CN106511211A - Anti-inflammatory and anti-acne skin care lotion and preparation method thereof - Google Patents

Anti-inflammatory and anti-acne skin care lotion and preparation method thereof Download PDF

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Publication number
CN106511211A
CN106511211A CN201611174498.9A CN201611174498A CN106511211A CN 106511211 A CN106511211 A CN 106511211A CN 201611174498 A CN201611174498 A CN 201611174498A CN 106511211 A CN106511211 A CN 106511211A
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filtrate
water
weight
extracts
filters
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CN106511211B (en
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孙淑萍
王亚娟
胡小沣
吴云
汤大娟
池翠萍
郭派派
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Guangzhou Chenlong Biotechnology Co ltd
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Wannan Medical College
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/22Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
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    • A61K8/37Esters of carboxylic acids
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    • A61K8/73Polysaccharides
    • A61K8/733Alginic acid; Salts thereof
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    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

The invention discloses an anti-inflammatory and anti-acne skin care lotion and a preparation method thereof. The lotion contains the following substances including sea buckthorn fruit oil, hazelnut oil, Argan oil, mango butter, honeysuckle flower extract liquid, coix seed extract liquid, radix paeoniae alba extract liquid, fructus forsythia extract liquid, liquorice extract liquid, red flower extract liquid, caulis spatholobi extract liquid, white poria extract liquid, leonurus extract liquid, sodium alginate tech grade, Carbomer 941, a compound emulsifier AC-402, distilled water and essences. Compared with the prior art, the lotion not only can remove acnes on the outer portion of the epidermis, but also can diminish inflammation and fade acne marks, and emphasizes nursing of the internal secretion of patients. The traditional Chinese medicine essences act on acnes, the acnes absorb the medicine slowly during metabolism and then are removed naturally, and the patients are cured. Meanwhile, the anti-inflammatory and anti-acne skin care lotion can also play a good role in nourishing the skin.

Description

A kind of antiinflammatory anti-acne facial treatment milk and preparation method thereof
Technical field
The present invention relates to a kind of emulsion, more particularly to a kind of antiinflammatory anti-acne facial treatment milk and preparation method thereof.
Background technology
Acne is a kind of chronic inflammatory skin of pilosebaceous unit, is mainly apt to occur in teenager, to teenager Psychology and social influence it is very big.Clinical manifestation to be apt to occur in the acne of face, pimple, pustule, the pleomorphism skin lesion such as tuberosity is Feature, have another name called acne, comedo.The generation of acne is mainly blocked with hypersteatosiss, pilosebaceous duct, bacterium infection It is closely related with the factor such as inflammatory reaction.The androgen in descendant's body that adolesces is particularly the level of testosterone and raises rapidly, promotees Enter sebaceous gland to develop and produce a large amount of sebums.The dyskeratosis of pilosebaceous duct causes catheter blockage, sebum to discharge simultaneously Obstacle, it is micropowder thorn to form horn plug.Multiple-microorganism especially propionibacterium acness amount reproduction, acne propanoic acid bar in hair follicle The lipase that bacterium produces decomposes sebum and generates free fatty, while chemotactic inflammatory cell and medium, finally induce and increase inflammation Reaction.
The method for the treatment of acne has at present:Oral antibiotic/vitamin/glucocorticoid/gonadal hormone zinc preparation and external Drug therapy, the therapy such as injection treatment/laser ultraviolet in skin lesion.Although these methods also have certain effect, have The side effect such as certain the drawbacks of, such as endo-medicine overlong time, antibiotic/hormone, injection treatment/laser ultraviolet in skin lesion Compare pain etc. therapy, laser therapy easily forms the charring layer of black, disturb surgical field of view, make patient be difficult observation and grasp treatment The depth for being reached.If being difficult to control the result for the treatment of if over the course for the treatment of, assurance is not in place.
For this phenomenon we in addition to hospital can be gone to use the Therapeutic Method such as medicine/laser, contained using some The emulsion of Chinese medicine natural constituent extracting solution also has good therapeutic effect, so as to develop the emulsion of the present invention.
The content of the invention
In order to solve problems of the prior art, the present invention provides a kind of new containing natural Chinese medicine constituents extraction liquid Antiinflammatory anti-acne facial treatment milk.
The present invention is employed the following technical solutions:
A kind of antiinflammatory anti-acne facial treatment milk, comprising following material:
Preferably, described Flos Lonicerae extractive solution is prepared by the following method:
Flos Lonicerae 50-100g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 15-20 times Flos Lonicerae weights The water of amount, extracts 1.0-2h, filters to get filtrate the 1, the 2nd time and adds the water of 10-15 times of Flos Lonicerae weight, extract 0.5-1.5h, filters Filtrate 2, the water of the 3rd time plus 8-15 times of Flos Lonicerae weight extracts 0.5-1.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, It is 3-6 times of Flos Lonicerae weight (g) that heating is concentrated into the volume (ml) of filtrate, filters and obtains final product Flos Lonicerae extractive solution.
Preferably, described Semen Coiciss extracting solution is prepared by the following method:
Semen Coiciss 100-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 15-25 times of Semen Coiciss The water of weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 10-15 times of Semen Coiciss weight, extract 0.5-1.5h, filters Filtrate 2, the water of the 3rd time plus 8-9 times of Semen Coiciss weight extracts 0.5-1.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, It is 3-6 times of Semen Coiciss weight (g) that heating is concentrated into the volume (ml) of filtrate, filters and obtains final product Semen Coiciss extracting solution.
Preferably, described white paeony root extract is prepared by the following method:
Radix Paeoniae Alba coarse powder 100-200g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus the 20-25 times of Radix Paeoniae Alba The water of weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 15-20 times of Radix Paeoniae Alba weight, extracts 0.5-1.5h, filter Filtrate 2, the water of the 3rd time plus 8-15 times of Radix Paeoniae Alba weight extract 0.5-1.5h, filter to get filtrate 3, filtrate 1,2,3 are merged, heating The volume (ml) for being concentrated into filtrate is 2-5 times of Radix Paeoniae Alba weight (g), filters and obtains final product white paeony root extract.
Preferably, described YINQIAO extracting solution is prepared by the following method:
Fructus Forsythiae coarse powder 100-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 15-20 times of Fructus Forsythiae The water of weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 12-16 times of Fructus Forsythiae weight, extracts 0.5-1.5h, filter Filtrate 2, the water of the 3rd time plus 8-12 times of Fructus Forsythiae weight extract 0.5-1.5h, filter to get filtrate 3, filtrate 1,2,3 are merged, heating The volume (ml) for being concentrated into filtrate is 3-6 times of Fructus Forsythiae weight (g), filters and obtains final product Fructus Forsythiae extracting solution.
Preferably, described Radix Glycyrrhizae extract is prepared by the following method:
Radix Glycyrrhizae coarse powder 100-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-30 times of Radix Glycyrrhizae The water of weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 15-20 times of Radix Glycyrrhizae weight, extracts 0.5-1.5h, filter Filtrate 2, the water of the 3rd time plus 8-15 times of Radix Glycyrrhizae weight extract 0.5-1.5h, filter to get filtrate 3, filtrate 1,2,3 are merged, heating The volume (ml) for being concentrated into filtrate is 3-6 times of Radix Glycyrrhizae weight (g), filters and obtains final product Radix Glycyrrhizae extract.
Preferably, described Flos Carthami extract is prepared by the following method:
Flos Carthami 100-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-25 times of Flos Carthami weight Water, extract 1-2h, the water of filter to get filtrate the 1, the 2nd time plus 15-20 times of Flos Carthami weight extracts 0.5-1.5h, filters to get filtrate The water of the 2, the 3rd time plus 8-15 times of Flos Carthami weight, extracts 0.5-1.5h, filters to get filtrate 3, filtrate 1,2,3 is merged, heating concentration Volume (ml) to filtrate is 3-6 times of Flos Carthami weight (g), filters and obtains final product Flos Carthami extract.
Preferably, described Herba Leonuri extracting solution is prepared by the following method:
Herba Leonuri coarse powder 90-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-25 times of Herba Leonuri The water of careless weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 15-20 times of Herba Leonuri weight, extracts 0.5-1.5h, mistake Filter to obtain filtrate 2, the water of the 3rd time plus 8-15 times of Herba Leonuri weight extracts 0.5-1.5h, filter to get filtrate 3, filtrate 1,2,3 is closed And, it is 3-6 times of Herba Leonuri weight (g) that heating is concentrated into the volume (ml) of filtrate, filters and obtains final product Herba Leonuri extracting solution.
Preferably, described Poria extracting solution is prepared by the following method:
Poria coarse powder 100-150g is weighed, 0.5-0.8h after crushing, is soaked, heating is decocted extracts 3 times, the 1st time plus 18- The water of 24 times of Poria weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 13-18 times of Poria weight, extracts 0.5- 1.5h, the water of filter to get filtrate the 2, the 3rd time plus 8-13 times of Poria weight extract 0.5-1.5h, filter to get filtrate 3, by filtrate 1st, 2,3 merge, and it is 3-6 times of Poria weight (g) that heating is concentrated into the volume (ml) of filtrate, filters and obtains final product Poria extraction Liquid.
Preferably, described Caulis Spatholobi extracting solution is prepared by the following method:
Caulis Spatholobi coarse powder 100-120g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-25 times of chicken The water of Caulis seu Radix Schisandrae Henryi weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 16-20 times of Caulis Spatholobi weight, extracts 0.5-1.5h, The water of the 2, the 3rd time plus the 8-16 times of Caulis Spatholobi weight of filtering to get filtrate, extracts 0.5-1.5h, filters to get filtrate 3, by filtrate 1,2,3 Merge, it is 3-6 times of Caulis Spatholobi weight (g) that heating is concentrated into the volume (ml) of filtrate, filters and obtains final product Caulis Spatholobi extracting solution.
Preferably, described essence selected from rose essence, Fructus Citri Limoniae essence, Bulbus Lilii essence, peach flavor, osmanthus flower fragrance, One or more in green cucumber essence.
Preferably, described coarse powder all can be sieved by No. two, wherein being mixed with the powder that can pass through No. four sieves less than 40% End.
Preferably, 75% described ethanol refers to the ethanol solution that volume fraction is 75%.
A kind of preparation method of antiinflammatory anti-acne facial treatment milk, comprises the following steps:
A) take a clean beaker and weigh Oleum Hippophae 0.5-1g, hazelnut oil 0.2-1g, mango butter 0.5-1g, Ah glycerol 0.2- 1g, and compound emulsifying agent AC-4021-3g is added in this beaker, heating in water bath on 70-90 DEG C of water-bath is put, as oil phase;
B) 10-20ml distilled water is measured, heating in water bath on 70-90 DEG C of water-bath is put, as water phase;
C) treat that oil phase is identical with water phase temperature, water is mutually added in oil phase in thread shape, it is stirring while adding until being formed Uniform emulsion basess 1;
D) Flos Lonicerae extractive solution 1-8g, Semen Coiciss extracting solution 1-15g, Herba Leonuri extracting solution 0.5-5g, Fructus Forsythiae are weighed respectively Extracting solution 1-7g, Poria extracting solution 1-7g, Radix Glycyrrhizae extract 0.5-5g, white paeony root extract 0.5-5g, Caulis Spatholobi extracting solution 1- 8g, Flos Carthami extract 1-8g, mix homogeneously, as solution 1;
E) 0.1-1g sodium alginates are weighed, is dispensed in 20-50ml distilled water, form coagulant liquid 1;
F) 0.1-1g Carbopol 941s are weighed, is dispensed in 20-50ml distilled water, form coagulant liquid 2;
G) ethyl hydroxybenzoate 0.16-0.36g is weighed, is dissolved in adding the ethanol that 1-3ml volume fractions are 75%, form anti- Rotten agent solution;
H) solution 1, coagulant liquid 1, coagulant liquid 2, antiseptic solution, essence 0.05-0.25ml are separately added into into emulsion basess 1 In, it is thoroughly mixed uniformly, obtains final product antiinflammatory anti-acne facial treatment milk.
The effect of the various composition in the present invention is as follows:
Flos Lonicerae heat-clearing and toxic substances removing, enhancing immunity, antiinflammatory, qi-restoratives treat wind, cure mainly warm disease heating, toxic-heat and blood stasis, carbuncle furuncle Skin ulcer, skin infection, erysipelas, parotitiss, suppurative tonsillitiss etc..Procyanidin that Flos Lonicerae contains, double pyrite, polyphenol, plant The various active factors such as fibres element, polypeptide, short-chain fatty acid.These compositions physiological action special for women has, be The fracture of human body Elastic tissue, collagen fiber and fibroblast and the important substance being lost in are safeguarded and prevent, with rapid osmotic Enter skin, mutual induction between active cell, the facial microcirculation of dredging, the function of reformation skin structure of fibrous tissue.By reducing Free radical damage, repair and filling subside, make skin obtain it is similar to original structure pile up, recovery skin compactness, so as to Reach and unfold coarse groove, desalinate microgroove, kept for the appearance youth not old.《Compendium of Materia Medica》Record Flos Lonicerae treatment:All rheumatism gas, and All toxic swellings, carbuncle scabies, all malignant boil of Fructus Myricae rubrae.
Herba Leonuri promoting tissue regeneration by removing blood stasis, promoting blood flow to regulate menstruation, reducing swelling and alleviating pain also can be used for itchy skin eruption.Chang Yinke blood circulation promoting and blood stasis dispelling, strengthens Endocrine function and skin immunization power, slow down skin aging.If grinding Herba Leonuri and spreading on face, face's oil can be effectively removed Fat, sterilizing, glabrous skin, have certain effect to treating skin sore.
Caulis Spatholobi replenishing and activating blood, channels sootheing and network vessel quickening.Rattan hyoscine, has Fufeng, the effectiveness of promoting blood circulation;Root is used as medicine, the work(for having promoting blood circulation Can, also there iss parasite killing.Rattan and root contain phenolic constituent, aminoacid, saccharide, resin, can relaxing muscles and tendons to promote blood circulation, nourishing blood for regulating menstruation.
Flos Carthami acrid in the mouth, warm in nature, GUIXIN, Liver Channel.Gas perfume row dissipates, and enters blood system, with promoting blood circulation to restore menstrual flow, effect of dispelling phlegm and alleviating pain. In terms of beauty, Flos Carthami can be with balancing hormones, regulation of mental activities pneumostatic, eliminating toxin and beautifying the skin, freckle removing and whitening.Flos Carthami adjusts people while speckle dispelling Secrete in vivo, accelerate human metabolism, exclude vivotoxin, be that a best environment is created in speckle dispelling and neoblast regeneration; Cucumber Extract, supplements skin vigour simultaneously, improves skin horn cell water storage, the ability shunk, lifts corneocyte aqueous Amount, makes horny layer enter to turn to " the moistening thoroughly horn cell " of high transparency.
Semen Coiciss can promote the metabolism of internal blood and moisture, whitening to moisten.Its main component is protein, dimension life Plain B1、B2, long-term drink can make skin smooth, reduce wrinkle, eliminate effect of pigment spot, can treat brown while whitening Speckle, freckle, pimples, make speckle disappear and Glycerin, also can reach sun-proof and anti-ultraviolet effect.Semen Coiciss have in itself Moist skin, whitening mend it is wet, the effects such as promoting flow of QI and blood pain relieving.
Poria eliminating dampness and diuresises, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Poria energy dispelling speckles and whitening face, moist skin, can also strengthen Immunologic function, expansion of blood vessels.《Bencao Pinhui Jingyao》Carry:" Poria is end, closes honey and acne vulgaris and the black bleb of puerpera are treated in surface application Such as Ovum passeris.”
Radix Paeoniae Alba blood-nourishing yin fluid astringing, easing the affected liver to relieve pain, Pinggan Yang.In theory of Chinese medical science, the Radix Paeoniae Alba plays the role of nourishing blood to suppress the hyperactive liver, and " liver It is strongly fragrant " it is to cause the colour of skin dim heavy and the reason for mottle, free radical, antioxidative effect are also removed, treatment complexion is generally used for and is withered The symptoms such as Huang, facial colour spot, melanin deposition thing, tarnish, from inside to outside carry out conditioning skin whitening.
Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the title for having " persons particularly liable to develop skin infection's panacea ".Control warm, erysipelas, macule, large carbuncle pyogenic infections.Fructus Forsythiae Antimicrobial spectrum is very wide, has obvious antiinflammatory action, can promote the formation of inflammatory barrier, reduces capillary permeability, reduces inflammatory Ooze out, eliminate the local redness that comedo causes.There is certain inhibitory action to smegma, reduce skin excess oiliness, Oily skin is had functions that to improve skin quality.Fructus Forsythiae can protect normal skin, reduce the generation of comedo and folliculitises.
Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.It is raw with curing mainly cellulitis skin infection, and solve poison of drug, Alimentary toxicosis etc..Radix Glycyrrhizae has the function of antiinflammatory and antiallergic action.
Radix Glycyrrhizae also has effect of beauty.Its composition can suppress the activity of tryrosinase, reduce melanic generation.It is also With anti-oxidation function, prevent skin aging from blacking.
Ah's glycerol contains more Vitamin E and rare plant sterol, and polyphenolic substance can help softening skin, thorn Sharp pore toxin expelling, can resist wrinkle to free radical resisting, and delay skin aging can promote skin metabolism, reduce pigment and sink Product, Bergamot Mint Extract make skin keep drying pure and fresh, repair because sunlight or pressure cause impaired skin;Effectively water lock is protected It is wet, keep skin moist full, skin is allowed away from coarse and dry;The rapid skin care of energy, helps horn cell regeneration, prevention And skin cicatrix is repaired, and promote which newborn;Can effective dredging pore, keep sebum normal secretions, eliminate skin sore and help is hindered Mouth healing.
Oleum Hippophae contains carotenoid, flavonoid and Vitamin E, vitamin A, and various trace elements, such as selenium, Magnesium, zinc, ferrum, manganese etc..Oleum Hippophae can promote facial microvascular circulation, can effectively remove facial colour spot, wrinkle, acne, Play the many-side effect such as moist, whitening, speckle dispelling, smoothing wrinkle;The work of also certain radiation resistance and preventing and treating scald and cold injury With reduction infection.
Hazelnut oil contains mineral, vitamin A, B and E, and good penetrability will not leave greasy dirt in skin surface.It has soft Change the effect moistened, help the regeneration of skin, effectively prevent aging, with convergence, blending property, can quickly be absorbed, be reconciled Skin tightening, helps skin to keep stable and elasticity;The perverse base oil of oily skin, mixed skin and conditioning powder can be made;By force Change blood capillary, stimulate cell regeneration.
Mango butter contains higher non-saponifiable matter, with natural soft Compliant Force, high oxidation power, promote wound healing with And skin regeneration, skin-moisturizing, skin, skin hydration effect is maintained, lubricates skin emolliency, regenerated and antioxidation, prevent skin from shifting to an earlier date It is aging;Skin can be pacified with softness, moisturizing strengthens skin resistance, reinvents skin elasticity and cell viability, moreover it is possible to effectively Resist ultraviolet.
Carbopol 941 is excellent gel-type vehicle, has thickening effect, good stability, extensively using emulsion, cream, gel In, for skin surface, smear is good, without greasy feeling, does not pollute clothes, and ventilative, infiltration rate is fast.
Sodium alginate is a kind of natural polysaccharide, may generally serve as emulsion stabilizer and thickening agent.Hydrophilic is strong, in cold water and Can dissolve in warm water, form very sticky uniform solution;There are the true solution of formation other analog to be difficult to what is obtained Flexibility, homogeneity, the effect with very strong protecting colloid.
Essence can remove the unhappy abnormal smells from the patient in original product with having sedation and excitation in the product to people, Unique essence abnormal smells from the patient can more attract consumer, some essence to have antibacterial, anti-corrosion, mildew-proof function.
The device have the advantages that being:Flos Lonicerae heat-clearing and toxic substances removing, antiinflammatory;Herba Leonuri promoting tissue regeneration by removing blood stasis, sterilizing, Can be used for itchy skin eruption;Caulis Spatholobi replenishing and activating blood;Flos Carthami is invigorated blood circulation, freckle removing and whitening;Semen Coiciss whitening, moist skin, promoting blood circulation and stopping pain; Poria dispelling speckles and whitening face, moist skin, treat acne vulgaris;Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver, treatment shallow complexion, facial colour spot, melanin deposition Thing, tarnish;Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds have obvious antiinflammatory action, eliminate the local redness that comedo causes;It is sweet Careless heat-clearing and toxic substances removing, skin whitening, the function of having antiinflammatory and antiallergic action;The rapid skin care of Ah's glycerol energy, helps cutin thin Born of the same parents regenerate, and prevent and repair skin cicatrix, and promote which newborn, eliminate skin sore and help wound healing;Oleum Hippophae can be effective Ground removes facial colour spot, wrinkle, acne, plays the many-side effect such as moist, whitening, speckle dispelling, smoothing wrinkle.Each composition complements each other, The effect of antiinflammatory anti-acne skin protection is played altogether.
Traditional Chinese medicine essence of the present invention acts on the sick cell in acne.Sick cell is slowly inhaled in metabolic processes Medicine is received, is then disappeared naturally flat and is come off, and stimulate teleneuron, by reflection, expansion of blood vessels, promote local blood to follow Ring, improves surrounding tissue nutrition.After medicine break-through skin and mucosa, body circulation is entered through blood vessel or lymphatic vessel, can also produce Systemic medication effect, thoroughly effects a radical cure acne so as to pull out old complaint.
As Chinese medicine acts on numerous, even if the patient for not having acne can also improve face skin using the present invention.So Say, both pharmacologic action of the present invention and skin-protecting function have concurrently, can bring glad tidings to more patients with acne.
Specific embodiment
With reference to embodiment, the present invention will be further described.
Embodiment 1
Flos Lonicerae 50g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 20 times of Flos Lonicerae weight, extracts 2h, filters to get filtrate the 1, the 2nd time and adds the water of 15 times of Flos Lonicerae weight, extract 1.5h, and filter to get filtrate the 2, the 3rd time plus 9 times of gold silver The water of flower weight, extracts 1h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is that Flos Lonicerae is heavy that heating is concentrated into the volume of filtrate 6 times of amount, filtration obtain final product Flos Lonicerae extractive solution.
Semen Coiciss coarse powder 100g is weighed, 0.8h, heating decoction extraction 3 times, the 1st time plus 25 times of Semen Coiciss weight are soaked Water, extracts 2h, filters to get filtrate the 1, the 2nd time and adds the water of 18 times of Semen Coiciss weight, extracts 1.5h, filters to get filtrate the 2, the 3rd time and adds The water of 10 times of Semen Coiciss weight, extracts 1h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate and is 5 times of Semen Coiciss weight, filtration obtain final product Semen Coiciss extracting solution.
Radix Paeoniae Alba coarse powder 200g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 22 times of Radix Paeoniae Alba weight, carries 2h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 16 times of Radix Paeoniae Alba weight, extract 1h, filter to get filtrate the 2, the 3rd time plus 9 times of Radix Paeoniae Albas weights The water of amount, extracts 1h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is the 5 of Radix Paeoniae Alba weight that heating is concentrated into the volume of filtrate Times, filtration obtains final product white paeony root extract.
Fructus Forsythiae coarse powder 100g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 23 times of Fructus Forsythiae weight, carries 2h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 13 times of Fructus Forsythiae weight, extract 1h, filter to get filtrate the 2, the 3rd time plus 9 times of Fructus Forsythiae weights The water of amount, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is the 4 of Fructus Forsythiae weight that heating is concentrated into the volume of filtrate Times, filtration obtains final product Fructus Forsythiae extracting solution.
Radix Glycyrrhizae coarse powder 100g is weighed, 0.8h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 20 times of Radix Glycyrrhizae weight, carries 2h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 15 times of Radix Glycyrrhizae weight, extract 1.5h, filter to get filtrate the 2, the 3rd time plus 10 times of Radix Glycyrrhizaes The water of weight, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is Radix Glycyrrhizae weight that heating is concentrated into the volume of filtrate 3 times, filtration obtain final product Radix Glycyrrhizae extract
Flos Carthami 100g is weighed, 0.8h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 16 times of Flos Carthami weight, extracts 2h, Filter to get filtrate the 1, the 2nd time and add the water of 10 times of Flos Carthami weight, extract 1.5h, filter to get filtrate the 2, the 3rd time and add 8 times of Flos Carthami weight Water, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate for 6 times of Flos Carthami weight, Filtration obtains final product Flos Carthami extract.
Herba Leonuri coarse powder 90g is weighed, 0.8h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 12 times of Herba Leonuri weight, 2h is extracted, is filtered to get filtrate the 1, the 2nd time and is added the water of 10 times of Herba Leonuri weight, extract 1.5h, filtered to get filtrate the 2, the 3rd time plus 8 times The water of Herba Leonuri weight, extracts 1.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is benefit that heating is concentrated into the volume of filtrate 6 times of Herba Linderniae Crustaceae weight, filtration obtain final product Herba Leonuri extracting solution.
Poria coarse powder 100g is weighed, 0.8h, heating decoction extraction 3 times, the 1st time plus 20 times of Poria weight are soaked Water, extracts 2h, filters to get filtrate the 1, the 2nd time and adds the water of 15 times of Poria weight, extracts 1.5h, filter to get filtrate the 2, the 3rd time and Jia 8 The water of times Poria weight, extracts 1.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate and is 6 times of Poria weight, filtration obtain final product Poria extracting solution.
Caulis Spatholobi coarse powder 100g is weighed, 0.8h, heating decoction extraction 3 times, the 1st time plus 25 times of Caulis Spatholobi weight are soaked Water, extracts 2h, filters to get filtrate the 1, the 2nd time and adds the water of 10 times of Caulis Spatholobi weight, extracts 1.5h, filter to get filtrate the 2, the 3rd time and Jia 8 The water of times Caulis Spatholobi weight, extracts 1.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate and is 6 times of Caulis Spatholobi weight, filtration obtain final product Caulis Spatholobi extracting solution.
Described essence is rose essence.
Described coarse powder all can be sieved by No. two, wherein be mixed with can be by the powder of No. four sieves 40%.
75% described ethanol refers to the ethanol solution that volume fraction is 75%.
A kind of preparation method of antiinflammatory anti-acne facial treatment milk, comprises the following steps:
A) take a clean beaker and weigh Oleum Hippophae 1g, hazelnut oil 1g, mango butter 1g and Ah glycerol 1g, and in this beaker Compound emulsifying agent AC-4023g is added, heating in water bath on 80 DEG C of water-baths is put, as oil phase;
B) 10ml distilled water is measured, heating in water bath on 80 DEG C of water-baths is put, as water phase;
C) treat that oil phase is identical with water phase temperature, oil phase is added in water phase in thread shape, it is stirring while adding until being formed Uniform emulsion basess 1;
D) Flos Lonicerae extractive solution 5g, Semen Coiciss extracting solution 6g, yellow white paeony root extract 6g, Fructus Forsythiae extracting solution 6g are weighed respectively, Radix Glycyrrhizae extract 6g, Herba Leonuri extracting solution 5g, Poria extracting solution 5g, Flos Carthami extract 5g, white paeony root extract 5g, Caulis Spatholobi are carried Take liquid 5g, mix homogeneously, as solution 1;
E) 0.1 sodium alginate is weighed, is dispensed in 20ml distilled water, form coagulant liquid 1;
F) 0.1g Carbopol 941s are weighed, is dispensed in 20ml distilled water, form coagulant liquid 2;
G) ethyl hydroxybenzoate 0.16g is weighed, the dissolving of 75% ethanol of 1ml is added, is formed antiseptic solution;
H) by solution 1, coagulant liquid 1, coagulant liquid 2, antiseptic solution, essence 0.1ml, in adding emulsion basess 1, fully stir Mix homogeneously is mixed, antiinflammatory anti-acne facial treatment milk is obtained final product.
Embodiment 2
Flos Lonicerae 80g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 19 times of Flos Lonicerae weight, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 12 times of Flos Lonicerae weight, extract 1h, and filter to get filtrate the 2, the 3rd time plus 9 times of gold silver The water of flower weight, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is Flos Lonicerae that heating is concentrated into the volume of filtrate 3 times of weight, filtration obtain final product Flos Lonicerae extractive solution.
Semen Coiciss coarse powder 150g is weighed, 0.5h, heating decoction extraction 3 times, the 1st time plus 22 times of Semen Coiciss weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 8 times of Semen Coiciss weight, extracts 16h, filter to get filtrate the 2, the 3rd time and Jia 9 The water of times Semen Coiciss weight, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate and is 4 times of Semen Coiciss weight, filtration obtain final product Semen Coiciss extracting solution.
Radix Paeoniae Alba coarse powder 100g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 23 times of Radix Paeoniae Alba weight, carries 1.5h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 18 times of Radix Paeoniae Alba weight, extract 1h, filter to get filtrate the 2, the 3rd time plus 9 times amount water, 0.5h is extracted, 3 are filtered to get filtrate, filtrate 1,2,3 is merged, it is 4 times of Radix Paeoniae Alba weight that heating is concentrated into the volume of filtrate, is filtered Obtain final product white paeony root extract.
Fructus Forsythiae coarse powder 100g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 19 times of Fructus Forsythiae weight, carries 1.5h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 13 times of Fructus Forsythiae weight, extract 1h, filter to get filtrate the 2, the 3rd time plus 9 times of Fructus Forsythiaes The water of weight, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is Fructus Forsythiae weight that heating is concentrated into the volume of filtrate 3 times, filtration obtain final product Fructus Forsythiae extracting solution.
Radix Glycyrrhizae coarse powder 100g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 19 times of Radix Glycyrrhizae weight, carries 1.5h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 15 times of Radix Glycyrrhizae weight, extract 1h, filtered to get filtrate the 2, the 3rd time plus 8 Radix Glycyrrhizaes weight The water of amount, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is the 3 of Radix Glycyrrhizae weight that heating is concentrated into the volume of filtrate Times, filtration obtains final product Radix Glycyrrhizae extract.
Flos Carthami 100g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 20 times of Flos Carthami weight, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 16 times of Flos Carthami weight, extract 1h, and filter to get filtrate the 2, the 3rd time plus 10 times of Flos Carthami weights The water of amount, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is the 3 of Flos Carthami weight that heating is concentrated into the volume of filtrate Times, filtration obtains final product Flos Carthami extract.
Herba Leonuri coarse powder 100g is weighed, 0.5h, heating decoction extraction 3 times, the 1st time plus 19 times of Herba Leonuri weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 13 times of Herba Leonuri weight, extracts 1h, filter to get filtrate the 2, the 3rd time and Jia 8 The water of times Herba Leonuri weight, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate and is 4 times of Herba Leonuri weight, filtration obtain final product Herba Leonuri extracting solution.
Poria coarse powder 100g is weighed, 0.5h, heating decoction extraction 3 times, the 1st time plus 19 times of Poria weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 13 times of Poria weight, extracts 1h, filter to get filtrate the 2, the 3rd time and Jia 9 The water of times Poria weight, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate and is 5 times of Poria weight, filtration obtain final product Poria extracting solution.
Caulis Spatholobi coarse powder 120g is weighed, 0.5h, heating decoction extraction 3 times, the 1st time plus 15 times of Caulis Spatholobi weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 12 times of Caulis Spatholobi weight, extracts 1h, filter to get filtrate the 2, the 3rd time and Jia 8 The water of times Caulis Spatholobi weight, extracts 0.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into the volume of filtrate and is 3 times of Caulis Spatholobi weight, filtration obtain final product Caulis Spatholobi extracting solution.
Described essence is Fructus Citri Limoniae essence.
Described coarse powder all can be sieved by No. two, wherein be mixed with can be by the powder of No. four sieves 30%.
75% described ethanol refers to the ethanol solution that volume fraction is 75%.
A kind of preparation method of antiinflammatory anti-acne facial treatment milk, comprises the following steps:
A) take a clean beaker and weigh Oleum Hippophae 0.6g, hazelnut oil 0.7g, mango butter 0.6g and Ah glycerol 0.5g, and Compound emulsifying agent AC-4022g is added in this beaker, heating in water bath on 75 DEG C of water-baths is put, as oil phase;
B) 6ml distilled water is measured, heating in water bath on 75 DEG C of water-baths is put, as water phase;
C) treat that oil phase is identical with water phase temperature, oil phase is added in water phase in thread shape, it is stirring while adding until being formed Uniform emulsion basess 1;
D) Flos Lonicerae extractive solution 3g, Semen Coiciss extracting solution 4g, yellow white paeony root extract 3g, Fructus Forsythiae extracting solution 3g are weighed respectively, Radix Glycyrrhizae extract 3g, Herba Leonuri extracting solution 2g, Poria extracting solution 2g, Flos Carthami extract 2g, white paeony root extract 2g, Caulis Spatholobi are carried Take liquid 2g, mix homogeneously, as solution 1;
E) 0.5g sodium alginates are weighed, is dispensed in 30ml distilled water, form coagulant liquid 1;
F) 0.5g Carbopol 941s are weighed, is dispensed in 30ml distilled water, form coagulant liquid 2;
G) ethyl hydroxybenzoate 0.2g is weighed, the dissolving of 75% ethanol of 2ml is added, is formed antiseptic solution;
H) by solution 1, coagulant liquid 1, coagulant liquid 2, antiseptic solution, essence 0.2ml, emulsion basess 1 are added, is sufficiently stirred for Mix homogeneously, obtains final product antiinflammatory anti-acne facial treatment milk.
Embodiment 3
Flos Lonicerae 100g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 15 times of Flos Lonicerae weight, carries 1.5h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 10 times of Flos Lonicerae weight, extract 1.0h, filtered to get filtrate the 2, the 3rd time plus 8 times The water of Flos Lonicerae weight, extracts 1.0h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is gold that heating is concentrated into the volume of filtrate 3 times of Flos Lonicerae weight, filtration obtain final product Flos Lonicerae extractive solution.
Semen Coiciss coarse powder 150g is weighed, 0.8h, heating decoction extraction 3 times, the 1st time plus 15 times of Semen Coiciss weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 10 times of Semen Coiciss weight, extracts 1.0h, filter to get filtrate the 2, the 3rd time Plus the water of 8 times of Semen Coiciss weight, 1.0h to be extracted, 3 are filtered to get filtrate, filtrate 1,2,3 is merged, heating is concentrated into the volume of filtrate For 3 times of Semen Coiciss weight, filtration obtains final product Semen Coiciss extracting solution.
Radix Paeoniae Alba coarse powder 100g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 20 times of Radix Paeoniae Alba weight, carries 1.5h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 15 times of Radix Paeoniae Alba weight, extract 1.0h, filter to get filtrate the 2, the 3rd time plus 8 times in vain The water of Chinese herbaceous peony weight, extracts 1.0h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is that the Radix Paeoniae Alba weighs that heating is concentrated into the volume of filtrate 3 times of amount, filtration obtain final product white paeony root extract.
Fructus Forsythiae coarse powder 150g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 15 times of Fructus Forsythiae weight, carries 1.5h is taken, is filtered to get filtrate the 1, the 2nd time and is added the water of 12 times of Fructus Forsythiae weight, extract 1.0h, filtered to get filtrate the 2, the 3rd time plus 8 times and connect Stick up the water of weight, extract 1.0h, filter to get filtrate 3, filtrate 1,2,3 is merged, it is Fructus Forsythiae weight that heating is concentrated into the volume of filtrate 4 times of amount, filtration obtain final product Fructus Forsythiae extracting solution.
Radix Glycyrrhizae coarse powder 150g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 20 times of Radix Glycyrrhizae weight, carries Take 1.5h, the water of filter to get filtrate the 1, the 2nd time plus 15 times of Radix Glycyrrhizae weight extracts 1.0h, filter to get filtrate the 2, the 3rd time plus 8 times it is sweet The water of careless weight, extracts 1.0h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is that Radix Glycyrrhizae weighs that heating is concentrated into the volume of filtrate 3 times of amount, filtration obtain final product Radix Glycyrrhizae extract.
Flos Carthami 150g is weighed, 0.5h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 20 times of Flos Carthami weight, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 15 times of Flos Carthami weight, extract 1.0h, and filter to get filtrate the 2, the 3rd time plus 8 times of Flos Carthamis The water of weight, extracts 1.0h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and it is Flos Carthami weight that heating is concentrated into the volume of filtrate 3 times, filtration obtain final product Flos Carthami extract.
Herba Leonuri coarse powder 150g is weighed, 0.5h, heating decoction extraction 3 times, the 1st time plus 20 times of Herba Leonuri weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 15 times of Herba Leonuri weight, extracts 1.0h, filter to get filtrate the 2, the 3rd time Plus the water of 8 times of Herba Leonuri weight, 1.0h to be extracted, 3 are filtered to get filtrate, filtrate 1,2,3 is merged, heating is concentrated into the volume of filtrate For 3 times of Herba Leonuri weight, filtration obtains final product Herba Leonuri extracting solution.
Poria coarse powder 150g is weighed, 0.5h, heating decoction extraction 3 times, the 1st time plus 18 times of Poria weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 13 times of Poria weight, extracts 1.0h, filter to get filtrate the 2, the 3rd time Plus the water of 8 times of Poria weight, 1.0h to be extracted, 3 are filtered to get filtrate, filtrate 1,2,3 is merged, heating is concentrated into the volume of filtrate For 6 times of Poria weight, filtration obtains final product Poria extracting solution.
Caulis Spatholobi coarse powder 100g is weighed, 0.5h, heating decoction extraction 3 times, the 1st time plus 20 times of Caulis Spatholobi weight are soaked Water, extracts 1.5h, filters to get filtrate the 1, the 2nd time and adds the water of 16 times of Caulis Spatholobi weight, extracts 1.0h, filter to get filtrate the 2, the 3rd time Plus the water of 8 times of Caulis Spatholobi weight, 1.0h to be extracted, 3 are filtered to get filtrate, filtrate 1,2,3 is merged, heating is concentrated into the volume of filtrate For 3 times of Caulis Spatholobi weight, filtration obtains final product Caulis Spatholobi extracting solution.
Described essence is the mixture of Bulbus Lilii essence and peach flavor by weight 11.
Described coarse powder all can be sieved by No. two, wherein be mixed with can be by the powder of No. four sieves 40%.
75% described ethanol refers to the ethanol solution that volume fraction is 75%.
A kind of preparation method of antiinflammatory anti-acne facial treatment milk, comprises the following steps:
A) take a clean beaker and weigh Oleum Hippophae 0.5g, hazelnut oil 0.2g, mango butter 0.5g and Ah glycerol 0.2g, and Compound emulsifying agent AC-4021g is added in this beaker, heating in water bath on 80 DEG C of water-baths is put, as oil phase;
B) 10ml distilled water is measured, heating in water bath on 80 DEG C of water-baths is put, as water phase;
C) treat that oil phase is identical with water phase temperature, oil phase is added in water phase in thread shape, it is stirring while adding until being formed Uniform emulsion basess 1;
D) Flos Lonicerae extractive solution 2g, Semen Coiciss extracting solution 2g, Fructus Forsythiae extracting solution 2g, Radix Glycyrrhizae extract 1g, benefit are weighed respectively Herba Linderniae Crustaceae extracting solution 1g, Poria extracting solution 2g, Flos Carthami extract 2g, white paeony root extract 1g, Caulis Spatholobi extracting solution 2g, mixing are equal It is even, as solution 1;
E) 1g sodium alginates are weighed, is dispensed in 50ml distilled water, form coagulant liquid 1;
F) 1g Carbopol 941s are weighed, is dispensed in 50ml distilled water, form coagulant liquid 2;
G) ethyl hydroxybenzoate 0.36g is weighed, the dissolving of 75% ethanol of 3ml is added, is formed antiseptic solution;
H) solution 1, coagulant liquid 1, coagulant liquid 2, antiseptic solution, essence 0.25ml are added into emulsion basess 1, is sufficiently stirred for Mix homogeneously, obtains final product antiinflammatory anti-acne facial treatment milk.
The physical and chemical index of embodiment 1,2,3 is as follows:
(1) character
This product is that viscosity is suitable, fine and smooth uniform, the good milky emulsion of stretchability.
(2) pH value inspection
A small amount of emulsion is dipped with the pH reagent paper of moistening, pH is 6-7.
(3) caloric test
Emulsion is packaged in transparency emulsion bottle, in 4 DEG C of refrigerator cold-storage observations in a week or so without lamination.In 55 DEG C Calorstat in 24h, emulsion is without layering, the phenomenon such as spoiled.
(4) centrifugal test
Emulsion is packaged in into 3000r/min centrifugation 20min in tool plug test tube, without lamination.
(5) irritation test, sensitivity test
White mice back cuts off hair, smears the emulsion for preparing by embodiment 1,2,3 respectively in cutting plucked position, and does not apply Position is compared, as a result no zest and anaphylaxiss.
Each 1 gram of the emulsion that respectively prepared by Example 1,2,3 is applied in volunteer's gesture and facial expression, observes, do not have after spending 30 minutes There is rubescent, dermexanthesis, foaming phenomena.
(6) room temperature places test
1,2,3 made emulsion of embodiment is placed in lotion pump, investigation 6 months is stored at room temperature, without lamination, with after Feel unchanged, abnormal smells from the patient is unchanged.
(7) antiinflammatory anti-acne effect
Serious 45 people of volunteer of facial acne is chosen, is divided into three groups, per group of 15 people, by the emulsion obtained by embodiment 1-3 It is respectively used at three groups of volunteer's facial acne symptom, volunteer is generally comfortable on, and acne lightens, does not stay acne print.Jing mono- The continuous use of section time, the situation of acne are substantially disappeared.
(8) resultant effect
Following with effect for feeling to evaluate the emulsion that embodiment 1,2,3 is produced on probation.Scored using public-opinion poll Method, chooses the facial acne patient of 90 25-35 year age brackets as object on probation, is arbitrarily divided into three groups, respectively with enforcement Emulsion prepared by example 1,2,3.Daily using twice, use time is two months.Every using effect total score is 5 points:5 points for most High score, represents fine, very satisfied;4 points is preferable;3 points is to receive;Less than 3 points is bad, it is impossible to received.It is below Every average.The results are shown in Table 1:
1 resultant effect of table is investigated
In sum, the made emulsion antiinflammatory anti-acne skin effect of the present invention is good, does not gently stimulate, does not form a scab, heat clearing away Removing toxic substances, adjusts skin metabolic capacity.

Claims (10)

1. a kind of antiinflammatory anti-acne facial treatment milk, it is characterised in that described emulsion includes following material:
2. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described Flos Lonicerae extractive solution, Semen Coiciss extracting solution is prepared by the following method respectively:
Flos Lonicerae 50-100g is weighed, 0.5-0.8h, heating decoction extraction 3 times, the 1st time plus 15-20 times of Flos Lonicerae weight is soaked Water, extracts 1.0-2h, filters to get filtrate the 1, the 2nd time and adds the water of 10-15 times of Flos Lonicerae weight, extracts 0.5-1.5h, filter and must filter Liquid 2, the water of the 3rd time plus 8-15 times of Flos Lonicerae weight extract 0.5-1.5h, filter to get filtrate 3, filtrate 1,2,3 are merged, heating The volume for being concentrated into filtrate is 3-6 times of Flos Lonicerae weight, filters and obtains final product Flos Lonicerae extractive solution;
Semen Coiciss 100-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 15-25 times of Semen Coiciss weight Water, extract 1-2h, the water of filter to get filtrate the 1, the 2nd time plus 10-15 times of Semen Coiciss weight extracts 0.5-1.5h, filters and must filter Liquid 2, the water of the 3rd time plus 8-9 times of Semen Coiciss weight extract 0.5-1.5h, filter to get filtrate 3, filtrate 1,2,3 are merged, heating The volume for being concentrated into filtrate is 3-6 times of Semen Coiciss weight, filters and obtains final product Semen Coiciss extracting solution.
3. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described white paeony root extract, even Stick up extracting solution to be prepared by the following method respectively:
Radix Paeoniae Alba coarse powder 100-200g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-25 times of Radix Paeoniae Alba weight Water, extract 1-2h, the water of filter to get filtrate the 1, the 2nd time plus 15-20 times of Radix Paeoniae Alba weight extracts 0.5-1.5h, filters to get filtrate The water of the 2, the 3rd time plus 8-15 times of Radix Paeoniae Alba weight, extracts 0.5-1.5h, filters to get filtrate 3, filtrate 1,2,3 is merged, heating concentration Volume to filtrate is 2-5 times of Radix Paeoniae Alba weight, filters and obtains final product white paeony root extract;
Fructus Forsythiae coarse powder 100-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 15-20 times of Fructus Forsythiae weight Water, extract 1-2h, the water of filter to get filtrate the 1, the 2nd time plus 12-16 times of Fructus Forsythiae weight extracts 0.5-1.5h, filters to get filtrate The water of the 2, the 3rd time plus 8-12 times of Fructus Forsythiae weight, extracts 0.5-1.5h, filters to get filtrate 3, filtrate 1,2,3 is merged, heating concentration Volume to filtrate is 3-6 times of Fructus Forsythiae weight, filters and obtains final product Fructus Forsythiae extracting solution.
4. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described Radix Glycyrrhizae extract passes through It is prepared by following methods:
Radix Glycyrrhizae coarse powder 100-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-30 times of Radix Glycyrrhizae weight Water, extract 1-2h, the water of filter to get filtrate the 1, the 2nd time plus 15-20 times of Radix Glycyrrhizae weight extracts 0.5-1.5h, filters to get filtrate The water of the 2, the 3rd time plus 8-15 times of Radix Glycyrrhizae weight, extracts 0.5-1.5h, filters to get filtrate 3, filtrate 1,2,3 is merged, heating concentration Volume to filtrate is 3-6 times of Radix Glycyrrhizae weight, filters and obtains final product Radix Glycyrrhizae extract.
5. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described Flos Carthami extract passes through It is prepared by following methods:
Flos Carthami 100-150g is weighed, 0.5-0.8h is soaked, heating decocts the water for extracting 3 times, the 1st time plus 20-25 times of Flos Carthami weight, 1-2h is extracted, the water of filter to get filtrate the 1, the 2nd time plus 15-20 times of Flos Carthami weight extracts 0.5-1.5h, filter to get filtrate the 2, the 3rd The water of secondary plus 8-15 times of Flos Carthami weight, extracts 0.5-1.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, and heating is concentrated into filter 3-6 times for Flos Carthami weight of the volume of liquid, filtration obtains final product Flos Carthami extract.
6. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described Herba Leonuri extracting solution leads to Cross following methods preparation:
Herba Leonuri coarse powder 90-150g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-25 times of Herba Leonuri weight The water of amount, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 15-20 times of Herba Leonuri weight, extracts 0.5-1.5h, filter Filtrate 2, the water of the 3rd time plus 8-15 times of Herba Leonuri weight extract 0.5-1.5h, filter to get filtrate 3, and filtrate 1,2,3 is merged, plus It is 3-6 times of Herba Leonuri weight that heat is concentrated into the volume of filtrate, filters and obtains final product Herba Leonuri extracting solution.
7. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described Poria extracting solution leads to Cross following methods preparation:
Poria coarse powder 100-150g is weighed, 0.5-0.8h after crushing, is soaked, heating is decocted extracts 3 times, the 1st time plus 18-24 times The water of Poria weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 13-18 times of Poria weight, extracts 0.5- 1.5h, the water of filter to get filtrate the 2, the 3rd time plus 8-13 times of Poria weight extract 0.5-1.5h, filter to get filtrate 3, by filtrate 1st, 2,3 merge, and it is 3-6 times of Poria weight that heating is concentrated into the volume of filtrate, filters and obtains final product Poria extracting solution.
8. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described Caulis Spatholobi extracting solution leads to Cross following methods preparation:
Caulis Spatholobi coarse powder 100-120g is weighed, 0.5-0.8h is soaked, heating is decocted extracts 3 times, the 1st time plus 20-25 times of Caulis Spatholobi The water of weight, extracts 1-2h, filters to get filtrate the 1, the 2nd time and adds the water of 16-20 times of Caulis Spatholobi weight, extract 0.5-1.5h, filters Filtrate 2, the water of the 3rd time plus 8-16 times of Caulis Spatholobi weight extracts 0.5-1.5h, filters to get filtrate 3, and filtrate 1,2,3 is merged, It is 3-6 times of Caulis Spatholobi weight that heating is concentrated into the volume of filtrate, filters and obtains final product Caulis Spatholobi extracting solution.
9. a kind of antiinflammatory anti-acne facial treatment milk according to claim 1, it is characterised in that described essence is selected from rose One or more in essence, Fructus Citri Limoniae essence, Bulbus Lilii essence, peach flavor, osmanthus flower fragrance, green cucumber essence.
10. a kind of preparation method of antiinflammatory anti-acne facial treatment milk, it is characterised in that comprise the following steps:
A) take a clean beaker and weigh Oleum Hippophae 0.5-1g, hazelnut oil 0.2-1g, mango butter 0.5-1g and Ah glycerol 0.2-1g, And compound emulsifying agent AC-4021-3g is added in this beaker, heating in water bath on 70-90 DEG C of water-bath is put, as oil phase;
B) 10-20ml distilled water is measured, heating in water bath on 70-90 DEG C of water-bath is put, as water phase;
C) treat that oil phase is identical with water phase temperature, water is mutually added in oil phase in thread shape, it is stirring while adding until forming uniform Emulsion basess 1;
D) Flos Lonicerae extractive solution 1-8g is weighed respectively, and Semen Coiciss extracting solution 1-15g, Herba Leonuri extracting solution 0.5-5g, Fructus Forsythiae are extracted Liquid 1-7g, Poria extracting solution 1-7g, Radix Glycyrrhizae extract 0.5-5g, white paeony root extract 0.5-5g, Caulis Spatholobi extracting solution 1-8g are red Flower extracting solution 1-8g, mix homogeneously, as solution 1;
E) 0.1-1g sodium alginates are weighed, is dispensed in 20-50ml distilled water, form coagulant liquid 1;
F) 0.1-1g Carbopol 941s are weighed, is dispensed in 20-50ml distilled water, form coagulant liquid 2;
G) ethyl hydroxybenzoate 0.16-0.36g is weighed, is dissolved in adding the ethanol that 1-3ml volume fractions are 75%, is formed preservative Solution;
H) solution 1, coagulant liquid 1, coagulant liquid 2, antiseptic solution, essence 0.05-0.25ml are separately added in emulsion basess 1, It is thoroughly mixed uniformly, obtains final product antiinflammatory anti-acne facial treatment milk.
CN201611174498.9A 2016-12-19 2016-12-19 Anti-inflammatory acne-removing skin-care lotion and preparation method thereof Expired - Fee Related CN106511211B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107625668A (en) * 2017-09-29 2018-01-26 武汉华士特工业生物技术开发有限公司 A kind of anti-acne moisturizing sun cream and preparation method thereof
CN108042459A (en) * 2018-01-17 2018-05-18 广西达庆生物科技股份有限公司 A kind of antiallergic condensation
CN109044865A (en) * 2018-09-10 2018-12-21 新疆庄子实业有限公司 A kind of safflower lotion and preparation method thereof
CN109260085A (en) * 2018-11-08 2019-01-25 中山爱护日用品有限公司 A kind of natural baby skin protection frost and preparation method thereof

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CN104971033A (en) * 2015-06-28 2015-10-14 青岛宇星智能科技开发有限公司 Efficient facial mask with effects of removing acne and acne marks
CN105796457A (en) * 2016-03-11 2016-07-27 皖南医学院 Scar and pockmark removing lotion rich in natural extracts and preparation method of lotion
CN105919863A (en) * 2016-05-30 2016-09-07 皖南医学院 Acne removing and skin beautifying cream rich in extracts of natural ingredients and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN104971033A (en) * 2015-06-28 2015-10-14 青岛宇星智能科技开发有限公司 Efficient facial mask with effects of removing acne and acne marks
CN105796457A (en) * 2016-03-11 2016-07-27 皖南医学院 Scar and pockmark removing lotion rich in natural extracts and preparation method of lotion
CN105919863A (en) * 2016-05-30 2016-09-07 皖南医学院 Acne removing and skin beautifying cream rich in extracts of natural ingredients and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107625668A (en) * 2017-09-29 2018-01-26 武汉华士特工业生物技术开发有限公司 A kind of anti-acne moisturizing sun cream and preparation method thereof
CN108042459A (en) * 2018-01-17 2018-05-18 广西达庆生物科技股份有限公司 A kind of antiallergic condensation
CN109044865A (en) * 2018-09-10 2018-12-21 新疆庄子实业有限公司 A kind of safflower lotion and preparation method thereof
CN109260085A (en) * 2018-11-08 2019-01-25 中山爱护日用品有限公司 A kind of natural baby skin protection frost and preparation method thereof

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