KR101125878B1 - Cosmetic composition for moisturizing effect and enhancing elasticity on the skin - Google Patents

Abstract

The present invention relates to a skin moisturizing cosmetic composition containing a sweet nut complex (SWEET Nutritive Complex). More specifically, the cosmetic composition of the present invention contains a sweet complex consisting of horseradish extract, borage flower extract, wheat extract, sugarcane extract, and orange extract can improve skin dryness to improve skin moisturizing power. . In addition, the evening primrose extract (Oenothera Biennis Extract) is further contained in the composition to improve skin elasticity.

Evening Primrose Extract * Horseradish Extract * Wheat Extract * Sugar Cane Extract * Borage Flower Extract * Orange Extract * Skin Moisturizing * Skin Elasticity

Description

Cosmetic composition for moisturizing skin and enhancing skin elasticity {Cosmetic composition for moisturizing effect and enhancing elasticity on the skin}

1 is a graph measuring the skin moisturizing effect (animal experiment) of the cosmetic composition according to the present invention.

Figure 2 is a graph measuring the skin moisturizing effect (human body experiment) of the cosmetic composition according to the present invention.

Figure 3 is a graph of the result of measuring the skin moisture content of the cosmetic composition according to the present invention with a conniometer.

The present invention relates to a skin moisturizing cosmetic composition containing a sweet nut complex (SWEET Nutritive Complex). More specifically, the cosmetic composition of the present invention contains a sweet complex consisting of horseradish extract, borage flower extract, wheat extract, sugarcane extract, and orange extract can improve skin dryness to improve skin moisturizing power. . In addition, the evening primrose extract (Oenothera Biennis Extract) is further contained in the composition to improve skin elasticity.

The skin is divided into three layers of epidermis, dermis, and subcutaneous fat tissue in order from the outside, and protects the body from physical and chemical stimuli from the external environment. It controls the evaporation of ~ 70% of moisture out of the body. Among them, the epidermis is divided into the stratum corneum, granule layer, polar layer, and basal layer from the outside. The stratum corneum of the epidermis contains about 10-20% of moisture and exists at the outermost part of the human body to suppress evaporation of moisture from the body. Blocks excess penetration of material from outside ( J. Invest. Dermatol. 80 (Suppl.), 44-49. 1983 ). The cells constituting the stratum corneum have a high concentration of natural moisturizing factor (NMF), which is a water-soluble ingredient, which helps the skin to show flexibility and maintain proper moisture ( J. Invest. Dermatol. 54, 24-31, 1970 ). However, due to changes in the environment or changes in life patterns, various stresses and environmental pollution caused by social life, frequent face washing due to makeup habits, and natural skin aging due to age increase, moisture in the stratum corneum decreases and the skin dries. Problems related to moisturizing the skin are becoming more and more important as phenomena such as surface roughness, skin loss, and dullness appear.

As the skin ages, the decrease in elasticity progresses due to photoaging caused by ultraviolet rays, increase in age, endogenous factors such as menopause, genetic factors, and environmental factors, resulting in decreased fibroblast division, collagen synthesis, and MMP production. Due to the increase of the elasticity of the skin is reduced. In particular, around the 40s, the balance of hormones is broken, and cell regeneration ability, collagen synthesis ability, and skin lipid generation, which play an important role in skin moisturization, are greatly reduced. As consumers' desire to look young and their expectation for cosmetics are increasing, research on cosmetics aiming at improving skin elasticity reduction is being actively conducted.

In general, cosmetics are intended to clean the body, to make themselves beautiful and attractive, and to prevent aging by protecting the skin or hair from ultraviolet rays or drying. Recently, with the development of industrial society and the increase of social activities, the self-consciousness to actively express oneself is increasing, and the desire to care for and maintain the health of one's own skin using cosmetics is increasing. Accordingly, the basic and color cosmetics of various forms and formulations have been researched and developed. Among them, cosmetics having a skin moisturizing effect and skin elasticity improving cosmetics that improve skin dryness are recognized as the most important products in various categories.

Therefore, various cosmetic ingredients are being developed in the sense of improving skin moisturizing and skin elasticity. In recent years, the use of animal ingredients is rapidly used due to the declining consumer's preference for animal ingredients and the ripple of mad cow disease. Reduced and natural plant-derived materials are in the spotlight. In addition, in recent years, studies are being actively conducted to find a plant extract complex that can improve the complex skin at various angles simultaneously by using plant extracts of various efficacies rather than simply using a plant extract. In addition, consumers may find multi-functional cosmetics that are not one function, for example, plant extract complexes that can have multi-functions by increasing their preference for cosmetics that have moisturizing as a base and elasticity as an additional function. Developing has become a very urgent and important matter.

Therefore, the present inventors have studied to develop a plant extract complex that can solve the problem of skin moisturizing and elasticity at the same time with the above-mentioned purpose, the extract of oleander tree, borage flower extract, wheat extract, sugarcane extract, orange It has been found that when the cosmetic composition is prepared using the SWEET Nutritive Complex composed of extracts, an excellent skin moisturizing effect can be obtained. In addition, it was found that by further containing the Evening Primrose extract in the composition can exhibit a skin moisturizing effect and at the same time excellent skin elasticity improvement, and completed the present invention.

Accordingly, it is an object of the present invention to provide a cosmetic composition for moisturizing skin containing a oleracea extract, a borage flower extract, a wheat extract, a sugarcane extract, and an orange extract.

In addition, another object of the present invention is to provide a cosmetic composition having an excellent skin elasticity enhancing effect by further containing an evening primrose extract in the composition.

In order to achieve the above object, the skin moisturizing cosmetic composition according to the present invention is a sweet complex (SWEET Nutritive Complex) consisting of horseradish extract, borage flower extract, wheat extract, sugarcane extract, and orange extract as an active ingredient It is characterized by containing. In addition, the composition is characterized in that it further contains an evening primrose extract.

Manufacturers of plant extract raw materials used in the present invention are as follows.

-Evening Primrose Extract: Soliance (France)

Horsetail Extract: Efal Bio. (Israel)

-Borage Flower Extract: Doosan (Korea)

Wheat Extract: Pentapharm (Switzerland)

Sugarcane Extract: Ajimoto (Japan)

-Orange Extract: Colletica (France)

Hereinafter, the present invention will be described in more detail.

The sweet complex is composed of oleracea extract, borage flower extract, wheat extract, sugarcane extract and orange extract, each contained 0.01 to 20% by weight based on the total weight of the composition. In addition, each extract is preferably mixed in a mixing ratio of 1: 1: 1: 1: 1. However, the usable range of each plant extract is not limited to the above ratios, and each extract may be combined at an appropriate ratio.

Botanic extract is a natural oil rich in vitamins A, C, and E, which have excellent skin beauty effects such as antioxidant and wrinkle improvement.Boraji flower extract contains more than 20% of linolenic acid, a representative essential fatty acid, to strengthen skin barrier and cuticle Suppresses moisture loss through In addition, the wheat extract contains a large amount of carbohydrates, which have excellent moisture retention ability, that is, hygroscopicity, has excellent moisturizing properties in a dry environment, and the sugarcane extract contains a large amount of amino acids which are raw materials for skin protein components such as collagen and elastin. It will act as a supplement to skin protein. In addition, the orange extract contains flavonoids, a key component of blood circulation in skin cells, to help improve blood flow in the skin.

SWEET Nutritive Complex according to the present invention is a plant extract combination based on scientific basic data on skin and moisturizes the skin when using a mixture of barley tree extract, borage flower extract, wheat extract, sugarcane extract, and orange extract There is a synergistic effect, and even if used together with Evening Primrose extract can enhance the efficacy in terms of skin elasticity.

Evening primrose extract used in the present invention is a component extracted from the mysterious evening primrose, which blooms only at night, and has high content of polyphenols, organic acids, amino acids, and the like, and collagen IV and VII constituting the epidermal-dermal junction (DEJ). It is known to promote skin synthesis and to enhance skin elasticity. In addition, it inhibits the activity of the MMP-9 enzyme that degrades collagen, preventing the decay of DEJ due to sunburn, aging and external stress.

In the cosmetic composition according to the present invention, the SWEET Nutritive Complex contains 0.01 to 30.0% by weight, preferably 0.1 to 10.0% by weight, based on the total weight of the composition. In addition, evening primrose extract is contained in a concentration of 0.01 to 30.0% by weight, preferably 0.1 to 10.0% by weight based on the total weight of the composition in O / W formulation. It is not possible to expect the desired effect at each less than 0.01% by weight, and when it exceeds 30.0% by weight, there is a fear of cosmetic degeneration, it is not easy to control the viscosity of the cosmetic formulation, and it is easy to develop as a cosmetic formulation due to the occurrence of phase change during the preparation of the emulsion formulation. It will be difficult and economical for production.

The cosmetic composition according to the present invention can be used for skin elasticity strengthening, skin moisturizing cosmetics, and the formulation is not particularly limited, and for example, soft cosmetics, nourishing cosmetics, massage creams, nourishing creams, packs, gels or skin adhesives. It may be a formulation of a type cosmetic, or a transdermal formulation.

Hereinafter, the present invention will be described in more detail with reference to Examples and Test Examples, but the scope of the present invention is not necessarily limited to these examples.

Examples 1-2 and Comparative Examples 1-7

In order to investigate the moisturizing effect of SWEET Nutritive Complex, we prepared sweet complexes with a ratio of 1: 1: 1: 1: 1 in extracts of botanic extract, purple flower extract, wheat extract, sugarcane extract and orange extract. To prepare a cosmetic composition of Examples 1 to 2 and Comparative Examples 1 to 7 by the composition of Table 1. In the following Examples 1 and Comparative Examples 1 and 3 to 7 are O / W formulations, and Example 2 and Comparative Example 2 have a gel formulation.

division Raw material name (content: wt%) Example Comparative example One 2 One 2 3 4 5 6 7 Paid
ingredient Stearic acid 1.0 - 1.0 - 1.0 1.0 1.0 1.0 1.0 Cetearyl Alcohol 0.2 - 0.2 - 0.2 0.2 0.2 0.2 0.2 Hydrogenated Oil 0.7 - 0.7 - 0.7 0.7 0.7 0.7 0.7 Lipophilic glyceryl stearate 0.5 - 0.5 - 0.5 0.5 0.5 0.5 0.5 Hydroxanthetidressitine / C12-16 Alcohol / Palmetic acid 1.0 - 1.0 - 1.0 1.0 1.0 1.0 1.0 antiseptic 0.3 - 0.3 - 0.3 0.3 0.3 0.3 0.3 Polydecene 4.0 - 4.0 - 4.0 4.0 4.0 4.0 4.0 Meadowfoam seed oil 1.0 - 1.0 - 1.0 1.0 1.0 1.0 1.0 Pentaerythritol tetraisostearate 3.0 - 3.0 - 3.0 3.0 3.0 3.0 3.0 Dimethicone 0.5 - 0.5 - 0.5 0.5 0.5 0.5 0.5 Cetyloctanoate 2.0 - 2.0 - 2.0 2.0 2.0 2.0 2.0 Decyl cocoate 1.0 - 1.0 - 1.0 1.0 1.0 1.0 1.0 Cyclomethicone 3.0 - 3.0 - 3.0 3.0 3.0 3.0 3.0 Tocopheryl acetate 0.1 - 0.1 - 0.1 0.1 0.1 0.1 0.1 Awards
Ingredient 1 Purified water To 100 To 100 To 100 To 100 To 100 To 100 To 100 To 100 To 100 glycerin 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 Butylene glycol 5.0 3.0 5.0 3.0 5.0 5.0 5.0 5.0 5.0 Disodium ID 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 0.02 Tee 0.15 - 0.15 - 0.15 0.15 0.15 0.15 0.15 antiseptic 0.2 - 0.2 - 0.2 0.2 0.2 0.2 0.2 Trehalose - 1.0 - 1.0 - - - - - Hyaluronic acid - 2.0 - 2.0 - - - - - Fiji-75 - 1.0 - 1.0 - - - - - Potassium hydroxide - 0.08 - 0.08 - - - - - Sweet Complex (Westwood Extract: Purple Flower Extract: Wheat Extract: Sugarcane Extract: Orange Extract = 1: 1: 1: 1: 1) 5.0 5.0 - - - - - - - Horseradish extract - - - - 5.0 - - - - Bora Flower Extract - - - - - 5.0 - - - Wheat extract - - - - - - 5.0 - - Sugarcane Extract - - - - - - - 5.0 - Orange extract - - - - - - - - 5.0 Awards
Component 2 Carbomer 1% aqueous solution 12.0 20.0 12.0 20.0 12.0 12.0 12.0 12.0 12.0 Xanthan Gum - 0.1 - 0.1 - - - - - Alcohol ingredients Ethanol 95% - 5.0 - 5.0 - - - - - Polyoxyethylene Hydrogenated Castor Oil - 0.3 - 0.3 - - - - - antiseptic - 0.3 - 0.3 - - - - - incense - Quantity - Quantity - - - - -

<< The manufacturing method of Example 1 and Comparative Examples 1 and 3-7 >>

(1) The oil phase components were heated (70 to 75 ° C) and mixed uniformly.

(2) The aqueous phase component 1 was heated (70 to 75 ° C.) to be uniformly dissolved and mixed.

(3) To (2), while stirring (1) above while keeping the temperature (70 ~ 75 ℃) to make an emulsion, the aqueous phase component 2 was continuously added and then cooled to 28-30 ℃.

<< manufacturing method of Example 2 and Comparative Example 2 >>

(1) The water phase component 1 was mixed uniformly.

(2) The alcohol components were mixed uniformly.

(3) The aqueous phase component 2 was slowly added to (1) under stirring, and then gradually increased, and then the alcohol component was continuously added to prepare a gel formulation.

Test Example 1 : Experiment of moisturizing effect of SWEET Nutritive Complex

 The skin moisturizing improvement effect of the cosmetic composition prepared by the composition of Examples 1 to 2 and Comparative Examples 1 to 7 was measured by the following method for the animal and the human body.

<< Animal Testing >>

8-10 weeks after birth, acetone is applied to the back of young hairless mice periodically twice a day for 5 days, impairing the barrier function of the skin such as experimental animals, and measuring TEWL with the evaporimeter to measure 40g / For the experimental animals with skin showing transdermal moisture loss of ㎡ / hr or more, the compositions of Examples 1 and 2 and Comparative Examples 1 to 7 were continuously administered twice a day for 3 days at a dose of 200 μl per 5 cm ² of skin area. TEWL was measured at regular intervals during application. The results are shown in Figure 1 below.

[Measurement of Trans Epidermal Water Loss (TEWL)]

Principle: The amount of moisture evaporated from the skin is calculated according to the area and time, and the amount of moisture evaporated is read by the temperature and moisture electronic sensors, and the numerical value is measured to measure the moisture of the skin.

1.Environmental conditions: Temperature and humidity are kept constant, leaving only a minimum of personnel (as far as possible).

2. Place the TEWL probe on the measurement site of the subject.

3. Do not apply excessive force to the measuring part and place it lightly (with no marks on the skin) and make an angle of 90 degrees to the ground.

4.Measure the TEWL level of skin becomes constant over time. (Usually 1-3 minutes)

5. Hold the handle of the probe as far as possible to prevent the body temperature from being transmitted.

6.Calculate the amount of water evaporated per hour per area (g / m 2 / hr).

As can be seen in Figure 1, it contains a SWEET Nutritive Complex, which is a mixture of the barley extract, borage flower extract, wheat extract, sugarcane extract, orange extract 1: 1: 1: 1: 1 In Examples 1 to 2, it was found that the change value (water evaporation amount) of TEWL decreased over time. In Comparative Examples 3 to 7 each containing one extract, although the moisturizing effect was increased compared to Comparative Example 1, the moisturizing effect was relatively insignificant compared to Example 1 using the sweet complex. This means that Examples 1 to 2 containing the sweet composite according to the present invention have a larger moisturizing effect than Comparative Examples 1 to 7.

<< Human Body Test >>

Fifteen adult men and women who complained of dryness or dry skin were applied to the face twice daily for four weeks with the cosmetic compositions of Examples 1-2 and Comparative Examples 1-7. At the time of 1 week, 2 weeks, and 4 weeks after the start of application and at the time of application, TEWL was measured under constant temperature and constant humidity (24 ° C., 40% relative humidity) to compare moisturizing power, and the results are shown in FIG. 2. . In addition, the skin moisture content was measured by a Koniometer and the results are shown in FIG. 3.

Separately, at the end of the test, the subjects were asked to fill out a questionnaire, which was evaluated mechanically and subjectively. The results are shown in Table 2 below.

[Method of measuring corneometer]

Principle: Moisture is measured by measuring the amount of moisture in the skin's epidermis using a sensor and quantifying it to calculate the amount of moisture.

1.Place the probe of the Koniometer on the skin area to be measured.

2. Press the probe on the skin and the sensor will quantify the skin's electrical conductivity and display it on the screen.

3. Repeat the measurement with different measuring area.

4.After the measurement, wipe the sensor with a tissue such as Kimwipe and measure.

Survey on Improvement of Dry Skin Applicator Respondents Very good Good usually Inadequate Example 1 7 5 3 0 Example 2 4 5 6 0 Comparative Example 1 0 2 8 5 Comparative Example 2 0 2 9 4

As can be seen in Figure 2, as shown in Figure 1, it contains a honeycomb extract, borage flower extract, wheat extract, sugarcane extract, orange extract in a 1: 1: 1: 1: 1 mixture It can be seen that Examples 1 to 2 show a tendency that the change value (water evaporation amount) of TEWL decreases over time, and Examples 1 to 2 according to the present invention are compared with Comparative Examples 1 to 7 This means that the moisturizing effect is relatively higher.

In addition, the content of the sweet complex in Example 1 and Example 2 is the same, but the effect was found to be smaller in Example 2, which is believed to be due to the difference in formulation, the emulsion formulation is generally more moisturizing than the gel formulation Because it is larger.

In addition, it was confirmed through Example 3 that Examples 1 to 2 showed a greater increase in moisture content over time than in Comparative Examples 1 to 7, which indicates that the moisturizing effect is greater.

In addition, looking at the results of Table 2, it can be seen that the results of the investigation that people who applied Examples 1 and 2 felt that there was a relatively more moisturizing effect than those who applied Comparative Examples 1-2.

Test Example 2 : Collagen Synthesis Promoting Effect of Evening Primrose Extract

Human fibroblasts were cultured in a 24-well plate incubator, and then replaced with a medium containing evening primrose extract (Oenotherol; manufacturer: Soliance) at concentrations of 0, 1, 5, and 10 ppm, respectively. On the third day of culture, 0.5 ml of DMEM medium containing 10% fetal calf serum was added to each well, followed by 10 μCi of L [2,3,4,5- ³ H] -proline. After 24 hours, the media and cells in each well are scraped and washed in 5% Trichloroacetic acid (TCA) solution, and then dispensed into two test tubes and one type I cola in one test tube. 1 unit / μl of genase (type I collagenase) was added and incubated at 37 ° C. for 90 minutes, and other test tubes were stored at 4 ° C. Thereafter, 0.05 ml of 50% trichloroacetic acid was added to all test tubes, and the mixture was left at 4 ° C. for 20 minutes, followed by centrifugation at 12,000 rpm for 10 minutes, respectively. ) To obtain CPM (CPM; Count Per Minute) value, and measured collagen biosynthesis value (RCB; Relative Collagen Biosynthesis) for the control group and the experimental group based on Equation 1 below, and the results are shown in Table 3 below.

Evening Primrose Extract Concentration (ppm) Collagen Biosynthesis Ratio (RCB) (%) 10 140 5 122 One 112 0 (control) 100

As can be seen in Table 3, the evening primrose extract was found to increase the concentration of collagen biosynthesis of fibroblasts.

[Example 3 and Comparative Examples 8-9]

To the lotion of Example 3 and Comparative Examples 8 to 9 was prepared in the composition of Table 4.

Ingredients (content: wt%) Example 3 Comparative Example 8 Comparative Example 9 Purified water To 100 To 100 To 100 Evening Primrose Extract 3.0 - 6.0 Sweet Complex 3.0 - - Vegetable hydrogenated oil 1.5 1.5 1.5 Stearic acid 0.60 0.60 0.60 Glyceryl Stearate 1.00 1.00 1.00 Cetearyl Alcohol 2.00 2.00 2.00 Polyglyceryl-10 pentastearate & behenyl alcohol & sodium stearoyl lactylate 1.00 1.00 1.00 Arakidilbehenyl Alcohol & Arakidil Glucoside 1.00 1.00 1.00 Cetearyl Alcohol & Cetearyl Glucoside 2.00 2.00 2.00 PEG-100 Stearate & Glycerololate & Propylene Glycol 1.50 1.50 1.50 Caprylic / Capric Triglycerides 11.00 11.00 11.00 Cyclomethicone 6.00 6.00 6.00 Preservative, incense Quantity Quantity Quantity Triethanolamine 0.10 0.10 0.10

Test Example 3 Measurement of Skin Elasticity Improvement in Human Body

The skin elasticity improvement effect of the lotion of Example 3 and Comparative Examples 8 to 9 prepared as shown in Table 4 was measured. After dividing 20 healthy women over 30 years old at a temperature of 24-26 ° C and a humidity of 75% into two sets, each group of the skin lotion of Example 3 and Comparative Examples 8-9 was applied to the face twice a day for 12 weeks and then skin Skin elasticity was measured using an elasticity measuring instrument (Cutometer SEM 575, C + K Electronic Co., Germany). The results are shown in Table 5 below, and the results in Table 5 are described as R8 (R8 (left) -R8 (right)) values of Cutometer SEM 575, where R8 values indicate the nature of skin viscoelasticity. In addition, at the end of the test, the test subjects were asked to fill out a questionnaire, and the subjective efficacy evaluation was conducted at the same time as the mechanical evaluation. The results are shown in Table 6 below.

Skin elasticity Experimental product Skin elasticity effect Example 3 0.72 Comparative Example 8 0.11 Comparative Example 9 0.34

As shown in Table 5, in the group coated with the material of Example 3 containing both Evening Primrose extract and the sweet complex, it was confirmed that the skin elasticity was further increased as compared with the group coated with Comparative Example 8. In particular, it was confirmed that the skin elasticity is further increased in the group to which the material of Example 3 containing both the Evening Primrose extract and the sweet complex is applied than the group to which the Evening Primrose extract is contained only Comparative Example 9.

Skin Elasticity Improvement Survey Results Applicator Number of respondents Very good Good usually Inadequate Example 3 7 3 0 0 Comparative Example 8 One 3 3 3 Comparative Example 9 3 4 2 One

Through the results of the survey of Table 6, it was confirmed that the skin elasticity was further improved when Example 3 containing both Evening Primrose extract and the sweet complex was applied.

As described above, the skin moisturizing cosmetic composition of the present invention contains a sweet complex (SWEET Nutritive Complex), which is a mixture of five kinds of barley tree extract, borage flower extract, wheat extract, sugarcane extract, and orange extract It has a moisturizing effect on the skin, and also contains an Evening Primrose extract to increase the synthesis of collagen in the dermal layer can provide a cosmetic composition excellent in skin elasticity enhancing effect.

Claims (5)

Cosmetic composition for moisturizing skin, comprising a mixed extract consisting of horseradish extract, borage flower extract, wheat extract, sugarcane extract, and orange extract as an active ingredient. The cosmetic composition according to claim 1, further comprising evening primrose extract. The cosmetic composition according to claim 2, wherein the composition is for enhancing skin elasticity to improve skin elasticity through an increase in collagen of the dermal layer. The cosmetic composition according to claim 1, wherein the mixed extract is contained in an amount of 0.01 to 30% by weight based on the total weight of the composition. The cosmetic composition according to claim 2, wherein the evening primrose extract is contained in an amount of 0.01 to 30% by weight based on the total weight of the composition.

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