CN113081910B - Repairing composition and application thereof - Google Patents

Repairing composition and application thereof Download PDF

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Publication number
CN113081910B
CN113081910B CN202110242423.4A CN202110242423A CN113081910B CN 113081910 B CN113081910 B CN 113081910B CN 202110242423 A CN202110242423 A CN 202110242423A CN 113081910 B CN113081910 B CN 113081910B
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parts
skin
component
seed oil
repair
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CN113081910A (en
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邓伟健
刘立侠
史宝彬
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Youyan Dermatology Research Guangzhou Co ltd
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Youyan Dermatology Research Guangzhou Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides a repairing composition and application thereof, and relates to the technical field of daily cosmetics, wherein the repairing composition comprises the following components in parts by weight: 0.05-0.25 part of rhizobium japonicum gum, 1.0-3.0 parts of trehalose, 0.1-0.5 part of acid bean seed polysaccharide, 1.0-3.0 parts of winged-seed moringa seed oil, 0.8-4.0 parts of white pond flower seed oil, 0.3-1.0 parts of tocopheryl acetate, 0.272-1.7 parts of betaine, 0.0008-0.005 part of gardenia fruit extract, 0.054-0.15 part of mannose phosphate sodium, 0.054-0.15 part of mannose, 0.1-2.0 parts of nicotinamide and 0.1-0.6 part of bisabolol. The repairing composition disclosed by the invention has multiple effects of moisturizing, whitening, resisting wrinkles, resisting aging, resisting allergy, relieving the like, can effectively resist skin problems such as dry skin, aging, wrinkles, color spots, darkening skin color, allergy and the like caused by external environment stimulation, and comprehensively and effectively care skin health.

Description

Repairing composition and application thereof
Technical Field
The invention relates to the technical field of daily cosmetics, in particular to a repairing composition and application thereof.
Background
The skin serves as the largest human organ, is in contact with the external environment at any time, and is continuously stimulated from the external environment. Under the action of external environmental pollutants, invasion of microorganisms, sun illumination and other stimulus factors, skin can be sensitized to different degrees, such as skin becomes dry, itching, stinging, tense and other symptoms, and the problems of aging, wrinkles, color spots, deep complexion and the like occur, so that the skin health is seriously affected.
Along with the improvement of the living standard of people and the enhancement of the maintenance consciousness, skin health management becomes more and more important in the daily life of people, people can adopt various care and maintenance products to repair and maintain the skin, so that the skin is prevented from generating more serious skin problems under the stimulation of the external environment, the skin health is effectively cared, and the external image is improved.
Among the numerous skin care products, the repair cream is a cream product having a repair function on the skin. The moisturizing repair cream is mainly used in the market at present, has good moisturizing effect, and can keep skin moist, so that the external environment stimulation is resisted. However, when the human skin is stimulated by the external environment, the skin problems are complex and various problems are interwoven, the problem cannot be effectively solved by simply moisturizing, and the problem cannot bring comprehensive care to consumers.
Disclosure of Invention
The invention aims to provide a repairing composition and application thereof, and aims to solve the problem that the repairing product on the market at present cannot simultaneously cope with various skin problems and provide comprehensive care for the skin.
In order to achieve the above object, in a first aspect, the present invention provides a repairing composition, which comprises the following components in parts by weight: 0.05-0.25 part of rhizobium japonicum gum, 1.0-3.0 parts of trehalose, 0.1-0.5 part of acid bean seed polysaccharide, 1.0-3.0 parts of winged-seed moringa seed oil, 0.8-4.0 parts of white pond flower seed oil, 0.3-1.0 parts of tocopheryl acetate, 0.272-1.7 parts of betaine, 0.0008-0.005 part of gardenia fruit extract, 0.054-0.15 part of mannose phosphate sodium, 0.054-0.15 part of mannose, 0.1-2.0 parts of nicotinamide and 0.1-0.6 part of bisabolol.
According to the technical scheme, the rhizobia gum is natural polysaccharide prepared through biological fermentation, has a double-helix structure, can effectively lock skin moisture, and reduces transepidermal water loss; rhizobia gum is also a skin feel modifier, has unique slippery feel, and can effectively improve the sticky feel and the spreadability of the repair cream.
The trehalose has excellent moisturizing effect, can improve the capability of the skin to adapt to the environment, and can keep the skin tender; trehalose also has radioprotective effect, and has stabilizing effect on antioxidant polyphenols, and can effectively resist aging and aging.
The winged-seed moringa seed oil has the effect of deeply purifying the skin, and can soften the epidermal cells to smooth and moisten the skin, thereby improving the skin state; the winged seed moringa seed oil also has the functions of resisting oxidation and resisting aging.
The white pond flower seed oil is used as basic oil, has the effects of preventing water loss and regenerating skin, and can promote skin metabolism; the white pool seed oil also has the effects of changing keratin tissues and regulating exudation of water and compounds, and can reabsorb moisture and form hydrate in epidermal cells, so that moisture is locked in the epidermis of the skin, and light, soft and dry skin feel is given.
The tocopheryl acetate is a vitamin E derivative, has excellent antioxidant and anti-aging effects, has good moisturizing and anti-aging effects on skin, and can soften the touch feeling of the skin and keep the moisture of the skin. Tocopheryl acetate also has effects of promoting wound healing, preventing inflammation, preventing rough skin chapping, and improving black speck.
Betaine is an excellent natural moisture absorption factor, has strong moisture absorption, can provide a large amount of moisture for skin, and ensures that the skin is smooth and moist at any time; betaine also has antiallergic effect, and is protected from external factors; meanwhile, the betaine also has good osmotic pressure regulating effect, protects cell balance and increases the water content of the superficial skin.
The fructus Gardeniae extract is red brown powder extract of fruit of Gardenia jasminoides Ellis of Rubiaceae, is rich in geniposide, and has effects in relieving allergy, improving skin resistance, sterilizing, relieving inflammation, softening cutin, and tranquilizing and soothing heart.
The nicotinamide has small molecular weight, can be directly absorbed by epidermal cells, stimulates the activity of the cells which have been attenuated, promotes the synthesis of collagen, prevents melanin hyperpigmentation, and achieves the effect of whitening. After melanin is generated, only when the melanin is transported to the horny layer, the skin can be blackened, the transportation of the melanin to the horny layer of the skin can be reduced by the nicotinamide, the metabolism can be accelerated by the nicotinamide, and the horny layer containing melanocytes can be accelerated to fall off, so that the deposition of the melanin on the horny layer is reduced, and the blackening of the skin is avoided.
The repair cream disclosed by the invention has multiple effects of moisturizing, whitening, resisting wrinkles, resisting aging, resisting allergy, relieving the like, can effectively resist skin problems such as dry skin, aging, wrinkles, color spots, darkening skin color, allergy and the like caused by external environment stimulation, and comprehensively and effectively care skin health.
As a preferred embodiment of the repair composition of the present invention, the repair composition comprises the following components in parts by weight: 0.10-0.15 part of rhizobium japonicum gum, 1.0-2.0 parts of trehalose, 0.1-0.3 part of acid bean seed polysaccharide, 1.5-2.5 parts of winged-seed moringa seed oil, 1.5-2.5 parts of white pond flower seed oil, 0.3-0.5 part of tocopheryl acetate, 1.0-1.4 parts of betaine, 0.001-0.002 part of gardenia fruit extract, 0.06-0.10 part of mannose phosphate sodium, 0.06-0.10 part of mannose, 0.1-0.5 part of nicotinamide and 0.2-0.5 part of bisabolol.
As a preferred embodiment of the repair composition of the present invention, the repair composition comprises the following components in parts by weight: 0.12 part of rhizobium japonicum gum, 1.3 parts of trehalose, 0.2 part of acid bean seed polysaccharide, 2.0 parts of winged-seed moringa seed oil, 2.0 parts of white pond flower seed oil, 0.3 part of tocopheryl acetate, 1.2 parts of betaine, 0.001 part of gardenia fruit extract, 0.08 part of sodium mannose phosphate, 0.08 part of mannose, 0.3 part of nicotinamide and 0.3 part of bisabolol.
The dosage proportion of the components has great influence on the effect of the repairing composition, and a large number of experiments show that the optimal comprehensive effects of moisturizing, whitening, anti-wrinkle, anti-aging and anti-allergy relieving can be realized by adopting the component proportion.
In a second aspect, the invention also proposes the use of a restorative composition in a cosmetic product.
In a third aspect, the invention also provides a repair cream, which comprises the repair composition, and further comprises the following components in parts by weight: 1.7-5.6 parts of thickening agent, 2.9-11.5 parts of humectant, 1.8-6.0 parts of emulsifying agent, 0.4-0.9 part of preservative, 0.01-0.1 part of essence and 65-85 parts of water, wherein the preservative is phenoxyethanol. Phenoxyethanol can cause the loss of permeability of microbial membranes, so that the content of the new cells is exuded, and the energy generated by electronic power is lost, thereby achieving the anti-corrosion effect.
As a preferred embodiment of the repair cream of the present invention, the thickener comprises the following components in parts by weight: 0.2-0.6 part of sodium polyacryl dimethyl taurate, 0.5-2.0 parts of cetostearyl alcohol and 1.0-3.0 parts of cyclopenta-dimethyl siloxane.
As a preferred embodiment of the repair cream of the present invention, the humectant comprises the following components in parts by weight: 0.05-0.16 part of allantoin, 1.0-3.0 parts of jojoba seed oil, 0.2-1.0 part of D-panthenol, 1.382-4.95 parts of glycerol and 0.3-2.0 parts of butanediol.
In the technical scheme of the invention, the allantoin can keep the moisture of the skin and maintain the physiological balance in the moisture of the skin, can supplement sufficient moisture for the cell gap when peeling off metabolic cutin, and can also help the rough and chapped skin to restore to smoothness. Jojoba seed oil is not easy to oxidize, has high temperature resistance, high pressure resistance and small viscosity change, has better touch sense and ductility than other vegetable oil, has soft and elastic feel to skin, and is easy to be absorbed by skin. The allantoin, jojoba seed oil, D-panthenol, glycerol and butanediol are mixed and used as a humectant to improve the formula stability and the moisturizing effect of the repair cream product.
As a preferred embodiment of the repair cream of the present invention, the emulsifier comprises the following components in parts by weight: 1.4-3.6 parts of cetostearyl alcohol wheat straw glycosides, 0.2-0.7 part of tris (cetostearyl alcohol polyether-4) phosphate, 0.2-1.5 parts of C14-22 alcohol and 0.0004-0.0025 part of maltodextrin.
As a preferred embodiment of the repair cream of the present invention, the repair cream comprises the following components in parts by weight: 0.12 part of rhizobium japonicum gum, 1.3 parts of trehalose, 0.2 part of acid bean seed polysaccharide, 2.0 parts of winged-seed moringa seed oil, 2.0 parts of white pool flower seed oil, 0.3 part of tocopherol acetate, 1.2 parts of betaine, 0.001 part of gardenia fruit extract, 0.08 part of sodium mannosaphosphate, 0.08 part of mannose, 0.3 part of nicotinamide, 0.3 part of bisabolol, 0.35 part of polyacryl dimethyl sodium taurate, 0.1 part of allantoin, 2.0 parts of cetostearyl alcohol wheat straw glycosides, 0.3 part of tris (cetostearyl alcohol polyether-4) phosphate, 1.0 part of cetostearyl alcohol, 0.5 part of C14-22 alcohol, 2.0 parts of jojoba seed oil, 1.5 parts of cyclopentamethylene glycol, 0.5 part of D-panthenol, 2.52 parts of glycerol, 0.0015 part of maltodextrin, 1.0 part of butanediol, 0.7 part of phenoxyethanol, and 79.59 parts of essence.
In a fourth aspect, the invention also provides a preparation method of the repair cream, which comprises the following steps:
(1) Mixing water, sodium polyacryl dimethyl taurate, rhizobia gum, allantoin, trehalose and acid bean seed polysaccharide, heating to 82-85 ℃, and uniformly stirring to obtain a component A;
(2) Mixing cetostearyl alcohol wheat straw glycosides, tris (cetostearyl alcohol polyether-4) phosphate, cetostearyl alcohol, C14-22 alcohol, jojoba seed oil, moringa seed oil, white pond flower seed oil, tocopheryl acetate and cyclopentadimethicone, heating to 82-85 ℃, and uniformly stirring to obtain a component B;
(3) Adding the component B into the component A, homogenizing, preserving heat, stirring and cooling to below 38 ℃ to obtain a component C;
(4) Pre-dissolving D-panthenol with water, mixing glycerol, betaine, fructus Gardeniae extract, maltodextrin, sodium mannose phosphate, mannose and nicotinamide, adding into component C, and homogenizing to obtain component D;
(5) Mixing butanediol and phenoxyethanol, pre-dissolving, adding into the component D, and stirring uniformly to obtain a component E;
(6) Sequentially adding bisabolol and essence into the component E, and homogenizing until the components are completely dispersed to obtain the repair cream.
Compared with the prior art, the invention has the beneficial effects that:
according to the technical scheme, the prepared repairing composition has multiple effects of moisturizing, whitening, anti-wrinkle, anti-aging, anti-allergy and relieving and the like by the synergistic effect of the rhizobia gum, trehalose, acid bean polysaccharide, winged seed moringa seed oil, white pool flower seed oil and tocopheryl acetate, and can effectively resist skin problems of dry skin, aging, wrinkles, color spots, darkening skin color, allergy and the like caused by external environmental stimulation, and comprehensively and effectively care skin health.
According to the preparation method, according to the characteristics of the raw material components, the adding steps and the compatibility and mixing conditions of the components are strictly controlled, and the prepared repairing composition is applied to the production of cosmetics, and has the advantages of good stability and uniform texture dispersion.
Detailed Description
For a better description of the objects, technical solutions and advantages of the present invention, the present invention will be further described by means of specific examples.
The raw materials in the examples and comparative examples of the present invention were all purchased from the market.
The compositions of the raw materials of the repair cream of examples 1 to 5 are shown in Table 1 in percentage by weight; the compositions of the repair cream raw materials of comparative examples 1 to 6 in weight percent are shown in Table 2. The preparation method of the repair cream of the embodiment 1-5 comprises the following steps:
(1) Mixing water, sodium polyacryl dimethyl taurate, rhizobia gum, allantoin, trehalose and acid bean seed polysaccharide, heating to 82-85 ℃, and uniformly stirring to obtain a component A;
(2) Mixing cetostearyl alcohol wheat straw glycosides, tris (cetostearyl alcohol polyether-4) phosphate, cetostearyl alcohol, C14-22 alcohol, jojoba seed oil, moringa seed oil, white pond flower seed oil, tocopheryl acetate and cyclopentadimethicone, heating to 82-85 ℃, and uniformly stirring to obtain a component B;
(3) Adding the component B into the component A, homogenizing at a high speed, preserving heat, stirring and cooling to a temperature below 38 ℃ to obtain a component C, wherein the homogenizing time is 7 minutes, the homogenizing stirring speed is 2800r/min, and the preserving heat time is 6 minutes;
(4) Pre-dissolving D-panthenol with 2-3 times of water, mixing glycerol, betaine, fructus Gardeniae extract, maltodextrin, sodium mannose phosphate, mannose and nicotinamide, pre-dissolving, sequentially adding into component C, and homogenizing to obtain component D, wherein homogenizing stirring speed is 1500r/min, and homogenizing stirring time is 6 min;
(5) Mixing butanediol and phenoxyethanol, pre-dissolving, adding into the component D, and stirring uniformly to obtain a component E;
(6) Sequentially adding bisabolol and essence into the component E, and homogenizing until the components are completely dispersed to obtain the repair cream.
TABLE 1 composition of the raw materials for the cream of examples 1-5 (weight percent, total 100%)
The repair creams of comparative examples 1 to 6 were prepared in the same manner as in examples 1 to 5, with the corresponding omission of the non-added components.
TABLE 2 composition of the repair cream raw materials of comparative examples 1 to 6 (weight percent, total 100%)
The repair creams of examples 1 to 5 and comparative examples 1 to 6 were pale yellow pastes, and the pH values of the products obtained by diluting the repair creams with water at a ratio of 1:10 are shown in Table 3.
TABLE 3 pH test results of the repair creams of examples 1-5, comparative examples 1-6
Example 1 Example 2 Example 3 Example 4 Example 5 Comparative example 1
pH value of 5.2 5.0 5.5 5.6 5.3 4.9
Comparative example 2 Comparative example 3 Comparative example 4 Comparative example 5 Comparative example 6
pH value of 5.6 5.8 5.5 4.7 4.8
Effect example 1
Use Performance test of the repair creams of examples 1 to 5 and comparative examples 1 to 6
The test person: 11 female sanitation workers were employed as test volunteers, and the work environment was exposed to sun, with drier skin and darker skin tone.
Test sample: repair cream products of examples 1-5 and comparative examples 1-6.
The testing method comprises the following steps: 11 testers used the cream products of examples 1-5 and comparative examples 1-6, respectively, one cream product for each. Before each use of the corresponding test sample, the face is washed with clean water, and the corresponding test sample is used for 6 weeks, twice a day in the morning and evening. The skin moisture content, wrinkle, melanin content, skin stain, skin elasticity, etc. before and after use were measured by tracking and measuring every 2 weeks.
Wherein the moisture content of the facial skin is measured by a skin moisture measuring instrument, and the test result is represented by a set humidity measurement value (Moisture Measurement Value, MMV/%); skin wrinkles are measured using a skin image analysis system (Skin Visiometer SV 600); the melanin and color spot conditions are measured by a visual skin detector, and the display value of the detector is read; skin elasticity was measured using skin elasticity tester MPA580 from CK corporation, germany, using a revismeter RV600 probe and the rate of improvement was calculated. The results of the relevant tests are shown in tables 4-8.
(1) Improvement of skin moisture content
TABLE 4 repair cream products of examples 1-5 and comparative examples 1-6 for improvement of skin moisture content
(2) Skin wrinkle improvement
TABLE 5 improvement of skin wrinkles by the repair cream products of examples 1-5 and comparative examples 1-6
(3) Improvement of skin melanin
TABLE 6 improvement of skin melanin by the repair cream products of examples 1-5 and comparative examples 1-6
(4) Improvement of skin stain
TABLE 7 improvement of skin stain by the repair cream products of examples 1-5 and comparative examples 1-6
(5) Improvement of skin elasticity
TABLE 8 improvement of skin elasticity by the repair cream products of examples 1-5 and comparative examples 1-6
From the results of tables 4 to 8, the repair cream products of examples 1 to 5 and comparative examples 1 to 6 were tested in five dimensions of skin moisture content, wrinkle condition, melanin content, skin stain and skin elasticity, and the repair cream products of examples 1 to 5 had remarkable effects on improving skin moisture content, skin elasticity and reducing skin wrinkles, melanin and skin stain, among which the repair cream product of example 1 was the best.
Effect example 3
Evaluation of Using experience of the repair creams of examples 1 to 5 and comparative examples 1 to 6
According to the trial conditions of each volunteer on the corresponding repair cream product, the use experience evaluation of the use experience and the irritation index is carried out, the use experience is scored (10 minutes, 10 minutes full), and the summarized use experience effect is shown in table 9.
TABLE 9 evaluation of the Using Effect of the repair cream products of examples 1 to 5 and comparative examples 1 to 6
As can be seen from the results in Table 9, the cream products of examples 1 to 5, however, had a moist and moist, smooth and non-sticky feeling, effectively reduced wrinkles, significantly improved skin elasticity, an obvious skin lightening effect, and a higher degree of satisfaction to the subjects, as compared with the cream products of comparative examples 1 to 6.
Effect example 4
Test of anti-allergy soothing Effect of the repair creams of examples 1 to 5 and comparative examples 1 to 6
The test person: 55 volunteers participating in the experiment were female employees aged 25-35 years. The 55 volunteers were randomly divided into 11 groups of 5 persons each, each group of volunteers corresponding to the repair cream products of trial examples 1 to 5 and comparative examples 1 to 6, respectively, in units of groups.
Test sample: repair cream products of examples 1-5 and comparative examples 1-6.
The testing method comprises the following steps: each subject stimulated the skin on the inner side of the left arm with 6wt% capsaicin to cause skin allergy, so as to generate burning sensation, 1ml of corresponding test substances are smeared on the part stimulated by the capsaicin according to grouping conditions, feedback conditions of the subjects are respectively recorded for 10min, 30min and 60min after the test substances are smeared, and the recovery degree of the skin in different periods is judged according to the burning sensation of the feedback test parts of the subjects, wherein the recovery degree is totally divided into 4 grades, I indicates that the burning sensation completely disappears, II indicates that the light burning sensation, III indicates that the medium burning sensation, and IV indicates that the heavy burning sensation. The test results are shown in Table 10.
TABLE 10 anti-allergy relief test results (Unit: human) for the repair cream products of examples 1-5 and comparative examples 1-6
As can be seen from the results in Table 10, the cream products of examples 1 to 5 had faster and more efficient soothing action and the irritation was rapidly eliminated than the cream products of comparative examples 1 to 6.
Finally, it should be noted that the above embodiments are only for illustrating the technical solution of the present invention and not for limiting the scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the technical solution of the present invention may be modified or substituted equally without departing from the spirit and scope of the technical solution of the present invention.

Claims (8)

1. The repairing composition is characterized by comprising the following components in parts by weight: 0.12 part of rhizobium japonicum gum, 1.3 parts of trehalose, 0.2 part of acid bean seed polysaccharide, 2.0 parts of winged-seed moringa seed oil, 2.0 parts of white pond flower seed oil, 0.3 part of tocopheryl acetate, 1.2 parts of betaine, 0.001 part of gardenia fruit extract, 0.08 part of sodium mannose phosphate, 0.08 part of mannose, 0.3 part of nicotinamide and 0.3 part of bisabolol.
2. Use of the repair composition of claim 1 in cosmetics.
3. A repair cream comprising the repair composition of claim 1, further comprising the following components in parts by weight: 1.7-5.6 parts of thickening agent, 2.9-11.5 parts of humectant, 1.8-6.0 parts of emulsifying agent, 0.4-0.9 part of preservative, 0.01-0.1 part of essence and 65-85 parts of water, wherein the preservative is phenoxyethanol.
4. A repair cream according to claim 3, wherein the thickener comprises the following components in parts by weight: 0.2-0.6 part of sodium polyacryl dimethyl taurate, 0.5-2.0 parts of cetostearyl alcohol and 1.0-3.0 parts of cyclopenta-dimethyl siloxane.
5. A repair cream according to claim 3, wherein the humectant comprises the following components in parts by weight: 0.05-0.16 part of allantoin, 1.0-3.0 parts of jojoba seed oil, 0.2-1.0 part of D-panthenol, 1.382-4.95 parts of glycerol and 0.3-2.0 parts of butanediol.
6. A repair cream according to claim 3, wherein the emulsifier comprises the following components in parts by weight: 1.4-3.6 parts of cetostearyl alcohol wheat straw glycosides, 0.2-0.7 part of tris (cetostearyl alcohol polyether-4) phosphate, 0.2-1.5 parts of C14-22 alcohol and 0.0004-0.0025 part of maltodextrin.
7. A repair cream as claimed in claim 3, wherein the repair cream comprises the following components in parts by weight: the repair composition of claim 1, 0.35 part of sodium polyacryl dimethyl taurate, 0.1 part of allantoin, 2.0 parts of cetostearyl alcohol wheat straw glycosides, 0.3 part of tris (cetostearyl alcohol polyether-4) phosphate, 1.0 part of cetostearyl alcohol, 0.5 part of C14-22 alcohol, 2.0 parts of jojoba seed oil, 1.5 parts of cyclopentadimethicone, 0.5 part of D-panthenol, 2.52 parts of glycerin, 0.0015 part of maltodextrin, 1.0 part of butanediol, 0.7 part of phenoxyethanol, 0.06 part of essence and 79.59 parts of water.
8. A method of preparing a repair cream as claimed in claim 7, comprising the steps of:
(1) Mixing water, sodium polyacryl dimethyl taurate, rhizobia gum, allantoin, trehalose and acid bean seed polysaccharide, heating to 82-85 ℃, and uniformly stirring to obtain a component A;
(2) Mixing cetostearyl alcohol wheat straw glycosides, tris (cetostearyl alcohol polyether-4) phosphate, cetostearyl alcohol, C14-22 alcohol, jojoba seed oil, moringa seed oil, white pond flower seed oil, tocopheryl acetate and cyclopentadimethicone, heating to 82-85 ℃, and uniformly stirring to obtain a component B;
(3) Adding the component B into the component A, homogenizing, preserving heat, stirring and cooling to below 38 ℃ to obtain a component C;
(4) Pre-dissolving D-panthenol with water, mixing glycerol, betaine, fructus Gardeniae extract, maltodextrin, sodium mannose phosphate, mannose and nicotinamide, adding into component C, and homogenizing to obtain component D;
(5) Mixing butanediol and phenoxyethanol, pre-dissolving, adding into the component D, and stirring uniformly to obtain a component E;
(6) Sequentially adding bisabolol and essence into the component E, and homogenizing until the components are completely dispersed to obtain the repair cream.
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CN114522129B (en) * 2022-03-01 2024-04-26 广州市涵美化妆品有限公司 Moisturizing and tightening repair composition, cosmetic and preparation method
CN115624650A (en) * 2022-10-31 2023-01-20 珠海市雅莎医疗器械有限公司 Medical trehalose repair gel and preparation method thereof
CN115844748A (en) * 2022-12-16 2023-03-28 优颜皮肤科学研究(广州)有限公司 Eye composition and preparation method and application thereof
CN115813825A (en) * 2022-12-27 2023-03-21 广州研智化妆品有限公司 Composition capable of improving large pores and application of composition in cosmetics
CN116889538B (en) * 2023-08-30 2024-02-23 诺德溯源(广州)生物科技有限公司 Anti-aging composition for remodelling dermis structure, and preparation method and application thereof

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