CN107184522A - A kind of skin antiallergic repair latex and preparation method thereof - Google Patents

A kind of skin antiallergic repair latex and preparation method thereof Download PDF

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Publication number
CN107184522A
CN107184522A CN201710273379.7A CN201710273379A CN107184522A CN 107184522 A CN107184522 A CN 107184522A CN 201710273379 A CN201710273379 A CN 201710273379A CN 107184522 A CN107184522 A CN 107184522A
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parts
skin
europe
repair latex
pine bark
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林彤
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Guangzhou Yuan Yuan Biotechnology Co Ltd
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Guangzhou Yuan Yuan Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
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  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The present invention discloses a kind of skin antiallergic repair latex and preparation method thereof, the composition of raw materials of the skin antiallergic repair latex, count by weight, it is by 1 part~2 parts French maritime pine bark extracts, 2 parts~4 portions mung bean zymotic fluids, 1 part~2 parts Europe rough gentian root extracts, 2 parts~4 parts saualanes, 3 parts~5 portions pseudo-ginseng, 4 parts~6 parts glucans, 10 parts~12 portions purslanes, 1 part~2 parts blue or green burs, 4 parts~6 portions radix glycyrrhizaes, 2 parts~4 parts fucoidins, 1 portion of Chinese herbaceous peony, 1 part of peach kernel, 1 part of perilla leaf, 2 parts~4 parts chamomiles, 15 parts~20 parts honey, the deionized water composition of 2 parts~4 parts ceramides and surplus.Emulsion of the present invention can releive skin, repair skin system of defense, skin metabolism passage is got through in promoting blood circulation, skin sensitivity, anti-inflammatory heat-clearing are reduced, and its formula uses pure Chinese medicine composition, environmental protection, to no skin irritation, long-term use can not only play a part of skin antiallergic, moreover it is possible to reappear skin health honorable.

Description

A kind of skin antiallergic repair latex and preparation method thereof
Technical field
The present invention relates to technique in skin care, more particularly to skin antiallergic recovery technique, and in particular to a kind of skin antiallergic Repair latex and preparation method thereof.
Background technology
Allergic is a kind of common allergy form, and according to investigations, the people that there are about 20% has phenomena of cutaneous irritation.Easily The skin of allergy is also known as sensitive.Various external causes cause skin to produce allergic reaction, it may appear that it is red and swollen, itch, peel and The anomalies such as allergic dermatitis.The allergic incidence of disease of China is very high, particularly in autumn and winter, dry skin, a lot People can show the allergic symptom such as pruitus.
Present environmental pollution is serious, and dust present in air, particle, harmful substance cause a certain degree of wound to skin Evil, pressure is big in life, stay up late, sitting, allow in face of many factors such as computer, endocrinopathies the skin of people seeking beauty for a long time Enjoy challenge.The smooth pale flexible skin of exquisiteness is that every people seeking beauty dreams of, even more sensitiveness skin crowd Yearned for, but sensitive skin allows people seeking beauty to enjoy limitation on the road of skin care.
It is in existing antiallergic product to contain hormonal components, although short-period used effect significantly, but can produce pair to body more Effect, is especially detrimental to the use of children, old man;And be used for a long time steroids antiallergic product can also produce dependence, it is resistance to The problems such as property of medicine.Therefore, research and development novel green safety, no steroids, and the significant skin-protection product of antiallergic effect, with important Realistic meaning and the wide market space.
The content of the invention
In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide a kind of green safety it is nontoxic, can effectively antiallergic repair The emulsion of multiple skin.
It is a further object to provide the preparation method of above-mentioned emulsion.
The above-mentioned purpose of the present invention is achieved by following scheme:
A kind of skin antiallergic repair latex, its composition of raw materials is made up of each component of following parts by weight:
1 part~2 parts of French maritime pine bark extract;
2 parts~4 parts of mung bean zymotic fluid;
1 part~2 parts of Europe rough gentian root extract;
2 parts~4 parts of saualane;
3 parts~5 parts of pseudo-ginseng;
Bextran 45 part~6 parts;
10 parts~12 parts of purslane;
Blue or green 1 part~2 parts of bur;
4 parts~6 parts of radix glycyrrhizae;
2 parts~4 parts of fucoidin;
1 part of Chinese herbaceous peony;
1 part of peach kernel;
1 part of perilla leaf;
2 parts~4 parts of chamomile;
15 parts~20 parts of honey;
Cer NS part~4 parts;
Surplus is deionized water.
A kind of composition of raw materials of above-mentioned skin antiallergic repair latex, is preferably made up of each component of following parts by weight:
1 part of French maritime pine bark extract;
3 parts of mung bean zymotic fluid;
1 part of Europe rough gentian root extract;
3 parts of saualane;
5 parts of pseudo-ginseng;
5 parts of glucan;
10 parts of purslane;
Blue or green 1 part of bur;
5 parts of radix glycyrrhizae;
3 parts of fucoidin;
1 part of Chinese herbaceous peony;
1 part of peach kernel;
1 part of perilla leaf;
3 parts of chamomile;
20 parts of honey;
Cer NP part;
Surplus is deionized water.
Pine Bark is the class material extracted from pine bark, and the pine bark peeled from pine tree is collected, stand It is gentle to extract;Have in Pine Bark and be largely referred to as OPCs(OPC oligomer)Compound;The France sea of the present invention Bank Pine Bark use comes from French coast pine Pine Bark, be specifically prepare by the following method and :Follow the example of state's maritime pine pine bark appropriate, 10 times of 75% ethanol solutions of amount are added for the first time(75% ethanol solution refers to volume hundred Divide the ethanol solution that specific concentration is 75%), refluxing extraction 1.5h, suction filtration, second plus 12 times of 80% ethanol solutions of amount(Described 80% Ethanol solution refers to the ethanol solution that concentration of volume percent is 80%), refluxing extraction 1h, suction filtration, concentration after filtrate merges twice Filtrate to relative density is 1.20(When the relative density is temperature 60 C), concentrate is spray-dried to obtain powdered substance, As French maritime pine bark extract.
Above-mentioned mung bean zymotic fluid is that the present invention can be achieved using commercially available mung bean zymotic fluid, it is preferred to use lactobacillus mung bean is sent out Zymotic fluid.
Europe rough gentian is Chinese medicine name, is rough gentian plant Europe rough gentian Gentiana luteaL. drying root and rhizome;The present invention Europe rough gentian root extract be to adopt to be prepared with the following method:Take Europe gentian appropriate, 20 mesh sieves are crossed after crushing, to Europe rough gentian Heating and refluxing extraction 1.5 hours after Extraction solvent are added in root crushed material, the temperature being heated to reflux is 70 DEG C, collects extract solution true Vacuum freecing-dry then obtains Europe rough gentian root extract to powder;The Extraction solvent is the ethanol that concentration of volume percent is 75% Solution, the solid-liquid ratio of the Europe gentian crushed material and Extraction solvent is 1:8, g/L.
Above-mentioned saualane also known as eepwater shark liver oil, which are that the squalene extracted from hydrogenated hydro carbons grease is hydrogenated, is made one Plant the squalene extracting of excellent performance.
Above-mentioned pseudo-ginseng, Chinese medicine name is the dry of panax araliaceae plant Panax notoginseng (Burk.) F.H.Chen Dry and rhizome.
Above-mentioned glucan uses beta glucan.
Above-mentioned purslane, Chinese medicine name is Portulacaceae annual herb plant, and herb hyoscine has clearing heat and promoting diuresis, removing toxic substances Detumescence, anti-inflammatory, quench the thirst, diuresis.
Above-mentioned blue or green bur, Chinese medicine name, fruit, can be used as medicine or eat at its root, leaf, with heat-clearing, removing toxic substances, promoting blood circulation, anti-inflammatory, Relieve pain, help digestion, the effect such as stomach invigorating.
Above-mentioned radix glycyrrhizae, Chinese medicine name belongs to perennial herb, medicinal part is root and rhizome.
Above-mentioned fucoidin is a kind of water-soluble polysaccharide being present in various brown algas.
Above-mentioned Chinese herbaceous peony is flower name, and its Peony Root can be used as medicine, and contain Paeoniflorin and benzoic acid isoreactivity composition.
Above-mentioned perilla leaf, is the band branch tender leaf of Labiatae purple perilla platymiscium purple perilla, the work(with expelling cold and relieving exterior syndrome, regulating the flow of QI to ease the stomach Effect.
The saualane of the present invention, pseudo-ginseng, glucan, purslane, blue or green bur, radix glycyrrhizae, fucoidin, Chinese herbaceous peony, peach kernel, Soviet Union Leaf, chamomile, honey and ceramide are that the present invention can be achieved using commercially available prod.
The skin antiallergic repair latex of the present invention, its preparation method comprises the following steps:
By pseudo-ginseng, French maritime pine bark extract, purslane, blue or green bur, radix glycyrrhizae, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile and Europe The deionized water of relative 2 times of amounts of mixture is added after the mixing of rough gentian root extract, autoclave, 120 DEG C of high-temperature sterilizations is then placed in 20min, is cooled to after 50 DEG C and adds honey, and 6-8 DEG C is stored sth. in a cellar 5 days, sealing and fermenting;Broken seal after fermentation ends and take supernatant to ferment Liquid, mung bean zymotic fluid, saualane and glucan are added into supernatant zymotic fluid, 80 DEG C is warming up to, 50 is cooled to after stirring and emulsifying DEG C, skin antiallergic repair latex needed for adding that ceramide is well mixed and then preparing;The rotating speed of the stirring and emulsifying is 50 turns/min, the time is 30min.
The skin antiallergic repair latex of the present invention, its quality is fine and smooth, and viscosity is suitable, and stretchability is good, and stability is good It is good, to no skin irritation.
Compared with prior art, the present invention has the advantages that:
1. the skin antiallergic repair latex of the present invention, its composition of raw materials uses Chinese medicine, environmental protection will not be caused to skin The problems such as excitant injury is also not in heavy-metal residual, hormone residues;
2. the extraction process of the skin antiallergic repair latex of the present invention, French maritime pine bark extract and Europe rough gentian root extract And its parameter selection, it has been effectively ensured after the other components of final extract collocation, has realized good product stability and skin can be repaired The effects such as preventing, reduce skin sensitivity;
3. in the preparation technology of skin antiallergic repair latex of the present invention, first by pseudo-ginseng, French maritime pine bark extract, dent High-temperature sterilization 20min after amaranth, blue or green bur, radix glycyrrhizae, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile and the mixing of Europe rough gentian root extract, then 6-8 DEG C is stored sth. in a cellar 5, and sealing and fermenting is equal to secondary fermentation, is conducive to the interaction of plurality of raw materials and is produced more micro Element;
The skin 4. the skin antiallergic repair latex of the present invention can releive, repairs skin system of defense, and skin metabolism is got through in promoting blood circulation Passage, reduces skin sensitivity, anti-inflammatory heat-clearing, long-term use can not only play a part of skin antiallergic, and it is strong to reappear skin Kang Guangcai.
Embodiment
The present invention is further described through with reference to specific embodiment, but specific embodiment is not appointed to the present invention What is limited.
The skin antiallergic repair latex of embodiment 1
The skin antiallergic repair latex of the present embodiment, its composition of raw materials is made up of each component of following parts by weight:
1 part of French maritime pine bark extract;
3 parts of mung bean zymotic fluid;
1 part of Europe rough gentian root extract;
3 parts of saualane;
5 parts of pseudo-ginseng;
5 parts of glucan;
10 parts of purslane;
Blue or green 1 part of bur;
5 parts of radix glycyrrhizae;
3 parts of fucoidin;
1 part of Chinese herbaceous peony;
1 part of peach kernel;
1 part of perilla leaf;
3 parts of chamomile;
20 parts of honey;
Cer NP part;
Surplus is deionized water.
Above-mentioned French maritime pine bark extract is to be prepared by the following method:Follow the example of state's maritime pine pine bark appropriate, The ethanol solution that first time plus 10 times of amount concentration of volume percent are 75%, refluxing extraction 1.5h, suction filtration adds 12 times of amounts for the second time Concentration of volume percent is 80% ethanol solution, refluxing extraction 1h, suction filtration, and concentration filtrate is to relatively close after filtrate merges twice Spend for 1.20(Temperature 60 C), concentrate is spray-dried to obtain powdered substance, as French maritime pine bark extract.
Above-mentioned mung bean zymotic fluid uses commercially available mung bean zymotic fluid.
Above-mentioned Europe rough gentian root extract is prepared using following method:Take Europe gentian appropriate, 20 mesh sieves crossed after crushing, Heating and refluxing extraction 1.5 hours after Extraction solvent are added into Europe gentian crushed material, the temperature being heated to reflux is 70 DEG C, is collected Extract solution vacuum freeze drying then obtains Europe rough gentian root extract to powder;The Extraction solvent is that concentration of volume percent is 75% ethanol solution, the solid-liquid ratio of the Europe gentian crushed material and Extraction solvent is 1:8, g/L.
Above-mentioned glucan uses commercially available beta glucan.
Above-mentioned saualane, pseudo-ginseng, purslane, blue or green bur, radix glycyrrhizae, fucoidin, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile, honeybee Honey and ceramide use commercially available Chinese medicine or product.
Above-mentioned skin antiallergic repair latex, its preparation method comprises the following steps:
By pseudo-ginseng, French maritime pine bark extract, purslane, blue or green bur, radix glycyrrhizae, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile and Europe The deionized water of relative 2 times of amounts of mixture is added after the mixing of rough gentian root extract, autoclave, 120 DEG C of high-temperature sterilizations is then placed in 20min, is cooled to after 50 DEG C and adds honey, and 6-8 DEG C is stored sth. in a cellar 5 days, sealing and fermenting;Broken seal after fermentation ends and take supernatant to ferment Liquid, mung bean zymotic fluid, saualane and glucan are added into supernatant zymotic fluid, 80 DEG C is warming up to, 50 is cooled to after stirring and emulsifying DEG C, skin antiallergic repair latex needed for adding that ceramide is well mixed and then preparing;The rotating speed of the stirring and emulsifying is 50 turns/min, the time is 30min.
The skin antiallergic repair latex of embodiment 2
The skin antiallergic repair latex of the present embodiment, its composition of raw materials is made up of each component of following parts by weight:
1.5 parts of French maritime pine bark extract;
4 parts of mung bean zymotic fluid;
1.5 parts of Europe rough gentian root extract;
2 parts of saualane;
3 parts of pseudo-ginseng;
Bextran 45 part;
12 parts of purslane;
Blue or green 2 parts of bur;
4 parts of radix glycyrrhizae;
2 parts of fucoidin;
1 part of Chinese herbaceous peony;
1 part of peach kernel;
1 part of perilla leaf;
2 parts of chamomile;
18 parts of honey;
Cer NP part;
Surplus is deionized water.
Above-mentioned French maritime pine bark extract is to be prepared by the following method:Follow the example of state's maritime pine pine bark appropriate, The ethanol solution that first time plus 10 times of amount concentration of volume percent are 75%, refluxing extraction 1.5h, suction filtration adds 12 times of amounts for the second time Concentration of volume percent is 80% ethanol solution, refluxing extraction 1h, suction filtration, and concentration filtrate is to relatively close after filtrate merges twice Spend for 1.20(Temperature 60 C), concentrate is spray-dried to obtain powdered substance, as French maritime pine bark extract.
Above-mentioned mung bean zymotic fluid uses commercially available mung bean zymotic fluid.
Above-mentioned Europe rough gentian root extract is prepared using following method:Take Europe gentian appropriate, 20 mesh sieves crossed after crushing, Heating and refluxing extraction 1.5 hours after Extraction solvent are added into Europe gentian crushed material, the temperature being heated to reflux is 70 DEG C, is collected Extract solution vacuum freeze drying then obtains Europe rough gentian root extract to powder;The Extraction solvent is that concentration of volume percent is 75% ethanol solution, the solid-liquid ratio of the Europe gentian crushed material and Extraction solvent is 1:8, g/L.
Above-mentioned glucan uses commercially available beta glucan.
Above-mentioned saualane, pseudo-ginseng, purslane, blue or green bur, radix glycyrrhizae, fucoidin, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile, honeybee Honey and ceramide use commercially available Chinese medicine or product.
Above-mentioned skin antiallergic repair latex, its preparation method comprises the following steps:
By pseudo-ginseng, French maritime pine bark extract, purslane, blue or green bur, radix glycyrrhizae, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile and Europe The deionized water of relative 2 times of amounts of mixture is added after the mixing of rough gentian root extract, autoclave, 120 DEG C of high-temperature sterilizations is then placed in 20min, is cooled to after 50 DEG C and adds honey, and 6-8 DEG C is stored sth. in a cellar 5 days, sealing and fermenting;Broken seal after fermentation ends and take supernatant to ferment Liquid, mung bean zymotic fluid, saualane and glucan are added into supernatant zymotic fluid, 80 DEG C is warming up to, 50 is cooled to after stirring and emulsifying DEG C, skin antiallergic repair latex needed for adding that ceramide is well mixed and then preparing;The rotating speed of the stirring and emulsifying is 50 turns/min, the time is 30min.
The skin antiallergic repair latex of embodiment 3
The skin antiallergic repair latex of the present embodiment, its composition of raw materials is made up of each component of following parts by weight:
2 parts of French maritime pine bark extract;
2 parts of mung bean zymotic fluid;
2 parts of Europe rough gentian root extract;
4 parts of saualane;
4 parts of pseudo-ginseng;
6 parts of glucan;
11 parts of purslane;
Blue or green 1 part of bur;
6 parts of radix glycyrrhizae;
4 parts of fucoidin;
1 part of Chinese herbaceous peony;
1 part of peach kernel;
1 part of perilla leaf;
4 parts of chamomile;
15 parts of honey;
Cer NS part;
Surplus is deionized water.
Above-mentioned French maritime pine bark extract is to be prepared by the following method:Follow the example of state's maritime pine pine bark appropriate, The ethanol solution that first time plus 10 times of amount concentration of volume percent are 75%, refluxing extraction 1.5h, suction filtration adds 12 times of amounts for the second time Concentration of volume percent is 80% ethanol solution, refluxing extraction 1h, suction filtration, and concentration filtrate is to relatively close after filtrate merges twice Spend for 1.20(Temperature 60 C), concentrate is spray-dried to obtain powdered substance, as French maritime pine bark extract.
Above-mentioned mung bean zymotic fluid uses commercially available mung bean zymotic fluid.
Above-mentioned Europe rough gentian root extract is prepared using following method:Take Europe gentian appropriate, 20 mesh sieves crossed after crushing, Heating and refluxing extraction 1.5 hours after Extraction solvent are added into Europe gentian crushed material, the temperature being heated to reflux is 70 DEG C, is collected Extract solution vacuum freeze drying then obtains Europe rough gentian root extract to powder;The Extraction solvent is that concentration of volume percent is 75% ethanol solution, the solid-liquid ratio of the Europe gentian crushed material and Extraction solvent is 1:8, g/L.
Above-mentioned glucan uses commercially available beta glucan.
Above-mentioned saualane, pseudo-ginseng, purslane, blue or green bur, radix glycyrrhizae, fucoidin, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile, honeybee Honey and ceramide use commercially available Chinese medicine or product.
Above-mentioned skin antiallergic repair latex, its preparation method comprises the following steps:
By pseudo-ginseng, French maritime pine bark extract, purslane, blue or green bur, radix glycyrrhizae, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile and Europe The deionized water of relative 2 times of amounts of mixture is added after the mixing of rough gentian root extract, autoclave, 120 DEG C of high-temperature sterilizations is then placed in 20min, is cooled to after 50 DEG C and adds honey, and 6-8 DEG C is stored sth. in a cellar 5 days, sealing and fermenting;Broken seal after fermentation ends and take supernatant to ferment Liquid, mung bean zymotic fluid, saualane and glucan are added into supernatant zymotic fluid, 80 DEG C is warming up to, 50 is cooled to after stirring and emulsifying DEG C, skin antiallergic repair latex needed for adding that ceramide is well mixed and then preparing;The rotating speed of the stirring and emulsifying is 50 turns/min, the time is 30min.
Comparative example
The formula and each component be the same as Example 1 of comparative example skin antiallergic repair latex, its preparation method is by pseudo-ginseng, France Maritime pine bark extract, purslane, blue or green bur, radix glycyrrhizae, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile and the mixing of Europe rough gentian root extract The deionized water of relative 2 times of amounts of mixture is added afterwards, is then placed in autoclave, 120 DEG C of high-temperature sterilization 20min are cooled to 50 DEG C After add honey, room temperature(25 DEG C or so)Place 5, take supernatant to add mung bean zymotic fluid, saualane and glucan, be warming up to 80 DEG C, 50 DEG C are cooled to after stirring and emulsifying, skin antiallergic needed for adding that ceramide is well mixed and then preparing repairs breast Liquid;The rotating speed of the stirring and emulsifying is 50 turns/min, and the time is 30min.
The stability experiment of embodiment 4
Skin antiallergic repair latex prepared by embodiment 1,2 and 3 is put into bottle for cosmetics, is stored at room temperature 3 months, observes emulsion Without lamination, and when using, emulsion is still fine and smooth, easy to apply, and odorlessness changes, skin also stingless excitation.
Skin antiallergic repair latex prepared by comparative example is put into bottle for cosmetics, is stored at room temperature 3 months, observes emulsion There is lamination.
The clinical test of embodiment 5
Choose 60 16-50 Sui there is skin to itch, the patient of the phenomena of cutaneous irritation such as blister, red blood silk, men and women do not limit, is divided into 3 groups, every group of 20 people, skin antiallergic reparation prepared by the skin antiallergic repair latex prepared respectively using embodiment 1, embodiment 2 Emulsion, skin antiallergic repair latex prepared by comparative example, emulsion is smeared once respectively sooner or later, continuous to use 2 months.
Judgment criteria:Itch if skin, the phenomena of cutaneous irritation such as blister, red blood silk, papule disappears or is if substantially mitigating Effectively;Itch if skin, the phenomena of cutaneous irritation change such as blister, red blood silk, papule substantially if to be invalid.
As a result:The experimental group effective percentage of the skin antiallergic repair latex of embodiment 1 is used for 100%, and experimenter reacts skin Skin is without any irritative response;The experimental group effective percentage of the skin antiallergic repair latex of embodiment 2 is used for 100%, and experimenter is equal Skin is reacted without any irritative response;The experimental group effective percentage of comparative example skin antiallergic repair latex is used for 50%, and Experimenter reacts skin without any irritative response.
Model case:
1st, patient:23 years old, there is itch, blister symptom after dermal application cosmetics in Liu, female, anti-using skin of the present invention The pruritis disappearance after 3 days of quick repair latex, blister symptom is wholly absent after 1 month.
2nd, patient:Certain is gone into business, female, 45 years old, due to bad cosmetics and beauty apparatus is used for a long time, skin was very thin, and redness is itched, Cell tissue liquid seepage sometimes.Using antiallergic repair latex of the present invention 60 days, skin was significantly taken on a new look, swollen to itch Symptom disappears, the red decline of face, does not occur cell tissue liquid Seepage again.
3rd, patient, Chen, man 35 years old, due to causing steroid dependent dermatitis to break out using steroids facial mask, shows as mesh There are a large amount of papules in lower cheek malar, and redness is itched.Itched disappearance using redness after skin antiallergic repair latex of the present invention 28 days, Skin starts to cast off a skin, and is continuing with skin exquisiteness gloss after 10 days, half steroid dependent dermatitis does not recur within 1 year so far.

Claims (7)

1. a kind of skin antiallergic repair latex, it is characterised in that the composition of raw materials of the emulsion is by each component of following parts by weight Composition:
1 part~2 parts of French maritime pine bark extract;
2 parts~4 parts of mung bean zymotic fluid;
1 part~2 parts of Europe rough gentian root extract;
2 parts~4 parts of saualane;
3 parts~5 parts of pseudo-ginseng;
Bextran 45 part~6 parts;
10 parts~12 parts of purslane;
Blue or green 1 part~2 parts of bur;
4 parts~6 parts of radix glycyrrhizae;
2 parts~4 parts of fucoidin;
1 part of Chinese herbaceous peony;
1 part of peach kernel;
1 part of perilla leaf;
2 parts~4 parts of chamomile;
15 parts~20 parts of honey;
Cer NS part~4 parts;
Surplus is deionized water.
2. skin antiallergic repair latex according to claim 1, it is characterised in that the composition of raw materials of the emulsion is by weighing as follows Measure each component composition of number:
1 part of French maritime pine bark extract;
3 parts of mung bean zymotic fluid;
1 part of Europe rough gentian root extract;
3 parts of saualane;
5 parts of pseudo-ginseng;
5 parts of glucan;
10 parts of purslane;
Blue or green 1 part of bur;
5 parts of radix glycyrrhizae;
3 parts of fucoidin;
1 part of Chinese herbaceous peony;
1 part of peach kernel;
1 part of perilla leaf;
3 parts of chamomile;
20 parts of honey;
Cer NP part;
Surplus is deionized water.
3. skin antiallergic repair latex according to claim 1 or claim 2, it is characterised in that the French maritime pine bark extract Preparation method be to follow the example of that state's maritime pine pine bark is appropriate, for the first time plus 10 times of amount concentration of volume percent are molten for 75% ethanol Liquid, refluxing extraction 1.5h, suction filtration, the ethanol solution that second plus 12 times of amount concentration of volume percent are 80%, refluxing extraction 1h, Suction filtration, concentration filtrate to relative density is 1.20 after filtrate merges twice, when the relative density is temperature 60 C, by concentrate It is spray-dried to obtain powdered substance, as French maritime pine bark extract.
4. skin antiallergic repair latex according to claim 1 or claim 2, it is characterised in that the preparation of the Europe rough gentian root extract Method is to take Europe gentian appropriate, and 20 mesh sieves are crossed after crushing, and it is 75% that concentration of volume percent is added into Europe gentian crushed material Ethanol solution heating and refluxing extraction 1.5 hours, the temperature being heated to reflux is 70 DEG C, collects extract solution vacuum freeze drying to powder End, then obtain Europe rough gentian root extract.
5. skin antiallergic repair latex according to claim 4, it is characterised in that the preparation side of the Europe rough gentian root extract In method, the solid-liquid ratio for the ethanol solution that Europe gentian crushed material and concentration of volume percent are 75% is 1:8, g/L.
6. a kind of preparation method of any one skin antiallergic repair latex described in claim 1-5, it is characterised in that the preparation side Method comprises the following steps:
By pseudo-ginseng, French maritime pine bark extract, purslane, blue or green bur, radix glycyrrhizae, Chinese herbaceous peony, peach kernel, perilla leaf, chamomile and Europe The deionized water of relative 2 times of amounts of mixture is added after the mixing of rough gentian root extract, autoclave, 120 DEG C of high-temperature sterilizations is then placed in 20min, is cooled to after 50 DEG C and adds honey, and 6-8 DEG C is stored sth. in a cellar 5 days, sealing and fermenting;Broken seal after fermentation ends and take supernatant to ferment Liquid, mung bean zymotic fluid, saualane and glucan are added into supernatant zymotic fluid, 80 DEG C is warming up to, 50 is cooled to after stirring and emulsifying DEG C, skin antiallergic repair latex needed for adding that ceramide is well mixed and then preparing.
7. the preparation method of skin antiallergic repair latex according to claim 6, it is characterised in that the stirring and emulsifying turns Speed is 50 turns/min, and the time is 30min.
CN201710273379.7A 2017-04-25 2017-04-25 A kind of skin antiallergic repair latex and preparation method thereof Pending CN107184522A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108143702A (en) * 2018-03-02 2018-06-12 大饼少女美妆(广州)有限公司 A kind of efficient whitening and moisturizing facial mask liquid, facial mask and preparation method thereof
CN108272686A (en) * 2018-03-30 2018-07-13 徐文豪 A kind of sunflower oil massage emulsion
CN109106667A (en) * 2018-09-19 2019-01-01 连云港本草美汇医药科技有限公司 A kind of anti-inflammatory Shu Min Chinese medicine composition emulsion and the preparation method and application thereof
CN109363984A (en) * 2018-10-18 2019-02-22 浙江大学自贡创新中心 A kind of prinsepia utilis royle oil dregs of rice fermentation liquid and preparation method thereof and the application in cosmetics
CN109363984B (en) * 2018-10-18 2022-03-11 浙江大学自贡创新中心 Prinsepia utilis royle oil meal fermentation liquor, preparation method thereof and application thereof in cosmetics
CN111214427A (en) * 2020-02-29 2020-06-02 宁波法迪曼生物工程有限公司 Acid-free skin refreshing composition, preparation method thereof and essence containing composition
CN111388398A (en) * 2020-04-13 2020-07-10 佛山秘码中医馆有限公司 Chinese herbal medicine liquid for increasing skin barrier function
CN114259437A (en) * 2021-12-14 2022-04-01 广州杨森药业有限公司 Plant fresh-raising dew soothing and repairing composition and preparation method and application thereof
CN117137104A (en) * 2023-09-04 2023-12-01 桉伽(天津)国际贸易有限公司 Honey composition with repairing promoting and antioxidant functions and preparation method and application thereof

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