CN106890120A - A kind of Chinese medicine Whitening, spot breast and preparation method thereof - Google Patents

A kind of Chinese medicine Whitening, spot breast and preparation method thereof Download PDF

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Publication number
CN106890120A
CN106890120A CN201710114804.8A CN201710114804A CN106890120A CN 106890120 A CN106890120 A CN 106890120A CN 201710114804 A CN201710114804 A CN 201710114804A CN 106890120 A CN106890120 A CN 106890120A
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CN
China
Prior art keywords
chinese medicine
parts
spot
whitening
weight portion
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CN201710114804.8A
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Chinese (zh)
Inventor
王世东
刘显曜
刘逸华
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GLOBAL COSMETICS (CHINA) CO Ltd
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GLOBAL COSMETICS (CHINA) CO Ltd
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Priority to CN201710114804.8A priority Critical patent/CN106890120A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
    • A61K2800/72Hypo-allergenic

Abstract

The present invention relates to technical field of skin care, specifically related to a kind of Chinese medicine Whitening, spot breast and preparation method thereof, Chinese medicine Whitening, spot breast include base oil, emulsifying agent, thickener, how far alcohols NMF, hyaluronic acid, preservative, Chinese medical extract and water, the Chinese medicine extract A is obtained by Chinese medicine is extracted, and the Chinese medicine includes levisticum, schizonepeta, windproof and radix bupleuri.Chinese medicine Whitening, spot breast of the invention can play the damp and hot effect of removal epidermis using levisticum, schizonepeta, windproof and radix bupleuri as Chinese medicine compound prescription, color spot be removed from root, and reduce recurrence possibility.

Description

A kind of Chinese medicine Whitening, spot breast and preparation method thereof
Technical field
The present invention relates to technical field of skin care, and in particular to a kind of Chinese medicine Whitening, spot breast and preparation method thereof.
Background technology
Color spot is apt to occur in facial area light brown, and deep brown taupe pigmentation spots, doctor trained in Western medicine thinks that it is a kind of photosensitive dermatitis Or the variation of photoxic dermatitis, many cases have and chemical article and cosmetics contact history inferior, the oil of cosmetic product such as performer Adopt or some of family apply some make up that composition occasionally can also cause color spot, postemphasis is shone in usually day illumination, it is malnutritive in addition and its His factor is likely to cause this disease, and the clear content of copper ion of Most patients increases, it may be possible to the mark of TYR enzyme increased activity.
Therefore most of skin care item are transported and quickening by suppressing melanocyte activity, blocking melanin on the market The methods such as melanin metabolism realize the effect of freckle removing and whitening, but this is only targetedly to cure the symptoms, not the disease, and user is not having Have on sound lines using or after stopping using such skin care item, color spot easily recurs.
In the angle of the traditional Chinese medical science, facial colour spot calmness be by spleen kidney deficiency, water it is evil it is it is general gather caused in face, that is to say due to Epidermis is damp and hot, blood operation is not smooth caused, therefore solves the damp and hot problem of epidermis, is only radical cure color spot originally.
The content of the invention
The purpose of the present invention is directed to above-mentioned deficiency of the prior art, there is provided one kind solves the damp and hot problem of epidermis, color spot It is difficult the Chinese medicine Whitening, spot breast of recurrence, and the preparation method that Chinese medicine Whitening, spot breast is provided.
The purpose of the present invention is achieved through the following technical solutions:
A kind of Chinese medicine Whitening, spot breast, the raw material of the Chinese medicine Whitening, spot breast including following parts by weight:
Base oil 10-20 parts
Emulsifying agent 4-7 parts
Thickener 0.1-0.5 parts
10-20 parts of polyalcohols NMF
Hyaluronic acid 0.01-0.05 parts
Preservative 0.3-0.9 parts
15-25 parts of Chinese medicine extract A
4-6 parts of Chinese medicine extract B
Water 30-60 parts
The Chinese medicine extract A by Chinese medicine through decocting extract be obtained, the Chinese medicine include levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.
" levisticum, benefaction blood system, the medicine of the wet cold dispelling of wind-dispelling row.The card of all sick wind, such as head term are unable to pitching, and waist and knee can not Bend and stretch, or numbness pain is difficult to walk, it is numb without all wind is caused with cold, and heat and wet institute hinder;Must be warm with the toil of levisticum, it is living Take offence blood, cold dispelling of dispelling is evil, therefore《Book on Chinese herbal medicine》Speech can dissipate tinea pedis, change run quickly globefish, treat hernia lump in the abdomen, and subduing inflammation controls the section of harmful wind hundred and attacks pain, fixed few the moon Cold strongly fragrant headache, it is intended that this." contain substantial amounts of Osthole Osthole, bitter scholar's Coumarins compound, dihydro mountain in levisticum Celery alcohol(columbianetin), bergapten(bergapten), columbianadin(columbia-nadin).It is excellent There is the important nutritional ingredient frutus cnidii of selection of land spasmolysis, hypotensive, anti-arrhythmia, enhancing immunologic function and broad-spectrum antiseptic to make With.Warming kidney and enhancing body, eliminating dampness, wind-dispelling, desinsection.
Schizonepeta taste is put down, and warm in nature, nontoxic, faint scent is dense, enters lung, Liver Channel, has inducing diaphoresis to dissipate wind, promoting eruption, the sore that disappears, the effect of hemostasis, Acted on obvious inhibiting bacteria and diminishing inflammation with windproof sharing.
Windproof taste is pungent, sweet, slightly warm in nature, with antipyretic, analgesia, calmness, antiallergy, anti-inflammatory, antibacterial, antitumor, raising machine The pharmacological actions such as body immunity, anticoagulation.
Radix bupleuri bitter, cold nature, Return liver, gallbladder channel, expelled the heat-evil with saturating table, soothing liver-qi stagnation, rise lift yang-energy the effects such as.
Chinese medicine Whitening, spot breast of the invention can play removal using levisticum, schizonepeta, windproof and radix bupleuri as Chinese medicine compound prescription The damp and hot effect of epidermis, removes color spot, and reduce recurrence possibility from root.
Radix Angelicae Sinensis, sweet, pungent, hardship is warm in nature, have enrich blood, invigorate blood circulation, the effect of menstruction regulating and pain relieving, moisturize laxation.In whitening of the invention In light spot breast, Radix Angelicae Sinensis Wheat Protein, by eliminating free radical, suppress superoxide radical cause membrane lipid peroxidatio react and Radical reaction is gloomy to the complexion caused by free radical retardance or not magnificent have improvement special efficacy;In addition, when giving back containing various Amino acid, inorganic salts and vitamin, can supplement skin nutrition, promote skin blood circulation, regulation metabolism to control lipid Metabolin so as to realize the effect of the newborn light spot of the present invention, and can suppress producing again for color spot in the deposition of skin, reduce color The recurrence rate of spot.
Ligusticum wallichii taste is pungent, it is warm in nature, there are blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.In Whitening, spot of the invention breast, Ligusticum wallichii is to skin The skin circulatory system has good adjustment effect, and its infusion has stronger restraint to some pathogenic dermatophytes;Additionally, river Rhizome of chuanxiong replenishing vitamins E and can also suppress the activity of tyrosinase, so as to can play therapeutic action to blackspot, freckle, senile plaque expelling.
Corydalis tuber taste is pungent is bitter, warm in nature, has promoting blood circulation, dissipates the stasis of blood, qi-regulating, the effect of analgesic.In Whitening, spot of the invention breast, prolong Hu Suoyu Ligusticum wallichiis are used cooperatively, and can promote pigment cell of skin metabolism, suppress pigment generation, reach light spot effect.
The Radix Astragali is sweet, slightly warm in nature, the effect for having invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation.In whitening of the invention In light spot breast, the Radix Astragali contains a kind of 20 amino acid and trace element, and with enhancement cell viability, delay skin aging, compact skin Skin, enhancing cutaneous immunisation power, the effect of anti-inflammation and sterilization.
Radix Glycyrrhizae, it is mild-natured and, have replenish qi to invigorate the spleen, clearing heat and detoxicating, relieving spasm to stop pain, relax the property of medicine effect.In whitening of the invention In light spot breast, Radix Glycyrrhizae contains protein and several amino acids, refers to class, polysaccharide, tartaric acid, vitamins, trace element etc., to skin Skin tissue has repair function, can remove the cicatrical or non-cicatrical pigment left after skin lesion self-healing;Except this it Outward, Radix Glycyrrhizae can also reconcile the property of medicine and toxicity of other Chinese medicines in compound of the present invention, make Whitening, spot breast of the invention to human body skin Skin is substantially nonirritant.
Chinese medicine Whitening, spot breast of the invention is monarch drug in a prescription to remove the damp and hot levisticum of epidermis, schizonepeta, windproof and radix bupleuri, with work Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber and the Radix Astragali that blood dissipates the stasis of blood are ministerial drug, and with sensible Radix Glycyrrhizae of detoxifying as assistant makes, monarch drug in a prescription is to take good care of human body It is main, the reason for fundamentally solving skin and produce color spot, reduce the possibility of color spot recurrence;Ministerial drug based on the promoting flow of qi and blood circulation, Blood circulation can be effectively rapidly promoted, color spot and the activity of suppression chromatophore that removal has been produced;Assistant makes to reconcile drug effect Based on, drug effect can be promoted, Chinese medicine Whitening, spot breast of the invention is easy to absorption of human body, three complements each other, and realizes whitening The effect of light spot.
The Chinese medicine extract B is dissolved in food grade ethanol and is obtained by 0.1-0.5 weight portion dragon's blood, it is preferable that the Chinese medicine Extract solution B is 5 weight portions, is dissolved in food grade ethanol by 0.5 weight portion dragon's blood and is obtained.Dragon's blood is sweet, salty, mild-natured, in the present invention In, with Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, Radix Astragali compounding composition ministerial drug, play the effect of scattered stasis pain, hemostasis, myogenic sore.
In current skin care item, under the epoch of cosmetics overconsumption, cosmetic skin care product have become the No.1 of skin and kill One of hand, the improper use of cosmetic skin care product can cause the generation of the phenomenons such as allergic, itch, furfur, redness, red blood silk. Shown according to the Ministry of Public Health 2003 and the statistics of 2004, contact dermatitis is most commonly seen in six major class cosmetic skin care product skin diseases, And sensibiligen is mainly preservative, spices and essence, surfactant in cosmetic skin care product etc..And Chinese medicine whitening of the invention is light Spot breast, in addition to it can effectively effect a radical cure color spot problem, moreover it is possible to anti-inflammatory Shu Min, solves most of women at present and excessively uses skin care item band The allergic problem for coming.
Preferably, the raw material of the Chinese medicine Whitening, spot breast including following parts by weight:
15 parts of base oil
5.5 parts of emulsifying agent
0.3 part of thickener
15 parts of polyalcohols NMF
0.03 part of hyaluronic acid
0.6 part of preservative
20 parts of Chinese medicine extract A
5 parts of Chinese medicine extract B
31.47 parts of water
Preferably, every 10 weight portion Chinese medicine extract A is extracted by decocting by 9-36 weight portions Chinese medicine and is obtained.It is further preferable that The preparation method of every 10 weight portion Chinese medicine extract A is:Each Chinese medicine weighs 1.25 weight portions and is added in 50 weight portion water, Cold filtration concentration is boiled, the 10 weight portion Chinese medicine extract A is obtained.The preferred embodiment can more make each Chinese medicine effective.
Preferably, the base oil is made up of 7-13 weight portions camellia oil and 3-7 weight portion shea butters.Camellia oil nutrition It is abundant, fatty acids(Unrighted acid 93%, preferably oleic acid 82%, linoleic acid 11%), camellianin, Tea Polyphenols, saponin, tan Matter, and the squalene rich in antioxidant and with anti-inflammatory effect, with moisturizing, moisten, it is promoting blood circulation and removing blood stasis the effects such as;Shea butter Soft and moist children is sliding for quality, is maximally effective natural moisture preserving product, promotes cytothesis and repairs effect of skin moisture film, can be relaxed with tender Slow skin;It is further preferable that the base oil is by camellia oil and shea butter by weight 2:1 ratio composition, it is of the invention Base oil can realize certain water lock effect, strengthen the moisture-keeping function of NMF, promote Chinese medicine of the invention by percutaneous absorption.
Preferably, the emulsifying agent is by 2.5-3.5 weight portions lecithin, 1-2 weight portion methyl glucoside times semi-solid fats Acid esters-EO-20(Abbreviation SSE20)With 0.5-1.5 weight portion methyl glucoside sesquistearates(Abbreviation SS)Composition.More Preferably, emulsifying agent of the invention is by lecithin, methyl glucoside sesquistearate-EO-20 and methyl glucoside times Semi-solid fat acid esters is by weight 3:1.5:1 ratio composition, emulsifying agent of the invention can strengthen it is of the invention breast easily spreadability, Permeability, breast is applied to skin upper erengy band and carrys out smooth refreshing experience.
Preferably, the polyalcohols NMF is by 2.5-7.5 parts by weight of glycerin and 7.5-12.5 weight portion butanediol groups Into.It is further preferable that polyalcohols NMF of the invention is by glycerine and butanediol by weight 1:2 ratio composition, glycerine Belong to semi-polarity molecule, thus it is safer to skin, excitant is small during low concentration, when being shared with Sodium Hyaluronate, moisturizing effect Fruit is more preferably;Butanediol moisture retention, security, permeability compared with(Propane diols)Well, in for the present invention, the compounding with Sodium Hyaluronate Moistening effect is more excellent.
Preferably, the thickener is polyacrylate cross-linked polymeric species thickener.It is further preferable that the thickener It is SEPIMAX ZEN polyacrylate cross-linked polymer -6.Thickener of the invention can play good thickening emulsification effect Really, the stability and sense of touch of Chinese medicine Whitening, spot breast of the present invention are lifted.
Preferably, the preservative is by 0.05-0.15 weight portions Sensiva SC50 and 0.25-0.75 weight portion benzene oxygen second Alcohol is constituted.It is further preferable that the preservative is by Sensiva SC50 and Phenoxyethanol in mass ratio 1:5 ratio composition.This The bacteriostasis that the preservative of invention is carried with reference to polyalcohols NMF of the present invention, can play good antiseptic effect, and And will not excessively damage the drug effect of Chinese herb compound of the present invention.
Preferably, Chinese medicine Whitening, spot breast also include fragrant 0.1-2 weight portions flores aurantii, 0.01-0.2 weight portions borneol and 1-5 weight portion 4- methoxysalicylic acid potassium.
Preferably, fragrant and borneol the weight ratio of the flores aurantii is 10:1.The present invention is dissolved in flores aurantii perfume by by borneol, orange The fragrance of a flower and borneol primarily serve the fragrance for improving Chinese medicine Whitening, spot breast of the present invention.
The methoxysalicylic acid potassium, also known as 4MSK, are medicinal whitening compositions, with the generation for suppressing melanin, are prevented The color spot generated by Exposure to Sunlight, the effect of freckle.4MSK not only has the effect for suppressing melanin generation, can more adjust angling mistake The situation of Cheng Bushun.Compounded with Chinese medicine compound prescription of the invention, it is possible to increase the efficiency that comes into force of Chinese medicine Whitening, spot breast of the present invention, soon Speed removes color spot.
A kind of preparation method of Chinese medicine Whitening, spot breast as described above, comprises the following steps:(1)By thickener, polynary 70-90 DEG C is heated to after the mixing of alcohol, hyaluronic acid and water, homogeneous 5min is incubated 30-60min, obtains A and mixes liquid;(2)Will 70-90 DEG C is heated to after emulsifying agent and base oil mixing, then under conditions of stirring, preservative, stirring homogeneous 5- is added 15min, obtains B and mixes liquid;(3)A is mixed into liquid and is cooled to 35-55 DEG C, in mixing liquid toward A add B mix liquid and Other raw materials, vacuumize, stirring homogeneous 5-15min, you can filtering and discharging, and the Chinese medicine Whitening, spot breast is obtained.
If other raw materials include that flores aurantii perfume and borneol, the borneol are used in being previously dissolved in flores aurantii perfume;If including 4MSK, 4MSK are used in being previously dissolved in part water, it is preferable that the 4MSK is 1 with the weight ratio of the part water:1.
It is further preferable that the Chinese medicine Whitening, spot breast is made up of the raw material of following percentage by weight:
Camellia oil 10%
Shea butter 5%
SS 1%
SSE20 1.5%
Lecithin 3%
Polyacrylate cross-linked polymer -6 0.3%
Glycerine 5%
Butanediol 10%
Hyaluronic acid 0.03%
Sensiva SC50 0.1%
Phenoxyethanol 0.5%
Chinese medicine extract A 20%
Chinese medicine extract B 5%
Water 34.47%
Flores aurantii perfume (or spice) 1%
Borneol 0.1%
4MSK 3%;
Every 10 weight portion Chinese medicine extract A prepares prepared by the following method:Take levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, river Rhizome of chuanxiong, corydalis tuber, the Radix Astragali and each 1.25 weight portion of Radix Glycyrrhizae, are added in 50 weight portion water, are concentrated by boiling cold filtration, obtain 10 described weight portion Chinese medicine extract A.
Beneficial effects of the present invention:1st, Chinese medicine Whitening, spot of the invention breast using levisticum, schizonepeta, windproof and radix bupleuri in Medicine compound, can play the damp and hot effect of removal epidermis, color spot be removed from root, and reduce recurrence possibility;2nd, this hair Bright Chinese medicine Whitening, spot breast, in addition to it can effectively effect a radical cure color spot problem, moreover it is possible to anti-inflammatory Shu Min, solves most of women mistakes at present The allergic problem that degree is brought using skin care item;3rd, Sodium Hyaluronate has very powerful water holding, water lock ability, is prevalent in In intercellular matrix, in human body skin skin corium content at most, with skin moisture content is kept, make skin smooth and be rich in bullet Property effect, strengthen Chinese medicine compound prescription eliminating toxic dampness and heat effect.
Specific embodiment
The invention will be further described with the following Examples.
Embodiment 1
A kind of Chinese medicine Whitening, spot breast, including following parts by weight raw material:
15 parts of base oil
5.5 parts of emulsifying agent
0.3 part of thickener
15 parts of polyalcohols NMF
0.03 part of hyaluronic acid
0.6 part of preservative
20 parts of Chinese medicine extract A
5 parts of Chinese medicine extract B
31.47 parts of water
The base oil is shea butter, and the emulsifying agent is lecithin, and the thickener is Carbomer, and the polyalcohols are protected Humectant is butanediol, and the preservative is Phenoxyethanol;The Chinese medicine extract A is obtained by Chinese medicine is extracted, the Chinese medicine package Levisticum, schizonepeta, windproof and radix bupleuri are included, the 10 weight portion Chinese medicine extract A is extracted by decocting by 22.5 weight portion Chinese medicines and made ;The Chinese medicine extract B is dissolved in food grade ethanol and is obtained by 0.3 weight portion dragon's blood.
Embodiment 2
The present embodiment is with the difference of embodiment 1:
The base oil is by camellia oil and shea butter by weight 2:1 ratio composition;The emulsifying agent is by lecithin, methyl Glucoside sesquistearate-EO-20 and methyl glucoside sesquistearate are by weight 3:1.5:1 ratio group Into;The polyalcohols NMF is by glycerine and butanediol by weight 1:2 ratio composition;The thickener is polyacrylic acid Ester cross-linked polymer -6;The preservative is by Sensiva SC50 and Phenoxyethanol in mass ratio 1:5 ratio composition.
Embodiment 3
The present embodiment is with the difference of embodiment 2:
The 10 weight portion Chinese medicine extract A prepares prepared by the following method:Take levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, river Rhizome of chuanxiong, corydalis tuber, the Radix Astragali and each 1.25 weight portion of Radix Glycyrrhizae, are added in 50 weight portion water, are concentrated by boiling cold filtration, obtain 10 described weight portion Chinese medicine extract A.
Embodiment 4
The present embodiment is with the difference of embodiment 3:
Also include fragrant 5 weight portion Chinese medicine extract B, 1 weight portion flores aurantii, 0.1 weight portion borneol and 3 weight portion 4- methoxysalicylics Sour potassium;The parts by weight of the water are 34.47 parts.
Embodiment 5
A kind of Chinese medicine Whitening, spot breast, including following parts by weight raw material:
10 parts of base oil
4 parts of emulsifying agent
0.1 part of thickener
10 parts of polyalcohols NMF
0.01 part of hyaluronic acid
0.3 part of preservative
15 parts of Chinese medicine extract A
4 parts of Chinese medicine extract B
30 parts of water
Flores aurantii is fragrant 0.1 part
0.01 part of borneol
1 part of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, Ligusticum wallichii, Corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is:Each Chinese medicine weighs the addition of 1 weight portion To in 50 weight portion water, cold filtration concentration is boiled, obtain the 10 weight portion Chinese medicine extract A;The Chinese medicine extract B by 0.1 weight portion dragon's blood is dissolved in food grade ethanol and is obtained;
The base oil is made up of 7 weight portion camellia oils and 3 weight portion shea butters, and the emulsifying agent is by 2.5 weight portion lecithins Fat, 1 weight portion methyl glucoside sesquistearate-EO-2,0.5 weight portion methyl glucoside sesquistearate group Into the thickener is polyacrylate cross-linked polymer -6, and the polyalcohols NMF is by 2.5 parts by weight of glycerin and 7.5 Weight portion butanediol is constituted, and the preservative is made up of 0.05 weight portion Sensiva SC50 and 0.25 weight portion Phenoxyethanol.
Embodiment 6
A kind of Chinese medicine Whitening, spot breast, including following parts by weight raw material:
20 parts of base oil
7 parts of emulsifying agent
0.5 part of thickener
20 parts of polyalcohols NMF
0.05 part of hyaluronic acid
0.9 part of preservative
25 parts of Chinese medicine extract A
6 parts of Chinese medicine extract B
60 parts of water
Flores aurantii is fragrant 2 parts
0.2 part of borneol
5 parts of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, Ligusticum wallichii, Corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is:Each Chinese medicine weighs the addition of 4 weight portions To in 50 weight portion water, cold filtration concentration is boiled, obtain the 10 weight portion Chinese medicine extract A;The Chinese medicine extract B by 0.5 weight portion dragon's blood is dissolved in food grade ethanol and is obtained.
The base oil is made up of 6 weight portion camellia oils and 4 weight portion shea butters, and the emulsifying agent is by 3.5 weight portions Lecithin, 2 weight portion methyl glucoside sesquistearate-EO-2,1.5 weight portion methyl glucoside sesquistearates Composition, the thickener is polyacrylate cross-linked polymer -6, the polyalcohols NMF by 7.5 parts by weight of glycerin and 12.5 weight portion butanediols are constituted, and the preservative is by 0.15 weight portion Sensiva SC50 and 0.75 weight portion Phenoxyethanol group Into.
Embodiment 7
A kind of Chinese medicine Whitening, spot breast, including following parts by weight raw material:
12 parts of base oil
5 parts of emulsifying agent
0.2 part of thickener
13 parts of polyalcohols NMF
0.02 part of hyaluronic acid
0.5 part of preservative
17 parts of Chinese medicine extract A
4.5 parts of Chinese medicine extract B
40 parts of water
Flores aurantii is fragrant 0.3 part
0.03 part of borneol
2 parts of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, Ligusticum wallichii, Corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is:Each Chinese medicine weighs the addition of 2 weight portions To in 50 weight portion water, cold filtration concentration is boiled, obtain the 10 weight portion Chinese medicine extract A;The Chinese medicine extract B by 0.2 weight portion dragon's blood is dissolved in food grade ethanol and is obtained.
The base oil is made up of 8 weight portion camellia oils and 4 weight portion shea butters, and the emulsifying agent is by 2.5 weight portions Lecithin, 2 weight portion methyl glucoside sesquistearate-EO-2,0.5 weight portion methyl glucoside sesquistearate Composition, the thickener is polyacrylate cross-linked polymer -6, and the polyalcohols NMF is by 7 parts by weight of glycerin and 6 weights Amount part butanediol composition, the preservative is made up of 0.05 weight portion Sensiva SC50 and 0.45 weight portion Phenoxyethanol.
Embodiment 8
A kind of Chinese medicine Whitening, spot breast, including following parts by weight raw material:
17 parts of base oil
5 parts of emulsifying agent
0.4 part of thickener
17 parts of polyalcohols NMF
0.04 part of hyaluronic acid
0.8 part of preservative
23 parts of Chinese medicine extract A
6 parts of Chinese medicine extract B
55 parts of water
Flores aurantii is fragrant 1.5 parts
0.15 part of borneol
4 parts of 4- methoxysalicylic acids potassium
The Chinese medicine extract A is obtained by traditional Chinese medicine extraction, the Chinese medicine include levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, Ligusticum wallichii, Corydalis tuber, the Radix Astragali and Radix Glycyrrhizae.The preparation method of every 10 weight portion Chinese medicine extract A is:Each Chinese medicine weighs the addition of 3 weight portions To in 50 weight portion water, cold filtration concentration is boiled, obtain the 10 weight portion Chinese medicine extract A;The Chinese medicine extract B by 0.4 weight portion dragon's blood is dissolved in food grade ethanol and is obtained.
The base oil is made up of 12 weight portion camellia oils and 5 weight portion shea butters, and the emulsifying agent is by 3.5 weight portions Lecithin, 1 weight portion methyl glucoside sesquistearate-EO-2,0.5 weight portion methyl glucoside sesquistearate Composition, the thickener is polyacrylate cross-linked polymer -6, and the polyalcohols NMF is by 11 parts by weight of glycerin and 6 weights Amount part butanediol composition, the preservative is made up of 0.1 weight portion Sensiva SC50 and 0.7 weight portion Phenoxyethanol.
Carrying out whitening effect test to the Chinese medicine Whitening, spot breast of embodiment 1-8 respectively, it is 20 at the age that experimental subjects is~ 35 years old, there is the women 90 of color spot or other speckles on the face, be arbitrarily divided into 10 Yuans one group, altogether 8 experimental groups and 1 control Group;Experimental technique applies face using Chinese medicine Whitening, spot breast every night for the women of experimental group, and control group women uses tradition every night Tartaric acid cleawhite pack applies face, and usage cycles are 30 days, and skin was checked to those dermal melanin testers for women every 10 days Middle melanin content, and the average value of melanin inhibiting rate is calculated according to the following formula --- melanin inhibiting rate=(Control group skin Skin melanin content-experimental group dermal melanin content)/ control group dermal melanin content * 100%.Obtain the experiment knot of following table Really.
By the observation of 30 days, Chinese medicine Whitening, spot breast of the invention had obvious effect to color spot, and skin colourity is obtained It is obvious to decline.This explanation Whitening, spot breast of the invention further promotes the angle containing melanocyte in addition to suppressing the synthesis of melanin Cell plastid comes off, or is restricted the melanocyte Melanogenic ability of product, so as to reach skin whitening effect.
Finally it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than the present invention is protected The limitation of scope is protected, although being explained to the present invention with reference to preferred embodiment, one of ordinary skill in the art should Work as understanding, technical scheme can be modified or equivalent, without deviating from the reality of technical solution of the present invention Matter and scope.

Claims (10)

1. a kind of Chinese medicine Whitening, spot is newborn, it is characterised in that:The raw material of the Chinese medicine Whitening, spot breast including following parts by weight:
Base oil 10-20 parts
Emulsifying agent 4-7 parts
Thickener 0.1-0.5 parts
10-20 parts of polyalcohols NMF
Hyaluronic acid 0.01-0.05 parts
Preservative 0.3-0.9 parts
15-25 parts of Chinese medicine extract A
4-6 parts of Chinese medicine extract B
Water 30-60 parts
The Chinese medicine extract A by Chinese medicine through decocting extract be obtained, the Chinese medicine include levisticum, schizonepeta, windproof, radix bupleuri, Radix Angelicae Sinensis, Ligusticum wallichii, corydalis tuber, the Radix Astragali and Radix Glycyrrhizae, the thickener are polyacrylate cross-linked polymeric species thickener.
2. a kind of Chinese medicine Whitening, spot according to claim 1 is newborn, it is characterised in that:Original including following parts by weight Material:
15 parts of base oil
5.5 parts of emulsifying agent
0.3 part of thickener
15 parts of polyalcohols NMF
0.03 part of hyaluronic acid
0.6 part of preservative
20 parts of Chinese medicine extract A
5 parts of Chinese medicine extract B
31.47 parts of water.
3. a kind of Chinese medicine Whitening, spot according to claim 1 is newborn, it is characterised in that:The Chinese medicine extract B is dragon's blood Alcohol extract.
4. a kind of Chinese medicine Whitening, spot according to claim 1 or 3 is newborn, it is characterised in that:Every 10 weight portion traditional Chinese medicine extraction Liquid A is extracted by decocting by 9-36 weight portions Chinese medicine and is obtained.
5. a kind of Chinese medicine Whitening, spot according to claim 1-3 any one is newborn, it is characterised in that:The base oil by 7-13 weight portions camellia oil and 3-7 weight portions shea butter are constituted.
6. a kind of Chinese medicine Whitening, spot according to claim 1-3 any one is newborn, it is characterised in that:The emulsifying agent by 2.5-3.5 weight portions lecithin, 1-2 weight portion methyl glucoside sesquistearate-EO-20 and 0.5-1.5 weight portion first Base glucoside sesquistearate is constituted.
7. a kind of Chinese medicine Whitening, spot according to claim 1-3 any one is newborn, it is characterised in that:The polyalcohols NMF is made up of 2.5-7.5 parts by weight of glycerin and 7.5-12.5 weight portion butanediols.
8. a kind of Chinese medicine Whitening, spot according to claim 1-3 any one is newborn, it is characterised in that:The preservative by 0.05-0.15 weight portions Sensiva SC50 and 0.25-0.75 weight portions Phenoxyethanol are constituted.
9. a kind of Chinese medicine Whitening, spot according to claim 1-3 any one is newborn, it is characterised in that:The Chinese medicine whitening Light spot breast also includes fragrant 0.1-2 weight portions flores aurantii, 0.01-0.2 weight portions borneol and 1-5 weight portion 4- methoxysalicylic acid potassium.
10. a kind of newborn preparation method of Chinese medicine Whitening, spot as described in claim any one of 1-9, it is characterised in that:Including Following steps:(1)70-90 DEG C is heated to after thickener, polyalcohol, hyaluronic acid and water are mixed, homogeneous 5min is incubated 30- 60min, obtains A and mixes liquid;(2)70-90 DEG C is heated to after emulsifying agent and base oil are mixed, then in the condition of stirring Under, preservative is added, homogeneous 5-15min is stirred, obtain B and mix liquid;(3)A is mixed into liquid and is cooled to 35-55 DEG C, toward A phases Add B to mix liquid and other raw materials in mixed liquor, vacuumize, stirring homogeneous 5-15min, you can filtering and discharging is obtained described Chinese medicine Whitening, spot breast.
CN201710114804.8A 2017-02-28 2017-02-28 A kind of Chinese medicine Whitening, spot breast and preparation method thereof Pending CN106890120A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110037972A (en) * 2019-05-14 2019-07-23 广州法蒂芙生物科技有限公司 A kind of Whitening, spot stoste and its compounding method
CN111714390A (en) * 2019-03-19 2020-09-29 西安博鸿生物技术有限公司 Whitening essence milk and preparation method thereof
CN111743826A (en) * 2019-03-29 2020-10-09 和和有限公司 Freckle-removing, wrinkle-resisting and moisturizing emulsion

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1448161A (en) * 2002-03-30 2003-10-15 张善领 Process formula of skin-care liquid
CN105125651A (en) * 2015-09-06 2015-12-09 河南科技大学 Whitening and freckle-lightening composition and preparation method and application method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1448161A (en) * 2002-03-30 2003-10-15 张善领 Process formula of skin-care liquid
CN105125651A (en) * 2015-09-06 2015-12-09 河南科技大学 Whitening and freckle-lightening composition and preparation method and application method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111714390A (en) * 2019-03-19 2020-09-29 西安博鸿生物技术有限公司 Whitening essence milk and preparation method thereof
CN111743826A (en) * 2019-03-29 2020-10-09 和和有限公司 Freckle-removing, wrinkle-resisting and moisturizing emulsion
CN110037972A (en) * 2019-05-14 2019-07-23 广州法蒂芙生物科技有限公司 A kind of Whitening, spot stoste and its compounding method

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Application publication date: 20170627