CN104173261B - Soothing, anti-allergy and skin-regenerating emulsion and preparation method thereof - Google Patents
Soothing, anti-allergy and skin-regenerating emulsion and preparation method thereof Download PDFInfo
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- CN104173261B CN104173261B CN201410432411.8A CN201410432411A CN104173261B CN 104173261 B CN104173261 B CN 104173261B CN 201410432411 A CN201410432411 A CN 201410432411A CN 104173261 B CN104173261 B CN 104173261B
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a soothing, anti-allergy and skin-regenerating emulsion and a preparation method thereof. The emulsion contains the following substances: sweet almond oil, macadamia nut oil, wheat-germ oil, evening primrose oil, a universal simple emulsifier, water-soluble jojoba oil, water-soluble Ve, biological guar gum, a cell activating agent, an amino acid moisturizing agent, trehalose, stevia leaf extract, hibiscus leaf extract, gentian extract, rhizoma ligustici wallichii root extract, honey, distilled water, glycerin, 1,2-propylene glycol, ethylparaben, and essence. Compared with existing emulsions, the emulsion prepared according to the invention is gentle and non-irritant, and has obvious soothing and regenerating effects; effective ingredients in the natural vegetable oils moisten the skin most gently, ingredients with the functions of moisturizing and activating cells enable the skin to keep moisturized, and active substances in natural Chinese herbal medicine plants can calm and relax the skin, promote the blood circulation, keep the skin moisturized, and endow cell vitality, so that the skin shines from inside to outside.
Description
Technical field
The present invention relates to a kind of emulsion and preparation method thereof, moisten particularly to a kind of reparation that sensitivity skin is releived
Effect type repair latex of effect and preparation method thereof.
Background technology
Environmental pollution now is serious, and dust present in air, granule, harmful substance cause a certain degree of wound to skin
Evil, in life, pressure is big, stay up late, sitting, long-time allow the skin of people seeking beauty in the face of the many factors such as computer, endocrine disturbance
Enjoy challenge.The pale resilient skin of smooth exquisiteness is that every people seeking beauty dreams of, even more sensitivity skin crowd
Yearned for, but the skin of sensitivity enjoyed restriction on the road of skin protection by be allowed people seeking beauty.
Sensitive skin is a kind of special state of skin, and skin fragility is vulnerable, is easily occurred by after environmental stimuli
Red blood streak, the symptom such as edema, telangiectasis, skin easily has prurituss, twinge, scorching hot, the sensation such as tight feeling.Sensitive skin
Feature mainly show as：Seasonal conversion, temperature, humidity, wind, daylight, irradiated skin, easily general red, have prurituss, twinge and
Burning sensation, or even little erythema occurs.Can be caused using skin-protection product (including face cleaning, moisturizing, astringent, color make-up, sunscreen productses etc.)
Flushing, itch or twinge, scorching hot, prurituss, desquamation etc..Often feel after washing one's face that skin is micro- red, tingle.Middle intensity kinesis, feelings
Thread fluctuation cutaneous vasodilation, hyperemia, rubescent.Unsuitable diet such as spicy food, ethanol and overheated diet all can cause
Cutaneous vasodilation, hyperemia, rubescent.The epidermal area of sensitivity skin is relatively thin, lacks the defence capability to ultraviolet, easily always
Change, the shallow horny layer of sensitivity skin usually can not maintain enough moisture, either in the cold air room in summer, or
In the weather that winter is dried, there is the people of this skin quality, can more observantly feel skin hydropenia, drying than common people, because
And it is extremely important to strengthen moisturizing in operational maintenance.
Therefore, the people of this kind of skin, in application maintenance product, answers the product that concentration is moderate or low, just more appropriate
When.The stimulation to sensitive skin also will be reduced as far as possible.Skin, when dry, desquamation or rubescent situation, illustrates skin
Health status flash the redlight.Skin to be allowed restores as early as possible, and the best way is exactly to reduce stimulation, does not excessively by the wind blow, Exposure to Sunlight,
Do not eat irritable food, then reuse hypoallergenic series of products, after harm reduction, skin can voluntarily be got well.
Modern most of cosmetics, it is emphasised that high efficiency, therefore it is required that its active component allows for passing through
Skin, is applied to deep skin and could produce high effect, sensitive skin can not too nourish in fact.
Content of the invention
For solving above-mentioned technical problem, the reparation skin emulsion the invention provides a kind of antiallergic is releived.
Repair the preparation method of skin emulsion present invention also offers planting antiallergic and releiving.
A kind of antiallergic that the present invention provides is releived and is repaired skin emulsion, contains following material in 83.0g emulsion：
Described Flos Chrysanthemi leaf extract is prepared in the following manner：
Weigh Folium Chrysanthemi appropriate, after pulverizing, soak 30-50min, heat in 90-100 DEG C and decoct extraction 3 times, the 1st time plus 5-
12 times amount water, extract 0.5-2.5h, the 2nd time plus 4-10 times amount water, extract 0.5-2.0h, the 3rd time plus 3-8 times amount water, extract
0.5-1.5h, filters, merging filtrate every time, and the volume concentration of filtrate, to 2-6 times of g/ml of Folium Chrysanthemi weight, filters and obtains final product Flos Chrysanthemi
Leaf extract.
Described Hibiscus syriacus L. leaf extract is prepared by the following method：
Weigh Folium Hibisci appropriate, soak 30-50min, decoct in 90-100 DEG C of heating and extract 3 times, the 1st time plus 6-12 times amount
Water, extracts 0.5-2h, the 2nd time plus 4-10 times amount water, extracts 0.5-1.5h, the 3rd time plus 3-8 times amount water, extracts 0.5-1.5h, often
Secondary filtration, merging filtrate, the volume concentration of filtrate, to 2-6 times of g/ml of Folium Hibisci weight, filters and obtains final product Hibiscus syriacus L. leaf extract.
Described Radix Gentianae extracting solution is prepared in the following manner：
Weigh Radix Gentianae appropriate, for the first time plus 8-15 times of 70%-80% ethanol, reflux, extract, 0.5-2h, sucking filtration, second
Plus 8-15 times of 70%-80% ethanol, reflux, extract, 0.5-2h, sucking filtration, third time plus 6-10 times of 70%-80% ethanol, backflow
0.5-1.5h, sucking filtration, three times filtrate merges, and the volume concentration of filtrate is 3-8 times of g/ml of medical material amount, obtains final product Radix Gentianae and extracts
Liquid.
Described Rhizoma Chuanxiong root extracting solution is prepared in the following manner：
After weighing the appropriate pulverizing of Rhizoma Chuanxiong root, soak 0.15-0.5h with ethanol, returned with the ethanol of 8-15 times amount 50%-90%
Stream extracts 0.5-2.5h, filters, then the alcohol reflux 0.5-2.5h with 8-15 times amount 50%-90%, filters, then uses 5-10
The alcohol reflux 0.5-2.5h of times amount 50%-90%, filters, and three filtrates is merged, the decompression volume of filtrate is concentrated to
4-7 times of g/ml of medical material amount, obtains final product Rhizoma Chuanxiong root extracting solution.
Described essence be rose essence, peach flavor, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence,
Osmanthus flower fragrance.
The present invention provide a kind of antiallergic releive repair skin emulsion preparation method it is characterised in that：
A) macadimia nut oil 0.8-1.3g, Semen pruni armeniacae oil 0.7-1.2g, Semen Tritici aestivi germ oil 0.6-1.0g, Radix Oenotherae erythrosepalae oil are weighed
0.3-0.8g, simply emulsifying agent 0.5-1.0g all can be added in beaker, be put into heating in 70-95 DEG C of thermostat water bath, make
Stand-by for solution 1；
B) water solublity Jojoba oil 1.0-1.3g, water solublity Ve 0.5-0.7g, cell vitalizing agent 1.0-1.2g, ammonia are weighed
Base acid wetting agent 0.5-0.6g, biological polyoses glue 1.0-1.2g, trehalose 0.5-0.8g, Mel 1.0-1.8g are added to beaker
In, it is eventually adding distilled water 65.0-75.0g and beaker is put in 70-95 DEG C of water-bath, stand-by as solution 2；
C) treat that solution 1, solution 2 temperature are identical, solution 2 is slowly added in solution 1 with Glass rod drain, side edged stirs
Mix, until forming homogeneous white milky liquid 3；
D) ethyl hydroxybenzoate 0.01-0.05g is dissolved in glycerol 1-4ml, 1,2-PD 1-4ml, forms liquid 4；
E) Flos Chrysanthemi leaf extract 0.1-0.3g, Hibiscus syriacus L. leaf extract 0.2-0.5g, Radix Gentianae extracting solution are added toward in liquid 3
0.4-1.0g, Rhizoma Chuanxiong root extracting solution 0.4-1.0g, essence 0.01-0.05ml and liquid 4, with Glass rod stirring until emulsion is equal
Even, obtain final product antiallergic releive reparation skin emulsion.
Various composition in the present invention is as follows：
Semen pruni armeniacae oil all has obvious moisturizing effect for dryness, sensitivity, tender and lovely, aging skin, easily absorbs, and protects
Hold the moisture of skin, contribute to allowing skin become glossy.It can soften and releive skin it is also possible to promote Skin Cell
Healthy growth.Some sensitive skin, acne, prurituss, inflamed skin are also to use.It has the function of filters ultra violet line,
So there being anti-sunlight function.
In the numerous compositions of macadimia nut oil, carotene and chlorophyll give the golden yellow uniqueness revealing the green of macadimia nut oil
Color and luster, and chlorophyll plays metabolism, promotes cell growth, accelerating wound healing, additionally aids nutrition and beautifying skin,
Reduce the generation of wrinkle.Macadimia nut oil or a kind of natural drug of fabulous treatment dermatosis.According to department of dermatologry external
Medicine Therapeutic Principle, 3 being made with macadimia nut oil kind dosage form is evident in efficacy to 5 class 15 kinds of exudative dermatitiss, ulcer.Due to Australia
Macadamia nut oil contains polyphenol and lipopolysaccharide components, so macadimia nut oil also has the function of radioprotective, commonly used computer person more regards
It is the good merchantable brand of health-care and skin-care.
Semen Tritici aestivi germ oil can effectively facilitate the metabolism of skin, strengthens the moisture-keeping functions of skin, and conditioning women's is interior
Secretion, thus improving skin from inside to outside, reduces black speck and pigmented spots, strengthens skin anti-aging and crease-resistant moisture-keeping functions, order
Women skin becomes soft and moist and high resilience, also by conditioning endocrine, can eliminate deposition in cell for the lipofuscin, light speckle,
Keep skin water and oil balance.The vitamin e of high-load, can strengthen the connective tissue of skin, promote blood circulation, keep skin bullet
Property, it is possible to reduce the scar that injured or operation causes is additionally it is possible to reduce the vestige that comedo stays on the face.It is applied to various skin quality
Especially chronic eczema, dry eczema, wrinkle, cicatrix, striae gravidarum, black speck skin, is best suited for old and feeble and ripe skin.
Radix Oenotherae erythrosepalae oil contains satisfied fatty acid and unsaturated fatty acid, the wherein high-carbon fat such as Oleic acid, linoleic acid, gamma-Linolenic acid
Fat acid content is very high, has resilient flexible sense to skin, and its tactile and ductility very well, and are easily absorbed by skin heart, can promote
Enter blood circulation, prevent epidermis cell keratinization, make skin keep lubrication, delay skin aging.Radix Oenotherae erythrosepalae oil contains satisfied fatty acid
There is provided sufficient toughness with unsaturated fatty acid for skin texture and prevent moisture of skin from losing, skin can be recovered and normally shield
Barrier function, is outstanding moisturizing agent in cosmetics and wetting agent.Radix Oenotherae erythrosepalae oil is harmless, non-stimulated, and to burn, de-
Send out, acne, chloasma, seborrheic dermatitis, wound have preferable medical assistance effect.
Water solublity Jojoba oil is suitable for all skin quality, particularly dry, coarse, dark and gloomy, oiliness, comedo skin quality.It
Permeability and heat-resisting quantity are splendid, and molecules align is very similar with the sebum of people, have very significant beauty functions to skin.Can
For unimpeded pore, adjust the fat secretion of oiliness or miscibility skin, improve skin inflammation and sensitivity, eczema, chronic eczema, pimples
Deng.It moisten and moistening effect is also fine, moisture of skin can be increased, pre- anti-wrinkle and aging.It is a kind of water-soluble emollient,
Skin care and never greasy, very thin protecting film is formed on skin, so that epidermis cell is arranged tightr, effectively prevent moisture
Excessive volatilization.
Water solublity Ve has softening skin horny layer, accelerates epidermis cell metabolism, desalinates tegumentary chromatophore and subtracts
Obvious effect of few lipid peroxy reaction, is a kind of common crease-resistant, nutrition, skin moistening, the beauty treatment additive of desalination mottle, wide
General it is applied to cosmetics, skin care item, is particularly suited for water based transparent product.Vitamin E can neutralize oxygen-derived free radicals, protects cell membrane
From Free radicals injury, suppress the lipid peroxide such as speckle to generate, effectively resist old and feeble.Vitamin E suppresses tryrosinase
Activity, thus reduce melanin generate, eliminating chloasma.Vitamin E can suppress lipid peroxy to react, and keeps contacting between tissue,
Make skin smooth, flexible.Vitamin E can help repair and consolidate the natural protective barrier of skin, pin moisture in skin, carry
Nourish for deep layer from inside to outside.Vitamin E energy anti-lipid peroxidation thing gathers in blood vessel wall, prevents intravascular coagulation,
Improve blood circulation, make body youth vibrant.
Mel has stronger moisturizing, and its nutritional labeling is natural nutrient substance, and its monosaccharide, vitamin, enzyme etc. are raw
Active substances are conducive to by the absorption of Skin Cell, can not only effectively improve the nutritional statuses of skin surface, make skin thin
Greasy, keep nature ruddy, and be conducive to the aging of delaying skin cell, thus play delaying or mitigate the effect such as wrinkle.
Biological polyoses glue is a kind of 1% linearly poly polysaccharide viscosity solution, has moisture-keeping efficacy, is " active excipient ".
Silk sliding sensation can be brought during 7% consumption.It can adjust the emotion of user, gives happy sensory experience and happy
Sensation.
Cell vitalizing agent MG-60 is that mycoside (natural moisture preserving composition) adds water amylolysis thing mixed solution, main work(
It can be cell-activating effect；Avoid the protective effect that cell is dried；Because ultraviolet irradiating cell will sustain damage, by adding
Plus MG-60, the extent of damage is mitigated；MG-60 inhibits the generation of one of inflammatory cytokines TNF-a, has antiinflammatory and makees
With.
Amino acid humectant NMF-50 is natural moisture preserving agent, and tool high biological compatibility, for energy in personal care product
Improve rapidly the water holding capacity that skin is sent out, activated cell vigor, make that skin is moist, smooth, prevent from being dried and shade.
Trehalose, also known as Yeast sugar, has the specific function preserving biologos.It can protect cell membrane and egg effectively
White matter structure, thus the structure of cell, texture, color and luster can be kept.
Folium Hibisci is cool in nature, nontoxic, has the work(of heat clearing away, dampness removing, removing heat from blood, can control scabies, the disease such as furuncle furuncle and phyma.Folium Hibisci is cleaned
Afterwards, soaked with clear water, rub out contained glue juice, prevent skin aging, adjust the fat secretion of skin, skin can be made to releive, make
Skin is smooth, and non-greasy is salubrious, high resilience.
Radix Gentianae is beauty treatment medical material, has functions that to releive, calm and Glycerin, either takes orally or external, is all
Precious beauty treatment medical material.Radix Gentianae extract after fine extraction is used in skin care item, so that skin resistance is naturally strengthened,
Have effect of whitening and moisturizing concurrently simultaneously.
Folium Chrysanthemi can allaying tiredness, foster essence refreshes oneself, and adjusts blood glucose, fat-reducing and beauty, pure and fresh abnormal smells from the patient makes people's mood pleasant, happy
The refrigerant love of inclining that lets people of people.
Rhizoma Chuanxiong root has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.To calm skin, blood circulation promoting has obvious effect.
Glycerol Glycerin, can form one layer of glycerol thin film on skin, and isolation air invades, and make moisture in skin not
Easily evaporate, and the moisture of absorbable in the air carrys out skin care, thus being effectively prevented chapped skin.
The viscosity of 1,2-PD and good hygroscopicity, are widely used as hygroscopic agent, antifreeze, lubricant in cosmetics industry
And solvent.Because propylene glycol and all kinds of spice have preferable intersolubility, thus also serve as solvent and softening agent of cosmetics etc..
Ethyl hydroxybenzoate is the sterilization antiseptic of food, medicine, cosmetics etc..
Emulsion made by the present invention is creamy white, and viscosity is suitable, and fine and smooth uniform, stretchability is good, cool and comfortable, surely
Qualitative good, there is light fragrance after smearing, skin comfort loosens.
Compare with prior art, the amino acid humectant that contains in product of the present invention, cell vitalizing agent, trehalose etc. have
Good moisturizing effect energy, ensure that the demand of personage's moisturizing in any season of sensitive skin；And do not add and swash
Element, ethanol etc., gently do not stimulate, have preferable moisturizing, water lock effect, the natural plant oil of interpolation moistens sensitive impaired flesh
Skin, the Chinese medicinal herb essence such as the Folium Chrysanthemi of interpolation, Folium Hibisci, Radix Gentianae releives the appropriate oil-water ratio of skin to skin optimum
Care, product of the present invention has releives, repair and moisturizing, recover skin system of defense function, skin sensitivity can be reduced
Degree, drives away low and deep, reappears skin health honorable.
Specific embodiment
With reference to embodiment, the present invention will be further described.
The Semen pruni armeniacae oil of the present invention, macadimia nut oil, Semen Tritici aestivi germ oil, Radix Oenotherae erythrosepalae oil, all-round simple emulsifying agent, water solublity
Ve, biological polyoses glue, cell vitalizing agent, amino acid humectant, trehalose, water solublity Jojoba oil, glycerol, 1,2 propylene glycol, Buddhist nun
The golden ethyl ester of pool, essence are commercially available.
Embodiment 1
The preparation of 1.1 Flos Chrysanthemi leaf extracts
Weigh Folium Chrysanthemi appropriate, after pulverizing, soak 45min, decoct in 100 DEG C of heating and extract 3 times, the 1st time plus 12 times amount
Water, extracts 1.5h, the 2nd time plus 8 times amount water, extracts 1.0h, the 3rd time plus 6 times amount water, extracts 0.5h, filters every time, merges filter
Liquid, 6 times of g/ml of the volume concentration of filtrate to Folium Chrysanthemi weight, filtration obtains final product.
The preparation of 1.2 Hibiscus syriacus L. leaf extracts
Weigh Folium Hibisci appropriate, soak 50min, decoct in 100 DEG C of heating and extract 3 times, the 1st time plus 10 times amount water, extract
1h, the 2nd time plus 8 times amount water, extract 1h, the 3rd time plus 6 times amount water, extract 1.0h, filter every time, merging filtrate, the volume of filtrate
It is concentrated into 6 times of g/ml of Folium Hibisci weight, filtration obtains final product.
The preparation of 1.3 Radix Gentianae extracting solution
Weigh Radix Gentianae 8g, add 13 times of 75% ethanol, reflux, extract, 1.5h, sucking filtration for the first time, add 10 times 75% second
Ethanol, reflux, extract, 1h, sucking filtration, third time plus 8 times of 75% ethanol, flow back 1h, sucking filtration, and three times filtrate merges, and concentrates as medical material
5 times of g/ml of amount, filtration obtains final product.
The preparation of 1.4 Rhizoma Chuanxiong root extracting solution
After weighing that Rhizoma Chuanxiong root is appropriate and pulverizing, soak 0.5h with ethanol, with the alcohol reflux 1.5h of 10 times amount 80%, then
With the alcohol reflux 1h of 8 times amount 80%, by filtrate reduced in volume, then the alcohol reflux 1h with 6 times amount 95%, mistake
Filter, by 6 times of g/ml of filtrate reduced in volume to medical material amount, filtration obtains final product.
The preparation of 1.5 emulsions
A) accurately weigh macadimia nut oil 1.0g, Semen pruni armeniacae oil 1.0g, Semen Tritici aestivi germ oil 1.0g, Radix Oenotherae erythrosepalae oil 0.7g, complete
Simple emulsifying agent 0.8g can be added in beaker, be put into heating in 85 DEG C of thermostat water bath, stand-by as solution 1.
B) water solublity Jojoba oil 1.0g, water solublity Ve 0.7g, cell vitalizing agent MG-60 1.0g, amino are accurately weighed
Sour wetting agent NMF-50 0.6g, biological polyoses glue Fucogel 1.0g, trehalose 0.7g, Mel 1.6g are added in beaker,
Distilled water 75.0g is added to put in 85 DEG C of water-bath by beaker afterwards, stand-by as solution 2.
C) treat that solution 1, solution 2 temperature are identical, solution 2 is slowly added in solution 1 with Glass rod drain, side edged stirs
Mix, until forming homogeneous white milky liquid 3；
D) ethyl hydroxybenzoate 0.04g is dissolved in glycerol 4ml, 1,2-PD 4ml, forms liquid 4；
E) Flos Chrysanthemi leaf extract 0.2g, Hibiscus syriacus L. leaf extract 0.3g, Radix Gentianae extracting solution 0.6g, river are added toward in liquid 3
Rhizome of chuanxiong root extracting solution 0.6g, essence 0.02ml and liquid 4, with Glass rod stirring until emulsion uniformly, obtains final product antiallergic and releives reparation flesh
Skin emulsion.
Example 2
The preparation of 2.1 Flos Chrysanthemi leaf extracts
Weigh Folium Chrysanthemi appropriate, after pulverizing, soak 45min, decoct in 100 DEG C of heating and extract 3 times, the 1st time plus 10 times amount
Water, extracts 1.5h, the 2nd time plus 9 times amount water, extracts 1.0h, the 3rd time plus 8 times amount water, extracts 1h, filters every time, merging filtrate,
The volume concentration of filtrate, to 6 times of g/ml of Folium Chrysanthemi weight, filters and obtains final product Flos Chrysanthemi leaf extract.
The preparation of 2.2 Hibiscus syriacus L. leaf extracts
Weigh Folium Hibisci appropriate, soak 50min, decoct in 100 DEG C of heating and extract 3 times, the 1st time plus 12 times amount water, extract
1h, the 2nd time plus 10 times amount water, extract 1h, the 3rd time plus 8 times amount water, extract 0.5h, filter every time, merging filtrate, the body of filtrate
Long-pending 6 times of g/ml being concentrated into Folium Hibisci weight, filtration obtains final product.
The preparation of 2.3 Radix Gentianae extracting solution
Weigh Radix Gentianae 8g, add 13 times of 75% ethanol, reflux, extract, 1.5h, sucking filtration for the first time, add 10 times 75% second
Ethanol, reflux, extract, 1h, sucking filtration, third time plus 8 times of 75% ethanol, flow back 1h, sucking filtration, and three times filtrate merges, the volume of filtrate
Concentrate 5 times of g/ml for medical material amount, filtration obtains final product.
The preparation of 2.4 Rhizoma Chuanxiong root extracting solution
After weighing that Rhizoma Chuanxiong root is appropriate and pulverizing, soak 0.5h with ethanol, with the alcohol reflux 1h of 10 times amount 80%, then use
The alcohol reflux 1h of 8 times amount 80%, by filtrate reduced in volume, then the alcohol reflux 1h with 8 times amount 95%, filter,
By filtrate reduced in volume to medical material amount 6 times.
The preparation of 2.3 emulsions
A) accurately weigh macadimia nut oil 1.0g, Semen pruni armeniacae oil 1.0g, Semen Tritici aestivi germ oil 1.0g, Radix Oenotherae erythrosepalae oil 0.7g, complete
Simple emulsifying agent 0.8g can be added in beaker, be put into heating in 85 DEG C of thermostat water bath, stand-by as solution 1.
B) water solublity Jojoba oil 1.0g, water solublity Ve 0.7g, cell vitalizing agent MG-60 1.0g, amino are accurately weighed
Sour wetting agent NMF-50 0.6g, biological polyoses glue Fucogel 1.2g, trehalose 0.7g, Mel 1.6g are added in beaker,
Add distilled water 75.0g afterwards, beaker is put in 85 DEG C of water-bath, stand-by as solution 2.
C) treat that solution 1, solution 2 temperature are identical, solution 2 is slowly added in solution 1 with Glass rod drain, side edged stirs
Mix, until forming homogeneous white milky liquid 3；
D) ethyl hydroxybenzoate 0.04g is dissolved in glycerol 4ml, 1,2-PD 4ml, forms liquid 4；
E) Flos Chrysanthemi leaf extract 0.3g, Hibiscus syriacus L. leaf extract 0.4g, Radix Gentianae extracting solution 1.0g, river are added toward in liquid 3
Rhizome of chuanxiong root extracting solution 1.0g, essence 0.04ml and liquid 4, with Glass rod stirring until emulsion uniformly, obtains final product antiallergic and releives reparation flesh
Skin emulsion.
Embodiment 3
The physical and chemical index of embodiment 1,2 is as follows：
3.1 character
Emulsion made by the present invention is creamy white, and viscosity is suitable, and fine and smooth uniform, stretchability is good, cool and comfortable, surely
Qualitative good.
3.2pH value checks
Dip a small amount of emulsion with the pH reagent paper of moistening, pH is 6-7, is directly suitable for skin.
3.3 caloric test
Emulsion is packaged in transparence cosmetic bottle, observes no lamination within one week about in 4 DEG C of refrigerator cold-storages.In 55
DEG C calorstat in 24h, emulsion is no layered, the phenomenon such as spoiled.
3.4 centrifugal test
Emulsion is packaged in 3000r/min in tool plug test tube, is centrifuged 20min, no lamination.
3.5 irritation tests, anaphylaxis experiment
Shave off the hair about 2.5cm of rabbit back2, rest 24h, after the stimulation recovery from illness that shaving produces, take emulsion 1.0g, uniformly
Coat shaving position.Observe after 24h and have or not rubescent, rash, blister etc., result is no rubescent, play rash, blister.
Take emulsion finished product 1g to be applied on volunteer (20-60 year, 40 people) gesture and facial expression and face, observe after spending 30 minutes, all do not have
Rubescent, dermexanthesis, foaming phenomena occur.
3.6 room temperatures place experiment
The made emulsion of embodiment 1,2 is placed in bottle for cosmetics, room temperature standing is investigated 4 months, no lamination, after using
Feel unchanged, abnormal smells from the patient is unchanged.
3.7 releive repairing effect
Take emulsion finished product 1.5g to be applied to volunteer (20-60 year, 40 people) gesture and facial expression and face, observe after spending 30 minutes, all do not have
Rubescent, dermexanthesis, foaming phenomena occur.There is moist the showing of change with the hand skin of face of the volunteer of rear first quarter moon 87.39%
As the red blood streak of 71.43% face has the more apparent phenomenon shoaling.Illustrate that this emulsion is releived to most of anaphylaxis skin taste
Profit repairs effect of skin.
Embodiment 4：
This emulsion resultant effect is investigated
Feel to evaluate the effect of the emulsion that embodiment 1,2 produces following with probation.Using public-opinion poll point system,
Choose 80 20-60 year age bracket women as object on probation, be arbitrarily divided into two groups, use the breast of embodiment 1,2 preparation respectively
Liquid is used for face.Daily using twice, use time is two months.Every using effect total score is 10 points：10 are divided into best result,
Represent very well, very satisfied；7-9 is divided into preferably；5-6 is divided into and can accept；Less than 5 points is bad it is impossible to accept.It is below each
Item average.The results are shown in Table 1：
Table 1 resultant effect investigation table
| Using effect | The every average of embodiment 1 | The every average of embodiment 2 |
| Palliative | 8.3 | 9.7 |
| Moistness | 7.6 | 8.9 |
| Moisture retention | 7.8 | 8.5 |
| Prosthetic | 8.8 | 9.5 |
| Fine and smooth sense | 9.3 | 9.0 |
In sum, this made emulsion of the present invention releive effect substantially, moisture retention, alimentary preferably, feel during use
Refrigerant comfortable, good with rear skin elasticity, have releive, effect that moisturizing, water are tender, fine and smooth.
Claims (7)
1. a kind of antiallergic releives reparation skin emulsion it is characterised in that 83.0g emulsion is by following material composition：
Semen pruni armeniacae oil 0.7-1.2g
Macadimia nut oil 0.8-1.3g
Semen Tritici aestivi germ oil 0.6-1.0g
Radix Oenotherae erythrosepalae oil 0.3-0.8g
All-round simple emulsifying agent 0.5-1.0g
Water solublity Jojoba oil 1.0-1.3g
Water solublity Ve 0.5-0.7g
Biological polyoses glue 1.0-1.2g
Cell vitalizing agent MG-60 1.0-1.2g
Amino acid humectant 0.5-0.6g
Trehalose 0.5-0.8g
Flos Chrysanthemi leaf extract 0.1-0.3g
Hibiscus syriacus L. leaf extract 0.2-0.5g
Radix Gentianae extracting solution 0.4-1.0g
Rhizoma Chuanxiong root extracting solution 0.4-1.0g
Mel 1.0-1.8g
Glycerol 1-4ml
1,2- propylene glycol 1-4ml
Distilled water 65.0-75.0g
Ethyl hydroxybenzoate 0.01-0.05g
Essence 0.01-0.05ml.
2. antiallergic according to claim 1 is releived and is repaired skin emulsion it is characterised in that described Flos Chrysanthemi leaf extract leads to
Cross in the following manner preparation：
Weigh Folium Chrysanthemi appropriate, after pulverizing, soak 30-50min, heat in 90-100 DEG C and decoct extraction 3 times, the 1st time plus 5-12 times
Amount water, extracts 0.5-2.5h, the 2nd time plus 4-10 times amount water, extracts 0.5-2.0h, the 3rd time plus 3-8 times amount water, extracts 0.5-
1.5h, filters every time, merging filtrate, 2-6 times of g/ml of the volume concentration of filtrate to Folium Chrysanthemi weight, filters and obtains final product Folium Chrysanthemi and carry
Take liquid.
3. antiallergic according to claim 1 is releived and is repaired skin emulsion it is characterised in that described Hibiscus syriacus L. leaf extract leads to
Cross following methods preparation：
Weigh Folium Hibisci appropriate, soak 30-50min, decoct in 90-100 DEG C of heating and extract 3 times, the 1st time plus 6-12 times amount water,
Extract 0.5-2h, the 2nd time plus 4-10 times amount water, extract 0.5-1.5h, the 3rd time plus 3-8 times amount water, extract 0.5-1.5h, every time
Filtration, merging filtrate, the volume concentration of filtrate, to 2-6 times of g/ml of Folium Hibisci weight, filters and obtains final product Hibiscus syriacus L. leaf extract.
4. antiallergic according to claim 1 is releived and is repaired skin emulsion it is characterised in that described Radix Gentianae extracting solution leads to
Cross in the following manner preparation：
Weigh Radix Gentianae appropriate, add 8-15 times of 70%-80% ethanol, reflux, extract, 0.5-2h, sucking filtration for the first time, add 8-15 second
Times 70%-80% ethanol, reflux, extract, 0.5-2h, sucking filtration, third time plus 6-10 times of 70%-80% ethanol, flow back 0.5-1.5h, takes out
Filter, three times filtrate merges, and the volume concentration of filtrate is 3-8 times of g/ml of medical material amount, obtains final product Radix Gentianae extracting solution.
5. antiallergic according to claim 1 is releived and is repaired skin emulsion it is characterised in that described Rhizoma Chuanxiong root extracting solution leads to
Cross in the following manner preparation：
After weighing the appropriate pulverizing of Rhizoma Chuanxiong root, soak 0.15-0.5h with ethanol, with the alcohol reflux of 8-15 times amount 50%-90%
0.5-2.5h, filters, then the alcohol reflux 0.5-2.5h with 8-15 times amount 50%-90%, filtration, then with 5-10 times amount 50%-
90% alcohol reflux 0.5-2.5h, filters, and three filtrates is merged, the decompression volume of filtrate is concentrated to the 4-7 of medical material amount
Times g/ml, obtains final product Rhizoma Chuanxiong root extracting solution.
6. antiallergic according to claim 1 is releived and is repaired skin emulsion it is characterised in that described essence is rose
Essence, peach flavor, flavoring pineapple essence, Fructus Citri Limoniae essence, green cucumber essence, jasmin essence, osmanthus flower fragrance.
7. the antiallergic described in a kind of claim 1 releives the preparation method repairing skin emulsion it is characterised in that described preparation side
Method comprises the following steps：
a）Weigh macadimia nut oil 0.8-1.3g, Semen pruni armeniacae oil 0.7-1.2g, Semen Tritici aestivi germ oil 0.6-1.0g, Radix Oenotherae erythrosepalae oil 0.3-
0.8g, simply emulsifying agent 0.5-1.0g all can be added in beaker, be put into heating in 70-95 DEG C of thermostat water bath, as molten
Liquid 1 is stand-by；
b）Weigh water solublity Jojoba oil 1.0-1.3g, water solublity Ve 0.5-0.7g, cell vitalizing agent MG-60 1.0-1.2g,
Amino acid humectant 0.5-0.6g, biological polyoses glue 1.0-1.2g, trehalose 0.5-0.8g, Mel 1.0-1.8g are added to beaker
In, it is eventually adding distilled water 65.0-75.0g and beaker is put in 70-95 DEG C of water-bath, stand-by as solution 2；
c）Treat that solution 1, solution 2 temperature are identical, solution 2 is slowly added in solution 1 with Glass rod drain, stirring while adding, directly
To forming homogeneous white milky liquid 3；
d）Ethyl hydroxybenzoate 0.01-0.05g is dissolved in glycerol 1-4ml, 1,2-PD 1-4ml, forms liquid 4；
e）Flos Chrysanthemi leaf extract 0.1-0.3g, Hibiscus syriacus L. leaf extract 0.2-0.5g, Radix Gentianae extracting solution is added toward in liquid 3
0.4-1.0g, Rhizoma Chuanxiong root extracting solution 0.4-1.0g, essence 0.01-0.05ml and liquid 4, with Glass rod stirring until emulsion is equal
Even, obtain final product antiallergic releive reparation skin emulsion.
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| CN108434063A (en) * | 2018-06-06 | 2018-08-24 | 华南协同创新研究院 | It is a kind of have effects that releive repair skin care compositions and the preparation and application of sensitive skin |
| CN108939139B (en) * | 2018-08-04 | 2021-02-02 | 浙江派菲特新材料科技有限公司 | Preparation method of medical adhesive with efficient anti-inflammatory and hemostatic functions |
| CN109758391A (en) * | 2018-12-06 | 2019-05-17 | 浙江大学自贡创新中心 | It is a kind of to have effects that the plant composition of antiallergic |
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| KR100990195B1 (en) * | 2010-01-20 | 2010-10-29 | (주)엘큐어 | Allergic or atopic dermatitis-alleviating natural cosmetic composition |
| CN102670478B (en) * | 2012-04-20 | 2013-06-12 | 诺斯贝尔(中山)无纺日化有限公司 | Multi-effect restoring skin cream |
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Inventor after: Li Meihua Inventor before: Sun Shuping Inventor before: Liu Xia Inventor before: Zhang Yuquan Inventor before: Qian Zhangchao Inventor before: Zhang Yuting |
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Effective date of registration: 20170516 Address after: Jianggao Mountain Industrial Park in Baiyun District of Guangzhou City, Guangdong province 510450 Zhenhua Road two cross road No. 78 Patentee after: Guangzhou Royal Cosmetics Co.,Ltd. Address before: 241002 Anhui, Yijiang Province Higher Education Park, Wenchang West Road, No. 22, No. Patentee before: Wannan Medical College |
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Address after: No.78 Zhenhua North Road, Jianggao Town, Baiyun District, Guangzhou City, Guangdong Province, 510000 Patentee after: Guangzhou Tianhao Cosmetics Co.,Ltd. Address before: No. 78 Zhenhua North Road, Erheng Road, Shenshan Industrial Park, Jianggao Town, Baiyun District, Guangzhou City, Guangdong Province, 510450 Patentee before: Guangzhou Royal Cosmetics Co.,Ltd. |
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