CN107951800A - A kind of Chinese medicine composition that there is anti-ageing anti-wrinkle lifting and compact and preparation method thereof - Google Patents
A kind of Chinese medicine composition that there is anti-ageing anti-wrinkle lifting and compact and preparation method thereof Download PDFInfo
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- CN107951800A CN107951800A CN201711257226.XA CN201711257226A CN107951800A CN 107951800 A CN107951800 A CN 107951800A CN 201711257226 A CN201711257226 A CN 201711257226A CN 107951800 A CN107951800 A CN 107951800A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
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Abstract
The invention discloses a kind of Chinese medicine preparation that there is anti-ageing anti-wrinkle lifting and compact and preparation method thereof, belong to health nursing product technical field.The Chinese medicine preparation is：5 15 parts of ginseng, 10 30 parts of ganoderma lucidum, 15 parts of safflower, 2 10 parts of coix seed, 5 20 parts of motherwort, 3 15 parts of radix astragali, 3 15 parts of sealwort, 5 25 parts of Angelica sinensis, 10 30 parts of peach blossom, 4 15 parts of matrimony vine, 4 15 parts of chrysanthemum, 3 15 parts of Rhizoma Atractylodis Macrocephalae, 3 15 parts of the bletilla striata, 3 15 parts of Radix Paeoniae Alba, 5 15 parts of almond, 4 15 parts of Poria cocos, 13 parts of the fruit of summer cypress, 13 parts of the root bark of shaggy-fruited dittany.Experiment proves that anti-wrinkle effect of the present invention is notable, using the texture that can be obviously improved skin after 30 days, makes skin fine and smooth mellow and full pale, uses energy after 120 days 90 days significantly eye haustra -dsipelling, wrinkles on one's forehead, river word line, crow's feet, decree line and neck line；Raw material acquisition of the present invention is simple, preparation method is convenient, has good application prospect and market prospects.
Description
Technical field
The present invention relates to health nursing product technical field is belonged to, there is the lifting of anti-ageing anti-wrinkle tightly more particularly, to one kind
Cause Chinese medicine preparation of effect and preparation method thereof.
Background technology
Skin is the organ of human body maximum, aging with advancing age.Women 25-30 Sui starts long wrinkle, then
Skin becomes loose, coarse, dull, wrinkle is deepened to become more etc..The aging of skin is almost with everyone lower half a lifetime, to people
Work, life produce negative influence, therefore how wrinkle reduction, slow down aging be health nursing product research focus
One of.
Wrinkle of skin is endogenous factor and the coefficient result of extrinsic factor.By irresistible factor in body
It is naturally-aged those caused by the endogenous factor such as (as gravity, organism endocrine and immune function change) and heredity, shows as
The gradual aging of skin, the natural moisturizing factor in horny layer of epidermis are constantly reduced, and skin water and ability decline, while in skin
Proteoglycan and hyaluronic acid concentration reduce, and the moisture of dermal layer of the skin is reduced, and dermal fibroblast activity is reduced, rubber polymer
The ability of fibrillation declines, and causes to have dry skin, and skin elasticity weakens, and finally produces wrinkle.
By the environmental factor such as causer such as daylight, smoking, occupational harmful chemical to be extrinsic aging, wherein daylight
Middle-ultraviolet lamp irradiation is that the most important factor of skin aging is influenced in environment, they produce active oxygen radical, directly injure skin
The DNA of the skin cell and collagen of extracellular matrix, elastin laminin or mucopolysaccharide molecule, so that thinning of skin, epidermis and corium are handed over
Knit and die down and cell quantity and the reduction of supply vessels quantity, cause facial wrinkles to produce；Further, since the original such as pressure, mood
Because causing skin regulatory function to be damaged, show as having dry skin, loss of elasticity, wrinkle thick depth, leather sample appearance etc..
Anti-wrinkle product currently on the market continues to bring out, and advertisement sentence sentence is tempting, but effect allows people to sigh with feeling.Many skin cares are beautiful
Holding skin care products can only largely be absorbed by skin surface, can not actually enter skin corium and reach profound level more
Purpose new and to collagen supplement, plays the effect of wrinkle anti-aging.Some cosmetics, quickly dispel to reach
" mystery " effect of wrinkle, steroids or other violated components are added rising in skin care item, although anti-wrinkle effect can be rapidly achieved,
But bury hidden trouble for skin health.
Therefore, natural, green, safe and effective Chinese medicine cosmetic increasingly receives the concern of numerous people and likes.In
State just has since ancient times carries out the effect of external application reaches beauty using Chinese medicine Chinese prescription, such as the famous pharmacist Sun Si of the Tang Dynasty is invited at him
Works《Qianjin Yao Fang》Described in included 81 kinds of " face medicine " prescriptions, Ming Dynasty's Li Shizhen《Compendium of Materia Medica》168 kinds are included
It can be used for the Chinese medicine of beauty and skin care.Chinese herbal medicine often has nutrition and curative effect double action concurrently, and acts on and relaxing, and suitably makes up very much
Additive in product.
Chinese medicine cosmetic species is various at present, but the prescription that can really form monarch compatibility is seldom, Chinese medicine restriction or checking relation in five elements
Principle also cause many Chinese medicine materials cannot function as skin care item use.Even if it is according to " the monarch and his subjects help to have part Chinese medicine cosmetic
Make " thinking of making up a prescription, according to pharmacopeia recommended dose scope, the use for determining each taste Chinese medicine in prescription is integrated with reference to doctor personal experience
Amount, but this " dosage determines " based on experiential basis so that Chinese medicine cosmetic lacks the theoretical direction of science and effect is beaten greatly
Discount.
The content of the invention
In view of the above-mentioned problems existing in the prior art, have effects that what anti-ageing anti-wrinkle lifting was compacted this application provides a kind of
Chinese medicine composition and preparation method thereof.Heretofore described each component is arranged in pairs or groups according to special ratios, the multiple efficacies being rich in
Component, which reconciles mutually, to be cooperateed with and plays maximum effect, is removed free radical, is promoted cell turnover and collagen synthesis, significantly improve
The elasticity of skin, compact skin, the effect of fundamentally playing anti-ageing anti-wrinkle.
Technical scheme is as follows：
A kind of Chinese medicine composition for having effects that anti-ageing anti-wrinkle lifting and compacting, is made of the raw material of following parts by weight：
5-15 parts of ginseng, 10-30 parts of ganoderma lucidum, 1-5 parts of safflower, 2-10 parts of coix seed, 5-20 parts of motherwort, radix astragali 3-15
Part, 3-15 parts of sealwort, 5-25 parts of Angelica sinensis, 10-30 parts of peach blossom, 4-15 parts of matrimony vine, 4-15 parts of chrysanthemum, 3-15 parts of Rhizoma Atractylodis Macrocephalae, bletilla striata 3-
15 parts, 3-15 parts of Radix Paeoniae Alba, 5-15 parts of almond, 4-15 parts of Poria cocos, 1-3 parts of the fruit of summer cypress, 1-3 parts of the root bark of shaggy-fruited dittany.
Preferably, the ginseng is used as medicine with whitening purifying substances.
Preferably, the ganoderma lucidum is used as medicine with biting Lactobacillus lactis tunning.
Preferably, the safflower and coix seed are used as medicine after being milled to fine powder.
Present invention also provides the preparation method of above-mentioned Chinese medicine composition, the described method comprises the following steps：
(1) ginseng purification whitening material：5-15 parts of ginsengs are weighed, are milled to powder, deionization is added by solid-liquid ratio 1: 10
Water, water decoct 3 times, each 2h；Merge extracting solution, 4500r/min centrifugation 10min, collect supernatant, concentrate, 80 DEG C of vacuum are done
Dry, obtained dried powder is ginseng skin-whitening crude extract；
(2) glossy ganoderma fermentation product：10-30 portions of ganoderma lucidums are weighed, after being milled to powder, add distilled water sterilizing, acid is bitten in inoculation
Lactobacillus ferment, fermentation condition are：At 37 DEG C, MRS formulas, quiescent culture 24h；It is concentrated under reduced pressure to give medicinal extract for 80 DEG C afterwards；
(3) safflower 1-5 parts and 2-10 parts of coix seed, are milled to fine powder；
(4) motherwort 5-20 parts, 3-15 parts of radix astragali, 3-15 parts of sealwort, 5-25 parts of Angelica sinensis, 10-30 parts of peach blossom, matrimony vine 4-15
Part, 4-15 parts of chrysanthemum, 3-15 parts of Rhizoma Atractylodis Macrocephalae, 3-15 parts of the bletilla striata, 3-15 parts of Radix Paeoniae Alba, 5-15 parts of almond, 4-15 parts of Poria cocos, fruit of summer cypress 1-
3 parts, 1-3 parts of the root bark of shaggy-fruited dittany, it is to boil water three times, be concentrated under reduced pressure to give medicinal extract；
(5) material for respectively obtaining above step mixes jointly, high-temperature sterilization, stands to room temperature to obtain the final product.
The present invention is beneficial to be had technical effect that：
The present invention is substantially exactly that the conglomeration of a large amount of low concentration chemicals is acted on based on Chinese medicine, with toxicology field
Chemicals synergy and low concentration Hormesis mechanism is instruct, with reference to the monarch of China's Traditional Chinese Medicine, minister, the thought helped, made
System, discussion of the Traditional Chinese Medicine for herbal function is combined the achievement in research of traditional Chinese medicine ingredients with modern science, selected suitable
With Chinese herbal medicine, scientific compatibility is carried out with the highest effective concentration of different component Hormesis, then is helped with modern times extraction and microorganism
Fermentation technique, is made the new Chinese medicine preparation for having effects that anti-ageing anti-wrinkle lifting and compacting.
Using the cosmetics as made of the present invention, the elasticity of skin is remarkably improved, skin whitening of compacting, desalinates and dispel wrinkle
Line, the effect of fundamentally playing anti-ageing anti-wrinkle；Pore can be reduced at the same time, improves coarse skin, made skin moisturizing fine and smooth, met
Numerous people pursues young beautiful hope and demand.
Experiment proves that anti-wrinkle effect of the present invention is notable, using the texture that can be obviously improved skin after 30 days, makes skin fine and smooth
It is mellow and full pale, use energy after -120 days 90 days significantly eye haustra -dsipelling, wrinkles on one's forehead, river word line, crow's feet, decree line and neck line；Together
When, raw material acquisition of the present invention is simple, preparation method is convenient, and of low cost, manufacturing process is free from environmental pollution, is easy to by vast consumption
Person receives, and has good application prospect and market prospects.
Embodiment
With reference to embodiment and test case, the present invention is specifically described.
Embodiment 1：
Prepared by the present embodiment have effects that the raw material that anti-ageing anti-wrinkle is lifted used in the Chinese medicine composition to compact is：Ginseng 10
Part, 15 parts of ganoderma lucidum, 2 parts of safflower, 5 parts of coix seed, 10 parts of motherwort, 6 parts of radix astragali, 6 parts of sealwort, 12 parts of Angelica sinensis, 16 parts of peach blossom,
8 parts of matrimony vine, 8 parts of chrysanthemum, 6 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of the bletilla striata, 6 parts of Radix Paeoniae Alba, 10 parts of almond, 8 parts of Poria cocos, 1 part of the fruit of summer cypress, 1 part of the root bark of shaggy-fruited dittany.
The preparation method of Chinese medicine composition described in the present embodiment comprises the following steps：
(1) ginseng purification whitening material：Ginseng is weighed, is milled to powder, deionized water, decocting are added by solid-liquid ratio 1: 10
Boil 3 times, each 2h；Merge extracting solution, 4500r/min centrifugation 10min, collect supernatant, concentrate, 80 DEG C of vacuum drying, obtain
Dried powder be ginseng skin-whitening crude extract；
(2) glossy ganoderma fermentation product：Ganoderma lucidum is weighed, after being milled to powder, adds distilled water sterilizing, Lactobacillus lactis hair is bitten in inoculation
Ferment, fermentation condition are：At 37 DEG C, MRS formulas, quiescent culture 24h；It is concentrated under reduced pressure to give medicinal extract for 80 DEG C afterwards；
(3) safflower and coix seed are milled to fine powder；
(4) take motherwort, radix astragali, sealwort, Angelica sinensis, peach blossom, matrimony vine, chrysanthemum, Rhizoma Atractylodis Macrocephalae, the bletilla striata, Radix Paeoniae Alba, almond, Poria cocos,
Skin, the root bark of shaggy-fruited dittany, it is to boil water three times, be concentrated under reduced pressure to give medicinal extract；
(5) material that four steps obtain more than mixes jointly, and high-temperature sterilization, stands to room temperature to obtain the final product.
Embodiment 2：
Prepared by the present embodiment have effects that the raw material that anti-ageing anti-wrinkle is lifted used in the Chinese medicine composition to compact is：Ginseng 15
Part, 15 parts of ganoderma lucidum, 1 part of safflower, 2 parts of coix seed, 5 parts of motherwort, 3 parts of radix astragali, 3 parts of sealwort, 25 parts of Angelica sinensis, 30 parts of peach blossom,
15 parts of matrimony vine, 15 parts of chrysanthemum, 6 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of the bletilla striata, 6 parts of Radix Paeoniae Alba, 10 parts of almond, 8 parts of Poria cocos, 1 part of the fruit of summer cypress, the root bark of shaggy-fruited dittany 1
Part.The preparation method of the Chinese medicine composition is the same as embodiment 1.
Embodiment 3：
Prepared by the present embodiment have effects that the raw material that anti-ageing anti-wrinkle is lifted used in the Chinese medicine composition to compact is：Ginseng 10
Part, 30 parts of ganoderma lucidum, 2 parts of safflower, 10 parts of coix seed, 20 parts of motherwort, 15 parts of radix astragali, 15 parts of sealwort, 12 parts of Angelica sinensis, peach blossom 16
Part, 8 parts of matrimony vine, 8 parts of chrysanthemum, 15 parts of Rhizoma Atractylodis Macrocephalae, 15 parts of the bletilla striata, 15 parts of Radix Paeoniae Alba, 15 parts of almond, 8 parts of Poria cocos, 1 part of the fruit of summer cypress, shaggy-fruited dittany
1 part of skin.The preparation method of the Chinese medicine composition is the same as embodiment 1.
Embodiment 4：
Prepared by the present embodiment have effects that the raw material that anti-ageing anti-wrinkle is lifted used in the Chinese medicine composition to compact is：5 parts of ginseng,
10 parts of ganoderma lucidum, 5 parts of safflower, 5 parts of coix seed, 10 parts of motherwort, 6 parts of radix astragali, 6 parts of sealwort, 12 parts of Angelica sinensis, 16 parts of peach blossom, Chinese holly
8 parts of Qi, 8 parts of chrysanthemum, 6 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of the bletilla striata, 6 parts of Radix Paeoniae Alba, 10 parts of almond, 15 parts of Poria cocos, 3 parts of the fruit of summer cypress, 3 parts of the root bark of shaggy-fruited dittany.
The preparation method of the Chinese medicine composition is the same as embodiment 1.
Embodiment 5：
Prepared by the present embodiment have effects that the raw material that anti-ageing anti-wrinkle is lifted used in the Chinese medicine composition to compact is：5 parts of ginseng,
5 parts of ganoderma lucidum, 5 parts of safflower, 5 parts of coix seed, 20 parts of motherwort, 15 parts of radix astragali, 15 parts of sealwort, 12 parts of Angelica sinensis, 16 parts of peach blossom, Chinese holly
8 parts of Qi, 8 parts of chrysanthemum, 10 parts of Rhizoma Atractylodis Macrocephalae, 10 parts of the bletilla striata, 10 parts of Radix Paeoniae Alba, 10 parts of almond, 8 parts of Poria cocos, 3 parts of the fruit of summer cypress, the root bark of shaggy-fruited dittany 3
Part.The preparation method of the Chinese medicine composition is the same as embodiment 1.
Test case 1：Toxic side effect is tested
Small white mouse 100 is chosen, weight 20-25g, male and female have both, and are divided into 10 groups, wherein five groups are embodiment 1-
5 normal amount experimental group (0.05g), the another five groups super quantity experimental groups (0.20g) for embodiment 1-5.Using being applied to
The mouse skin position of hair, is smeared once sooner or later daily, continuous to smear 180 days, observes mouse reaction daily.The result shows that：Respectively
Group mouse behavior is without exception, and no poisoning symptom, appetite, excrement are without exception, and general signs are good, shows that the anti-ageing of the present invention is dispelled
The Chinese medicine preparation that wrinkle lifts effect of compacting is safe and free of toxic and side effects.
Test case 2：Remove DPPH free radicals and ABTS Free Radicals
Free radical is the hazardous compound for having caused by body oxidation reaction strong oxidizing property, can damage the group of body
Cell is knitted, it is related to the various acute and chronic diseases such as cancer, aging.This experiment measure embodiment 1-5 remove DPPH free radicals and
The active function of ABTS free radicals.
(1) research of DPPH Free Radicals is removed
1st, instrument and reagent：Ultrasonic extractor, Kunshan Ultrasonic Instruments Co., Ltd.'s production；Multiskan FC filter
The wheeled microplate reader of piece, the production of Thermo companies of the U.S.；EYELA series Rotary Evaporators, the life of TOKYO RIKAKIKAI Co., Ltds
Production；BP-211D type electronic balances, German Sartorius companies production；Electric-heated thermostatic water bath, Tianjin Stettlen instrument are limited
Company produces；Automatically dual pure water distiller, Shanghai Yarong Biochemical Instrument Plant produce SZ-93 types.
Ethanol etc. is that analysis is pure, Beijing Chemical Plant's production；DPPH, the production of Sigma Chemical Co., Ltd.s of the U.S.；Phosphoric acid hydrogen
Disodium, sodium dihydrogen phosphate, Beijing Chemical Plant's production；Deionized water, the self-control of this laboratory.
2nd, prepared by sample solution
The preparation of DPPH sample solutions：Precision weighs 7.88mg DPPH, is dissolved with absolute ethyl alcohol, and constant volume holds in 100mL
It is the DPPH sample solutions of 2.0 × 10-4mol/L in measuring bottle.
3rd, assay method
Embodiment 1-5 is sample to be tested (being configured to 5%, wt%), and positive reference substance is dihydroquercetin sample solution.
Above-mentioned 50 μ L of sample solution are taken to be added in 200 μ L DPPH free radical ethanol solutions respectively, vibration, which shakes up, is placed on 37 DEG C of dark
After standing 30min, 95% ethanol solution does reference, and absorbance B is measured at instrument wavelength 525nm.Measure the DPPH of 200 μ L certainly
It is anhydrous by the absorbance A in base ethanol solution with 50 μ L deionized water mixed liquors, 80 μ L samples aqueous solution of various concentrations and 80 μ L
The absorbance C of alcohol mixeding liquid.Using 96 orifice plates, above-mentioned each sample absorbance is quickly measured.
A：200 μ L DPPH+50 μ L ionized waters (1 hole)；
B：After the dark standing 30min of 200 37 DEG C of μ L DPPH+50 μ L samples solution (3 hole), made with 95% ethanol solution
Reference, measures absorbance at instrument wavelength 525nm；
C：Dark standing is after 30 minutes at+50 37 DEG C of μ L absolute ethyl alcohols (1 hole) of 200 μ L testing sample solutions, with 95%
Ethanol solution makees reference, and absorbance is measured at instrument wavelength 525nm.The activity of radicals scavenging, is calculated by the following formula,
The results are shown in Table 1：
Scavenging activity results of the 1 embodiment 1-5 (5%, wt%) of table to DPPH free radicals
| Embodiment | To the clearance rate (%) of DPPH free radicals |
| Embodiment 1 | 79 |
| Embodiment 2 | 82 |
| Embodiment 3 | 80 |
| Embodiment 4 | 65 |
| Embodiment 5 | 69 |
From table 1 it follows that embodiment 1-3 is stronger (79%-82%) to the Scavenging activity of DPPH free radicals, it is real
The problems such as asking output capacity larger compared with the dosage for being ginseng and ganoderma lucidum by force, consider cost of example 2 and 3 is applied, wherein implementing
The Scavenging activity (79%) of example 1 is also relatively good, is acceptable.Chinese medicine preparation (embodiment 1) i.e. of the invention have compared with
The ability of good removing DPPH.
(2) Effect study of ABTS free radicals is removed
1st, instrument and reagent：
The wheeled microplate reader of Multiskan FC optical filters, the production of Thermo companies of the U.S.；BP-211D type electronic balances, moral
Sartorius companies of state produce；Electric-heated thermostatic water bath, the production of Tianjin Stettlen Instrument Ltd.；SZ-93 types are automatically dual
Pure water distiller, Shanghai Yarong Biochemical Instrument Plant's production；Pipettor (1-100 μ l, 100-1000 μ l), Capp Aps companies of Denmark
Production.
K2SO8Etc. be analysis it is pure, Beijing Chemical Plant production；ABTS, Sigma company produce.
2nd, the preparation of sample solution
The ABTS solution of 7mmol/L and the K of 2.45mmol/l are configured to deionized water2SO8Solution, takes K2SO8Solution
5mL, is added in 15mL ABTS solution, is placed in reaction 16h at dark at room temperature, forms ABTS free radical storing solutions.
3rd, test method
With 50 μ L of liquid-transfering gun absorption testing sample solution, (embodiment 1-5 is sample to be tested, is configured on 96 orifice plates
5%, wt%), add and pass through diluted 200 μ L of ABTS free-atom aqueous solutions, in triplicate, vibration is mixed for each testing sample solution
It is even, 30min is reacted at room temperature, its absorbance is measured at 734nm with microplate reader.Blank control applies some make up sample solution
Matrix replaces.The absorbance of sample solution is A1, and the absorbance of blank control is A2.The activity of radicals scavenging, by following
Formula calculates, and the results are shown in Table 2：
Scavenging activity results of the 2 embodiment 1-5 (5%, wt%) of table to ABTS free radicals
| Embodiment | To the clearance rate (%) of ABTS free radicals |
| Embodiment 1 | 92 |
| Embodiment 2 | 90 |
| Embodiment 3 | 91 |
| Embodiment 4 | 85 |
| Embodiment 5 | 80 |
All stronger to the Scavenging activity of ABTS free radicals as can be seen from Table 2, wherein the Scavenging activity of embodiment 1 is most
By force (for 92%), it was demonstrated that Chinese medicine preparation (embodiment 1) of the invention has good effect to ABTS free radicals, can effectively dispel
Wrinkle crease-resistant.
Test case 3：Anti-wrinkle effect is tested
Inventor by the present invention anti-ageing anti-wrinkle lifting compact effect Chinese medicine preparation be used for face it is dim it is yellow, dry, coarse,
There are 300 volunteers of the skin problems such as wrinkle, test position is the face of volunteer.Smear 0.5g Chinese medical extracts extremely every time
Fully absorb, smear once sooner or later daily, can generally be obviously improved the texture of skin after 30 days, make skin fine and smooth mellow and full white
It is fair-skinned, use energy after -120 days 90 days significantly eye haustra -dsipelling, wrinkles on one's forehead, river word line, crow's feet, decree line and neck line.As a result such as table 3
It is shown.
3 volunteer of table lifts the result for effect Chinese medicine preparation that compacts using anti-ageing anti-wrinkle
To sum up, the compact Chinese medicine preparation of effect of anti-ageing anti-wrinkle lifting of the invention is tested by long-term volunteer, can be bright
The aobvious elasticity for improving skin, compact skin, the effect of fundamentally playing anti-ageing anti-wrinkle, and effective percentage was up to 95.0%, 180 day within 30 days
All effective (embodiment 1).
The above, is only the preferable case study on implementation of the present invention, and limitation in any form is not done to the present invention,
Therefore all contents without departing from technical solution of the present invention, any letter that the technical spirit according to the present invention does above case study on implementation
Single modification, equivalent variations and modification, in the range of still falling within technical solution of the present invention.
Claims (5)
1. a kind of Chinese medicine composition that there is anti-ageing anti-wrinkle lifting and compact, it is characterised in that by the raw material of following parts by weight
Composition：
5-15 parts of ginseng, 10-30 parts of ganoderma lucidum, 1-5 parts of safflower, 2-10 parts of coix seed, 5-20 parts of motherwort, 3-15 parts of radix astragali,
3-15 parts of sealwort, 5-25 parts of Angelica sinensis, 10-30 parts of peach blossom, 4-15 parts of matrimony vine, 4-15 parts of chrysanthemum, 3-15 parts of Rhizoma Atractylodis Macrocephalae, bletilla striata 3-15
Part, 3-15 parts of Radix Paeoniae Alba, 5-15 parts of almond, 4-15 parts of Poria cocos, 1-3 parts of the fruit of summer cypress, 1-3 parts of the root bark of shaggy-fruited dittany.
2. Chinese medicine composition according to claim 1, it is characterised in that the ginseng is used as medicine with whitening purifying substances.
3. Chinese medicine composition according to claim 1, it is characterised in that the ganoderma lucidum is entered with biting Lactobacillus lactis tunning
Medicine.
4. Chinese medicine composition according to claim 1, it is characterised in that after the safflower and coix seed are milled to fine powder
It is used as medicine.
A kind of 5. preparation method of Claims 1 to 4 any one of them Chinese medicine composition, it is characterised in that：The method bag
Include following steps：
(1) ginseng purification whitening material：5-15 parts of ginsengs are weighed, are milled to powder, deionized water, water are added by solid-liquid ratio 1: 10
Decoct 3 times, each 2h；Merge extracting solution, 4500r/min centrifugation 10min, collect supernatant, concentrate, 80 DEG C of vacuum drying, obtain
To dried powder be ginseng skin-whitening crude extract；
(2) glossy ganoderma fermentation product：10-30 portions of ganoderma lucidums are weighed, after being milled to powder, add distilled water sterilizing, yogurt bar is bitten in inoculation
Bacterium is fermented, and fermentation condition is：At 37 DEG C, MRS formulas, quiescent culture 24h；It is concentrated under reduced pressure to give medicinal extract for 80 DEG C afterwards；
(3) safflower 1-5 parts and 2-10 parts of coix seed, are milled to fine powder；
(4) motherwort 5-20 parts, 3-15 parts of radix astragali, 3-15 parts of sealwort, 5-25 parts of Angelica sinensis, 10-30 parts of peach blossom, 4-15 parts of matrimony vine,
4-15 parts of chrysanthemum, 3-15 parts of Rhizoma Atractylodis Macrocephalae, 3-15 parts of the bletilla striata, 3-15 parts of Radix Paeoniae Alba, 5-15 parts of almond, 4-15 parts of Poria cocos, fruit of summer cypress 1-3
Part, 1-3 parts of the root bark of shaggy-fruited dittany, it is to boil water three times, be concentrated under reduced pressure to give medicinal extract；
(5) material for respectively obtaining above step mixes jointly, high-temperature sterilization, stands to room temperature to obtain the final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711257226.XA CN107951800A (en) | 2017-12-03 | 2017-12-03 | A kind of Chinese medicine composition that there is anti-ageing anti-wrinkle lifting and compact and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201711257226.XA CN107951800A (en) | 2017-12-03 | 2017-12-03 | A kind of Chinese medicine composition that there is anti-ageing anti-wrinkle lifting and compact and preparation method thereof |
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| CN110193001A (en) * | 2019-06-27 | 2019-09-03 | 毛春红 | It is a kind of it is flat wrinkle, compact, tender skin Chinese medicinal skin care stoste and its production method |
| CN114288233A (en) * | 2021-12-02 | 2022-04-08 | 科丝美诗(中国)化妆品有限公司 | Composition for promoting metabolism of aged skin and preparation method and application thereof |
| CN116077409A (en) * | 2022-12-31 | 2023-05-09 | 杭州纽龙日尚生物制品有限公司 | Collagen activator and preparation method and application thereof |
| CN117731731A (en) * | 2023-12-13 | 2024-03-22 | 广州市白云莱茵化妆品厂 | Preparation method and application of anti-aging traditional Chinese medicine extract |
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| CN103906526A (en) * | 2011-10-25 | 2014-07-02 | 株式会社爱茉莉太平洋 | Wrap fermentation method using medicinal flower, and composition for external application onto the skin using same |
| CN104208503A (en) * | 2014-08-26 | 2014-12-17 | 苗广伟 | Medicine for beautifying and removing wrinkles and preparation method thereof |
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| KR20120063646A (en) * | 2010-12-08 | 2012-06-18 | 김보라 | A processing method of liquid by using salmon testis extract for anti-aging and anti-oxidant care |
| CN103906526A (en) * | 2011-10-25 | 2014-07-02 | 株式会社爱茉莉太平洋 | Wrap fermentation method using medicinal flower, and composition for external application onto the skin using same |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110193001A (en) * | 2019-06-27 | 2019-09-03 | 毛春红 | It is a kind of it is flat wrinkle, compact, tender skin Chinese medicinal skin care stoste and its production method |
| CN114288233A (en) * | 2021-12-02 | 2022-04-08 | 科丝美诗(中国)化妆品有限公司 | Composition for promoting metabolism of aged skin and preparation method and application thereof |
| CN114288233B (en) * | 2021-12-02 | 2023-09-01 | 科丝美诗(中国)化妆品有限公司 | Composition for promoting metabolism of aged skin and preparation method and application thereof |
| CN116077409A (en) * | 2022-12-31 | 2023-05-09 | 杭州纽龙日尚生物制品有限公司 | Collagen activator and preparation method and application thereof |
| CN117731731A (en) * | 2023-12-13 | 2024-03-22 | 广州市白云莱茵化妆品厂 | Preparation method and application of anti-aging traditional Chinese medicine extract |
| CN117731731B (en) * | 2023-12-13 | 2024-05-24 | 广州市白云莱茵化妆品厂 | Preparation method and application of anti-aging traditional Chinese medicine extract |
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Application publication date: 20180424 |