CN105055849A - Traditional Chinese medicine extract capable of nourishing Yin and tonifying kidney as well as preparation method and application of traditional Chinese medicine extract - Google Patents
Traditional Chinese medicine extract capable of nourishing Yin and tonifying kidney as well as preparation method and application of traditional Chinese medicine extract Download PDFInfo
- Publication number
- CN105055849A CN105055849A CN201510448269.0A CN201510448269A CN105055849A CN 105055849 A CN105055849 A CN 105055849A CN 201510448269 A CN201510448269 A CN 201510448269A CN 105055849 A CN105055849 A CN 105055849A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- chinese medicine
- medicine extract
- kidney
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a traditional Chinese medicine extract capable of nourishing Yin and tonifying kidney as well as a preparation method and an application of the traditional Chinese medicine extract. The traditional Chinese medicine extract is prepared from the following active ingredients in parts by weight: 4-13 parts of astragalus membranaceus, 5-11 parts of codonopsis pilosula, 6-14 parts of lucid ganoderma, 1-5 parts of lucid ganoderma, 1-8 parts of radix paeoniae alba, 1-5 parts of the root of red-rooted salvia, 2-7 parts of radix ophiopogonis, 1-6 parts of schisandra chinensis, 2-7 parts of fruits of Chinese wolfberry, 1-8 parts of the seeds of Chinese dodder, 2-7 parts of teasel root, 1-5 parts of eucommia ulmoides, 1-8 parts of the root of bidentate achyranthes, 2-7 parts of herba epimedii, 1-7 parts of solomon's seal, 2-7 parts of dogwood, 1-6 parts of mulberries, 1-5 parts of liquorice, and 15-25 parts of acanthopanax. The traditional Chinese medicine extract as the functional component is prepared into massage cream together with substances or carriers frequently used in cosmetics, the defects of oral drugs are overcome, the massage cream is convenient to use, and free of toxic or side effect, and has the obvious efficiencies of nourishing Yin and tonifying kidney.
Description
Technical field
The invention belongs to Chinese medicine external product field, the massage cream particularly relating to a kind of YIN nourishing Chinese medicine extract of supporting kidney and preparation method thereof and be main composition with this Chinese medicine extract.
Background technology
The traditional Chinese medical science thinks that kidney is " the congenital foundation, the root of the day after tomorrow ".Kidney storing essence, essence can be changed into QI, edema caused by disorder of QI negative and positive.Kidney yin plays a part to nourish, make moist to internal organs organ, is the basic of the cloudy liquid of human body; Kidney yang to zang-fu differentiation histoorgan play a part promote, warm, be the basic of human body.Kidney yin and kidney yang are all material base with kidney essense, maintain the relative equilibrium of overall negative and positive.Suffer from a deficiency of the kidney and mostly be essence, gas, yin, yang loss, can lose, day after tomorrow not enough because of natural endowment support, overwork, intemperate sexual intercourse, caused by prolonged illness loss etc.Common deficiency of kidney-essence card has: syndrome of deficiency of kidney-YANG, syndrome of deficiency of kidney yin, syndrome of non-consolidation of kidney qi, edema due to deficiency of the kidney card and failure of the kidney in receiving QI card.Suffer from a deficiency of the kidney and relate to the different pathological stages of multiple systemic diseases such as the heart, brain, lung, kidney, liver, especially comparatively outstanding in the intermediary and later stages of the diseases such as chronic nephritis, diabetes, hypertension.Therefore, the Chinese medicine extract of supporting kidney to YIN nourishing carries out correlational study exploitation and has great importance.
The medicine great majority that at present YIN nourishing supports kidney are on the market based on oral drugs, and Oral administration exists the first pass effect of liver and intestinal to the destruction of medicine, and the absorbance of medicine is reduced, and the course for the treatment of is long, and has side effect.And externally used paste percutaneous dosing, containing liver and kidney tonifying, nourishing blood to promote the production of body fluid, convergence is astringent or styptic treatment for spontaneous sweating, bone and muscle strengthening is primary efficacy Effective Component of Chinese Medicine targeting infiltration SHENYU point, to reach the beneficial effect that YIN nourishing supports kidney.External massage cream Be very effective, have no side effect, easy to use, become people make earnest efforts select administering mode.
Summary of the invention
Based on this, an object of the present invention is to provide the Chinese medicine extract that a kind of YIN nourishing supports kidney.
In order to realize foregoing invention object, this invention takes following technical scheme:
YIN nourishing supports a Chinese medicine extract for kidney, and the active component of described Chinese medicine extract is prepared from by the raw material of following weight portion: Radix Astragali 4-13 part, Radix Codonopsis 5-11 part, Ganoderma 6-14 part, Radix Angelicae Sinensis 1-5 part, Radix Paeoniae Alba 1-8 part, Radix Salviae Miltiorrhizae 1-5 part, Radix Ophiopogonis 2-7 part, Fructus Schisandrae Chinensis 1-6 part, Fructus Lycii 2-7 part, Semen Cuscutae 1-8 part, Radix Dipsaci 2-7 part, Cortex Eucommiae 1-5 part, Radix Achyranthis Bidentatae 1-8 part, Herba Epimedii 2-7 part, Rhizoma Polygonati 1-7 part, Fructus Corni 2-7 part, Fructus Mori 1-6 part, Radix Glycyrrhizae 1-5 part, Radix Et Caulis Acanthopanacis Senticosi 15-25 part.
Wherein in some embodiments, the active component of described Chinese medicine extract is prepared from by the raw material of following weight portion: Radix Astragali 7-9 part, Radix Codonopsis 7-9 part, Ganoderma 7-9 part, Radix Angelicae Sinensis 2-4 part, Radix Paeoniae Alba 4-6 part, Radix Salviae Miltiorrhizae 2-4 part, Radix Ophiopogonis 3-6 part, Fructus Schisandrae Chinensis 2-4 part, Fructus Lycii 3-5 part, Semen Cuscutae 3-5 part, Radix Dipsaci 3-5 part, Cortex Eucommiae 2-4 part, Radix Achyranthis Bidentatae 2-5 part, Herba Epimedii 3-5 part, Rhizoma Polygonati 2-6 part, Fructus Corni 3-5 part, Fructus Mori 2-4 part, Radix Glycyrrhizae 2-4 part, Radix Et Caulis Acanthopanacis Senticosi 18-22 part.
Wherein in an embodiment, the active component of described Chinese medicine extract is prepared from by the raw material of following weight portion: the Radix Astragali 8 parts, Radix Codonopsis 8 parts, Ganoderma 8 parts, Radix Angelicae Sinensis 3 parts, the Radix Paeoniae Alba 4 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Ophiopogonis 4 parts, Fructus Schisandrae Chinensis 2 parts, Fructus Lycii 4 parts, Semen Cuscutae 4 parts, Radix Dipsaci 4 parts, the Cortex Eucommiae 3 parts, Radix Achyranthis Bidentatae 4 parts, Herba Epimedii 4 parts, Rhizoma Polygonati 4 parts, Fructus Corni 4 parts, Fructus Mori 3 parts, 2 parts, Radix Glycyrrhizae, Radix Et Caulis Acanthopanacis Senticosi 20 parts.
Each component pharmacological action of Chinese medicine extract of the present invention is as follows:
The Radix Astragali: sweet, tepor, tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promotes the production of body fluid and nourishes blood, the stagnant blood stasis dispelling of row, weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and arthralgia pain is numb.
Radix Codonopsis: sweet, flat, spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid, for deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, interior-heat is quenched one's thirst.
Ganoderma: sweet, flat, invigorating QI and tranquilization, for malaise, insomnia cardiopalmus, asthenia is losed heart, anorexia.
Radix Angelicae Sinensis: sweet, pungent, warm, enriches blood and invigorates blood circulation, menstruction regulating and pain relieving, for blood deficiency and yellow complexion, and dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down.
The Radix Paeoniae Alba: bitter, acid, to be slightly cold, nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, for blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, has a headache dizzy.
Radix Salviae Miltiorrhizae: bitter, is slightly cold, blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, and clear away heart-fire relieving restlessness, for obstruction of qi in the chest and cardialgia, and gastral cavity abdomen hypochondriac pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea.
Radix Ophiopogonis: sweet, micro-hardship, is slightly cold, YIN nourishing and the production of body fluid promoting, and lung moistening clears away heart-fire, and coughs for deficiency of YIN consumptive disease, it is thirsty that order is hindered in Tianjin, and interior-heat is quenched one's thirst, vexed insomnia.
Fructus Schisandrae Chinensis: sour, sweet, temperature, restrains astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming, and for emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, it is thirsty that day is hindered in Tianjin, and interior-heat is quenched one's thirst, palpitation and insomnia.
Fructus Lycii: sweet, flat, nourishing the liver and kidney, replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, impotence and seminal emission, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Semen Cuscutae: pungent, sweet, flat, liver and kidney tonifying, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, antidiarrheal, uses dry deficiency of the liver and kindey, soreness of the waist and knees, impotence and seminal emission, enuresis frequent micturition, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, blurred vision tinnitus, and spleen is suffered from a deficiency of the kidney and rushed down.
Radix Dipsaci: bitter, pungent, tepor, bone and muscle strengthening, continuous injured, only metrorrhagia, for deficiency of the liver and kindey, soreness of the waist and knees, injury from falling down, the injury of tendon and muscle is fractured, metrorrhagia, vaginal bleeding during pregnancy.
The Cortex Eucommiae: sweet, temperature, invigorating the liver and kidney, bone and muscle strengthening, antiabortive, for deficiency of the liver and kindey, soreness of waist and knee joint, muscles and bones is unable, has a dizzy spell, blood leaking in gestation, frequent fetal movement.
Radix Achyranthis Bidentatae: bitter, sweet, sour, flat, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards, for amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable.
Herba Epimedii: acrid, sweet, warm, kidney-replenishing, bone and muscle strengthening, wind-damp dispelling, for kidney yang deficiency, impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture.
Rhizoma Polygonati: sweet, flat, boosting qi and nourishing yin, kidney tonifying, for deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, asthenia of essence and blood, soreness of the waist and knees, interior-heat is quenched one's thirst.
Fructus Corni: sour, puckery, tepor, liver and kidney tonifying, arresting collape syndrome by astringents, for vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed, and interior-heat is quenched one's thirst.
Fructus Mori: sweet, sour, cold, nourishing YIN and supplementing blood, promotes the production of body fluid and moisturizes, and for the hepatic and renal YIN deficiency, vertigo and tinnitus, palpitation and insomnia, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.
Radix Glycyrrhizae: sweet, flat, invigorating the spleen and replenishing QI, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, the anxious pain of gastral cavity abdomen, extremity contraction.
Radix Et Caulis Acanthopanacis Senticosi: pungent, micro-hardship, temperature, tonifying the kidney for tranquilization, weak for body void, deficiency of both the lung and kidney, soreness of waist and knee joint of suffering from a deficiency of the kidney.
Another object of the present invention is to provide above-mentioned YIN nourishing to support the preparation method of kidney Chinese medicine extract.
Concrete technical scheme is as follows:
Above-mentioned YIN nourishing supports a preparation method for kidney Chinese medicine extract, comprises the following steps: take described raw material by proportioning, pulverizes, extract with water or alcoholic solution, by extracting solution, centrifugal or filtration, obtains centrifugal liquid or filtrate, by centrifugal liquid or filtrate reduced in volume, obtain described Chinese medicine extract.
Wherein in some embodiments, the method for described extraction is water boiling and extraction method, ethanol ultrasonic extraction method or ethanol percolate extraction method.
Wherein in some embodiments, the consumption of described water or alcoholic solution is 6-10 times of medical material weight, and the mass fraction of alcoholic solution is 25-65%; Described concentrating under reduced pressure is for being concentrated into raw material: the weight ratio of concentrated solution is 1:0.5.
Another object of the present invention is to the application that above-mentioned Chinese medicine extract is provided.
Concrete technical scheme is as follows:
Above-mentioned Chinese medicine extract has YIN nourishing in preparation and supports application in the Chinese medicine external product of kidney effect.
Another object of the present invention is to provide a kind of YIN nourishing to support the massage cream of kidney.
Concrete technical scheme is as follows:
YIN nourishing supports a massage cream for kidney, by as main composition above-mentioned Chinese medicine extract and substrate commonly used by cosmetics or carrier is prepared from.
Wherein in some embodiments, described massage cream is prepared from by the raw material of following percentage by weight: 20% above-mentioned Chinese medicine extract, 1.8% stereth-2, 2.0% stereth-21, 3.5% glyceryl stearate, 4.5% cetearyl alcohol, 5.0% dicaprylyl carbonate, 5.0% isopropyl myristate, 2.0% polydimethylsiloxane, 0.1% tocopherol acetas, 0.05% bisabolol, 37.48% water, 8.0%1, ammediol, 0.3% xanthan gum, 0.2% sodium alginate, 0.05% disodiumedetate, 1.0% betanin, 0.1% allantoin, 0.2% pantothenylol, 0.5% titanium dioxide, 5.0% glycerol, 2.0% butanediol, 0.02% tetrahydrochysene piperine, 0.6% Methylisothiazolinone/chlorphenesin, 0.5% phenoxyethanol/Sensiva SC50, 0.1% essence.
The present invention has following beneficial effect:
Chinese medicine extract provided by the invention has tonifying the kidney for tranquilization, liver nourishing is nourished blood, the effect of invigorating the spleen and benefiting QI, can effectively delay the symptoms such as dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, hectic fever night sweat, dysphoria with feverish sensation in the chest palms and soles.Substrate conventional in this Chinese medicine extract and cosmetics or carrier are prepared into external massage cream, the YIN nourishing overcome in above-mentioned background technology supports the deficiency of kidney oral drugs, described massage cream has no side effect, easy to use, by the mode of percutaneous dosing, the infiltration of effective ingredient targeting Guanyuan acupoint, MINGMEN acupoint, SHENYU point in Chinese medicine extract, to reach the remarkable result that YIN nourishing supports kidney.
Detailed description of the invention
Below with reference to specific embodiment, the invention will be further described.
Embodiment 1 one kinds of YIN nourishing support the Chinese medicine extract of kidney
The Chinese medicine extract that the YIN nourishing of the present embodiment supports kidney is prepared from by the raw material of following weight portion: the Radix Astragali 4 parts, Radix Codonopsis 5 parts, Ganoderma 14 parts, Radix Angelicae Sinensis 1 part, the Radix Paeoniae Alba 1 part, Radix Salviae Miltiorrhizae 5 parts, Radix Ophiopogonis 7 parts, Fructus Schisandrae Chinensis 6 parts, Fructus Lycii 2 parts, Semen Cuscutae 8 parts, Radix Dipsaci 2 parts, the Cortex Eucommiae 1 part, Radix Achyranthis Bidentatae 8 parts, Herba Epimedii 2 parts, Rhizoma Polygonati 1 part, Fructus Corni 7 parts, Fructus Mori 6 parts, 1 part, Radix Glycyrrhizae, Radix Et Caulis Acanthopanacis Senticosi 25 parts.
The preparation method of the Chinese medicine extract of the present embodiment is as follows:
Above-mentioned Chinese crude drug is taken by proportioning, pulverize, add medical material weight 8 times amount, mass fraction be 25% alcoholic solution supersound extraction 2 times, merge 2 extracting solution, extracting solution low-speed centrifugal, high speed centrifugation in centrifugal liquid, collect high speed centrifugation liquid, concentrating under reduced pressure, is concentrated into medical material: the weight ratio of concentrated solution is 1:0.5, must have the Chinese medicine extract that YIN nourishing supports kidney effect.
Embodiment 2 one kinds of YIN nourishing support the Chinese medicine extract of kidney
The Chinese medicine extract that the YIN nourishing of the present embodiment supports kidney is prepared from by the raw material of following weight portion: the Radix Astragali 13 parts, Radix Codonopsis 11 parts, Ganoderma 6 parts, Radix Angelicae Sinensis 5 parts, the Radix Paeoniae Alba 8 parts, Radix Salviae Miltiorrhizae 1 part, Radix Ophiopogonis 2 parts, Fructus Schisandrae Chinensis 1 part, Fructus Lycii 7 parts, Semen Cuscutae 1 part, Radix Dipsaci 7 parts, the Cortex Eucommiae 5 parts, Radix Achyranthis Bidentatae 1 part, Herba Epimedii 7 parts, Rhizoma Polygonati 7 parts, Fructus Corni 2 parts, Fructus Mori 1 part, 5 parts, Radix Glycyrrhizae, Radix Et Caulis Acanthopanacis Senticosi 15 parts.
The preparation method of the Chinese medicine extract of the present embodiment is as follows:
Take above-mentioned Chinese crude drug by proportioning, pulverize, add the water boiling and extraction 2 times of medical material weight 6 times amount, extracting solution filters, and is concentrated into medical material: the weight ratio of concentrated solution is 1:0.5, must have the Chinese medicine extract that YIN nourishing supports kidney effect.
Embodiment 3 one kinds of YIN nourishing support the Chinese medicine extract of kidney
The Chinese medicine extract that the YIN nourishing of the present embodiment supports kidney is prepared from by the raw material of following weight portion: the Radix Astragali 8 parts, Radix Codonopsis 8 parts, Ganoderma 8 parts, Radix Angelicae Sinensis 3 parts, the Radix Paeoniae Alba 4 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Ophiopogonis 4 parts, Fructus Schisandrae Chinensis 2 parts, Fructus Lycii 4 parts, Semen Cuscutae 4 parts, Radix Dipsaci 4 parts, the Cortex Eucommiae 3 parts, Radix Achyranthis Bidentatae 4 parts, Herba Epimedii 4 parts, Rhizoma Polygonati 4 parts, Fructus Corni 4 parts, Fructus Mori 3 parts, 2 parts, Radix Glycyrrhizae, Radix Et Caulis Acanthopanacis Senticosi 20 parts.
The preparation method of the Chinese medicine extract of the present embodiment is as follows:
Above-mentioned Chinese crude drug is taken by proportioning, be ground into middle powder, add above-mentioned medical material weight 6 times amount, mass fraction is the ethanol of 65%, stir, place 5 hours, transfer in percolation filtration extraction pot, add medical material weight 4 times amount, mass fraction be 45% alcoholic solution carry out seepage pressure effects, percolation speed is every kilogram of medical material collection per hour 1 liter of percolate, after extraction completes, percolate reclaims ethanol and is concentrated into medical material: the weight ratio of concentrated solution is 1:0.5, must have the Chinese medicine extract that YIN nourishing supports kidney effect.
Embodiment 4 YIN nourishing supports kidney massage cream and preparation method thereof
A kind of YIN nourishing supports kidney massage cream, its raw material composition and percentage by weight as shown in table 1, wherein phenoxyethanol/Sensiva SC50: Compositional antiseptic agent, commodity are called
pE9010; Methylisothiazolinone/chlorphenesin: Compositional antiseptic agent, model is MTC2.
Table 1 YIN nourishing supports raw material and the percentage by weight thereof of kidney massage cream
The preparation method of the present embodiment massage cream is as follows:
1, thoroughly apparatus and equipment are produced in cleaning, for subsequent use after sterilization;
2, take each component of B phase accurately, add emulsifying pot, heated and stirred, to 80-90 DEG C, is stirred to completely evenly without granule with rotating speed 30r/min, for subsequent use;
3, by C phase component heating in water bath to 90 DEG C, be stirred to complete dispersing and dissolving, insulated sterilizing 30min, overlapping 200 order filter-cloth filterings is evacuated in emulsifying pot described in step 2, stir and evacuation homogenizing 2 minutes (maintaining vacuum-0.02-0.05Mpa), become the agranular fluid of complete and homogeneous to material body;
4, accurately take each component of A phase, add in oil phase pot, be heated with stirring to 80-90 DEG C, insulated and stirred is dissolved completely to all components, for subsequent use;
5, under the mixing speed of 30r/min, the component in oil cauldron described in step 4 crossed in emulsifying pot described in 200 order filter cloth suction steps 3, evacuation, high speed homogenization 12 minutes (maintaining vacuum-0.02-0.05Mpa), stirs cooling;
6, each component of accurate weighing D phase, after mixing, cross colloid mill, circulation is milled to uniform and smooth pulpous state, for subsequent use;
7, add in emulsifying pot described in step 5 by the pre-dispersed each component of D phase of milling under the mixing speed of 30r/min, evacuation, high speed homogenization 12 minutes (maintaining vacuum-0.02-0.05Mpa), stirs cooling;
8, each component of precise E phase, mix homogeneously, is warmed to 45 DEG C to all dissolving, for subsequent use;
9, treat that each component in emulsifying pot described in step 7 is cooled to 48 DEG C, the pre-dispersed good each component of E phase is added under the mixing speed of 30r/min, abundant stirring, evacuation, high speed homogenization 32 minutes (maintaining vacuum-0.02-0.05Mpa), make product complete and homogeneous, stir mastic of lowering the temperature to obtain;
10, each component of accurate weighing F phase, treats that mastic described in step 9 is cooled to 45 DEG C, adds each component of F phase, fully stirs, evacuation, and high speed homogenization 3 minutes (maintaining vacuum-0.02-0.05Mpa), makes product complete and homogeneous, stir cooling;
11, be cooled to 37 DEG C of dischargings, sampling censorship, obtains YIN nourishing and supports kidney massage cream.
Embodiment 5 YIN nourishing supports the irritant experiment of kidney massage cream to skin
The massage cream of the embodiment of the present invention 4 is adopted to carry out acute skin irritation test to rabbit, and repeatedly irritation test.Experimental technique and step are all carried out according to the irritation test Methods and steps in " cosmetics health specification 2007 editions ".Laboratory animal is that healthy white experiment uses rabbit, body weight 2.0 ~ 3.0kg.Wherein, every rabbit health both sides, the massage cream of the present embodiment 1 is smeared in side, is experimental group; Normal saline is smeared in side, is matched group.Result of the test is in table 2 and 3.
Table 2 YIN nourishing supports the massage cream of kidney to Rabbits with Acute irritation test result
Table 3 YIN nourishing supports the massage cream of kidney to rabbit repeatedly irritation test result
From table 2 and 3 found that, YIN nourishing of the present invention supports kidney massage cream to skin without any ill effect, and acute skin irritation and repeatedly irritation test are showed no zest, and safety is high.
Embodiment 6 YIN nourishing supports the efficacy assessments of the massage cream of kidney
One, diagnostic criteria and subject's data
Diagnostic criteria: the seminal emission of dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, night sweat, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks.
Subject: the above-mentioned diagnostic criteria of tool 2, can receive as test personnel.The present embodiment test personnel totally 88: male 35 people, female 53 people, at the age: 25-55 one full year of life, is divided into test group and matched group at random, often organizes 44 people.
Two, given the test agent, sample using method and the time
Test group:
Given the test agent: the YIN nourishing of embodiment 4 supports kidney massage cream, specification is that 5g/ props up;
Service time: the time on probation is 2 weeks, every day sooner or later respectively once;
Using method: get given the test agent and be applied in Guanyuan acupoint, MINGMEN acupoint, SHENYU acupoint massage 3-5 minute in right amount.
Matched group:
Given the test agent: LIUWEI DIHUANG WAN;
Service time: the time on probation is 2 weeks, morning, noon and afternoon every day are each once;
Using method: oral, 8 balls, three times on the one.
Three, the course for the treatment of is tested: two weeks.
Four, evaluation of clinical curative effect standard
(1) effective: the seminal emission of dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, night sweat, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks make moderate progress as effective;
(2) invalid: the seminal emission of dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, night sweat, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks none be improved as invalid;
Five, result on trial analysis
YIN nourishing supports kidney massage cream 2 weeks by a definite date on probation, and subject, in Evaluation product process, does not all occur the bad phenomenon such as skin pruritus, twinge, redness.Test after terminating the course for the treatment of, test group: 39 people's dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, night sweat seminal emission, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks phenomenon make moderate progress, for effective; 5 people's dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, night sweat seminal emission, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks all without improvement, for invalid; Matched group: 34 people's dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, night sweat seminal emission, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks make moderate progress, for effective; 10 people's dizziness and tinnitus, soreness of the waist and knees, insomnia and dreamful sleep, night sweat seminal emission, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks all without improvement, for invalid.Concrete outcome is shown in Table 4:
Table 4 YIN nourishing supports kidney massage cream clinical test results
| Test group | Matched group | |
| Number | 44 | 44 |
| Effective | 39 | 34 |
| Invalid | 5 | 10 |
| Total effective rate | 88.6％ | 77.3％ |
Known by above efficacy assessments result, the massage cream being functional component with Chinese medicine extract of the present invention has the effect that significant YIN nourishing supports kidney, and its effect is better than LIUWEI DIHUANG WAN.
Each technical characteristic of the above embodiment can combine arbitrarily, for making description succinct, the all possible combination of each technical characteristic in above-described embodiment is not all described, but, as long as the combination of these technical characteristics does not exist contradiction, be all considered to be the scope that this description is recorded.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be construed as limiting the scope of the patent.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (9)
1. a YIN nourishing supports kidney Chinese medicine extract, it is characterized in that, the active component of described Chinese medicine extract is prepared from by the raw material of following weight portion: Radix Astragali 4-13 part, Radix Codonopsis 5-11 part, Ganoderma 6-14 part, Radix Angelicae Sinensis 1-5 part, Radix Paeoniae Alba 1-8 part, Radix Salviae Miltiorrhizae 1-5 part, Radix Ophiopogonis 2-7 part, Fructus Schisandrae Chinensis 1-6 part, Fructus Lycii 2-7 part, Semen Cuscutae 1-8 part, Radix Dipsaci 2-7 part, Cortex Eucommiae 1-5 part, Radix Achyranthis Bidentatae 1-8 part, Herba Epimedii 2-7 part, Rhizoma Polygonati 1-7 part, Fructus Corni 2-7 part, Fructus Mori 1-6 part, Radix Glycyrrhizae 1-5 part, Radix Et Caulis Acanthopanacis Senticosi 15-25 part.
2. YIN nourishing according to claim 1 supports kidney Chinese medicine extract, it is characterized in that, the active component of described Chinese medicine extract is prepared from by the raw material of following weight portion: Radix Astragali 7-9 part, Radix Codonopsis 7-9 part, Ganoderma 7-9 part, Radix Angelicae Sinensis 2-4 part, Radix Paeoniae Alba 4-6 part, Radix Salviae Miltiorrhizae 2-4 part, Radix Ophiopogonis 3-6 part, Fructus Schisandrae Chinensis 2-4 part, Fructus Lycii 3-5 part, Semen Cuscutae 3-5 part, Radix Dipsaci 3-5 part, Cortex Eucommiae 2-4 part, Radix Achyranthis Bidentatae 2-5 part, Herba Epimedii 3-5 part, Rhizoma Polygonati 2-6 part, Fructus Corni 3-5 part, Fructus Mori 2-4 part, Radix Glycyrrhizae 2-4 part, Radix Et Caulis Acanthopanacis Senticosi 18-22 part.
3. YIN nourishing according to claim 2 supports kidney Chinese medicine extract, it is characterized in that, the active component of described Chinese medicine extract is prepared from by the raw material of following weight portion: the Radix Astragali 8 parts, Radix Codonopsis 8 parts, Ganoderma 8 parts, Radix Angelicae Sinensis 3 parts, the Radix Paeoniae Alba 4 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Ophiopogonis 4 parts, Fructus Schisandrae Chinensis 2 parts, Fructus Lycii 4 parts, Semen Cuscutae 4 parts, Radix Dipsaci 4 parts, the Cortex Eucommiae 3 parts, Radix Achyranthis Bidentatae 4 parts, Herba Epimedii 4 parts, Rhizoma Polygonati 4 parts, Fructus Corni 4 parts, Fructus Mori 3 parts, 2 parts, Radix Glycyrrhizae, Radix Et Caulis Acanthopanacis Senticosi 20 parts.
4. the YIN nourishing described in an any one of claim 1-3 supports the preparation method of kidney Chinese medicine extract, it is characterized in that, comprise the following steps: take described raw material by proportioning, pulverize, extract with water or alcoholic solution, by extracting solution, centrifugal or filtration, obtains centrifugal liquid or filtrate, by centrifugal liquid or filtrate reduced in volume, obtain described Chinese medicine extract.
5. YIN nourishing according to claim 4 supports the preparation method of kidney Chinese medicine extract, it is characterized in that, the method for described extraction is water boiling and extraction method, ethanol ultrasonic extraction method or ethanol percolate extraction method.
6. the YIN nourishing according to claim 4 or 5 supports the preparation method of kidney Chinese medicine extract, it is characterized in that, the consumption of described water or alcoholic solution is 6-10 times of medical material weight, and the mass fraction of alcoholic solution is 25-65%; Described concentrating under reduced pressure is for being concentrated into raw material: the weight ratio of concentrated solution is 1:0.5.
7. the Chinese medicine extract described in any one of claim 1-3 has YIN nourishing in preparation and supports application in the Chinese medicine external product of kidney effect.
8. YIN nourishing supports a massage cream for kidney, it is characterized in that, described massage cream is prepared from by the Chinese medicine extract described in any one of claim 1-3 and substrate or carrier.
9. YIN nourishing according to claim 8 supports the massage cream of kidney, it is characterized in that, described massage cream is prepared from by the raw material of following percentage by weight: Chinese medicine extract described in 20%, 1.8% stereth-2, 2.0% stereth-21, 3.5% glyceryl stearate, 4.5% cetearyl alcohol, 5.0% dicaprylyl carbonate, 5.0% isopropyl myristate, 2.0% polydimethylsiloxane, 0.1% tocopherol acetas, 0.05% bisabolol, 37.48% water, 8.0%1, ammediol, 0.3% xanthan gum, 0.2% sodium alginate, 0.05% disodiumedetate, 1.0% betanin, 0.1% allantoin, 0.2% pantothenylol, 0.5% titanium dioxide, 5.0% glycerol, 2.0% butanediol, 0.02% tetrahydrochysene piperine, 0.6% Methylisothiazolinone/chlorphenesin, 0.5% phenoxyethanol/Sensiva SC50, 0.1% essence, described Chinese medicine extract is prepared from by preparation method according to claim 6.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510448269.0A CN105055849B (en) | 2015-07-24 | 2015-07-24 | Enriching yin Chinese medical extract for nourishing kidney and its preparation method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510448269.0A CN105055849B (en) | 2015-07-24 | 2015-07-24 | Enriching yin Chinese medical extract for nourishing kidney and its preparation method and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105055849A true CN105055849A (en) | 2015-11-18 |
| CN105055849B CN105055849B (en) | 2018-10-19 |
Family
ID=54485526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510448269.0A Active CN105055849B (en) | 2015-07-24 | 2015-07-24 | Enriching yin Chinese medical extract for nourishing kidney and its preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105055849B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902685A (en) * | 2016-06-13 | 2016-08-31 | 佛山市腾瑞医药科技有限公司 | Chinese patent medicine for treating and nourishing liver and kidney and preparation technology thereof |
| CN105995447A (en) * | 2016-06-01 | 2016-10-12 | 界首市雪丽种植专业合作社 | Health-preservation porridge capable of blackening hair and resisting ageing and preparation method of health-preservation porridge |
| CN108096448A (en) * | 2017-12-20 | 2018-06-01 | 厦门市沃斯格尔生物科技有限公司 | Health-care patch |
| CN110859908A (en) * | 2019-11-27 | 2020-03-06 | 佛山科学技术学院 | Traditional Chinese medicine composition for tonifying kidney and strengthening heart |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103417947A (en) * | 2013-08-19 | 2013-12-04 | 珠海圣原生物科技有限公司 | Traditional Chinese medicine extract with effect of warmly invigorating kidney yang, method for manufacturing traditional Chinese medicine extract and kidney and umbilical warming ointment |
| CN103566271A (en) * | 2012-07-28 | 2014-02-12 | 罗兴富 | Oral medicinal liquor capable of nourishing yin and yang and tonifying liver and kidney and preparation method of oral medicinal liquor |
-
2015
- 2015-07-24 CN CN201510448269.0A patent/CN105055849B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103566271A (en) * | 2012-07-28 | 2014-02-12 | 罗兴富 | Oral medicinal liquor capable of nourishing yin and yang and tonifying liver and kidney and preparation method of oral medicinal liquor |
| CN103417947A (en) * | 2013-08-19 | 2013-12-04 | 珠海圣原生物科技有限公司 | Traditional Chinese medicine extract with effect of warmly invigorating kidney yang, method for manufacturing traditional Chinese medicine extract and kidney and umbilical warming ointment |
Non-Patent Citations (1)
| Title |
|---|
| 中华人民共和国卫生部: "《化妆品卫生规范》", 31 January 2007 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105995447A (en) * | 2016-06-01 | 2016-10-12 | 界首市雪丽种植专业合作社 | Health-preservation porridge capable of blackening hair and resisting ageing and preparation method of health-preservation porridge |
| CN105902685A (en) * | 2016-06-13 | 2016-08-31 | 佛山市腾瑞医药科技有限公司 | Chinese patent medicine for treating and nourishing liver and kidney and preparation technology thereof |
| CN108096448A (en) * | 2017-12-20 | 2018-06-01 | 厦门市沃斯格尔生物科技有限公司 | Health-care patch |
| CN110859908A (en) * | 2019-11-27 | 2020-03-06 | 佛山科学技术学院 | Traditional Chinese medicine composition for tonifying kidney and strengthening heart |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105055849B (en) | 2018-10-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103417947A (en) | Traditional Chinese medicine extract with effect of warmly invigorating kidney yang, method for manufacturing traditional Chinese medicine extract and kidney and umbilical warming ointment | |
| CN104983818A (en) | Traditional Chinese medicine for treating gynecologic diseases, and preparation method thereof | |
| CN102058715B (en) | Chinese medicine preparation for treating chronic prostatitis and preparation method thereof | |
| CN101011483B (en) | Chinese medicinal formulation for treating children's digestive system disease and its preparation method | |
| CN105055849A (en) | Traditional Chinese medicine extract capable of nourishing Yin and tonifying kidney as well as preparation method and application of traditional Chinese medicine extract | |
| CN104225215A (en) | Traditional Chinese medicine for treating insomnia | |
| CN103142895B (en) | Kidney nourishing mixture and preparation method thereof | |
| CN103638199B (en) | A kind ofly prevent and treat Chinese medicine composition of neurasthenia and senile dementia and preparation method thereof | |
| CN105596861A (en) | Pill used for treating adverse reaction after CT enhancement scanning and preparation method | |
| CN102441111A (en) | Chinese patent medicine used for treating infertility, and preparation method thereof | |
| CN109464517A (en) | Clearing heat and detoxicating paediatrics external application massage ointment formula, the method and application for preparing ointment | |
| CN103405614B (en) | TCM (Traditional Chinese Medicine) composition for invigorating kidney and strengthening Yang and preparation method of TCM composition | |
| CN106620475B (en) | Traditional Chinese medicine composition for preventing and treating diabetes cognitive impairment and preparation method thereof | |
| CN105250758A (en) | Traditional Chinese medicine composition for treating diabetes | |
| CN104857377A (en) | Traditional Chinese medicine extract for improving fatty liver, preparation method of traditional Chinese medicine extract and massage cream | |
| CN103191300B (en) | External preparation of traditional Chinese medicine composition with immune function for treating dairy cow mastitis | |
| CN103285243B (en) | Granules for treating hyperglycemia | |
| CN103041017B (en) | Traditional Chinese medicine preparation for treating functional uterine bleeding and preparation method thereof | |
| CN103223098A (en) | Traditional Chinese medicine pressure reduction tea | |
| CN117860842B (en) | Acupoint patch for endometrial repair and application thereof | |
| CN107625863B (en) | Compound traditional Chinese medicine soft capsule for treating rheumatism bone disease and preparation method thereof | |
| CN104623387A (en) | Pharmaceutical composition for treating chronic nephritis | |
| CN105288473A (en) | Traditional Chinese medicine composition for treating lupus erythematosus and application thereof | |
| CN104666843A (en) | Traditional Chinese medicine composition for treating essential hypotension induced by kidney essence deficiency | |
| CN104397284A (en) | Kidney tonifying and bone strengthening eleutherococcus senticosus health tea and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190819 Address after: 519000 Third Floor of No. 3 Workshop, No. 12 Anji West Road, Sanzao Town, Jinwan District, Zhuhai City, Guangdong Province Patentee after: Guangdong Shengyuan Health Technology Co., Ltd. Address before: 519000 unit, West Whampoa Road, Guangzhou, Guangdong, China, 2706-2712, 76 Patentee before: Synsun Health Industry Co., Ltd. |