KR101077693B1 - Cosmetic composition containing xylitol and β-1,3-glucane for moisturizing effect on the skin - Google Patents

Abstract

The present invention relates to a skin moisturizing cosmetic composition containing xylitol and beta-1,3-glucan simultaneously. More specifically, the cosmetic composition for skin moisturizing of the present invention contains a combination of xylitol and beta-1,3-glucan, thereby exhibiting an excellent skin moisturizing effect.

Xylitol * Beta-1,3-Glucan * Skin Moisturizing * Cosmetic

Description

Cosmetic composition for moisturizing skin containing xylitol and beta-1,3-glucan {{Cosmetic composition containing xylitol and β-1,3-glucane for moisturizing effect on the skin}

1 is a graph showing the skin moisturizing effect in the human body of Examples and Comparative Examples of the present invention.

Figure 2 is a graph showing the skin recovery effect in the human body of the Examples and Comparative Examples of the present invention.

The present invention relates to a skin moisturizing cosmetic composition containing xylitol and beta-1,3-glucan simultaneously. More specifically, the cosmetic composition for skin moisturizing of the present invention contains a combination of xylitol and beta-1,3-glucan, thereby exhibiting an excellent skin moisturizing effect.

The skin is divided into three layers of epidermis, dermis, and subcutaneous fat tissue in order from the outside, and serves as a primary shield that protects the human body from the external environment. However, changes in external temperature and humidity, ultraviolet rays, and pollutants, as well as excessive physical and chemical stimuli, stress, and malnutrition from the outside seriously degrade normal functions such as moisturizing function of the skin, and aging of the skin. It promotes the phenomena and damages the skin. To prevent such phenomena and to maintain healthier and more beautiful skin, cosmetics contain bioactive substances from various animals, plants and microorganisms. There has been effort.

The skin carries about 70% of the body's water, which is a variety of bioactive substances required by the body. In addition, this moisture helps the skin to maintain a healthy state, and also plays an important role in properly controlling the evaporation of moisture in vitro. In addition, the epidermis is separated from the outside in the order of the stratum corneum, granule layer, polar layer, basal layer, the cells of the stratum corneum acts like a brick and the intercellular lipids between the stratum corneum acts as a mortar to form the skin barrier ( J. Invest.Drmatol. 80 (Suppl.), 44-49. 1983.

The stratum corneum of the epidermis having a thickness of about 20 μm contains about 10 to 20% of water and is present at the outermost part of the human body, thereby suppressing evaporation of water from the body. It also protects the skin by blocking excessive material penetration from the outside. The surface of these stratum corneum is covered with a thin, natural protective film made of sebum from the sebaceous glands and sweat from the glands to prevent evaporation of moisture. The cells constituting the stratum corneum have high concentrations of natural moisturizing factor (NMF), which are water-soluble ingredients, which help the skin to show flexibility and maintain proper moisture. The same substance is not only water soluble, but also effectively binds to moisture and inhibits the drying of moisture from the skin (J. Invest. Dermatol. 54, 24-31, 1970). However, artificial temperature control of cooling / heating according to changes in environment or life patterns, skin stress caused by various stresses and environmental pollution in social life, frequent skin washing due to makeup habits and natural aging due to age increase Due to various causes such as the decrease in moisture of the stratum corneum, the skin is dried, the surface is rough, and the skin loses luster, so that the appearance of dull appearance occurs, the need for a skin moisturizer is increasing.

To this end, a method of increasing moisture retention in the stratum corneum by using a humectant having a property of absorbing moisture or an occlusive moisturizer preventing moisture evaporation has been most widely used. Most of the humectants include polyols such as glycerin, propylene glycol, 1,3-butylene glycol, and polyethylene glycol. However, they have a drawback that is very sticky or heavy and damp due to the inherent viscosity and unique physical properties of the polyol when applied to the skin.

As a conventional moisturizer, a closed moisturizer is a lipid component such as ceramide or an essential fatty acid and lipid complex (J. Invest. Dermatol. (5), 731-740, 1994). There is a disadvantage in disturbing the stability to inhibit, and there is an disadvantage inadequate for producing a transparent gel-like product. In addition, formulations containing lamellar liquid crystals, which have been studied until recently, are known to have excellent moisture moisturizing properties with advantages similar to the skin keratin structure, but have limitations in that they can be used universally only in specific compositions of raw materials.

Accordingly, the present inventors have studied cosmetics composition to find a substance containing a large amount of moisture in the stratum corneum and reducing moisture evaporation, and as a result, xylitol in nature contains a large amount of moisture in the stratum corneum and reduces moisture evaporation, It is possible to prevent the living body from causing phenomena such as decrease in transparency of skin, roughness of skin, decrease of skin gloss and fine wrinkles caused by changes in environment, that is, temperature change, humidity decrease, and wind. I found it to be made. In addition, as a result of more in-depth study, when beta-1,3-glucan is applied together with the xylitol, the skin moisturizing effect is further enhanced and the present invention has been completed.

Therefore, it is an object of the present invention to provide a skin moisturizing cosmetic composition containing xylitol and beta-1,3-glucan as an active ingredient.

In order to achieve the above object, the skin moisturizing cosmetic composition of the present invention is characterized in that it contains xylitol and beta-1,3-glucan as an active ingredient. In addition, the cosmetic composition for moisturizing the skin according to the present invention is characterized by containing 0.001 to 10% by weight of xylitol and 0.001 to 10% by weight of beta-1,3-glucan based on the total weight of the composition.

Hereinafter, the present invention will be described in more detail.

Xylitol used in the present invention is obtained by a hydrogenation reaction based on xylose present in birch, corn, etc. as a plant-derived raw material. Although the method for producing xylitol is not particularly limited, for example, as described in US Patent No. 4008825, the xylose obtained mainly by hydrolyzing the xylan contained in the vegetable raw material is reduced in the presence of a catalyst to xylitol. There is a method of preparing by converting or producing xylitol by microorganisms, for example, as described in Japanese Patent Application Laid-open No. Hei 8-505522, xylitol can be produced from glucose using yeast. In the manufacturing method of xylitol using microorganisms using glucose as a raw material, the process involves relatively harsh conditions and risks such as hydrolysis of xylan contained in plant raw materials or hydrogenation of xylose using a metal catalyst. Xylitol can be produced without reducing the cost.

Meanwhile, beta-1,3-glucan, which is also used in the present invention, is a high-purity glucan having a purity of 98% or more obtained by liquid culture of Schizopyllum commune mycelium. Beta-1,3-glucan obtained by culturing yeast, barley and the like can be used.

The present invention contains xylitol and beta-1,3-glucan which are present in nature, and realizes excellent feeling without moisture and excellent stickiness.                     

Xylitol and beta-1,3-glucan of the present invention are each contained in an amount of 0.001 to 10% by weight based on the total weight of the composition, and preferably in an amount of 0.01 to 5% by weight. If the content of each component is less than 0.001% by weight, the effect is insignificant, and if the content of more than 10% by weight may cause problems in use.

The external composition for skin containing xylitol and beta-1,3-glucan of the present invention is not particularly limited in the formulation, for example, softening longevity, nourishing longevity, massage cream, nourishing cream, pack, gel or skin adhesion It may be a cosmetic composition having a formulation of type cosmetic, and may also be a transdermal formulation such as lotion, ointment, gel, cream, patch or spray.

Hereinafter, although an Example and a test example are given and this invention is demonstrated in detail, this invention is not limited only to these examples.

EXAMPLE 1 AND COMPARATIVE EXAMPLES 1-3

To Example 1 and Comparative Examples 1 to 3 were prepared in the composition shown in Table 1.

Ingredient (% by weight) Example 1 Comparative Example 1 Comparative Example 2 Comparative Example 3 Beads wax 2 2 2 2 Stearyl alcohol 3 3 3 3 Stearic acid 8 8 8 8 Squalene 10 10 10 10 Propylene Glycol Monostearate 3 3 3 3 Polyoxyethylene ether One One One One antiseptic Quantity Quantity Quantity Quantity Antioxidant Quantity Quantity Quantity Quantity glycerin 2 2 2 2 Propylene glycol 2 2 2 2 Butylene glycol 4 4 4 4 Sodium Polyacrylate 0.2 0.2 0.2 0.2 Purified water To 100 To 100 To 100 To 100 Xylitol 4.5 - 4.5 - Beta-1,3-glucan 4.5 - - 4.5 Carbomer Quantity Quantity Quantity Quantity

Test Example 1 Skin Moisturizing Test

The skin moisturizing power appeared when applied to the human body using Comparative Examples 1 to 3 and Example 1 was measured.

Twenty healthy males and females in their 20s and 30s were washed thoroughly and then waited for a certain time in constant temperature and humidity conditions (241 ℃, 40-50%). Next, the skin moisture content was measured before applying Comparative Examples 1 to 3 and Example 1 to the forearm site, and the skin moisture content was measured for 2, 4 and 6 hours after random application. Skin moisture content was measured using a corneometer (CeK) of Germany. For comparison, the paired T-test was used for statistical treatment compared to the untreated group. The results are shown in Figure 1 below.

As shown in FIG. 1, it was confirmed that Example 1 containing both xylitol and beta-1,3-glucan increased the human skin moisture most (paired T-test, p <0.05).

Test Example 2 Skin Recovery Test in Human Body

When the applied to the damaged skin using Comparative Examples 1 to 3 and Example 1, the skin recovery power appeared.

Twenty healthy males and females in their 20s and 30s were washed for a night before waiting for a period of time under constant temperature and humidity conditions (241 ℃, 40-50%). Next, after measuring the state before damaging the forearm region using the 3M cellophane tape, the state was measured immediately after artificially damaging the skin by stripping the forearm region 20 to 30 times. Next, after Comparative Examples 1-3 and Example 1 were randomly applied to the forearm site, skin recovery power of 3, 6 and 12 hours was measured. Skin recovery was measured using an evaporimeter from Swedish servomed. For comparison, statistical analysis was performed using paired T-test compared to untreated group. The results are shown in FIG. 2.

As shown in Figure 2, it was confirmed that Example 1 containing both xylitol and beta-1,3-glucan is the best skin recovery of the human body.

As described above, the cosmetic composition according to the present invention contains a large amount of moisture in the stratum corneum of the skin and contains xylitol and beta-1,3-glucan to show an excellent skin moisturizing effect so as to have an effect of reducing water evaporation. This can be useful.

Claims (3)

A cosmetic composition for moisturizing skin, comprising xylitol and beta-1,3-glucan. According to claim 1, wherein the composition is moisturizing cosmetic composition, characterized in that it contains 0.001-10% by weight of xylitol and 0.001-10% by weight of beta-1,3-glucan relative to the total weight of the composition. The composition of claim 1, wherein the composition has a formulation of softening cream, nourishing cream, massage cream, nourishing cream, pack, gel, essence, lipstick, makeup base, foundation, lotion, ointment, gel, cream, patch or spray Cosmetic composition for skin moisturizing, characterized in that.

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