KR100795877B1 - Cosmetic composition containing Honey Extract and Pumpkin Extract for moisturizing the skin - Google Patents

Abstract

The present invention relates to a skin moisturizing cosmetic composition that can improve skin dryness caused by aging, and more particularly, skin containing honey extracts rich in various sugars and pumpkin extracts rich in various vitamins as active ingredients. The present invention relates to a cosmetic composition having an excellent moisturizing effect. Cosmetic compositions containing the above components at the same time exhibits a very excellent effect on skin moisturizing as well as antioxidant effect.

Honey Extract, Pumpkin Extract, Polyol, Moisturizing Skin, Cosmetic Composition

Description

Cosmetic composition for skin moisturizing containing honey extract and pumpkin extract {Cosmetic composition containing Honey Extract and Pumpkin Extract for moisturizing the skin}

1 is a diagram showing the results of applying the cosmetic compositions of Examples 1 and 2 and Comparative Examples 1 to 4 after treatment with acetone on the back of young hairless mice as changes in TEWL (moisture evaporation amount).

2 is a diagram showing the results of applying the cosmetic compositions of Examples 1 and 2 and Comparative Examples 1 to 4 on the skin of a person with dry skin as a change in TEWL (moisture evaporation amount).

Figure 3 is a diagram showing the results of measuring the skin moisture content with a Koniometer for 24 hours after applying Examples 1 and 2 of the present invention once.

The present invention relates to a skin moisturizing cosmetic composition that can improve skin dryness caused by aging, and more particularly, skin containing honey extracts rich in various sugars and pumpkin extracts rich in various vitamins as active ingredients. The present invention relates to a cosmetic composition having an excellent moisturizing effect. Cosmetic compositions containing the above components at the same time shows an excellent effect on the skin moisturizing as well as antioxidant effect.

The skin is divided into three layers of epidermis, dermis and subcutaneous fat tissue in order from the outside, and serves to protect the human body from physical and chemical stimuli of the external environment. In particular, the skin carries about 65 to 70% of the body's moisture, which is the body's vital bioactive substance, and helps to keep the skin soft and moist. Play a role. In addition, the epidermis is separated from the outside in the order of the stratum corneum, granule layer, polar layer, basal layer, the cells of the stratum corneum acts like a brick and the intercellular lipids between the stratum corneum acts as a mortar to form a skin barrier. (J. Invest. Dermatol. 80 (Suppl.), 44-49. 1983). The stratum corneum of the epidermis contains about 10 to 20% of moisture and is present at the outermost part of the human body to suppress evaporation of moisture from the body, while blocking excess penetration of substances from the outside. The surface of these stratum corneum is covered with a thin, natural protective film made of sebum from the sebaceous glands and sweat from the glands to prevent evaporation of moisture. In other words, you can think of it as a form of wrapping a sponge (stratum corneum) with water wrapped in a plastic wrap (natural protective film) where water does not pass through. The cells constituting the stratum corneum have high concentrations of natural moisturizing factors (NMF), which are water-soluble ingredients, which help the skin to show flexibility and maintain proper moisture. The substance is not only water soluble, but also effectively binds to moisture and inhibits the drying of moisture from the skin (J. Invest. Dermatol. 54, 24-31, 1970). However, artificial temperature control of cooling / heating due to changes in environment or life patterns, skin stress caused by various stresses and environmental pollution in social life, and frequent skin washing due to makeup habits and age increase Due to various causes, such as a decrease in moisture in the stratum corneum, the skin is dried, the surface is rough, and the skin loses the luster, so that the appearance of dull appearance occurs, the need for a skin moisturizer is increasing.

Conventionally, a method of increasing water retention in the stratum corneum by using a humectant having a property of absorbing moisture or an occlusive moisturizer preventing moisture evaporation as a moisturizing agent has been most widely used. Most of the humectants include polyols such as glycerin, propylene glycol, 1,3-butylene glycol and polyethylene glycol. However, they have a disadvantage in that they are very sticky or damp due to the inherent viscosity and physical properties of the polyol when applied to the skin. As a closed moisturizer, lipid components such as ceramide, essential fatty acids and lipid complexes were used (J. Invest. Dermatol. (5), 731-740, 1994). There are disadvantages and disadvantages which are inadequate for producing products on transparent gels. In addition, formulations containing lamellar liquid crystals, which have been studied until recently, are known to have excellent moisture moisturizing properties with advantages similar to the skin keratin structure, but have problems in general use because they are possible only in specific compositions of raw materials.

Therefore, the present inventors have studied to find a composition that contains a large amount of water in the stratum corneum and reduces moisture evaporation, and as a result, a honey extract that contains a large amount of polysaccharides present in nature, and has excellent ability to carry and retain moisture, is used to extract moisture from the stratum corneum. It contains a large amount and reduces the evaporation of water, reducing the transparency of the skin caused by changes in the environment, that is, temperature changes, humidity decreases, wind, etc. caused by the lack of moisture in the stratum corneum, roughness of the skin, decrease in skin luster and It has been found that fine wrinkles can be prevented from appearing prominently, and also found that the effect is increased by containing a pumpkin extract rich in various vitamins, thereby completing the present invention. In addition, the addition of a polyol (polyol) to the composition was found that the effect is further enhanced to complete the present invention.

Accordingly, an object of the present invention is to contain a large amount of moisture in the stratum corneum and reduce the evaporation of water, thereby providing a very good skin moisturizing and safe skin moisturizing cosmetic composition that can prevent and improve various symptoms of skin caused by lack of moisture. To provide.

In order to achieve the above object, the present invention provides a cosmetic composition containing a mixture of honey extract and pumpkin extract as an active ingredient.

In addition, the present invention provides a cosmetic composition further comprising a polyol (polyol) in a composition containing the honey extract and pumpkin extract as an active ingredient.

Hereinafter, the present invention will be described in more detail.

The present invention relates to a cosmetic composition comprising a polyol, which is a pumpkin extract containing a large amount of polysaccharides present in nature, and excellent in water holding and holding ability, a pumpkin extract rich in various vitamins, and a moisturizing agent.

Hereinafter, in the present invention, a mixture of the honey extract, the pumpkin extract, and the polyol of the composition is named a 24-hour moisturizing complex I (24hr Moisturizing Complex I), and a mixture of the honey extract and the pumpkin extract is mixed with a 24-hour moisturizing agent II (24hr Moisturizing) It is called Complex II).

Honey is stored by converting the nectar and pollen collected from the flowers of several plants into their food. Two monosaccharides, glucose and fructose, carbohydrates, minerals, vegetable pigments, enzymes, Pollen and the like. More than 80% of honey's components are monosaccharides such as glucose and fructose. This ingredient has excellent hygroscopicity and forms a moisture film on the skin, which has a continuous moisturizing effect. Honey extract contains a large amount of these ingredients has a strong moisturizing effect.

Pumpkin extract is rich in various vitamins and minerals. These ingredients have powerful antioxidant effects, providing skin regeneration and skin protection. Pumpkin extracts are especially high in vitamins A and C. Vitamin A is effective in the prevention of dry skin and the spreading of hands and feet after kitchen work. Vitamin A, absorbed by the skin, promotes the differentiation and proliferation of skin cells, giving them elasticity, skin damaged by external environment such as ultraviolet light, skin diseases such as psoriasis, acne, and anti-aging ( collagen synthesis promotion) and the like. Vitamin C is known for its strong antioxidant activity and promoting collagen synthesis.It is known to inhibit tyrosinase's action on melanin formation in cells. Outstanding
Honey extract and pumpkin extract used in the present invention is extracted through a conventional extraction method well known in the art, for example, can be prepared by a conventional extraction method using water as a solvent. In addition, the honey extract and the pumpkin extract according to the present invention may be used commercially available products, for example, commercial products "Jeju Yuchae Honey Extract®" and "Gourd Infusion®" manufactured by extracting by cold and hot extraction method from Bioland Co., Ltd. Can be used. For reference, the commercial product "Jeju rapeseed honey extract®" is extracted by filtering with a filter press for 24 hours at 4 ℃ while stirring well 1kg of rapeseed honey extract of Jeju rapeseed 10 times by weight of water, "Gourd Infusion®" 1kg of silver zucchini was washed cleanly, added 10 times of water to the weight, stirred well and extracted at 4 ° C. for 28 hours, followed by filtration with a filter press.

Polyol is a humectant having an excellent water absorption effect and is commonly used as a moisturizer in cosmetic formulations, and includes glycerin, dipropylene glycol, propylene glycol, 1,3-butylene glycol, polyethylene glycol, and the like.

The 24-hour moisturizing complex according to the present invention is a combination of honey extract, pumpkin extract, and polyol in a combination based on scientific basic data on the skin. You can actually implement it. Cosmetic compositions using the same can be used in cosmetics for moisturizing the skin. In addition, the formulation is not particularly limited, and may be a flexible longevity, nourishing longevity, massage cream, nutrition cream, pack, gel, skin adhesive type cosmetics, or transdermal dosage form.

Hereinafter, the present invention will be described in more detail with reference to examples, but the scope of the present invention is not necessarily limited to these examples.

Experimental Example 1 Moisturizing Effect Experiment of 24hr Moisturizing Complex

In order to examine the moisturizing effect of the 24-hour moisturizing complex of the present invention, a 24-hour moisturizing agent I (24hr Moisturizing Complex I) having a ratio of 1: 1: 1 of honey extract, pumpkin extract and glycerin (Glycerin), respectively After 24 hours moisturizing agent II (24hr Moisturizing Complex II) prepared with only 1 and 1 honey extract and pumpkin extract, respectively, the moisturizing effect was examined. However, the usable range of each component is not limited only to this ratio.

The formulations in Table 1 below are emulsion (O / W) formulations, in weight percent.

division Raw material name Example 1 Example 2 Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Oily ingredients Stearic acid 1.0 1.0 1.0 1.0 1.0 1.0 Cetearyl Alcohol 0.2 0.2 0.2 0.2 0.2 0.2 Hydrogenated Oil 0.7 0.7 0.7 0.7 0.7 0.7 Lipophilic glyceryl stearate 0.5 0.5 0.5 0.5 0.5 0.5 Hydrogenated Lecithin / C12-16 Alcohol / Palmetic Acid 1.0 1.0 1.0 1.0 1.0 1.0 antiseptic 0.3 0.3 0.3 0.3 0.3 0.3 Polydecene 4.0 4.0 4.0 4.0 4.0 4.0 Meadowfoam seed oil 1.0 1.0 1.0 1.0 1.0 1.0 Pentaerythritol tetraisostearate 3.0 3.0 3.0 3.0 3.0 3.0 Dimethicone 0.5 0.5 0.5 0.5 0.5 0.5 Cetyloctanoate 2.0 2.0 2.0 2.0 2.0 2.0 Decyl cocoate 1.0 1.0 1.0 1.0 1.0 1.0 Cyclomethicone 3.0 3.0 3.0 3.0 3.0 3.0 Tocopheryl Acetate 0.1 0.1 0.1 0.1 0.1 0.1 Water component Purified water To 100 To 100 To 100 To 100 To 100 To 100 Butylene glycol 5.0 5.0 5.0 5.0 5.0 5.0 Disodium ID 0.02 0.02 0.02 0.02 0.02 0.02 Tee 0.15 0.15 0.15 0.15 0.15 0.15 antiseptic 0.2 0.2 0.2 0.2 0.2 0.2 24hr Moisturizing Complex I (Honey Extract: Pumpkin Extract: Glycerin = 1: 1: 1: 1) 5.0 - - - - - 24hr Moisturizing Complex II (Honey Extract: Pumpkin Extract = 1: 1) - 5.0 - - - - Honey extract - - 5.0 - - - Pumpkin Extract - - - 5.0 - - Glycerin - - - - 5.0 -

<Production Method of Examples and Comparative Examples>

(1) The oil phase components were heated (70 to 75 ° C) and mixed uniformly.

(2) The aqueous phase component was heated (70-75 ° C.) to be uniformly dissolved and mixed.

(3) To (2), the above (1) was added under stirring while maintaining a temperature (70-75 ° C) to form an emulsion, and cooled to 28-30 ° C.

Experimental Example 1-1 Moisturizing Effect of a 24-Hour Moisturizer in Hairless Mice

Acetone is applied to the back of young hairless mice 8 to 10 weeks after birth, twice a day for 5 days to impair the barrier function of the skin, and then measuring TEWL (moisture evaporation) with an evaporometer-TEWL measurement The method is described below-Examples 1, 2 and Comparative Examples 1 to 4 of Table 1 above were applied only to experimental animals having skin showing percutaneous moisture loss of 40 g / m 2 / hr or more. The average value of TEWL was measured at regular intervals, with 5 doses per group applied once daily. The result is shown in FIG. The results of the animal experiment, as shown in Figure 1, a 24-hour moisturizer I (24hr Moisturizing Complex I) mixed with honey extract, pumpkin extract and glycerin (Glycerin) and a 24-hour moisturizer II mixed with honey extract and pumpkin extract When the formulation containing (24hr Moisturizing Complex II) was applied, the change of TEWL (water evaporation amount) was significantly decreased over time compared to the formulation containing honey extract, pumpkin extract and glycerin alone. . This means that Examples 1 and 2 have a larger moisturizing effect than Comparative Examples 1-4.

<How to measure Trans Epidermal Water Loss (TEWL)>

Principle: The amount of moisture evaporated from the skin is calculated according to the area and time, and the amount of moisture evaporated is read and quantified by the temperature and moisture electronic sensors to measure the moisture of the skin.

1.Environmental conditions: Temperature and humidity are kept constant, leaving only a minimum of personnel (except the flow of air).

2. Place the TEWL probe on the subject's measurement site.

3. Do not apply excessive force to the measuring part (probe) and place it lightly (with no marks on the skin) and make an angle of 90 degrees to the ground.

4. Measure the value that the skin's TEWL value becomes constant over time. (Usually 1-3 minutes)

5. Hold the probe handle as far as possible to prevent the body temperature from being transferred.

6. Calculate the amount of water evaporated per hour per area (g / m ² / h).

[Experimental Example 1-2] Experiment of moisturizing effect of 24 hours moisturizer in human body

In the human experiment, the adult male and female 300 people who complained of dryness or dry skin were divided into six groups of 50 people each, and each of the cosmetic compositions of Examples 1 and 2 and Comparative Examples 1 to 4 of Table 1 was twice daily. It was applied to the inside of Habakku for 4 weeks. Moisturizing power was compared by measuring TEWL (moisture evaporation) under constant temperature and humidity conditions (24 ° C., relative humidity of 40%) at the time of 2 weeks and 4 weeks after the start of application and the results are shown in FIG. 2. .

As can be seen in Figure 2, the results of the human experiment is a 24-hour moisturizer I (24hr Moisturizing Complex I) and honey extract and pumpkin extract mixed with honey extract, pumpkin extract and glycerin (Glycerin) as in Figure 1 When the formulation containing the 24-hour moisturizing complex II was applied to the skin, the TEWL change (water evaporation amount) over time was significantly higher than the formulation containing the honey extract, pumpkin extract and glycerin alone. It can be seen that the shrinkage. Therefore, it can be seen that Examples 1 and 2 have a greater moisturizing effect than Comparative Examples 1 to 4.

Experimental Example 1-3 Moisturizing Sustainability Test of a 24-Hour Moisturizer

In order to determine the moisturizing persistence of the present invention, after applying Examples 1 and 2 of Table 1, the skin moisture content was measured by a coronometer (Corneometer) for 24 hours. The results are shown in FIG.

As shown in FIG. 3, a 24-hour moisturizing complex (I) mixed with a honey extract, a pumpkin extract, and glycerin (24-hr moisturizing complex I), a 24-hour moisturizing agent II (24 hr Moisturizing Complex II) mixed with a honey extract and a pumpkin extract When the containing formulation was applied to the skin once, it was found that the moisturizing power was maintained for 24 hours or more.

<How to measure a coronometer>

Principle: Moisture is measured by measuring the amount of moisture in the skin's epidermis using a sensor and numerically calculating the amount of moisture.

1. Place a probe of the corneometer on the skin area to be measured.

2. When the probe is pressed on the skin, the electrical capacitance of the skin is quantified through the sensor and displayed on the screen.

3. Repeat the measurement with different measurement sites.

4. After the measurement, wipe the sensor with a tissue such as Kimwipe and measure again.

Experimental Example 1-4 Subjective Efficacy Evaluation

At the end of the experiment, the test subjects were asked to fill out a questionnaire, and subjective efficacy evaluations of Examples 1 and 2 and Comparative Examples 1 to 4 were performed. The results are shown in Table 2 below.

Survey on Improvement of Dry Skin Applicator Respondents Very good Good usually Inadequate Example 1 24 21 5 0 Example 2 20 18 10 2 Comparative Example 1 5 10 26 9 Comparative Example 2 4 11 24 11 Comparative Example 3 6 13 25 6 Comparative Example 4 One 5 26 18

Looking at the results of Table 2, it was shown that those who applied Examples 1 and 2 feel more moisturizing effect than those who applied Comparative Examples 1 to 4, showing a significant difference in the number Able to know.

As described above, the cosmetic composition containing a 24-hour moisturizing complex (24hr Moisturizing Complex) mixed with a honey extract (Pumpkin extract) and a polyol provided by the present invention as an active ingredient It exhibits a moisturizing effect and an antioxidant effect, and in particular, in the moisturizing effect shows a much better effect than using each component separately, it is possible to provide a cosmetic composition having excellent moisturizing power which is very satisfactory to the consumer.

Claims (3)

Cosmetic composition for skin moisturizing containing a mixture of honey extract and pumpkin extract as an active ingredient. The skin moisturizing cosmetic composition according to claim 1, further comprising at least one polyol selected from the group consisting of glycerin, dipropylene glycol, propylene glycol, 1,3-butylene glycol, and polyethylene glycol. delete

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