CN104352400A - Freckle removing cream - Google Patents
Freckle removing cream Download PDFInfo
- Publication number
- CN104352400A CN104352400A CN201410554289.1A CN201410554289A CN104352400A CN 104352400 A CN104352400 A CN 104352400A CN 201410554289 A CN201410554289 A CN 201410554289A CN 104352400 A CN104352400 A CN 104352400A
- Authority
- CN
- China
- Prior art keywords
- parts
- extract
- skin
- chinese medicine
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses freckle removing cream, which is prepared from the following raw materials in parts by weight: 20 to 30 parts of Chinese medicinal extract, 0.1 to 1 part of L-cysteine, 0.1 to 1 part of methyl cinnamate, 1 to 5 parts of magnesium ascorbyl phosphate, 0.1 to 1 part of vitamin E, 0.05 to 0.5 part of hyaluronic acid, 0.2 to 1.3 parts of tea polyphenol, 0.2 to 1 part of procyanidine, 0.4 to 2 parts of glyceryl monostearate, 0. 1 to 0.3 part of sodium bisulfate, 3 to 6 parts of octadecanol, 1 to 4 parts of stearic acid, 1 to 6 parts of liquid paraffin, 10 to 20 parts of white Vaseline, 2 to 8 parts of glycerin, 0.1 to 0.2 part of a preservative and 20 to 30 parts of distilled water. According to the freckle removing cream, Chinese medicinal and plant extract is added, so that the activity of tyrosinase can be effectively inhibited, obvious freckle removing effects are achieved, skin is nourished, and the freckle removing cream is safe, reliable and convenient to use.
Description
Technical field
The present invention relates to cosmetic field, particularly relate to a kind of QUBAN SHUANG.
Background technology
Along with the raising of people's living standard, the requirement for cosmetics transforms from the single nursing type in past to modern functions type.Especially in recent years along with the continuous quickening of life, work rhythm, and the destruction of the environment caused due to pollution and ozone layer, make melanin form the metabolism disorder of enzyme thus cause suffering from increasing of various black spots symptom crowd.
Research finds, human body skin is obscure, mottle, chloasma, and freckle etc. are because melanin gathers at face, thus show various chromatopathy.Because melanic formation mainly occurs in melanocyte, the research of the melanin formation mechenism in melanocyte is shown, melanic formation is that in melanocyte, tryrosinase is progressively converted into melanin through intermediate such as DOPA, DOPA quinone, dopachrome, dihydroxy indoles under the effect of tryrosinase, and then transfer in angle albuminous cell, and renew along with the horny layer cycle and come off.The difference of human body complexion depends primarily on content and the distribution of eumelanin and pheomelanin, when eumelanin overruns growth and skewness, local skin will be caused to cross black or pigmentation.And the real whitening of skin will be realized, the suppression multiple melanin being formed to enzyme just seems most important.
The method of current treatment is mainly through laser speckle dispelling, although freckle effect instant effect, needs of patients bears sensation of pricking, and very easily recurs, so be not best Therapeutic Method for patient; Also can use some corrosive medicines or decolouring ointment coating affected part, impel skin lesion place skin ulcer speckle to come off; Also useful Chinese medicine by enriching yin and nourishing kidney, depressed liver-energy dispersing and QI regulating, in and QI and blood etc. be equipped with whole body therapeutic.But these methods are not can cause great injury to skin, utilize Chinese medicine to nurse one's health but to decoct medicinal herbs the time long, preparation bothers, and is difficult to adhere to, thus does not reach the ideal effect of speckle dispelling.
Summary of the invention
Embodiment of the present invention technical problem to be solved is, provides a kind of QUBAN SHUANG, and adding Chinese medicine and plant extract can the activity of effective restraint of tyrosinase, freckle effect obviously, nourishes rough skin, safe and reliable, easy to use.
In order to solve the problems of the technologies described above, embodiments provide a kind of QUBAN SHUANG, the preparation of raw material comprising following weight portion forms:
Chinese medicine extract 20 ~ 30 parts, Cys 0.1 ~ 1 part, methyl cinnamate 0.1 ~ 1 part, vitamin c phosphate magnesium 1 ~ 5 part, vitamin E 0.1 ~ 1 part, hyaluronic acid 0.05 ~ 0.5 part, tea polyphenols 0.2 ~ 1.3, procyanidin 0.2 ~ 1 part, glyceryl monostearate 0.4 ~ 2 part, sodium sulfite 0.1 ~ 0.3 part, octadecanol 3 ~ 6 parts, stearic acid 1 ~ 4 part, liquid paraffin 1 ~ 6 part, white vaseline 10 ~ 20 parts, glycerol 2 ~ 8 parts, antiseptic 0.1 ~ 0.2 part, distilled water 20 ~ 30 parts.
As the improvement of such scheme, described Chinese medicine extract comprises: Radix Glycyrrhizae extract, Rhizoma Atractylodis Macrocephalae extract, Rhizoma Chuanxiong extract, Bombyx Batryticatus extract, Radix Saposhnikoviae extract, Radix Angelicae Sinensis extract.
As the improvement of such scheme, described Chinese medicine extract is by weight ratio: Radix Glycyrrhizae extract 5 ~ 15 parts, Rhizoma Atractylodis Macrocephalae extract 2 ~ 3 parts, Rhizoma Chuanxiong extract 3 ~ 10 parts, Bombyx Batryticatus extract 2 ~ 3 parts, Radix Saposhnikoviae extract 1 ~ 5 part, Radix Angelicae Sinensis extract 3 ~ 8.
As the improvement of such scheme, described antiseptic is one in ethyl hydroxybenzoate, imidazolidinyl urea, potassium sorbate or combination.
As the improvement of such scheme, described procyanidin is Semen Vitis viniferae extract.
Implement the embodiment of the present invention, there is following beneficial effect:
The present invention adopts Chinese medicine and plant extract can the activity of effective restraint of tyrosinase, reduces melanic formation, prevents and eliminate facial melanin pigmentation, freckle effect is obvious, and nourishes rough skin, improves skin quality simultaneously, and safe and reliable, easy to use, concrete effect is as follows:
(1) plurality of Chinese and plant extract is adopted to have very strong non-oxidizability in the present invention, the free radical of energy shielding of ultraviolet and removing ultraviolet induction, thus the normal function of protection melanocyte, play sun-proof effect; Meanwhile, tryrosinase and catalase activity in all right T suppression cell, thus reduce the peroxidation of melanic secretion and lipid, prevent and eliminate facial melanin pigmentation, reaching and stop and eliminate skin splash, chloasma, freckle, realizes effect of spot-eliminating beauty treatment.
(2) the present invention can help to eliminate the free radical in body, subcutaneous fat is prevented to be oxidized, strengthen the vigor of epiderm skin and hypodermal cell, avoid skin senilism, promote that collagen is formed, the destruction of prevention collagen fiber and elastic fiber, makes skin keep due elasticity and tension force, avoids skin sagging and wrinkle to produce.
(3) solve traditional Chinese medical science interior application treatment dose large, side effect is many, internal recycle malleable in body thus unhealthful, and costly, not perseverant problem.Adopt Chinese medicine inner disease outer treat, absorb fast with YAOJING, skin, consumption is little, and effect directly, makes medicine going from the exterior into the interior desalinate whitening and disappears to mottle.
(4) usage of the present invention is simple, safe and reliable, and carry storage conveniently, medical expense is low, is applicable to all ages and classes colony and uses.
(5) the present invention is not containing corrosive medicine, and use rear without peeling, changing skin phenomenon, after curing, the colour of skin is normal, not easily recurs, preventing from scar.
Detailed description of the invention
Embodiments provide a kind of QUBAN SHUANG, the preparation of raw material comprising following weight portion forms:
Chinese medicine extract 20 ~ 30 parts, Cys 0.1 ~ 1 part, methyl cinnamate 0.1 ~ 1 part, Magnesium L-Asacorbic Acid 2-O-Phosphate 1 ~ 5 part, vitamin E 0.1 ~ 1 part, hyaluronic acid 0.05 ~ 0.5 part, tea polyphenols 0.2 ~ 1.3, procyanidin 0.2 ~ 1 part, glyceryl monostearate 0.4 ~ 2 part, sodium sulfite 0.1 ~ 0.3 part, octadecanol 3 ~ 6 parts, stearic acid 1 ~ 4 part, liquid paraffin 1 ~ 6 part, white vaseline 10 ~ 20 parts, glycerol 2 ~ 8 parts, antiseptic 0.1 ~ 0.2 part, distilled water 20 ~ 30 parts.
Preferably, described Chinese medicine extract comprises: Radix Glycyrrhizae extract, Rhizoma Atractylodis Macrocephalae extract, Rhizoma Chuanxiong extract, Bombyx Batryticatus extract, Radix Saposhnikoviae extract, Radix Angelicae Sinensis extract.
Preferably, described Chinese medicine extract is by weight ratio: Radix Glycyrrhizae extract 5 ~ 15 parts, Rhizoma Atractylodis Macrocephalae extract 2 ~ 3 parts, Rhizoma Chuanxiong extract 3 ~ 10 parts, Bombyx Batryticatus extract 2 ~ 3 parts, Radix Saposhnikoviae extract 1 ~ 5 part, Radix Angelicae Sinensis extract 3 ~ 8.
Preferably, described antiseptic is one in ethyl hydroxybenzoate, imidazolidinyl urea, potassium sorbate or combination.
Preferably, described procyanidin is Semen Vitis viniferae extract.
The tyrosinase inhibitor that people know has hydroquinone, fruit acid, vitamin C, kojic acid, arbutin, but hydroquinone character extremely unstable, be easy to oxidation stain in atmosphere, and have the report causing the permanent white macula of skin, therefore in skin-whitening agents, forbid practicality, only make still can use at clinical treatment pigmentation disease; And using fruit acid de-freckle skin nursing inevitably to injure keratodermatitis, the function making skin resist extraneous infringement reduces, and also makes skin excessive water lose simultaneously, very easily occurs aging; Vitamin C, kojic acid are oxidizable, and the shelf-life is short; Arbutin, as plant extract, has the advantage of effect safety, be thus widely used, but the effect of restraint of tyrosinase is not strong.
Compound basis of the present invention is as follows:
Methyl cinnamate: methyl cinnamate has obvious inhibitory action to tryrosinase, can restraint of tyrosinase single phenolase vigor and and diphenol enzyme activity.There is obvious prolongation to the depression effect main manifestations of single phenolase of tryrosinase in the lag time of enzymic catalytic reaction, competitive is shown as to the inhibitory action of two phenolase and suppresses type, suppress constant (K
i) be 0. 66 mmol/L, to the relative inhibition of two phenolase reach 50% cinnamic acid first vinegar concentration (
iC 50) be 1. 49mmol/L, than daily arbutin (
iC 50)=5. 3 mmol/L) much lower.In addition, the safety of cinnamic acid first vinegar is high, and oneself is widely used in daily essence and food flavor, is a kind of tyrosinase inhibitor having very much market potential.
Cys: Cys combines enzymatic reaction product, generates colourless substance, makes tryrosinase not show activity; Cys also can reduce the stable state vigor of tryrosinase, illustrates that Cys irreversibly can combine with the active center of tryrosinase, thus inhibits the activity of tryrosinase.
Tea polyphenols: tea polyphenols is a kind of new type natural antioxidant.Under room temperature, low concentration, tea polyphenols has very strong non-oxidizability; the free radical of energy shielding of ultraviolet and removing ultraviolet induction; thus the normal function of protection melanocyte; simultaneously; tryrosinase and catalase activity in all right T suppression cell of tea polyphenols; thus reduce the peroxidation of melanic secretion and lipid, realize effect of spot-eliminating beauty treatment.
Procyanidin: procyanidin (OPC) is the polyphenol compound extracted from plant, in Semen Vitis viniferae extract, OPC content reaches as high as 95%, is the most effective Natural antioxidant of removing people interior free yl of generally acknowledging in the world, has very strong activity in vivo.Experiment proves, the free radical resisting oxidability of OPC is 50 times of vitamin E, ascorbic 20 times.Domestic and international research shows; procyanidin can resist the absorption of free radical, aging resistance, help vitamin C and vitamin E; simultaneously by catching active oxygen and regulation and control collagenase, Elastase, hyaluronic acid activity; protection vascular endothelial cell; improve microcirculation; strengthen skin elasticity and soft and smooth sense, slow down aging, beauty treatment and eliminating spot.Procyanidin or natural sunlight overcover, can shielding of ultraviolet infringement skin.Proanthocyanidin can also repair injured collagen protein and elastic fiber, meanwhile, has astriction, tightens up skin, and prevent occurring ahead of time of wrinkle of skin, life-time service can make skin smooth, high resilience, has the effect of looks improving and the skin nourishing.
Magnesium L-Asacorbic Acid 2-O-Phosphate: vitamin C and derivant vitamin C thereof are a kind of antioxidant, have whitening and speckle dispelling effect.Vitamin C is oxidizable, variable color, makes ascorbic derivant, and the effect of staying pale increases absorption and the stability of skin.As Magnesium L-Asacorbic Acid 2-O-Phosphate.Being widely used in whitening dispels in the cosmetics of class, has to freckle, chloasma, senile plaque the effect alleviated.In addition, also there is the effect promoting collagen formation and scavenging free radicals.
Vitamin E: vitamin E is antioxidant, can help to eliminate the free radical in body, prevent subcutaneous fat to be oxidized, strengthen the vigor of epiderm skin and hypodermal cell, avoid skin senilism.Also can the deposition of check melanin on skin, accelerate melanin and excrete from epidermis or through blood circulation.
Hyaluronic acid: have efficient moisture-retention function, can improve rapidly cutis laxa, promote collagen protein regeneration, stop the destruction of free radical, promote cellular energy and repair ability.Tool aging resistance, whitening fast, desalination face black speck, elimination microgroove, tender bright effect.
Radix Glycyrrhizae: sweet in the mouth, property is put down, nontoxic, treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, longue meat, times strength, removing toxic substances, and clothes are made light of one's life by commiting suicide and prolonged life for a long time.Raw by pathogenic fire purging heat, ripe use is fallen apart exterior cold, goes pharyngalgia, except pathogenic heat, and slow healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening.Radix Glycyrrhizae is in tcm prescription, apply quite general a herb, has the effect of class Corticosterone, is often used as removing toxic substances antiinflammatory.In recent years, from Radix Glycyrrhizae, propose new effective ingredient licoflavone is a kind of well whitening composition, its whitening function from it to the suppression of tryrosinase and to the active suppression of dopachrome isomerase (TRP-2) and the obstruction to the polymerization of DHICA oxidase.
Radix Angelicae Sinensis: in Radix Angelicae Sinensis containing VitAVitE, vitamin B12, containing amino acid/11 7 kinds, the inorganic elements 16 kinds containing needed by human: K, Na, Ca, Mg, P, Si, Al, Fe, Zn, Se etc.In addition when giving back containing multiple sugar as sucrose, fructose, arabinose etc.Radix Angelicae Sinensis has the effect of enriching blood and invigorating blood circulation, and QI and blood can be made to fill Sheng, and blood flow is unobstructed, has rosy cheeks, glossy, and skin is delicate, flexible.So Radix Angelicae Sinensis has the effect of nourishing blood and preserving youthful looks.Experiment finds that Radix Angelicae Sinensis is inhibited to tyrosinase activity, and has scavenging action to the oxygen-derived free radicals in human body, anti-aging effects, prevents melanin deposition.
Rhizoma Chuanxiong: nature and flavor are pungent, warm, returns liver, gallbladder, pericardium channel; Blood pressure lowering regulating menstruation, has blood-activating and qi-promoting, wind-expelling pain-stopping, calmness, blood stasis dispelling, preserves youthful looks and the effect such as to brighten.
The Rhizoma Atractylodis Macrocephalae: the Rhizoma Atractylodis Macrocephalae is inhibited and have senile-resistant efficacy to pigmentation.The Rhizoma Atractylodis Macrocephalae is the rhizome of the Compositae herbaceos perennial Rhizoma Atractylodis Macrocephalae, and bitter in the mouth is warm in nature, invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis is antiabortive, and it has certain inhibitory action to skin pathomycete.Ancient books " property of medicine opinion " claims: " dip in wine (or vinegar) with the Rhizoma Atractylodis Macrocephalae, uniform application on the face, can control freckle.”
Correspondingly, the embodiment of the present invention additionally provides a kind of QUBAN SHUANG preparation method, comprise: methyl cinnamate, vitamin E, glyceryl monostearate, octadecanol, stearic acid, liquid paraffin, white vaseline, antiseptic are mixed by weight ratio, steady temperature is within the scope of 75 DEG C ~ 80 DEG C, until stir, as oil phase;
Cys, Magnesium L-Asacorbic Acid 2-O-Phosphate, hyaluronic acid, Chinese medicine extract, tea polyphenols, procyanidin, sodium sulfite, stearic acid, glycerol are mixed by weight ratio, steady temperature is within the scope of 75 DEG C ~ 80 DEG C, until stir, as aqueous phase;
Slowly added in aqueous phase by oil phase, stir, emulsifying, then add essence, fully stir, pressurization discharging, displays 24 hours, then checks, then finished product tinning.
Preferably, form by the preparation of raw material of following weight portion:
Chinese medicine extract 20 ~ 30 parts, Cys 0.1 ~ 1 part, methyl cinnamate 0.1 ~ 1 part, Magnesium L-Asacorbic Acid 2-O-Phosphate 1 ~ 5 part, vitamin E 0.1 ~ 1 part, hyaluronic acid 0.05 ~ 0.5 part, tea polyphenols 0.2 ~ 1.3, procyanidin 0.2 ~ 1 part, glyceryl monostearate 0.4 ~ 2 part, sodium sulfite 0.1 ~ 0.3 part, octadecanol 3 ~ 6 parts, stearic acid 1 ~ 4 part, liquid paraffin 1 ~ 6 part, white vaseline 10 ~ 20 parts, glycerol 2 ~ 8 parts, antiseptic 0.1 ~ 0.2 part, distilled water 20 ~ 30 parts;
Described antiseptic is one in ethyl hydroxybenzoate, imidazolidinyl urea, potassium sorbate or combination.
Preferably, described Chinese medicine extract is the dry powder that extract that Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Chuanxiong, Bombyx Batryticatus, Radix Saposhnikoviae, Radix Angelicae Sinensis Chinese medicine water extraction method decocting in water routinely obtains concentrates rear spraying dry and obtains.
Preferably, the granularity of described dry powder is 20 ~ 80 orders.
It should be noted that, described Chinese medicine extract can buy qualified Chinese medicine extract product, detects after purchase, just can come into operation.
Preferably, described Chinese medicine extract is by weight ratio: Radix Glycyrrhizae extract 5 ~ 15 parts, Rhizoma Atractylodis Macrocephalae extract 2 ~ 3 parts, Rhizoma Chuanxiong extract 3 ~ 10 parts, Bombyx Batryticatus extract 2 ~ 3 parts, Radix Saposhnikoviae extract 1 ~ 5 part, Radix Angelicae Sinensis extract 3 ~ 8.
Be below specific embodiments of the invention:
Embodiment 1
Each component is taken by following weight portion:
Chinese medicine extract 23 parts, Cys 1 part, methyl cinnamate 0.3 part, Magnesium L-Asacorbic Acid 2-O-Phosphate 2 parts, vitamin E 0.5 part, hyaluronic acid 0.1 part, tea polyphenols 0.8, procyanidin 0.2 part, glyceryl monostearate 1.7 parts, sodium sulfite 0.3 part, octadecanol 5 parts, stearic acid 2 parts, liquid paraffin 6 parts, white vaseline 20 parts, glycerol 7 parts, ethyl hydroxybenzoate 0.1 part, distilled water 30 parts.
Wherein, Chinese medicine extract comprises: Radix Glycyrrhizae extract 11 parts, Rhizoma Atractylodis Macrocephalae extract 2 parts, Rhizoma Chuanxiong extract 4 parts, Bombyx Batryticatus extract 2 parts, Radix Saposhnikoviae extract 1 part, Radix Angelicae Sinensis extract 3.
The preparation technology of the present embodiment is:
Methyl cinnamate, vitamin E, glyceryl monostearate, octadecanol, stearic acid, liquid paraffin, white vaseline, antiseptic are mixed by weight ratio, steady temperature at 75 DEG C, until stir, as oil phase;
Cys, Magnesium L-Asacorbic Acid 2-O-Phosphate, hyaluronic acid, Chinese medicine extract, tea polyphenols, procyanidin, sodium sulfite, stearic acid, glycerol are mixed by weight ratio, steady temperature at 75 DEG C, until stir, as aqueous phase;
Slowly added in aqueous phase by oil phase, stir, emulsifying, then add essence, fully stir, pressurization discharging, displays 24 hours, then checks, then finished product tinning.
Embodiment 2
Each component is taken by following weight portion:
Chinese medicine extract 30 parts, Cys 0.6 part, methyl cinnamate 0.7 part, Magnesium L-Asacorbic Acid 2-O-Phosphate 5 parts, vitamin E 1 part, hyaluronic acid 0.4 part, tea polyphenols 1, procyanidin 0.8 part, glyceryl monostearate 1.1 parts, sodium sulfite 0.2 part, octadecanol 3 parts, stearic acid 4 parts, liquid paraffin 5 parts, white vaseline 18 parts, glycerol 5 parts, ethyl hydroxybenzoate 0.2 part, distilled water 24 parts.
Wherein, Chinese medicine extract comprises: Radix Glycyrrhizae extract 14 parts, Rhizoma Atractylodis Macrocephalae extract 3 parts, Rhizoma Chuanxiong extract 5 parts, Bombyx Batryticatus extract 2 parts, Radix Saposhnikoviae extract 2 parts, Radix Angelicae Sinensis extract 4.
The preparation technology of the present embodiment, with embodiment 1, wherein prepares the temperature constant of aqueous phase and oil phase at 76 DEG C.
Embodiment 3
Each component is taken by following weight portion:
Chinese medicine extract 26 parts, Cys 0.8 part, methyl cinnamate 1 part, Magnesium L-Asacorbic Acid 2-O-Phosphate 4 parts, vitamin E 0.8 part, hyaluronic acid 0.2 part, tea polyphenols 0.4, procyanidin 0.6 part, glyceryl monostearate 1.8 parts, sodium sulfite 0.3 part, octadecanol 6 parts, stearic acid 3 parts, liquid paraffin 4 parts, white vaseline 15 parts, glycerol 8 parts, imidazolidinyl urea 0.1 part, distilled water 28 parts.
Wherein, Chinese medicine extract comprises: Radix Glycyrrhizae extract 8 parts, Rhizoma Atractylodis Macrocephalae extract 3 parts, Rhizoma Chuanxiong extract 3 parts, Bombyx Batryticatus extract 3 parts, Radix Saposhnikoviae extract 2 parts, Radix Angelicae Sinensis extract 7.
The preparation technology of the present embodiment, with embodiment 1, wherein prepares the temperature constant of aqueous phase and oil phase at 78 DEG C.
Embodiment 4
Each component is taken by following weight portion:
Chinese medicine extract 28 parts, Cys 0.2 part, methyl cinnamate 0.4 part, Magnesium L-Asacorbic Acid 2-O-Phosphate 3 parts, vitamin E 0.2 part, hyaluronic acid 0.3 part, tea polyphenols 1.2, procyanidin 1 part, glyceryl monostearate 0.5 part, sodium sulfite 0.1 part, octadecanol 4 parts, stearic acid 4 parts, liquid paraffin 5 parts, white vaseline 19 parts, glycerol 6 parts, potassium sorbate 0.1 part, distilled water 27 parts.
Wherein, Chinese medicine extract comprises: Radix Glycyrrhizae extract 6 parts, Rhizoma Atractylodis Macrocephalae extract 2 parts, Rhizoma Chuanxiong extract 8 parts, Bombyx Batryticatus extract 2 parts, Radix Saposhnikoviae extract 4 parts, Radix Angelicae Sinensis extract 6.
The preparation technology of the present embodiment, with embodiment 1, wherein prepares the temperature constant of aqueous phase and oil phase at 80 DEG C.
Test example
Clinical trial is carried out 100 volunteers, and wherein, male 7 people, women 93 people, the range of age was at 12 ~ 50 years old.
QUBAN SHUANG of the present invention is coated on face by each volunteer, sooner or later respectively once, according to therapeutic effect, uses and observes after 3 months.Determine to use curative effect by following criterion of therapeutical effect.
Cure: facial skin is normal skin tone.
Take a turn for the better: skin lesion disappears more than 30%.
Invalid: skin lesion is without significant change or disappear less than more than 30%.
Through Clinical practice, in above-mentioned 100 test examples, take a turn for the better 89 examples, wherein cures 80 examples, invalid 11 examples.
And, treatment anteroposterior diameter is had a blood test, urine, feces are conventional and hepatic and renal function all in normal range, skin is without any stimulation and pigmentation.
In sum, implement the embodiment of the present invention, there is following beneficial effect:
The present invention adopts Chinese medicine and plant extract can the activity of effective restraint of tyrosinase, reduces melanic formation, prevents and eliminate facial melanin pigmentation, freckle effect is obvious, and nourishes rough skin, improves skin quality simultaneously, and safe and reliable, easy to use, concrete effect is as follows:
(1) plurality of Chinese and plant extract is adopted to have very strong non-oxidizability in the present invention, the free radical of energy shielding of ultraviolet and removing ultraviolet induction, thus the normal function of protection melanocyte, play sun-proof effect; Meanwhile, tryrosinase and catalase activity in all right T suppression cell, thus reduce the peroxidation of melanic secretion and lipid, prevent and eliminate facial melanin pigmentation, reaching and stop and eliminate skin splash, chloasma, freckle, realizes effect of spot-eliminating beauty treatment.
(2) the present invention can help to eliminate the free radical in body, subcutaneous fat is prevented to be oxidized, strengthen the vigor of epiderm skin and hypodermal cell, avoid skin senilism, promote that collagen is formed, the destruction of prevention collagen fiber and elastic fiber, makes skin keep due elasticity and tension force, avoids skin sagging and wrinkle to produce.
(3) solve traditional Chinese medical science interior application treatment dose large, side effect is many, internal recycle malleable in body thus unhealthful, and costly, not perseverant problem.Adopt Chinese medicine inner disease outer treat, absorb fast with YAOJING, skin, consumption is little, and effect directly, makes medicine going from the exterior into the interior desalinate whitening and disappears to mottle.
(4) usage of the present invention is simple, safe and reliable, and carry storage conveniently, medical expense is low, is applicable to all ages and classes colony and uses.
(5) the present invention is not containing corrosive medicine, and use rear without peeling, changing skin phenomenon, after curing, the colour of skin is normal, not easily recurs, preventing from scar.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.
Claims (5)
1. a QUBAN SHUANG, is characterized in that, the preparation of raw material comprising following weight portion forms:
Chinese medicine extract 20 ~ 30 parts, Cys 0.1 ~ 1 part, methyl cinnamate 0.1 ~ 1 part, Magnesium L-Asacorbic Acid 2-O-Phosphate 1 ~ 5 part, vitamin E 0.1 ~ 1 part, hyaluronic acid 0.05 ~ 0.5 part, tea polyphenols 0.2 ~ 1.3, procyanidin 0.2 ~ 1 part, glyceryl monostearate 0.4 ~ 2 part, sodium sulfite 0.1 ~ 0.3 part, octadecanol 3 ~ 6 parts, stearic acid 1 ~ 4 part, liquid paraffin 1 ~ 6 part, white vaseline 10 ~ 20 parts, glycerol 2 ~ 8 parts, antiseptic 0.1 ~ 0.2 part, distilled water 20 ~ 30 parts.
2. QUBAN SHUANG as claimed in claim 1, it is characterized in that, described Chinese medicine extract comprises: Radix Glycyrrhizae extract, Rhizoma Atractylodis Macrocephalae extract, Rhizoma Chuanxiong extract, Bombyx Batryticatus extract, Radix Saposhnikoviae extract, Radix Angelicae Sinensis extract.
3. QUBAN SHUANG as claimed in claim 2, it is characterized in that, described Chinese medicine extract is by weight ratio: Radix Glycyrrhizae extract 5 ~ 15 parts, Rhizoma Atractylodis Macrocephalae extract 2 ~ 3 parts, Rhizoma Chuanxiong extract 3 ~ 10 parts, Bombyx Batryticatus extract 2 ~ 3 parts, Radix Saposhnikoviae extract 1 ~ 5 part, Radix Angelicae Sinensis extract 3 ~ 8.
4. QUBAN SHUANG as claimed in claim 1, is characterized in that, described antiseptic is one in ethyl hydroxybenzoate, imidazolidinyl urea, potassium sorbate or combination.
5. QUBAN SHUANG as claimed in claim 1, it is characterized in that, described procyanidin is Semen Vitis viniferae extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410554289.1A CN104352400A (en) | 2014-10-20 | 2014-10-20 | Freckle removing cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410554289.1A CN104352400A (en) | 2014-10-20 | 2014-10-20 | Freckle removing cream |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104352400A true CN104352400A (en) | 2015-02-18 |
Family
ID=52519779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410554289.1A Pending CN104352400A (en) | 2014-10-20 | 2014-10-20 | Freckle removing cream |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104352400A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147559A (en) * | 2015-09-25 | 2015-12-16 | 夏放军 | Skin cream and preparing method thereof |
| CN108938851A (en) * | 2018-08-20 | 2018-12-07 | 河北东医生物科技有限公司 | Cutaneous activation element application in TCM |
| CN114652619A (en) * | 2022-05-09 | 2022-06-24 | 中国科学院烟台海岸带研究所 | Active oil-soluble anthocyanin and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1208606A (en) * | 1997-08-18 | 1999-02-24 | 陈利华 | Face-care prepn. contg. natural ingredients |
| CN101129309A (en) * | 2007-08-24 | 2008-02-27 | 杨凌无为制药有限公司 | Traditional Chinese medicine essence cream for dispelling speckle and whitening |
| KR20120026362A (en) * | 2010-09-09 | 2012-03-19 | 주식회사 이손화학 | Lactic acid bacteria composition used masksheet |
-
2014
- 2014-10-20 CN CN201410554289.1A patent/CN104352400A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1208606A (en) * | 1997-08-18 | 1999-02-24 | 陈利华 | Face-care prepn. contg. natural ingredients |
| CN101129309A (en) * | 2007-08-24 | 2008-02-27 | 杨凌无为制药有限公司 | Traditional Chinese medicine essence cream for dispelling speckle and whitening |
| KR20120026362A (en) * | 2010-09-09 | 2012-03-19 | 주식회사 이손화학 | Lactic acid bacteria composition used masksheet |
Non-Patent Citations (2)
| Title |
|---|
| 中华人民共和国卫生部: "《化妆品卫生规范》", 31 January 2007 * |
| 姬学亮: "《洗涤剂和化妆品生产技术》", 31 August 2006, 科学出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147559A (en) * | 2015-09-25 | 2015-12-16 | 夏放军 | Skin cream and preparing method thereof |
| CN108938851A (en) * | 2018-08-20 | 2018-12-07 | 河北东医生物科技有限公司 | Cutaneous activation element application in TCM |
| CN114652619A (en) * | 2022-05-09 | 2022-06-24 | 中国科学院烟台海岸带研究所 | Active oil-soluble anthocyanin and preparation method and application thereof |
| CN114652619B (en) * | 2022-05-09 | 2023-12-12 | 中国科学院烟台海岸带研究所 | Active oil-soluble anthocyanin as well as preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104644523B (en) | A kind of medical bio smoothing wrinkle suppression spot dressing and preparation method thereof | |
| CN106074206B (en) | A kind of skin care host agent, preparation method and applications | |
| CN104434618B (en) | Have whitening, nti-freckle concurrently and print nine grass green frosts of effect and preparation method thereof | |
| CN103932970A (en) | Chinese herbal medicine freckle-removal compound cosmetic and preparation method thereof | |
| CN104814908A (en) | Mask with effects of resisting wrinkle and tendering skin | |
| CN105125466A (en) | Freckle removing night cream and preparing method thereof | |
| CN108078834A (en) | It is a kind of to have effects that inhibit melanin and the composition soothed the skin and its application in cosmetics | |
| CN104825347B (en) | A kind of medical bio whitening and spot-eliminating dressing and preparation method thereof | |
| KR20100022137A (en) | Shampoo for protect from loose hair including fermented medicinal herbs extract with deer antlers and its producing method | |
| CN103976935A (en) | Anti-aging stoste and preparation method thereof | |
| CN104352400A (en) | Freckle removing cream | |
| CN106924134A (en) | A kind of Chinese medicine whitening spot-relieving cream and preparation method thereof | |
| CN108938511B (en) | Composition of natural plant extracts and application of composition in skin moisturizing and acne removing products | |
| CN106890120A (en) | A kind of Chinese medicine Whitening, spot breast and preparation method thereof | |
| WO2015010372A1 (en) | Cream used for treatment of acne hyperpigmentation spot and for whitening | |
| CN109984988A (en) | A kind of facial masks for whitening faces and removing spots | |
| CN102100658A (en) | Pawpaw coix seed facial mask | |
| CN108815015A (en) | A kind of eye mask and its production technology | |
| CN109439473B (en) | Freckle-removing beauty soap and preparation method thereof | |
| CN104352399A (en) | Preparation method for freckle removing cream | |
| CN106491477A (en) | A kind of skin care item and preparation method thereof | |
| CN108815112A (en) | Whitening spot-removing face mask of traditional Chinese medicine | |
| CN104306307A (en) | Whitening and anti-freckle traditional Chinese medicine facial mask | |
| CN109745284A (en) | A kind of essence facial mask and preparation method thereof | |
| CN109330957A (en) | White lucid ganoderma beautifying facial treatment mask and washing lotion |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150218 |