CN105055849B - Enriching yin Chinese medical extract for nourishing kidney and its preparation method and application - Google Patents
Enriching yin Chinese medical extract for nourishing kidney and its preparation method and application Download PDFInfo
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Abstract
The present invention relates to a kind of enriching yin Chinese medical extracts for nourishing kidney and its preparation method and application.The active constituent of the Chinese medical extract is prepared by the raw material of following parts by weight：4 13 parts of Radix Astragali, 5 11 parts of Radix Codonopsis, 6 14 parts of ganoderma lucidum, 15 parts of Radix Angelicae Sinensis, 18 parts of Radix Paeoniae Alba, 15 parts of Radix Salviae Miltiorrhizae, 27 parts of Radix Ophiopogonis, 16 parts of Schisandra chinensis, 27 parts of the fruit of Chinese wolfberry, 18 parts of Semen Cuscutae, 27 parts of teasel root, 15 parts of Cortex Eucommiae, 18 parts of the root of bidentate achyranthes, 27 parts of Herba Epimedii, 17 parts of sealwort, 27 parts of Fructus Corni, 16 parts of mulberries, 15 parts of Radix Glycyrrhizae, 15 25 parts of wilsonii.Using the Chinese medical extract as functional component, itself and common matrix or carrier in cosmetics are prepared into massage cream, overcome the deficiency of oral drugs, it is easy to use, and have no toxic side effect, there is enriching yin remarkable result for nourishing kidney.
Description
Technical field
The invention belongs to Chinese medicine external product fields, more particularly to a kind of enriching yin Chinese medical extract for nourishing kidney and its preparation side
Method and using the Chinese medical extract as the massage cream of main composition.
Background technology
Chinese medicine thinks that kidney is " the congenital foundation, the root of the day after tomorrow ".Kidney storing essence, essence can be changed into QI, qi leel negative and positive.Kidney yin is to internal organs
Organ plays a part of nourishing, make moist, and is the basic of human body yin-fluid；Kidney yang plays promotion, warm to zang-fu differentiation histoorgan
Effect, be the basic of human body.Kidney yin, using kidney essense as material base, maintains the relatively flat of whole negative and positive with kidney yang
Weighing apparatus.Kidney deficiency is mostly essence, gas, yin, yang loss, can, day after tomorrow mistake insufficient because of native endowment be supported, be overworked, intemperance in sexual life, prolonged illness are lost
Caused by damage etc..Common kidney essence deficiency card has：Syndrome of deficiency of kidney yang, syndrome of deficiency of kidney yin, syndrome of non-consolidation of kidney qi, edema due to the kidney insufficiency card and the failure of the kidney in receiving air
Card.Kidney deficiency is related to the different pathological stages of multiple systemic diseases such as the heart, brain, lung, kidney, liver, especially in chronic nephritis, glycosuria
The intermediary and later stages of the diseases such as disease, high blood pressure are more prominent.Therefore, correlative study is carried out to enriching yin Chinese medical extract for nourishing kidney to open
Hair has great importance.
Most of enriching yin drug for nourishing kidney is based on oral drugs on the market at present, and there are livers for Oral administration
The destruction of first pass effect and enteron aisle to drug makes the absorptivity of drug reduce, and the course for the treatment of is long, and has side effect.And externally used paste passes through
Skin be administered, containing tonify the liver and kidney, nourishes blood and promotes the production of body fluid, convergence astringent method, strengthen muscles and bones for primary efficacy effective component of chinese medicine targeting
SHENYU point is permeated, to reach enriching yin advantageous effect for nourishing kidney.External massage cream significant effect has no toxic side effect, is easy to use,
Become the administering mode that people are keen to selection.
Invention content
Based on this, an object of the present invention is to provide a kind of enriching yin Chinese medical extract for nourishing kidney.
In order to achieve the above-mentioned object of the invention, this invention takes following technical schemes：
A kind of enriching yin Chinese medical extract for nourishing kidney, the active constituent of the Chinese medical extract by following parts by weight raw material system
It is standby to form：4-13 parts of Radix Astragali, 5-11 parts of Radix Codonopsis, 6-14 parts of ganoderma lucidum, 1-5 parts of Radix Angelicae Sinensis, 1-8 parts of Radix Paeoniae Alba, 1-5 parts of Radix Salviae Miltiorrhizae, Radix Ophiopogonis 2-7
Part, 1-6 parts of Schisandra chinensis, 2-7 parts of the fruit of Chinese wolfberry, 1-8 parts of Semen Cuscutae, 2-7 parts of teasel root, 1-5 parts of Cortex Eucommiae, 1-8 parts of the root of bidentate achyranthes, Herba Epimedii 2-
7 parts, 1-7 parts of sealwort, 2-7 parts of Fructus Corni, 1-6 parts of mulberries, 1-5 parts of Radix Glycyrrhizae, 15-25 parts of wilsonii.
In wherein some embodiments, the active constituent of the Chinese medical extract prepared by the raw material of following parts by weight and
At：7-9 parts of Radix Astragali, 7-9 parts of Radix Codonopsis, 7-9 parts of ganoderma lucidum, 2-4 parts of Radix Angelicae Sinensis, 4-6 parts of Radix Paeoniae Alba, 2-4 parts of Radix Salviae Miltiorrhizae, Radix Ophiopogonis 3-6 part, the five tastes
2-4 parts sub-, 3-5 parts of the fruit of Chinese wolfberry, 3-5 parts of Semen Cuscutae, 3-5 parts of teasel root, 2-4 parts of Cortex Eucommiae, 2-5 parts of the root of bidentate achyranthes, 3-5 parts of Herba Epimedii, Huang
2-6 parts smart, 3-5 parts of Fructus Corni, 2-4 parts of mulberries, 2-4 parts of Radix Glycyrrhizae, 18-22 parts of wilsonii.
In one of the embodiments, the active constituent of the Chinese medical extract by following parts by weight raw material prepare and
At：8 parts of Radix Astragali, 8 parts of Radix Codonopsis, 8 parts of ganoderma lucidum, 3 parts of Radix Angelicae Sinensis, 4 parts of Radix Paeoniae Alba, 3 parts of Radix Salviae Miltiorrhizae, 4 parts of Radix Ophiopogonis, 2 parts of Schisandra chinensis, the fruit of Chinese wolfberry 4
Part, 4 parts of Semen Cuscutae, 4 parts of teasel root, 3 parts of Cortex Eucommiae, 4 parts of the root of bidentate achyranthes, 4 parts of Herba Epimedii, 4 parts of sealwort, 4 parts of Fructus Corni, 3 parts of mulberries, Radix Glycyrrhizae
2 parts, 20 parts of wilsonii.
The each component pharmacological action of Chinese medical extract of the present invention is as follows：
Radix Astragali：It is sweet, tepor, tonifying Qi and lifting yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema, shengjin nourishing, move stagnation and palsy, for the deficiency of vital energy it is weary
Power, anorexia and loose stool, the sinking of qi of middle-jiao, exterior deficiency spontaneous perspiration, qi deficiency edema, Heat Diabetes, blood deficiency chlorosis, numbness pain are numb.
Radix Codonopsis：Sweet and neutral, strengthening spleen and tonifying lung, nourishes blood and promotes the production of body fluid, be used for spleen-lung Qi deficiency, eat less and tired, insufficiency of vital energy and blood, sallow complexion,
Palpitation, Heat Diabetes.
Ganoderma lucidum：Sweet and neutral, invigorating qi for tranquilization, for having no peace of mind, palpitaition of having a sleepless night, consumptive disease is losed heart, do not feel like eating.
Radix Angelicae Sinensis：Sweet, pungent, warm, replenishing and activating blood, menstruction regulating and pain relieving is used for blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, Amenorrhea pain
Through, asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down.
Radix Paeoniae Alba：It is bitter, acid, be slightly cold, nourishing blood for regulating menstruation, astringing YIN to stop sweating, soft liver analgesic is used for blood deficiency chlorosis, irregular menstruation, from
Sweat, night sweat, hypochondriac pain, abdominal pain, four limbs contraction pain, dizziness of having a headache.
Radix Salviae Miltiorrhizae：Hardship is slightly cold, and promoting blood circulation is inducing meastruation to relieve menalgia, relieving restlessness that clears away heart-fire, be used for chest impediment and cardialgia, gastral cavity abdomen hypochondriac pain, it is vexed not
It sleeps, irregular menstruation, dysmenorrhoea Amenorrhea.
Radix Ophiopogonis：Sweet, slight bitter, is slightly cold, nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, is used for cough for deficiency of Yin consumptive disease, it is thirsty that mesh is hindered in Tianjin, Heat Diabetes, the heart
Tired insomnia.
Schisandra chinensis：Acid, sweet, warm, restrain astringent method, and supplementing qi and promoting the production of body fluid, tonifying kidney and calming nerves is used for emission, enuresis frequent micturition, chronic diarrhea
Incessantly, spontaneous sweating, it is thirsty that day is hindered in Tianjin, Heat Diabetes, palpitation and insomnia.
The fruit of Chinese wolfberry：Sweet and neutral, nourishing liver and kidney, benefiting shrewd head are used for consumption consumptive loss, soreness of waist and knee joint, dizziness and tinnitus, impotence something lost
Essence, Heat Diabetes, blood deficiency chlorosis, blurred vision.
Semen Cuscutae：Pungent, sweet and neutral, tonifies the liver and kidney, astringent sperm contracting urine, tocolysis, antidiarrheal, with dry kidney deficiency and liver, soreness and weakness of waist and knees, sun
Impotence is passed out semen, enuresis frequent micturition, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, blurred vision tinnitus, and spleen kidney deficiency is rushed down.
Teasel root：It is bitter, pungent, tepor, strengthening the bones and muscles, continue injured, only uterine bleeding, be used for kidney deficiency and liver, soreness and weakness of waist and knees, injury from falling down,
Injury of tendon and muscle fracture, uterine bleeding, threatened abortion.
Cortex Eucommiae：Sweet, warm, filling liver kidney, strengthening the bones and muscles, tocolysis are used for kidney deficiency and liver, and soreness of waist and knee joint, muscles and bones is powerless, dizzy mesh
It is dizzy, blood leaking in gestation, fetal irritability.
The root of bidentate achyranthes：It is bitter, sweet, sour, it puts down, filling liver kidney, strengthening the bones and muscles, inducing diuresis for treating strangurtia is ensuringd proper downward flow of the blood, and Amenorrhea, dysmenorrhoea, waist and knee acid are used for
Bitterly, muscles and bones is powerless.
Herba Epimedii：Acrid, sweet, warm, kidney-replenishing, strengthening the bones and muscles, wind-damp dispelling, be used for decline of kidney-YANG, impotence and seminal emission, muscles and bones impotence,
Arthralgia pain due to rheumatism, numbness contracture.
Sealwort：Sweet and neutral, boosting qi and nourishing yin, kidney-nourishing are used for deficiency of spleen-QI and stomach-QI, fatigue and asthenia, deficiency of stomach-Yin, asthenia of essence and blood, waist and knee
It is aching and limp, Heat Diabetes.
Fructus Corni：Sour, puckery, tepor tonifies the liver and kidney, arresting collape syndrome by astringents, is used for dizziness and tinnitus, soreness of waist and knee joint, and impotence and seminal emission is lost
Frequent micturition is urinated, under uterine bleeding band, profuse sweating collapse, Heat Diabetes.
Mulberries：It is sweet, sour, it trembles with fear, nourishing yin and supplementing blood, fluid dryness is used for the deficiency of liver-yin and kidney-yin, dizziness and tinnitus, palpitation and insomnia, Tianjin wound
Yearningly, Heat Diabetes.
Radix Glycyrrhizae：Sweet and neutral is invigorated the spleen and benefited qi, relieving spasm to stop pain, coordinating the drug actions of a prescription, be used for weakness of the spleen and the stomach, lassitude hypodynamia, palpitation,
Gastral cavity abdomen, four limbs contraction.
Wilsonii：Pungent, slight bitter, temperature, tonifies the kidney to relieve mental strain, and is used for physically weak weak, deficiency of both the lung and kidney, kidney deficiency soreness of waist and knee joint.
Another object of the present invention is to provide the preparation methods that kidney Chinese medical extract is supported in above-mentioned enriching yin.
Specific technical solution is as follows：
The preparation method of kidney Chinese medical extract is supported in a kind of above-mentioned enriching yin, is included the following steps：The raw material is weighed according to the ratio,
It crushes, is extracted with water or ethanol solution, extracting solution is centrifuged or filtered, centrifugate or filtrate are obtained, by centrifugate or filtrate
It is concentrated under reduced pressure to get the Chinese medical extract.
In wherein some embodiments, the method for the extraction is water boiling and extraction method, EtOH Sonicate extraction method or ethyl alcohol
Permeating extraction.
In wherein some embodiments, the dosage of the water or ethanol solution is 6-10 times of medicinal material weight, ethanol solution
Mass fraction be 25-65%；It is described to be concentrated under reduced pressure to be concentrated into raw material：The weight ratio of concentrate is 1:0.5.
Another object of the present invention is to provide the applications of above-mentioned Chinese medical extract.
Specific technical solution is as follows：
Application of the above-mentioned Chinese medical extract in preparing the Chinese medicine external product that there is enriching yin to support kidney effect.
Another object of the present invention is to provide a kind of enriching yin massage cream for nourishing kidney.
Specific technical solution is as follows：
A kind of enriching yin massage cream for nourishing kidney often uses base by the above-mentioned Chinese medical extract and cosmetics as main composition
Matter or carrier are prepared.
In wherein some embodiments, the massage cream is prepared by the raw material of following weight percent：20% is above-mentioned
Chinese medical extract, 1.8% stereth -2,2.0% stereth -21,3.5% stearine, 4.5% spermaceti are hard
Lipidol, 5.0% carbonic acid dioctyl ester, 5.0% isopropyl myristate, 2.0% dimethyl silicone polymer, 0.1% tocopheryl acetate
Ester, 0.05% bisabolol, 37.48% water, 8.0%1,3- propylene glycol, 0.3% xanthans, 0.2% mosanom, 0.05% second
Edetate disodium, 1.0% glycine betaine, 0.1% allantoin, 0.2% panthenol, 0.5% titanium dioxide, 5.0% glycerine,
2.0% butanediol, 0.02% tetrahydrochysene pipering, 0.6% methylisothiazolinone/Chlorphenesin, 0.5% Phenoxyethanol/ethyl
Hexyl glycerine, 0.1% essence.
The invention has the advantages that：
Chinese medical extract provided by the invention has the function of tonifying the kidney to relieve mental strain, nourishing liver blood-nourishing, strengthening the spleen and replenishing qi, can effectively delay
The symptoms such as dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep, hectic fever night sweat, dysphoria in chestpalms-soles.It will be normal in the Chinese medical extract and cosmetics
It is prepared into external massage cream with matrix or carrier, overcomes the deficiency that kidney oral drugs are supported in the enriching yin in above-mentioned background technology, institute
It states massage cream have no toxic side effect, is easy to use, by way of percutaneous dosing, the active ingredient targeting in Chinese medical extract is oozed
Saturating Guanyuan point, MINGMEN acupoint, SHENYU point, to reach enriching yin remarkable result for nourishing kidney.
Specific implementation mode
Below with reference to specific embodiment, the invention will be further described.
A kind of 1 enriching yin Chinese medical extract for nourishing kidney of embodiment
The enriching yin Chinese medical extract for nourishing kidney of the present embodiment is prepared by the raw material of following parts by weight：4 parts of Radix Astragali, Radix Codonopsis
5 parts, it is 14 parts of ganoderma lucidum, 1 part of Radix Angelicae Sinensis, 1 part of Radix Paeoniae Alba, 5 parts of Radix Salviae Miltiorrhizae, 7 parts of Radix Ophiopogonis, 6 parts of Schisandra chinensis, 2 parts of the fruit of Chinese wolfberry, 8 parts of Semen Cuscutae, continuous
2 parts disconnected, 1 part of Cortex Eucommiae, 8 parts of the root of bidentate achyranthes, 2 parts of Herba Epimedii, 1 part of sealwort, 7 parts of Fructus Corni, 6 parts of mulberries, 1 part of Radix Glycyrrhizae, 25 parts of wilsonii.
The preparation method of the Chinese medical extract of the present embodiment is as follows：
Above-mentioned Chinese medicine is weighed according to the ratio, is crushed, and 8 times of amounts of medicinal material weight, the ethanol solution that mass fraction is 25% is added
Ultrasonic extraction 2 times, merges No. 2 extracting solutions, extracting solution low-speed centrifugal, and high speed centrifugation in centrifugate collects high speed centrifugation liquid, decompression
Concentration, is concentrated into medicinal material：The weight ratio of concentrate is 1:0.5 to get supporting the Chinese medical extract of kidney effect with enriching yin.
A kind of 2 enriching yin Chinese medical extract for nourishing kidney of embodiment
The enriching yin Chinese medical extract for nourishing kidney of the present embodiment is prepared by the raw material of following parts by weight：13 parts of Radix Astragali, party
Ginseng 11 parts, 6 parts of ganoderma lucidum, 5 parts of Radix Angelicae Sinensis, 8 parts of Radix Paeoniae Alba, 1 part of Radix Salviae Miltiorrhizae, 2 parts of Radix Ophiopogonis, 1 part of Schisandra chinensis, 7 parts of the fruit of Chinese wolfberry, 1 part of Semen Cuscutae,
7 parts of teasel root, 5 parts of Cortex Eucommiae, 1 part of the root of bidentate achyranthes, 7 parts of Herba Epimedii, 7 parts of sealwort, 2 parts of Fructus Corni, 1 part of mulberries, 5 parts of Radix Glycyrrhizae, wilsonii 15
Part.
The preparation method of the Chinese medical extract of the present embodiment is as follows：
Above-mentioned Chinese medicine is weighed according to the ratio, is crushed, and 6 times of the medicinal material weight water boiling and extraction measured 2 times, extracting solution filter is added
It crosses, is concentrated into medicinal material：The weight ratio of concentrate is 1:0.5 supports the Chinese medical extract that kidney function is imitated to get with enriching yin.
A kind of 3 enriching yin Chinese medical extract for nourishing kidney of embodiment
The enriching yin Chinese medical extract for nourishing kidney of the present embodiment is prepared by the raw material of following parts by weight：8 parts of Radix Astragali, Radix Codonopsis
8 parts, it is 8 parts of ganoderma lucidum, 3 parts of Radix Angelicae Sinensis, 4 parts of Radix Paeoniae Alba, 3 parts of Radix Salviae Miltiorrhizae, 4 parts of Radix Ophiopogonis, 2 parts of Schisandra chinensis, 4 parts of the fruit of Chinese wolfberry, 4 parts of Semen Cuscutae, continuous
4 parts disconnected, 3 parts of Cortex Eucommiae, 4 parts of the root of bidentate achyranthes, 4 parts of Herba Epimedii, 4 parts of sealwort, 4 parts of Fructus Corni, 3 parts of mulberries, 2 parts of Radix Glycyrrhizae, 20 parts of wilsonii.
The preparation method of the Chinese medical extract of the present embodiment is as follows：
Above-mentioned Chinese medicine is weighed according to the ratio, is ground into middle powder, and above-mentioned medicinal material weight 6 times of amounts, mass fractions 65% are added
Ethyl alcohol, stir evenly, place 5 hours, transfer in percolation filtration extraction pot, medicinal material weight 4 times of amounts, mass fractions, which are added, is
45% ethanol solution carries out seepage pressure effects, and diacolation speed is that every kilogram of medicinal material collects 1 liter of percolate per hour, and extraction is completed
Afterwards, percolate recycles ethyl alcohol and is concentrated into medicinal material：The weight ratio of concentrate is 1:0.5 supports to get with enriching yin in kidney function effect
Medicament extract.
Kidney massage cream and preparation method thereof is supported in 4 enriching yin of embodiment
A kind of foster kidney massage cream of enriching yin, raw material composition and its weight percent are as shown in table 1, wherein Phenoxyethanol/second
Base hexyl glycerine：Compositional antiseptic agent, trade namePE 9010；Methylisothiazolinone/Chlorphenesin：Compounding is anti-
Rotten agent, model MTC2.
The raw material and its weight percent of kidney massage cream are supported in 1 enriching yin of table
The preparation method of the present embodiment massage cream is as follows：
1, it thoroughly cleans and produces apparatus and equipment, it is spare after sterilization；
2, each component of B phases is accurately weighed, emulsification pot is added, heating stirring is to 80-90 DEG C, with rotating speed 30r/min
It stirs to substantially uniformity without particle, it is spare；
3, by C phase components heating water bath to 90 DEG C, stirring is filtered to dissolving, insulated sterilizing 30min, 200 mesh of set are completely dispersed
Cloth filtering is evacuated to described in step 2 and emulsifies in pot, stirs and vacuumizes homogeneous 2 minutes (maintaining vacuum -0.02-0.05Mpa), until material
Body becomes the agranular fluid of complete and homogeneous；
4, accurate to weigh each component of A phases, it is added in oil phase pot, is heated with stirring to 80-90 DEG C, insulated and stirred is to all groups
Divide and is completely dissolved, it is spare；
5, under the mixing speed of 30r/min, the component in oil cauldron described in step 4 is crossed into 200 mesh filter clothes and is pumped into step 3 institute
It states in emulsification pot, vacuumizes, high speed homogenization 12 minutes (maintaining vacuum -0.02-0.05Mpa), stirring cooling；
6, accurate weighing D phases each component after mixing, crosses colloid mill, cycle is milled to uniform and smooth pulpous state, spare；
7, the pre-dispersed D phase each components milled are added described in step 5 under the mixing speed of 30r/min and emulsify pot
In, it vacuumizes, high speed homogenization 12 minutes (maintaining vacuum -0.02-0.05Mpa), stirring cooling；
8, precise E phases each component is uniformly mixed, is warmed to 45 DEG C to whole dissolvings, spare；
9, it waits for that each component emulsified described in step 7 in pot is cooled to 48 DEG C, pre- point is added under the mixing speed of 30r/min
The E phase each components dissipated, are sufficiently stirred, vacuumize, and high speed homogenization 32 minutes (maintaining vacuum -0.02-0.05Mpa) makes product
Complete and homogeneous stirs the lotion that cools down to obtain；
10, each component of accurate weighing F phases waits for that lotion described in step 9 is cooled to 45 DEG C, each component of F phases is added, fills
Divide stirring, vacuumize, high speed homogenization 3 minutes (maintaining vacuum -0.02-0.05Mpa) makes product complete and homogeneous, stirring cooling；
11,37 DEG C of dischargings are cooled to, sampling inspection supports kidney massage cream to get enriching yin.
Irritant experiment of the kidney massage cream to skin is supported in 5 enriching yin of embodiment
Acute skin irritation experiment, and repeatedly skin thorn are carried out to rabbit using the massage cream of the embodiment of the present invention 4
Swash property experiment.Experimental method and step according to《Cosmetics health specification 2007 editions》In skin irritation test method with step
It is rapid to carry out.Experimental animal is health white experiment rabbit, 2.0~3.0kg of weight.Wherein, every rabbit body both sides, side apply
The massage cream of the present embodiment 1 is smeared, is experimental group；Physiological saline is smeared in side, is control group.Test result is shown in Table 2 and 3.
2 enriching yin of table massage cream for nourishing kidney is to Rabbits with Acute skin irritation test result
3 enriching yin of table massage cream for nourishing kidney is to the multiple skin irritation test result of rabbit
From table 2 and 3 as a result, it has been found that, enriching yin of the invention support kidney massage cream there is no any ill-effect to skin, it is acute
Skin irritation and multiple skin irritation test are showed no irritation, and safety is high.
The effect of 6 enriching yin of embodiment massage cream for nourishing kidney, is evaluated
One, diagnostic criteria and subject's data
Diagnostic criteria：Dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep, night sweat seminal emission, dysphoria in chestpalms-soles, dry throat cheekbone is red.
Subject：Has above-mentioned diagnostic criteria 2, you can receive as test personnel.The present embodiment test personnel totally 88：Man
35 people, 53 people of female, age：25-55 one full year of life is randomly divided into test group and control group, every group of 44 people.
Two, given the test agent, sample application method and time
Test group：
Given the test agent：Kidney massage cream is supported in the enriching yin of embodiment 4, and specification is 5g/ branch；
Usage time：Time on probation is 2 weeks, once in the morning and once at night；
Application method：It takes given the test agent to be applied to Guanyuan point, MINGMEN acupoint, Shen Shu point in right amount to massage 3-5 minutes.
Control group：
Given the test agent：Liuwei Dihuang Wan；
Usage time：Time on probation is 2 weeks, each primary in the morning, afternoon and evening daily；
Application method：It is oral, 8 balls, three times per day.
Three, the course for the treatment of is tested：Two weeks.
Four, evaluation of clinical curative effect standard
(1) effective：Dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep, night sweat seminal emission, dysphoria in chestpalms-soles, dry throat cheekbone is red makes moderate progress
It is effective；
(2) invalid：Dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep, night sweat seminal emission, dysphoria in chestpalms-soles, none red improvement of dry throat cheekbone
It is invalid；
Five, result on trial is analyzed
It is 2 weeks by a definite date on probation that kidney massage cream is supported in enriching yin, subject during Evaluation product, do not occur pruitus,
The bad phenomenons such as shouting pain, redness.After testing the course for the treatment of, test group：39 people's dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep, night sweat
Seminal emission, dysphoria in chestpalms-soles, the red phenomenon of dry throat cheekbone make moderate progress, and are effective；5 people's dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep, night sweat
Seminal emission, dysphoria in chestpalms-soles, dry throat cheekbone is red without improvement, is invalid；Control group：34 people's dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep,
Night sweat, which is passed out semen, dysphoria in chestpalms-soles, dry throat cheekbone is red makes moderate progress, and is effective；10 people's dizziness and tinnitus, soreness and weakness of waist and knees, insomnia and dreamful sleep, night sweat
Seminal emission, dysphoria in chestpalms-soles, dry throat cheekbone is red without improvement, is invalid.Concrete outcome is shown in Table 4：
Kidney massage cream clinical test results are supported in 4 enriching yin of table
| Test group | Control group | |
| Number | 44 | 44 |
| It is effective | 39 | 34 |
| In vain | 5 | 10 |
| Total effective rate | 88.6% | 77.3% |
By above effect evaluation result it is found that having as the massage cream of functional component using the Chinese medical extract of the present invention
Significant enriching yin effect for nourishing kidney, and its effect is better than Liuwei Dihuang Wan.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, it is all considered to be the range of this specification record.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection of the present invention
Range.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (5)
1. kidney Chinese medical extract is supported in a kind of enriching yin, which is characterized in that the active constituent of the Chinese medical extract is by following parts by weight
Raw material be prepared：4-13 parts of Radix Astragali, 5-11 parts of Radix Codonopsis, 6-14 parts of ganoderma lucidum, 1-5 parts of Radix Angelicae Sinensis, 1-8 parts of Radix Paeoniae Alba, Radix Salviae Miltiorrhizae 1-5
Part, Radix Ophiopogonis 2-7 part, 1-6 parts of Schisandra chinensis, 2-7 parts of the fruit of Chinese wolfberry, 1-8 parts of Semen Cuscutae, 2-7 parts of teasel root, 1-5 parts of Cortex Eucommiae, root of bidentate achyranthes 1-8
Part, 2-7 parts of Herba Epimedii, 1-7 parts of sealwort, 2-7 parts of Fructus Corni, 1-6 parts of mulberries, 1-5 parts of Radix Glycyrrhizae, 15-25 parts of wilsonii；
The preparation method of kidney Chinese medical extract is supported in the enriching yin, is included the following steps：The raw material is weighed according to the ratio, is crushed,
It is extracted with water or ethanol solution, extracting solution is centrifuged or filtered, centrifugate or filtrate are obtained, centrifugate or filtrate decompression is dense
Contracting is to get the Chinese medical extract；The dosage of the water or ethanol solution is 6-10 times of medicinal material weight, the quality of ethanol solution
Score is 25-65%；It is described to be concentrated under reduced pressure to be concentrated into raw material：The weight ratio of concentrate is 1:0.5.
2. kidney Chinese medical extract is supported in enriching yin according to claim 1, which is characterized in that the activity of the Chinese medical extract at
Divide and is prepared by the raw material of following parts by weight：7-9 parts of Radix Astragali, 7-9 parts of Radix Codonopsis, 7-9 parts of ganoderma lucidum, 2-4 parts of Radix Angelicae Sinensis, Radix Paeoniae Alba 4-6
Part, 2-4 parts of Radix Salviae Miltiorrhizae, Radix Ophiopogonis 3-6 part, 2-4 parts of Schisandra chinensis, 3-5 parts of the fruit of Chinese wolfberry, 3-5 parts of Semen Cuscutae, 3-5 parts of teasel root, Cortex Eucommiae 2-4
Part, 2-5 parts of the root of bidentate achyranthes, 3-5 parts of Herba Epimedii, 2-6 parts of sealwort, 3-5 parts of Fructus Corni, 2-4 parts of mulberries, 2-4 parts of Radix Glycyrrhizae, wilsonii 18-
22 parts.
3. kidney Chinese medical extract is supported in enriching yin according to claim 2, which is characterized in that the activity of the Chinese medical extract at
Divide and is prepared by the raw material of following parts by weight：8 parts of Radix Astragali, 8 parts of Radix Codonopsis, 8 parts of ganoderma lucidum, 3 parts of Radix Angelicae Sinensis, 4 parts of Radix Paeoniae Alba, 3 parts of Radix Salviae Miltiorrhizae,
4 parts of Radix Ophiopogonis, 2 parts of Schisandra chinensis, 4 parts of the fruit of Chinese wolfberry, 4 parts of Semen Cuscutae, 4 parts of teasel root, 3 parts of Cortex Eucommiae, 4 parts of the root of bidentate achyranthes, 4 parts of Herba Epimedii, sealwort 4
Part, 4 parts of Fructus Corni, 3 parts of mulberries, 2 parts of Radix Glycyrrhizae, 20 parts of wilsonii.
4. claim 1-3 any one of them Chinese medical extract is in preparing the Chinese medicine external product that there is enriching yin to support kidney effect
Application.
5. a kind of enriching yin massage cream for nourishing kidney, which is characterized in that the massage cream is by claim 1-3 any one of them Chinese medicines
Extract and matrix or carrier are prepared.
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| CN105902685A (en) * | 2016-06-13 | 2016-08-31 | 佛山市腾瑞医药科技有限公司 | Chinese patent medicine for treating and nourishing liver and kidney and preparation technology thereof |
| CN108096448A (en) * | 2017-12-20 | 2018-06-01 | 厦门市沃斯格尔生物科技有限公司 | Health-care patch |
| CN110859908A (en) * | 2019-11-27 | 2020-03-06 | 佛山科学技术学院 | Traditional Chinese medicine composition for tonifying kidney and strengthening heart |
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| CN103566271A (en) * | 2012-07-28 | 2014-02-12 | 罗兴富 | Oral medicinal liquor capable of nourishing yin and yang and tonifying liver and kidney and preparation method of oral medicinal liquor |
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| CN103566271A (en) * | 2012-07-28 | 2014-02-12 | 罗兴富 | Oral medicinal liquor capable of nourishing yin and yang and tonifying liver and kidney and preparation method of oral medicinal liquor |
| CN103417947A (en) * | 2013-08-19 | 2013-12-04 | 珠海圣原生物科技有限公司 | Traditional Chinese medicine extract with effect of warmly invigorating kidney yang, method for manufacturing traditional Chinese medicine extract and kidney and umbilical warming ointment |
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