CN104434731B - Nutritional nourishing hand cream and preparation method thereof - Google Patents
Nutritional nourishing hand cream and preparation method thereof Download PDFInfo
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Abstract
The invention discloses nutritional nourishing hand cream and a preparation method thereof. The hand cream comprises the following components: shea butter, horse oil, wheat germ oil, rose infused oil, snow lotus herb infused oil, myosotis infused oil, universal self-emulsified composite emulsifier, AC-402, 25% triethanolamine, bletilla extract, green tea extract, actinidia chinensis extracted juice, pyracantha fortuneana fruit extracted juice, 1,2-propylene glycol, biological polysaccharide gum, a 20% urea solution, Liponic EG-1, trehalose, nicotinamide, honey, vitamin E, sodium alginate, hydroxypropyl methyl cellulose, a 1% ethylenediamine tetraacetic acid disodium salt solution, a 10% citric acid solution, a 5% ethylparaben solution, distilled water and essence. Compared with the prior art, the hand cream has the advantages of providing rich nutrition to hand skin, deep nourishing dry and rough hands, regulating balance of moisture and oil, softening waste cutin, flattening fine lines, supplying moisture to hands and increasing effects of moistening and whitening.
Description
Technical field
The invention belongs to skin care field is and in particular to a kind of nutrition moist type hand cream and preparation method thereof.
Background technology
Because suffering from the environmental stimulis such as sunlight, pollution, cold for a long time, lead to that hand skin is aging, problem is dried presents
Rejuvenation, the trend generalizing, solve the problems, such as that hand is the embodiment of quality of life lifting.It is known that handss are the second of woman
Open face it is seen that the maintenance of hand skin is extremely important, having the pure white jade hands of a pair of health is the diligent of every people seeking beauty
Pursue.However, we are often required to stand weather, chemicals, work to the next injury of hand strap, but can't buy safely and effectively handguard
Frost, makes people be perplexed by hand problem, is such as dried, peeling, chilblain, skin aging, jaundice etc., these problems make the youth
Beautiful graceful beats heavy discount, be also that life to us brings many puzzlements.
It is special that vegetable polysaccharidess, vitamin and its active component that flowers and fruits class is rich in all has functions that, is natural function
Property cosmetics best raw material, correctly select natural plants, in hand cream add plant essence, water lock barrier mechanism can be set up
Stimulate to correspond to external environment, it is to avoid water loss.Active component specific to every kind of plant can provide multiple for hand skin
Precious nutrient, reduces microgroove and produces, tender white muscle skin, lifts the color and luster of skin and bright sense, gives the nursing of hand skin deep layer.
Using sophisticated technologies, the plant essence composition extracting in natural flowers and fruits adds in hand cream, can improve hand skin comprehensively, reinvent
Plentiful tender fine and slim hands, no matter for fashion men and women or middle-aged and elderly people, using containing natural flowers and fruits elite extract
Moist moisturizing hand cream be all one kind not only scientific and effective but also conveniently skin care method.
Content of the invention
It is an object of the invention to provide a kind of nutrition moist type hand cream, containing natural flowers and fruits plant essence.
It is also an object of the present invention to provide a kind of preparation method of nutrition moist type hand cream.
A kind of nutrition moist type hand cream, in terms of parts by weight, its raw material components and content are:
Described Rhizoma Bletillae extraction solution is to be prepared by the following method:
Weigh the Pseudobulbus Bletillae (Rhizoma Bletillae) appropriate, soak 0.15-1h, be heated to 90-100 DEG C, decoct and extract 3 times, the 1st time plus 6-12 times amount
Water, extracts 0.5-2h, the 2nd time plus 4-10 times amount water, extracts 0.5-1.5h, the 3rd time plus 3-8 times amount water, extracts 0.5-1.5h, often
Secondary filtration, merging filtrate, the volume concentration of filtrate, to 3-6 times of g/ml of Pseudobulbus Bletillae (Rhizoma Bletillae) weight, filters, takes filtrate, obtain final product.
Described green tea extractive liquor is prepared by the following method:
Weigh green tea appropriate, soak 0.15-0.8h, decoct in 90-100 DEG C of heating and extract 3 times, the 1st time plus 6-12 times amount
Water, extracts 0.5-2h, the 2nd time plus 4-10 times amount water, extracts 0.5-1.5h, the 3rd time plus 3-8 times amount water, extracts 0.5-1.5h, often
Secondary filtration, merging filtrate, the volume concentration of filtrate, to 3-6 times of g/ml of green tea weight, filters, takes filtrate, obtain final product.
Described Fructus actinidiae chinensiss juicing is prepared by the following method:
Weigh fresh Fructus actinidiae chinensiss, peeling, stripping and slicing, weigh a certain amount of, put in juice extractor, and add 8-12 times of g/ml's
Distilled water, gained Fructus actinidiae chinensis juice is filtered 3-6 time with double gauze, filters, takes filtrate, obtain final product.
Described pyracantha fortuneana juicing is prepared by the following method:
Weigh fresh pyracantha fortuneana a certain amount of, put in juice extractor, and add the distilled water of 8-12 times of g/ml, gained fire spine
Fruit juice is filtered 3-6 time with double gauze, filters, takes filtrate, obtain final product.
Described Flos Rosae Rugosae is soaked oil and is prepared by the following method:
Weigh dry Flos Rosae Rugosae appropriate, be soaked in 10-18 times of g/ml Semen Maydis oil, soak 12-24h, in 30-60 DEG C of supersound extraction
5-6h, filters, takes filtrate, obtain final product.
Described Herba Saussureae Involueratae soaks oil and is prepared by the following method:
Weigh dry Herba Saussureae Involueratae appropriate, be soaked in 10-18g/ml times of Semen Maydis oil, soak 12-24h, ultrasonic carry in 30-60 DEG C
Take 5-6h, filter, take filtrate, obtain final product.
Described Myosotis sylvatica soaks oil and is prepared by the following method:
Weigh Myosotis sylvatica appropriate, be soaked in 10-18 times of camellia seed oil, soak 12-24h, in 30-60 DEG C of supersound extraction 5-
6h, filters, takes filtrate, obtain final product.
Described essence be rose essence, peach flavor, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence,
One of osmanthus flower fragrance.
A kind of preparation method of nutrition moist type hand cream that the present invention provides, comprises the following steps:
A) weigh sodium alginate 0.01-0.5 part, be dissolved in 1-10 part distilled water, be heated to 60-80 DEG C, stir in heating
Mix, after mix homogeneously, standing makes it fully swelling, obtains sodium alginate soln；
B) weigh hydroxypropyl methyl cellulose 0.01-0.5 part, be scattered in 5-12 part distilled water, be stirred until homogeneous rapidly,
Standing, naturally swelling 5-7h, stand-by；
C) shea butter 0.5-5.0 part, house oil 0.2-5.0 part, Semen Tritici aestivi germ oil 1.0-5.0 part, Flos Rosae Rugosae immersion oil are weighed
1.0-5.0 part, Herba Saussureae Involueratae soak oily 1.0-5.0 part, Myosotis sylvatica soaks oily 1.0-5.0 part, general-purpose self emulsifying mixed emulsifier
Ac-4021.0-5.0 part is placed in keeping temperature 60-90 DEG C heating in water bath melting on water-bath in beaker, as oil phase；
D) weigh distilled water 4.0-50.0 part, 25% triethanolamine solution 1.0-5.0 part, be placed in 60-90 DEG C of heating in water bath,
Obtain aqueous phase；
E) weigh liponic eg-11.0-5.0 part, 1-2 propylene glycol 1.0-5.0 part, 2.0 parts -5.0 parts of biological polyoses glue,
Gonak prepared by sodium alginate soln prepared by step a), step b), is heated to 80-90 DEG C,
Stir, obtain thickening agent；
F) treat that oil phase melts completely, aqueous phase is poured in oil phase, side edged stirs to same direction, in uniform milky
Paste, obtains final product substrate, and substrate is cooled to room temperature；
G) Mel 0.1-2.0 part, trehalose 0.5-5.0 part, nicotiamide 0.01-1.0 part, vitamin e 0.1-1.0 are weighed
Part, 20% urea liquid 1.0-5.0 part, Rhizoma Bletillae extraction solution 0.1-3.0 part, green tea extractive liquor 0.1-3.0 part, pyracantha fortuneana juicing
0.1-3.0 part, Fructus actinidiae chinensiss juicing 0.1-3.0 part, are uniformly mixed, and add in the substrate after cooling, obtain cream mastic；
H) to the thickening agent that the cream mastic addition step e) of step g) gained is made, stirring 10-15min, mix homogeneously,
Add 10% citric acid solution 0.1-5.0 part, adjust ph between 6-7；
I) it is eventually adding 1% disodium ethylene diamine tetra-acetic acid solution 0.01-5.0 part, 5% ethyl hydroxybenzoate alcoholic solution 0.01-
5.0 parts, wherein concentration of alcohol is 75%, and 1% essence 0.01-0.05 part stirs, obtains final product containing natural flowers and fruits plant essence
Nutrition moist type hand cream.
Various composition in the present invention is as follows:
Shea butter is referred to as " liquid golden ", is a kind of fully natural green plant source solid grease, is extremely easy to human body and inhales
Receive, reepithelialization can be promoted, deep layer is moistened, and prevents season cracking, form protecting film in skin surface, moisturizing, sun-proof, anti-
Shield effect is notable.The phytosterol that it contains has the effect of antiinflammatory, antiallergic concurrently for injured skin, and the natural sun-prevention containing becomes
Point-cinnamic acid play the role of suppression formed black tryrosinase, have certain insulating effect to ultraviolet, brown patch can be made to shoal,
Even disappear.Shea butter is because of its superpower antioxidant effect, gently non-stimulated, can keep skin natural elasticity, is for protecting
Shield both hands, the desirable feedstock of Glycerin are it is adaptable to sensitivity skin uses in interior all kinds of babies, child's skin, adult.
The key component of house oil is Oleic acid, linoleic acid and Palmic acid, wherein Oleic acid and linoleic acid total content is 50%.House oil
In the nutrient (vitamin e and linolenic acid) that contains human body health can be recovered and make skin tender, and can strengthen to disease
Immunity and resistance.House oil a small amount of " satisfied fatty acid " forms layer protecting film, its substantial amounts of unsaturation in skin surface
Fatty acid is absorbed by the skin, and participates in the metabolic function of human skin tissue, the reparation of skin damage cell is served very heavy
The effect wanted.
Flos Rosae Rugosae contains volatile oil (Oleum Rosae Rugosae), Quercitroside, amaroid, fat, tannin, multivitamin, glucose, really
The composition beneficial to health such as sugar, lemon drops, has defying age, whitening effect, can effectively remove free radical, eliminates
Pigmentation, makes us calling out and sends out youthful vigor, and life-time service can make skin moisten and be rich in gloss, long-term taking, and cosmetic result is very
Good.Flos Rosae Rugosae extract oil has functions that moisturizing, nourishes, and makes the skin that sensitivity is dried recover water profit in time tender；Have convergence,
Antibacterial and the calm effect releived, the pore that compacts, the excessive fat secretion of suppression, make skin exquisiteness pure and fresh, not bellding light；Rose
Gas can be releived emotion of compacting, and then loosens mood, gives people to feel at ease and happiness, eliminates pressure, lifts U.S. flesh effect further.
Myosotis sylvatica has heat-clearing and toxic substances removing, and clear away heart-fire improving eyesight, enriching yin and nourishing kidney, looks improving and the skin nourishing, the effect of nourishing blood for regulating menstruation, and can promote warp
Body metabolism, delaying cell aging, improves immunocompetence.C containing vitamin, beauty treatment is brightened, it is to avoid the product of wrinkle and black speck
Raw, particularly there is certain elimination to act on freckle, acne.
Herba Saussureae Involueratae is preferable natural antidotal agent, is exactly to treat dermopathic good medicine since ancient times.It contains in Herba Saussureae Involueratae
Fat, Saussurea Polysaccharide, aminoacid, vitamin, sugar, mineral, phytosterin compound, enzyme isoreactivity material.Its sun-proof system
Number is up to 22spf, far above the domestic super-strength ultraviolet radiation of 15spf.Therefore, ultraviolet can effectively be protected the skin from
Infringement, and the rising to lipid peroxide in liver caused by vivotoxin and serum has obvious inhibitory action.Herba Saussureae Involueratae tool is anti-
Effect of inflammation, tissue repair and anti-superoxide radical, is induced freely by physiology or non-physiologic factor (as disease) to defence
Base long-term chronic progressive damages positive effect.This effect, shows as health care when for oral administration and strengthens immunologic function, outward
Used time can reach the purpose of beauty treatment, speckle dispelling, delay skin aging.Herba Saussureae Involueratae grinds soak liquid energy skin nutrition, and can suppress table
Dermatophytes, star exert the dermatophytess such as card bacterium, have preferable therapeutical effect, can also block ultraviolet.Herba Saussureae Involueratae can accelerate skin
Skin metabolism, balances endocrine, naturally removes fiery speckle dispelling, reduces wrinkle, makes skin holding gloss, plentiful, to facial freckle, liver
Speckle etc. has good curative effect.These good characteristics of Herba Saussureae Involueratae are used for skin protection, hair care, skin is had moist, sterilizing, antiinflammatory, granulation promoting,
Sun-proof, soften, smooth and only act in vain.
Biological polyoses glue is a kind of 1% linearly poly polysaccharide viscosity solution, ideally has good sensory advantages simultaneously
And moisture-keeping efficacy, it is best " active excipient "." water suction " ability of sugar strengthens its moisture-keeping efficacy.From the point of view of for a long time,
Biological polyoses glue can provide higher hydration for skin.
Vitamin e is an important antioxidant.The protein active structure of vitamin e energy stabilizing cell membrane, promotes muscle
Normal development and keep skin elasticity, make skin and body maintain vigour.Vitamin e has functions that defying age, enters
Skin Cell can more directly help the infringement to free radical resisting, ultraviolet and pollutant for the skin, prevent skin because some are chronic or
Recessive injury and follow the string until aging, deposition in cell for the lipofuscin can be eliminated simultaneously, improve the normal work(of cell
Can, slow down histiocytic aging course.
Green tea contributes to slow down aging, prevents and treats radiation injury.Contribute to the tea polyphenols tool of beauty and skin care in green tea
There are very strong non-oxidizability and physiologically active, be the scavenger of human free radical, have blocking-up lipid peroxidation, scavenging capacity
The effect of enzyme.Tea polyphenols and its oxidation product have the ability absorbing radioactive substance strontium 90 and Co 60 murder by poisoning.Tea polyphenols are water
Soluble substance, is washed one's face with it and can remove the greasy of face, restrains pore, has sterilization, sterilizing, resisting age of skin, reduces daylight
In ultraviolet radiation to the effects such as the damage of skin.
Fructus actinidiae chinensiss have the effect of the antipyretic, nourishing and fit keeping function that promotes the production of body fluid.It contains the hydrolytic enzyme of thiol proteinase and superoxides discrimination
Change enzyme, there is skin care, enhance immunity, defying age, the work of vessel softening, anti-swollen, inflammation-diminishing function and blacking hair and beauty, tender and lovely skin
With.Contain abundant vitamin a, vitamin c and vitamin e in Fructus actinidiae chinensiss, and there is antioxidation, can effectively brighten skin
Skin, eliminates freckle and skin sore, strengthens the anti-aging ability of skin, strengthening immune system, promotes wound healing, to small pox and acne print
There is suitable curative effect.
Firethorn fruit contains abundant organic acid, protein, aminoacid, vitamin and multiple mineral element.In pyracantha fortuneana
Containing biological whitening substance, can effectively suppress the vigor of various pigment enzymes in human body, make skin not chromogenesises.Some Fructus Pyracanthaes
The women in producing region uses Fructus Pyracanthae juice surface application it is said that whitening effect is fine, and its extracting solution is widely used in cosmetics.
The Pseudobulbus Bletillae (Rhizoma Bletillae) has astringing to arrest bleeding, detumescence and promoting granulation, promotes epithelial cell reparation, directly participates in the reparation of damaged tissues and cell
And metabolic process, therefore have functions that to promote wound healing, defying age, crease-resistant, moisturizing.Pseudobulbus Bletillae (Rhizoma Bletillae) glucomannan is applied to make up
Epithelial cell reparation in conduct industry and wrinkle removal, defying age field.Beta glucan would generally cause macrophage activation, and huge bites
Cell activation can cause a series of reaction, can cause the activation of fibroblast first, thus produce epidermal growth because
Sub (ecgf) and angiogenesis factor (af) skin wrinkling to defying age.Ecgf can promote the life of collagen protein and elastin laminin
Becoming, thus improving skin appearance, smoothing away wrinkles.
Sodium alginate plays good thickening power in cosmetics, can improve the moisture retention of skin, is normal in cosmetics
The thickening agent seen and wetting agent.
Substantial amounts of natural flowers and fruits plant extract component is with the addition of in this hand cream prescription.On the one hand moisten to repair by deep layer
The shield coarse both hands of drying, adjust water and oil balance, thus suppressing mottle wrinkle, preventing the generation of cold injury, chilblain and season cracking.
Numerous compositions in this prescription have comprehensive nutrient and antioxidant content, and such as Radix Arnebiae (Radix Lithospermi), pyracantha fortuneana, Pseudobulbus Bletillae (Rhizoma Bletillae) etc. contain micro unit
Plain selenium, manganese, monounsaturated fatty acid, vitamin a, c, e.Bletilla glucomannan may participate in reparation and the metabolism of damaged tissues or cell
Journey, promotes epithelial cell reparation, the skin ulcer that disappears speckle dispelling.Radix Arnebiae (Radix Lithospermi) can all have reasonable curative effect to cold injury, chilblain.For another example Butyrospermum Parkii
The natural oil energy deep layer such as oil, camellia seed oil, Semen Tritici aestivi germ oil moistens hand skin, smooths microgroove, and it is rich to be that hand skin is brought
Eutrophy, the indices that shea butter secretes oils and fatss with human sebaceous are closest, contain abundant non-saponified composition, easily
In absorption of human body, season cracking can not only be prevented moreover it is possible to recover and keep the natural elasticity of skin further, there is preferable depth
The moist effect of layer, also has the effect of antiinflammatory, antiallergic and anti-ultraviolet concurrently, special add vitamin e and carbamide effectively prevent both hands because
The dry peeling causing, cracking.
On the other hand to supplement sufficient nutrition further through whitening skin and preserving moisture, to beautify hand skin, make the colour of skin fine and smooth, glossy,
Tender white, flexible.As the plant mucilage, mineral, polysaccharide, organic being rich in Flos Rosae Rugosae, Herba Saussureae Involueratae, Myosotis sylvatica, Fructus actinidiae chinensiss, green tea
Acid, vitamin, antioxidant content etc., can keep the skin wet for both hands effectively, skin tight, being dried of releiving, and soften angle of always giving up
Matter, while Glycerin, increases moisturizing whitening effect.
Compare with prior art, the soft cunning of this hand cream quality, temperature fragrance, fine and smooth homogeneous, deep layer can moisten hand skin,
Tender coarse skin, accelerates wound repair, adjusts skin immune function controlling, strengthens skin and resists environmental stimuli, prevents cold injury, jelly
Skin ulcer, improves cutaneous circulation, enhances metabolism, and so that skin is full of elasticity, softness and have lasting moisturizing power and smooth feeling,
Can effectively help solve the dry and astringent tight uncomfortable sensation of hand, effectively smooth the injury that various problems are brought, with after feel immediately
Obtain comfortable moistening.
Specific embodiment
With reference to embodiment, the present invention will be further described.
The shea butter of the present invention, the Pseudobulbus Bletillae (Rhizoma Bletillae), green tea, Fructus actinidiae chinensiss are commercially available.
Embodiment 1
The preparation of 1.1 bletilla striata extract:
Weigh Pseudobulbus Bletillae (Rhizoma Bletillae) 50g, soak 1h, be heated to 100 DEG C, decoct and extract 3 times, the 1st time plus 12 times amount water, extraction 2h, the 2nd
Secondary plus 10 times amount water, extract 1.5h, the 3rd time plus 8 times amount water, extract 1h, filter every time, merging filtrate, the volume concentration of filtrate
To 6 times of g/ml of Pseudobulbus Bletillae (Rhizoma Bletillae) weight, filter, take filtrate, obtain final product.
The preparation of 1.2 green tea extractive liquors:
Weigh green tea 20g, soak 0.8h, decoct in 100 DEG C of heating and extract 3 times, the 1st time plus 12 times amount water, extract 2h, the
2 times plus 10 times amount water, extract 1.5h, the 3rd time plus 8 times amount water, extract 1h, filter every time, merging filtrate, the volume concentration of filtrate
To 6 times of g/ml of green tea weight, filter, take filtrate, obtain final product.
The preparation of 1.3 Fructus actinidiae chinensiss juicings:
Weigh fresh Fructus actinidiae chinensiss, peeling, stripping and slicing, weigh 30g, put in juice extractor, and add 12 times of distilled water, institute
Obtain Fructus actinidiae chinensis juice double gauze to filter 5 times, filter, take filtrate, obtain final product.
The preparation of 1.4 pyracantha fortuneana juicings:
Weigh fresh pyracantha fortuneana 30g, put in juice extractor, and add 12 times of distilled water, gained pyracantha fortuneana juice is with double
Layer gauze filters 6 times, filters, takes filtrate, obtain final product.
1.5 Flos Rosae Rugosaes are soaked oil and take thing to be prepared by the following method:
Weigh dry Flos Rosae Rugosae 30g, be soaked in 18 times of g/ml Semen Maydis oil, soak 15h, in 40 DEG C of supersound extraction 5h, filter, take
Filtrate, obtains final product.
Herba Saussureae Involueratae described in 1.6 soaks oil and is prepared by the following method:
Weigh dry Herba Saussureae Involueratae 30g, be soaked in 16 times of g/ml Semen Maydis oil, soak 15h, in 50 DEG C of supersound extraction 6h, filter,
Take filtrate, obtain final product.
Myosotis sylvatica described in 1.7 soaks oil and is prepared by the following method:
Weigh Myosotis sylvatica 40g, be soaked in 16 times of g/ml camellia seed oils, soak 20h, in 30 DEG C of supersound extraction 6h, filter,
Take filtrate, obtain final product.
A kind of preparation method of the nutrition moist type hand cream containing natural flowers and fruits plant essence described in 1.8 includes following step
Rapid:
A) weigh sodium alginate 0.5g, be dissolved in 10ml water, be heated to 70 DEG C, heat while stirring, after mix homogeneously, quiet
Put and make it fully swelling, obtain sodium alginate soln；
B) weigh hydroxypropyl methyl cellulose 0.5g, be scattered in 12ml distilled water, be stirred until homogeneous rapidly, standing, from
So swelling 7h, stand-by；
C) shea butter 3.0g, house oil 2.0g, Semen Tritici aestivi germ oil 2.0g are weighed, Flos Rosae Rugosae soaks oily 2g, Herba Saussureae Involueratae soaks oil
2.0g, Myosotis sylvatica soak oily 1.0g, general-purpose self emulsifying mixed emulsifier ac-4022.0g is placed in beaker and protects on water-bath
Hold the melting of temperature 70 C heating in water bath, as oil phase；
D) weigh distilled water 20.0g, 25% triethanolamine solution 2.0g, be placed in 70 DEG C of heating in water bath, obtain aqueous phase；
E) weigh liponic eg-12.0g, 1-2 propylene glycol 3.0g, Sargassum prepared by biological polyoses glue 3.0g, step a)
Gonak prepared by acid sodium solution, step b), is warming up to 90 DEG C, stirs, obtain thickening agent；
F) treat that oil phase melts completely, aqueous phase is poured in oil phase, side edged stirs to same direction, in uniform milky
Paste, obtains final product substrate, and substrate is cooled to room temperature；
G) weigh Mel 0.5g, trehalose 0.5g, nicotiamide 0.4g, vitamin e 0.2g, 20% urea liquid 1.0g, white
Splendid achnatherum extracting solution 0.2g, green tea extractive liquor 0.3g, pyracantha fortuneana juicing 1.0g, Fructus actinidiae chinensiss juicing 1.0g, are uniformly mixed, plus
Enter in the substrate after cooling, obtain cream mastic；
H) by thickening agent made for the cream mastic addition step e) of step g) gained, stirring 10min, mix homogeneously, then
Add 10% citric acid solution 0.2g, adjusting ph is 6.9；
I) it is eventually adding 1% disodium ethylene diamine tetra-acetic acid solution 0.2g, 5% ethyl hydroxybenzoate alcoholic solution 0.5g, second used
Determining alcohol is 75%, and 1% 0.02 part of essence stirs, and obtains final product the nutrition moist type hand cream containing natural flowers and fruits plant essence.
Embodiment 2
Rhizoma Bletillae extraction solution described in 2.1 is to be prepared by the following method:
Weigh Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, soak 0.15h, be heated to 90 DEG C, decoct and extract 3 times, the 1st time plus 11 times amount water, extract
1.5h, the 2nd time plus 8 times amount water, extract 1h, the 3rd time plus 5 times amount water, extract 1h, filter every time, merging filtrate, the volume of filtrate
It is concentrated into 5 times of g/ml of Pseudobulbus Bletillae (Rhizoma Bletillae) weight, filter, take filtrate, obtain final product.
Green tea extractive liquor described in 2.2 is prepared by the following method:
Weigh green tea 20g, soak 0.5h, decoct in 90 DEG C of heating and extract 3 times, the 1st time plus 10 times amount water, extract 1.5h,
2nd time plus 8 times amount water, extract 1h, the 3rd time plus 8 times amount water, extract 1h, filter every time, merging filtrate, the volume concentration of filtrate
To 5 times of g/ml of green tea weight, filter, take filtrate, obtain final product..
Fructus actinidiae chinensiss juicing described in 2.3 is prepared by the following method:
Weigh fresh Fructus actinidiae chinensiss, peeling, stripping and slicing, weigh 50g, put in juice extractor, and add 8 times of distilled water, institute
Obtain Fructus actinidiae chinensis juice double gauze to filter 5 times, take filtrate, stand-by.
Pyracantha fortuneana juicing described in 2.4 is prepared by the following method:
Weigh fresh pyracantha fortuneana 50g, put in juice extractor, and add 10 times of distilled water, gained pyracantha fortuneana juice is with double
Layer gauze filters 5 times, takes filtrate, stand-by.
Flos Rosae Rugosae described in 2.5 is soaked oil and takes thing to be prepared by the following method:
Weigh dry Flos Rosae Rugosae 30g, be soaked in 12 times of g/ml Semen Maydis oil, soak 18h, in 50 DEG C of supersound extraction 6h, filter, take
Filtrate, obtains final product.
Herba Saussureae Involueratae described in 2.6 soaks oil and is prepared by the following method:
Weigh dry Herba Saussureae Involueratae 40g, be soaked in 16 times of g/ml Semen Maydis oil, soak 20h, in 50 DEG C of supersound extraction 6h, filter,
Take filtrate, obtain final product.
The preparation of 2.7 Myosotis sylvaticas immersion oil:
Weigh Myosotis sylvatica 50g, be soaked in 15 times of g/ml camellia seed oils, soak 20h, in 45 DEG C of supersound extraction 5h, filter,
Take filtrate, obtain final product.
A kind of preparation method of the nutrition moist type hand cream containing natural flowers and fruits plant essence described in 2.8, includes following step
Rapid:
A) weigh sodium alginate 0.3g, be dissolved in 8ml water, be heated to 80 DEG C, heat while stirring, after mix homogeneously, quiet
Put and make it fully swelling, obtain sodium alginate soln；
B) weigh hydroxypropyl methyl cellulose 0.3g, be scattered in 9ml water, be stirred until homogeneous rapidly, standing, naturally swelling
7h, stand-by；
C) shea butter 1.0g, house oil 1.0g, Semen Tritici aestivi germ oil 1.0g are weighed, Flos Rosae Rugosae soaks oily 1.0g, Herba Saussureae Involueratae soaks
Oily 2.0g, Myosotis sylvatica soak oily 2.0g, general-purpose self emulsifying mixed emulsifier ac-4022.0g is placed in beaker on water-bath
80 DEG C of heating in water bath meltings of keeping temperature, as oil phase；
D) weigh distilled water 25.0g, 25% triethanolamine solution 2.0g, be placed in 80 DEG C of heating in water bath, obtain aqueous phase；
E) weigh liponic eg-12.0g, 1-2 propylene glycol 3.0g, Sargassum prepared by biological polyoses glue 5.0g, step a)
Gonak prepared by acid sodium solution, step b) is warming up to 80 DEG C, stirs, obtains thickening agent；
F) treat that oil phase melts completely, aqueous phase is poured in oil phase, side edged stirs to same direction, in uniform milky
Paste, obtains final product substrate, and substrate is cooled to room temperature；
G) weigh Mel 0.5g, trehalose 1.0g, nicotiamide 0.2g, vitamin e 0.1g, 20% urea liquid 2.0g, white
Splendid achnatherum extracting solution 0.5g, green tea extractive liquor 0.5g, pyracantha fortuneana juicing 0.5g, Fructus actinidiae chinensiss juicing 0.5g, are uniformly mixed, plus
Enter in the substrate after cooling, obtain cream mastic；
H) by thickening agent made for the cream mastic addition step e) of step g) gained, stirring 15min, mix homogeneously, then
Add 10% citric acid solution 0.2g, adjusting ph is 6.7；
I) it is eventually adding 1% disodium ethylene diamine tetra-acetic acid solution 0.5g, 5% ethyl hydroxybenzoate alcoholic solution 0.5g, wherein second
Determining alcohol is 75%, and 1% 0.01 part of essence stirs, and obtains final product the nutrition moist type hand cream containing natural flowers and fruits plant essence.
Embodiment 3
The physical and chemical index of embodiment 1,2 is as follows:
3.1 character
This product is in pale pink, and denseness is suitable, the soft cunning of quality, fragrant, and fine and smooth homogeneous, stretchability is good, moisturizing, taste
Lubricant nature is good.
3.2ph value checks
Take this product, with ph count measure, record ph value for 6-7 between.
3.3 caloric test
Hand cream is packaged in transparence cosmetic bottle, observes no lamination within one month in 4 DEG C of refrigerator cold-storages.In 55
DEG C calorstat in 24h, the phenomenon such as hand cream is no layered, emulsifying is spoiled.
3.4 centrifugal test
Hand cream is packaged in 3000r/min in tool plug test tube, is centrifuged 20min, no lamination.
3.5 room temperatures place experiment
The made hand cream of embodiment 1,2 is placed in bottle for cosmetics, room temperature standing is investigated 6 months, no lamination is used
After feel unchanged, abnormal smells from the patient is unchanged, no denaturalization phenomenon.
3.6 irritation tests, anaphylaxis experiment
White mice back cuts off hair, smears respectively and does not apply in cutting plucked position, with by the hand cream of embodiment 1,2 preparation
Position is compared, and result does not have zest and anaphylaxiss.
1 gram of Example is applied in volunteer (15-65 year, 80 people) gesture and facial expression, observes after spending 30 minutes, does not all occur sending out
Red, dermexanthesis, foaming phenomena.
The experiment of tryrosinase vigor in 3.7 suppression mouse melanin cells
Take 1g by the hand cream of embodiment 1,2 preparation respectively, respectively plus distilled water 40ml, diluted for use.By b16Melanin
Cell is inoculated in 96 orifice plates, every hole 100 μ l, puts in incubator after culture educates 24h, adds hand cream diluent.Medicine acts on
After 3d, discard the liquid that disappears, rinsed twice with ph 6.8 poly butylene succinate (pbs), every hole adds 90 μ l and contains 1% (volume integral
Number) tritonx-100 pbs.Ultrasonication in ice bath, every hole adds the l- DOPA (l-dopa) of 10 μ l 10mmol/l, incubates for 37 DEG C
Educate 60min, colorimetric at 475nm, blank well returns to zero, and surveys each hole absorbance.
Suppression ratio %=(1- medicine group mean absorbance values ÷ matched group mean absorbance values) × 100%
B16 cell experiment in 3.8 suppression mouse melanin cells
Take 1g by the hand cream of embodiment 1,2 preparation respectively, respectively plus distilled water 40ml, diluted for use.Will be from mice
B16 melanoma cells with 1x105The density of individual/ml is inoculated in culture dish, in 37 DEG C, 5%co2Under conditions of cultivate 2d.Abandon
Clear liquid, adds hand cream diluent, after medicine effect 3d, abandons supernatant, pbs washs, every hole adds 0.5ml trypsin digestion cell
3min, every hole adds 2m1 maintaining liquid and terminates digestion.After piping and druming mixes, every kind of concentration is taken out 0.5ml and is made cell counting.Remaining cell
Suspension is centrifuged 5min with 2500r/min, abandons supernatant, adds naoh solution in precipitation, and heating makes melanin dissolve, and selects
490nm wavelength surveys absorbance on enzyme-linked immunosorbent assay instrument.
B16 cell suppression ratio %=[1- (medicine hole absorbance ÷ medicine hole cell density) ÷ (control wells extinction
Angle value ÷ control wells cell density)] × 100%
3.7-3.8 experimental result is shown in Table 1:
Table 1 experimental result
| Embodiment 1 suppression ratio (%) | Embodiment 2 suppression ratio (%) | |
| Suppression tryrosinase vigor | 59.3 | 59.7 |
| Suppression B16 cell | 65.5 | 67.7 |
Experiment shows, this hand cream has suppression tryrosinase vigor, suppresses melanic synthesis, also illustrates that this hand cream has
Whitening function.
Embodiment 4:
Moist maintenance effect experimental
The moist maintenance effect of embodiment 1,2 is evaluated by experiment on probation.The handguard produced using embodiment 1,2
White and commercially available moist hand cream carries out contrast experiment.Choose 25-45 year the coarse women of hand 120.Their any deciles
Become three groups.The daily morning and evening respectively puts both hands, 1 group of hand cream with preparing by embodiment 1 of embodiment, embodiment on the skin with hand cream twice
2 groups of hand cream with preparing by embodiment 2, matched group smears commercially available moist hand cream, continuously uses two months.Detect by an unaided eye
Improvement on hand is evaluating moist maintenance effect.This results are shown in Table 2:
Table 2 moistens maintenance effect experimental result
| Effectively (people) | Somewhat effectively (people) | Invalid (people) | Total effective rate (%) | |
| Embodiment 1 | 32 | 5 | 3 | 92.45 |
| Embodiment 2 | 34 | 4 | 2 | 95.0 |
| Matched group | 23 | 10 | 7 | 82.5 |
Embodiment 5:
This hand cream resultant effect is investigated
Feel to evaluate the effect of the hand cream that embodiment 1,2 produces following with probation.Using public-opinion poll scoring
Method, choose 80 20-50 year age bracket women as object on probation, be arbitrarily divided into two groups, use embodiment 1,2 to prepare respectively
Hand cream put hand on the skin.Daily using twice, use time two months.Every using effect total score is divided into highest for 5 points: five
Point, represent very well, very satisfied；4 are divided into preferably；3 are divided into and can accept；Less than 3 points is bad it is impossible to accept.It is below each
Item average.Result is shown in 3 tables:
Table 3 resultant effect is investigated
| Using effect | The every average of embodiment 1 | The every average of embodiment 2 |
| Maintenance | 4.8 | 4.9 |
| Alimentary | 4.8 | 4.8 |
| Whitening | 4.5 | 4.6 |
| Moisture retention | 4.8 | 4.7 |
In sum, this made hand cream of the present invention has good maintenance, moist, whitening and softening skin, the work(of moisturizing moisturizing
Effect, has recovery natural elasticity, pale glossy with rear skin.
Claims (10)
1. a kind of nutrition moist type hand cream it is characterised in that in terms of parts by weight its raw material components and content be:
Shea butter 0.5-5.0 part
House oil 0.2-5.0 part
Semen Tritici aestivi germ oil 1.0-5.0 part
Flos Rosae Rugosae soaks oily 1.0-5.0 part
Herba Saussureae Involueratae soaks oily 1.0-5.0 part
Myosotis sylvatica soaks oily 1.0-5.0 part
General-purpose self emulsifying mixed emulsifier ac-402 1.0-5.0 part
25% triethanolamine solution 1.0-5.0 part
Rhizoma Bletillae extraction solution 0.1-3.0 part
Green tea extractive liquor 0.1-3.0 part
Fructus actinidiae chinensiss juicing 0.1-3.0 part
Pyracantha fortuneana juicing 0.1-3.0 part
1,2-PD 1.0-5.0 part
2.0 parts -5.0 parts of biological polyoses glue
20% urea liquid 1.0-5.0 part
Liponic eg-1 1.0-5.0 part
Trehalose 0.5-5.0 part
Nicotiamide 0.01-1.0 part
Mel 0.1-2.0 part
Vitamin e 0.1-1.0 part
Sodium alginate 0.01-0.5 part
Hydroxypropyl methyl cellulose 0.01-0.5 part
1% disodium ethylene diamine tetra-acetic acid solution 0.01-5.0 part
10% citric acid solution 0.1-5.0 part
5% ethyl hydroxybenzoate alcoholic solution 0.01-5.0 part
Distilled water 10.0-72.0 part
1% essence 0.01-0.05 part.
2. nutrition moist type hand cream according to claim 1 it is characterised in that described Rhizoma Bletillae extraction solution be by with
Lower section method preparation:
Weigh the Pseudobulbus Bletillae (Rhizoma Bletillae) appropriate, soak 0.15-1h, be heated to 90-100 DEG C, decoct and extract 3 times, the 1st time plus 6-12 times amount water, carry
Take 0.5-2h, the 2nd time plus 4-10 times amount water, extract 0.5-1.5h, the 3rd time plus 3-8 times amount water, extract 0.5-1.5h, filter every time
Cross, merging filtrate, the volume concentration of filtrate, to 3-6 times of g/ml of Pseudobulbus Bletillae (Rhizoma Bletillae) weight, filters, takes filtrate, obtain final product.
3. nutrition moist type hand cream according to claim 1 is it is characterised in that described green tea extractive liquor is by following
Prepared by method:
Weigh green tea appropriate, soak 0.15-0.8h, decoct in 90-100 DEG C of heating and extract 3 times, the 1st time plus 6-12 times amount water, carry
Take 0.5-2h, the 2nd time plus 4-10 times amount water, extract 0.5-1.5h, the 3rd time plus 3-8 times amount water, extract 0.5-1.5h, filter every time
Cross, merging filtrate, the volume concentration of filtrate, to 3-6 times of g/ml of green tea weight, filters, takes filtrate, obtain final product.
4. nutrition moist type hand cream according to claim 1 it is characterised in that described Fructus actinidiae chinensiss juicing pass through with
Lower section method preparation:
Weigh fresh Fructus actinidiae chinensiss, peeling, stripping and slicing, weigh a certain amount of, put in juice extractor, and add the distillation of 8-12 times of g/ml
Water, gained Fructus actinidiae chinensis juice is filtered 3-6 time with double gauze, filters, takes filtrate, obtain final product.
5. nutrition moist type hand cream according to claim 1 it is characterised in that described pyracantha fortuneana juicing pass through with
Lower section method preparation:
Weigh fresh pyracantha fortuneana a certain amount of, put in juice extractor, and add the distilled water of 8-12 times of g/ml, gained pyracantha fortuneana juice
Filtered 3-6 time with double gauze, filter, take filtrate, obtain final product.
6. nutrition moist type hand cream according to claim 1 is it is characterised in that described Flos Rosae Rugosae soaks oil by following
Prepared by method:
Weigh dry Flos Rosae Rugosae appropriate, be soaked in 10-18 times of g/ml Semen Maydis oil, soak 12-24h, in 30-60 DEG C of supersound extraction 5-
6h, filters, takes filtrate, obtain final product.
7. nutrition moist type hand cream according to claim 1 it is characterised in that described Herba Saussureae Involueratae soak oil by with
Lower section method preparation:
Weigh dry Herba Saussureae Involueratae appropriate, be soaked in 10-18g/ml times of Semen Maydis oil, soak 12-24h, in 30-60 DEG C of supersound extraction 5-
6h, filters, takes filtrate, obtain final product.
8. nutrition moist type hand cream according to claim 1 it is characterised in that described Myosotis sylvatica soak oil by with
Lower section method preparation:
Weigh Myosotis sylvatica appropriate, be soaked in 10-18g/ml times of camellia seed oil, soak 12-24h, in 30-60 DEG C of supersound extraction 5-
6h, filters, takes filtrate, obtain final product.
9. nutrition moist type hand cream according to claim 1 is it is characterised in that described essence is rose essence, water
One of honey peach essence, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence, osmanthus flower fragrance.
10. a kind of preparation method of the nutrition moist type hand cream described in claim 1 is it is characterised in that methods described includes
Following steps:
A) weigh sodium alginate 0.01-0.5 part, be dissolved in 1-10 part distilled water, be heated to 60-80 DEG C, heat while stirring, mix
After closing uniformly, standing makes it fully swelling, obtains sodium alginate soln；
B) weigh hydroxypropyl methyl cellulose 0.01-0.5 part, be scattered in 5-12 part distilled water, be stirred until homogeneous rapidly, quiet
Put, naturally swelling 5-7h, stand-by；
C) shea butter 0.5-5.0 part, house oil 0.2-5.0 part, Semen Tritici aestivi germ oil 1.0-5.0 part, the oily 1.0- of Flos Rosae Rugosae immersion are weighed
5.0 parts, Herba Saussureae Involueratae soaks oily 1.0-5.0 part, Myosotis sylvatica soaks oily 1.0-5.0 part, general-purpose self emulsifying mixed emulsifier ac-
402 1.0-5.0 parts are placed in keeping temperature 60-90 DEG C heating in water bath melting on water-bath in beaker, as oil phase；
D) weigh distilled water 4.0-50.0 part, 25% triethanolamine solution 1.0-5.0 part, be placed in 60-90 DEG C of heating in water bath, obtain
Aqueous phase；
E) liponic eg-1 1.0-5.0 part, 1-2 propylene glycol 1.0-5.0 part, 2.0 parts -5.0 parts of biological polyoses glue, step are weighed
Rapid sodium alginate soln a) prepared, the Gonak of step b) preparation, are heated to 80-90 DEG C, stir
Mix uniformly, obtain thickening agent；
F) treat that oil phase melts completely, aqueous phase is poured in oil phase, side edged stirs to same direction, in uniformly milky white color
Shape, obtains final product substrate, and substrate is cooled to room temperature；
G) weigh Mel 0.1-2.0 part, trehalose 0.5-5.0 part, nicotiamide 0.01-1.0 part, vitamin e 0.1-1.0 part,
20% urea liquid 1.0-5.0 part, Rhizoma Bletillae extraction solution 0.1-3.0 part, green tea extractive liquor 0.1-3.0 part, pyracantha fortuneana juicing
0.1-3.0 part, Fructus actinidiae chinensiss juicing 0.1-3.0 part, are uniformly mixed, and add in the substrate after cooling, obtain cream mastic；
H) to the thickening agent that the cream mastic addition step e) of step g) gained is made, stirring 10-15min, mix homogeneously, then plus
Enter 10% citric acid solution 0.1-5.0 part, adjust ph between 6-7；
I) it is eventually adding 1% disodium ethylene diamine tetra-acetic acid solution 0.01-5.0 part, 5% ethyl hydroxybenzoate alcoholic solution 0.01-5.0
Part, wherein concentration of alcohol is 75%, and 1% essence 0.01-0.05 part stirs, obtains final product the nutrition containing natural flowers and fruits plant essence
Moist type hand cream.
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| CN105997964A (en) * | 2016-04-18 | 2016-10-12 | 中华全国供销合作总社南京野生植物综合利用研究院 | Efficacy type sterilization and disinfection liquid containing natural citral-bletilla striata polysaccharide polymer and preparation method thereof |
| CN108379213A (en) * | 2016-12-14 | 2018-08-10 | 天津强微特生物科技有限公司 | A kind of moisture-keeping crease-shedding hand lotion |
| CN107569432B (en) * | 2017-08-29 | 2020-05-19 | 皖南医学院 | Herbal hand cream capable of nourishing, whitening, relieving and replenishing water and preparation method thereof |
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| CN107823038A (en) * | 2017-10-28 | 2018-03-23 | 安徽孔氏奇医药科技有限公司 | A kind of replenishing water and preserving moisture hand lotion and preparation method thereof |
| CN107714613A (en) * | 2017-11-15 | 2018-02-23 | 陈荷芬 | One kind is without sticky sense moist type hand cream |
| CN108309848B (en) * | 2018-03-27 | 2020-08-04 | 上海清轩生物科技有限公司 | Preparation method of chlorella extract and anti-aging composition thereof |
| CN108542851A (en) * | 2018-06-28 | 2018-09-18 | 芜湖扬展新材料科技服务有限公司 | A kind of Chinese medicine moisturizing anti-chapping hand cream and preparation method thereof |
| CN109820842B (en) * | 2018-11-20 | 2022-01-11 | 中国科学院昆明植物研究所 | Application of yam extract III in preparation of medicines and cosmetics |
| CN109820860A (en) * | 2019-04-19 | 2019-05-31 | 江苏远恒药业有限公司 | A kind of Compound Miconazole nitrate Cream and its preparation process |
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| CN102370604A (en) * | 2010-08-22 | 2012-03-14 | 郝允敏 | Hand cream and preparation method thereof |
| CN102908301A (en) * | 2012-11-15 | 2013-02-06 | 李欣欣 | Anti-chapping hand cream and preparation method thereof |
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Effective date of registration: 20190515 Address after: Room 4310, No. 1, 285 Lane, Tiangong Road, Jinshan Industrial Zone, Shanghai, 201506 Patentee after: SHANGHAI MEIFUTE BIOTECHNOLOGY Co.,Ltd. Address before: 241002 No. 22 Wenchang West Road, Yijiang Higher Education Park, Wuhu, Anhui Patentee before: Wannan Medical College |
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Denomination of invention: A nutritious and moisturizing hand cream and its preparation method Effective date of registration: 20230913 Granted publication date: 20170201 Pledgee: Jinshan Sub branch of Bank of Shanghai Co.,Ltd. Pledgor: SHANGHAI MEIFUTE BIOTECHNOLOGY Co.,Ltd. Registration number: Y2023980056262 |