CN107737061A - A kind of cosmetic composition and preparation method thereof - Google Patents
A kind of cosmetic composition and preparation method thereof Download PDFInfo
- Publication number
- CN107737061A CN107737061A CN201710841269.6A CN201710841269A CN107737061A CN 107737061 A CN107737061 A CN 107737061A CN 201710841269 A CN201710841269 A CN 201710841269A CN 107737061 A CN107737061 A CN 107737061A
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- China
- Prior art keywords
- extract
- root bark
- cosmetic composition
- aloe
- dried tremella
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention discloses a kind of cosmetic composition and preparation method thereof, cosmetic composition is made up of moutan root bark extract, dried tremella extract, aloe extract and cosmetic base, the weight of moutan root bark extract is 5 10% than content, the weight of dried tremella extract is 1 5% than content, the weight of aloe extract is 1 5% than content, and surplus is cosmetic base.Advantages of the present invention:By abolishing cell membrane using biological enzyme, the extraction efficiency of active component in moutan root bark is greatly improved, operability is good, the glycoside material in moutan root bark can effectively be extracted, and retain Polyphenols and Flavonoid substances therein to greatest extent, be advantageous to suppress the growth of skin surface bacterium and fungi, acted synergistically with the aloe extract with efficient whitening anti-aging effect and dried tremella extract so as to reach efficient whitening anti-aging compound action, and quality is gentle, easily absorb, it is non-stimulated, meet requirement of the people to cosmetics safety validity, have a extensive future.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of cosmetic composition and preparation method thereof.
Background technology
Moutan root bark be it is a kind of have clearing heat and detoxicating, cool blood is picked up from Ranunculaceae by the traditional Chinese medicine of the multiple efficacies such as the stasis of blood
The root skin of plant tree peony, modern study, contained paeonol and its glucosides constituents in addition have antiinflammatory action.It lives in plant
Property the research and development of material cosmetics in application prospect it is also more and more wide.
White fungus has the function that enriching yin rich in natural plant colloid and plant polyose, additional its, there is extraordinary moisturizing
Effect.And aloe just has good beauty functions since ancient times, the anthraquinones such as its aloin having are anti-oxidant and whitening
Effect is stronger, can effectively remove the DPPH in skin, have the function that anti-aging.Cosmetic combinations of the prior art
Thing generally all uses chemical products and solvent etc. to be processed production for raw material, and security is relatively low, easily skin is caused to stimulate,
And maintain, care action is more single.
The content of the invention
The defects of for prior art and deficiency, it is an object of the invention to provide a kind of safety, active material extraction effect
The high cosmetic composition of rate.
To achieve the above object, the technical solution adopted by the present invention is:A kind of cosmetic composition, its innovative point be,
It is made up of moutan root bark extract, dried tremella extract, aloe extract and cosmetic base, the weight of the moutan root bark extract
Amount is 5-10% than content, and the weight of the dried tremella extract is 1-5% than content, and the weight of the aloe extract compares content
For 1-5%, surplus is cosmetic base.
It is a further object to provide a kind of preparation method of preceding described cosmetic composition, its innovative point exists
In being made by the steps to obtain cosmetic composition:
(1) high-quality moutan root bark raw material is chosen, 100-200 mesh is crushed to medicinal material pulverizer, the medicinal material crushed is added
Enter 8-10 times of solvent, after addition 0.1%-0.3% cellulases heat 2-3h in 40-50 DEG C of water-bath, in 85 DEG C of -95 DEG C of temperature
Lower inactivation 20-30min, big molecular impurity is removed from the membrane filtration that relative molecular weight is 1000-2000, filtrate is tree peony
Root extract;
(2) choose high-quality aloe raw material and add 3-5 times of solvent in 40-60 DEG C of Microwave Extraction 20-40min, using filter paper mistake
Filter, filtrate is aloe extract;
(3) 4-8 times of solvent is added after white fungus is cleaned up 2h is heated in 60-80 DEG C of water-bath, filtered, filtered using filter paper
Liquid is dried tremella extract;
(4) moutan root bark extract, aloe extract, dried tremella extract and cosmetic base are measured by formula, dissolving is mixed
It is fitted into after even in the bottle sterilized and obtains product.
Further, the solvent in the step (2) is deionized water or 1,3 butanediols of joint or propane diols or dipropyl two
One kind in alcohol.
The present invention has the beneficial effect that:
The extraction effect of active component in moutan root bark is greatly improved by abolishing cell membrane using biological enzyme in the present invention
Rate, operability is good, can effectively extract the glycoside material in moutan root bark, and retain Polyphenols therein to greatest extent
And Flavonoid substances, be advantageous to suppress the growth of skin surface bacterium and fungi, with the reed with efficient whitening anti-aging effect
Luxuriant growth extract and dried tremella extract synergy are so as to reach efficient whitening anti-aging compound action, and quality is gentle, easily inhales
Receive, it is non-stimulated, meet requirement of the people to cosmetics safety validity, have a extensive future.
Brief description of the drawings
Fig. 1 is 503nhibiting concentration measuring and calculating figure;
Fig. 2 is to suppress tyrosinase activity result figure;
Fig. 3 is the Scavenging activity experimental configuration table of free radical;
Fig. 4 is the Scavenging activity absorbance test result figure of free radical;
Fig. 5 is the Scavenging activity result table of free radical.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, below in conjunction with embodiment pair
The present invention is further elaborated.It should be appreciated that embodiment described herein is only to explain the present invention, and
It is not used in the restriction present invention.
Embodiment 1
Present embodiment discloses a kind of cosmetic composition, by moutan root bark extract, dried tremella extract, aloe
Extract and cosmetic base composition, the weight of the moutan root bark extract are 5% than content, the weight of the dried tremella extract
Amount is 1% than content, and the weight of the aloe extract is 1% than content, and surplus is cosmetic base.By in moutan root bark
Glycoside material acted synergistically with the aloe extract with efficient whitening anti-aging effect and dried tremella extract so as to reaching
Efficient whitening anti-aging compound action, and quality is gentle, easily absorbs, it is non-stimulated, meet people to cosmetics safety validity
Requirement, have a extensive future.
Embodiment 2
Present embodiment discloses a kind of cosmetic composition, by moutan root bark extract, dried tremella extract, aloe
Extract and cosmetic base composition, the weight of the moutan root bark extract are 7.5% than content, the dried tremella extract
Weight is 2.5% than content, and the weight of the aloe extract is 2.5% than content, and surplus is cosmetic base.With embodiment
Compare, by increasing the dosage of active principle, effect is remarkably reinforced, and it is real to suppress tyrosinase activity experiment inhibiting rate
Apply example 1 1.5 times.
Embodiment 3
Present embodiment discloses a kind of cosmetic composition, by moutan root bark extract, dried tremella extract, aloe
Extract and cosmetic base composition, the weight of the moutan root bark extract are 10% than content, the dried tremella extract
Weight is 5% than content, and the weight of the aloe extract is 5% than content, and surplus is cosmetic base.Compared with embodiment
Compared with by increasing the dosage of active principle, effect is remarkably reinforced, and it is embodiment to suppress tyrosinase activity experiment inhibiting rate
1.7 times of 1.
Embodiment 4
Present embodiment discloses a kind of preparation method of cosmetic composition, being made by the steps
Cosmetic compositions:
(1) high-quality moutan root bark raw material is chosen, 100-200 mesh is crushed to medicinal material pulverizer, the medicinal material crushed is added
Enter 8-10 times of solvent, after addition 0.1%-0.3% cellulases heat 2-3h in 40-50 DEG C of water-bath, in 85 DEG C of -95 DEG C of temperature
Lower inactivation 20-30min, big molecular impurity is removed from the membrane filtration that relative molecular weight is 1000-2000, filtrate is tree peony
Root extract;
(2) choose high-quality aloe raw material and add 3-5 times of solvent in 40-60 DEG C of Microwave Extraction 20-40min, using filter paper mistake
Filter, filtrate is aloe extract;
(3) 4-8 times of solvent is added after white fungus is cleaned up 2h is heated in 60-80 DEG C of water-bath, filtered, filtered using filter paper
Liquid is dried tremella extract;
(4) moutan root bark extract, aloe extract, dried tremella extract and cosmetic base are measured by formula, dissolving is mixed
It is fitted into after even in the bottle sterilized and obtains product.
Feasible, the solvent in the step (2) is deionized water or 1,3 butanediols of joint or propane diols or DPG
In one kind.
By abolishing cell membrane using biological enzyme, the extraction efficiency of active component in moutan root bark is greatly improved, can grasp
The property made is good, can effectively extract the glycoside material in moutan root bark, and retains Polyphenols and flavones therein to greatest extent
Class material, be advantageous to suppress the growth of skin surface bacterium and fungi.
Embodiment 5
This specific embodiment is disclosed using the cosmetics suppressed in tyrosinase activity experimental test specific embodiment 1-4
The method of the impact of performance of composition.
From the cosmetic composition that the method in specific embodiment 4 is prepared as test raw material, using following step
Suddenly tested,
(1) enzyme concentration selects:
A small amount of enzyme is taken, with buffer solution, color brown;1.5ml centrifuge tubes are taken to add (TYR (0.3mg/ml)
The μ L of 500 μ L+ buffer solutions, 500 μ L+ water, 450 μ L+ enzymes 50);Before enzyme-added, 37 DEG C, 20min;After enzyme-added, 37 DEG C, (enzyme-added-test)
At 10min spectrophotometer wavelength 480nm, absorbance is surveyed.Enzyme concentration is adjusted, makes absorbance (ABS) between 0.45-0.55.
The enzyme of this concentration is as experiment enzyme liquid.
(2) experiment addition
4 groups of contrast experiments are divided to carry out the absorbance under test 480nm, 4 groups of contrast experiments are respectively S, SB, C and CB.S groups
Component be 500 μ L TYR (0.3mg/ml), 500 μ L buffer solution, 450 μ L samples dilutions and 50 μ L enzymes.Wherein
Sample liquid is diluted from 0 μ L, 100 μ L, 200 μ L and 300 μ L amount respectively and is tested absorbance.The component of SB groups is 500 μ L's
TYR (0.3mg/ml), 500 μ L buffer solution, 450 μ L samples dilutions and 50 μ L buffer solutions.Wherein sample liquid is selected respectively
Diluted with 0 μ L, 100 μ L, 200 μ L and 300 μ L amount and test absorbance.The component of C groups is 100 μ L TYR
(0.3mg/ml), 500 μ L buffer solution, 450 μ L samples dilutions and 50 μ L enzymes.Wherein sample liquid respectively from 0 μ L, 100 μ L,
The dilution of 200 μ L and 300 μ L sample and solvent mixed liquor simultaneously tests absorbance.The component of CB groups is 100 μ L TYR
(0.3mg/ml), 500 μ L buffer solution, 450 μ L samples dilutions and 50 μ L buffer solutions.Wherein sample liquid respectively from 0 μ L,
100 μ L, 200 μ L and 300 μ L sample and the dilution of solvent mixed liquor simultaneously test absorbance.
503nhibiting concentration IC is calculated by drawing form50, it is the chart drawn in this specific embodiment referring to Fig. 1,
It is the compound suppression tyrosinase activity result figure of tree peony root aloe white fungus in the present embodiment referring to Fig. 2.It is male by can be calculated
The compound IC for suppressing tyrosinase of red root aloe white fungus50Value is about 744 μ g/ml.Tree peony root aloe is demonstrated by book experiment
When white fungus is compounded in content and is more than or equal to 744 μ g/ml, skin whitening, this product can be haveed the function that by suppressing tyrosinase
The compound addition of tree peony root aloe white fungus is more than 744 μ g/ml, therefore is acted on good skin-whitening.
Embodiment 5
The product that this specific embodiment is disclosed in embodiment 1-4 is tested for the Scavenging activity of free radical.
Specifically, carry out experiment test using following steps:
First, reagent prepares
1st, 3.943mgDPPH is settled to 50mL with 95% ethanol.
2nd, 10mg or so Trolox are settled to 100mL with 95% ethanol.
2nd, experimental procedure
(1) UV schools zero, 95% ethanol are as shown in Figure 3 as blank sample, allocation list;
The ethanol of (2) 500 μ L DPPH+1000 μ L 95%, 10s is shaken, stand 10min, absorbance is surveyed twice, such as following table
Shown in 4.
With reference to Fig. 5 result figure, it is known that, the product in above-described embodiment can produce preferably clear make to free radical
With.
It is described above, it is merely illustrative of the technical solution of the present invention and unrestricted, those of ordinary skill in the art are to this hair
The other modifications or equivalent substitution that bright technical scheme is made, without departing from the spirit and scope of technical solution of the present invention,
It all should cover among scope of the presently claimed invention.
Claims (4)
1. a kind of cosmetic composition, it is characterised in that by moutan root bark extract, dried tremella extract, aloe extract and change
Cosmetic matrix forms, and the weight of the moutan root bark extract is 5-10% than content, and the weight ratio of the dried tremella extract contains
Measure as 1-5%, the weight of the aloe extract is 1-5% than content, and surplus is cosmetic base.
2. a kind of cosmetic composition according to claim 1, it is characterised in that peony root extractive, aloe extract
It is more than 744 μ g/ml with the compound addition of dried tremella extract.
3. a kind of preparation method of cosmetic composition as claimed in claim 1, it is characterised in that be made by the steps
Obtain cosmetic composition:
(1) high-quality moutan root bark raw material is chosen, 100-200 mesh is crushed to medicinal material pulverizer, the medicinal material crushed is added into 8-
10 times of solvents, after addition 0.1%-0.3% cellulases heat 2-3h in 40-50 DEG C of water-bath, gone out at a temperature of 85 DEG C -95 DEG C
20-30min living, big molecular impurity is removed from the membrane filtration that relative molecular weight is 1000-2000, filtrate is that tree peony root carries
Take thing;
(2) choose high-quality aloe raw material and add 3-5 times of solvent in 40-60 DEG C of Microwave Extraction 20-40min, filtered, filtered using filter paper
Liquid is aloe extract;
(3) 4-8 times of solvent is added after white fungus is cleaned up 2h is heated in 60-80 DEG C of water-bath, filtered using filter paper, filtrate is
For dried tremella extract;
(4) moutan root bark extract, aloe extract, dried tremella extract and cosmetic base are measured by formula, after dissolving mixes
It is fitted into the bottle sterilized and obtains product.
4. the preparation method of a kind of cosmetic composition according to claim 3, it is characterised in that in the step (2)
Solvent for deionized water or combine one kind in 1,3 butanediols or propane diols or DPG.
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Cited By (4)
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CN108721192A (en) * | 2018-09-06 | 2018-11-02 | 厦门洋妈制生物科技有限公司 | A kind of extracted form natural plant essence facial mask liquid and its extraction process |
CN111603404A (en) * | 2020-06-29 | 2020-09-01 | 胡以亮 | Skin care essence containing cell extracting solution and preparation method thereof |
CN113855599A (en) * | 2021-10-28 | 2021-12-31 | 济南泽润生物科技有限公司 | Whitening anti-inflammatory peony extract, preparation method thereof and application thereof in cosmetics |
CN114099391A (en) * | 2021-12-28 | 2022-03-01 | 现代百朗德生物科技(江苏)有限公司 | Cosmetic composition with whitening, moisturizing and antioxidant effects and preparation method thereof |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108721192A (en) * | 2018-09-06 | 2018-11-02 | 厦门洋妈制生物科技有限公司 | A kind of extracted form natural plant essence facial mask liquid and its extraction process |
CN108721192B (en) * | 2018-09-06 | 2021-08-20 | 厦门洋妈制生物科技有限公司 | Natural plant extract essence facial mask liquid and extraction process thereof |
CN111603404A (en) * | 2020-06-29 | 2020-09-01 | 胡以亮 | Skin care essence containing cell extracting solution and preparation method thereof |
CN111603404B (en) * | 2020-06-29 | 2021-05-11 | 高宝化妆品(中国)有限公司 | Skin care essence containing cell extracting solution and preparation method thereof |
CN113855599A (en) * | 2021-10-28 | 2021-12-31 | 济南泽润生物科技有限公司 | Whitening anti-inflammatory peony extract, preparation method thereof and application thereof in cosmetics |
CN113855599B (en) * | 2021-10-28 | 2023-06-23 | 济南泽润生物科技有限公司 | Whitening anti-inflammatory peony extract, preparation method thereof and application thereof in cosmetics |
CN114099391A (en) * | 2021-12-28 | 2022-03-01 | 现代百朗德生物科技(江苏)有限公司 | Cosmetic composition with whitening, moisturizing and antioxidant effects and preparation method thereof |
CN114099391B (en) * | 2021-12-28 | 2024-04-12 | 现代百朗德生物科技(江苏)有限公司 | Cosmetic composition with whitening, moisturizing and antioxidation effects and preparation method thereof |
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