CN110507582A - A kind of anti-ageing remediation composition and its preparation method and application containing composite vegetables extractive - Google Patents
A kind of anti-ageing remediation composition and its preparation method and application containing composite vegetables extractive Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/9789—Magnoliopsida [dicotyledons]
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
The invention belongs to cosmetic fields, relate particularly to a kind of composition and its preparation method and application with anti-aging and repair cell effect.Composition according to parts by weight, composite vegetables extractive 10-50 parts by weight, deep-sea fish collagen peptide 5-20 parts by weight, tremella polysaccharides 0.05-7 parts by weight.Composite vegetables extractive, joint deep-sea fish collagen peptide, the tremella polysaccharides factor in the present invention, compounding of the three under certain proportion, it is concured from aquation, barrier function, oxidation and impaired inflammation etc., coordinate synergy, promote microcirculation, eliminate free radical, inhibit oxidation reaction, accelerate skin metabolism, promote collagen synthesis etc. achievees the purpose that anti-aging, repairs damaged cell.Have effects that good beautifying face and moistering lotion, skin whitening, skin care.Preparation method of the invention is simple, is easy to be compounded into cosmetics with other compositions, forms functional skin care item, plays its effect.
Description
Technical field
The invention belongs to cosmetic fields, relate particularly to a kind of composition with anti-aging and repair cell effect
And its preparation method and application.
Background technique
With age, under the action of human senility intrinsic physiological mechanism, by intrinsic aging and exogenous old
Change leads to skin gradually aging.Intrinsic aging is influenced by everyone inherent cause, and extrinsic aging main receptor 1 activity oxygen,
The influence of the environmental factors such as free radical causes skin collagen and cellular matrix to be degraded.Simultaneously as skin is directly and external environment
Contact, the stimulation vulnerable to factors such as substances various in environment, rays, it is easy to come to harm, so that Skin Cell is impaired, directly
Connect the beauty for affecting human body.
Skin aging is usually embodied in skin elasticity reduction, generation wrinkle etc..Skin injury is mainly reflected in skin
The missing of intracellular water, the accumulation of metabolic waste, increase, loss of intracellular nutritional substance of free radical etc. in skin.It is existing
Have in technology, there is the relevant report of more anti-aging, whitening maintenance product, such as patent CN1061093628 discloses one kind
Anti-apolexis composition, anti-aging cosmetics and preparation method thereof, are compounded by plant extracts, predominantly prevent skin aging simultaneously
Firm skin, but the skin damage cell due to caused by environmental factor can not be repaired, and directly cannot supplement institute for Skin Cell
Need nutrient.Patent CN108272712A discloses a kind of anti-aging plant extract composition and its answering in cosmetics
With the function plant extracts collocation in the patent is more brief, and in order to enhance the anti-aging effects of composition, additionally adds
Other anti-aging microelements are added, have kept its composition effect indefinite.
Currently on the market for anti-aging, repair skin skin care item and related raw material it is various, some skin care item may be by
It is not up to standard in material quality or compatibility is unreasonable, function and effect be not it is particularly evident, it is excessively single or excessively complicated at being grouped as.
Therefore it is reliable, comprehensively anti-ageing with can targetedly play that a kind of relatively easy component, element clear efficacy, performance safety are found
Always, the composition for repairing damaged cell is very necessary.
Summary of the invention
The present invention provides a kind of anti-ageing remediation composition and its preparation method and application containing composite vegetables extractive.
To achieve the above object, technical solution of the present invention is as follows:
A kind of anti-ageing remediation composition containing composite vegetables extractive, according to parts by weight, composite plant extracts composition
Object 10-50 parts by weight, deep-sea fish collagen peptide 5-20 parts by weight, tremella polysaccharides 0.05-7 parts by weight.
It is preferred that composition is according to parts by weight, and composite vegetables extractive 15-40 parts by weight, deep-sea fish collagen peptide 8-
15 parts by weight, tremella polysaccharides 0.5-6 parts by weight.
The composition three cooperates with collocation, is effectively improved aquation, barrier function, oxidation and the damage of skin
The effect of the skin physiologies such as inflammation plays the role of comprehensive anti-aging, repairs skin to reach synergistic effect.
The composition is dispersed in basic components, and basic components and composition are mixed in 2-6:1-5 ratio；Its
In, basic components are one or more of pentanediol, butanediol, pure water.
It is preferred that the basic components are the pentanediol and butanediol that mass ratio is 1-5:3-10.
From the foregoing, it can be seen that the composition is other than after three's substance, it further include basic components, the anti-aging,
The cell repair factor is dispersed in basic components.
The composite vegetables extractive is ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur extract, centella extraction
Object, hamamelis extract, Saussurea involucrata extract, emblic extract, angelica extract, Bilberry fruit P.E mass ratio be 1-10:
1-10:1-10:1-10:1-10:1-10:1-10:1-10:1-10:1-10。
Wherein, ginkgo biloba extract object contains GINKGO BILOBA EXTRACT, ginkgoterpene lactone.GINKGO BILOBA EXTRACT can induce antioxidase GCLC's
Expression, and superoxide anion and hydroxy radical can be directly removed, there is promoting blood circulation, activating cell, anti-aging, radical ion to capture
Agent promotes skin collagen to generate, restores the functions such as skin elasticity, antiallergy, anti-inflammatory, whitening.Its master of Radix Paeoniae Alba medicament extract
Want ingredient Paeoniflorin can make skin keep it is delicate, moisten it is smooth, have good skin nutrition, prevent wrinkle, delay body group
The functions such as the aging knitted are a kind of excellent skin-whitening agents.Kapur extract has the function of dredging the channel, nourishing qi and blood
Effect, while active constituent can be made to infiltrate into rapidly subcutaneously, thus the effect of reaching Transdermal absorption.Kapur can be obviously promoted wound
Healing increases granulation tissue structure and reepithelialization, repairs skin accessory organ and has stronger Wound Healing.
Gotu Kola P.E is a kind of heteroside, mainly plays adjustment effect on three levels, first by controlling and adjusting and exempt from
The related inflammation transfer medium of epidemic disease-excitation inhibits skin chronic inflammation, amplifies circulation automatically secondly by decaying inflammation, again
The natural renovation for balancing them makes keratinocyte hyperproliferative normalization, finally by the table of phoirocyte collagen
It reaches, reconstructs corium extracellular matrix.Hamamelis extract has the fat secretion of mitigation oily skin and the skin of allergy
Very excellent effect has and releives, and restrains, the significant effect of antibacterial.Witch hazel repairs impaired flesh for purifying pore
Skin effectively adjusts the pore of diastole, hence it is evident that convergence enlarged pores prevent blackhead, acne from generating.Saussurea involucrata extract contain flavonoids,
Coumarins, Anthraquinones and sesquiterpenoids have the heap of enhancing blood circulation, anti aging effect, anti-wrinkle and lipid
Product improves microcirculation, makes the effects of skin is rich in gloss.Emblic extract is mainly polysaccharide from Phyllanthus Emblica L, tired with significantly resisting
The pharmacological actions such as labor, anti-oxidant, anti-aging, Whitening, spot, antiatherosclerosis, hypoglycemic, reducing blood lipid, liver protection, antibacterial.When
Return extract containing Ligustilide, n-butene acyl lactone, ferulic acid, niacin, sucrose and a variety of amino acid and sesquiterpenoids chemical combination
Object etc..Cholinolytic, effect that is anti-oxidant and removing free radical, can expand capillary of skin, accelerate blood circulation.Radix Angelicae Sinensis is containing rich
Rich microelement, energy skin nutrition, prevents coarse.The preferred whortle of Bilberry fruit P.E is a kind of darkviolet fruit, is rich in
Anthocyanidin has extremely strong antioxidation.Anthocyanidin is a kind of biological flavone, has antioxidant action.Contained by whortle
Some anthocyanidin contents come out at the top among fruit and vegetables, and the most abundant part of anthocyanidin is exactly in its distinctive purple fruit
Skin zone position.
The deep-sea fish collagen peptide is the mixture of jewfish Isin glue collagen peptide and gadus collagen peptide, mass ratio
For 0.5-5:1-10.
It is preferred that the deep-sea fish collagen peptide is the mixture of jewfish Isin glue collagen peptide and gadus collagen peptide,
Mass ratio is 2-5:5-10.
Wherein, Isin glue collagen peptide glue is a kind of high molecular functional protein, it is that the chief component of skin accounts for
The specific gravity of dermal layer of the skin 80%.Deep-sea fish collagen peptide have water lock water storage, it is crease-resistant prolong decline, smooth microgroove, remove spots,
The effects of enhancing skin tone, promotion cell metabolism, delaying cell aging.
The tremella polysaccharides are from Tremella fructification or the resulting polysaccharide of the fermented liquid of tremella steamed stuffed bun.
The tremella polysaccharides are the mixture of tremella polysaccharides A and tremella polysaccharides B, and the mass ratio of the two is 0.05-1:0.02-
5；Wherein, the molecular weight of tremella polysaccharides A is 1000kDa-2000kDa, and the molecular weight of tremella polysaccharides B is less than or equal to 100kDa.
The tremella polysaccharides are the mixture of tremella polysaccharides A and tremella polysaccharides B, and the mass ratio of the two is 0.25-1:0.1-
5；Wherein, the molecular weight of tremella polysaccharides A is 1200kDa-1500kDa, and the molecular weight of tremella polysaccharides B is 10kDa-50kDa.
A kind of above-mentioned acid heteroglycan of tremella polysaccharides, the gained from Tremella fructification or tremella steamed stuffed bun fermentation liquid.Tremella is more
Sugar has the function of improving immunity of organisms and promotes leucocyte, and has brilliant moisturizing water lock ability, has and repairs table
Skin increases the function of epidermis water content, improves cuticula moisture content, the barrier function of the high skin of energy.And have good
Lubricity and film forming, high molecular tremella polysaccharides can skin surface formed one layer of uniform film, i.e., skin protect
Cover makes skin have good smooth feeling and moist feeling, does not shrink not tight, plays a protective role to skin.And it is low molecular
Tremella polysaccharides have good moisture-retaining capacity, are easily absorbed by Skin Cell, improve skin immunity, can provide to skin deep
The effect of layer moisturizing.The tremella polysaccharides are the mixture of tremella polysaccharides A and tremella polysaccharides B comprising 2 kinds of different molecular weights.
Thus the tremella polysaccharides of two kinds of different molecular weights are used in compounding, and can be played moisturizing water conservation in skin surface and deep layer simultaneously and be resisted
Aging and repair.
A kind of application of the anti-ageing remediation composition containing composite vegetables extractive, the composition is as functional skin care
Application in active constituent；Wherein, active constituent accounts for the 12-40wt% of functional skin care total amount.
The present composition can solve skin from various aspects such as replenishing water and preserving moisture, barrier action, oxidation and impaired inflammation
The reason of aging, plays comprehensive anti-aging, cell repair effect.Anti-ageing reparation of the present invention containing composite vegetables extractive
Composition can be used in functional skin-protection product, and the functionality skin-protection product includes facial mask, Essence, lotion, face cream, shield
Hand frost, body lotion, facial cleanser etc..
Advantageous effects of the invention are as follows:
Composite vegetables extractive is that ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur extract, centella mention in the present invention
The mixture of object, hamamelis extract, Saussurea involucrata extract, emblic extract, angelica extract, Bilberry fruit P.E is taken, is combined
Deep-sea fish collagen peptide, the tremella polysaccharides factor, compounding of the three under certain proportion, from aquation, barrier function, oxidation
Effect and impaired inflammation etc. concur, and coordinate synergy, promote microcirculation, eliminate free radical, inhibit oxidation reaction, accelerate skin
Skin metabolism, promotion collagen synthesis etc. achieve the purpose that anti-aging, repair damaged cell.With good beauty
The effect of beauty treatment, skin whitening, skin care.Preparation method of the invention is simple, is easy to be compounded into cosmetics with other compositions
In, functional skin care item are formed, its effect is played.
Specific embodiment:
The present invention provides the anti-ageing remediation composition containing composite vegetables extractive, including anti-aging, the cell repair factor,
Saturating, deep-sea fish collagen peptide and tremella polysaccharides form by composite vegetables extractive for the anti-aging, the cell repair factor.Its
In, composite vegetables extractive is that ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur extract, Gotu Kola P.E, witch hazel mention
The mixture of object, Saussurea involucrata extract, emblic extract, angelica extract, Bilberry fruit P.E is taken, deep-sea fish collagen peptide is
The mixture of jewfish Isin glue collagen peptide and gadus collagen peptide, tremella polysaccharides are the tremella polysaccharides A and silver of different molecular weight
The mixture of fungus polysaccharides B.
Further, ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur extract, Gotu Kola P.E, witch hazel are extracted
Object, Saussurea involucrata extract, emblic extract, angelica extract, Bilberry fruit P.E mass ratio be 1-10:1-10:1-10:1-
10:1-10:1-10:1-10:1-10:1-10:1-10.In the specific embodiment of the invention, ginkgo biloba extract, white peony are extracted
Object, kapur extract, Gotu Kola P.E, hamamelis extract, Saussurea involucrata extract, emblic extract, angelica extract,
The mass ratio of Bilberry fruit P.E is 1:1:1:1:1:1:1:1:1,1:10:1:10:1:10:1:10:1,5:5:5:5:5:10:10:
10:10,1:1:1:1:1:5:5:5:5,1:5:3:4:7:6:8:5:2,5:6:5:2:7:4:9:2:5,3:5:4:2:8:4:9:10:
7,10:6:5:1:8:4:6:8:4.
Each plant extracts, it is by masses' cognition, effective medicinal part of each plant is pre- by removal of impurities, screening, crushing etc.
Processing extracts according to green solvent and extracts acquisition with enzyme assisted extraction method.
Further, the mass ratio of jewfish Isin glue collagen peptide and gadus collagen peptide is in deep-sea fish collagen peptide
0.5-5:1-10, preferably 2-5:5-10.In the specific embodiment of the invention, jewfish Isin glue collagen peptide and gadus collagen egg
The mass ratio 2:5,1:5,3:5,3:8,3:10,4:5,4:7,4:9,1:1,5:8,1:2 of white peptide.
The deep-sea fish collagen peptide is extracted as choosing fish head, fish-skin (squama) and the fish-bone of deep-sea fish as raw material,
It is clean using sterile water wash, the raw material after cleaning crush in investment enzyme digestion reaction tank, carry out heat preservation enzymatic hydrolysis, then
High temperature enzyme deactivation is living；Using active carbon smelling removal, centrifuging and taking supernatant obtains deep-sea fish collagen peptide.
Further, the mass ratio of the A of tremella polysaccharides and tremella polysaccharides B are 0.05-1:0.02-5, preferably 0.25-1:
0.1-5.In the specific embodiment of the invention, the mass ratio of the A and tremella polysaccharides B of tremella polysaccharides is 0.25:0.1,0.25:1,
0.25:3,0.25:5,0.5:1,0.5:3,0.5:5,1:0.1,1:0.5,1:1,1:3,1:5.
The tremella polysaccharides are through ethanol precipitation and to filter from the fermentation liquid of Tremella fructification or tremella steamed stuffed bun, obtain tremella
Polysaccharide crude dissolves crude product with water, and dilute hydrochloric acid acidolysis is added, obtains acid hydrolysis solution, acid hydrolysis solution activated carbon adsorption is filtered
Filtrate adjusts filtrate pH to alkalinity, filters again after processing, obtain refined filtration liquid through 0.22 micron of filter core refined filtration, sunk with ethyl alcohol
Shallow lake refined filtration liquid simultaneously washs precipitating with ethyl alcohol repeatedly, and the precipitating after washing is dried in vacuo and arrives tremella polysaccharides.At acidolysis
The length of time of reason obtains low, high molecular weight tremella polysaccharides product.
Further, the dosage relation of composite vegetables extractive, deep-sea fish collagen peptide and tremella polysaccharides are as follows: compound plant
Object extract 10-50 parts by weight, deep-sea fish collagen peptide 5-20 parts by weight, tremella polysaccharides 0.05-7 parts by weight.Preferably, resist
Dosage of each component in senile cell reparative factor are as follows: composite vegetables extractive 15-40 parts by weight, deep-sea fish collagen peptide 8-15
Parts by weight, tremella polysaccharides 0.5-6 parts by weight.In a certain specific embodiment of the present invention, 15 parts by weight of composite vegetables extractive,
8 parts by weight of deep-sea fish collagen peptide, 0.5 parts by weight of tremella polysaccharides.In a certain specific embodiment of the present invention, composite plant
15 parts by weight of extract, 8 parts by weight of deep-sea fish collagen peptide, 6 parts by weight of tremella polysaccharides.In a certain specific embodiment party of the present invention
In formula, 15 parts by weight of composite vegetables extractive, 15 parts by weight of deep-sea fish collagen peptide, 0.5 parts by weight of tremella polysaccharides.In this hair
In bright a certain specific embodiment, 15 parts by weight of composite vegetables extractive, 15 parts by weight of deep-sea fish collagen peptide, tremella polysaccharides
6 parts by weight.In a certain specific embodiment of the present invention, 40 parts by weight of composite vegetables extractive, 8 weight of deep-sea fish collagen peptide
Measure part, 0.5 parts by weight of tremella polysaccharides.In a certain specific embodiment of the present invention, 40 parts by weight of composite vegetables extractive, deep-sea
15 parts by weight of Isin glue collagen peptide, 0.5 parts by weight of tremella polysaccharides.In a certain specific embodiment of the present invention, composite plant is mentioned
Take 40 parts by weight of object, 15 parts by weight of deep-sea fish collagen peptide, 6 parts by weight of tremella polysaccharides.In a certain specific embodiment party of the present invention
In formula, 25 parts by weight of composite vegetables extractive, 12 parts by weight of deep-sea fish collagen peptide, 2 parts by weight of tremella polysaccharides.In the present invention
In a certain specific embodiment, 30 parts by weight of composite vegetables extractive, 14 parts by weight of deep-sea fish collagen peptide, tremella polysaccharides 4
Parts by weight.In a certain specific embodiment of the present invention, 34 parts by weight of composite vegetables extractive, 11 weight of deep-sea fish collagen peptide
Measure part, 1.5 parts by weight of tremella polysaccharides.
Further, the anti-ageing remediation composition containing composite vegetables extractive is in addition to anti-aging, the cell repair factor
It outside, further include basic components, the anti-aging, the cell repair factor are dispersed in basic components.The base set
It is divided into pentanediol, butanediol and pure water.Anti-ageing remediation composition of the present invention containing composite vegetables extractive can be used for function
Property skin-protection product in, it is described functionality skin-protection product include facial mask, Essence, lotion, face cream, hand lotion, body lotion, facial cleanser
Deng.Product preparation method is according to each cosmetics conventional method disclosed in the prior art.
Technical solution of the present invention is further elaborated below with reference to embodiment, described embodiment is only this hair
Bright a part of the embodiment, but institute's protection scope of the present invention is without being limited thereto.
Embodiment 1
Anti-ageing remediation composition of the present invention containing composite vegetables extractive is by anti-aging, the cell repair factor and foundation
Composition, the anti-aging, the cell repair factor saturating, deep-sea fish collagen peptide and tremella polysaccharides for composite vegetables extractive,
Foundation is pentanediol, butanediol and pure water.
Anti-ageing remediation composition formula containing composite vegetables extractive is 40 parts by weight of composite vegetables extractive, deep-sea fish glue
Former 15 parts by weight of protein peptides, 0.5 parts by weight of tremella polysaccharides, 3 parts by weight of pentanediol, 5 parts by weight of butanediol, 36.5 parts of pure water；
Wherein composite vegetables extractive is extracted by the ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur of mass ratio 1:1:1:1:1:1:1:1
Object, Gotu Kola P.E, hamamelis extract, Saussurea involucrata extract, emblic extract, angelica extract, Bilberry fruit P.E group
At；Deep-sea fish collagen peptide is made of the jewfish Isin glue collagen peptide and gadus collagen peptide of mass ratio 2:5；Tremella polysaccharides
It is made of the molecular weight 1200kDa-1500kDa tremella polysaccharides A and molecular weight 10kDa-50kDa tremella polysaccharides B of 0.25:0.1.
The above-mentioned anti-ageing remediation composition containing composite vegetables extractive the preparation method comprises the following steps: with pure water by pentanediol, fourth
Glycol, the dissolution of tremella polysaccharides mixture, are warming up to 45-50 DEG C, are uniformly mixed；Sequentially add composite vegetables extractive and depth
Ocean fish collagen peptide mixer, is cooled to room temperature after being uniformly mixed, as the anti-ageing reparation containing composite vegetables extractive
Composition.
Embodiment 2
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is that composite vegetables extractive is mentioned by the ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur of mass ratio 1:5:3:4:7:6:8:5:2
Take object, Gotu Kola P.E, hamamelis extract, Saussurea involucrata extract, emblic extract, angelica extract, Bilberry fruit P.E
Composition.
Embodiment 3
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur of the composite vegetables extractive by mass ratio 3:5:4:2:8:4:9:10:7
Extract, Gotu Kola P.E, hamamelis extract, Saussurea involucrata extract, emblic extract, angelica extract, cowberry are extracted
Object composition.
Embodiment 4
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is that deep-sea fish collagen peptide is made of the jewfish Isin glue collagen peptide and gadus collagen peptide of mass ratio 3:8.
Embodiment 5
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is that deep-sea fish collagen peptide is made of the jewfish Isin glue collagen peptide and gadus collagen peptide of mass ratio 4:7.
Embodiment 6
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is that tremella polysaccharides are more by the molecular weight 1200kDa-1500kDa tremella polysaccharides A and molecular weight 10kDa-50kDa tremella of 0.5:3
Sugared B composition.
Embodiment 7
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is molecular weight 1200kDa-1500kDa tremella polysaccharides A and molecular weight 10kDa-50kDa tremella polysaccharides B of the tremella polysaccharides by 1:1
Composition.
Embodiment 8
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is 15 parts by weight of composite vegetables extractive, 15 parts by weight of deep-sea fish collagen peptide, 0.5 parts by weight of tremella polysaccharides, pentanediol 5
Parts by weight, 4 parts by weight of butanediol, 60.5 parts of pure water.
Embodiment 9
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is 15 parts by weight of composite vegetables extractive, 8 parts by weight of deep-sea fish collagen peptide, 0.5 parts by weight of tremella polysaccharides, pentanediol 7
Parts by weight, 5 parts by weight of butanediol, 64.5 parts of pure water.
Comparative example 1
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is Radix Paeoniae Alba medicament extract, Saussurea involucrata extract, emblic extract, Radix Angelicae Sinensis of the composite vegetables extractive by mass ratio 1:1:1:1
Extract composition.
Comparative example 2
The component of anti-ageing remediation composition, formula and the preparation method is the same as that of Example 1, difference is to mention without composite plant
Take object.
Comparative example 3
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is that deep-sea fish collagen peptide only includes jewfish Isin glue collagen peptide.
Comparative example 4
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is without containing deep-sea fish collagen peptide.
Comparative example 4
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
It only includes the tremella polysaccharides A that molecular weight is 1200kDa-1500kDa that place, which is tremella polysaccharides,.
Comparative example 5
The component of anti-ageing remediation composition containing composite vegetables extractive, formula and the preparation method is the same as that of Example 1, difference
Place is not comprising tremella polysaccharides.
Application examples
The above embodiment of the present invention preparation the anti-ageing remediation composition containing composite vegetables extractive can be used as function at
Point be applied in cosmetics, content in cosmetics can be 5-30wt%, such as 5wt%, 10wt%, 15wt%,
20wt%, 25wt%, 30wt%.
To better illustrate beneficial effects of the present invention, efficacy assessments experiment is carried out to test sample.
Test 1DPPH radicals scavenging experiment
Method: accurately weighing DPPH, is configured to the solution of 0.2mmol/L DPPH, then with pure water that sample of the present invention is dilute
1.0mg/mL is released, sample liquid is obtained.It takes 2 milliliters of 0.2mmol/L DPPH solution to be uniformly mixed, is protected from light stands 30min at room temperature
Afterwards, with absorbance value at ultraviolet specrophotometer measurement 517nm, it is denoted as Aj.2ml is added to steam with 2 milliliters of 0.2mmol/LDPPH solution
Distilled water is stood, and with ultraviolet specrophotometer measurement absorbance value at 517nm, is denoted as Ac.Removing of the sample to DPPH free radical
Rate calculates as follows: DPPH free radical scavenging activity=* 100 parts of [1- (Ai-Aj)/Ac], test result see the table below:
| Group | The clearance rate (%) of DPPH free radical |
| Embodiment 1 | 87.3 |
| Embodiment 2 | 86.5 |
| Embodiment 3 | 86.8 |
| Embodiment 4 | 85.7 |
| Embodiment 5 | 84.6 |
| Embodiment 6 | 83.0 |
| Embodiment 7 | 84.2 |
| Embodiment 8 | 83.8 |
| Embodiment 9 | 84.5 |
| Comparative example 1 | 66.2 |
| Comparative example 2 | 60.3 |
| Comparative example 3 | 62.1 |
| Comparative example 4 | 61.4 |
| Comparative example 5 | 65.8 |
Test the experiment of 2 hydroxyl radical free radical clearance rates
Method: taking the ethanol solution that 1.0mL concentration is the Phen of 1.865mmol/L in test tube with ground stopper, point
Not Jia Ru concentration be 0.2mol/L pH 7.4 each embodiment and comparative example of phosphate buffer 2mL and 1mL it is compound anti-
The FeSO47H2O solution that 1.0mL concentration is 1.865mmol/L is added in anti-aging composition after mixing well, add after mixing again
It is molten to measure each group mixing after 37 DEG C of waters bath with thermostatic control, 60min respectively at 536nm by the H2O2 for entering 1.0mL 0.03% (v/v)
The absorbance value of liquid, obtains A1, replaces sample embodiment and comparative example composition to survey absorbance value as blank group using distilled water, obtains A2,
Using distilled water substitution H2O2 as damage group, surveying its absorbance value is A3, and the clearance rate of the hydroxyl radical free radical of sample presses following public affairs
Formula calculates: hydroxyl radical free radical clearance rate (%)=[(A1-A3)/(A2-A3)] × 100% takes the average value measured three times, detection
As a result as shown in the table.
| Group | Hydroxyl radical free radical clearance rate (%) |
| Embodiment 1 | 84.9 |
| Embodiment 2 | 83.2 |
| Embodiment 3 | 81.6 |
| Embodiment 4 | 82.7 |
| Embodiment 5 | 80.6 |
| Embodiment 6 | 83.4 |
| Embodiment 7 | 80.7 |
| Embodiment 8 | 79.4 |
| Embodiment 9 | 80.1 |
| Comparative example 1 | 58.8 |
| Comparative example 2 | 61.2 |
| Comparative example 3 | 60.0 |
| Comparative example 4 | 57.4 |
| Comparative example 5 | 63.3 |
Test 3 tyrosinase inhibition tests
Method: with the phosphate buffer (PBS) of 0.2mol/L pH=6.8 for solvent, embodiment and comparative example is prepared respectively
Concentration is the solution of 0.2mg/mL.Taking 0.9mL embodiment and comparative example concentration respectively is the solution of 0.2mg/mL, and 1mL L- is added
The phosphate buffer (PBS) of tyrosine (0.3mol) and 1mL pH=6.8 preheats 10 minutes in 37 DEG C of thermostatic water baths, then plus
Enter 0.1ml tyrosinase aqueous solution (1.0mg/ml, mcllvains buffer), is sufficiently stirred, after 37 DEG C are reacted 15 minutes,
It measures 475nm absorbance (D1).In addition, replace the progress of embodiment and comparative example solution same anti-with above-mentioned phosphate buffer
It answers, measures absorbance (D2).In order to compare, under conditions of sample solution and tyrosinase is not added, absorbance (D3) is measured.With
Following formula calculates inhibitory activity against tyrosinase.
Inhibitory activity against tyrosinase (%)=(D2-D1)/(D2-D3) × 100 result is as shown in the table:
| Group | Tyrosinase activity rate (%) |
| Embodiment 1 | 69.5 |
| Embodiment 2 | 66.8 |
| Embodiment 3 | 67.3 |
| Embodiment 4 | 68.6 |
| Embodiment 5 | 66.1 |
| Embodiment 6 | 67.5 |
| Embodiment 7 | 65.8 |
| Embodiment 8 | 66.4 |
| Embodiment 9 | 65.9 |
| Comparative example 1 | 30.7 |
| Comparative example 2 | 28.3 |
| Comparative example 3 | 34.1 |
| Comparative example 4 | 31.2 |
| Comparative example 5 | 29.6 |
Although can be reached by each composition visible in the various embodiments described above and remove free radical effect, and it is scattered in purifying
Effect can be embodied in water；But since each plant extracts passes through different content ratio in the composition of proposition of the embodiment of the present invention
The compounding of example and the deep-sea fish collagen peptide and tremella polysaccharides ingredient of compatibility different content；And composition components are pressed
Certain proportion is dispersed in pure water after mixing with basic components, carries out embodiment respectively and comparative example is tested, Ke Yiming
Aobvious to find out compared with comparative example, function and effect of each embodiment in terms of removing DPPH and hydroxyl radical free radical are more obvious.In addition to
Have and remove free radical effect, equally there is apparent advantage in terms of inhibiting TYR enzyme activity compared to each embodiment of comparative example,
Therefore composition also has effects that bright color Whitening, spot.Composition can be promoted after using the dispersion of composite foundation substance
Skin Cell further improves skin to the utilization rate of composition effective component, promotes skin quality, skin is more preferably fitted
External environment is answered to convert.
The above embodiments are merely illustrative of the technical solutions of the present invention rather than limiting the scope of the invention, the present invention
Protection scope be not limited thereto, anyone skilled in the art in the technical scope disclosed by the present invention,
It is subject to equivalent substitution or change according to the technical scheme of the invention and its inventive conception, should all covers in protection scope of the present invention
Within.
Claims (10)
1. a kind of anti-ageing remediation composition containing composite vegetables extractive, it is characterised in that: composition is according to parts by weight, compound
Plant extracts 10-50 parts by weight, deep-sea fish collagen peptide 5-20 parts by weight, tremella polysaccharides 0.05-7 parts by weight.
2. the anti-ageing remediation composition according to claim 1 containing composite vegetables extractive, it is characterised in that: composition is by weight
Measure number meter, composite vegetables extractive 15-40 parts by weight, deep-sea fish collagen peptide 8-15 parts by weight, tremella polysaccharides 0.5-6 weight
Measure part.
3. the anti-ageing remediation composition as described in claim 1 or 2 containing composite vegetables extractive, it is characterised in that: described group
It closes object to be dispersed in basic components, basic components and composition are mixed in 2-6:1-5 ratio；Wherein, basic components penta
One or more of glycol, butanediol, pure water.
4. the anti-ageing remediation composition as described in claim 1 or 2 containing composite vegetables extractive, it is characterised in that: described multiple
Conjunction plant extracts be ginkgo biloba extract, Radix Paeoniae Alba medicament extract, kapur extract, Gotu Kola P.E, hamamelis extract,
Saussurea involucrata extract, emblic extract, angelica extract, Bilberry fruit P.E mass ratio be 1-10:1-10:1-10:1-10:1-
10:1-10:1-10:1-10:1-10:1-10。
5. the anti-ageing remediation composition as described in claim 1 or 2 containing composite vegetables extractive, it is characterised in that: the depth
Ocean fish collagen peptide is the mixture of jewfish Isin glue collagen peptide and gadus collagen peptide, mass ratio 0.5-5:1-10.
6. the anti-ageing remediation composition as described in claim 1 or 2 containing composite vegetables extractive, it is characterised in that: the depth
Ocean fish collagen peptide is the mixture of jewfish Isin glue collagen peptide and gadus collagen peptide, mass ratio 2-5:5-10.
7. the anti-ageing remediation composition as described in claim 1 or 2 containing composite vegetables extractive, it is characterised in that: the silver
Fungus polysaccharides are from Tremella fructification or the resulting polysaccharide of the fermented liquid of tremella steamed stuffed bun.
8. the anti-ageing remediation composition according to claim 7 containing composite vegetables extractive, it is characterised in that: the tremella is more
Sugar is the mixture of tremella polysaccharides A and tremella polysaccharides B, and the mass ratio of the two is 0.05-1:0.02-5；Wherein, tremella polysaccharides A
Molecular weight is 1000kDa-2000kDa, and the molecular weight of tremella polysaccharides B is less than or equal to 100kDa.
9. the anti-ageing remediation composition according to claim 8 containing composite vegetables extractive, it is characterised in that: the tremella is more
Sugar is the mixture of tremella polysaccharides A and tremella polysaccharides B, and the mass ratio of the two is 0.25-1:0.1-5；Wherein, tremella polysaccharides A
Molecular weight is 1200kDa-1500kDa, and the molecular weight of tremella polysaccharides B is 10kDa-50kDa.
10. a kind of application of the anti-ageing remediation composition described in claim 1 containing composite vegetables extractive, it is characterised in that:
The composition is as the application in functional skin care activity ingredient；Wherein, active constituent accounts for the 12- of functional skin care total amount
40wt%.
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