CN110755351A - Whitening, moisturizing and repairing composition and application thereof - Google Patents
Whitening, moisturizing and repairing composition and application thereof Download PDFInfo
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- CN110755351A CN110755351A CN201911195834.1A CN201911195834A CN110755351A CN 110755351 A CN110755351 A CN 110755351A CN 201911195834 A CN201911195834 A CN 201911195834A CN 110755351 A CN110755351 A CN 110755351A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
Abstract
The invention discloses a whitening, moisturizing and repairing composition which comprises the following components: CDCX GH-05, keratolytic enzyme, 3-o-ethyl ascorbic acid, hyaline muscle, VB3Cherry plum extract, erythrose, aloe extract, sodium hyaluronate, and mung bean hairThe fermentation liquid, the plant composite anti-allergy agent and the tetrahydro-methyl pyrimidine carboxylic acid. The invention also discloses application of the whitening, moisturizing and repairing composition in preparation of cosmetics. The composition comprises six main whitening and skin brightening raw materials, three main moisturizing and hydrating raw materials and three main repairing raw materials, and twelve main core functional raw materials are matched to realize three effects of whitening, moisturizing and repairing; and the adopted raw materials have natural, safe and mild effects and do not have any irritation. The cosmetic containing the whitening, moisturizing and repairing composition has the effects of promoting skin metabolism, inhibiting activity of tyrosinase, inhibiting inflammation and ultraviolet injury, and restraining surrounding water molecules.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a whitening, moisturizing and repairing composition and application thereof.
Background
The cosmetic is a chemical industrial product or a fine chemical product which is applied to any part of the surface of a human body, such as skin, hair, nails, lips, teeth, etc., by painting, spraying or the like, and is intended to clean, maintain, beautify, modify and modify the appearance or modify the odor of the human body, etc., and maintain a good state. People who love beauty have more and more demands on cosmetics and higher requirements on the efficacy of the cosmetics along with the development of society and economy. The cosmetics on the market can achieve various effects such as whitening, acne removing, moisturizing, sun protection, repairing, freckle removing, aging resistance and the like. Although many existing cosmetics for whitening, brightening and repairing skin have one or two effects, the three effects of whitening, moisturizing and repairing cannot be achieved simultaneously, and other similar cosmetics contain many chemical substances and even substances violating the laws and regulations of cosmetics, are not beneficial to the skin and even the health of human bodies, are irritant and not mild enough. In addition, other similar products cannot comprehensively solve the three main effects in a plurality of ways and ways, and the formula matching is not comprehensive.
Disclosure of Invention
Based on the above, the invention aims to overcome the defects of the prior art and provide a whitening, moisturizing and repairing composition, which comprises six main whitening and skin-brightening raw materials, three main moisturizing and moisturizing raw materials and three main repairing raw materials, wherein twelve main core functional raw materials are matched to realize three effects of whitening, moisturizing and repairing, and the raw materials are safe and have no stimulation.
In order to achieve the purpose, the invention adopts the technical scheme that: a whitening, moisturizing and repairing composition, the composition comprisingThe components are as follows: CDCX GH-05, keratolytic enzyme, 3-o-ethyl ascorbic acid, hyaline muscle, VB3Cherry plum extract, erythrose, aloe extract, sodium hyaluronate, mung bean fermentation liquor, plant composite anti-allergy agent and tetrahydro-methyl pyrimidine carboxylic acid; the CDCX GH-05, the keratolytic enzyme, the 3-o-ethyl ascorbic acid, the hyaline muscle and the VB3The mass ratio of the cherry plum extract to the erythrose to the aloe extract to the sodium hyaluronate to the mung bean fermentation liquor to the plant composite anti-allergy agent to the tetrahydro-methyl pyrimidine carboxylic acid is 1: 0.35: 0.3: 0.2: 0.1: 0.05: 1: 0.5: 0.04: 0.05: 0.05: 0.03.
preferably, the CDCX GH-05 comprises the following components in percentage by mass: water 81.75%, niacinamide 10%, licorice (GLYCYRRHIZA URALENSIS) extract 0.5%, chitosamine 2%, mulberry (MORUS ALBA) bark extract 0.5%, apple (PYRUS MALUS) fruit extract 0.5%, CAMELLIA (CAMELLIA JAPONICA) flower extract 0.5%, tea (CAMELLIA SINENSIS) leaf extract 0.5%, madecassoside 0.1%, RHODIOLA ROSEA (rhodia ROSEA) extract 0.5%, TRICHOLOMA MATSUTAKE) extract 0.05%, ethylhexylglycerin 0.1%, and 1, 2-pentanediol 3%;
the keratolytic enzyme comprises the following components in percentage by mass: 44.8% of water, 30% of glycerol, 25% of propylene glycol and 0.2% of bacillus fermentation product;
the transparent muscle comprises the following components in percentage by mass: water 50%, butanediol 42.22% and hydrolyzed European plum (PRUNUS DOMESTICA) 7.78%;
the cherry plum extract comprises the following components in percentage by mass: butanediol 67.9%, Citrus (Citrus reticulata) pericarp extract 3% and water 29.1%;
the aloe extract comprises the following components in percentage by mass: water 85.38%, propylene glycol 5.9%, glycerin 3%, ALOE (ALOE VERA) extract 5%, sodium hyaluronate 0.02%, pricklyash peel (ZANTHOXYLUM BUNGEANUM) fruit extract 0.42%, and FORSYTHIA SUSPENSA (FORSYTHIA subspinsa) extract 0.28%;
the mung bean fermentation liquor comprises the following components in percentage by mass: 54% of water, 40% of butanediol and 6% of lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate;
the plant composite anti-allergic agent comprises the following components in percentage by mass: 62.2% of water, 30% of butylene glycol, 1% of centella asiatica (CENTELLA ASIATICA) extract, 1% of POLYGONUM CUSPIDATUM (Polygonum CUSPIDATUM) root extract, 1% of SCUTELLARIA BAICALENSIS (Scutellaria BAICALENSIS) root extract, 1% of tea (CAMELLIA SINENSIS) leaf extract, 1% of GLYCYRRHIZA GLABRA (Glycyrrhiza GLABRA) root extract, 1% of CHAMOMILLA RECUTITA (Chamomilla) flower extract, 1% of rosemary (Rosmarinus OFFICINALIS) leaf extract, 0.7% of 1, 2-hexanediol and 0.1% of ethylhexylglycerin.
The formula of the composition of the invention mainly improves and completes the skin from four aspects: (1) the keratolytic enzyme and the cherry plum extract can improve epidermis renewal, promote metabolism, and improve uneven skin color, so that the skin with melanin deposition can achieve skin whitening effect; (2) the transparent muscle reduces the scattered light area of the horny layer to improve uneven skin color of the epidermis, thereby increasing the brightness of the skin; (3) the extract of flos Camelliae Japonicae (Camellia JAPONICA) of Nicotinamide and CDCX GH-05 can inhibit melanin from transferring from melanocyte to keratinocyte to prevent melanin deposition on skin epidermis, thereby whitening skin; (4) the acetylcysteine, mulberry (Morus ALBA) bark extract, apple (PYRUS MALUS) fruit extract, tea (CAMELLIA SINENSIS) leaf extract, madecassoside, RHODIOLA ROSEA (RHODIOLA ROSEA) extract, Tricholoma MATSUTAKE (Tricholoma MATSUTAKE) extract and 3-o-ethyl ascorbic acid in CDCX GH-05 can inhibit the activity of tyrosinase, prevent the generation of melanin, and reduce the deposition of melanin, thereby achieving the effect of whitening skin. The composition can achieve a good whitening effect from inside to outside through the four main ways.
The composition of the invention is mainly used for improving and completing the skin from three aspects: (1) the mung bean fermentation liquor can inhibit the generation of interleukin which causes inflammation due to redness and inhibit cell damage caused by ultraviolet rays, thereby having certain repairing and protecting effects on skin; (2) the plant composite anti-allergic agent can reduce the generation of chemotactic neutrophilic granulocyte IL-8, has the inhibiting effect on mast cells and macrophages, and enhances the immunity of cells, thereby inhibiting inflammation and having certain repairing and protecting effects on skin; (3) the tetrahydro-methyl pyrimidine carboxylic acid can bind surrounding water molecules to form a 'complex', and the 'complex' is wrapped around cells, enzymes, proteins and other biomolecules to form a hydrated shell with the functions of protection, nourishing and stabilization, and stress factors can not damage the cells due to the existence of the hydrated shell, so that the cells are prevented from being damaged, and a certain repairing and protecting effect is achieved on the skin. The composition can achieve a good repairing effect from inside to outside through the three main ways.
The composition is compounded by three main moisturizing and hydrating raw materials, namely the erythrose, the aloe extracting solution and the sodium hyaluronate, so that a good moisturizing and hydrating effect can be achieved.
The invention also provides application of the whitening, moisturizing and repairing composition in preparation of cosmetics.
The whitening, moisturizing and repairing composition disclosed by the invention has good whitening, moisturizing and repairing effects, and can be used for preparing cosmetics with corresponding effects.
The invention also provides a whitening, moisturizing and repairing cosmetic which comprises the whitening, moisturizing and repairing composition and auxiliary materials.
Preferably, the whitening, moisturizing and repairing cosmetic comprises the following components in percentage by mass: CDCX GH-051%, keratolytic enzyme 0.35%, 3-o-ethyl ascorbic acid 0.3%, hyaline muscle 0.2%, VB30.1%, cherry plum extract 0.05%, erythrose 1%, aloe extract 0.5%, sodium hyaluronate 0.04%, mung bean fermentation broth 0.05%, plant composite anti-allergy agent 0.05%, tetrahydro-methyl pyrimidine carboxylic acid 0.03%, propylene glycol 4%, glycerin 2%, bacteriostatic agent 0.4%, p-hydroxyacetophenone 0.2%, allantoin 0.2%, nicotinamide 0.1%, PEG-40 hydrogenated castor oil 0.06%, hydroxyethyl cellulose 0.05%, glucomannan 0.05%, carbomer 0.05%, arginine 0.04%, xanthan gum 0.03%, and peppermint0.01 percent of alcohol lactate and the balance of water.
Preferably, the bacteriostatic agent comprises the following components in percentage by mass: 20% of caprylyl hydroximic acid, 10% of glyceryl caprylate and 70% of propylene glycol.
Preferably, the CDCX GH-05 comprises the following components in percentage by mass: water 81.75%, niacinamide 10%, licorice (GLYCYRRHIZA URALENSIS) extract 0.5%, chitosamine 2%, mulberry (MORUS ALBA) bark extract 0.5%, apple (PYRUS MALUS) fruit extract 0.5%, CAMELLIA (CAMELLIA JAPONICA) flower extract 0.5%, tea (CAMELLIA SINENSIS) leaf extract 0.5%, madecassoside 0.1%, RHODIOLA ROSEA (rhodia ROSEA) extract 0.5%, TRICHOLOMA MATSUTAKE) extract 0.05%, ethylhexylglycerin 0.1%, and 1, 2-pentanediol 3%;
the keratolytic enzyme comprises the following components in percentage by mass: 44.8% of water, 30% of glycerol, 25% of propylene glycol and 0.2% of bacillus fermentation product;
the transparent muscle comprises the following components in percentage by mass: water 50%, butanediol 42.22% and hydrolyzed European plum (PRUNUS DOMESTICA) 7.78%;
the cherry plum extract comprises the following components in percentage by mass: butanediol 67.9%, Citrus (Citrus reticulata) pericarp extract 3% and water 29.1%;
the aloe extract comprises the following components in percentage by mass: water 85.38%, propylene glycol 5.9%, glycerin 3%, ALOE (ALOE VERA) extract 5%, sodium hyaluronate 0.02%, pricklyash peel (ZANTHOXYLUM BUNGEANUM) fruit extract 0.42%, and FORSYTHIA SUSPENSA (FORSYTHIA subspinsa) extract 0.28%;
the mung bean fermentation liquor comprises the following components in percentage by mass: 54% of water, 40% of butanediol and 6% of lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate;
the plant composite anti-allergic agent comprises the following components in percentage by mass: 62.2% of water, 30% of butylene glycol, 1% of centella asiatica (CENTELLA ASIATICA) extract, 1% of POLYGONUM CUSPIDATUM (Polygonum CUSPIDATUM) root extract, 1% of SCUTELLARIA BAICALENSIS (Scutellaria BAICALENSIS) root extract, 1% of tea (CAMELLIA SINENSIS) leaf extract, 1% of GLYCYRRHIZA GLABRA (Glycyrrhiza GLABRA) root extract, 1% of CHAMOMILLA RECUTITA (Chamomilla) flower extract, 1% of rosemary (Rosmarinus OFFICINALIS) leaf extract, 0.7% of 1, 2-hexanediol and 0.1% of ethylhexylglycerin.
The invention also provides a preparation method of the whitening, moisturizing and repairing cosmetic, which comprises the following steps: (1) mixing water, glycerol, p-hydroxyacetophenone, allantoin, hydroxyethyl cellulose, glucomannan, carbomer, sodium hyaluronate and xanthan gum, stirring, heating to 75-85 deg.C, and stirring while maintaining the temperature until completely mixing; (2) adding arginine when the product obtained in the step (1) is cooled to 45 ℃, and uniformly stirring; (3) continuously adding CDCX GH-05 and VB3Mixing erythrose, aloe extractive solution, keratolytic enzyme, 3-O-ethyl ascorbic acid, Prunus cerasifera extract, nicotinamide, semen Phaseoli Radiati fermentation liquid, plant composite antiallergic agent, hyaline muscle and tetrahydro methylpyrimidine carboxylic acid, stirring; (4) uniformly mixing propylene glycol and a bacteriostatic agent, adding the mixture into the product obtained in the step (3), and continuously and uniformly stirring; (5) dissolving menthol lactate and PEG-40 hydrogenated castor oil, and adding into the product obtained in the step (4) to obtain the whitening, moisturizing and repairing cosmetic.
Preferably, the temperature in step (1) is raised to 80 ℃.
Compared with the prior art, the invention has the beneficial effects that: (1) the whitening and moisturizing facial mask comprises six main whitening and skin brightening raw materials, three main moisturizing and moisturizing raw materials and three main repairing raw materials, wherein twelve main core functional raw materials are matched to realize three effects of whitening, moisturizing and repairing; (2) the invention adopts natural, safe and mild functional raw materials without any irritation, and the used raw materials completely accord with national law rules of cosmetics; (3) the invention can realize whitening, moisturizing and repairing effects from inside to outside in multiple ways from multiple aspects, and has multiple effects of promoting skin metabolism, inhibiting activity of tyrosinase, inhibiting inflammation and ultraviolet injury, and restraining surrounding water molecules.
Drawings
FIG. 1 is a graph showing the effect of the skin care product of the present invention on certain leaves.
Fig. 2 is a diagram of the effect of the skin care product of the invention used in Jiangjiang.
FIG. 3 is a diagram showing the effect of using the skin care product of the present invention.
Fig. 4 is a graph showing the effect of using the skin care product of the present invention.
FIG. 5 is a diagram showing the moisturizing effect of the cosmetic of the present invention.
FIG. 6 is a graph showing the anti-inflammatory effect of the cosmetic of the present invention.
FIG. 7 is a graph showing the effect of the cosmetic of the present invention on inhibition of UV-induced cell damage.
Detailed Description
In order that the invention may be more fully understood, reference will now be made to the following description. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
Example 1
One embodiment of the whitening, moisturizing and repairing composition of the present invention comprises the following components: CDCX GH-05, keratolytic enzyme, 3-o-ethyl ascorbic acid, hyaline muscle, VB3Cherry plum extract, erythrose, aloe extract, sodium hyaluronate, mung bean fermentation liquor, plant composite anti-allergy agent and tetrahydro-methyl pyrimidine carboxylic acid; the CDCX GH-05, the keratolytic enzyme, the 3-o-ethyl ascorbic acid, the hyaline muscle and the VB3The mass ratio of the cherry plum extract to the erythrose to the aloe extract to the sodium hyaluronate to the mung bean fermentation liquor to the plant composite anti-allergy agent to the tetrahydro-methyl pyrimidine carboxylic acid is 1: 0.35: 0.3: 0.2: 0.1: 0.05: 1: 0.5: 0.04: 0.05: 0.05: 0.03.
the CDCX GH-05 comprises the following components in percentage by mass: water 81.75%, niacinamide 10%, licorice (GLYCYRRHIZA URALENSIS) extract 0.5%, chitosamine 2%, mulberry (MORUS ALBA) bark extract 0.5%, apple (PYRUS MALUS) fruit extract 0.5%, CAMELLIA (CAMELLIA JAPONICA) flower extract 0.5%, tea (CAMELLIA SINENSIS) leaf extract 0.5%, madecassoside 0.1%, RHODIOLA ROSEA (rhodia ROSEA) extract 0.5%, TRICHOLOMA MATSUTAKE) extract 0.05%, ethylhexylglycerin 0.1%, and 1, 2-pentanediol 3%;
the keratolytic enzyme comprises the following components in percentage by mass: 44.8% of water, 30% of glycerol, 25% of propylene glycol and 0.2% of bacillus fermentation product;
the transparent muscle comprises the following components in percentage by mass: water 50%, butanediol 42.22% and hydrolyzed European plum (PRUNUS DOMESTICA) 7.78%;
the cherry plum extract comprises the following components in percentage by mass: butanediol 67.9%, Citrus (Citrus reticulata) pericarp extract 3% and water 29.1%;
the aloe extract comprises the following components in percentage by mass: water 85.38%, propylene glycol 5.9%, glycerin 3%, ALOE (ALOE VERA) extract 5%, sodium hyaluronate 0.02%, pricklyash peel (ZANTHOXYLUM BUNGEANUM) fruit extract 0.42%, and FORSYTHIA SUSPENSA (FORSYTHIA subspinsa) extract 0.28%;
the mung bean fermentation liquor comprises the following components in percentage by mass: 54% of water, 40% of butanediol and 6% of lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate;
the plant composite anti-allergic agent comprises the following components in percentage by mass: 62.2% of water, 30% of butylene glycol, 1% of centella asiatica (CENTELLA ASIATICA) extract, 1% of POLYGONUM CUSPIDATUM (Polygonum CUSPIDATUM) root extract, 1% of SCUTELLARIA BAICALENSIS (Scutellaria BAICALENSIS) root extract, 1% of tea (CAMELLIA SINENSIS) leaf extract, 1% of GLYCYRRHIZA GLABRA (Glycyrrhiza GLABRA) root extract, 1% of CHAMOMILLA RECUTITA (Chamomilla) flower extract, 1% of rosemary (Rosmarinus OFFICINALIS) leaf extract, 0.7% of 1, 2-hexanediol and 0.1% of ethylhexylglycerin.
Example 2
The whitening, moisturizing and repairing cosmetic comprises the following components in percentage by mass: CDCX GH-051%, keratolytic enzyme 0.35%, 3-o-ethyl ascorbic acid 0.3%, hyaline muscle 0.2%, VB30.1%, Prunus cerasifera extract 0.05%, erythrose 1%, and Aloe extract0.5% of liquid, 0.04% of sodium hyaluronate, 0.05% of mung bean fermentation liquid, 0.05% of plant composite anti-allergy agent, 0.03% of tetrahydro-methyl pyrimidine carboxylic acid, 4% of propylene glycol, 2% of glycerol, 0.4% of bacteriostatic agent, 0.2% of p-hydroxyacetophenone, 0.2% of allantoin, 0.1% of nicotinamide, 0.06% of PEG-40 hydrogenated castor oil, 0.05% of hydroxyethyl cellulose, 0.05% of glucomannan, 0.05% of carbomer, 0.04% of arginine, 0.03% of xanthan gum and 0.01% of menthol lactate, and the balance of water.
The bacteriostatic agent comprises the following components in percentage by mass: 20% of caprylyl hydroximic acid, 10% of glyceryl caprylate and 70% of propylene glycol.
The CDCX GH-05 comprises the following components in percentage by mass: water 81.75%, niacinamide 10%, licorice (GLYCYRRHIZA URALENSIS) extract 0.5%, chitosamine 2%, Mulberry (MORUSALBA) bark extract 0.5%, apple (PYRUS MALUS) fruit extract 0.5%, CAMELLIA (CAMELLIA JAPONICA) flower extract 0.5%, tea (CAMELLIA SINENSIS) leaf extract 0.5%, madecassoside 0.1%, RHODIOLA ROSEA (rhodia ROSEA) extract 0.5%, TRICHOLOMA MATSUTAKE) extract 0.05%, ethylhexylglycerin 0.1%, and 1, 2-pentanediol 3%;
the keratolytic enzyme comprises the following components in percentage by mass: 44.8% of water, 30% of glycerol, 25% of propylene glycol and 0.2% of bacillus fermentation product;
the transparent muscle comprises the following components in percentage by mass: water 50%, butanediol 42.22% and hydrolyzed European plum (PRUNUS DOMESTICA) 7.78%;
the cherry plum extract comprises the following components in percentage by mass: butanediol 67.9%, Citrus (Citrus reticulata) pericarp extract 3% and water 29.1%;
the aloe extract comprises the following components in percentage by mass: water 85.38%, propylene glycol 5.9%, glycerin 3%, ALOE (ALOE VERA) extract 5%, sodium hyaluronate 0.02%, pricklyash peel (ZANTHOXYLUM BUNGEANUM) fruit extract 0.42%, and FORSYTHIA SUSPENSA (FORSYTHIA subspinsa) extract 0.28%;
the mung bean fermentation liquor comprises the following components in percentage by mass: 54% of water, 40% of butanediol and 6% of lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate;
the plant composite anti-allergic agent comprises the following components in percentage by mass: 62.2% of water, 30% of butylene glycol, 1% of centella asiatica (CENTELLA ASIATICA) extract, 1% of POLYGONUM CUSPIDATUM (Polygonum CUSPIDATUM) root extract, 1% of SCUTELLARIA BAICALENSIS (Scutellaria BAICALENSIS) root extract, 1% of tea (CAMELLIA SINENSIS) leaf extract, 1% of GLYCYRRHIZA GLABRA (Glycyrrhiza GLABRA) root extract, 1% of CHAMOMILLA RECUTITA (Chamomilla) flower extract, 1% of rosemary (Rosmarinus OFFICINALIS) leaf extract, 0.7% of 1, 2-hexanediol and 0.1% of ethylhexylglycerin.
The preparation method of the whitening, moisturizing and repairing cosmetic comprises the following steps: (1) mixing water, glycerol, p-hydroxyacetophenone, allantoin, hydroxyethyl cellulose, glucomannan, carbomer, sodium hyaluronate and xanthan gum, stirring, heating to 75-85 deg.C, and stirring while maintaining the temperature until completely mixing; (2) adding arginine when the product obtained in the step (1) is cooled to 45 ℃, and uniformly stirring; (3) continuously adding CDCX GH-05 and VB3Mixing erythrose, aloe extractive solution, keratolytic enzyme, 3-O-ethyl ascorbic acid, Prunus cerasifera extract, nicotinamide, semen Phaseoli Radiati fermentation liquid, plant composite antiallergic agent, hyaline muscle and tetrahydro methylpyrimidine carboxylic acid, stirring; (4) uniformly mixing propylene glycol and a bacteriostatic agent, adding the mixture into the product obtained in the step (3), and continuously and uniformly stirring; (5) dissolving menthol lactate and PEG-40 hydrogenated castor oil, and adding into the product obtained in the step (4) to obtain the whitening, moisturizing and repairing cosmetic.
Example 3
Leaf certain, female, 24 years old, dry skin. Before the cosmetic of the invention in example 2 is used, the skin is dry, the skin color is dark and dull, and a little acne marks exist. The skin moisture degree is improved after 3 days of using the cosmetic of the embodiment 2 of the invention; after the cosmetic disclosed by the embodiment 2 of the invention is used for 7 days, the skin brightness is improved, and the skin is moist and glossy; after the cosmetic disclosed by the embodiment 2 of the invention is used for 15 days, the dull complexion is obviously improved, the complexion is obviously lightened, and pores are repaired to be more delicate; after the cosmetic disclosed by the embodiment 2 of the invention is used for 30 days, the skin glossiness is improved, the acne marks are repaired and lightened, and the skin is full of water. The specific effect diagram is shown in fig. 1.
In Jiang, female, age 27, sensitive skin. The cosmetic of example 2 of the present invention had a few spots on the skin surface, and the skin was easily sensitive due to the large pores. After the cosmetic disclosed by the embodiment 2 of the invention is used for 3 days, the skin color is lightened, pores become small, and spots show fading signs; after the cosmetic disclosed by the embodiment 2 of the invention is used for 7 days, the skin glossiness is improved, the skin is more moist, and pores are repaired to be more delicate; after the cosmetic disclosed by the embodiment 2 of the invention is used for 15 days, the skin is full of moisture, becomes glossy and fine, and small spots are obviously faded; after the cosmetic disclosed by the embodiment 2 of the invention is used for 30 days, the skin glossiness is improved, the capillary lines are reduced, and the skin moisture is full. The specific effect diagram is shown in fig. 2.
Chengzhi, female, oily skin. Before the cosmetic disclosed by the embodiment 2 of the invention is used, the skin is greasy, the skin color is dark yellow, fine lines are obvious, and a few spots exist on the cheeks. After the cosmetic disclosed in the embodiment 2 of the invention is used for 3 days, the water wettability is improved, and the skin color is lightened; after 7 days of using the cosmetic disclosed by the embodiment 2 of the invention, fine lines are reduced, the skin is smoother, and the skin color is brighter; after the cosmetic disclosed by the embodiment 2 of the invention is used for 15 days, the skin color is obviously brightened, the dry lines and fine lines are reduced, and the skin becomes smoother; after the cosmetic disclosed by the embodiment 2 of the invention is used for 30 days, the dark yellow skin is improved, the speckles are obviously lightened, and the skin is moist and fine. The specific effect diagram is shown in fig. 3.
Yellow certain, male, 28 years old, mixed skin type. Before the cosmetic disclosed by the embodiment 2 of the invention is used, the T area is greasy, the cheek skin is lack of moisture, and partial fine wrinkles appear. After the cosmetic disclosed in the embodiment 2 of the invention is used for 3 days, the skin of the cheek becomes moist, and the skin color is brightened; after the cosmetic disclosed by the embodiment 2 of the invention is used for 7 days, fine lines are reduced, pores are finer and finer, and the skin color is obviously brightened; after the cosmetic disclosed by the embodiment 2 of the invention is used for 15 days, fine lines become light obviously, the skin color is more uniform and bright, and the water wettability is full; after the cosmetic disclosed by the embodiment 2 of the invention is used for 30 days, the skin glossiness is improved, small spots are obviously lightened, and the skin is fine and smooth. The specific effect diagram is shown in fig. 4.
Example 4 moisturizing and hydrating effects of the cosmetic composition of the present invention
5 testers with neutral to dry skin are selected, and the whitening, moisturizing and repairing cosmetic is smeared on the forearm of each tester for 12 days and 2 times a day. The moisture content of the skin was measured from day 8 to day 12, and from day 12, the application of the whitening, moisturizing and repairing cosmetic of the present invention was stopped for 7 days, and the moisture content of the skin was measured again on day 19. The results are shown in fig. 5, the whitening, moisturizing and repairing cosmetic has good moisturizing and hydrating effects, the moisture content of the skin is still high on the 7 th day after the use is stopped, and the long-term moisturizing and hydrating can be maintained for 7 days.
Example 5 anti-inflammatory repair Effect of the cosmetic according to the invention
The interleukin IL-1 β and tumor necrosis factor TNF- α released by cells are main proinflammatory cytokines for inducing inflammatory response, in the embodiment, the whitening, moisturizing and repairing cosmetic is applied to the skin wound of a mouse, and the expression of the interleukin during wound healing is observed.
Example 6 skin care products of the invention inhibit UV-induced cell damage
Pretreating human epidermal keratinocyte (HaCaT) with semen Phaseoli Radiati fermentation liquid for 6 hr at 60mJ/cm2The cells are irradiated at a dose of (a) and the amount of IL-6 and IL-8 produced by the cells are compared. The results show that: the mung bean fermentation liquor can inhibit the generation of interleukin which causes inflammation due to redness and inhibit cell damage caused by ultraviolet rays, thereby having certain repairing and protecting effects on skin. As shown in FIG. 7, the fermented mung bean liquid can inhibit the production of IL-6 and IL-8, protect cells, and prevent cell death caused by UVB.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (9)
1. A whitening, moisturizing and repairing composition, which is characterized by comprising the following components: CDCX GH-05, keratolytic enzyme, 3-o-ethyl ascorbic acid, hyaline muscle, VB3Cherry plum extract, erythrose, aloe extract, sodium hyaluronate, mung bean fermentation liquor, plant composite anti-allergy agent and tetrahydro-methyl pyrimidine carboxylic acid; the CDCX GH-05, the keratolytic enzyme, the 3-o-ethyl ascorbic acid, the hyaline muscle and the VB3The mass ratio of the cherry plum extract to the erythrose to the aloe extract to the sodium hyaluronate to the mung bean fermentation liquor to the plant composite anti-allergy agent to the tetrahydro-methyl pyrimidine carboxylic acid is 1: 0.35: 0.3: 0.2: 0.1: 0.05: 1: 0.5: 0.04: 0.05: 0.05: 0.03.
2. the whitening and moisturizing repair composition of claim 1, wherein the CDCX GH-05 comprises the following components in percentage by mass: 81.75% of water, 10% of niacinamide, 0.5% of licorice (GLYCYRRHIZA URALENSIS) extract, 2% of acetylcysteine, 0.5% of mulberry (MORUS ALBA) bark extract, 0.5% of apple (PYRUS MALUS) fruit extract, 0.5% of CAMELLIA (CAMELLIA JAPONICA) flower extract, 0.5% of tea (CAMELLIA SINENSIS) leaf extract, 0.1% of madecassoside, 0.5% of RHODIOLA ROSEA (rhoea) extract, 0.05% of tricholoma matsutake (TRICHOLOMAMATSUTAKE) extract, 0.1% of ethylhexyl glycerin and 3% of 1, 2-pentanediol;
the keratolytic enzyme comprises the following components in percentage by mass: 44.8% of water, 30% of glycerol, 25% of propylene glycol and 0.2% of bacillus fermentation product;
the transparent muscle comprises the following components in percentage by mass: water 50%, butanediol 42.22% and hydrolyzed European Plum (PRUNUSDOMESTICA) 7.78%;
the cherry plum extract comprises the following components in percentage by mass: butanediol 67.9%, Citrus (Citrus reticulata) pericarp extract 3% and water 29.1%;
the aloe extract comprises the following components in percentage by mass: water 85.38%, propylene glycol 5.9%, glycerin 3%, ALOE (ALOE VERA) extract 5%, sodium hyaluronate 0.02%, pricklyash peel (ZANTHOXYLUM BUNGEANUM) fruit extract 0.42%, and FORSYTHIA SUSPENSA (FORSYTHIA subspinsa) extract 0.28%;
the mung bean fermentation liquor comprises the following components in percentage by mass: 54% of water, 40% of butanediol and 6% of lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate;
the plant composite anti-allergic agent comprises the following components in percentage by mass: 62.2% of water, 30% of butylene glycol, 1% of centella asiatica (CENTELLA ASIATICA) extract, 1% of POLYGONUM CUSPIDATUM (Polygonum CUSPIDATUM) root extract, 1% of SCUTELLARIA BAICALENSIS (Scutellaria BAICALENSIS) root extract, 1% of tea (CAMELLIA SINENSIS) leaf extract, 1% of GLYCYRRHIZA GLABRA (Glycyrrhiza GLABRA) root extract, 1% of CHAMOMILLA RECUTITA (Chamomilla) flower extract, 1% of rosemary (Rosmarinus OFFICINALIS) leaf extract, 0.7% of 1, 2-hexanediol and 0.1% of ethylhexylglycerin.
3. Use of the whitening and moisturizing repair composition according to claim 1 or 2 in the preparation of cosmetics.
4. A whitening, moisturizing and repairing cosmetic comprising the whitening, moisturizing and repairing composition of claim 1 or 2 and an auxiliary material.
5. The whitening, moisturizing and repairing cosmetic as claimed in claim 4, wherein the cosmetic comprises the following components in percentage by mass: CDCX GH-051%, keratolytic enzyme 0.35%, 3-o-ethyl ascorbic acid 0.3%, hyaline muscle 0.2%, VB30.1 percent, 0.05 percent of cherry plum extract, 1 percent of erythrose, 0.5 percent of aloe extract, 0.04 percent of sodium hyaluronate, 0.05 percent of mung bean fermentation liquor, 0.05 percent of plant composite anti-allergy agent, 0.03 percent of tetrahydro-methyl pyrimidine carboxylic acid, 4 percent of propylene glycol, 2 percent of glycerol, 0.4 percent of bacteriostatic agent, 0.2 percent of p-hydroxyacetophenone, 0.2 percent of allantoin, 0.1 percent of nicotinamide and 0.06 percent of PEG-40 hydrogenated castor oil0.05% of hydroxyethyl cellulose, 0.05% of glucomannan, 0.05% of carbomer, 0.04% of arginine, 0.03% of xanthan gum and 0.01% of menthol lactate, and the balance of water.
6. The whitening, moisturizing and repairing cosmetic of claim 5, wherein the bacteriostatic agent comprises the following components in percentage by mass: 20% of caprylyl hydroximic acid, 10% of glyceryl caprylate and 70% of propylene glycol.
7. The whitening, moisturizing and repairing cosmetic of claim 5, wherein the CDCX GH-05 comprises the following components in percentage by mass: 81.75% of water, 10% of niacinamide, 0.5% of licorice (GLYCYRRHIZA URALENSIS) extract, 2% of acetylcysteine, 0.5% of mulberry (MORUS ALBA) bark extract, 0.5% of apple (PYRUS MALUS) fruit extract, 0.5% of CAMELLIA (CAMELLIA JAPONICA) flower extract, 0.5% of tea (CAMELLIA SINENSIS) leaf extract, 0.1% of madecassoside, 0.5% of RHODIOLA ROSEA (rhoea) extract, 0.05% of tricholoma matsutake (TRICHOLOMAMATSUTAKE) extract, 0.1% of ethylhexyl glycerin and 3% of 1, 2-pentanediol;
the keratolytic enzyme comprises the following components in percentage by mass: 44.8% of water, 30% of glycerol, 25% of propylene glycol and 0.2% of bacillus fermentation product;
the transparent muscle comprises the following components in percentage by mass: water 50%, butanediol 42.22% and hydrolyzed European Plum (PRUNUSDOMESTICA) 7.78%;
the cherry plum extract comprises the following components in percentage by mass: butanediol 67.9%, Citrus (Citrus reticulata) pericarp extract 3% and water 29.1%;
the aloe extract comprises the following components in percentage by mass: water 85.38%, propylene glycol 5.9%, glycerin 3%, ALOE (ALOE VERA) extract 5%, sodium hyaluronate 0.02%, pricklyash peel (ZANTHOXYLUM BUNGEANUM) fruit extract 0.42%, and FORSYTHIA SUSPENSA (FORSYTHIA subspinsa) extract 0.28%;
the mung bean fermentation liquor comprises the following components in percentage by mass: 54% of water, 40% of butanediol and 6% of lactobacillus/mung bean (Phaseolus RADIATUS) seed extract/sodium glutamate fermentation product filtrate;
the plant composite anti-allergic agent comprises the following components in percentage by mass: 62.2% of water, 30% of butylene glycol, 1% of centella asiatica (CENTELLA ASIATICA) extract, 1% of POLYGONUM CUSPIDATUM (Polygonum CUSPIDATUM) root extract, 1% of SCUTELLARIA BAICALENSIS (Scutellaria BAICALENSIS) root extract, 1% of tea (CAMELLIA SINENSIS) leaf extract, 1% of GLYCYRRHIZA GLABRA (Glycyrrhiza GLABRA) root extract, 1% of CHAMOMILLA RECUTITA (Chamomilla) flower extract, 1% of rosemary (Rosmarinus OFFICINALIS) leaf extract, 0.7% of 1, 2-hexanediol and 0.1% of ethylhexylglycerin.
8. The preparation method of the whitening, moisturizing and repairing cosmetic as claimed in any one of claims 5 to 7, comprising the following steps: (1) mixing water, glycerol, p-hydroxyacetophenone, allantoin, hydroxyethyl cellulose, glucomannan, carbomer, sodium hyaluronate and xanthan gum, stirring, heating to 75-85 deg.C, and stirring while maintaining the temperature until completely mixing; (2) adding arginine when the product obtained in the step (1) is cooled to 45 ℃, and uniformly stirring; (3) continuously adding CDCX GH-05 and VB3Mixing erythrose, aloe extractive solution, keratolytic enzyme, 3-O-ethyl ascorbic acid, Prunus cerasifera extract, nicotinamide, semen Phaseoli Radiati fermentation liquid, plant composite antiallergic agent, hyaline muscle and tetrahydro methylpyrimidine carboxylic acid, stirring; (4) uniformly mixing propylene glycol and a bacteriostatic agent, adding the mixture into the product obtained in the step (3), and continuously and uniformly stirring; (5) dissolving menthol lactate and PEG-40 hydrogenated castor oil, and adding into the product obtained in the step (4) to obtain the whitening, moisturizing and repairing cosmetic.
9. The method for preparing a whitening, moisturizing and repairing cosmetic as claimed in claim 8, wherein the temperature is raised to 80 ℃ in the step (1).
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| CN111728886A (en) * | 2020-07-13 | 2020-10-02 | 植物医生(广东)生物科技有限公司 | Whitening composition and preparation method and application thereof |
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