nicotinamide are matched together.

In the present invention, the lysate of the fermentation product of the binary split yeast is a chemical substance, and the CAS number is 96507-89-0. Is prepared from Bifidobacterium through culturing, deactivating and decomposing to obtain metabolite, cytoplasm segment, cell wall component and polysaccharide complex. The lysate of the yeast fermentation product has strong anti-immunosuppression activity, can promote DNA repair, can effectively protect skin from being damaged by ultraviolet rays, is used for skin care, sun protection and after-sun care products of emulsion, water-based and hydroalcoholic systems, and helps to prevent photoaging of epidermis and dermis. The yeast fermentation product lysate can generate small molecules which comprise vitamin B group, minerals, amino acids and the like and are beneficial to skin care, and the yeast essence is high-quality yeast essence only used for skin care. It has effects in promoting metabolism of stratum corneum, capturing free radicals, inhibiting lipid peroxidation, whitening skin, and resisting aging. The product is rich in nutrients, and has skin nourishing effect.

In one embodiment, the split yeast fermentation product lysate is purchased from cypress chemical company, ltd.

In the invention, the rice fermentation product filtrate is a natural rice bran fermentation product, has the whitening effect, and can inhibit the growth of melanin and the activation of the tyrosinase. But the generation of cholesterol and ceramide is promoted, the cholesterol and the ceramide are important components of sebum, and the increase of the content of the cholesterol and the ceramide is helpful for improving the skin softness, so the cholesterol and the ceramide have the conditioning effect; has effects of activating glutathione reductase, improving skin activity and resisting aging.

In one embodiment, the rice fermentation product filtrate is of the brand number

XGN, purchased from New chemical industries, Inc.

In the invention, the glabridin is a flavonoid substance and is extracted from a precious plant called glabrous licorice, and the glabridin is known as whitening gold because of the strong whitening effect, can eliminate free radicals and muscle bottom melanin and is a whitening and anti-aging holy substance for skin. The molecular formula is as follows: c₂₀H₂₀O₄CAS number: 59870-68-7. It has strong anti-free radical oxidation effect in cytochrome P450/NADPH oxidation system, and can obviously inhibit free radicals generated in vivo metabolism process to prevent oxidation-sensitive biological macromolecules (low density lipoprotein LDL)DNA) and cell walls, etc. are damaged by free radical oxidation. Thereby preventing and treating certain pathological changes related to free radical oxidation, such as atherosclerosis, cell aging and the like. In addition, glabridin has certain functions of lowering blood fat and lowering blood pressure.

In one embodiment, the glabridin is purchased from oxsnow chemical, inc.

The composition for improving skin color provided by the invention adopts tranexamic acid and nicotinamide as whitening and freckle-removing components, inhibits the activity of tyrosinase, inhibits the oxidation reaction in the melanogenesis process, inhibits the expression and transfer of melanogenesis-related protein, and synergistically inhibits the formation of melanin and pigmented spots in multiple aspects.

(plant extract)

In one embodiment, the plant extract comprises one or more of magnolia sieboldii extract, mulberry root extract, undaria pinnatifida extract, hypsizygus marmoreus callus culture filtrate; preferably, the plant extract includes magnolia sieboldii extract, mulberry root extract and undaria pinnatifida extract.

In a preferred embodiment, the plant extract comprises 1 part by weight of magnolia sieboldii extract, 0.01 part by weight of undaria pinnatifida extract and 1 part by weight of mulberry root extract.

In the invention, the magnolia sieboldii extract is extracted from flowers and branches of magnolia sieboldii, is a component with a whitening effect, and can be used as a skin conditioner.

In one embodiment, the magnolia sieboldii extract is purchased from baihabo corporation.

The undaria pinnatifida extract is a pure natural surfactant, has excellent oxidation resistance, antibacterial property, anti-inflammatory property and dispersing capacity, and is used as a skin conditioner and a skin protective agent.

In one embodiment, the undaria pinnatifida extract is purchased from oxsnow chemical ltd, guangzhou.

In the invention, the mulberry root extract contains a plurality of effective substances such as mulberroside and the like, can powerfully take out free radicals, inhibit tyrosinase activity, inhibit indirect melanin formation, effectively relieve pressure and keep a pleasant mood.

In one embodiment, the mulberry root extract is purchased from clariant corporation.

According to the whitening and freckle-removing essence, the magnolia sieboldii extract, the undaria pinnatifida extract and the mulberry root extract are compounded, the whitening effect is more obvious by utilizing the synergistic effect of the plant extracts, the whitening and freckle-removing essence can effectively achieve the whitening and freckle-removing effect, can improve the effect of a whitening and freckle-removing agent, and has excellent stability and long-term improvement on the quality of skin.

Moisture-retaining agent

In one embodiment, the humectant is selected from betaine, glycerin, butylene glycol, propylene glycol, sorbitol, polyethylene glycol, sodium lactate, sodium pyrrolidone carboxylate; preferably, the humectant is betaine.

In the invention, the betaine is an alkaloid, the chemical name of the betaine is 1-carboxyl-N, N, N-trimethyl glycine lactone, the chemical structure of the betaine is similar to that of amino acid, the betaine belongs to a quaternary ammonium base substance, and the molecular formula of the betaine is C₅H₁₁NO₂. The raw powder was fluid and was a slightly brown powder. The melting point is 293 ℃. Is very soluble in water and methanol.

In one embodiment, the betaine is present in an amount of 8 to 12 parts by weight; preferably, the betaine is 10 parts by weight.

In one embodiment, the betaine is purchased from cypress chemical company, ltd.

The addition of betaine can improve the moisturizing effect and stability of the composition for improving skin color.

In one embodiment, the composition for improving skin color further comprises sodium metabisulfite, dipotassium glycyrrhizinate, distilled water; preferably, the composition for improving skin color also comprises 0.4 to 0.6 part of sodium metabisulfite, 0.5 to 0.8 part of dipotassium glycyrrhizinate and 25 to 60 parts of distilled water in parts by weight.

In a preferred embodiment, the composition for improving the skin color comprises 31 to 62 parts by weight of a whitening and freckle-removing agent, 2 to 5 parts by weight of a plant extract, 8 to 12 parts by weight of a humectant, 0.4 to 1.0 part by weight of sodium metabisulfite, 0.5 to 0.8 part by weight of dipotassium glycyrrhizinate and 25 to 60 parts by weight of distilled water; more preferably, the composition for improving the skin color comprises 47.6 parts by weight of a whitening and freckle-removing agent, 2.1 parts by weight of a plant extract, 10 parts by weight of a humectant, 0.5 part by weight of sodium metabisulfite, 0.8 part by weight of dipotassium glycyrrhizinate and 42 parts by weight of distilled water.

(sodium metabisulfite)

In the present invention, the sodium metabisulfite is also called sodium sulfate (Na)₂S₂O₅) Is white or yellow crystalline powder or small crystal with strong SO₂Smell, specific gravity 1.4, water solubility, acidity of aqueous solution, and SO evolution when contacting strong acid₂While the corresponding salts are generated and oxidized into Na when being placed in the air for a long time₂S₂O₆Therefore, the product cannot be stored for a long time. Above 150 ℃ SO is decomposed₂. CAS number 7681-57-4.

(dipotassium glycyrrhizinate)

In the invention, the dipotassium glycyrrhizinate is white or off-white fine powder, has the purity of 98 percent, has special sweet taste, good water solubility and pure mouthfeel. The dipotassium glycyrrhizinate has multiple effects of bacteriostasis, inflammation diminishing, detoxification, anti-allergy, deodorization and the like. Has wide application in the industries of medicine, cosmetics, daily chemicals, food and the like. CAS number: 68797-35-3, formula: c₄₂H₆₀K₂O₁₆。

The dipotassium glycyrrhizinate as antiallergic agent can be used together with sodium metabisulfite to inhibit oxidation reaction, improve stability, and prevent anaphylaxis due to nicotinic acid in nicotinamide.

In one embodiment, the composition for improving skin color is prepared by: sequentially adding betaine, plant extract, cracked yeast fermentation product lysate and rice fermentation product filtrate into distilled water, and uniformly stirring; adding nicotinamide, tranexamic acid, sodium metabisulfite, dipotassium glycyrrhizinate and glabridin, and stirring to obtain the composition for improving skin color.

The applicant unexpectedly finds that the betaine, the plant extract, the schizosaccharomyces cerevisiae fermentation product lysate and the rice fermentation product filtrate are sequentially added into the distilled water, so that the content of skin melanin can be further reduced, the skin melanin whitening effect is achieved, and the skin whitening effect can be kept for a long time by adding nicotinamide, tranexamic acid, sodium metabisulfite, dipotassium glycyrrhizinate and glabridin subsequently, more importantly, the stability of the whitening and freckle removing essence is improved, the skin whitening and freckle removing essence is free of layering phenomenon after being placed at 48 ℃ for 30 days, and is free of solidification phenomenon after being placed at-18 ℃ for 30 days.

Aqueous phase component

In one embodiment, the water phase component comprises 0.2-0.6 part of thickening agent, 2-5 parts of glycerin, 1-3 parts of butanediol, 0.02-0.1 part of sodium hyaluronate and 75-90 parts of water in parts by weight; preferably, the water phase component comprises 0.45 part of thickening agent, 3 parts of glycerin, 1 part of butanediol, 0.03 part of sodium hyaluronate and 82 parts of water in parts by weight.

(thickening agent)

In one embodiment, the thickener is selected from one or more of hydroxyethylcellulose, xanthan gum, carbomer; preferably, the thickener comprises hydroxyethyl cellulose, xanthan gum, carbomer.

In one embodiment, the thickener comprises 0.1 part by weight of hydroxyethyl cellulose, 0.1 part by weight of xanthan gum, and 0.25 part by weight of carbomer.

In the present invention, the hydroxyethyl cellulose is represented by the formula (C)₂H₆O₂)_nIt is a white or light yellow, tasteless and non-toxic fibrous or powdery solid, and is prepared by etherification reaction of alkali cellulose and ethylene oxide (or chloroethanol), belonging to non-ionic soluble cellulose ether. The hydroxyethyl cellulose has the characteristics of good thickening, suspending, dispersing, emulsifying, binding, film forming, moisture protection, protective colloid supply and the like. The viscosity change is small in the pH range of 2 to 12, but the viscosity decreases beyond this range. Has the functions of thickening, suspending, binding, emulsifying, dispersing, retaining water, protecting colloid, etc. Solutions of different viscosity ranges can be prepared. Is unstable at normal temperature and pressure, avoids humidity, heat and high temperature, and has abnormality on dielectric mediumGood salt solubility, and allows the salt to be contained in a high concentration in the water solution without change. Molar degree of substitution (m.s): 1.8-2.0, CAS number 9004-62-0.

In one embodiment, the hydroxyethyl cellulose is purchased from cypress chemical company, ltd.

The hydroxyethyl cellulose is used as a thickening agent, and has synergistic effect with xanthan gum and the like, so that the thickening agent provides a consistency with less pH influence for a system, has good skin feel and is beneficial to improving the stability of the system.

In the present invention, the xanthan gum, also known as xanthan gum, is an extracellular acidic heteropolysaccharide produced by fermentation of xanthomonas sp. Is prepared from D-glucose, D-mannose and D-glucuronic acid in a weight ratio of 2: 2: 1, the relative molecular mass of the polysaccharide polymer compound is more than 100 ten thousand. The secondary structure of xanthan gum is that the side chain winds around the main chain skeleton reversely, and a rodlike double-spiral structure is formed through a hydrogen bond system. It has unique rheological property, good water solubility, good stability to heat and acid and alkali, and good compatibility with various salts, and can be used as thickener, suspending agent, emulsifier, and stabilizer.

In one embodiment, the xanthan gum is of the brand name

XGN, purchased from New chemical industries, Inc.

The xanthan gum is reversely wound around the main chain skeleton due to the side chain, forms a rod-shaped double-spiral structure through a hydrogen bond system, can be used as a thickening agent, a suspending agent and an emulsifying agent, has a synergistic effect with hydroxyethyl cellulose and the like, provides a consistency with less pH influence for a system, has good skin feel and is beneficial to improving the stability of the system.

In one embodiment, the carbomer is carbomer U20.

In the invention, the carbomer U20 is an acrylate/C10-30 alkyl acrylate cross-linked copolymer, CAS No. 176429-87-1 is white loose powder, has high-efficiency thickening performance, high transparency, medium viscosity, strong suspension capacity, easy dispersion, high ion resistance and shear resistance, and can be quickly wetted.

In one embodiment, the carbomer U20 is purchased from lubrium corporation.

(Glycerol)

In the invention, the glycerin is colorless, transparent, odorless and viscous liquid, tastes sweet and has hygroscopicity. Mixing with water and alcohols, amines and phenols in any ratio, and making the aqueous solution neutral.

(sodium hyaluronate)

In the invention, the sodium hyaluronate has the chemical formula of (C)₁₄H₂₀NO₁₁Na) n, an inherent component in human body, is a glucan aldehyde acid, has no species specificity, and is widely present in tissues such as placenta, amniotic fluid, crystalline lens, articular cartilage, skin dermis and the like; it is distributed in the cytoplasm and the intercellular substance of the organ, and plays a role in lubricating and nourishing the cells and the organelles contained therein. Sodium hyaluronate belongs to high molecular polymer and has strong lubricating feeling and film forming property. The skin care product containing sodium hyaluronate has obvious lubrication feeling and good hand feeling when being smeared. After being applied to the skin, a layer of film can be formed on the surface of the skin, so that the skin can generate good smooth feeling and moist feeling, and the protective effect on the skin is achieved.

In one embodiment, the sodium hyaluronate is available under the trade designation Hybloom sodium hyaluronate (HA-T) and purchased from Huaxi Biotech.

(Water)

In the invention, the water is deionized water.

In one embodiment, the aqueous phase component is prepared by: adding the thickener into sixteen-in-one water, dispersing and stirring, fully swelling, putting into an emulsifying pot, sequentially adding the rest water, glycerol, butanediol and sodium hyaluronate, heating to 80-85 ℃, stirring and homogenizing to completely dissolve the water phase component, and thus obtaining the water phase component.

Oil phase component

In one embodiment, the oil phase component comprises, by weight, 0.25 to 0.35 parts of jojoba oil, 0.25 to 0.35 parts of synthetic squalane, 0.8 to 1.2 parts of olive oil PEG-7 esters, 0.8 to 1.2 parts of hydrogenated castor oil, and 0.08 to 0.12 parts of tocopherol acetate.

In a preferred embodiment, the oil phase component comprises, by weight, 3 parts of jojoba oil, 0.3 part of synthetic squalane, 1 part of olive oil PEG-7 esters, 1 part of hydrogenated castor oil, and 0.1 part of tocopherol acetate.

(Jojoba oil)

In the invention, the jojoba oil comprises the following components: minerals, vitamins, proteins, collagen, vegetable waxes, mytidic Acid traits: yellow, extracted from jojoba. Has very moistening effect, has the special oil fragrance of the Heba, and has light oil which is similar to the oil secreted by the sebaceous glands. Jojoba oil is also rich in vitamin D and proteins, is a good moisturizing and moisturizing oil, can maintain skin moisture, prevent wrinkles and soften skin, is suitable for mature and aged skin, and is commonly used for face and body massage and hair care. The chemical molecular arrangement is very similar to that of human sebum and is very easily assimilated and assimilated by the skin. It is strictly speaking a waxy texture rather than a liquid texture and will coagulate on cooling and will melt immediately upon contact with the skin and be absorbed by the skin. Jojoba oil has a light flavor and is an aromatherapy oil having a good efficacy even when used alone, and has been used as the best facial oil by professional aromatherapy practitioners. It has excellent moisturizing and nourishing effects, can increase skin moisture, prevent wrinkles and aging, also can soften hair and massage scalp, can help hair growth and hair care, but is most commonly used for caring facial skin due to its high price. Is suitable for all skin types, especially dry, rough, dull, oily and whelk skin types. The skin care cream has excellent permeability and high temperature resistance, the molecular arrangement is very similar to that of human sebum, and the skin care cream has very obvious skin care effect. Can be used for smoothing pores, regulating oil secretion of oily or mixed skin, and improving skin inflammation and sensitivity, eczema, psoriasis, and pimple. It has excellent moistening and moistening effects, and can increase skin moisture, prevent wrinkle and aging, soften hair, massage scalp, and promote hair growth and hair care. Jojoba oil has good hydrophilicity, and has moisture regulating effect on skin. But solidifies at low temperatures.

In one embodiment, the jojoba oil is purchased from leimada fine chemicals, inc.

The jojoba oil is used as a humectant, and is combined with synthesized squalane and betaine, so that the moisturizing effect is improved, the stability of the system is improved, and the jojoba oil cannot be solidified at a lower temperature.

(Synthesis of squalane)

In the invention, the synthesized squalane is hydrogenated polyisobutene, is colorless, tasteless and nontoxic liquid isomeric straight-chain alkane with high purity, and can be used for oil phase components of cosmetics and medicines without special limitation; compared with white mineral oil and vaseline, the synthetic squalane can provide a product with excellent and noble hand feeling, and has the advantages of moistening without greasiness, moisture retention and lubrication, and strong permeability; the nature of the squalane is very similar to that of natural squalane, but the price is much cheaper; the heat stability and the storage stability are good, and the emulsion is easy to emulsify when in use; has no irritation and allergy. The synthesized squalane is used as a humectant, and has combined action with betaine and jojoba oil, so that the moisturizing effect is improved, the stability of a system is also improved, the water solubility of the synthesized squalane is further improved, and the synthesized squalane is combined with tocopheryl acetate, olive oil PEG-7 esters and PEG-40 hydrogenated castor oil, so that the oxidation of the jojoba oil, squalane and the like is avoided, and the high-temperature stability is good.

The synthesized squalane is used as a humectant, and has combined action with betaine and jojoba oil, so that the moisturizing effect is improved, the stability of a system is also improved, the water solubility of the synthesized squalane is further improved, and the synthesized squalane is combined with tocopheryl acetate, olive oil PEG-7 esters and PEG-40 hydrogenated castor oil, so that the oxidation of the jojoba oil, squalane and the like is avoided, and the high-temperature stability is good.

In one embodiment, the synthetic cantharis squalane is purchased from Guangzhou Yuezze chemical Co.

(Olive oil PEG-7 esters)

In the invention, the olive oil PEG-7 esters are used as a softening agent, an emulsifying agent and a humectant in cosmetics. It is an emulsifier, has super strong emulsifying capacity, has clear and moist skin feel, is particularly suitable for high-grade cream and water-soluble olive oil derivatives, and is a good emollient and emulsifier.

In one embodiment, the olive oil PEG-7 esters are purchased from guangzhou shoghai biotechnology limited.

(hydrogenated Castor oil)

In one embodiment, the hydrogenated castor oil is selected from one or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PEG-80 hydrogenated castor oil; preferably, the hydrogenated castor oil is PEG-40 hydrogenated castor oil, available from New Enhan chemical trade company, Foshan.

In the invention, the PEG-40 hydrogenated castor oil is a modified castor oil product which is easy to decompose and does not have residue. The modified castor oil product is easy to decompose in nature and has no residue. PEG-40 hydrogenated castor oil (CO 40 for short) is a commonly used high-efficiency solubilizer, and can uniformly disperse oily substances such as essence, essential oil and the like into water to form a stable and transparent solution.

(PEG-40 hydrogenated castor oil, CO40) contains dioxane, and the addition amount needs to be noticed in use, and the limit is temporarily set to be not more than 30ppm in the bulletin of national food and drug administration for dioxane limit value in cosmetics at 6 months 2 in 2012.

(Tocopherol acetate)

In the invention, the tocopherol is a hydrolysate of vitamin E, and the natural tocopherol is d-tocopherol (dextrorotation type), which has 8 isomers such as alpha, beta, gamma, delta and the like, wherein the activity of the alpha-tocopherol is strongest. The tocopherol mixed concentrate (d-mixed-tocopherol concentrate) used as an antioxidant is a mixture of various isomers of natural tocopherol. The tocopherol has wide application in whole milk powder, cream or margarine, meat products, aquatic products, dehydrated vegetables, fruit juice beverages, frozen foods, instant foods and the like, and especially has important significance as an antioxidant and a nutrition enhancer of infant foods, curative effect foods, fortified foods and the like. Increasing cell antioxidation, and maintaining and promoting reproductive function. Has anti-aging effect, and can improve lipid metabolism, prevent arteriosclerosis, and reduce blood lipid.

In one embodiment, the tocopherol acetate is purchased from beijing beiLeililai daily chemical Co.

The tocopherol acetate belongs to a derivative of vitamin E, is commonly used as an antioxidant in cosmetics, has good antioxidant effect, is an oil-soluble natural substance, is a good nutritional moistening agent for skin, can prevent rancidity oxidation of oil and stabilize the oil when added into a care product. The composition has good effects in moisturizing and maintaining connective tissues, and protecting skin from ultraviolet rays, and can soften skin touch and retain skin moisture, promote wound healing, prevent inflammation, prevent skin from rough and chapped, improve black spots, and has a low safety risk index, thus being widely used. The tocopherol acetate is used as an antioxidant in the oil phase to prevent jojoba oil, squalane and the like from being oxidized, and the tocopherol acetate and sodium metabisulfite act together to improve the high-temperature stability of the system.

In one embodiment, the whitening and freckle-removing essence further comprises polyhydric alcohol and a preservative.

In a preferred embodiment, the whitening and freckle-removing essence further comprises 32 parts by weight of polyol and 0.4 part by weight of preservative.

Polyhydric alcohols

In one embodiment, the polyol is selected from one or more of 1, 2-butanediol, 1, 2-pentanediol, 1, 2-hexanediol, 1, 3-propanediol, glycerol; preferably, the polyhydric alcohol is a mixture of 1, 2-butanediol, 1, 2-pentanediol, and 1, 2-hexanediol.

In a preferred embodiment, the weight parts of the 1, 2-butanediol, 1, 2-pentanediol and 1, 2-hexanediol are 2 parts, 0.6 part and 0.6 part respectively.

(1, 2-butanediol)

In the present invention, the 1, 2-butanediol can be used as a cosmetic moisturizer and solvent, CAS No.: 26171-83-5.

(1, 2-pentanediol)

In the invention, the 1, 2-pentanediol has a chemical formula of C₅H₁₂O₂Can be dissolved in organic solvents such as alcohol, ether and ethyl acetate, and is often applied to cosmetic solvents. CAS number 5343-92-0.

(1, 2-hexanediol)

In the present invention, the 1, 2-hexanediol has a molecular formula C₆H₁₄O₂And a molecular weight of 118.17. A colorless transparent liquid. Has mild sweet flavor. Dissolving in water, ethanol, ether, and low-carbon aliphatic hydrocarbon. Can be used as solvent, perfume, and medical disinfectant. Acetone is condensed to obtain diacetone alcohol, and the diacetone alcohol is subjected to liquid phase hydrogenation to obtain the product. CAS number: 107-41-5.

The 1, 2-butanediol, 1, 2-pentanediol and 1, 2-hexanediol are compounded to be used as a solvent, the solubility of the jasminon and the neonicotin is good, and the 1, 2-butanediol has a moisturizing effect and acts together with the jasminon, so that the irritation of the system is reduced.

Preservative

In the invention, the preservative is jasminorange ketone and/or PE 9010; preferably, the preservative is indomethazone, purchased from Baistechman chemical Co., Guangzhou.

In the invention, the menthone, the anticorrosion synergist, the antioxidant, the anti-irritation, the emulsion stabilizer and the product protective agent are adopted.

The traditional preservative has a plurality of potential dangers in the facial mask, is relatively safe at a certain adding amount due to the fact that the types of the selectable preservatives are very limited, and shows obvious irritability such as itching, stabbing pain and burning sensation when the adding amount is more than 0.1% -0.2%, so that rough skin becomes sensitive muscle, and skin aging is accelerated over time. The same products as shinxinxianone (p-hydroxyacetophenone) exist in Lampayahieronymi (herbal medicine, native to Latin America) and Rubuschamaemorus (cloudberry, grown in alpine belts), and have antioxidant, tolerance-increasing, emulsion-stabilizing and broad-spectrum preservative capabilities. Has good water solubility, overcomes the defect that a plurality of preservatives or preservative substitute products are not easy to add, and has irritation resistance.

In one embodiment, the oil phase component is prepared by: taking jojoba oil, synthetic squalane, olive oil PEG-7 esters, PEG-40 hydrogenated castor oil and tocopherol acetate, and heating and stirring to completely dissolve the jojoba oil, the synthetic squalane, the olive oil PEG-7 esters, the PEG-40 hydrogenated castor oil and the tocopherol acetate to obtain the oil phase component.

a. preparing an aqueous phase component;

b. preparing an oil phase component;

e. preparation of a composition for improving skin color;

In one embodiment, the preparation method of the whitening and freckle-removing essence comprises the following steps:

a. preparation of the aqueous phase component: adding the thickening agent into sixteen-in-one water, dispersing and stirring, putting into an emulsifying pot after full swelling, sequentially adding the rest water, glycerol, butanediol and sodium hyaluronate, heating to 83 ℃, stirring and homogenizing to completely dissolve;

b. preparation of oil phase components: taking jojoba oil, synthetic squalane, olive oil PEG-7 esters, PEG-40 hydrogenated castor oil and tocopherol acetate, heating and stirring to completely dissolve the jojoba oil, the synthetic squalane, the olive oil PEG-7 esters, the PEG-40 hydrogenated castor oil and the tocopherol acetate;

c. adding the oil phase component into the water phase component, homogenizing and emulsifying, stirring, cooling to 60 deg.C, adding triethanolamine to adjust system pH to 6-6.8 to obtain mixture 1;

d. dissolving menthone with polyalcohol, heating to 50 deg.C for dissolving completely, and adding into mixture 1 to obtain mixture 2;

e. preparation of a composition for improving skin color: sequentially adding betaine, Undaria pinnatifida extract, Magnolia sieboldii extract, Morus alba extract, Schizophyllum commune fermentation product lysate and rice fermentation product filtrate into distilled water, and stirring; adding nicotinamide, tranexamic acid, sodium metabisulfite, dipotassium glycyrrhizinate and glabridin, and stirring;

The skin-color-improving composition is prepared by a specific method, the thickening agent is added into sixteen-in-one water for dispersion and stirring, the mixture is put into an emulsifying pot after being fully swelled, the rest water, the glycerol, the butanediol and the sodium hyaluronate are sequentially added, the mixture is heated to 83 ℃, and the emulsifying component is prepared by stirring and homogenizing the mixture to be completely dissolved, so that the skin-color-improving composition can obviously reduce the content of skin melanin and has the effects of whitening and lightening the skin melanin. The skin color becomes white and obvious.

The present invention will be specifically described below by way of examples. It should be noted that the following examples are only for illustrating the present invention and should not be construed as limiting the scope of the present invention, and that the insubstantial modifications and adaptations of the present invention by those skilled in the art based on the above disclosure are still within the scope of the present invention.

In addition, the starting materials used are all commercially available, unless otherwise specified.

Examples

Example 1

Embodiment 1 provides a whitening and freckle-removing essence, which comprises the following components: a composition for improving skin color, a water phase component, an oil phase component, a polyol, a preservative; the composition for improving skin color, the water phase component, the oil phase component, the polyhydric alcohol and the preservative in a mass ratio of 10: 84.25: 27: 7.2: 0.4;

the composition for improving the skin color comprises, by weight, 20 parts of tranexamic acid, 30 parts of nicotinamide, 1 part of a schizosaccharomyces cerevisiae fermentation product lysate, 10 parts of a rice fermentation product filtrate, 0.8 part of glabridin, 1 part of a magnolia sieboldii extract, 0.1 part of an undaria pinnatifida extract, 1 part of a mulberry root extract, 10 parts of betaine, 0.5 part of sodium metabisulfite, 0.8 part of dipotassium glycyrrhizinate and 42 parts of distilled water; the tranexamic acid is purchased from Shanghai purple Bob biological medicineLimit company; the nicotinamide was purchased from cypress chemical company, ltd; the two split yeast fermentation product lysate purchased from cypress chemical company; the rice fermentation product filtrate has the brand number of

XGN, purchased from New chemical industries, Inc.; the glabridin is purchased from Orxue chemical Co., Ltd, Guangzhou city; the Magnolia sieboldii extract was purchased from Baihabo corporation; the Undaria pinnatifida extract is purchased from Auxue chemical Co., Ltd, Guangzhou; the mulberry root extract is purchased from clariant corporation; the betaine is purchased from cypress chemical company, ltd; the CAS number of the sodium metabisulfite is 7681-57-4; the glycyrrhizic acid dipotassium CAS number 68797-35-3;

the water phase components comprise, by weight, 0.1 part of hydroxyethyl cellulose, 3 parts of glycerol, 1 part of butanediol, 0.1 part of xanthan gum, 200.25 parts of carbomer, 0.3 part of sodium hyaluronate and 82 parts of water; the hydroxyethyl cellulose was purchased from cypress chemical company, ltd; the xanthan gum is of the grade

XGN, purchased from New chemical industries, Inc.; the sodium hyaluronate is Hybloom sodium hyaluronate (HA-T) and purchased from Huaxi Biotech company;

the oil phase components comprise, by weight, 0.3 part of jojoba oil, 0.3 part of synthetic squalane, 1 part of olive oil PEG-7 esters, 1 part of hydrogenated castor oil and 0.1 part of tocopherol acetate; the jojoba oil was purchased from Guangzhou Limeda Fine chemical Co., Ltd; the synthetic squalane was purchased from Guangzhou Yuezze chemical Co., Ltd; the olive oil PEG-7 esters were purchased from guangzhou capacitive sea biotechnology limited; the hydrogenated castor oil is PEG-40 hydrogenated castor oil and is purchased from chemical trade company of Xinan of Foshan; the tocopherol acetate was purchased from Beijing Beiliei daily chemical Co., Ltd;

the polyalcohol is a mixture of 1, 2-butanediol, 1, 2-pentanediol and 1, 2-hexanediol; the weight parts of the 1, 2-butanediol, the 1, 2-pentanediol and the 1, 2-hexanediol are respectively 2 parts, 0.6 part and 0.6 part;

the preservative is xinxian ketone, purchased from Baiste chemical Co., Ltd, Guangzhou.

The preparation method of the whitening and freckle-removing essence comprises the following steps:

d. dissolving menthocamphorate with 1, 2-butanediol, hexanediol, and pentanediol, heating to 50 deg.C for dissolving completely, and adding into mixture 1 to obtain mixture 2;

Example 2

Example 2 provides a whitening and spot-removing essence, which is the same as example 1 except that the composition for improving skin color comprises, by weight, 20 parts of tranexamic acid, 30 parts of nicotinamide, 1 part of a diaschisis yeast fermentation product lysate, 10 parts of a rice fermentation product filtrate, 1 part of glabridin, 2 parts of magnolia sieboldii extract, 0.2 part of undaria pinnatifida extract, 1 part of a mulberry root extract, 10 parts of betaine, 0.5 part of sodium metabisulfite, 0.8 part of dipotassium glycyrrhizinate and 27 parts of distilled water.

The preparation method of the whitening and freckle-removing essence is the same as that of the example 1.

Example 3

Embodiment 3 provides a whitening and freckle-removing essence, which is the same as embodiment 1 except that the composition for improving skin color comprises 15 parts by weight of tranexamic acid, 10 parts by weight of nicotinamide, 0.5 part by weight of a schizosaccharomyces cerevisiae fermentation product lysate, 5 parts by weight of a rice fermentation product filtrate, 0.5 part by weight of glabridin, 1 part by weight of magnolia sieboldii extract, 0.5 part by weight of an undaria pinnatifida extract, 1 part by weight of a mulberry root extract, 10 parts by weight of betaine, 0.5 part by weight of sodium metabisulfite, 0.5 part by weight of dipotassium glycyrrhizinate and 58 parts by weight of distilled water.

Example 4

Embodiment 4 provides a whitening and freckle-removing essence, which is the same as embodiment 1 except that the composition for improving skin color comprises, by weight, 20 parts of tranexamic acid, 20 parts of nicotinamide, 1 part of a diaschisis yeast fermentation product lysate, 10 parts of a rice fermentation product filtrate, 1 part of glabridin, 1.5 parts of magnolia sieboldii extract, 0.2 part of undaria pinnatifida extract, 1.5 parts of a mulberry root extract, 10 parts of betaine, 0.5 part of sodium metabisulfite, 0.5 part of dipotassium glycyrrhizinate and 37 parts of distilled water.

a. preparation of the aqueous phase component: sequentially adding water, thickening agent, glycerol, butanediol and sodium hyaluronate, heating to 83 ℃, and stirring and homogenizing to completely dissolve;

Example 5

Example 5 provides a whitening and spot-removing essence, which is the same as example 1, except that the composition for improving skin color comprises, by weight, 1 part of magnolia sieboldii extract, 0.1 part of undaria pinnatifida extract, 1 part of mulberry root extract, 10 parts of betaine, 0.5 part of sodium metabisulfite, 0.8 part of dipotassium glycyrrhizinate and 42 parts of distilled water.

The preparation method of the whitening and freckle-removing essence is the same as that of the example 1, and is only different from the preparation of the composition for improving skin color: sequentially adding betaine, Undaria Pinnatifida extract, Magnolia Sieboldii extract, and Mori radix extract into distilled water, and stirring; adding sodium metabisulfite and dipotassium glycyrrhizinate, and stirring.

Example 6

Example 6 provides a whitening and spot-removing essence, which is the same as example 1 except that the composition for improving skin color comprises, by weight, 20 parts of tranexamic acid, 30 parts of nicotinamide, 1 part of a yeast dehiscent lysate, 10 parts of a rice fermentation product filtrate, 0.8 part of glabridin, 10 parts of betaine, 0.5 part of sodium metabisulfite, 0.8 part of dipotassium glycyrrhizinate and 42 parts of distilled water.

The preparation method of the whitening and freckle-removing essence is the same as that of the example 1, and is only different from the preparation of the composition for improving skin color: sequentially adding betaine, cracked yeast fermentation product lysate and rice fermentation product filtrate into distilled water, and uniformly stirring; adding nicotinamide, tranexamic acid, sodium metabisulfite, dipotassium glycyrrhizinate and glabridin, and stirring.

Example 7

Example 7 provides a whitening and freckle-removing essence, which is the same as example 4.

The preparation method of the whitening and freckle-removing essence is the same as that in example 4, and is only different from the preparation method of the water-phase component: sequentially adding water, thickener, glycerol, butanediol, and sodium hyaluronate, heating to 62 deg.C, stirring, and homogenizing to completely dissolve.

Performance testing

1. High-temperature stability: the whitening and freckle-removing essence liquid described in examples 1-7 was placed at 48 ℃ for 30 days, and whether or not the phenomenon of delamination occurred after 30 days was observed, and the test results are shown in table 1.

2. Low-temperature stability: the whitening and freckle-removing essence liquid described in examples 1-7 was placed at-18 ℃ for 30 days, and whether coagulation occurred after 30 days was observed, and the test results are shown in table 1.

TABLE 1

	48℃	-18℃
			Example 1	Without delamination	Without coagulation
Example 2	Without delamination	Without coagulation
			Example 3	Without delamination	Without coagulation
Example 4	Layering	Slightly solidified
			Example 5	Without delamination	Without coagulation
Example 6	Layering	Slightly solidified
			Example 7	Little delamination	Without coagulation

3. And (3) testing the whitening effect: 30 female volunteers with healthy skin (ITA ° values between 28 and 41) were selected and randomly divided into 6 groups of 5 persons; the whitening and freckle-removing essence liquids described in examples 1-7 were used once every night, continuously used for 4 weeks, and compared with the skin color difference before and after use by an instrument efficacy determination and self-evaluation method. Skin MI values were determined using a skin black and red pigment tester MX18 (CK, Germany); and the P value of the cooperation significance difference is analyzed, the P value is larger than 0.05, the significance difference does not exist, the P value is smaller than 0.01, and the test result is shown in a table 2.

TABLE 2

4. Self-evaluation: the results of 4-week observation of the whitening and freckle-removing essence liquids described in examples 1-7 are respectively used, and the evaluation criteria are as follows: the skin was visibly darkened 1, a little skin darkening was noted 2 when carefully observed, no apparent skin change was noted 3 when carefully observed, a little skin whitening was noted 4 when carefully observed, a little skin whitening was noted 5 when averaged, and the test results are shown in table 3.

TABLE 3

	Skin complexion changes
		Example 1	4.3
Example 2	4.6
		Example 3	4.1
Example 4	4.3
		Example 5	3.1
Example 6	3.2
		Example 7	3.4

5. Safety featureEvaluation: the irritation of the whitening and spot-removing essence described in example 2 was measured by chick embryo chorioallantoic membrane vascular test (CAMVA), and after the chick embryo was incubated up to 4d (incubation temperature: 37 ℃ C., humidity: 60%), 2-3mL of serum was taken out from the bottom by a syringe, the well was sealed with wax, and a window was opened (about 1 cm) above the chick embryo²) Sealing with a film, opening the window at 14d, placing into a resin ring, adding 40 μ L of the whitening and freckle-removing essence liquid described in example 2, and incubating in an incubator for 30min to observe bleeding and change. The samples are diluted by water to 70% and 100%, no positive reaction is found at 70%, 1 positive reaction appears in 3 chick embryos of 100% samples, so that 100% is adopted in subsequent formal experiments, 1 positive reaction appears in 10 chick embryos, RC50 (the concentration of the sample when half of chick embryos are positive) is calculated to be more than 100%, and the whitening and freckle-removing essence is non-irritant according to the judgment standard.

The foregoing examples are merely illustrative and serve to explain some of the features of the method of the present invention. The appended claims are intended to claim as broad a scope as is contemplated, and the examples presented herein are merely illustrative of selected implementations in accordance with all possible combinations of examples. Accordingly, it is applicants' intention that the appended claims are not to be limited by the choice of examples illustrating features of the invention. Also, where numerical ranges are used in the claims, subranges therein are included, and variations in these ranges are also to be construed as possible being covered by the appended claims.

Claims

1. The whitening and freckle-removing essence is characterized by comprising a composition for improving skin color, a water phase component and an oil phase component; the composition for improving skin color comprises a whitening and freckle removing agent, a plant extract and a humectant.

2. The whitening and freckle-removing essence according to claim 1, wherein the whitening and freckle-removing agent comprises 15-20 parts by weight of tranexamic acid, 10-30 parts by weight of nicotinamide, 0.5-1 part by weight of schizosaccharomyces cerevisiae fermentation product lysate, 5-10 parts by weight of rice fermentation product filtrate and 0.5-1 part by weight of glabridin.

3. The essence of claim 1, wherein the plant extract comprises one or more of magnolia sieboldii extract, mulberry root extract, undaria pinnatifida extract, and hypecol callus culture filtrate.

4. The essence of claim 1, wherein the composition for improving skin color further comprises sodium metabisulfite, dipotassium glycyrrhizinate and distilled water.

5. The essence with whitening and freckle removal functions of claim 4, wherein the composition for improving skin color comprises, by weight, 31-62 parts of a whitening and freckle removal agent, 2-5 parts of a plant extract, 8-12 parts of a humectant, 0.4-1.0 part of sodium metabisulfite, 0.5-0.8 part of dipotassium glycyrrhizinate and 25-60 parts of distilled water.

6. The whitening and freckle-removing essence according to claim 1, wherein the water phase component comprises, by weight, 0.2-0.6 part of a thickening agent, 2-5 parts of glycerin, 1-3 parts of butanediol, 0.02-0.1 part of sodium hyaluronate and 75-90 parts of water.

7. The whitening and freckle-removing essence according to claim 6, wherein the thickening agent is one or more of hydroxyethyl cellulose, xanthan gum and carbomer.

8. The whitening and freckle-removing essence according to claim 1, wherein the oil phase comprises, by weight, 0.25-0.35 parts of jojoba oil, 0.25-0.35 parts of synthetic squalane, 0.8-1.2 parts of olive oil PEG-7 esters, 0.8-1.2 parts of hydrogenated castor oil and 0.08-0.12 parts of tocopherol acetate.

9. The whitening and freckle-removing essence according to any one of claims 1 to 8, wherein the whitening and freckle-removing essence further comprises polyhydric alcohol and a preservative.

10. The preparation method of the whitening and freckle-removing essence according to claim 9 is characterized by comprising the following steps of:

a. preparing an aqueous phase component;

b. preparing an oil phase component;

e. preparation of a composition for improving skin color;