CN114099391A - Cosmetic composition with whitening, moisturizing and antioxidant effects and preparation method thereof - Google Patents
Cosmetic composition with whitening, moisturizing and antioxidant effects and preparation method thereof Download PDFInfo
- Publication number
- CN114099391A CN114099391A CN202111617644.1A CN202111617644A CN114099391A CN 114099391 A CN114099391 A CN 114099391A CN 202111617644 A CN202111617644 A CN 202111617644A CN 114099391 A CN114099391 A CN 114099391A
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- Prior art keywords
- composition
- moisturizing
- cosmetic composition
- whitening
- antioxidant effects
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- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention discloses a cosmetic composition with whitening, moisturizing and antioxidant effects and a preparation method thereof, wherein cell walls of raw materials of radix rehmanniae, burdock and black bean are damaged by biological enzyme, so that active substances in raw material cells are easier to extract by a solvent, and then the biological enzyme is inactivated by using ethanol with higher concentration, thereby avoiding the problems of degradation of the active substances in the raw materials and energy waste caused by enzyme inactivation due to high-temperature heating in the extraction process of the traditional enzyme method, and better preserving the active substances in the raw materials; the cosmetic composition can be widely applied to cream emulsion and water as a cosmetic raw material, has a wide application range and is convenient to use, and the traditional ancient formula adopts a medicinal liquor oral form, so that the use limitation is great; the invention has practical efficacy experiment as an adjuvant and stronger persuasion compared with the ancient formula. The ancient recipe for beauty treatment in China has been in existence for thousands of years, so that the ancient recipe for beauty treatment has certain efficacy and rationality.
Description
Technical Field
The invention relates to the field of cosmetics, and particularly relates to a cosmetic composition with whitening, moisturizing and antioxidant effects and a preparation method thereof.
Background
The kidney tonifying rehmannia wine is a beautifying prescription recorded in the upper part of the book of endowment, and the prescription records: 500 g of dried rehmannia root, cut. 4000 g of soybean, decocted. Raw burdock root, radix Arctii 2000 g, cut. The medicine is contained in a silk bag and is soaked in 6600 ml of wine for five or six days. The blackish facial patch is mainly used for blackish facial patch, moistening skin and hair, tonifying qi and deficiency and lack. Blackish patch is a dry black flour. The formula has effects of whitening, moisturizing and softening skin.
In the formula, black beans are used as main drugs, and the black beans are black seeds of soybeans and are plants in the genus of Glycine of the subfamily Papilionaceae of Leguminosae. The medicated semen Sojae Atricolor from compendium of materia Medica has effects of invigorating kidney, nourishing blood, clearing heat, detoxicating, promoting blood circulation, removing blood stasis, blackening hair, improving eyesight, and prolonging life. "secret record of longevity": taking semen Sojae Atricolor can make people skin and skin grow, benefit color, fill essence and marrow, and add strength. The book of 'Yangshan' records: li Du Yu swallows seven black beans every morning, which is called five zang-organs valley and is not aged. "
The black bean contains rich vitamins, yolk, melanin and other substances, wherein the contents of B vitamins and vitamin E are high, the black bean has the functions of nutrition and health care, and the black bean also contains rich trace elements, so that the function integrity of the organism can be kept, the aging of the organism can be delayed and the like. The black bean polysaccharide has an immunosuppressive effect on the phagocytic function of phagocytes, so that the phagocytic function of the phagocytes is reduced, and the corresponding active oxygen is reduced; it also has immunosuppressive effect on leukocyte by indirectly scavenging active oxygen. In addition, the black soybean pigment has the function of directly eliminating active oxygen generated by a cell system and a non-cell system.
In the formula, burdock is used as an adjuvant, and the burdock is a burdock plant of Compositae. The burdock contains various vitamins and minerals required by human bodies, such as inulin, cellulose, protein, calcium, phosphorus, iron and the like, wherein the content of carotene is 150 times higher than that of carrot, and the content of protein and calcium is the first of rhizomes. The radix Arctii contains inulin and volatile oil, arctic acid, multiple polyphenols and aldehydes, and is rich in cellulose and amino acids. The burdock has the functions of resisting bacteria, reducing blood sugar, resisting aging and eliminating oxygen free radicals.
The raw rehmannia root in the recipe has a cold nature, and is recorded in the book of cosmetic plant raw materials: rehmannia is a plant of the Scrophulariaceae family, and comprises two kinds of radix rehmanniae and prepared rhizome of rehmannia, and the cosmetic adopts root extract, mainly radix rehmanniae. The rehmanniae radix contains iridoid glycoside as main ingredient, and catalpol etc.; the alkaloid is adenosine; the saccharide compound includes mannitol. The rehmanniae radix extract has effects of promoting cholesterol generation, changing sebum composition, and softening and moistening skin by combining its antioxidant and moisture absorption capacity under low humidity environment.
Although the data show that the kidney tonifying rehmannia wine has certain rationality, the formula is orally taken, so that the use is inconvenient, and the effect of the formula is not verified by a clear effect experiment, so that the formula has great history limitation.
The prior art discloses a beauty and skin care enzyme liquid and application thereof (publication number CN 105012225A), wherein the beauty and skin care enzyme liquid comprises the following raw materials: malt, yeast and functional raw materials. The functional raw materials are selected from four to ten of the following components: ginseng, walnut kernel, almond, tuckahoe, coix seed, wolfberry fruit, liquorice root, scutellaria root, kudzu root, rhodiola root, bletilla striata root, burdock root, rose, dandelion, tea, lophatherum gracile, centella asiatica leaf, chrysanthemum, gardenia, purslane, evening primrose, hop and motherwort. The ferment facial mask essence containing the beauty and skin care ferment liquid can help activate skin cells and promote metabolism. But cannot better preserve the active substances in the raw materials and has great application limitations.
Disclosure of Invention
The invention aims to provide a cosmetic composition with whitening, moisturizing and antioxidant effects and a preparation method thereof.
The technical scheme adopted by the invention is as follows:
a cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following components: the composition comprises a raw rehmannia root extract, a burdock extract, a black bean extract and deionized water, wherein the raw rehmannia root extract accounts for 0.05-0.2% of the total weight of the composition, the burdock extract accounts for 0.1-0.2% of the total weight of the composition, the black bean extract accounts for 0.1-0.5% of the total weight of the composition, an organic solvent accounts for 20-30% of the total weight of the composition, and the deionized water accounts for 69.1-79.75% of the total weight of the composition.
Further, the organic solvent is butanediol or dipropylene glycol.
Further, a preparation method of the cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following steps:
step 1: adding 5-10 times of deionized water into 1-2 parts of radix rehmanniae recen, 2-4 parts of burdock and 6-8 parts of black bean according to a proportion, adding 1-3% of cellulase and 1-3% of pectinase, carrying out enzymolysis for 1-2 hours at 30-40 ℃, then adding 5-10 times of 95% ethanol, carrying out water bath for 5-7 hours at 50-70 ℃, filtering with a 1-3 mu m filter paper plate to obtain a filtrate, and detecting the solid content of the filtrate; the burdock and the black bean contain abundant pectin, so that cellulase and pectinase are required to be used together;
step 2: concentrating the filtrate obtained in the step 1 until the filtrate is 1/3-1/5 of the original weight, adding an organic solvent to make the total amount of the organic solvent reach 30-50% of the stock solution, and preparing the stock solution;
and step 3: using 20-30% of organic solvent aqueous solution to prepare the stock solution according to the ratio of 1: diluting at ratio of 5-1:10, and filtering with 0.22-0.45 μm filter membrane to obtain the cosmetic composition.
Further, an application of the cosmetic composition with whitening, moisturizing and antioxidant effects in cosmetics.
Further, the composition can be prepared into any selected dosage form of cream, lotion and smoothing toner.
The invention has the beneficial effects that: 1. the cell walls of the raw materials of the radix rehmanniae recen, the burdock and the black bean are damaged by using the biological enzyme, so that active substances in raw material cells are easier to extract by a solvent, and then the biological enzyme is inactivated by using the ethanol with higher concentration, thereby avoiding the problems of degradation of the active substances in the raw materials and energy waste caused by enzyme inactivation due to high-temperature heating in the traditional enzymatic extraction process, and better preserving the active substances in the raw materials;
2. the cosmetic composition can be widely applied to cream emulsion and water as a cosmetic raw material, has a wide application range and is convenient to use, and the traditional ancient formula adopts a medicinal liquor oral form, so that the use limitation is great;
3. the invention has practical efficacy experiment as an adjuvant and stronger persuasion compared with the ancient formula. The ancient recipe for beauty treatment in China has been in existence for thousands of years, so that the ancient recipe for beauty treatment has certain efficacy and rationality.
Drawings
The present invention will be described in further detail with reference to the accompanying drawings and specific embodiments.
FIG. 1 is a graph showing the results of the inhibition of tyrosinase activity by SNH complexes in the assay for the inhibition of tyrosinase activity by SNH complexes of the present invention;
FIG. 2 is a graph of the SNH complex scavenging DPPH test results in the SNH complex scavenging DPPH free radical test assay of the present invention;
FIG. 3 is the average difference of the variation of the moisture content of the skin of 0.5h in the SNH compound moisturizing efficacy test of the present invention;
FIG. 4 is the average difference of the skin moisture content changes at 1.0h in the SNH complex moisturizing efficacy test of the present invention;
FIG. 5 is the average difference in skin moisture content change over 1.5h in a SNH composite moisturizing efficacy test of the present invention;
FIG. 6 is the average difference of the skin moisture content changes of 2.0h in the SNH compound moisturizing efficacy test of the present invention;
FIG. 7 is the average difference of the skin moisture content changes at 4.0h in the SNH complex moisturizing efficacy test of the present invention;
fig. 8 is the average difference of the moisture content change of the skin at 6.0h in the SNH complex moisturizing efficacy test of the present invention.
Detailed Description
Example 1
A cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following components: the composition comprises a raw rehmannia root extract, a burdock extract, a black bean extract and deionized water, wherein the raw rehmannia root extract accounts for 0.05 percent of the total weight of the composition, the burdock extract accounts for 0.1 percent of the total weight of the composition, the black bean extract accounts for 0.1 percent of the total weight of the composition, an organic solvent accounts for 20 percent of the total weight of the composition, and the deionized water accounts for 69.1 percent of the total weight of the composition. The organic solvent is butanediol. The invention combines the modern plant extraction process with the traditional Chinese beauty ancient prescription, uses biological enzyme to destroy the cell walls of the raw materials of the radix rehmanniae recen, the burdock and the black bean, so that the active substances in the raw material cells are easier to be extracted by a solvent, then uses ethanol with higher concentration to inactivate the biological enzyme, avoids the problems of degradation of the active substances in the raw materials and energy waste caused by enzyme inactivation by high-temperature heating in the extraction process of the traditional enzyme method, and better preserves the active substances in the raw materials.
A preparation method of a cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following steps:
step 1: adding 1 part of radix rehmanniae, 2 parts of burdock and 6 parts of black bean into 5 times of deionized water according to a ratio, adding 1% of cellulase and 1% of pectinase, carrying out enzymolysis for 1 hour at the temperature of 30 ℃, then adding 5 times of 95% ethanol, carrying out water bath for 5 hours at the temperature of 50 ℃, filtering by using a 1-micrometer filter paper plate to obtain a filtrate, and detecting the solid content of the filtrate;
step 2: concentrating the filtrate obtained in the step 1 until the weight of the filtrate is 1/3 of the original weight, adding butanediol to enable the total weight of butanediol to reach 30% of the stock solution, and preparing the stock solution;
and step 3: the stock solution was diluted with a 20% aqueous solution of butylene glycol at a ratio of 1: 5 diluting, and filtering with 0.22 μm filter membrane to obtain the cosmetic composition.
A cosmetic composition with whitening, moisturizing and antioxidant effects is applied in cosmetics, and is made into one of cream, lotion and smoothing toner.
The cosmetic composition can be widely applied to cream emulsion and water as a cosmetic raw material, and has wide application range and convenient use; the traditional ancient formula adopts a medicinal liquor oral administration form, so that the use limitation is great; the invention has practical efficacy experiment as an adjuvant and stronger persuasion compared with the ancient formula. The ancient recipe for beauty treatment in China has been in existence for thousands of years, so that the ancient recipe for beauty treatment has certain efficacy and rationality.
Example 2
A cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following components: the composition comprises a raw rehmannia root extract, a burdock extract, a black bean extract and deionized water, wherein the raw rehmannia root extract accounts for 0.2 percent of the total weight of the composition, the burdock extract accounts for 0.2 percent of the total weight of the composition, the black bean extract accounts for 0.5 percent of the total weight of the composition, an organic solvent accounts for 30 percent of the total weight of the composition, and the deionized water accounts for 79.75 percent of the total weight of the composition. The organic solvent is dipropylene glycol. The invention combines the modern plant extraction process with the traditional Chinese beauty ancient prescription, uses biological enzyme to destroy the cell walls of the raw materials of the radix rehmanniae recen, the burdock and the black bean, so that the active substances in the raw material cells are easier to be extracted by a solvent, then uses ethanol with higher concentration to inactivate the biological enzyme, avoids the problems of degradation of the active substances in the raw materials and energy waste caused by enzyme inactivation by high-temperature heating in the extraction process of the traditional enzyme method, and better preserves the active substances in the raw materials.
A preparation method of a cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following steps:
step 1: adding 2 parts of radix rehmanniae, 4 parts of burdock and 8 parts of black bean into 10 times of deionized water according to a ratio, adding 1-3% of cellulase and 3% of pectinase, carrying out enzymolysis for 2 hours at 40 ℃, then adding 10 times of 95% ethanol, carrying out water bath for 7 hours at 70 ℃, filtering by using a 3-micrometer filter paper plate to obtain a filtrate, and detecting the solid content of the filtrate;
step 2: concentrating the filtrate obtained in the step 1 until the filtrate reaches 1/5 of the original weight, adding dipropylene glycol to enable the total amount of the dipropylene glycol to reach 50% of the original liquid, and preparing the original liquid;
and step 3: the stock solution was diluted with 30% dipropylene glycol aqueous solution at a ratio of 1:10, and filtered through a 0.45 μm filter to obtain the cosmetic composition.
Application of a cosmetic composition with whitening, moisturizing and antioxidant effects in cosmetics. The composition can be made into any selected dosage form of cream, lotion, and smoothing toner.
The cosmetic composition can be widely applied to cream emulsion and water as a cosmetic raw material, and has wide application range and convenient use; the traditional ancient formula adopts a medicinal liquor oral administration form, so that the use limitation is great; the invention has practical efficacy experiment as an adjuvant and stronger persuasion compared with the ancient formula. The ancient recipe for beauty treatment in China has been in existence for thousands of years, so that the ancient recipe for beauty treatment has certain efficacy and rationality.
Example 3
A cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following components: the composition comprises a raw rehmannia root extract, a burdock extract, a black bean extract and deionized water, wherein the raw rehmannia root extract accounts for 0.12% of the total weight of the composition, the burdock extract accounts for 0.15% of the total weight of the composition, the black bean extract accounts for 0.3% of the total weight of the composition, an organic solvent accounts for 25% of the total weight of the composition, and the deionized water accounts for 75.5% of the total weight of the composition. The organic solvent is butanediol. The invention combines the modern plant extraction process with the traditional Chinese beauty ancient prescription, uses biological enzyme to destroy the cell walls of the raw materials of the radix rehmanniae recen, the burdock and the black bean, so that the active substances in the raw material cells are easier to be extracted by a solvent, then uses ethanol with higher concentration to inactivate the biological enzyme, avoids the problems of degradation of the active substances in the raw materials and energy waste caused by enzyme inactivation by high-temperature heating in the extraction process of the traditional enzyme method, and better preserves the active substances in the raw materials.
A preparation method of a cosmetic composition with whitening, moisturizing and antioxidant effects comprises the following steps:
step 1: adding 7.5 times of deionized water into 1.5 parts of radix rehmanniae, 3 parts of burdock and 7 parts of black bean according to a ratio, adding 2% of cellulase and 2% of pectinase, carrying out enzymolysis for 1.5 hours at 35 ℃, then adding 7.5 times of 95% ethanol, carrying out water bath for 6 hours at 60 ℃, filtering by using a 2 mu m filter paper plate to obtain a filtrate, and detecting the solid content of the filtrate;
step 2: concentrating the filtrate obtained in the step 1 until the weight of the filtrate is 1/4 of the original weight, adding butanediol to enable the butanediol to reach 40% of the total weight of the stock solution, and preparing the stock solution;
and step 3: the stock solution was diluted with 25% aqueous butanediol at a ratio of 1: 7 diluting, and filtering with 0.34 μm filter membrane to obtain the cosmetic composition.
A cosmetic composition with whitening, moisturizing and antioxidant effects is applied in cosmetics, and is made into one of cream, lotion and smoothing toner.
The cosmetic composition can be widely applied to cream emulsion and water as a cosmetic raw material, and has wide application range and convenient use; the traditional ancient formula adopts a medicinal liquor oral administration form, so that the use limitation is great; the invention has practical efficacy experiment as an adjuvant and stronger persuasion compared with the ancient formula. The ancient recipe for beauty treatment in China has been in existence for thousands of years, so that the ancient recipe for beauty treatment has certain efficacy and rationality.
Example 4
Assay for inhibition of tyrosinase Activity by SNH Complex
1. The purpose is as follows: the half inhibitory concentration of the SNH complex on tyrosinase activity was determined.
2. Materials: SNH Complex (i.e. the present cosmetic example 1 composition)
Sample preparation: buffer solution: k2HPO4（8.71g/500mL）+KH2PO4（6.805g/500mL）→pH=6.80 （±0.02）
Substrate: about 0.3mg/mL of L-tyrosine
A spectrophotometer: uv, 480nm
3. The method comprises the following steps:
(1) enzyme concentration selection:
taking a small amount of enzyme, dissolving the enzyme by using a buffer solution, wherein the color is brown; adding 500. mu.L of (L-tyrosine (0.3 mg/mL)), 500. mu.L of buffer solution, 450. mu.L of pure water and 50. mu.L of enzyme into a 1.5mL centrifuge tube; before adding enzyme, at 37 deg.C for 20 min; after the addition of the enzyme, the absorbance was measured at a wavelength of 480nm in a spectrophotometer at 37 ℃ for 10min (enzyme addition-test). The enzyme concentration was adjusted to give an Absorbance (ABS) of between 0.45 and 0.55. The enzyme solution at this concentration was used as an experimental enzyme solution.
(2) Experimental addition
(3) Measuring absorbance at 480nm, making table, and plotting to obtain IC50。
Calculating the formula: inhibition (%) = [1- (S-SB)/(C-CB) ] +100
Note that: before adding enzyme, water bath is carried out at 37 ℃ for 20 min; after adding enzyme, water bath at 37 deg.C, (adding enzyme-testing time) for 10min, and measuring absorbance at 480nm wavelength of spectrophotometer. Water bath at 37 deg.C for 20min without enzyme.
4. Results
Results of inhibition of tyrosinase activity by SNH complexes table:
S：Sample SB：Sample Blank C：Control CB：Control Blank
as a result, as shown in FIG. 1: the SNH complex has extremely strong effect of inhibiting tyrosinase activity, and the IC50 value is about 16 mu L/mL.
And (4) conclusion: the SNH compound has strong tyrosinase activity inhibiting effect and strong whitening effect.
Example 5
SNH complex scavenging DPPH free radical assay
1. Reagent preparation
(1) 3.943mgDPPH was made up to 50mL with 95% ethanol
(2) About 10mg of Trolox is fixed to 100mL by 95% ethanol
(3) SNH Complex (i.e. the present cosmetic example 2 composition)
2. Experimental procedure
(1) UV zero calibration, 95% ethanol as blank
(2) Preliminary experiments (DPPH concentration selection)
Shaking 500 μ L DPPH +1000 μ L95% ethanol for 10s, standing for 10min, and measuring absorbance (absorbance at 520nm of 0.45-0.55, can be used as DPPH solution for the following experiment)
(3) Determination of Trolox
Adding DPPH or 95% ethanol, shaking for 10s, standing for 10min, and measuring absorbance
(4) Experiment of
Adding DPPH or 95% ethanol, shaking for 10s, and standing for 10min
(5) The absorbance at 520nm was measured, tabulated and plotted to obtain the IC50 value.
Calculating the formula: inhibition (%) = [1- (S-SB)/(C-CB) ] +100
3. Results
As a result, as shown in FIG. 2: the SNH complex has the function of eliminating DPPH free radicals, and the IC50 value is about 133 uL/mL.
And (4) conclusion: the SNH compound has the function of eliminating DPPH free radicals and has strong antioxidant effect.
Example 6
SNH complex moisturizing efficacy test
1. Experimental Material
The instrument comprises the following steps: corneometer CMB25 (Germany CK company)
And (3) testing a sample: SNH Complex (i.e. the present cosmetic example 3 composition)
2. Conditions of the experiment
(I) indoor Environment
② no strong sunlight or direct lighting
③ the ambient temperature is 20 +/-2 ℃ and the ambient humidity is 40-60 percent
3. Subject conditions: 30 subjects aged 18-60 years
4. Working principle of skin moisture content
The moisture content of the skin can be measured by adopting a worldwide accepted Cornemeter-capacitance method, the principle of which is based on that the dielectric constant (< 7) of water (81) and other substances is changed greatly, and a properly-shaped measuring capacitor changes along with the change of the capacitance of the skin according to the difference of water content, and the capacitance of the skin is in a measuring range. The capacitance measuring method is superior to other methods in that the test result is practically not affected by polarization effect and ionic conductivity since the skin to be tested is not in unnatural contact with the test probe and almost no current flows through the skin to be tested. The instrument probe and the water in the skin have no inertia in the process of establishing balance, and can realize quick measurement, thereby eliminating the influence of active skin on the measurement result.
5. Test procedure
Testing an area: inner side of forearm
② preparation before testing
The whitening effect products (cosmetics, external medicines or internal health products) cannot be used 2-3 days before the tested part, the testee needs to uniformly clean the inner side of the forearm before the test, the forearm is wiped clean by dry facial tissue, the measuring area mark is made on the inner side of the forearm of the testee after the cleaning, the testee needs to sit still for at least 30min in a room meeting the standard before formal test, the forearm is exposed and placed in a testing state to keep relaxed.
③ the inner side of the forearm in the experiment is marked with 2 multiplied by 4cm2 experiment area, the same arm can mark a plurality of areas at the same time, and the areas are spaced by 2 cm. The test products and the blank control are randomly distributed on the forearm, the blank value of 30min after cleaning of each test area is firstly measured, then the test sample is uniformly coated in the experimental area by using a latex finger cot according to the dosage of 2.0 +/-0.1 mg sample/cm 2, and the skin moisture content of the test area and the control area is respectively measured after the test sample and the control area are coated for 0.5h, 1.0h, 1.5h, 2.0h, 4.0h, 6.0 h. The measurements of the same volunteer were performed by the same measurement staff.
6. Measurement index
Skin moisture content determination: the measurement was performed 3 times, and the average value was taken.
7. Control format
Different treatment controls were performed using the same.
8. Statistical method
Performing paired t-test
9. Results and analysis
(1) Participating in the measurement results of the testers, as shown in FIGS. 3-8;
(2) analysis of
After the SNH compound is used for 6 hours, the skin moisturizing effect of a population is evaluated, and the volunteers have no adverse reactions such as allergy during the use period.
After trial for 6h, the experimental data were analyzed as follows, two-tailed test, t0.05 (4) =2.776
As a result: through statistical analysis, after the samples are used for 0.5h, 1.0h, 1.5h, 2.0h, 4.0h and 6.0h, the SNH compound has the moisturizing effect, and the moisturizing time is 2.0 h. The difference has statistical significance, and the SNH compound has a moisturizing effect, and the moisturizing time is 2.0 h.
And (4) conclusion: the SNH compound has good moisturizing effect within 2 hours.
The above-mentioned embodiments are merely illustrative of the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various modifications and improvements made to the technical solution of the present invention by those skilled in the art without departing from the spirit of the present invention should be included in the protection scope defined by the claims of the present invention.
Claims (5)
1. A cosmetic composition with whitening, moisturizing and antioxidant effects is characterized in that: the composition consists of the following components: the composition comprises a raw rehmannia root extract, a burdock extract, a black bean extract and deionized water, wherein the raw rehmannia root extract accounts for 0.05-0.2% of the total weight of the composition, the burdock extract accounts for 0.1-0.2% of the total weight of the composition, the black bean extract accounts for 0.1-0.5% of the total weight of the composition, an organic solvent accounts for 20-30% of the total weight of the composition, and the deionized water accounts for 69.1-79.75% of the total weight of the composition.
2. A cosmetic composition with whitening, moisturizing and antioxidant effects is characterized in that: the organic solvent is butanediol or dipropylene glycol.
3. The preparation method of the cosmetic composition with whitening, moisturizing and antioxidant effects according to claim 1, wherein the preparation method comprises the following steps: the method comprises the following steps:
step 1: adding 5-10 times of deionized water into 1-2 parts of radix rehmanniae recen, 2-4 parts of burdock and 6-8 parts of black bean according to a proportion, adding 1-3% of cellulase and 1-3% of pectinase, carrying out enzymolysis for 1-2 hours at 30-40 ℃, then adding 5-10 times of 95% ethanol, carrying out water bath for 5-7 hours at 50-70 ℃, filtering with a 1-3 mu m filter paper plate to obtain a filtrate, and detecting the solid content of the filtrate;
step 2: concentrating the filtrate obtained in the step 1 until the filtrate is 1/3-1/5 of the original weight, adding an organic solvent to make the total amount of the organic solvent reach 30-50% of the stock solution, and preparing the stock solution;
and step 3: using 20-30% of organic solvent aqueous solution to prepare the stock solution according to the ratio of 1: diluting at ratio of 5-1:10, and filtering with 0.22-0.45 μm filter membrane to obtain the cosmetic composition.
4. Application of a cosmetic composition with whitening, moisturizing and antioxidant effects in cosmetics.
5. The application of the cosmetic composition with the whitening, moisturizing and antioxidant effects in cosmetics according to claim 4 is characterized in that: the composition can be made into any selected dosage form of cream, lotion, and smoothing toner.
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| CN115737495A (en) * | 2022-10-26 | 2023-03-07 | 现代百朗德生物科技(江苏)有限公司 | Siji flower essence extracting solution with anti-inflammatory, antioxidant, whitening and anti-wrinkle effects and preparation method thereof |
| CN115869225A (en) * | 2022-10-26 | 2023-03-31 | 现代百朗德生物科技(江苏)有限公司 | Peach-red four-ingredient soup cosmetic composition with whitening, antioxidant and anti-wrinkle effects and application of peach-red four-ingredient soup cosmetic composition in cosmetics |
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| CN115737495A (en) * | 2022-10-26 | 2023-03-07 | 现代百朗德生物科技(江苏)有限公司 | Siji flower essence extracting solution with anti-inflammatory, antioxidant, whitening and anti-wrinkle effects and preparation method thereof |
| CN115869225A (en) * | 2022-10-26 | 2023-03-31 | 现代百朗德生物科技(江苏)有限公司 | Peach-red four-ingredient soup cosmetic composition with whitening, antioxidant and anti-wrinkle effects and application of peach-red four-ingredient soup cosmetic composition in cosmetics |
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