CN104173251B - A kind of bone glue of yak former peptide cleawhite pack and preparation method thereof - Google Patents
A kind of bone glue of yak former peptide cleawhite pack and preparation method thereof Download PDFInfo
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- CN104173251B CN104173251B CN201410466323.XA CN201410466323A CN104173251B CN 104173251 B CN104173251 B CN 104173251B CN 201410466323 A CN201410466323 A CN 201410466323A CN 104173251 B CN104173251 B CN 104173251B
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Abstract
The invention provides a kind of bone glue of yak former peptide cleawhite pack and preparation method thereof, calculate by weight/mass percentage composition, formula includes following components：Os Bovis grunniens collagen small peptide 3 8%；Nonanedioyl Diglycocol potassium 2 8%；Radix Sophorae Flavescentiss root extract 3 8%；Glycyrrhiza inflata Bat. root extract 2 6%；Radix Scutellariae root extract 1 4%；Hyaluronate sodium 0.03 0.07%；Glycyrrhizic acid dipotassium 0.2 0.8%；Acetyl group hexapeptide 80.004 0.008%.The present invention acts on skin of face deep layer, promotes skin microcirculation, moist moisturizing, has significant whitening, a smoothing wrinkle, and effect of slowing down skin aging can be used as facial film class skin care item life-time service.
Description
Technical field
The present invention relates to household chemicals field, particularly to a kind of cleawhite pack containing Os Bovis grunniens collagen small peptide.
Background technology
A lot of women with advancing age, operating pressure increase, the reason such as environmental pollution and computer radiate, skin becomes
Obtain coarse and intense darkness without light, the beauty mask class product with the effects such as whitening, moisturizing, wrinkle removing based on convenient and swift obtains
The favor of numerous women that like to be beautiful.
In the basal layer of epidermis iuntercellular of people, it is dispersed with melanocyte, the tryrosinase that it contains can be by tyrosine oxygen
Chemical conversion polysaccharide, centre through a series of metabolic process, finally just can generate melanin again.Melanin generation is more, and skin is just
Pitch-darker；Conversely, then skin is more pale.So, skin Bai Bubai, depend primarily on the energy of melanocyte synthesis of melanin
Power.
Tryrosinase has the dual catalytic function of uniqueness, is the key enzyme of biological internal B16 cell, with declining of people
Always there is substantial connection.Its abnormal overexpression may result in the pigmentation disease of human body.Tyrosinase inhibitor can be treated
Chromatopathy common at present such as freckle, chloasma, senile plaque.Folium Vaccinii vitis-idaeae in popular skin-lightening cosmetic on market
Chinese medicine extract such as glycosides, Radix Glycyrrhizae extract etc. are tyrosinase inhibitor, mainly by the activity of suppression tryrosinase
Reach suppression B16 cell, and then play skin whitening effect.
Collagen peptide is the novel active composition introducing in health care, beauty treatment fields in recent years, by-(Gly-Pro-Y) n-
18 kinds of aminoacid composition that basic structure is constituted, wherein X is proline, and Y is hydroxyproline, hydroxylysine and other aminoacid.
Because collagen peptide derives from biological tissue's albumen, it is to build one of living organism structural component, there is non-immunogenicity and parent
And property, so it is considered as safe and reliable biological raw material by people.Skeleton aging, formation of wrinkle of skin etc. all with its institute
Physics containing collagen or physiological reason and much relations cannot have been repaired in time.If human collagen can be supplemented in time,
Its vigor of again renewing one's youth can be made, eliminate wrinkle of skin or the generation delaying wrinkle, so that skin is full of gloss and be rich in bullet
Property.Because collagen is rich in the hydrophilic amino acid such as glycine, proline, hydroxyproline, lysine, hydroxylysine, so it is many
Peptide shows excellent hydrophilic, cannot be only used for health food, is alternatively arranged as natural water-absorbing-retaining composition, is cosmetics
Good raw material.
Os Bovis grunniens collagen small peptide is with Os Bovis grunniens collagen protein as raw material, processes through protease hydrolysiss,
The molecular weight peptides more much smaller than collagen protein, the small peptide mass fraction that its middle-molecular-weihydroxyethyl is less than below 1000 dalton is 85%
Left and right.Os Bovis grunniens collagen small peptide is soluble in water, is more easy to quickly be absorbed by human body, need not digest human body cell group of can going directly
Knit, have functions that to stay pale with the cosmetics that it is prepared, moisture of skin, slow down aging.Research has shown that, molecular weight is 1000
The following small peptide collagen protein big with respect to molecular weight, has the ability of obvious suppression tyrosinase activity and removes hydroxyl
Free radical (OH) and superoxide anion (O2 -) activity ability, to skin, there is whitening function.
Os Bovis grunniens collagen small peptide can supplement rapidly the collagen protein of skin, keeps moisture of skin, so that skin is rich in
Elasticity；Nonanedioyl Diglycocol potassium and 3-O- ethylascorbyl ether, the activity of competitive inhibition tryrosinase, have whitening and dispel
Speckle acts on；Hyaluronate sodium, glycerol, propylene glycol, butanediol have moisture-keeping functions, and wherein hyaluronate sodium has very strong holding
The function of moisture of skin；Argireline is a kind of hexapeptide of synthesis, has very strong wrinkle removing function；Pantothenylol has promotion skin
The normal keratinization of skin, promotes effect of wound healing and skin tissue recovering；Glycyrrhizic acid dipotassium, Radix Sophorae Flavescentiss root extract, Glycyrrhiza inflata Bat.
Root extract, Radix Scutellariae root extract have very strong have antibacterial, antiallergic and anti-inflammatory etc. and act on；Propylene glycol/bis- (hydroxyl first
Base) imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, methyl hydroxybenzoate there is very strong Antimicrobial preservative effect it is ensured that product not
Putrid and deteriorated；Xanthan gum, glyceryl acrylate/acrylic copolymer/propylene glycol/Gantrez AN-119 are thickening agent it is ensured that producing
The suitable viscosity of product.The bone glue of yak former peptide cleawhite pack being made up of above-mentioned raw materials, uses after tested, has obvious U.S.
Light speckle in vain, moisturizing wrinkle removing, significantly can increase skin elasticity, make skin fine and smooth, smooth, glossy.Meanwhile, product passed through
Quick grade tests confirmation, and product safety is reliable, without any side effects.
Content of the invention
It is an object of the invention to provide a kind of utilization Os Bovis grunniens collagen small peptide promotes skin absorption collagen peptide
The formula of whitening, moisturizing and anti-aging cosmetics and production technology, the present invention acts on skin of face deep layer, promotes skin
Microcirculation, nourishes moisturizing, has significant whitening, smoothing wrinkle, effect of slowing down skin aging.
For reaching above-mentioned technical purpose, this invention takes technical scheme below：A kind of bone glue of yak former peptide cleawhite pack
And preparation method thereof, its formula consists of the following composition：
Component ratio by weight：
Wherein Os Bovis grunniens collagen small peptide can reach skin corium through horny layer and epidermis rapidly, supplements the glue of skin
Former albumen, has the obvious ability suppressing tyrosinase activity simultaneously, has whitening function to skin.
Nonanedioyl Diglycocol potassium and 3-O- ethylascorbyl ether belong to functional component, can be with competitive inhibition tyrosine
The activity of enzyme, has whitening and speckle dispelling effect.
Hyaluronate sodium, glycerol, propylene glycol, butanediol have moisture-keeping functions, and wherein hyaluronate sodium has very strong guarantor
Hold the function of moisture of skin.
Glycyrrhizic acid dipotassium, Radix Sophorae Flavescentiss root extract, Glycyrrhiza inflata Bat. root extract, Radix Scutellariae root extract have very strong antibacterial,
Antiallergic and anti-inflammatory etc. act on.
Propylene glycol/Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, methyl hydroxybenzoate have very strong resisting
Bacterium antisepsises are not it is ensured that product is putrid and deteriorated.
Xanthan gum, glyceryl acrylate/acrylic copolymer/propylene glycol/Gantrez AN-119 are thickening agent it is ensured that product
Suitable viscosity.
Pantothenylol has the promotion normal keratinization of skin, promotes effect of wound healing and skin tissue recovering.
Argireline is a kind of hexapeptide of synthesis, has very strong wrinkle removing function.
Deionized water is cosmetics main matrix, plays diluting effect.
A kind of preparation method of present invention bone glue of yak former peptide cleawhite pack, comprises the following steps：
1st, the preparation of Os Bovis grunniens collagen small peptide：With fresh yak bone as raw material, high temperature steaming extracts collagen protein, presses
0.25-1% according to collagen protein total amount adds alkaline protease and neutral protease successively, digests 4 hours at 60 DEG C, enzymolysis solution
Collagen small peptide solution is obtained through membrane filtration, Os Bovis grunniens collagen small peptide powder is obtained by concentrating, being spray-dried, wherein divides
Son amount is 85% about less than the small peptide mass fraction below 1000 dalton.
2nd, Radix Sophorae Flavescentiss root extract, Glycyrrhiza inflata Bat. root extract, Radix Scutellariae root extract are added to going of 8 times of raw material gross weight
In ionized water, heated and boiled 30 minutes, filtrate is collected by filtration, when concentrating filtrate to 20 DEG C, relative density is 1.26.Will
Xanthan gum, glyceryl acrylate/acrylic copolymer/propylene glycol/Gantrez AN-119 are dissolved in deionized water, in 80 DEG C of water
Constant temperature 30min in bath thermostat, stirring is cooled to 65 DEG C, is subsequently adding filtrate and Os Bovis grunniens collagen small peptide powder, thoroughly
Bright matter acid sodium, glycyrrhizic acid dipotassium, glycerol, propylene glycol, butanediol mix homogeneously, holding 25min about, add nonanedioyl two afterwards
Glycine potassium, 3-O- ethylascorbyl ether, pantothenylol and Argireline, continue stirring to be cooled to temperature is 48 DEG C of additions
Propylene glycol/Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, methyl hydroxybenzoate, treat that temperature is cooled to 20 DEG C and adds
Enter remaining deionized water, the relative density adjusting viscous liquid is 1.15-1.2.
3rd, the viscous liquid of above-mentioned gained is adopted ultraviolet disinfection, sterilization time is 30-60 minute, subpackage is afterwards
Obtain bone glue of yak former peptide cleawhite pack.
The remarkable efficacy of the present invention is：Can be with whitening and speckle dispelling, wrinkle removing is crease-resistant, increases skin elasticity, makes skin exquisiteness, light
Sliding, glossy, without any side effects, safe and reliable, can use as everyday skincare.
Compared with prior art, the advantage of patent of the present invention：
1st, the main component of cleawhite pack of the present invention is Os Bovis grunniens collagen small peptide, from the free of contamination yak in plateau
Bone, through complex enzyme hydrolysis, molecular weight is less, can directly supplement collagen protein needed for skin, has obvious suppression cheese simultaneously
The ability of propylhomoserin enzymatic activity, has whitening function to skin.
2nd, the present invention adds the several kinds of Chinese medicinal materials such as Radix Sophorae Flavescentiss root extract, Glycyrrhiza inflata Bat. root extract, Radix Scutellariae root extract and carries
Take composition, more natural, safer.
Specific embodiment
With reference to embodiment 1-5, the present invention will be further described：
The formula of the bone glue of yak former peptide cleawhite pack of embodiment see table shown in 1：
Table 1 formula table (based on weight/mass percentage composition)
The bone glue of yak former peptide cleawhite pack of embodiment 1-5 is prepared as follows technique preparation：
1st, the preparation of Os Bovis grunniens collagen small peptide：With fresh yak bone as raw material, high temperature steaming extracts collagen protein, presses
0.25-1% according to collagen protein total amount adds alkaline protease and neutral protease successively, digests 4 hours at 60 DEG C, enzymolysis solution
Through membrane filtration be obtained collagen small peptide solution, by concentrate, be spray-dried be obtained Os Bovis grunniens collagen small peptide powder, wherein its
The small peptide mass fraction that middle-molecular-weihydroxyethyl is less than below 1000 dalton is 85% about.
2nd, Radix Sophorae Flavescentiss root extract, Glycyrrhiza inflata Bat. root extract, Radix Scutellariae root extract are added to going of 8 times of raw material gross weight
In ionized water, heated and boiled 30 minutes, filtrate is collected by filtration, when concentrating filtrate to 20 DEG C, relative density is 1.26.Will
Xanthan gum, glyceryl acrylate/acrylic copolymer/propylene glycol/Gantrez AN-119 are dissolved in deionized water, in 80 DEG C of water
Constant temperature 30min in bath thermostat, stirring is cooled to 65 DEG C, is subsequently adding filtrate and Os Bovis grunniens collagen small peptide powder, thoroughly
Bright matter acid sodium, glycyrrhizic acid dipotassium, glycerol, propylene glycol, butanediol mix homogeneously, holding 25min about, add nonanedioyl two afterwards
Glycine potassium, 3-O- ethylascorbyl ether, pantothenylol and Argireline, continue stirring to be cooled to temperature is 48 DEG C of additions
Propylene glycol/Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, methyl hydroxybenzoate, treat that temperature is cooled to 20 DEG C and adds
Enter remaining deionized water, the relative density adjusting viscous liquid is 1.15-1.2.
3rd, the viscous liquid of above-mentioned gained is adopted ultraviolet disinfection, sterilization time is 30-60 minute, subpackage is afterwards
Obtain bone glue of yak former peptide cleawhite pack.
Product beta test result：
Object on probation：Each embodiment preparation facial film try out subject age be 25-45 year, the colour of skin is more black or obscure
Women 60.
Trial method：Usage cycles 30 days, every two days using once.
Using effect see table 2：
Table 2 using effect (number)
After on probation, all do not find zest and allergic phenomena.
Claims (1)
1. a kind of preparation method of bone glue of yak former peptide cleawhite pack is it is characterised in that each component of the formula of described cleawhite pack
It is calculated as with weight/mass percentage composition：
Os Bovis grunniens collagen small peptide 3-8%
Nonanedioyl Diglycocol potassium 2-8%
Pantothenylol 1-3%
Glycerol 2-5%
Propylene glycol 2-5%
Butanediol 1-4%
Radix Sophorae Flavescentiss root extract 3-8%
Glycyrrhiza inflata Bat. root extract 2-6%
Radix Scutellariae root extract 1-4%
3-O- ethylascorbyl ether 0.5-2.0%
Xanthan gum 0.1-0.2%
Hyaluronate sodium 0.03-0.07%
Glycyrrhizic acid dipotassium 0.2-0.8%
Methyl hydroxybenzoate 0.04-0.08%
Argireline 0.004-0.008%
Propylene glycol/Bis(hydroxymethyl)imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate 0.02-0.06%
Glyceryl acrylate/acrylic copolymer/propylene glycol/Gantrez AN-119 0.15-0.25%
Deionized water surplus；Preparation technology is：
(1), the preparation of Os Bovis grunniens collagen small peptide：With fresh yak bone as raw material, high temperature steaming extracts collagen protein, according to
The 0.25-1% of collagen protein total amount adds alkaline protease and neutral protease successively, digests 4 hours at 60 DEG C, enzymolysis solution warp
Membrane filtration is obtained collagen small peptide solution, Os Bovis grunniens collagen small peptide powder, wherein molecule is obtained by concentrating, being spray-dried
Amount is 85% less than the small peptide mass fraction of 1000 dalton；
(2), by Radix Sophorae Flavescentiss root extract, Glycyrrhiza inflata Bat. root extract, Radix Scutellariae root extract be added to 8 times of raw material gross weight go from
In sub- water, heated and boiled 30 minutes, filtrate is collected by filtration, when concentrating filtrate to 20 DEG C, relative density is 1.26, by Huang
Virgin rubber, glyceryl acrylate/acrylic copolymer/propylene glycol/Gantrez AN-119 are dissolved in deionized water, in 80 DEG C of water-baths
Constant temperature 30min in thermostat, stirring is cooled to 65 DEG C, is subsequently adding filtrate and Os Bovis grunniens collagen small peptide powder, hyaluronic acid
Sodium, glycyrrhizic acid dipotassium, glycerol, propylene glycol, butanediol mix homogeneously, keep 25min, afterwards add nonanedioyl Diglycocol potassium,
3-O- ethylascorbyl ether, pantothenylol and Argireline, continue stirring be cooled to temperature be 48 DEG C add propylene glycol/bis-
(methylol) imidazolidinyl urea/iodine propilolic alcohol butyl mephenesin Carbamate, methyl hydroxybenzoate, treat temperature be cooled to 20 DEG C add residues go from
Sub- water, the relative density adjusting viscous liquid is 1.15-1.2；
(3), the viscous liquid of above-mentioned gained is adopted ultraviolet disinfection, sterilization time is 30-60 minute, subpackage obtains final product afterwards
To bone glue of yak former peptide cleawhite pack.
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| CN105380865B (en) * | 2015-12-16 | 2018-08-17 | 广州市中通生化制品有限公司 | A kind of lightening compositions and preparation method thereof containing Chinese herbal medicine extract |
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| CN106214601A (en) * | 2016-08-10 | 2016-12-14 | 西宁琉璃王生物科技有限公司 | For making compositions of emulsion containing yak milk composition and preparation method thereof |
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| CN107982162A (en) * | 2018-01-17 | 2018-05-04 | 李福禄 | A kind of facial mask essence formula |
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| CN111995671B (en) * | 2020-09-07 | 2023-06-20 | 青海瑞肽生物科技有限公司 | Collagen peptide and application thereof |
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| CN113201222B (en) * | 2021-05-24 | 2022-08-19 | 中国科学院西北高原生物研究所 | Yak skin gel/PMVE-MA composite material and preparation method and application thereof |
| CN113234140A (en) * | 2021-05-24 | 2021-08-10 | 湖南康琪壹佰生物科技有限公司 | Food for improving skin moisture and preparation method thereof |
| CN115487129A (en) * | 2021-12-07 | 2022-12-20 | 上海聚才谷新能源科技有限公司 | Conyza Glutinosa sheep placenta essence beautifying and skin beautifying cream and preparation method and application thereof |
| CN115517999B (en) * | 2022-10-26 | 2023-09-15 | 广州艾卓生物科技股份有限公司 | Anti-aging composition and application thereof in beauty and skin care |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417464A (en) * | 2013-08-09 | 2013-12-04 | 广州市博卡利生物科技有限公司 | Regeneration-type CO2 repair mask and manufacturing method thereof |
| CN103783254A (en) * | 2013-07-02 | 2014-05-14 | 吴长海 | Preparation method of yak bone collagen peptide |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6049162B2 (en) * | 2011-11-17 | 2016-12-21 | 株式会社キコーコーポレーション | Skin preparation for preventing heavy metal contamination of skin |
-
2014
- 2014-09-15 CN CN201410466323.XA patent/CN104173251B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103783254A (en) * | 2013-07-02 | 2014-05-14 | 吴长海 | Preparation method of yak bone collagen peptide |
| CN103417464A (en) * | 2013-08-09 | 2013-12-04 | 广州市博卡利生物科技有限公司 | Regeneration-type CO2 repair mask and manufacturing method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 牦牛骨胶原蛋白肽与普通牛骨胶原蛋白肽的对比;z小东z;《http://wenku.baidu.com/view/86fdec34bd64783e09122b78.html》;20130806;正文 * |
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