CN106924134A - A kind of Chinese medicine whitening spot-relieving cream and preparation method thereof - Google Patents
A kind of Chinese medicine whitening spot-relieving cream and preparation method thereof Download PDFInfo
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- CN106924134A CN106924134A CN201710114805.2A CN201710114805A CN106924134A CN 106924134 A CN106924134 A CN 106924134A CN 201710114805 A CN201710114805 A CN 201710114805A CN 106924134 A CN106924134 A CN 106924134A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
Abstract
The present invention relates to technical field of skin care, specifically related to a kind of Chinese medicine whitening spot-relieving cream and preparation method thereof, the Chinese medicine whitening spot-relieving cream include base oil, emulsifying agent, thickener, how far alcohols NMF, hyaluronic acid, preservative, Chinese medicine extract A, Chinese medicine extract B and water, the Chinese medicine extract A is obtained by Chinese medicine is extracted, and the Chinese medicine includes pseudo-ginseng, safflower, levisticum, schizonepeta, windproof and radix bupleuri.Chinese medicine whitening spot-relieving cream of the invention can play the damp and hot effect of removal epidermis using pseudo-ginseng, safflower, levisticum, schizonepeta, windproof and radix bupleuri as Chinese medicine compound prescription, color spot be removed from root, and reduce recurrence possibility.
Description
Technical field
The present invention relates to technical field of skin care, and in particular to a kind of Chinese medicine whitening spot-relieving cream and preparation method thereof.
Background technology
Color spot is apt to occur in facial area light brown, and deep brown taupe pigmentation spots, doctor trained in Western medicine thinks that it is a kind of photosensitive dermatitis
Or the variation of photoxic dermatitis, many cases have and chemical article and cosmetics contact history inferior, the oil of cosmetic product such as performer
Adopt or some of family apply some make up that composition occasionally can also cause color spot, postemphasis is shone in usually day illumination, it is malnutritive in addition and its
His factor is likely to cause this disease, and the clear content of copper ion of Most patients increases, it may be possible to the mark of TYR enzyme increased activity.
Therefore most of skin care item are transported and quickening by suppressing melanocyte activity, blocking melanin on the market
The methods such as melanin metabolism realize the effect of freckle removing and whitening, but this is only targetedly to cure the symptoms, not the disease, and user is not having
Have on sound lines using or after stopping using such skin care item, color spot easily recurs.
In the angle of the traditional Chinese medical science, facial colour spot calmness be by spleen kidney deficiency, water it is evil it is it is general gather caused in face, that is to say due to
Epidermis is damp and hot, blood operation is not smooth caused, therefore solves the damp and hot problem of epidermis, is only radical cure color spot originally.
The content of the invention
The purpose of the present invention is directed to above-mentioned deficiency of the prior art, there is provided one kind solves the damp and hot problem of epidermis, color spot
It is difficult the Chinese medicine whitening spot-relieving cream of recurrence, and the preparation method that the Chinese medicine whitening spot-relieving cream is provided.
The purpose of the present invention is achieved through the following technical solutions：
A kind of Chinese medicine whitening spot-relieving cream, the Chinese medicine whitening spot-relieving cream includes the raw material of following parts by weight：
Base oil 10-20 parts
Emulsifying agent 4-7 parts
Thickener 0.8-1.2 parts
10-20 parts of polyalcohols NMF
Hyaluronic acid 0.01-0.05 parts
Preservative 0.3-0.9 parts
15-25 parts of Chinese medicine extract A
4-6 parts of Chinese medicine extract B
Water 30-60 parts
The emulsifying agent by 2.5-3.5 weight portions lecithin, 1-2 weight portion methyl glucoside sesquistearate-EO-20 and
0.5-1.5 weight portion methyl glucosides sesquistearate is constituted, and the Chinese medicine extract A is extracted through decocting by Chinese medicine and made
, the Chinese medicine includes pseudo-ginseng, safflower, levisticum, schizonepeta, windproof and radix bupleuri；The Chinese medicine extract B is the alcohol extracting of dragon's blood
Liquid.
" levisticum, benefaction blood system, the medicine of the wet cold dispelling of wind-dispelling row.The card of all sick wind, such as head term are unable to pitching, and waist and knee can not
Bend and stretch, or numbness pain is difficult to walk, it is numb without all wind is caused with cold, and heat and wet institute hinder；Must be warm with the toil of levisticum, it is living
Take offence blood, cold dispelling of dispelling is evil, therefore《Book on Chinese herbal medicine》Speech can dissipate tinea pedis, change run quickly globefish, treat hernia lump in the abdomen, and subduing inflammation controls the section of harmful wind hundred and attacks pain, fixed few the moon
Cold strongly fragrant headache, it is intended that this." contain substantial amounts of Osthole Osthole, bitter scholar's Coumarins compound, dihydro mountain in levisticum
Celery alcohol（columbianetin）, bergapten（bergapten）, columbianadin（columbia-nadin）.It is excellent
There is the important nutritional ingredient frutus cnidii of selection of land spasmolysis, hypotensive, anti-arrhythmia, enhancing immunologic function and broad-spectrum antiseptic to make
With.Warming kidney and enhancing body, eliminating dampness, wind-dispelling, desinsection.
Schizonepeta taste is put down, and warm in nature, nontoxic, faint scent is dense, enters lung, Liver Channel, has inducing diaphoresis to dissipate wind, promoting eruption, the sore that disappears, the effect of hemostasis,
Acted on obvious inhibiting bacteria and diminishing inflammation with windproof sharing.
Windproof taste is pungent, sweet, slightly warm in nature, with antipyretic, analgesia, calmness, antiallergy, anti-inflammatory, antibacterial, antitumor, raising machine
The pharmacological actions such as body immunity, anticoagulation.
Radix bupleuri bitter, cold nature, Return liver, gallbladder channel, expelled the heat-evil with saturating table, soothing liver-qi stagnation, rise lift yang-energy the effects such as.
Pseudo-ginseng nature and flavor are sweet, slight bitter, temperature, and with The flat liver of heat-clearing, mental-tranquilization, moistening lung preserves youth anti-aging, eliminates and subtract
The effects such as few wrinkle of skin and chloasma.It is particularly suited for beauty, the skin care of women, is the most natural good beauty and skin care of women
Beauty treatment product, its energy anti-aging, protects skin, improves skin appearance, makes skin emolliency and increases elasticity.
Safflower has invigorate blood circulation, the effect of dissolving stasis, can be dredged the channels for nti-freckle, and elimination is deposited on the melanin on skin,
Dredging the channel, acceleration toxin expelling.
Chinese medicine whitening spot-relieving cream of the invention is using pseudo-ginseng, safflower, levisticum, schizonepeta, windproof, radix bupleuri as Chinese medicine compound prescription, energy
The damp and hot effect of removal epidermis is enough played, color spot is removed from root, and reduce recurrence possibility.
The Chinese medicine extract B is dissolved in food grade ethanol and is obtained by 0.1-0.5 weight portion dragon's blood, it is preferable that the Chinese medicine
Extract solution B is 5 weight portions, is dissolved in food grade ethanol by 0.5 weight portion dragon's blood and is obtained.Dragon's blood is sweet, salty, mild-natured, in the present invention
In, with Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, Radix Astragali compounding composition ministerial drug, play the effect of scattered stasis pain, hemostasis, myogenic sore.
In current skin care item, under the epoch of cosmetics overconsumption, cosmetic skin care product have become the No.1 of skin and kill
One of hand, the improper use of cosmetic skin care product can cause the generation of the phenomenons such as allergic, itch, furfur, redness, red blood silk.
Shown according to the Ministry of Public Health 2003 and the statistics of 2004, contact dermatitis is most commonly seen in six major class cosmetic skin care product skin diseases,
And sensibiligen is mainly preservative, spices and essence, surfactant in cosmetic skin care product etc..And Chinese medicine whitening of the invention is light
Spot frost, in addition to it can effectively effect a radical cure color spot problem, moreover it is possible to anti-inflammatory Shu Min, solves most of women at present and excessively uses skin care item band
The allergic problem for coming.
Preferably, the Chinese medicine whitening spot-relieving cream includes the raw material of following parts by weight：
15 parts of base oil
5.5 parts of emulsifying agent
1 part of thickener
15 parts of polyalcohols NMF
0.03 part of hyaluronic acid
0.6 part of preservative
20 parts of Chinese medicine extract A
5 parts of Chinese medicine extract B
30.77 parts of water
Preferably, the Chinese medicine also includes Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.
Radix Angelicae Sinensis, sweet, pungent, hardship is warm in nature, have enrich blood, invigorate blood circulation, the effect of menstruction regulating and pain relieving, moisturize laxation.In whitening of the invention
In light spot frost, Radix Angelicae Sinensis Wheat Protein, by eliminating free radical, suppress superoxide radical cause membrane lipid peroxidatio react and
Radical reaction is gloomy to the complexion caused by free radical retardance or not magnificent have improvement special efficacy；In addition, when giving back containing various
Amino acid, inorganic salts and vitamin, can supplement skin nutrition, promote skin blood circulation, regulation metabolism to control lipid
Metabolin so as to realize the effect of the newborn light spot of the present invention, and can suppress producing again for color spot in the deposition of skin, reduce color
The recurrence rate of spot.
Ligusticum wallichii taste is pungent, it is warm in nature, there are blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.In whitening spot-relieving cream of the invention, Ligusticum wallichii is to skin
The skin circulatory system has good adjustment effect, and its infusion has stronger restraint to some pathogenic dermatophytes；Additionally, river
Rhizome of chuanxiong replenishing vitamins E and can also suppress the activity of tyrosinase, so as to can play therapeutic action to blackspot, freckle, senile plaque expelling.
Corydalis tuber taste is pungent is bitter, warm in nature, has promoting blood circulation, dissipates the stasis of blood, qi-regulating, the effect of analgesic.In whitening spot-relieving cream of the invention, prolong
Hu Suoyu Ligusticum wallichiis are used cooperatively, and can promote pigment cell of skin metabolism, suppress pigment generation, reach light spot effect.
The Radix Astragali is sweet, slightly warm in nature, the effect for having invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation.In whitening of the invention
In light spot frost, the Radix Astragali contains a kind of 20 amino acid and trace element, and with enhancement cell viability, delay skin aging, compact skin
Skin, enhancing cutaneous immunisation power, the effect of anti-inflammation and sterilization.
Radix Glycyrrhizae, it is mild-natured and, have replenish qi to invigorate the spleen, clearing heat and detoxicating, relieving spasm to stop pain, relax the property of medicine effect.In whitening of the invention
In light spot frost, Radix Glycyrrhizae contains protein and several amino acids, refers to class, polysaccharide, tartaric acid, vitamins, trace element etc., to skin
Skin tissue has repair function, can remove the cicatrical or non-cicatrical pigment left after skin lesion self-healing；Except this it
Outward, Radix Glycyrrhizae can also reconcile the property of medicine and toxicity of other Chinese medicines in compound of the present invention, make whitening spot-relieving cream of the invention to human body skin
Skin is substantially nonirritant.
Chinese medicine whitening spot-relieving cream of the invention is removing the damp and hot pseudo-ginseng of epidermis, safflower, levisticum, schizonepeta, windproof and radix bupleuri
Be monarch drug in a prescription, with the Radix Angelicae Sinensis of promoting blood circulation to remove blood stasis, Ligusticum wallichii, corydalis tuber and the Radix Astragali as ministerial drug, with sensible Radix Glycyrrhizae of detoxifying as assistant makes, monarch drug in a prescription with
Take good care of based on human body, can fundamentally solve skin produce color spot the reason for, reduce color spot recurrence possibility；Ministerial drug is with promoting the circulation of qi
Based on promoting blood circulation, blood circulation can be effectively rapidly promoted, color spot and the activity of suppression chromatophore that removal has been produced；Assistant make with
Reconcile based on drug effect, drug effect can be promoted, Chinese medicine whitening spot-relieving cream of the invention is easy to absorption of human body, three complements each other,
Realize the effect of Whitening, spot.
Preferably, every 10 weight portion Chinese medicine extract A is extracted by decocting by 9-36 weight portions Chinese medicine and is obtained.It is more highly preferred to
, the preparation method of every 10 weight portion Chinese medicine extract A is：Each Chinese medicine weighs 1.25 weight portions and is added to 50 weight portion water
In, cold filtration concentration is boiled, obtain the 10 weight portion Chinese medicine extract A.The preferred embodiment can more make each Chinese medicine effective.
Preferably, the base oil is made up of 7-13 weight portions camellia oil and 3-7 weight portion shea butters.Camellia oil nutrition
It is abundant, fatty acids（Unrighted acid 93%, preferably oleic acid 82%, linoleic acid 11%）, camellianin, Tea Polyphenols, saponin, tan
Matter, and the squalene rich in antioxidant and with anti-inflammatory effect, with moisturizing, moisten, it is promoting blood circulation and removing blood stasis the effects such as；Shea butter
Soft and moist children is sliding for quality, is maximally effective natural moisture preserving product, promotes cytothesis and repairs effect of skin moisture film, can be relaxed with tender
Slow skin；It is further preferable that the base oil is by camellia oil and shea butter by weight 2:1 ratio composition, it is of the invention
Base oil can realize certain water lock effect, strengthen the moisture-keeping function of NMF, promote Chinese medicine of the invention by percutaneous absorption.
Preferably, the emulsifying agent is by 2.5-3.5 weight portions lecithin, 1-2 weight portion methyl glucoside times semi-solid fats
Acid esters-EO-20（Abbreviation SSE20）With 0.5-1.5 weight portion methyl glucoside sesquistearates（Abbreviation SS）Composition.More
Preferably, emulsifying agent of the invention is by lecithin, methyl glucoside sesquistearate-EO-20 and methyl glucoside times
Semi-solid fat acid esters is by weight 3:1.5:1 ratio composition, emulsifying agent of the invention can strengthen it is of the invention breast easily spreadability,
Permeability, breast is applied to skin upper erengy band and carrys out smooth refreshing experience.
Preferably, the polyalcohols NMF is by 2.5-7.5 parts by weight of glycerin and 7.5-12.5 weight portion butanediol groups
Into.It is further preferable that polyalcohols NMF of the invention is by glycerine and butanediol by weight 1:2 ratio composition, glycerine
Belong to semi-polarity molecule, thus it is safer to skin, excitant is small during low concentration, when being shared with Sodium Hyaluronate, moisturizing effect
Fruit is more preferably；Butanediol moisture retention, security, permeability compared with（Propane diols）Well, in for the present invention, the compounding with Sodium Hyaluronate
Moistening effect is more excellent.
Preferably, the thickener is polyacrylate cross-linked polymeric species thickener.It is further preferable that the thickener
It is SEPIMAX ZEN polyacrylate cross-linked polymer -6.Thickener of the invention can play good thickening emulsification effect
Really, the stability and sense of touch of present invention breast are lifted.
Preferably, the preservative is by 0.05-0.15 weight portions Sensiva SC50 and 0.25-0.75 weight portion benzene oxygen second
Alcohol is constituted.It is further preferable that the preservative is by Sensiva SC50 and Phenoxyethanol in mass ratio 1:5 ratio composition.This
The bacteriostasis that the preservative of invention is carried with reference to polyalcohols NMF of the present invention, can play good antiseptic effect, and
And will not excessively damage the drug effect of Chinese herb compound of the present invention.
Preferably, the Chinese medicine whitening spot-relieving cream also include 0.1-2 weight portions flores aurantii fragrant, 0.01-0.2 weight portions borneol and
1-5 weight portion 4- methoxysalicylic acid potassium.
Preferably, fragrant and borneol the weight ratio of the flores aurantii is 10:1.The present invention is dissolved in flores aurantii perfume by by borneol, orange
The fragrance of a flower and borneol primarily serve the fragrance for improving Chinese medicine whitening spot-relieving cream of the present invention.
The methoxysalicylic acid potassium, also known as 4MSK, are medicinal whitening compositions, with the generation for suppressing melanin, are prevented
The color spot generated by Exposure to Sunlight, the effect of freckle.4MSK not only has the effect for suppressing melanin generation, can more adjust angling mistake
The situation of Cheng Bushun.Compounded with Chinese medicine compound prescription of the invention, it is possible to increase the efficiency that comes into force of Chinese medicine whitening spot-relieving cream of the present invention, soon
Speed removes color spot.
A kind of preparation method of Chinese medicine whitening spot-relieving cream as described above, comprises the following steps：
Comprise the following steps：（1）Will thickener, polyalcohol, hyaluronic acid and water mix after be heated to 70-90 DEG C, homogeneous 5min,
Insulation 30-60min, obtains A and mixes liquid；（2）70-90 DEG C is heated to after emulsifying agent and base oil are mixed, then in stirring
Under conditions of, preservative is added, homogeneous 5-15min is stirred, obtain B and mix liquid；（3）A is mixed into liquid and is cooled to 35-55
DEG C, add B to mix liquid and other raw materials in mixing liquid toward A, vacuumize, stirring homogeneous 5-15min, you can filtering and discharging,
The Chinese medicine whitening spot-relieving cream is obtained.
If other raw materials include that flores aurantii perfume and borneol, the borneol are used in being previously dissolved in flores aurantii perfume；If including
4MSK, 4MSK are used in being previously dissolved in part water, it is preferable that the 4MSK is 1 with the weight ratio of the part water:1.
It is further preferable that the Chinese medicine whitening spot-relieving cream is made up of the raw material of following percentage by weight：
Camellia oil 10%
Shea butter 5%
SS 1%
SSE20 1.5%
Lecithin 3%
Polyacrylate cross-linked polymer -6 1%
Glycerine 5%
Butanediol 10%
Hyaluronic acid 0.03%
Sensiva SC50 0.1%
Phenoxyethanol 0.5%
Chinese medicine extract A 20%
Chinese medicine extract B 5%
Water 33.77%
Flores aurantii perfume (or spice) 1%
Borneol 0.1%
4MSK 3%；
Every 10 weight portion Chinese medicine extract A prepares prepared by the following method：Take pseudo-ginseng, safflower, levisticum, schizonepeta, windproof, bavin
Recklessly, Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and each 1.25 weight portion of Radix Glycyrrhizae, are added in 50 weight portion water, cooled by boiling
Filter concentration, obtains 10 described weight portion Chinese medicine extract A.
Beneficial effects of the present invention：1st, Chinese medicine whitening spot-relieving cream of the invention with pseudo-ginseng, safflower, levisticum, schizonepeta, it is windproof and
Radix bupleuri can play the damp and hot effect of removal epidermis as Chinese medicine compound prescription, and color spot is removed from root, and it is possible to reduce recurrence
Property；2nd, Chinese medicine whitening spot-relieving cream of the invention, in addition to it can effectively effect a radical cure color spot problem, moreover it is possible to anti-inflammatory Shu Min, solves big at present
The allergic problem that most women are excessively brought using skin care item；3rd, Sodium Hyaluronate has very powerful water holding, water lock ability,
It is prevalent in intercellular matrix, in human body skin skin corium content at most, with skin moisture content is kept, makes skin light
The effect of sliding and high resilience, strengthens the effect of the eliminating toxic dampness and heat of Chinese medicine compound prescription.
Specific embodiment
The invention will be further described with the following Examples.
Embodiment 1
A kind of Chinese medicine whitening spot-relieving cream, including following parts by weight raw material：
15 parts of base oil
5.5 parts of emulsifying agent
1 part of thickener
15 parts of polyalcohols NMF
0.03 part of hyaluronic acid
0.6 part of preservative
20 parts of Chinese medicine extract A
5 parts of Chinese medicine extract B
30.77 parts of water
The base oil is shea butter, and the emulsifying agent is lecithin, and the thickener is Carbomer, and the polyalcohols are protected
Humectant is butanediol, and the preservative is Phenoxyethanol；The Chinese medicine extract A is obtained by Chinese medicine is extracted, the Chinese medicine package
Pseudo-ginseng, safflower, levisticum, schizonepeta, windproof and radix bupleuri are included, the 10 weight portion Chinese medicine extract A is passed through by 22.5 weight portion Chinese medicines
Decocting is extracted and is obtained, and the Chinese medicine extract B is dissolved in food grade ethanol and is obtained by the dragon's blood of 0.3 weight portion.
Embodiment 2
The present embodiment is with the difference of embodiment 1：
The base oil is by camellia oil and shea butter by weight 2:1 ratio composition；The emulsifying agent is by lecithin, methyl
Glucoside sesquistearate-EO-20 and methyl glucoside sesquistearate are by weight 3:1.5:1 ratio group
Into；The polyalcohols NMF is by glycerine and butanediol by weight 1:2 ratio composition；The thickener is polyacrylic acid
Ester cross-linked polymer -6；The preservative is by Sensiva SC50 and Phenoxyethanol in mass ratio 1:5 ratio composition.
Embodiment 3
The present embodiment is with the difference of embodiment 2：
The 10 weight portion Chinese medicine extract A prepares prepared by the following method：Take pseudo-ginseng, safflower, levisticum, schizonepeta, windproof, bavin
Recklessly, Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and each 1.25 weight portion of Radix Glycyrrhizae, are added in 50 weight portion water, cooled by boiling
Filter concentration, obtains 10 described weight portion Chinese medicine extract A.
Embodiment 4
The present embodiment is with the difference of embodiment 3：
Also include fragrant 5 weight portion dragon's blood extract solutions, 1 weight portion flores aurantii, 0.1 weight portion borneol and 3 weight portion 4- methoxysalicylics
Sour potassium；The parts by weight of the water are 33.77 parts.
Embodiment 5
A kind of Chinese medicine whitening spot-relieving cream, including following parts by weight raw material：
10 parts of base oil
4 parts of emulsifying agent
0.8 part of thickener
10 parts of polyalcohols NMF
0.01 part of hyaluronic acid
0.3 part of preservative
15 parts of Chinese medicine extract A
4 parts of Chinese medicine extract B
30 parts of water
Flores aurantii is fragrant 0.1 part
0.01 part of borneol
1 part of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include pseudo-ginseng, safflower, levisticum, schizonepeta, windproof, radix bupleuri,
Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is：Each Chinese medicine weighs 1
Weight portion is added in 50 weight portion water, boils cold filtration concentration, obtains the 10 weight portion Chinese medicine extract A；In described
Medicament extracting solution B is dissolved in food grade ethanol and is obtained by the dragon's blood of 0.1 weight portion.
The base oil is made up of 7 weight portion camellia oils and 3 weight portion shea butters, and the emulsifying agent is by 2.5 weight portions
Lecithin, 1 weight portion methyl glucoside sesquistearate-EO-2,0.5 weight portion methyl glucoside sesquistearate
Composition, the thickener is polyacrylate cross-linked polymer -6, the polyalcohols NMF by 2.5 parts by weight of glycerin and
7.5 weight portion butanediols are constituted, and the preservative is by 0.05 weight portion Sensiva SC50 and 0.25 weight portion Phenoxyethanol group
Into.
Embodiment 6
A kind of Chinese medicine whitening spot-relieving cream, including following parts by weight raw material：
20 parts of base oil
7 parts of emulsifying agent
1.2 parts of thickener
20 parts of polyalcohols NMF
0.05 part of hyaluronic acid
0.9 part of preservative
25 parts of Chinese medicine extract A
6 parts of Chinese medicine extract B
60 parts of water
Flores aurantii is fragrant 2 parts
0.2 part of borneol
5 parts of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include pseudo-ginseng, safflower, levisticum, schizonepeta, windproof, radix bupleuri,
Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is：Each Chinese medicine weighs 4
Weight portion is added in 50 weight portion water, boils cold filtration concentration, obtains the 10 weight portion Chinese medicine extract A；In described
Medicament extracting solution B is dissolved in food grade ethanol and is obtained by the dragon's blood of 0.5 weight portion.
The base oil is made up of 6 weight portion camellia oils and 4 weight portion shea butters, and the emulsifying agent is by 3.5 weight portions
Lecithin, 2 weight portion methyl glucoside sesquistearate-EO-2,1.5 weight portion methyl glucoside sesquistearates
Composition, the thickener is polyacrylate cross-linked polymer -6, the polyalcohols NMF by 7.5 parts by weight of glycerin and
12.5 weight portion butanediols are constituted, and the preservative is by 0.15 weight portion Sensiva SC50 and 0.75 weight portion Phenoxyethanol group
Into.
Embodiment 7
A kind of Chinese medicine whitening spot-relieving cream, including following parts by weight raw material：
12 parts of base oil
5 parts of emulsifying agent
0.9 part of thickener
13 parts of polyalcohols NMF
0.02 part of hyaluronic acid
0.5 part of preservative
17 parts of Chinese medicine extract A
4.5 parts of Chinese medicine extract B
40 parts of water
Flores aurantii is fragrant 0.3 part
0.03 part of borneol
2 parts of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include pseudo-ginseng, safflower, levisticum, schizonepeta, windproof, radix bupleuri,
Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is：Each Chinese medicine weighs 2
Weight portion is added in 50 weight portion water, boils cold filtration concentration, obtains the 10 weight portion Chinese medicine extract A；In described
Medicament extracting solution B is dissolved in food grade ethanol and is obtained by the dragon's blood of 0.4 weight portion.
The base oil is made up of 8 weight portion camellia oils and 4 weight portion shea butters, and the emulsifying agent is by 2.5 weight portions
Lecithin, 2 weight portion methyl glucoside sesquistearate-EO-2,0.5 weight portion methyl glucoside sesquistearate
Composition, the thickener is polyacrylate cross-linked polymer -6, and the polyalcohols NMF is by 7 parts by weight of glycerin and 6 weights
Amount part butanediol composition, the preservative is made up of 0.05 weight portion Sensiva SC50 and 0.45 weight portion Phenoxyethanol.
Embodiment 8
A kind of Chinese medicine whitening spot-relieving cream, including following parts by weight raw material：
17 parts of base oil
5 parts of emulsifying agent
1.1 parts of thickener
17 parts of polyalcohols NMF
0.04 part of hyaluronic acid
0.8 part of preservative
23 parts of Chinese medicine extract A
4.5 parts of Chinese medicine extract B
55 parts of water
6 parts of dragon's blood extract solution
Flores aurantii is fragrant 1.5 parts
0.15 part of borneol
4 parts of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include pseudo-ginseng, safflower, levisticum, schizonepeta, windproof, radix bupleuri,
Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is：Each Chinese medicine weighs 3
Weight portion is added in 50 weight portion water, boils cold filtration concentration, obtains the 10 weight portion Chinese medicine extract A；In described
Medicament extracting solution B is dissolved in food grade ethanol and is obtained by the dragon's blood of 0.2 weight portion.
The base oil is made up of 12 weight portion camellia oils and 5 weight portion shea butters, and the emulsifying agent is by 3.5 weight portions
Lecithin, 1 weight portion methyl glucoside sesquistearate-EO-2,0.5 weight portion methyl glucoside sesquistearate
Composition, the thickener is polyacrylate cross-linked polymer -6, and the polyalcohols NMF is by 11 parts by weight of glycerin and 6 weights
Amount part butanediol composition, the preservative is made up of 0.1 weight portion Sensiva SC50 and 0.7 weight portion Phenoxyethanol.
Carrying out whitening effect test to the Chinese medicine whitening spot-relieving cream of embodiment 1-8 respectively, it is 20 at the age that experimental subjects is~
35 years old, there is the women 90 of color spot or other speckles on the face, be arbitrarily divided into 10 Yuans one group, altogether 8 experimental groups and 1 control
Group；Experimental technique applies face using the Chinese medicine whitening spot-relieving cream every night for the women of experimental group, and control group women uses tradition every night
Tartaric acid cleawhite pack applies face, and usage cycles are 30 days, and skin was checked to those dermal melanin testers for women every 10 days
Middle melanin content, and the average value of melanin inhibiting rate is calculated according to the following formula --- melanin inhibiting rate=（Control group skin
Skin melanin content-experimental group dermal melanin content）/ control group dermal melanin content * 100%.Obtain the experiment knot of following table
Really.
By the observation of 30 days, Chinese medicine whitening spot-relieving cream of the invention had obvious effect to color spot, and skin colourity is obtained
It is obvious to decline.This explanation whitening spot-relieving cream of the invention further promotes the angle containing melanocyte in addition to suppressing the synthesis of melanin
Cell plastid comes off, or is restricted the melanocyte Melanogenic ability of product, so as to reach skin whitening effect.
Finally it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than the present invention is protected
The limitation of scope is protected, although being explained to the present invention with reference to preferred embodiment, one of ordinary skill in the art should
Work as understanding, technical scheme can be modified or equivalent, without deviating from the reality of technical solution of the present invention
Matter and scope.
Claims (10)
1. a kind of Chinese medicine whitening spot-relieving cream, it is characterised in that：The Chinese medicine whitening spot-relieving cream includes the raw material of following parts by weight：
Base oil 10-20 parts
Emulsifying agent 4-7 parts
Thickener 0.8-1.2 parts
10-20 parts of polyalcohols NMF
Hyaluronic acid 0.01-0.05 parts
15-25 parts of Chinese medicine extract A
4-6 parts of Chinese medicine extract B
Water 20-40 parts
The emulsifying agent by 2.5-3.5 weight portions lecithin, 1-2 weight portion methyl glucoside sesquistearate-EO-20 and
0.5-1.5 weight portion methyl glucosides sesquistearate is constituted, and the Chinese medicine extract A is extracted through decocting by Chinese medicine and made
, the Chinese medicine includes pseudo-ginseng, safflower, levisticum, schizonepeta, windproof and radix bupleuri；The Chinese medicine extract B is the alcohol extracting of dragon's blood
Liquid.
2. a kind of Chinese medicine whitening spot-relieving cream according to claim 1, it is characterised in that：Original including following parts by weight
Material：
15 parts of base oil
5.5 parts of emulsifying agent
1 part of thickener
15 parts of polyalcohols NMF
0.03 part of hyaluronic acid
0.6 part of preservative
20 parts of Chinese medicine extract A
5 parts of Chinese medicine extract B
30.77 parts of water.
3. a kind of Chinese medicine whitening spot-relieving cream according to claim 1, it is characterised in that：The Chinese medicine also includes Radix Angelicae Sinensis, river
Rhizome of chuanxiong, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.
4. a kind of Chinese medicine whitening spot-relieving cream according to claim 1 or 3, it is characterised in that：Every 10 weight portion traditional Chinese medicine extraction
Liquid A is extracted by decocting by 9-36 weight portions Chinese medicine and is obtained.
5. a kind of Chinese medicine whitening spot-relieving cream according to claim 1-3 any one, it is characterised in that：The base oil by
7-13 weight portions camellia oil and 3-7 weight portions shea butter are constituted.
6. a kind of Chinese medicine whitening spot-relieving cream according to claim 1-3 any one, it is characterised in that：The emulsifying agent by
3 weight portion lecithin, 1.5 weight portion methyl glucoside sesquistearate-EO-20 and 1 weight portion methyl glucoside times
Semi-solid fat acid esters is constituted.
7. a kind of Chinese medicine whitening spot-relieving cream according to claim 1-3 any one, it is characterised in that：The polyalcohols
NMF is made up of 2.5-7.5 parts by weight of glycerin and 7.5-12.5 weight portion butanediols, and the thickener is handed over for polyacrylate
Linked polymer class thickener.
8. a kind of Chinese medicine whitening spot-relieving cream according to claim 1-3 any one, it is characterised in that：Also include anti-corrosion
Agent, the preservative Sensiva SC50 and Phenoxyethanol are by weight 1:5 ratio composition.
9. a kind of Chinese medicine whitening spot-relieving cream according to claim 1-3 any one, it is characterised in that：The Chinese medicine whitening
Light spot frost also includes fragrant 1-2 weight portions flores aurantii, 0.01-0.2 weight portions borneol and 1-5 weight portion 4- methoxysalicylic acid potassium.
10. the preparation method of a kind of Chinese medicine whitening spot-relieving cream as described in claim any one of 1-9, it is characterised in that：Including
Following steps：（1）70-90 DEG C is heated to after thickener, polyalcohol, hyaluronic acid and water are mixed, homogeneous 5min is incubated 30-
60min, obtains A and mixes liquid；（2）70-90 DEG C is heated to after emulsifying agent and base oil are mixed, then in the condition of stirring
Under, preservative is added, homogeneous 5-15min is stirred, obtain B and mix liquid；（3）A is mixed into liquid and is cooled to 35-55 DEG C, toward A phases
Add B to mix liquid and other raw materials in mixed liquor, vacuumize, stirring homogeneous 5-15min, you can filtering and discharging is obtained described
Chinese medicine whitening spot-relieving cream.
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| CN201710114805.2A CN106924134A (en) | 2017-02-28 | 2017-02-28 | A kind of Chinese medicine whitening spot-relieving cream and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109288753A (en) * | 2018-11-15 | 2019-02-01 | 广州博科健康科技集团有限公司 | A kind of whitening spot-relieving cream and preparation method thereof |
| CN110037972A (en) * | 2019-05-14 | 2019-07-23 | 广州法蒂芙生物科技有限公司 | A kind of Whitening, spot stoste and its compounding method |
| CN112587470A (en) * | 2021-01-11 | 2021-04-02 | 薄湘 | Preparation process of ginseng whitening and freckle removing cream |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1448161A (en) * | 2002-03-30 | 2003-10-15 | 张善领 | Process formula of skin-care liquid |
| CN104188857A (en) * | 2014-08-22 | 2014-12-10 | 广东药学院 | Traditional Chinese medicine skin-whitening fleck-banishing cream and preparation method thereof |
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2017
- 2017-02-28 CN CN201710114805.2A patent/CN106924134A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1448161A (en) * | 2002-03-30 | 2003-10-15 | 张善领 | Process formula of skin-care liquid |
| CN104188857A (en) * | 2014-08-22 | 2014-12-10 | 广东药学院 | Traditional Chinese medicine skin-whitening fleck-banishing cream and preparation method thereof |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109288753A (en) * | 2018-11-15 | 2019-02-01 | 广州博科健康科技集团有限公司 | A kind of whitening spot-relieving cream and preparation method thereof |
| CN110037972A (en) * | 2019-05-14 | 2019-07-23 | 广州法蒂芙生物科技有限公司 | A kind of Whitening, spot stoste and its compounding method |
| CN112587470A (en) * | 2021-01-11 | 2021-04-02 | 薄湘 | Preparation process of ginseng whitening and freckle removing cream |
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Application publication date: 20170707 |