KR100787312B1 - Cosmetic composition for moisturizing effect on the skin containing the mixture of jasmine extract, arnica extract and yarrow extract - Google Patents

Abstract

The present invention relates to a moisturizing cosmetic composition, characterized in that the moisturizing cosmetic composition according to the present invention contains from 0.01 to 60% by weight of jasmine extract, arnica extract and yarrow extract based on the total weight of the cosmetic composition.

Moisturizing cosmetic composition according to the present invention, by giving a moisturizing effect to the skin using an extract of a mixture of three kinds of jasmine extract, arnica extract and yarrow extract, lifestyle factors such as excessive washing or bathing, dry air, pollution Due to environmental factors such as substances and endogenous diseases such as atopic skin or aged skin, the skin having a reduced function as a barrier can be moisturized to protect the skin. In addition, it is possible to maximize the moisturizing effect of the extract by setting the optimum mixing ratio of jasmine extract, arnica extract and yarrow extract. Meanwhile, the moisturizing cosmetic composition according to the present invention has an effect that can be applied to various formulations, such as an oil-in-water emulsion formulation and a gel formulation.

Jasmine, Arnica, Yarrow, Moisturizing

Description

Cosmetic composition for moisturizing effect on the skin containing the mixture of jasmine extract, arnica extract and yarrow extract}

1 is a graph showing the change of TEWL (Trans Epidermal Water Loss) when each extract or a mixture of extracts is applied to the skin after acetone prolonged treatment.

Fig. 2 is a graph showing a change in TEWL when the moisturizing cosmetic composition according to the present invention is applied to mouse skin after acetone long-term treatment.

3 is a graph showing the change in TEWL when the moisturizing cosmetic composition according to the present invention is applied to human skin after acetone long-term treatment.

Fig. 4 is a graph showing the results of the Koniometer measurement when the moisturizing cosmetic composition according to the present invention is applied to human skin after acetone long-term treatment.

The present invention relates to a moisturizing cosmetic composition, comprising an extract of a mixture of jasmine extract, arnica extract, yarrow extract to provide a moisturizing cosmetic composition for moisturizing effect on the skin.                         

The most important function of the outermost epidermis of the skin is to protect the skin from physical and chemical irritants such as various stimuli from the outside, such as chemicals, air pollutants, dry environment, ultraviolet rays, etc. It is a protective function that prevents excessive divergence of moisture through the body, and this protective function can be maintained only when the stratum corneum composed of keratinocytes is normally formed. According to J. Invest. Dermatol . 1983; 80: 44-49, the outermost stratum corneum (horney layer) is formed from keratinocytes and surrounds keratinocytes with differentiation. It is composed of a geological layer. Keratinocytes are characteristic cells whose basal cells, which continuously proliferate in the epidermal layer, undergo morphological and functional changes in stages and rise to the surface of the skin. Exfoliated and new keratinocytes take over their function. This repetitive process of change is called "epidermal differentiation" or "keratinization." During keratinization, keratinocytes form the stratum corneum by generating natural moisturizing factor (NMF) and intercellular fat (ceramide, cholesterol, fatty acids), making the stratum corneum firm and flexible. It has a function as).

However, these stratum corneum can easily lose its function due to excessive face washing, lifestyle factors such as bathing, environmental factors such as dry air and pollutants, and endogenous diseases such as atopic or aged skin. In recent years, more and more people are complaining about dry skin symptoms and related disorders. Therefore, many studies have been conducted to supply moisture from the outside or to prevent water loss from the body in order to maintain proper skin moisture, and in fact, various types of moisturizers having moisture retention capabilities have been developed and mainly cosmetics. It is widely used in the field.

Looking at the external environment in recent years, the use of animal raw materials that can cause mad cow disease due to ripples such as mad cow disease has been banned, and the use of animal raw materials is not preferred, and customers' preference for vegetable raw materials has increased relatively. According to this trend, moisturizers have also been obtained from vegetable raw materials, and in particular, it is necessary to use raw materials extracted from flowers, which are easy to highlight to consumers.

The present invention is to solve the above problems, an object of the present invention, by using the extract of the mixture of jasmine extract, arnica extract and yarrow extract to give a moisturizing effect on the skin, such as excessive washing or bathing life It protects the skin by moisturizing the skin with reduced function as a barrier due to habitual factors, environmental factors such as dry air, pollutants, and endogenous diseases such as atopic or aged skin. In addition, it aims to maximize the moisturizing effect of the extract by setting the optimum mixing ratio of jasmine extract, arnica extract and yarrow extract. On the other hand, it is another object of the present invention to apply to a variety of formulations, such as formulation of oil-in-water emulsion, formulation of gel.

In order to achieve the above object, the moisturizing cosmetic composition according to the present invention is characterized in that it contains jasmine extract, arnica extract and yarrow extract 0.01 to 60% by weight relative to the total weight of the cosmetic composition.

In the moisturizing cosmetic composition according to the present invention, the weight ratio of the jasmine extract, arnica extract and yarrow extract is characterized in that the 5.5 ~ 6.5: 1.75 ~ 2.25: 1.75 ~ 2.25.

In the moisturizing cosmetic composition according to the present invention, the weight ratio of the jasmine extract, arnica extract and yarrow extract is characterized in that 6: 2: 2.

Hereinafter, the moisturizing cosmetic composition according to the present invention will be described in more detail.

The inventors of the present invention, among the various extracts extracted from flowers used in cosmetics, examine the raw materials having a moisturizing effect, which are easy to highlight the image to consumers, and finally select three kinds of jasmine, arnica, and yarrow on the skin. A moisturizing cosmetic composition having a moisturizing effect was completed.

Furthermore, as a result of extensive research of the present invention, the mixture of jasmine, arnica and yarrow can be set in various ratios, but considering the moisturizing effect of the entire mixture, the total weight of the extract (20% butylene glycol base) Jasmine: Arnica: Yarrow was set to 6: 2: 2 to find a moisturizing effect in raw materials and cosmetic compositions and completed the present invention.

The mixture of the extract in the moisturizing cosmetic composition of the present invention contains 0.01 to 60.0% by weight, preferably 2.0 to 20.0% of the total weight of the composition with respect to the oil-in-water emulsion formulation, solubilizing gel formulation.

The term "jasmine" referred to in the specification of the present invention is commonly used to generically belong to plants belonging to Jasminum sp . It is an evergreen shrub and has about 200 species in the tropics and subtropics. It is native to the Himalayas and has white and yellow flowers.

"Arnica" also has the scientific name Arnica montana , which belongs to the perennial plant of the Asteraceae. It grows in highland grasses and is 20 to 30 cm in height. Flowers bloom in yellow in June and July, and mainly use flowers and rhizomes.

In addition, "Yarrow" is a scientific name Achillea millefolium belongs to the perennial herb of the Asteraceae family. It is native to Europe, grows from 30 to 60 cm, and blooms white, yellow, and red flowers from June and July.

Extracts contained in the moisturizing cosmetic composition according to the present invention are prepared according to the following method.

Preparation of Extract

1. Preparation of Jasmine Extract

When the jasmine petal is 100 parts by weight, 20 parts by weight of 1,3-butylene glycol and 80 parts by weight of purified water were mixed to prepare an extraction solvent, and the jasmine petals were extracted from the extraction solvent at 40-45 ° C. for 16 hours. After extraction, it was filtered and then decolorized with PVP (Kollidon) and a preservative was added. Store at 0-5 ° C. for at least 1 week after preparation. And for more precise filtration, the filtration was made by cross flow filtering with a 10 micrometer diameter and completely transparent.

It was also sterilized at 121 ° C. for 60-90 seconds and packaged as raw material.

2. Preparation of Arnica Extract

 When Arnica petals were 100 parts by weight, 20 parts by weight of 1,3-butylene glycol and 80 parts by weight of purified water were mixed to prepare an extraction solvent, and Arnica petals were extracted at 40-45 ° C. for 16 hours. After extraction, the resultant was filtered and then decolorized with PVP (Kollidon) and a preservative was added. Store at 0-5 ° C. for at least 1 week after preparation. And for more precise filtration, the filtration was made by cross flow filtering with a 10 micrometer diameter and completely transparent.

It was also sterilized at 121 ° C. for 60-90 seconds and packaged as raw material.

3. Preparation of Yarrow Extract

When the yarrow petals were 100 parts by weight, 20 parts by weight of 1,3-butylene glycol and 80 parts by weight of purified water were mixed to prepare an extraction solvent, and the yarrow petals were extracted at 40-45 ° C. for 16 hours. After extraction, the resultant was filtered and then decolorized with PVP (Kollidon) and a preservative was added. Store at 0-5 ° C. for at least 1 week after preparation. And for more precise filtration, the filtration was made by cross flow filtering with a 10 micrometer diameter and completely transparent.

It was also sterilized at 121 ° C. for 60-90 seconds and packaged as raw material.

4. Preparation of Mixed Extract of Jasmine, Arnica and Yarrow

As an alternative to the preparation of the extracts of jasmine, arnica and yarrow as described above, there is a method of mixing the jasmine petals, the arnica petals and the yarrow petals and then extracting the petal mixture. Jasmine petals: Arnica extract: Yarrow petals are mixed at a weight ratio of 6: 2: 2, and when the petal mixture is 100 parts by weight, 20 parts by weight of 1,3-butylene glycol and 80 parts by weight of purified water are prepared to prepare an extraction solvent. The petal mixture was extracted 16 h at 40-45 ° C. After extraction, the resultant was filtered and then decolorized with PVP (Kollidon) and a preservative was added. Store at 0-5 ° C. for at least 1 week after preparation. And for more precise filtration, the filtration was made by cross flow filtering with a 10 micrometer diameter and completely transparent.

It was also sterilized at 121 ° C. for 60-90 seconds and packaged as raw material.

In addition, the conditions of the experiment for demonstrating the effect of the present invention are as follows.

Trans Epidermal Water Loss (TEWL) was used as a criterion for measuring the moisturizing effect of the moisturizing cosmetic composition according to the present invention and the plant extract contained in the composition. TEWL represents the amount of water evaporated from the surface of the skin. The smaller the amount, the better the moisture retention. TEWL was measured according to the following method.

How to measure Trans Epidermal Water Loss (TEWL)

1. Principle: The amount of moisture evaporated from the skin is calculated according to the area and time, and the amount of moisture evaporated is read and quantified by the temperature and moisture electronic sensors to measure the moisture of the skin.

2. Environmental conditions: Ensure that the temperature and humidity are kept constant, leaving only a minimum of personnel (preferably to block the flow of air) other than the measurement and the subject.

3. Measuring process

(1) Place the TEWL probe on the measurement site of the subject.

(2) Do not apply excessive force to the measuring part, that is, put it lightly so that no marks remain on the skin and make an angle of 90 degrees with the ground.

(3) Measure the value that the TEWL value of skin becomes constant as time passes (usually 1-3 minutes).

(4) Hold the probe handle as far as possible to prevent the body temperature from being transmitted.                     

(5) Calculate the amount of water evaporated per hour per area (g / m ² / h).

Another method of measuring the skin's moisturizing power is to use a coronometer. The specific method is as follows.

How to measure a coronometer

1. Principle: Moisture is measured by measuring the amount of moisture in the skin's epidermis using a sensor and numerically calculating the amount of moisture.

2. Measuring process

(1) Put the probe of the Koniometer on the skin area to be measured.

(2) When the probe is pressed on the skin, the electrical conductivity of the skin is quantified through the sensor and displayed on the screen.

(3) Repeat the measurement with different measuring parts.

(4) After measuring once, wipe the sensor with a tissue such as Kimwipe and measure it.

TEWL was measured according to the above-described procedure in order to demonstrate the moisturizing effect of the jasmine extract, the arnica extract and the yarrow extract prepared by the above extraction method.

Experimental Example 1: Moisturizing Effect of Mixed Extracts

In order to compare the difference in moisturizing effects of applying jasmine extract, arnica extract and yarrow extract to the skin alone and applying the mixture obtained by mixing the extracts to the skin, first applying only jasmine extract (# 1) The moisturizing effect was measured for the case where only Arnica extract was applied (# 2) and the case where only Yarrow extract was applied (# 3). In addition, the weight ratio of jasmine extract: Arnica extract: Yarrow extract was measured for the moisturizing effect of the mixture (# 4 ~ # 8) of the extract as shown in Table 1 below. The weight ratio of the three extracts used in the experiment is shown in Table 1 below.

Experimental Example Jasmine arnica Yarrow #One 10 0 0 #2 0 10 0 # 3 0 0 10 #4 8 One One # 5 7 1.5 1.5 # 6 6 2 2 # 7 5 2.5 2.5 #8 4 3 3

Experiments for measuring the moisturizing effect of the extracts of the # 1 to # 8. 8-10 weeks after birth, acetone is applied to the back of young hairless mice twice a day for 5 days in order to impair the barrier function of the back skin and then measure TEWL (Transepidermal Water Loss) with the evaporimeter. Vehicles (butylene glycol 20% aqueous solution) and extracts of Table 1 above were used only twice a day at a dose of 200 μl per 5 cm ² of skin area for experimental animals with skin showing more than 40 g / ㎡ / hr transdermal moisture loss. TEWL was measured at regular intervals with continuous application for 3 days. Trans Epidermal Water Loss (TEWL) refers to the amount of water evaporated from the skin surface. The results are shown in FIG.

As shown in Figure 1, it can be seen that the use of Jasmine extract, Arnica extract, Yarrow extract by using a mixture than the value of TEWL is lower. Among them, it was found that the moisturizing effect was most excellent when the weight ratio of jasmine extract, arnica extract, and yarrow extract was 6: 2: 2 (# 6).

Hereinafter, the moisturizing cosmetic composition according to the present invention will be described in detail with reference to Examples, but the present invention is not limited only to these Examples.

Example

Jasmine extract, Arnica extract, and Yarrow extract prepared above were mixed in a weight ratio of 6: 2: 2 to an oil-in-water emulsion, a solubilizing gel-type cosmetic. The addition amount was 2.0 weight% (Example 1) and 10.0 weight% (Example 2) with respect to the whole composition, respectively. Comparative Example 1 same as the composition of Example 1, except that the extraction mixture was not added to demonstrate the moisturizing effect of the extraction mixture, except that the composition of Example 2 was not added Comparative experiments were also conducted with respect to the moisturizing effect of Comparative Example 2. Specific compositions of Examples 1 to 2 and Comparative Examples 1 to 2 are as shown in Table 2 below. The following formulations are O / W formulations or gel formulations, in weight percent.

division Raw material name Example 1 Example 2 Comparative Example 1 Comparative Example 2 Oil phase Stearic acid 1.0 - 1.0 - Cetearyl Alcohol 0.2 - 0.2 - Hydrogenated Oil 0.7 - 0.7 - Lipophilic glyceryl stearate 0.5 - 0.5 - Hydrogenated Lecithin / C12-16 Alcohol / Palmetic Acid 1.0 - 1.0 - antiseptic 0.3 - 0.3 - Polydecene 4.0 - 4.0 - Meadowfoam seed oil 1.0 - 1.0 - Pentaerythritol tetraisostearate 3.0 - 3.0 - Dimethicone 0.5 - 0.5 - Cetyloctanoate 2.0 - 2.0 - Decyl cocoate 1.0 - 1.0 - Cyclomethicone 3.0 - 3.0 - Tocopheryl Acetate 0.1 - 0.1 - Water component 1 Purified water To 100 To 100 To 100 To 100 glycerin 4.0 4.0 4.0 4.0 Butylene glycol 5.0 3.0 5.0 3.0 Disodium ID 0.02 0.02 0.02 0.02 Tee 0.15 - 0.15 - antiseptic 0.2 - 0.2 - Trehalose - 1.0 - 1.0 Hyaluronic acid - 2.0 - 2.0 Fiji-75 - 1.0 - 1.0 Potassium hydroxide - 0.08 - 0.08 Fleur Hydra Complex (Jasmine: Arnica: Yarrow = 6: 2: 2) 2.0 10.0 - - Water component 2 Carbomer 1% solution xanthan gum 12.0- 20.0 0.1 12.0- 20.0 0.1 Alcohol ingredients Ethanol 95% - 5.0 - 5.0 Polyoxyethylene Hydrogenated Castor Oil - 0.3 - 0.3 antiseptic - 0.3 - 0.3 incense - Quantity - Quantity

Each cosmetic composition according to Examples 1 to 2 and Comparative Examples 1 to 2 was prepared by the following method.

Example 1 and Comparative Example 1 (in-water emulsion formulation)

(1) The oil phase components were heated (70 to 75 ° C) and mixed uniformly.

(2) The aqueous phase component 1 was heated (70 to 75 ° C.) to be uniformly dissolved and mixed.

(3) In (2), (1) was added under stirring while maintaining a temperature (70-75 ° C) to form an emulsion, and water phase component 2 was continuously added, followed by cooling to 28-30 ° C.

Example 2 and Comparative Example 2 (solubilizing gel formulation) method of preparation

(1) The aqueous phase component 1 was mixed uniformly.

(2) The alcohol components were mixed uniformly.

(3) The aqueous phase component 2 was slowly added to (1) under stirring, and then gradually increased, and then the alcohol component was continuously added to obtain a gel formulation.

Experimental Example 2 Measurement of Skin Moisturizing Improvement Effect of Cosmetic Compositions According to Examples 1 and 2 and Comparative Examples 1 and 2

 1. Animal Experiment

8-10 weeks after birth, acetone is applied to the back of the young hairless mice periodically twice a day for 5 days to impair the barrier function of the skin of the back, and the TEWL is measured by the evaporimeter to measure 40 g / ㎡ / For each experimental animal with skin showing transdermal moisture loss of hr or more, each composition according to Examples 1 to 2 and Comparative Examples 1 to 2 was continuously applied twice a day for 3 days at a dose of 200 μl per 5 cm ² of skin area. TEWL was measured at regular intervals. The results are shown in FIG.

As shown in Fig. 2, the composition containing the extract of Jasmine extract, Arnica extract and Yarrow extract in a weight ratio of 6: 2: 2 (Examples 1 and 2) does not contain the mixed extract ( Compared with Comparative Example 1 and Comparative Example 2), it can be seen that the change value (water evaporation amount) of TEWL over time is smaller. This indicates that each of Examples 1 and 2 has a greater moisturizing effect than Comparative Examples 1 and 2.

2. Human body experiment

In addition to the animal experiments, human experiments were also performed. 15 adult men and women who complain of dryness or dry skin are divided into two sets, and the cosmetic compositions of Comparative Examples 1 and 1 and the cosmetic compositions of Comparative Examples 2 and 2 are twice daily for 4 weeks in each group. Was applied. At the time of 1 week, 2 weeks, and 4 weeks after the start of application and at the time of application, TEWL was measured by the method described above at constant temperature and constant humidity (24 ° C, relative humidity of 40%). 3 is shown. In addition, the skin moisture content was measured using a conniometer in the same manner as described above, the results are shown in FIG. Separately, at the end of the test, subjects were asked to answer the questionnaire, and mechanical evaluation and subjective efficacy evaluation were also performed. The results are shown in Table 3.

(1) TEWL measurement result

Referring to FIG. 3, the change value of TEWL (moisture evaporation amount) over time when a formulation containing an extract containing a mixture of jasmine extract, arnica extract, and yarrow extract at 6: 2: 2 is applied to the damaged skin as in FIG. 2. It turns out that this tends to become small. Therefore, it can be seen that Examples 1 and 2 are more moisturizing effects than Comparative Examples 1 and 2. While the cosmetic composition according to Example 2 contained more mixed extracts of Jasmine extract, Arnica extract and Yarrow extract than Example 1, the moisturizing effect was determined to be smaller, which is believed to be due to the difference in formulation. . This is because emulsion formulations generally have a greater moisturizing effect than gel formulations.

(2) subjective evaluation

The results of the questionnaire about the improvement effect of the dry skin on the test subjects are shown in Table 3 below.

Applicator Respondents Very good Good usually Inadequate Example 1 3 7 4 One Comparative Example 1 One 5 8 One Example 2 2 6 5 2 Comparative Example 2 0 2 9 4

As shown in Table 3, the test subjects can be seen that the site of applying the cosmetic composition according to Examples 1 and 2 is more moisturizing effect than the site of Comparative Examples 1 and 2.

(3) Koniometer measurement result

As shown in FIG. 4, the cosmetic compositions according to Examples 1 and 2 showed a greater increase in moisture content over time than the cosmetic compositions according to Comparative Examples 1 and 2, and the moisturizing effect was greater. To indicate.

Moisturizing cosmetic composition according to the present invention, by giving a moisturizing effect to the skin using an extract of a mixture of three kinds of jasmine extract, arnica extract and yarrow extract, lifestyle factors such as excessive washing or bathing, dry air, pollution Due to environmental factors such as substances and endogenous diseases such as atopic skin or aged skin, the skin having a reduced function as a barrier can be moisturized to protect the skin. In addition, it is possible to maximize the moisturizing effect of the extract by setting the optimum mixing ratio of jasmine extract, arnica extract and yarrow extract. Meanwhile, the moisturizing cosmetic composition according to the present invention can be applied to various formulations such as formulation of oil-in-water emulsion, formulation of gel, and the like.

Claims (3)

Moisturizing cosmetic composition comprising jasmine extract, arnica extract and yarrow extract 0.01 to 60% by weight based on the total weight of the cosmetic composition. The moisturizing cosmetic composition according to claim 1, wherein the weight ratio of the jasmine extract, the arnica extract and the yarrow extract is 5.5 to 6.5: 1.75 to 2.25: 1.75 to 2.25. The moisturizing cosmetic composition of claim 1, wherein the weight ratio of the jasmine extract, the arnica extract, and the yarrow extract is 6: 2: 2.

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