CN104825347A - Medical biological whitening and spot-removing dressing and preparation method thereof - Google Patents
Medical biological whitening and spot-removing dressing and preparation method thereof Download PDFInfo
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- CN104825347A CN104825347A CN201510269860.XA CN201510269860A CN104825347A CN 104825347 A CN104825347 A CN 104825347A CN 201510269860 A CN201510269860 A CN 201510269860A CN 104825347 A CN104825347 A CN 104825347A
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- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- -1 sulfur aminoacid Chemical class 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000003867 tiredness Effects 0.000 description 1
- 208000016255 tiredness Diseases 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention relates to medical dressing, and in particular relates to medical biological whitening and spot-removing dressing and a preparation method thereof. D-arbutin, camellia oil, linoleic acid, almond oil and astaxanthin are taken as main components for whitening and spot removing, and together with components such as azone, glycerinum, vitamin C and vitamin E, and due to reasonable matching, the medical biological whitening and spot-removing dressing can be prepared, the components can effectively infiltrate into the base layer of skin, the activity of tryosinase can be effectively inhibited, oxygen free radicals can be efficiently eliminated, generation of melanin can be prevented, existing melanin can be also decomposed, cells can be activated, spots on faces can be faded, skin problems caused by chromatosis such as chloasma, malar rash and age pigment can be gradually solved, damage caused by chemical components such as hormone to skin can be remedied, the effects of comprehensive and rapid treatment on both symptoms and root causes can be achieved, and the skin can be whitened and moistened and is glossy and smooth. The medical biological whitening and spot-removing dressing is simple in preparation method, convenient to use and convenient to popularize.
Description
Technical field
The present invention relates to medical dressing technical field, be specifically related to a kind of medical bio whitening and spot-eliminating dressing and preparation method thereof.
Background technology
Everybody has a love of beauty, and along with improving constantly of people's living standard, the pursuit of people to U.S. also improves constantly, and for most of women, all wishes the appearance of change oneself and have the pale colour of skin.But for women, with advancing age, the metabolism of health slows down, and melanin cannot normally be mediated, and at horny layer formation of deposits speckle, by and form chloasma, black speck and mottle; Life is nervous, works and rests irregular, and various environmental pollution, causes that self-resistance declines, endocrine disturbance, makes interior free yl activate, and increases melanin abnormal secretion.And for the partially black women of some born skins, whitening their unremitting pursue especially.
Such as, application number be 201310552253.5 Chinese invention patent be disclosed a kind of skin-whitening speckle-removing cream, it is characterized in that, the active component mainly containing, for example lower weight proportion in ointment bases: β-arbutin 5 parts, glycyrrhizic acid dipotassium 1 part, azone 1 part.But the said goods whitening and speckle dispelling effect is still undesirable, a kind of more efficiently whitening and speckle dispelling product is not had in prior art yet, in view of this, be necessary to provide a kind of more efficiently whitening and speckle dispelling product, effectively can solve the skin problem that the pigmentations such as chloasma, butterfly spot and senile plaque cause, and there is remarkable whitening effect.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, the medical bio whitening and spot-eliminating dressing providing a kind of whitening and speckle dispelling effective.
To achieve these goals, the present invention adopts following technical scheme: the dressing of a kind of medical bio whitening and spot-eliminating, is characterized in that: the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 2-9%
Camellia oil 2-9%
Linoleic acid 0.5-3.5%
Azone 0.4-1.2%
Almond oil 7-15%
Glycerol 7-15%
Astaxanthin 1-5%
Vitamin C 1-4%
Vitamin E 0.1-2%
Ethanol 6-14%
Purified water surplus.
Preferably, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 2-5%
Camellia oil 2-5%
Linoleic acid 0.5-2%
Azone 0.4-0.8%
Almond oil 7-10%
Glycerol 7-10%
Astaxanthin 1-3%
Vitamin C 1-2%
Vitamin E 0.1-1%
Ethanol 6-10%
Purified water surplus.
Another is preferred, and the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 5-9%
Camellia oil 5-9%
Linoleic acid 2-3.5%
Azone 0.8-1.2%
Almond oil 10-15%
Glycerol 10-15%
Astaxanthin 3-5%
Vitamin C 2-4%
Vitamin E 1-2%
Ethanol 10-14%
Purified water surplus.
More preferred, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 5%
Camellia oil 5%
Linoleic acid 2%
Azone 0.8%
Almond oil 10%
Glycerol 10%
Astaxanthin 3%
Vitamin C 2%
Vitamin E 1%
Ethanol 10%
Purified water surplus.
Another is more preferred, and the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 4%
Camellia oil 5%
Linoleic acid 1.5%
Azone 0.9%
Almond oil 9%
Glycerol 11%
Astaxanthin 3%
Vitamin C 2%
Vitamin E 1%
Ethanol 10%
Purified water surplus.
Described astaxanthin is excellent A astaxanthin.
Described ethanol to be mass fraction be 75% ethanol.
The preparation method of described a kind of medical bio whitening and spot-eliminating dressing, it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
On this basis, the dressing of a kind of medical bio whitening and spot-eliminating, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 2-9%
Camellia oil 2-9%
Linoleic acid 0.5-3.5%
Azone 0.4-1.2%
Almond oil 7-15%
Glycerol 7-15%
Astaxanthin 1-5%
Vitamin C 1-4%
Vitamin E 0.1-2%
Ethanol 6-14%
Rhizoma Atractylodis Macrocephalae extracting solution 2-6%
Polygoni cuspidati,radix extracting solution 1-3%
Indigo Naturalis extracting solution 1-3%
Radix Et Rhizoma Nardostachyos extracting solution 1-3%
Purified water surplus.
The preparation method of described a kind of medical bio whitening and spot-eliminating dressing, it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
D-Arbutin of the present invention and D-Arbutin are one of derivants of Arbutin, effectively can suppress the effect of Tyrosine ferment in skin histology, its effect or even 10 of hydroquinone times, are 350 times of general Arbutin.In the skin test of animal, this D-Arbutin can allow whitening skin quickly and effectively, and after stopping using, effect still can maintain the time of 8 weeks nearly.In the clinical research of human body, local uses can obtain obvious skin lightening effect in 12 week of D-Arbutin, tans by the sun speckle and obscure colour of skin situation, have good improvement effect especially for day optical activity.
Camellia oil of the present invention is unsaturated fatty acids acid lipid, obtains from tea oil tree seed.The Heat stability is good of camellia seed oil; also there is the defencive function of the basic nature to skin; and containing the Natural Antioxidants such as carotene and tea polyphenols; have the specific function of skin care, it is less that Camellia oil records its surface tension through experiment, close with olive oil; diffusion coefficient is large; skin is easy to expansion absorb, does not need additionally to add emulsifying agent, the skin protection feed of base oil that therefore Camellia oil can be used as a kind of good properties is applied.Camellia oil energy uvioresistant, prevents sunburn and reduces wrinkle, very effective to chloasma sunburn; Camellia oil contains abundant natural Vitamin E, tea polyphenols, Squalene, unsaturated fatty acid etc., and these all possess effect of beautifying and anti-aging, and unsaturated fatty acid can suppress fat, the function of prevention three-hypers, and life-time service makes the skin smooth of people, moistens.
Linoleic acid of the present invention is crude vegetal, can promote D-Arbutin synergistic function, can also the activity of effective restraint of tyrosinase, reduces melanin and is formed, have VE effect, also can moisturizing, irritation, hypo-allergenic.
Azone of the present invention is used as penetrating agent, for cream frost all kinds of in cosmetics and hair care product; Azone all has obvious transdermal to help the effect of oozing to oleophylic, hydrophilic medicament and active component, keratodermatitis and lipid are interacted, reduce the phase inversion temperature of active substance to lipid in horny layer gap, add mobility, diffusional resistance in horny layer of medicine or active additive is reduced, therefore plays and very strong shortly ooze effect.
Almond oil rich in mineral substances of the present invention, protein and various vitamin, be the splendid vegetable oil of a kind of skin care and moisturizing effect, be applicable to various skin quality.It can alleviate skin pruritus phenomenon effectively, eliminates red and swollen, dry and inflammation.Almond oil can make skin recover smooth soft and fine, if life-time service can eliminate striae gravidarum effectively.Because almond oil is very gentle, therefore connecting baby can use, and in addition for the myalgia that hyperkinesia causes, if can strengthen cell band oxygen function with Semen pruni armeniacae oil massage, allaying tiredness and carbonic acid are accumulated, and have analgesia and abirritant effect.In addition, almond oil can anti-canthus wrinkle.
Glycerol has lubrication, and the dosage form of formation has toughness and protectiveness, makes to have soapy feeling, and can keep longer wetting time as wetting agent, sliding capability is good, can extend actor at mucosa local efficacy, have good lubricant effect; Can be used as hygroscopic agent, viscosity modifier and solvent.
Astaxanthin is one of the strongest in the world Natural antioxidant; oxygen-derived free radicals in effective scavenger cell; strengthen cell regeneration ability; maintain the accumulation of organism balance and minimizing senile cell; Cell protection and DNA health from inside to outside; thus protection skin health, promote hair growth, defying age, relieving sports fatigue, to invigorate.Astaxanthin has the molecular structure of its uniqueness, the absorption peak of its material is exactly about 470nm, close with UVA wavelength (380-420nm), therefore the astaxanthin of trace just can absorb a large amount of UVA, like the natural sun-screening agents of uniqueness the most perfect on the earth, as natural anti-sunshade bedding whole body, can ultraviolet radiation preventing, the UV-induced free radical of cancellation efficiently, reduce the injury of ultraviolet to skin and prevent.In addition, it also can restore the skin destroyed by ultraviolet burn rapidly.Astaxanthin then significantly can weaken the destruction of ROS and NMP to skin corium collagen protein, elastin, ensures the homergy of skin.
Ascorbic effect of the present invention and function: vitamin C is that antibody and collagen are formed, tissue repairing's (comprising some redox), the metabolism of phenylalanine, tyrosine, folic acid, the utilization of ferrum, carbohydrate, the synthesis of fat, protein, maintain immunologic function, hydroxylation and hydroxytryptamine, keep the complete of blood vessel, promote that the institutes such as nonheme iron absorption are required, vitamin C also has antioxidation simultaneously, free radical resisting, the formation of restraint of tyrosinase, thus reach whitening, effect of light speckle.In human body, vitamin C is high-efficiency antioxidant agent, is used for alleviating the oxidation stress (oxidative stress) of ascorbate peroxidase enzyme (ascorbate peroxidase) substrate.Also have in many important biosynthetic processes and also need vitamin C participation role.
The effect of vitamin E of the present invention and function: protection skin, makes skin flexible.The protein active structure of vitamin E energy stabilizing cell membrane, promotes the normal development of muscle and keeps the elasticity of skin, making skin and health maintain vigour; Vitamin E enters Skin Cell and more can directly help skin to the infringement of free radical resisting, ultraviolet and pollutant, reduces the deposition of cicatrix and pigment; The healing of accelerated in wounds.Slow down aging, effectively reduces the generation of wrinkle, the appearance retained youth.Vitamin E is a kind of fatsoluble vitamin, is one of topmost antioxidant, can prevent fatty compound, vitamin A, selenium (Se), two kinds of sulfur aminoacid and ascorbic Oxidation, improves the effect of vitamin A; Prevent skin from following the string until aging because of some chronic or recessive injuries, prevent skin aging.
Ethanol can promote that in cosmetics skin absorbs, and contribute to active component transdermal, and that is ethanol plays the effect promoting cosmetic effect in fact.In addition, ethanol contributes to control oil, promotes coming off of waste and old cutin, the convergence effect had, and ethanol is disinfectant known best so far, fabulous cleaning agent and degreasing agent at cosmetic field.
On this basis, the present invention also can add a certain amount of Chinese medicine extraction liquid, and the Chinese medicine extraction liquid that the present invention adopts and above-mentioned raw materials cooperatively interact, and whitening and speckle dispelling effect is even better, and Chinese medicine extraction liquid used has following effect:
The Rhizoma Atractylodis Macrocephalae has heat clearing and damp drying, parasite killing, treatment skin tinea, de-black flour, again the effect of firm tooth black hair, the light speckle of promotion melanin metabolism.Rhizoma Atractylodis Macrocephalae extracting solution mixes immersion by 80 whitish eye art powder and 100 degrees Celsius of hot water through 1:5 ratio to obtain with 80 eye mesh screens filtrations after 12 hours.
Resveratrol in polygoni cuspidati,radix and emodin have anti-oxidation characteristics widely, and the red anthrone of other composition, physcione and chrysophanic acid all have anti-inflammatory, arthritis of dispelling and antimicrobial acivity.Polygoni cuspidati,radix extracting solution mixes immersion by 80 order polygoni cuspidati,radix powder and 100 degrees Celsius of hot water through 1:5 ratio to obtain with 80 eye mesh screens filtrations after 12 hours.
Indigo Naturalis has whitening, antiinflammatory, effect of acne removing print.Indigo Naturalis extracting solution mixes immersion by 80 bluish eyes black pigment used by women in ancient times to paint their eyebrows powder and 100 degrees Celsius of hot water through 1:5 ratio to obtain with 80 eye mesh screens filtrations after 12 hours.
Radix Et Rhizoma Nardostachyos has Xin Xianghang and falls apart, and kind spleen of opening is strongly fragrant and except effect of dark complexion.Radix Et Rhizoma Nardostachyos extracting solution mixes immersion by 80 order Nardostachys Roots and 100 degrees Celsius of hot water through 1:5 ratio to obtain with 80 eye mesh screens filtrations after 12 hours.
Purified water not only can be skin moisturizing as solvent.
Compared with prior art, beneficial effect is in the present invention:
(1) the present invention is with D-Arbutin, Camellia oil, linoleic acid, almond oil, astaxanthin is as the main component of whitening and speckle dispelling, and be aided with azone, glycerol, vitamin C, the compositions such as vitamin E, by rational compatibility, the basal layer that obtained medical bio whitening and spot-eliminating dressing can not only penetrate to the skin effectively, and can the activity of restraint of tyrosinase effectively, efficient scavenging activated oxygen, prevent melanic generation, the existing melanin of reduction decomposition simultaneously, activating cell, desalinate facial speckle, gradually chloasma is eliminated, butterfly spot, the skin problem that the pigmentations such as senile plaque cause, repair the damage because the chemical compositions such as hormone cause skin simultaneously, thus reach comprehensively fast, the effect for the treatment of both the principal and secondary aspects of a disease, make skin-whitening, moisten moisturizing, gloss is fine and smooth.Preparation method of the present invention is simple, easy to use, is convenient to the advantages such as popularization.
(2) biocompatibility of medical bio whitening and spot-eliminating of the present invention dressing meets GB/T 16886.11-2011 requirement.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
embodiment 1.
The dressing of a kind of medical bio whitening and spot-eliminating, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 2%
Camellia oil 2%
Linoleic acid 0.5%
Azone 0.4%
Almond oil 7%
Glycerol 7%
Astaxanthin 1%
Vitamin C 1%
Vitamin E 0.1%
Ethanol 6%
Purified water surplus.
Described astaxanthin is excellent A astaxanthin.
Described ethanol to be mass fraction be 75% ethanol.
A preparation method for medical bio whitening and spot-eliminating dressing, it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
embodiment 2.
The dressing of a kind of medical bio whitening and spot-eliminating, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 5%
Camellia oil 5%
Linoleic acid 2%
Azone 0.8%
Almond oil 10%
Glycerol 10%
Astaxanthin 3%
Vitamin C 2%
Vitamin E 1%
Ethanol 10%
Purified water surplus.
Described astaxanthin is excellent A astaxanthin.
Described ethanol to be mass fraction be 75% ethanol.
A preparation method for medical bio whitening and spot-eliminating dressing, it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
embodiment 3.
The dressing of a kind of medical bio whitening and spot-eliminating, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 4%
Camellia oil 5%
Linoleic acid 1.5%
Azone 0.9%
Almond oil 9%
Glycerol 11%
Astaxanthin 3%
Vitamin C 2%
Vitamin E 1%
Ethanol 10%
Purified water surplus.
Described astaxanthin is excellent A astaxanthin.
Described ethanol to be mass fraction be 75% ethanol.
A preparation method for medical bio whitening and spot-eliminating dressing, it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
embodiment 4.
The dressing of a kind of medical bio whitening and spot-eliminating, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 9%
Camellia oil 9%
Linoleic acid 3.5%
Azone 1.2%
Almond oil 15%
Glycerol 15%
Astaxanthin 5%
Vitamin C 4%
Vitamin E 2%
Ethanol 14%
Purified water surplus.
Described astaxanthin is excellent A astaxanthin.
Described ethanol to be mass fraction be 75% ethanol.
The preparation method of a kind of medical bio whitening and spot-eliminating dressing it comprise following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
embodiment 5.
The dressing of a kind of medical bio whitening and spot-eliminating, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 3%
Camellia oil 3%
Linoleic acid 1%
Azone 1%
Almond oil 8%
Glycerol 8%
Astaxanthin 2%
Vitamin C 2%
Vitamin E 1%
Ethanol 7%
Rhizoma Atractylodis Macrocephalae extracting solution 3%
Polygoni cuspidati,radix extracting solution 2%
Indigo Naturalis extracting solution 1%
Radix Et Rhizoma Nardostachyos extracting solution 1%
Purified water surplus.
A preparation method for medical bio whitening and spot-eliminating dressing, it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
embodiment 6.
The dressing of a kind of medical bio whitening and spot-eliminating, the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 8%
Camellia oil 8%
Linoleic acid 3%
Azone 1%
Almond oil 14%
Glycerol 14%
Astaxanthin 4%
Vitamin C 3%
Vitamin E 1%
Ethanol 12%
Rhizoma Atractylodis Macrocephalae extracting solution 5%
Polygoni cuspidati,radix extracting solution 2%
Indigo Naturalis extracting solution 2%
Radix Et Rhizoma Nardostachyos extracting solution 2%
Purified water surplus.
A preparation method for medical bio whitening and spot-eliminating dressing, it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
Adopt product prepared by embodiment 1 to 6, select 180 30-55 Mrs year use, their face has the mottle problems such as chloasma in various degree, freckle, butterfly spot and senile plaque and the partially black problem of skin.These 180 Mies are divided into 6 groups at random, wherein, 30 Mies of first group use the medical bio whitening and spot-eliminating dressing of embodiment 1,30 Mies of second group use the medical bio whitening and spot-eliminating dressing of embodiment 2,30 Mies of the 3rd group use the medical bio whitening and spot-eliminating dressing of embodiment 3,30 Mies of the 4th group use the medical bio whitening and spot-eliminating dressing of embodiment 4,30 Mies of the 5th group use the medical bio whitening and spot-eliminating dressing of embodiment 5,30 Mies of the 6th group to use the medical bio whitening and spot-eliminating dressing of embodiment 6.Select in addition 30 30-55 Mrs year use the whitening and speckle dispelling product of prior art, form matched group seven, these 30 Mies of matched group seven can other freckle removing and whitening product of unrestricted choice prior art.
Using method of the present invention: use medical bio whitening and spot-eliminating dressing 3-5g after morning and evening every day washed after the centre of the palm is warm, be applied on the face, be then softly massaged into absorption from inside to outside:
The description of product that matched group is chosen according to oneself uses.
Following table is the effect after the whitening and speckle dispelling product using each embodiment and matched group for 30 days afterwards.
Wherein, criterion of therapeutical effect is: recovery from illness: face's speckle disappears substantially; Effective: face's speckle disappears more than 50%; Effective: face's speckle disappear more than 10% or spot colors turn light; Invalid: unchanged before and after treatment.
Clinical case:
Mrs Cai, 30 years old, skin formed large stretch of mottle after being subject to ultraviolet burn, and use this product after 20 days, mottle is desalinated, and continue to use, after 45 days, mottle is desalinated greatly, after 60 days, does not substantially see there is mottle, and skin smooth is fine and smooth.
Mrs Wang, 45 years old, face is long had the concurrent chloasma of freckle, a lot of speckle dispelling product of the black Huang of skin of face, and effect is undesirable, use 4 the course for the treatment of freckle, chloasma disappearance blee bleaches, and skin is glossy.
Mrs Li, 27 years old, time conceived, face is long pregnant occasion speckle, and use a lot of speckle dispelling product after producing, some effect is undesirable, use this product after 15 days pregnant occasion speckle thin out, uses pregnant occasion speckle disappearance after 45 days, skin gloss is pale.
Ms Zhang, 44 years old, partially black on the face and have a large amount of mottle, use this product after one month, facial skin is pale, and mottle is desalinated greatly.
As can be seen here, the present invention has obvious whitening and speckle dispelling effect, and it effectively can solve the skin problem that the pigmentation such as chloasma, butterfly spot causes, and easy to use, whitening effect is remarkable.
Finally should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention; but not limiting the scope of the invention; although done to explain to the present invention with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can modify to technical scheme of the present invention or equivalent replacement, and not depart from essence and the scope of technical solution of the present invention.
Claims (10)
1. a medical bio whitening and spot-eliminating dressing, is characterized in that: the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 2-9%
Camellia oil 2-9%
Linoleic acid 0.5-3.5%
Azone 0.4-1.2%
Almond oil 7-15%
Glycerol 7-15%
Astaxanthin 1-5%
Vitamin C 1-4%
Vitamin E 0.1-2%
Ethanol 6-14%
Purified water surplus.
2. a kind of medical bio whitening and spot-eliminating according to claim 1 dressing, is characterized in that: the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 2-5%
Camellia oil 2-5%
Linoleic acid 0.5-2%
Azone 0.4-0.8%
Almond oil 7-10%
Glycerol 7-10%
Astaxanthin 1-3%
Vitamin C 1-2%
Vitamin E 0.1-1%
Ethanol 6-10%
Purified water surplus.
3. a kind of medical bio whitening and spot-eliminating according to claim 1 dressing, is characterized in that: the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 5-9%
Camellia oil 5-9%
Linoleic acid 2-3.5%
Azone 0.8-1.2%
Almond oil 10-15%
Glycerol 10-15%
Astaxanthin 3-5%
Vitamin C 2-4%
Vitamin E 1-2%
Ethanol 10-14%
Purified water surplus.
4. a kind of medical bio whitening and spot-eliminating according to claim 1 dressing, is characterized in that: the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 5%
Camellia oil 5%
Linoleic acid 2%
Azone 0.8%
Almond oil 10%
Glycerol 10%
Astaxanthin 3%
Vitamin C 2%
Vitamin E 1%
Ethanol 10%
Purified water surplus.
5. a kind of medical bio whitening and spot-eliminating according to claim 1 dressing, is characterized in that: the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 4%
Camellia oil 5%
Linoleic acid 1.5%
Azone 0.9%
Almond oil 9%
Glycerol 11%
Astaxanthin 3%
Vitamin C 2%
Vitamin E 1%
Ethanol 10%
Purified water surplus.
6. a kind of medical bio whitening and spot-eliminating according to claim 1 dressing, is characterized in that: described astaxanthin is excellent A astaxanthin.
7. a kind of medical bio whitening and spot-eliminating according to claim 1 dressing, is characterized in that: described ethanol to be mass fraction be 75% ethanol.
8. the preparation method of a kind of medical bio whitening and spot-eliminating dressing described in any one of claim 1-7, is characterized in that: it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
9. a medical bio whitening and spot-eliminating dressing, is characterized in that: the dressing of described medical bio whitening and spot-eliminating is made up of the raw material of following percentage by weight:
D-Arbutin 2-9%
Camellia oil 2-9%
Linoleic acid 0.5-3.5%
Azone 0.4-1.2%
Almond oil 7-15%
Glycerol 7-15%
Astaxanthin 1-5%
Vitamin C 1-4%
Vitamin E 0.1-2%
Ethanol 6-14%
Rhizoma Atractylodis Macrocephalae extracting solution 2-6%
Polygoni cuspidati,radix extracting solution 1-3%
Indigo Naturalis extracting solution 1-3%
Radix Et Rhizoma Nardostachyos extracting solution 1-3%
Purified water surplus.
10. the preparation method of a kind of medical bio whitening and spot-eliminating according to claim 9 dressing, is characterized in that: it comprises following preparation process:
Steps A, weighing: the D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, the purified water that weigh formula ratio;
Step B, preparation: load weighted for steps A D-Arbutin, Camellia oil, linoleic acid, azone, almond oil, glycerol, astaxanthin, vitamin C, vitamin E, ethanol, Rhizoma Atractylodis Macrocephalae extracting solution, polygoni cuspidati,radix extracting solution, Indigo Naturalis extracting solution, Radix Et Rhizoma Nardostachyos extracting solution, purified water are put into container, be stirred to evenly, namely sterilizing obtains the dressing of medical bio whitening and spot-eliminating.
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| CN104825347B (en) | 2018-06-01 |
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